phenylbutazone has been researched along with Liver Neoplasms in 10 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Uncommon tubular cell tumors of the kidney were found in 13 exposed rats: 5 in the 50 mg group and 4 in the 100 mg group of males; 4 in dosed female rats; none in controls." | 1.29 | Long-term exposure to the anti-inflammatory agent phenylbutazone induces kidney tumors in rats and liver tumors in mice. ( Bucher, J; Eustis, S; Haseman, J; Huff, J; Kari, F, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CONNEY, AH | 1 |
| BURNS, JJ | 1 |
| Park, WH | 1 |
| Joo, ST | 1 |
| Park, KK | 1 |
| Chang, YC | 1 |
| Kim, CH | 1 |
| Kari, F | 1 |
| Bucher, J | 1 |
| Haseman, J | 1 |
| Eustis, S | 1 |
| Huff, J | 1 |
| González Macias, J | 1 |
| Herreros Fernández, V | 1 |
| De Castro Del Pozo, S | 1 |
| Liu, LM | 1 |
| Yu, EX | 1 |
| Yanagi, S | 1 |
| Sakamoto, M | 1 |
| Takahashi, S | 1 |
| Tsutsumi, M | 1 |
| Konishi, Y | 1 |
| Shibata, K | 1 |
| Kamiya, T | 1 |
| Delaveirre, PH | 1 |
| Hureau, J | 1 |
| Grivaux, M | 1 |
| Chretien, J | 1 |
| Etienne, JP | 1 |
| Coppo, M | 1 |
| Agnolucci, MT | 1 |
| Gershbein, LL | 1 |
1 review available for phenylbutazone and Liver Neoplasms
| Article | Year |
|---|---|
More about isonicotinic acid hydrazide toxicity.
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma; Chemical and Drug Induced Liver Injury; C | 1970 |
9 other studies available for phenylbutazone and Liver Neoplasms
| Article | Year |
|---|---|
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; | 1963 |
Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepat | 2004 |
Long-term exposure to the anti-inflammatory agent phenylbutazone induces kidney tumors in rats and liver tumors in mice.
Topics: Adenoma; Animals; Corn Oil; Female; Hyperplasia; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; M | 1995 |
[Metabolic capacity of the liver for drugs in hepatobiliary patients].
Topics: Adolescent; Adult; Biliary Tract Diseases; Body Weight; Female; Humans; Injections, Intramuscular; L | 1975 |
[Comprehensive "4-step analgesic ladder" therapy in treating cancer-related pain-analysis of 486 cases].
Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Drugs, Chinese Herbal; Female; Humans; Indomethac | 1992 |
Promotion of hepatocarcinogenesis by suxibuzone in rats initiated with 3'-methyl-4-dimethylaminoazobenzene.
Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Drug Interactions; Liver; Liver Neoplasms; | 1987 |
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; In | 1973 |
[Acute reactive aspecific hepatitis].
Topics: Adolescent; Aged; Cholelithiasis; Hepatitis; Humans; Liver Neoplasms; Male; Middle Aged; Phenylbutaz | 1966 |
Effect of various agents on liver regeneration and Walker tumor growth in partially hepatectomized rats.
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Benzofurans; Carcinoma 256, Walker; Cortisone; D | 1966 |