phenylbutazone has been researched along with Leukopenia in 11 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Among the drugs tested chloramphenicol, thiamphenicol, and chlorpromazine were inhibitory in therapeutic concentrations, a finding consistent with the common occurrence of a dose-dependent leukopenia from these drugs." | 3.65 | Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor. ( Gross, MA; Yunis, AA, 1975) |
| "Two examples of hematological toxicity following phenylbutazone therapy are described, one of agranulocytosis and one of aplastic anemia." | 3.64 | HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES. ( CHALMERS, TM; MCCARTHY, DD, 1964) |
| "Aminopyrine alone was responsible for eight cases." | 1.24 | Agranulocytosis: a report of 30 cases. ( Colpron, G; Gosselin, G; Long, LA; Pretty, HM, 1965) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WEISSMANN, G | 1 |
| XEFTERIS, ED | 1 |
| WALCZAK, H | 1 |
| MCCARTHY, DD | 1 |
| CHALMERS, TM | 1 |
| Fraumeni, JF | 1 |
| Naess, K | 1 |
| Grayson, MF | 1 |
| Martin, VM | 1 |
| Markham, RL | 1 |
| Yunis, AA | 1 |
| Gross, MA | 1 |
| Rachmilewitz, M | 1 |
| Schick, P | 1 |
| Trepel, F | 1 |
| Begemann, H | 1 |
| Burns, SL | 1 |
| Pretty, HM | 1 |
| Gosselin, G | 1 |
| Colpron, G | 1 |
| Long, LA | 1 |
1 review available for phenylbutazone and Leukopenia
| Article | Year |
|---|---|
Disorders of the blood in changing environmental conditions.
Topics: Agranulocytosis; Aminopyrine; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Antibody F | 1970 |
10 other studies available for phenylbutazone and Leukopenia
| Article | Year |
|---|---|
Phenylbutazone leukopenia.
Topics: Humans; Leukocyte Count; Leukocyte Disorders; Leukopenia; Phenylbutazone | 1959 |
[ON THE TREATMENT OF DIFFERENT TYPES OF RHEUMATIC DISEASES IN PULMONARY TUBERCULOSIS AND LUNG TUMORS].
Topics: Agranulocytosis; Aminosalicylic Acid; Aminosalicylic Acids; Isoniazid; Leukopenia; Lung; Lung Neopla | 1964 |
HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES.
Topics: Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Arthritis; Arthr | 1964 |
Bone marrow depression induced by chloramphenicol or phenylbutazone. Leukemia and other sequelae.
Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Follow-Up Studies; Hemorrhage; Humans; Infe | 1967 |
[Leukopenia and agranulocytosis induced by drugs].
Topics: Agranulocytosis; Antithyroid Agents; Chlorpromazine; Humans; Leukopenia; Phenylbutazone; Thiourea | 1976 |
Antinative DNA antibodies as a reaction to pyrazole drugs.
Topics: Antibodies; Antibodies, Antinuclear; Antistreptolysin; Binding Sites; Binding Sites, Antibody; Human | 1975 |
Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Chloramphenicol; Chlorpromazine; Clone Cells | 1975 |
[Morphological and functional alterations of the blood cell system of guinea pigs after treatment with cytostatic agents, prednisolone and phenylbutazone. I. Alterations of different leukocyte and lymphocyte subgroups in the blood].
Topics: Animals; Antineoplastic Agents; Blood Cells; Cyclophosphamide; Dactinomycin; Guinea Pigs; Leukocytes | 1968 |
Anemia in rheumatoid arthritis.
Topics: Anemia; Arthritis, Rheumatoid; Chronic Disease; Female; Gastrointestinal Hemorrhage; Glucocorticoids | 1968 |
Agranulocytosis: a report of 30 cases.
Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Aspirin; Bone Marrow; Bone Marrow Examination; Chlorproma | 1965 |