phenylbutazone has been researched along with Leukemia in 41 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two examples of hematological toxicity following phenylbutazone therapy are described, one of agranulocytosis and one of aplastic anemia." | 3.64 | HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES. ( CHALMERS, TM; MCCARTHY, DD, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LASKINA, SM | 1 |
| TUZSON, P | 1 |
| KERTAI, P | 1 |
| PETROVA, TR | 1 |
| WOODLIFF, HJ | 6 |
| DOUGAN, L | 5 |
| CHALMERS, TM | 2 |
| MCCARTHY, DD | 2 |
| CREPALDI, G | 1 |
| PARPAJOLA, A | 1 |
| WIEK, K | 1 |
| INNIS, MD | 1 |
| BRICOUT, P | 1 |
| LONG, LA | 1 |
| COLPRON, G | 1 |
| GOSSELIN, G | 1 |
| DOAN, CA | 1 |
| THORPE, GJ | 1 |
| THORLING, EB | 1 |
| HART, GD | 2 |
| CHATTERJEA, JB | 1 |
| GOLDING, JR | 1 |
| HAMILTON, MG | 1 |
| MOODY, HE | 1 |
| Fraumeni, JF | 1 |
| Adamson, RH | 1 |
| Seiber, SM | 1 |
| Friedman, GD | 1 |
| Murray, RO | 1 |
| Chaplin, S | 1 |
| Calabro, JJ | 2 |
| Katz, RM | 1 |
| Maltz, BA | 2 |
| Potolsky, A | 1 |
| Creger, WP | 1 |
| Sbarra, AJ | 1 |
| Paul, BB | 1 |
| Jacobs, AA | 1 |
| Strauss, RR | 1 |
| Mitchell, GW | 1 |
| Mey, U | 1 |
| Forni, A | 1 |
| Vigliani, EC | 1 |
| Hartwich, G | 1 |
| Lutz, H | 1 |
| Gebauer, D | 1 |
| Jensen, MK | 1 |
| Roll, K | 1 |
| Leavesley, GM | 1 |
| Stenhouse, NS | 2 |
| Roth, L | 1 |
| Chiriţă, P | 1 |
| Georgescu, L | 1 |
| Tudose, N | 1 |
| Coeur, P | 1 |
| Blessinger, GM | 1 |
| Keiser, G | 1 |
| Walder, HR | 1 |
| Sims, JA | 1 |
6 reviews available for phenylbutazone and Leukemia
| Article | Year |
|---|---|
Chemically induced leukemia in humans.
Topics: Benzene; Chlorambucil; Chloramphenicol; Cyclophosphamide; Humans; Leukemia; Melphalan; Phenylbutazon | 1981 |
Bone marrow depression due to mianserin, phenylbutazone, oxyphenbutazone, and chloramphenicol--Part II.
Topics: Anemia, Aplastic; Bone Marrow; Chloramphenicol; Dose-Response Relationship, Drug; Erythropoiesis; Hu | 1986 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
Role of the phagocyte in host-parasite interactions. 38. Metabolic activities of the phagocyte as related to antimicrobial action.
Topics: Animals; Bacteria; Blood Bactericidal Activity; Bone Marrow; Bone Marrow Cells; Female; Fungi; Gluco | 1972 |
[Etiology of human leukemias].
Topics: Age Factors; Benzene; Cell Transformation, Neoplastic; Chloramphenicol; Hematopoietic Stem Cells; Hu | 1974 |
Chemical leukemogenesis in man.
Topics: Anemia, Aplastic; Benzene; Benzene Derivatives; Bone Marrow; Bone Marrow Cells; Chloramphenicol; Hum | 1974 |
35 other studies available for phenylbutazone and Leukemia
| Article | Year |
|---|---|
[Leukemoid reaction with lymphoadenopathy during butadione therapy].
Topics: Disease; Humans; Leukemia; Leukemoid Reaction; Lymph Nodes; Lymphatic Diseases; Phenylbutazone | 1959 |
[The capacity of different organs to transform corticoids in experimental viral leukemia].
Topics: Adrenal Cortex Hormones; Animals; Avian Leukosis Virus; Cortisone; Humans; Hydrocortisone; Leukemia; | 1963 |
[ON THE ACTION OF BUTADION IN LYMPHOGRANULOMATOSIS AND CHRONIC LEUKEMIA].
Topics: Antineoplastic Agents; Hodgkin Disease; Leukemia; Phenylbutazone; Sarcoidosis | 1963 |
ACUTE LEUKAEMIA ASSOCIATED WITH PHENYLBUTAZONE TREATMENT.
Topics: Arthritis; Geriatrics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocytes; Phenylbutazone; | 1964 |
PHENYLBUTAZONE THERAPY ASSOCIATED WITH LEUKAEMIA.
Topics: Arthritis; Arthritis, Rheumatoid; Leukemia; Leukemia, Myeloid; Penicillins; Phenylbutazone; Toxicolo | 1964 |
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Ky | 1964 |
[ON THE CLINICAL ASPECTS OF AGRANULOCYTOSIS].
Topics: Agranulocytosis; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chlorpromazine; Dr | 1964 |
PHENYLBUTAZONE AND LEUKAEMIA.
Topics: Arthritis; Arthritis, Rheumatoid; Leukemia; Leukemia, Myeloid; Phenylbutazone; Toxicology | 1964 |
[ACUTE LEUKEMIA. (STUDY OF A SERIES OF 70 CASES)].
Topics: Acute Disease; Humans; Leukemia; Phenylbutazone; Statistics as Topic | 1964 |
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Coba | 1964 |
HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES.
Topics: Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Arthritis; Arthr | 1964 |
LEUKAEMIA AND PHENYLBUTAZONE.
Topics: Agranulocytosis; Anemia; Anemia, Aplastic; Leukemia; Leukemoid Reaction; Phenylbutazone; Subarachnoi | 1964 |
[LEUKEMIC MYELOMATOSIS. PLASMATOCYTIC LEUKEMIA. REPORT OF A CASE].
Topics: Adrenal Cortex Hormones; Blood Protein Electrophoresis; Bone Marrow Examination; Classification; Hum | 1964 |
LEUKAEMIA AND PHENYLBUTAZONE.
Topics: Back Pain; Diagnosis; Intervertebral Disc Displacement; Leukemia; Leukemia, Myeloid; Phenylbutazone; | 1964 |
ACUTE LEUKEMIA FOLLOWING PHENYLBUTAZONE THERAPY.
Topics: Drug Therapy; Leukemia; Leukemia, Myeloid; Neoplasms; Phenylbutazone; Toxicology | 1964 |
LEUKAEMIA AND PHENYLBUTAZONE.
Topics: Bone Diseases; Collagen Diseases; Leukemia; Leukemia, Myeloid; Neoplasms; Phenylbutazone; Toxicology | 1964 |
PHENYLBUTAZONE AND LEUKAEMIA.
Topics: Arthritis; Arthritis, Rheumatoid; Leukemia; Neoplasms; Phenylbutazone; Spondylitis; Spondylitis, Ank | 1965 |
ACUTE LEUKAEMIA ASSOCIATED WITH PHENYLBUTAZONE TREATMENT: A REVIEW OF THE LITERATURE AND REPORT OF A FURTHER CASE.
Topics: Acute Disease; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Leukemia; Leukemia, Lymphoid; Phenylb | 1965 |
ACUTE LEUKAEMIA AND PHENYLBUTAZONE.
Topics: Acute Disease; Leukemia; Phenylbutazone; Toxicology | 1965 |
MONOCYTIC LEUKAEMIA AND PHENYLBUTAZONE.
Topics: Arthritis; Arthritis, Rheumatoid; Drug Therapy; Genetics, Medical; Leukemia; Leukemia, Monocytic, Ac | 1965 |
[LEUKEMIA AND PHENYLBUTAZONE?].
Topics: Drug Therapy; Leukemia; Phenylbutazone; Toxicology | 1965 |
Bone marrow depression induced by chloramphenicol or phenylbutazone. Leukemia and other sequelae.
Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Follow-Up Studies; Hemorrhage; Humans; Infe | 1967 |
Phenylbutazone, musculoskeletal disease, and leukemia.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Aged; Bone Diseases; Delivery of Health Care; Diazepa | 1982 |
Iatrogenic lesions of the skeleton. Caldwell lecture, 1975.
Topics: Adolescent; Aged; Anesthesia; Bone and Bones; Bone Diseases; Child; Cortisone; Female; Fracture Fixa | 1976 |
Radiation and drug therapies, and leukemia.
Topics: Antineoplastic Agents; Benzene; Bone Marrow Diseases; Chloramphenicol; Cyclophosphamide; Dose-Respon | 1973 |
[Leukemia origin after benzene and phenylbutazone].
Topics: Adult; Benzene; Humans; Leukemia; Male; Middle Aged; Occupational Diseases; Phenylbutazone | 1973 |
[Oluprine and hematopoiesis].
Topics: Acetaminophen; Adult; Aged; Anemia, Hemolytic; Bone Marrow Diseases; Female; Hematopoiesis; Humans; | 1971 |
Phenylbutazone and leukaemia.
Topics: Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Joint Diseases; Leukemia; Leuk | 1965 |
Phenylbutazone and leukaemia. Is there a relationship?
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Chronic Disease; Female; Humans; Leukemia; Male | 1969 |
[Pancytopenia associated with total situs inversus (Fanconi's syndrome in adults)].
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Chronic Disease; Fanconi Syndrome; Humans; Leukemia; | 1969 |
[Phenylbutazone, adjuvant in treatment of malignant hemopathy and especially Hodgkin's disease].
Topics: Adult; Aged; Child; Female; Hodgkin Disease; Humans; Leukemia; Male; Phenylbutazone; Sarcoma | 1969 |
Leukemia and ankylosing spondylitis.
Topics: Humans; Leukemia; Phenylbutazone; Spondylitis, Ankylosing | 1970 |
Leukemia and ankylosing spondylitis.
Topics: Humans; Leukemia; Phenylbutazone; Spondylitis, Ankylosing | 1970 |
[Idiopathic and drug-induced acquired aplastic anemia].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Androgens; Anemia, Aplastic; Blood Transfusion; Chloramp | 1970 |
Phenylbutazone and acute leukemia.
Topics: Adult; Aged; Humans; Leukemia; Middle Aged; Phenylbutazone | 1966 |