phenylbutazone has been researched along with Kidney Papillary Necrosis in 18 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Kidney Papillary Necrosis: A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A decrease in total blood neutrophil count occurred in all horses, and was associated with toxic left shift in horses given the 2 larger dosage schedules." | 1.27 | Effects of large doses of phenylbutazone administration to horses. ( French, TW; MacKay, RJ; Mayhew, IG; Nguyen, HT, 1983) |
| "Three patients with ankylosing spondylitis developed renal papillary necrosis." | 1.26 | Association of renal papillary necrosis and ankylosing spondylitis. ( Denman, SJ; Lourie, SH; Schroeder, ET, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (94.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clive, DM | 1 |
| Stoff, JS | 1 |
| Faulkner, LW | 1 |
| Erb, HN | 1 |
| King, JM | 1 |
| Gunson, DE | 2 |
| Soma, LR | 1 |
| Read, WK | 1 |
| MacKay, RJ | 1 |
| French, TW | 1 |
| Nguyen, HT | 1 |
| Mayhew, IG | 1 |
| Jackson, B | 1 |
| Lawrence, JR | 1 |
| Lourie, SH | 1 |
| Denman, SJ | 1 |
| Schroeder, ET | 1 |
| Ferguson, I | 1 |
| Johnson, F | 1 |
| Reay, B | 1 |
| Wigley, R | 1 |
| Arnold, L | 2 |
| Collins, C | 2 |
| Starmer, GA | 2 |
| Wigley, RA | 1 |
| Segasothy, M | 1 |
| Samad, S | 1 |
| Carlton, WW | 1 |
| Engelhardt, JA | 1 |
| Owen, RA | 1 |
| Heywood, R | 1 |
| Davies, DJ | 1 |
| Kennedy, A | 1 |
| Roberts, C | 1 |
| Morales, A | 1 |
| Steyn, J | 1 |
| Lawson, AA | 1 |
| Maclean, N | 1 |
1 review available for phenylbutazone and Kidney Papillary Necrosis
| Article | Year |
|---|---|
Renal syndromes associated with nonsteroidal antiinflammatory drugs.
Topics: Acute Kidney Injury; Adult; Animals; Anti-Inflammatory Agents; Anuria; Aspirin; Body Water; Electrol | 1984 |
17 other studies available for phenylbutazone and Kidney Papillary Necrosis
| Article | Year |
|---|---|
Renal papillary necrosis in equines.
Topics: Animals; Clonixin; Horse Diseases; Horses; Kidney Papillary Necrosis; Nicotinic Acids; Phenylbutazon | 1984 |
Renal papillary necrosis in horses.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clonixin; Dehyd | 1983 |
Renal papillary necrosis in horses after phenylbutazone and water deprivation.
Topics: Animals; Horse Diseases; Horses; Kidney; Kidney Papillary Necrosis; Phenylbutazone; Time Factors; Wa | 1983 |
Renal medullary crest necrosis associated with phenylbutazone therapy in horses.
Topics: Animals; Female; Horse Diseases; Horses; Kidney Medulla; Kidney Papillary Necrosis; Male; Phenylbuta | 1983 |
Effects of large doses of phenylbutazone administration to horses.
Topics: Animals; Anti-Inflammatory Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Gastric Mucosa; G | 1983 |
Renal papillary necrosis associated with indomethacin and phenylbutazone treated rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Indomethacin; Kidney Papillary Necrosis; Male; Middle Aged; Phenylbut | 1978 |
Association of renal papillary necrosis and ankylosing spondylitis.
Topics: Adult; Humans; Ibuprofen; Indomethacin; Kidney Papillary Necrosis; Male; Phenylbutazone; Spondylitis | 1977 |
Aspirin, phenacetin, and the kidney: a rheumatism clinic study.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Australia; Drug Combinations; Humans; Kidney Papillary Necros | 1977 |
Further studies of the acute effects of phenylbutazone, oxyphenbutazone and indomethacin on the rat kidney.
Topics: Acute Disease; Animals; Calcinosis; Female; Indomethacin; Kidney Cortex; Kidney Cortex Necrosis; Kid | 1976 |
The New Zealand experience.
Topics: Aspirin; Drug Combinations; Drug Synergism; Humans; Kidney Papillary Necrosis; New Zealand; Phenacet | 1976 |
Illicit herbal preparation containing phenylbutazone causing analgesic nephropathy.
Topics: Aged; Drug Contamination; Female; Humans; Kidney Papillary Necrosis; Phenylbutazone; Plants, Medicin | 1991 |
Experimental renal papillary necrosis in the Syrian hamster.
Topics: Acetaminophen; Animals; Cricetinae; Disease Models, Animal; Ethylamines; Indomethacin; Kidney Medull | 1989 |
Strain-related susceptibility to nephrotoxicity induced by aspirin and phenylbutazone in rats.
Topics: Animals; Aspirin; Body Weight; Diuresis; Female; Kidney Papillary Necrosis; Male; Organ Size; Phenyl | 1986 |
Renal and gastric lesions after phenylbutazone and indomethacin in the rat.
Topics: Animals; Ascites; Epithelium; Female; Gastrointestinal Hemorrhage; Indomethacin; Kidney; Kidney Papi | 1974 |
The aetiology of renal medullary necrosis: a survey of adult cases in Liverpool.
Topics: Adult; Aged; Aspirin; Codeine; Diabetes Complications; England; Female; Humans; Kidney; Kidney Papil | 1970 |
Papillary necrosis following phenylbutazone ingestion.
Topics: Aged; Humans; Kidney Papillary Necrosis; Male; Phenylbutazone; Radiography | 1971 |
Renal disease and drug therapy in rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Female; Humans; Kidney Dis | 1966 |