phenylbutazone has been researched along with Hyperplasia in 4 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Uncommon tubular cell tumors of the kidney were found in 13 exposed rats: 5 in the 50 mg group and 4 in the 100 mg group of males; 4 in dosed female rats; none in controls." | 1.29 | Long-term exposure to the anti-inflammatory agent phenylbutazone induces kidney tumors in rats and liver tumors in mice. ( Bucher, J; Eustis, S; Haseman, J; Huff, J; Kari, F, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kari, F | 1 |
| Bucher, J | 1 |
| Haseman, J | 1 |
| Eustis, S | 1 |
| Huff, J | 1 |
| Weirich, EG | 1 |
| Longauer, JK | 1 |
| Kirkwood, AH | 1 |
| Tan, KN | 1 |
| Medak, H | 1 |
| Cohen, L | 1 |
| Burlakow, P | 1 |
| Calandra, P | 1 |
| Ribacchi, R | 1 |
4 other studies available for phenylbutazone and Hyperplasia
| Article | Year |
|---|---|
Long-term exposure to the anti-inflammatory agent phenylbutazone induces kidney tumors in rats and liver tumors in mice.
Topics: Adenoma; Animals; Corn Oil; Female; Hyperplasia; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; M | 1995 |
Epidermal antihyperplastic effects of contact antiphlogistics.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bufexamac; Fluocinolone Acetonide; Guinea Pigs; Hydrocor | 1978 |
Focal epithelial hyperplasia in a Mexican Indian.
Topics: Azathioprine; Child; Cyclophosphamide; Epithelium; Estrogens, Conjugated (USP); Glomerulonephritis; | 1969 |
[Phenylbutazone and subacute lymphadenosis: report of a case].
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Hyperplasia; Leukemia, Lymphoid; Lymph Node | 1965 |