Page last updated: 2024-11-02

phenylbutazone and Granuloma

phenylbutazone has been researched along with Granuloma in 109 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Research Excerpts

ExcerptRelevanceReference
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."7.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)
"The sub-effective dose of VN potentiated anti-inflammatory activity of phenlbutazone and ibuprofen significantly in carrageenin induced hind paw oedema and cotton pellet granuloma models."3.73Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard anti-inflammatory drugs. ( Gupta, RK; Tandon, VR, 2006)
"The anti-inflammatory activity of Ficus racemosa extract was evaluated on carrageenin, serotonin, histamine and dextran-induced rat hind paw oedema models."3.70Anti-inflammatory evaluation of Ficus racemosa Linn. leaf extract. ( Das, J; Maity, TK; Mandal, SC; Pal, M; Saba, BP, 2000)
" In chronic models of formaldehyde and adjuvant arthritis, its anti-arthritic activity was found to be less than that of phenylbutazone (PNB)."3.69Anti-inflammatory activity of the bark of Hippocratea excelsa. ( Perez, RM; Perez, S; Salazar, M; Zavala, MA, 1995)
" The anti-inflammatory properties of FPP028 were evaluated through the carrageenan induced paw edema and the cotton pellet induced granuloma and compared with the activity of indomethacin, phenylbutazone, and isoxicam; as a result, the activity of FPP028 was shown to be similar to that of the latter compounds."3.67Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent. ( Banchelli, G; Bianchini, F; Ignesti, G; Pecori-Vettori, L; Pirisino, R; Rafanelli, D; Raimondi, L, 1986)
" Anti-edema activities of M-7074 were more potent than those of phenylbutazone in carrageenin, bradykinin and mustard edema tests in rats."3.66Anti-inflammatory properties of a newly synthesized compound, 6-chloro-4-oxyimino-1-phenyl-1,2,3,4-tetrahydroquinoline (M-7074). ( Kosuzume, H; Ohkura, M; Ohnishi, H; Satoh, M; Suzuki, Y; Toyonaka, Y; Uohama, M; Yamaguchi, K, 1981)
" The anti-inflammatory activity of Indomethacin, Oxametacine and Phenylbutazone was evaluated in these animals using paw oedema provoked by carrageenan granulomas induced by cotton pellets and polyarthritis induced by Freund complete adjuvant."3.66The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents. ( Cirillo, R; Curzio, M; Franzone, J; Sena, L; Torrielli, MV, 1981)
"Flumizole is a potent anti-inflammatory agent in animal models with an inhibitory activity severalfold that of indomethacin in rat foot edema and prostaglandin synthetase tests."3.65Flumizole, a new nonsteroidal anti-inflammatory agent. ( Bettis, JW; McIlhenny, HM; Wiseman, EH, 1975)
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."3.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)
" In a rat paw edema test for anti-inflammatory activity naproxen was 55 times more active than aspirin."3.65Chemistry and pharmacology of naproxen. ( Dorfman, RI, 1975)
" The effect was compared with the activity of hydrocortisone, phenylbutazone, sodium salicylate and cyproheptadine against different types of inflammation."3.65Inhibitory effect of a pyrrolizidine alkaloid, crotalaburnine, on rat paw oedema and cotton pellet granuloma. ( Ghosh, MN; Singh, H, 1974)
" In the granuloma pouch induced by the injection of air and croton oil, chronic administration of the drug for 7 days resulted in significant reduction in the volume of exudate and the weight of granulation tissue."1.27Effect of L-leucinamide hydrochloride on experimental inflammation. ( Al-Motrefi, A; Madan, BR, 1987)

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-1990101 (92.66)18.7374
1990's5 (4.59)18.2507
2000's3 (2.75)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Toja, E1
Selva, D2
Schiatti, P2
WINTER, CA1
RISLEY, EA1
NUSS, GW1
TRNAVSKY, K2
TRNAVSKA, Z1
MALINSKY, J1
CREPAX, P1
SILVESTRINI, B2
BENZI, G3
FRIGO, GM3
TEOTINO, UM1
FRIZ, LP1
GANDINI, A1
DELLABELLA, D1
RADOUCO-THOMAS, S1
GRUMBACH, P1
NOSAL, G1
RADOUCO-THOMAS, C1
LISIN, N1
Hewes, CA1
Schneider, RK1
Baszler, TV1
Oaks, JL1
Tandon, VR1
Gupta, RK1
Winder, CV1
Schönhöfer, P1
Anspach, KF1
Coyne, WE1
Cusic, JW1
Lisciani, R1
Barcellona, PS1
Birnie, JH2
Sutton, BM2
Zuccarello, M1
Rush, JA1
Capasso, F1
Mascolo, N1
Autore, G1
De Simone, F1
Senatore, F1
Basile, AC1
Hanada, S1
Sertié, JA1
Oga, S2
Bluth, R1
Wright, R1
Ohnishi, H1
Kosuzume, H1
Yamaguchi, K1
Ohkura, M1
Satoh, M1
Uohama, M1
Toyonaka, Y1
Suzuki, Y1
Sena, L1
Torrielli, MV1
Franzone, J1
Curzio, M1
Cirillo, R1
Boyle, E1
Mangan, FR1
Perez, RM1
Perez, S1
Zavala, MA1
Salazar, M1
Zelenin, KN1
Bezhan, IP1
Pastushenkov, LV1
Gromova, EG1
Lesiovskaja, EE1
Chakchir, BA1
Melnikova, LF1
Mandal, SC1
Maity, TK1
Das, J1
Saba, BP1
Pal, M1
Cashin, CH1
Dawson, W1
Kitchen, EA1
Vogel, HG1
Koshihara, Y1
Yamagishi, M1
Murota, SI1
Beascoa, E1
Giráldez, A1
Llenas, J1
Zapatero, J1
Bruseghini, L1
Wiseman, EH2
McIlhenny, HM1
Bettis, JW1
Ishak, KG1
Kirchner, JP1
Dhar, JK1
Kulonen, E1
Potila, M1
Dorfman, RI1
Fanelli, O1
Nakamura, H1
Shimizu, M1
Anker, N1
Skovbjerg, H1
Grau, M1
Guasch, J1
Montero, JL1
Felipe, A1
Carrasco, E1
Juliá, S1
Frechilla, D1
Lasheras, B1
Ucelay, M1
Parrondo, E1
Craciunescu, G1
Cenarruzabeitia, E1
Oshiro, TT1
Teixeira, CF1
Begum, VH1
Sadique, J1
Madan, BR1
Al-Motrefi, A1
Altmann, HW1
Pirisino, R1
Bianchini, F1
Banchelli, G1
Ignesti, G1
Raimondi, L1
Pecori-Vettori, L1
Rafanelli, D1
Tsuji, H1
Kalyanpur, SG1
Pohujani, S1
Naik, SR3
Sheth, UK3
Holmes, B1
Good, RA1
Chiku, S1
Okada, M1
Mori, Y1
Ono, T1
Tsurufuji, S3
Mörsdorf, K1
Anspach, K1
Stancikova, M1
Julou, L1
Guyonnet, JC1
Ducrot, R1
Bardone, MC1
Detaille, JY1
Laffargue, B1
Eichler, O1
Koch, C1
Tubaro, E1
Banci, F1
Kawai, K1
Kuzuna, S1
Morimoto, S1
Ishii, H1
Matsumoto, N1
Lombardino, JG1
Ghosh, MN1
Singh, H1
Fujimura, H3
Tsurumi, K5
Go, K2
Hiramatsu, Y3
Tamura, Y1
Márquez, M1
Roberts, DJ1
Navarro, J1
Stoliaroff, M1
Savy, JM1
Berny, C1
Brunaud, M1
Arrigoni-Martelli, E1
Lerner, LJ1
Diena, A1
Sardi, A1
Maffii, G1
Komatsu, T2
Awata, H3
Sakai, Y2
Inukai, T2
Kimura, M1
Inaba, S3
Yamamoto, H3
Roszkowski, AP2
Rooks, W1
Tomolonis, A1
Miller, L1
Pelczarska, AB1
Gupta, SK1
Sharma, RC1
Aggarwal, OP1
Arora, RB1
Yamamoto, M2
Kaplinsky, N1
Schwartz, J1
Frankl, O1
DiPasquale, G1
Rassaert, C1
Richter, R1
Welaj, P1
Tripp, L1
Nozaki, M2
Hayashi, M4
Nakano, K1
Nannini, G1
Giraldi, PN1
Molgora, G1
Biasoli, G1
Spinelli, F1
Logemann, W1
Dradi, E1
Zanni, G1
Buttinoni, A2
Tommasini, R2
Cuttica, A1
Franceschini, J1
Mandelli, V1
Orsini, G1
Passerini, N1
Turba, C2
Riedel, R1
Schoetensack, W1
Saito, C1
Caprino, L1
Borrelli, F1
Falchetti, R1
Yamaguchi, A2
Shibuya, T1
Abe, A1
Wiesinger, D1
Gubler, HU1
Haefliger, W1
Hauser, D1
Warawa, EJ1
Mueller, NJ1
Jules, R1
Kalyanpur, S1
Tanaka, K1
Iizuka, Y1
Bianchi, C1
Lumachi, B1
Marazzi-Uberti, E2
Mielens, ZE1
Rooks, WH1
Tomolonis, AJ1
Miller, LM1
Swingle, KF1
Hamilton, RR1
Harrington, JK1
Kvam, DC1
Guhlke, I1
Schmidt, J1
Carson, JR1
McKinstry, DN1
Wong, S1
Akimoto, T1
Tsukada, W1
Yamasaki, T1
Kojima, H1
Kasahara, A1
Fukuhara, M2
Szirmai, E2
Airò, R1
Nakanishi, M2
Imamura, H2
Maruyama, Y2
Lambelin, G1
Vassart-Thys, D1
Roba, J1
Rupawalla, EN1
Ito, M1
Di Rosa, M1
Barron, DI1
Copley, AR1
Vallance, DK1
Adam, M1
Weissová, J1
Steinbrocker, O1
Paltauf, R1
Celander, DR1
Medgyesi, G1
Jakovlev, V1
von Schlichtegroll, A1
Jahn, U1
Adrian, RW1
Dave, CV1
Couto, FF1
Ambike, SH1
Lowrie, HS3

Reviews

2 reviews available for phenylbutazone and Granuloma

ArticleYear
Drug-induced chronic hepatitis.
    Springer seminars in immunopathology, 1980, Volume: 3, Issue:3

    Topics: Allopurinol; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Female; Granuloma

1980
Pharmacological properties of naproxen.
    Scandinavian journal of rheumatology. Supplement, 1973, Volume: 2

    Topics: Administration, Oral; Administration, Topical; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory A

1973

Other Studies

107 other studies available for phenylbutazone and Granuloma

ArticleYear
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclini

1984
ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITIES OF INDOMETHACIN, 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Acetates; Adrenalectomy; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents

1963
[EFFECT OF PHENYLBUTAZONE ON BIOCHEMICAL CHANGES IN EXPERIMENTAL GRANULOMA].
    Casopis lekaru ceskych, 1964, May-15, Volume: 103

    Topics: DNA; Exudates and Transudates; Granuloma; Hexosamines; Hydroxyproline; Pharmacology; Phenylbutazone;

1964
EXPERIMENTAL EVALUATION IN LABORATORY ANIMALS OF ANTI-INFLAMMATORY ANALGESIC DRUGS.
    Archives italiennes de biologie, 1963, Oct-05, Volume: 101

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Animals, Laboratory; Anti-Inflammatory A

1963
[INTERFERENCE OF SOME FACTORS IN THE COTTON PELLET GRANULOMA TEST].
    Il Farmaco; edizione pratica, 1964, Volume: 19

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cotton Fiber; Drug Industry; Granuloma; Hydrocor

1964
[EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF SOME DRUGS BY PAW EDEMA TESTS AND COTTON PELLET GRANULOMA IN RATS].
    Il Farmaco; edizione pratica, 1964, Volume: 19

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Edema; Formaldehyde; Granuloma; Indoles; Inflamma

1964
THIO DERIVATIVES OF 2,3-DIHYDRO-4H-1,3-BENZOXAZIN-4-ONE. SYNTHESIS AND PHARMACOLOGICAL PROPERTIES.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Ascites; Aspirin; Chem

1963
ANTI-INFLAMMATORY EFFECT OF TRIHYDROXYETHYLRUTOSIDE.
    Life sciences (1962), 1964, Volume: 3

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Aspirin; Flavonoids; G

1964
[CONTRIBUTION TO THE EXPERIMENTAL STUDY OF A NEW ANTI-INFLAMMATORY AGENT, "A-230"].
    Archives internationales de pharmacodynamie et de therapie, 1964, Oct-01, Volume: 151

    Topics: 17-Hydroxycorticosteroids; Abscess; Adrenal Glands; Adrenalectomy; Analgesics; Analgesics, Non-Narco

1964
Septic arthritis and granulomatous synovitis caused by infection with Mycobacterium avium complex in a horse.
    Journal of the American Veterinary Medical Association, 2005, Jun-15, Volume: 226, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Diagnosis, Differential; Gr

2005
Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard anti-inflammatory drugs.
    The Indian journal of medical research, 2006, Volume: 124, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Edema; Female; Granuloma;

2006
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. I. Pharmacology.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Chemistry, Physical; E

1966
[The activity of L-glutamine-D-fructose-6-phosphate aminotransferase in the course of a carrageenan induced inflammation and its inhibition by phenylbutazone].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 166, Issue:2

    Topics: Animals; Carrageenan; Female; Granuloma; In Vitro Techniques; Liver; Phenylbutazone; Rats; Transamin

1967
Antiinflammatory dialkylaminoalkylureas.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:4

    Topics: Animals; Biological Assay; Candida; Chemistry, Organic; Edema; Granuloma; Male; Organic Chemistry Ph

1967
Anti-granuloma and thymolytic activity of certain drugs.
    European journal of pharmacology, 1967, Volume: 1, Issue:3

    Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Body Weight; Chlorpromazine; Cortisone; Female; G

1967
Some anti-inflammatory properties of 8-trifluoromethylphenothiazine-1-carboxylic acid (SK & F 22908).
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:1

    Topics: Animals; Erythema; Flufenamic Acid; Granuloma; Guinea Pigs; Indomethacin; Male; Phenothiazines; Phen

1967
Anti-inflammatory and analgesic activity in alcoholic extract of Tamus communis L.
    Journal of ethnopharmacology, 1983, Volume: 8, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Granuloma; Lethal Dose 50; Male; Phen

1983
Anti-inflammatory effects of praseodymium, gadolinium and ytterbium chlorides.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Chlorides; Disease Models, Ani

1984
[Comparison of the effect of 3-amino-4-mercapto-6-methylpyridazine with various antiphlogistic agents in rat models of inflammation].
    Die Pharmazie, 1982, Volume: 37, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Di

1982
Anti-inflammatory properties of a newly synthesized compound, 6-chloro-4-oxyimino-1-phenyl-1,2,3,4-tetrahydroquinoline (M-7074).
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:5

    Topics: Aminoquinolines; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroi

1981
The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents.
    The Journal of pathology, 1981, Volume: 135, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema;

1981
The histology and collagen content of cotton pellet and polyvinyl sponge-induced granulomas in normal and drug-treated rats.
    British journal of experimental pathology, 1980, Volume: 61, Issue:4

    Topics: Aminopropionitrile; Animals; Collagen; Dexamethasone; DNA; Female; Gossypium; Granuloma; Indomethaci

1980
Anti-inflammatory activity of the bark of Hippocratea excelsa.
    Journal of ethnopharmacology, 1995, Jul-07, Volume: 47, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1995
Anti-inflammatory activity of 2-acyl-5(3)-hydroxytetrahydro-1H-pyrazole derivatives.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Carrageenan; Edema; Epinephrine;

1999
Anti-inflammatory evaluation of Ficus racemosa Linn. leaf extract.
    Journal of ethnopharmacology, 2000, Volume: 72, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dextrans; Edema; Foot; Granuloma; His

2000
The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Arthritis, Experimental; Benzoxazo

1977
Mechanical and chemical properties of various connective tissue organs in rats as influenced by non-steroidal antirheumatic drugs.
    Connective tissue research, 1977, Volume: 5, Issue:2

    Topics: Animals; Aspirin; Biomechanical Phenomena; Bone and Bones; Cartilage; Collagen; Connective Tissue; G

1977
Effect of salicyclic acid on gluccorticoid receptor in cultured fibroblasts derived from rat carrageenin granuloma.
    Biochimica et biophysica acta, 1976, Jun-23, Volume: 437, Issue:1

    Topics: Animals; Carrageenan; Cell Line; Cycloheximide; Cytosol; Dexamethasone; Fibroblasts; Granuloma; Indo

1976
[Pharmacology of a new derivative with anti-inflammatory activity: ITA 194].
    Archivos de farmacologia y toxicologia, 1978, Volume: 4, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dogs; Feprazone; Gastric Muco

1978
Flumizole, a new nonsteroidal anti-inflammatory agent.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:9

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Availability; Cyclooxygenase Inh

1975
Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:7

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Cholestasis; Diazepam; Granuloma; Hu

1977
Effect of the administration of antirheumatic drugs on experimental granuloma in rat.
    Biochemical pharmacology, 1975, Jan-15, Volume: 24, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cellulose; Cytidine; Granuloma; Hexosamines; Hydroxyprol

1975
Chemistry and pharmacology of naproxen.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2A

    Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Ed

1975
Some pharmacological properties of 2-aryl-1,3-indandione derivatives.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticoagulants; Antitussive Agents; Drug Evaluation,

1975
Effect of anti-inflammatory agents on accelerated granuloma formation in rats.
    Chemical & pharmaceutical bulletin, 1975, Volume: 23, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Flufenamic Acid; Granuloma; Indomethacin;

1975
[Granulomatous liver disease induced by phenylbutazone].
    Ugeskrift for laeger, 1975, Dec-15, Volume: 137, Issue:51

    Topics: Chemical and Drug Induced Liver Injury; Female; Granuloma; Humans; Middle Aged; Phenylbutazone

1975
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary

1991
Anti-inflammatory activity of some copper(II) complexes.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

1990
Propylene glycol enhances anti-inflammatory effects of phenylbutazone.
    General pharmacology, 1990, Volume: 21, Issue:1

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Carrageenan

1990
Effect of Withania somnifera on glycosaminoglycan synthesis in carrageenin-induced air pouch granuloma.
    Biochemical medicine and metabolic biology, 1987, Volume: 38, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Blood Cell Count; Carrageenan; Glycosaminoglycans; Granuloma; Hy

1987
Effect of L-leucinamide hydrochloride on experimental inflammation.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 58, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Female; Granuloma; Leucine; Male; Organ Siz

1987
Morphological changes in the liver due to phenazone and its derivatives.
    Agents and actions. Supplements, 1986, Volume: 19

    Topics: Antipyrine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Fatty Liver; Granulom

1986
Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent.
    Pharmacological research communications, 1986, Volume: 18, Issue:3

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1986
[Anti-inflammatory principle synthesized by a strain of Serratia sp].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, May-20, Volume: 65, Issue:3

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Bromelains; Carrageenan; Chymotrypsin; Ed

1969
Study of biochemical effects of anti-inflammatory drugs in carrageenin induced oedema and cotton pellet granuloma.
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Adenosine Triphosphatases; Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain; Edema;

1968
Laboratory models of chronic granulomatous disease.
    Journal of the Reticuloendothelial Society, 1972, Volume: 12, Issue:2

    Topics: Amobarbital; Animals; Blood Bactericidal Activity; Chronic Disease; Dehydroepiandrosterone; Dihydrol

1972
[Changes in glycosaminoglycans and glycoproteins during development of proliferative inflamed tissue and effect of anti-inflammatory drugs on the metabolism of these hexosamine-containing substances (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1974, Volume: 94, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Carrageenan; Chondroitin; Glycoproteins; Glycosami

1974
The mode of action of hydrocortisone on the protein metabolism in rat carrageenin granuloma.
    Biochemical pharmacology, 1970, Volume: 19, Issue:1

    Topics: Animals; Betamethasone; Carrageenan; Cycloheximide; Granuloma; Hydrocortisone; In Vitro Techniques;

1970
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D

1971
Effects of phenylbutazone on the activities of cathepsin D, collagenolytic cathepsin and collagen peptidase in turpentine-induced granuloma.
    Pathologie-biologie, 1974, Volume: 22, Issue:8

    Topics: Animals; Cathepsins; Collagen; Granuloma; Microbial Collagenase; Phenylbutazone; Rats; Turpentine

1974
[General pharmacological properties of methiazinic acid (16091 RP)].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Abscess; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Autonomic Nervous Syste

1969
[Antiphlogistic, analgesic and spasmolytic effect of harpagoside, a glycoside from the root of Harpagophytum procumbens DC].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:1

    Topics: Acetylcholine; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Atropine; Croton Oil; Depre

1970
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101).
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageena

1970
Anti-inflammatory, analgesic and antipyretic activities of 6-chloro-5-cyclohexylindan-1-carboxylic acid (TAI-284).
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Bronchodilator Agents; Capillary Permeabil

1971
Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:11

    Topics: Administration, Oral; Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Carrageenan;

1974
Inhibitory effect of a pyrrolizidine alkaloid, crotalaburnine, on rat paw oedema and cotton pellet granuloma.
    British journal of pharmacology, 1974, Volume: 51, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Animals; Arthritis; Bradykinin; Carrageenan; Dextrans; Edema; Formald

1974
[Pharmacological study of phthalazino-(2,3-b)-phthalazine-5 (14H), 12(7H)-dione (L-5418)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:3

    Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Barbiturates; Blood Co

1974
Pharmacological properties of thiazolinobutazone (LAS 11871). I. Anti-inflammatory effects.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:11

    Topics: Abscess; Administration, Oral; Adrenalectomy; Animals; Bradykinin; Bronchial Spasm; Carrageenan; Ede

1974
[Pharmacologic properties of a new, nonsteroidal anti-inflammatory agent, bucloxic acid (804 CB)].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:9A SUPPL

    Topics: Administration, Oral; Adrenal Glands; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Cycl

1974
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Ev

1974
Synthesis and pharmacology of a novel anti-inflammatory agent, ID-1619.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Chemical Phenomena

1972
Anti-inflammatory activity of the oil isolated from Cyperus scariosus (R. Br.).
    Indian journal of experimental biology, 1972, Volume: 10, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Edema; Granuloma; Hydrocortisone; Inflamm

1972
Novel quinazoline derivatives. I. Synthesis and preliminary pharmacological evaluation of an anti-inflammatory agent, SL-573.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:11

    Topics: Administration, Oral; Analgesics; Animals; Anisoles; Anti-Inflammatory Agents; Arthritis; Capillary

1972
[Löfgren syndrome].
    Harefuah, 1973, May-01, Volume: 84, Issue:9

    Topics: Adult; Ankle Joint; Arthritis; Erythema Nodosum; Granuloma; Humans; Liver Diseases; Periarthritis; P

1973
Influence of prostaglandins (Pg) E2 and F2 on the inflammatory process.
    Prostaglandins, 1973, Volume: 3, Issue:6

    Topics: Animals; Arthritis; Aspirin; Carrageenan; Croton Oil; Edema; Foot; Granuloma; Hindlimb; Hydrocortiso

1973
[Pharmacological studies on N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F-1). 1. Anti-inflammatory action].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5

    Topics: Adrenal Glands; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Ascorbic Acid; Aspirin; B

1973
New analgesic-anti-inflammatory drugs. 1-Oxo-2-substituted isoindoline derivatives.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Drug Evaluation, Preclinical; Edema; Gra

1973
Pharmacological study on a new analgesic-anti-inflammatory drug: alpha-(4-(1-oxo-2-iso-indolinyl)-phenyl)-propionic acid of K 4277.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:8

    Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Behavi

1973
[Pharmacology of butylmalonic acidmono-(1,2-diphenylhydrazide)-calcium (bumadizone-calcium)].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Blood Pr

1973
Novel quinazoline derivatives. II. A new anti-inflammatory agent, SL-512.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; Cyclopropanes; Ede

1973
Pharmacological research on 4,5-diphenyl-2-bis(2-hydroxyethyl)-aminoxazol (Ditazol), a new synthetic oxazole derivative as an anti-inflammatory agent.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Administration, Oral; Administration, Topical; Adrenalectomy; Analgesics; Animals; Anti-Inflammatory

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 2. On subacute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Body Weight; Ed

1973
[Anti-inflammatory and analgesic effects of benzodiazepine derivatives].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzazepines; Capillary Permeability; Chlorpromazine;

1973
Antiinflammatory activity of the new mould metabolite 11-desacetoxy-wortmannin and of some of its derivatives.
    Experientia, 1974, Feb-15, Volume: 30, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Coumarins; Dexamethasone; Edema; Freund's

1974
Quinuclidine chemistry. 2. Synthesis and antiinflammatory properties of 2-substituted benzhydryl-3-quinuclidinols.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:5

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Benzene Derivatives; Carrageenan; Edema; Granuloma

1974
Effects of anti-inflammatory drugs on glutathione levels and liver succinic dehydrogenase activity in carrageenin edema and cotton pellet granuloma in rats.
    Biochemical pharmacology, 1972, Feb-15, Volume: 21, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Glutathione; Gossypium; Granuloma; Hydrocorti

1972
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid;

1972
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 1. Anti-inflammatory, analgesic and antipyretic properties.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Erythema; F

1972
Response of "acute phase" globulins in different models of inflammation in rats.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, May-01, Volume: 10, Issue:9

    Topics: Acute Disease; Adjuvants, Immunologic; Animals; Arthritis; Aspirin; Disease Models, Animal; Granulom

1971
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Fe

1971
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Car

1971
[A comparative study on various antiphlogistics].
    Acta biologica et medica Germanica, 1971, Volume: 26, Issue:2

    Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Asbestos; Dextrans; Disease Models, Animal; Dr

1971
5-Benzoyl-1-methylpyrrole-2-acetic acids as antiinflammatory agents.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:17

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Benzoates; Carrageenan; Edema; Granuloma; Indomethacin;

1971
[Pharmacological studies of calcium-N-n-butylmalonic acid-N,N'-diphenylhydrazide (B-64114-Ca). 1. Anti-inflammatory effects].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:4

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Calcium; Capillary Permeability; Carrag

1971
[Pharmacological studies on 1-(4-methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole (DA-398), a new anti-inflammatory agent].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Jul-20, Volume: 65, Issue:4

    Topics: Adrenal Glands; Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antitussive Agents; Anur

1969
The effect of locally injected anti-inflammatory drugs on the synthesis of collagen and non-collagen protein of carrageenin granuloma in rats.
    Biochemical pharmacology, 1969, Volume: 18, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Body Weight; Carrageenan; Collagen; Granuloma; Hyd

1969
[Effect of Vasotonin-forte on the formation of Selye's granuloma and on the local complications of varicose syndromes].
    Minerva medica, 1970, Jun-02, Volume: 61, Issue:44

    Topics: Animals; Epinephrine; Granuloma; Humans; Phenylbutazone; Radiation Injuries; Rats; Skin Diseases; Va

1970
[Studies on anti-inflammatory agents. 3. Effect of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine (Y-3642) on pyretic reaction, vascular permeability and granuloma formation in experimental animals].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1970, Volume: 90, Issue:3

    Topics: Adrenalectomy; Aminopyrine; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Fever;

1970
Pharmacological studies of Bufexamac topically applied on the skin.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 187, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Carrageenan; Edema; Erythema; Female; Fluocinolone

1970
Anti-inflammatory activity of thiamine and nicotinic acid.
    Biochemical pharmacology, 1970, Volume: 19, Issue:11

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Calcium; Carra

1970
[Influence of various drugs on the tissue permeability. 5. Comparison of the potency of various anti-inflammatory agents by the dermal tissue permeability test using filter paper implanted subcutaneously in the ventral region of rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Volume: 66, Issue:6

    Topics: Administration, Oral; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Azepines; Bromelains;

1970
Pharmacological investigations of 2-amino-3-ethoxy-carbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Bradykinin; C

1970
Pharmacological studies on ethyl-3,5,6-tri-O-benzyl-D-glucofuranoside (CIBA 21,401-BA).
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Croton Oil; Edema; Exudates and Transuda

1968
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial

1968
[Effect of sodium aurothiosulfate on the formation of collagen].
    Fysiatricky a reumatologicky vestnik, 1968, Volume: 46, Issue:2

    Topics: Animals; Carbon Isotopes; Carrageenan; Collagen; Gold; Granuloma; Male; Microscopy, Electron; Phenyl

1968
Inhibitory effects on granuloma of the Selye (pouch) type in rats by administration of T-1824 (Evans blue).
    Experimental medicine and surgery, 1968, Volume: 26, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Coloring Agents; Connective Tissue; Exudates and Transudates; Fem

1968
The effect of locally injected anti-inflammatory drugs on the carrageenin granuloma in rats.
    Biochemical pharmacology, 1969, Volume: 18, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Body Weight; Carrageenan; Collagen; Diet; Granulom

1969
[Studies of the inflammation inhibitory effect of monophenylbutazone as well as a contained active combination by Selye].
    Die Pharmazie, 1969, Volume: 24, Issue:6

    Topics: Analgesics; Animals; Croton Oil; Exudates and Transudates; Granuloma; Inflammation; Male; Phenylbuta

1969
[On the inflammation inhibitory effect of (-)-alpha-bisabolol, an essential component of chamomilla oil].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cycloparaffins; Edema; Female; Granuloma; Indomethac

1969
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo

1969
[Action of formalin on the cotton pellet granuloma test].
    Bollettino della Societa italiana di biologia sperimentale, 1964, Jun-15, Volume: 40, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Formaldehyde; Gossypium; Granuloma; Indomethacin; Inflammation; M

1964
Studies of hamycin on inflammation and related mechanism.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 122, Issue:1

    Topics: Adrenal Glands; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Body Weight; Formaldehyde;

1966
Alpha-Isopropyl-alpha-(2-dimethylaminoethyl)-1-naphthylacetamide (naphthypramide, DA 992): a new anti-inflammatory agent. I. Antiinflammatory activity and acute toxicity.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 162, Issue:2

    Topics: Agar; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Dextrans; Edema; Forma

1966
3-phenylcinnolines. II. The preparation of 4-amino derivatives.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Chemistry, Organic; Dicarboxylic Acids; Diuresis;

1966
3-phenylcinnolines. I. Some reactions and derivatives of 3-phenylcinnoline-4-carboxylic acids.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:5

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Blood Pressure; Chemistry, Organic; Dicarboxylic A

1966
3-phenylcinnolines. 3. Derivatives of hydroxy-3-phenylcinnolines.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:5

    Topics: Animals; Chemistry, Organic; Diuresis; Edema; Granuloma; Heterocyclic Compounds; Hydrochlorothiazide

1966
Phenothiazine-1-carboxylic acids.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Chemistry, Organic; Dicarboxylic Acids; Erythema;

1966