phenylbutazone has been researched along with Gait Disorders, Animal in 26 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis." | 9.13 | Comparison of efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis. ( Alva, R; Bertone, AL; Doucet, MY; Hanson, PD; Hendrickson, D; Hughes, F; Kunkle, B; Macallister, C; McClure, S; Reinemeyer, C; Romano, D; Rossier, Y; Sifferman, R; Vrins, AA; White, G, 2008) |
| "The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours." | 9.08 | Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996) |
| "In horses with navicular syndrome treated once daily for 4 days, typical clinical doses of flunixin and phenylbutazone resulted in similar significant improvement in lameness at 6, 12, and 24 hours after the final dose, compared with findings in horses treated with saline solution." | 7.73 | Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome. ( Clarke, CR; Erkert, RS; MacAllister, CG; Payton, ME, 2005) |
| "Ketorolac tromethamine was not superior to FM or PB in reducing lameness using a HBS model." | 6.94 | Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses. ( Brunner, TJ; Cooper, BR; Davern, AJ; Grady, SE; Lescun, TB; Moore, GE; Taylor, SD, 2020) |
| " These data suggest that ketoprofen at the dosage rate of 1." | 5.29 | Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. ( Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR, 1995) |
| "To compare efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis." | 5.13 | Comparison of efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis. ( Alva, R; Bertone, AL; Doucet, MY; Hanson, PD; Hendrickson, D; Hughes, F; Kunkle, B; Macallister, C; McClure, S; Reinemeyer, C; Romano, D; Rossier, Y; Sifferman, R; Vrins, AA; White, G, 2008) |
| "The objective was to test the hypothesis that phenylbutazone (PBZ) alleviates lameness in an adjustable heart bar shoe model of equine foot pain." | 5.13 | Effects of single-dose intravenous phenylbutazone on experimentally induced, reversible lameness in the horse. ( Barange, A; Foreman, JH; Hungerford, LL; Lawrence, LM, 2008) |
| "The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours." | 5.08 | Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996) |
| "Using an adjustable heart bar shoe model of foot pain, the objective of this study was to test the hypothesis that the combined use of phenylbutazone (PBZ) and flunixin meglumine (FM) would prove more efficacious in alleviating lameness than either drug alone." | 3.77 | Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses. ( Foreman, JH; Ruemmler, R, 2011) |
| "In horses with navicular syndrome treated once daily for 4 days, typical clinical doses of flunixin and phenylbutazone resulted in similar significant improvement in lameness at 6, 12, and 24 hours after the final dose, compared with findings in horses treated with saline solution." | 3.73 | Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome. ( Clarke, CR; Erkert, RS; MacAllister, CG; Payton, ME, 2005) |
| "Ketorolac tromethamine was not superior to FM or PB in reducing lameness using a HBS model." | 2.94 | Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses. ( Brunner, TJ; Cooper, BR; Davern, AJ; Grady, SE; Lescun, TB; Moore, GE; Taylor, SD, 2020) |
| "Phenylbutazone paste was administered at approximately 2." | 2.73 | Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses. ( Keegan, KG; Kramer, J; Messer, NT; Reed, SK; Wilson, DA, 2008) |
| "To compare analgesic effects of phenylbutazone administered at a dosage of 4." | 2.71 | Evaluation of the analgesic effects of phenylbutazone administered at a high or low dosage in horses with chronic lameness. ( Erkert, RS; Hu, HH; MacAllister, CG; Payton, ME, 2005) |
| "Phenylbutazone was administered as before, and PVGRF was measured." | 2.71 | Quantitative comparison of three commonly used treatments for navicular syndrome in horses. ( Blaik, MA; Jann, HW; Schoonover, MJ, 2005) |
| "The therapy was repeated following recurrence of the lameness." | 1.30 | [Navicular disease in the hind limb of a Warmblood horse]. ( Meijer, MC; Rijkenhuizen, AB, 1999) |
| " These data suggest that ketoprofen at the dosage rate of 1." | 1.29 | Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. ( Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR, 1995) |
| "oral phenylbutazone treatment over the next 3 years allowed the stallion to continue its show career." | 1.28 | Arthroscopic removal of a palmar radial osteochondroma causing carpal canal syndrome in a horse. ( Adams, SB; Coatney, RW; Habig, C; Squire, KR; Widmer, WR, 1992) |
| "Phenylbutazone was given orally to 2 groups of horses and the plasma levels of the drug and its 2 principal metabolites oxyphenbutazone and gamma-hydroxyphenylbutazone measured by high performance liquid chromatography." | 1.26 | Pharmacokinetics of phenylbutazone and its metabolites in the horse. ( Gerring, EL; Lees, P; Taylor, JB, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Grady, SE | 1 |
| Lescun, TB | 1 |
| Moore, GE | 1 |
| Cooper, BR | 1 |
| Davern, AJ | 1 |
| Brunner, TJ | 1 |
| Taylor, SD | 1 |
| Dabareiner, RM | 1 |
| Chaffin, MK | 1 |
| Quirham, H | 1 |
| Carter, GK | 1 |
| Banse, H | 1 |
| Cribb, AE | 1 |
| Sabaté, D | 1 |
| Homedes, J | 1 |
| Salichs, M | 1 |
| Sust, M | 1 |
| Monreal, L | 1 |
| Foreman, JH | 4 |
| Grubb, TL | 1 |
| Inoue, OJ | 1 |
| Banner, SE | 1 |
| Ball, KT | 1 |
| Ruemmler, R | 1 |
| van Loon, JP | 1 |
| de Grauw, JC | 1 |
| Brunott, A | 1 |
| Weerts, EA | 1 |
| van Weeren, PR | 1 |
| Stein, C | 1 |
| Hu, HH | 1 |
| MacAllister, CG | 2 |
| Payton, ME | 2 |
| Erkert, RS | 2 |
| Clarke, CR | 1 |
| Hewes, CA | 1 |
| Schneider, RK | 1 |
| Baszler, TV | 1 |
| Oaks, JL | 1 |
| Schoonover, MJ | 1 |
| Jann, HW | 1 |
| Blaik, MA | 1 |
| Doucet, MY | 1 |
| Bertone, AL | 1 |
| Hendrickson, D | 1 |
| Hughes, F | 1 |
| Macallister, C | 1 |
| McClure, S | 1 |
| Reinemeyer, C | 1 |
| Rossier, Y | 1 |
| Sifferman, R | 1 |
| Vrins, AA | 1 |
| White, G | 1 |
| Kunkle, B | 1 |
| Alva, R | 1 |
| Romano, D | 1 |
| Hanson, PD | 1 |
| Barange, A | 1 |
| Lawrence, LM | 1 |
| Hungerford, LL | 1 |
| Keegan, KG | 1 |
| Messer, NT | 1 |
| Reed, SK | 1 |
| Wilson, DA | 1 |
| Kramer, J | 1 |
| Collins, LG | 1 |
| Tyler, DE | 1 |
| Gerring, EL | 1 |
| Lees, P | 1 |
| Taylor, JB | 1 |
| Owens, JG | 2 |
| Kamerling, SG | 2 |
| Stanton, SR | 2 |
| Keowen, ML | 2 |
| Vatistas, NJ | 1 |
| Pascoe, JR | 1 |
| Wright, IM | 1 |
| Dyson, SJ | 1 |
| Mayhew, IG | 1 |
| Prescott-Mathews, JS | 1 |
| Scott, EA | 1 |
| Mattoon, JS | 1 |
| Adams, JG | 1 |
| Riebold, TW | 1 |
| Teshera, J | 1 |
| Ritmeester, AM | 1 |
| Blevins, WE | 1 |
| Ferguson, DW | 1 |
| Adams, SB | 2 |
| Meijer, MC | 1 |
| Rijkenhuizen, AB | 1 |
| Hand, DR | 1 |
| Watkins, JP | 1 |
| Honnas, CM | 1 |
| Kemper, D | 1 |
| Squire, KR | 1 |
| Widmer, WR | 1 |
| Coatney, RW | 1 |
| Habig, C | 1 |
| Bayly, WM | 1 |
| Grant, BD | 1 |
| Gollnick, PD | 1 |
11 trials available for phenylbutazone and Gait Disorders, Animal
| Article | Year |
|---|---|
Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses.
Topics: Animals; Clonixin; Cross-Over Studies; Horse Diseases; Horses; Ketorolac; Lameness, Animal; Pain; Ph | 2020 |
Multicentre, controlled, randomised and blinded field study comparing efficacy of suxibuzone and phenylbutazone in lame horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Horse Diseases; Horse | 2009 |
Efficacy of single-dose intravenous phenylbutazone and flunixin meglumine before, during and after exercise in an experimental reversible model of foot lameness in horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Drug Administration Schedule; Female; Ho | 2010 |
Upregulation of articular synovial membrane μ-opioid-like receptors in an acute equine synovitis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Blotting, Western; Carpal Joints; Cro | 2013 |
Evaluation of the analgesic effects of phenylbutazone administered at a high or low dosage in horses with chronic lameness.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dose-Response Relationship, Dr | 2005 |
Quantitative comparison of three commonly used treatments for navicular syndrome in horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Combined Modality Therapy | 2005 |
Comparison of efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Horse Diseases; Horses; L | 2008 |
Effects of single-dose intravenous phenylbutazone on experimentally induced, reversible lameness in the horse.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Forelimb; Heart Rate; Horses; Hydrocortiso | 2008 |
Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Cross-Over Studies; Drug Therapy, Combin | 2008 |
Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Anima | 1996 |
Digital perfusion, evaluated scintigraphically, and hoof wall growth in horses with chronic laminitis treated with egg bar-heart bar shoeing and coronary grooving.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases; Hoof and C | 1998 |
15 other studies available for phenylbutazone and Gait Disorders, Animal
| Article | Year |
|---|---|
Enthesopathy and desmitis of the medial collateral ligament of the cubital joint in 4 horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Forelimb; Horse Diseases; Horses; Lameness | 2013 |
Comparative efficacy of oral meloxicam and phenylbutazone in 2 experimental pain models in the horse.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Horses; Lameness, Animal; Lipopolysacchari | 2017 |
Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses.
Topics: Animals; Clonixin; Cross-Over Studies; Drug Therapy, Combination; Female; Foot Diseases; Heart Rate; | 2011 |
Towards safer and more effective analgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Lameness, Animal; Male; Pain; Phen | 2013 |
Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Foot Diseases; Horse Diseases; Horses; I | 2005 |
Septic arthritis and granulomatous synovitis caused by infection with Mycobacterium avium complex in a horse.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Diagnosis, Differential; Gr | 2005 |
Phenylbutazone toxicosis in the horse: a clinical study.
Topics: Administration, Oral; Animals; Body Weight; Colon; Female; Horse Diseases; Horses; Hypoproteinemia; | 1984 |
Pharmacokinetics of phenylbutazone and its metabolites in the horse.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Horse Diseases; Horses; Kinetics; Lameness, Animal; | 1981 |
Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases; | 1995 |
Infection of the intertubercular bursa in horses: four cases (1978-1991).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Drug Therapy, Combination; Forelimb; Hor | 1996 |
Surgical repair of bilateral comminuted articular ulnar fractures in a seven-month-old horse.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bone Plates; Bo | 1998 |
[Navicular disease in the hind limb of a Warmblood horse].
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Female; Foot | 1999 |
Osteomyelitis of the sustentaculum tali in horses: 10 cases (1992-1998).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Debridement; Female; Follow | 2001 |
Arthroscopic removal of a palmar radial osteochondroma causing carpal canal syndrome in a horse.
Topics: Animals; Arthroscopy; Bone Neoplasms; Carpal Tunnel Syndrome; Carpus, Animal; Chemotherapy, Adjuvant | 1992 |
Standardized exercise test and daily heart rate responses of thoroughbreds undergoing conventional race training and detraining.
Topics: Animals; Heart Rate; Horses; Lactates; Lactic Acid; Lameness, Animal; Male; Phenylbutazone; Physical | 1990 |