Page last updated: 2024-11-02

phenylbutazone and Fibromyalgia

phenylbutazone has been researched along with Fibromyalgia in 10 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
" The first compared tolmetin sodium, phenylbutazone and placebo in rheumatoid arthritis."5.05Clinical experience with tolmetin sodium. ( Balme, HW; Huskisson, EC; Wojtulewski, JA, 1980)
"300 mg/day phenylbutazone, 210 mg/day indomethacin, and 600 mg/day pyrasanone were administered for 14 days to three randomised groups of patients respectively, consisting of a total of 76 subjects with various forms of non-infectious inflammation (osteoarthritis, fibrositis, rheumatoid arthritis, gout, phlebitis), in a double-blind trila designed to determine the activity of the three drugs and their tolerance."5.04[Evaluation of the effects of some non-steroid anti-inflammatory agents on the gastric mucosa]. ( Bianchi, PA; Polli, EE; Vigo, PL, 1976)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CASTAGNA, AN1
KELLY, M1
Balme, HW1
Wojtulewski, JA1
Huskisson, EC1
Bianchi, PA1
Vigo, PL1
Polli, EE1
Sperling, IL1
McGuinness, BW1
Lloyd-Jones, M1
Fowler, PD1
Klinefelter, HF1
Settel, E1
Montgomery, PR1
Wettreich, W1

Trials

3 trials available for phenylbutazone and Fibromyalgia

ArticleYear
Clinical experience with tolmetin sodium.
    Current medical research and opinion, 1980, Volume: 7, Issue:2

    Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Fibro

1980
[Evaluation of the effects of some non-steroid anti-inflammatory agents on the gastric mucosa].
    Minerva medica, 1976, Jul-07, Volume: 67, Issue:33

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Diarrhea; Drug Tolerance; Female; Fibromyalgia; Gas

1976
A double-blind comparative trial of 'parazolidin' and paracetamol.
    The British journal of clinical practice, 1969, Volume: 23, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Back Pain; Clinical Trials as Topic; Elbow Joint; Female; Fi

1969

Other Studies

7 other studies available for phenylbutazone and Fibromyalgia

ArticleYear
[CONTRIBUTION TO THE STUDY OF INFLAMMATORY DISEASES OF THE LOCOMOTOR APPARATUS].
    La Semana medica, 1964, Apr-23, Volume: 124

    Topics: Antidepressive Agents; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Fibromyalgia; Humans; Opipram

1964
INDOMETHACIN, REMARKABLE ANTIRHEUMATIC DRUG.
    The Medical journal of Australia, 1964, Oct-03, Volume: 2

    Topics: Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Fibromyalgia; Geriatrics; Gout

1964
Adverse reactions with long-term use of phenylbutazone and oxyphenbutazone.
    Lancet (London, England), 1969, Sep-06, Volume: 2, Issue:7619

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Digestive System; Edema; Female; Fibromyalgia

1969
Primary fibrositis and its treatment with the pyrazolone derivatives, butazolidin and tandearil.
    The Johns Hopkins medical journal, 1972, Volume: 130, Issue:5

    Topics: Adult; Age Factors; Diagnosis, Differential; Drug Eruptions; Edema; Female; Fibromyalgia; Humans; Ma

1972
Efficacy of a phenylbutazone-prednisone combination in the treatment of acute lumbosacral fibrositis: a survey of 96 cases.
    Current therapeutic research, clinical and experimental, 1967, Volume: 9, Issue:4

    Topics: Fibromyalgia; Humans; Lumbosacral Region; Phenylbutazone; Prednisone

1967
Toxic epidermal necrolysis due to phenylbutazone.
    The British journal of dermatology, 1970, Volume: 83, Issue:1

    Topics: Adult; Female; Fibromyalgia; Humans; Phenylbutazone; Stevens-Johnson Syndrome

1970
[The association of paracetamol and phenylbutazone in rheumatology. Preliminary report].
    Hospital (Rio de Janeiro, Brazil), 1966, Volume: 70, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Female; Fibromyalgia; Humans;

1966