Page last updated: 2024-11-02

phenylbutazone and Equine Diseases

phenylbutazone has been researched along with Equine Diseases in 135 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
" Anecdotally, many practitioners prescribe omeprazole concurrently with phenylbutazone to reduce development of equine gastric ulcer syndrome (EGUS), but the efficacy and safety of this practice remains unknown."9.41Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS). ( Andrews, FM; Banse, HE; Chapman, A; Garza, F; Keowen, M; Paul, L; Ricord, M; Yñiguez, FJM, 2021)
"To assess the clinical, biochemical, and histologic effects of topically administered diclofenac liposomal cream (DLC) in the treatment of horses with experimentally induced osteoarthritis."9.14Evaluation of topically administered diclofenac liposomal cream for treatment of horses with experimentally induced osteoarthritis. ( Frisbie, DD; Kawcak, CE; McIlwraith, CW; Pearce, GL; Werpy, NM, 2009)
"To compare efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis."9.13Comparison of efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis. ( Alva, R; Bertone, AL; Doucet, MY; Hanson, PD; Hendrickson, D; Hughes, F; Kunkle, B; Macallister, C; McClure, S; Reinemeyer, C; Romano, D; Rossier, Y; Sifferman, R; Vrins, AA; White, G, 2008)
"The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours."9.08Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996)
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone."7.77Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011)
"In horses with navicular syndrome treated once daily for 4 days, typical clinical doses of flunixin and phenylbutazone resulted in similar significant improvement in lameness at 6, 12, and 24 hours after the final dose, compared with findings in horses treated with saline solution."7.73Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome. ( Clarke, CR; Erkert, RS; MacAllister, CG; Payton, ME, 2005)
"Phenylbutazone (PBZ) toxicosis was induced in 9 ponies to further define the clinical and pathologic changes occurring with this syndrome."7.67Experimentally induced phenylbutazone toxicosis in ponies: description of the syndrome and its prevention with synthetic prostaglandin E2. ( Collins, LG; Tyler, DE, 1985)
"Phenylbutazone has been shown to alter GI barrier function both in vitro and ex vivo, but its effects on barrier function have not been assessed in vivo."7.01Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses. ( Bradbery, A; Chamoun-Emanuelli, AM; Cohen, ND; Coleman, MC; DeSolis, CN; Much, M; Sowinski, R; Tetrault, T; Whitfield-Cargile, CM, 2021)
"Ketorolac tromethamine was not superior to FM or PB in reducing lameness using a HBS model."6.94Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses. ( Brunner, TJ; Cooper, BR; Davern, AJ; Grady, SE; Lescun, TB; Moore, GE; Taylor, SD, 2020)
"Although PBZ is clinically effective in treating acute synovitis, it does not limit inflammation-induced cartilage catabolism and may transiently reduce collagen anabolism as evidenced by SF markers."6.79In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis. ( Brunott, A; de Grauw, JC; van de Lest, CH; van Loon, JP; van Weeren, PR, 2014)
" The objectives of the current study were to describe blood and urine concentrations and the pharmacokinetics of PBZ and its metabolites following intravenous (IV) and oral administration and to describe the duration of pharmacodynamic effect."5.51Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses. ( Arthur, RM; Hamamoto-Hardman, B; Kass, PH; Knych, HK; McKemie, DS; Seminoff, K, 2019)
" Anecdotally, many practitioners prescribe omeprazole concurrently with phenylbutazone to reduce development of equine gastric ulcer syndrome (EGUS), but the efficacy and safety of this practice remains unknown."5.41Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS). ( Andrews, FM; Banse, HE; Chapman, A; Garza, F; Keowen, M; Paul, L; Ricord, M; Yñiguez, FJM, 2021)
" One group received a high dose of PBZ for two weeks; the second group was given an equimolecular dosage of SBZ; and a third group received placebo."5.32Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses. ( Homedes, J; Mayós, I; Monreal, L; Sabaté, D; Segura, D, 2004)
"Hoof pain was quantified objectively by means of an electronic hoof tester and lameness was subjectively graded on a modified Obel scale."5.29Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. ( Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR, 1995)
"Phenylbutazone was cleared more slowly from exudate than from plasma."5.27Effects of a phenylbutazone paste in ponies: model of acute nonimmune inflammation. ( Higgins, AJ; Lees, P, 1986)
"To assess the clinical, biochemical, and histologic effects of topically administered diclofenac liposomal cream (DLC) in the treatment of horses with experimentally induced osteoarthritis."5.14Evaluation of topically administered diclofenac liposomal cream for treatment of horses with experimentally induced osteoarthritis. ( Frisbie, DD; Kawcak, CE; McIlwraith, CW; Pearce, GL; Werpy, NM, 2009)
"To compare efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis."5.13Comparison of efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis. ( Alva, R; Bertone, AL; Doucet, MY; Hanson, PD; Hendrickson, D; Hughes, F; Kunkle, B; Macallister, C; McClure, S; Reinemeyer, C; Romano, D; Rossier, Y; Sifferman, R; Vrins, AA; White, G, 2008)
"The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours."5.08Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996)
"Although both classes of NSAID induced gastric ulceration, the COX-2 selective NSAID firocoxib induced less severe glandular ulceration."3.88Effect of selective versus nonselective cyclooxygenase inhibitors on gastric ulceration scores and intestinal inflammation in horses. ( Chamoun-Emanuelli, AM; Cohen, ND; Dockery, HJ; Richardson, LM; Whitfield-Cargile, CM, 2018)
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone."3.77Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011)
"Using an adjustable heart bar shoe model of foot pain, the objective of this study was to test the hypothesis that the combined use of phenylbutazone (PBZ) and flunixin meglumine (FM) would prove more efficacious in alleviating lameness than either drug alone."3.77Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses. ( Foreman, JH; Ruemmler, R, 2011)
"In horses with navicular syndrome treated once daily for 4 days, typical clinical doses of flunixin and phenylbutazone resulted in similar significant improvement in lameness at 6, 12, and 24 hours after the final dose, compared with findings in horses treated with saline solution."3.73Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome. ( Clarke, CR; Erkert, RS; MacAllister, CG; Payton, ME, 2005)
"In these Thoroughbreds, phenylbutazone treatment did not modify heart rate or right atrial and pulmonary vascular pressures at rest or during exercise capable of eliciting exercise-induced pulmonary hemorrhage."3.69Pulmonary vascular pressures of strenuously exercising thoroughbreds after administration of phenylbutazone. ( Goetz, TE; Griffin, R; Manohar, M; Sullivan, E, 1996)
"Phenylbutazone (PBZ) toxicosis was induced in 9 ponies to further define the clinical and pathologic changes occurring with this syndrome."3.67Experimentally induced phenylbutazone toxicosis in ponies: description of the syndrome and its prevention with synthetic prostaglandin E2. ( Collins, LG; Tyler, DE, 1985)
"During 1975 and 1976, 70 Standardbred horses with cunean bursitis-tarsitis were treated by cunean tenectomy or by more conservative approaches (rested, given corticosteroid injections in the cunean bursa and distal hock articulations, given an oral course of phenylbutazone, a combination of these) or were sold."3.66Treatment and prognosis for cunean tendon bursitis-tarsitis of Standardbred horses. ( Gabel, AA, 1979)
"Phenylbutazone has been shown to alter GI barrier function both in vitro and ex vivo, but its effects on barrier function have not been assessed in vivo."3.01Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses. ( Bradbery, A; Chamoun-Emanuelli, AM; Cohen, ND; Coleman, MC; DeSolis, CN; Much, M; Sowinski, R; Tetrault, T; Whitfield-Cargile, CM, 2021)
"Ketorolac tromethamine was not superior to FM or PB in reducing lameness using a HBS model."2.94Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses. ( Brunner, TJ; Cooper, BR; Davern, AJ; Grady, SE; Lescun, TB; Moore, GE; Taylor, SD, 2020)
"Although PBZ is clinically effective in treating acute synovitis, it does not limit inflammation-induced cartilage catabolism and may transiently reduce collagen anabolism as evidenced by SF markers."2.79In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis. ( Brunott, A; de Grauw, JC; van de Lest, CH; van Loon, JP; van Weeren, PR, 2014)
"Phenylbutazone paste was administered at approximately 2."2.73Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses. ( Keegan, KG; Kramer, J; Messer, NT; Reed, SK; Wilson, DA, 2008)
"To compare analgesic effects of phenylbutazone administered at a dosage of 4."2.71Evaluation of the analgesic effects of phenylbutazone administered at a high or low dosage in horses with chronic lameness. ( Erkert, RS; Hu, HH; MacAllister, CG; Payton, ME, 2005)
"Phenylbutazone was administered as before, and PVGRF was measured."2.71Quantitative comparison of three commonly used treatments for navicular syndrome in horses. ( Blaik, MA; Jann, HW; Schoonover, MJ, 2005)
" The plasma kinetics of phenylbutazone may be dose dependent, with the plasma half-life increasing as the drug dosage level increases."2.37Phenylbutazone in the horse: a review. ( Blake, JW; Chay, S; Kamerling, S; Lees, P; Tobin, T; Weckman, TJ; Woods, WE, 1986)
"Arachidonic acid is a polyunsaturated fatty acid covalently bound in esterified form in the cell membranes of most body cells."2.37The acute inflammatory process, arachidonic acid metabolism and the mode of action of anti-inflammatory drugs. ( Higgins, AJ; Lees, P, 1984)
" The objectives of the current study were to describe blood and urine concentrations and the pharmacokinetics of PBZ and its metabolites following intravenous (IV) and oral administration and to describe the duration of pharmacodynamic effect."1.51Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses. ( Arthur, RM; Hamamoto-Hardman, B; Kass, PH; Knych, HK; McKemie, DS; Seminoff, K, 2019)
" The goal of this study was to determine the safety of a 10-day dosage regimen of phenylbutazone and firocoxib, both at their standard dosages, in horses."1.40Evaluation of the safety of a combination of oral administration of phenylbutazone and firocoxib in horses. ( Kivett, L; Taintor, J; Wright, J, 2014)
" Veterinarians should monitor serum albumin concentrations and neutrophil counts and be cautious when making dosing recommendations for phenylbutazone treatment of horses."1.35Pathophysiologic effects of phenylbutazone on the right dorsal colon in horses. ( Hubert, JD; McConnico, RS; Moore, RM; Morgan, TW; Williams, CC, 2008)
" One group received a high dose of PBZ for two weeks; the second group was given an equimolecular dosage of SBZ; and a third group received placebo."1.32Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses. ( Homedes, J; Mayós, I; Monreal, L; Sabaté, D; Segura, D, 2004)
"Pulmonary granular cell tumor is a locally invasive but rare type of tumor with low metastatic potential."1.31Treatment of granular cell tumor via complete right lung resection in a horse. ( Adams, SB; Chilcoat, CD; Dutweiler, VA; Facemire, PR; Irizarry, AR; Morisset, SS; Sojka, JE; Weirich, WE, 2000)
"The therapy was repeated following recurrence of the lameness."1.30[Navicular disease in the hind limb of a Warmblood horse]. ( Meijer, MC; Rijkenhuizen, AB, 1999)
" Pharmacokinetic variables calculated for each drug when given alone and in combination were similar to those reported."1.29Effects of concurrent administration of phenylbutazone and flunixin meglumine on pharmacokinetic variables and in vitro generation of thromboxane B2 in mares. ( Ashcraft, SM; Harris, ON; Sams, RA; Semrad, SD, 1993)
"Phenylbutazone-treated horses had a significant (P < 0."1.29Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses. ( Borne, AT; MacAllister, CG; Morgan, SJ; Pollet, RA, 1993)
"Hoof pain was quantified objectively by means of an electronic hoof tester and lameness was subjectively graded on a modified Obel scale."1.29Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. ( Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR, 1995)
"Phenylbutazone was more effective than flunixin and this was significant (P < 0."1.28Antagonism of endotoxin-induced disruption of equine bowel motility by flunixin and phenylbutazone. ( Gerring, EL; King, JN, 1989)
"oral phenylbutazone treatment over the next 3 years allowed the stallion to continue its show career."1.28Arthroscopic removal of a palmar radial osteochondroma causing carpal canal syndrome in a horse. ( Adams, SB; Coatney, RW; Habig, C; Squire, KR; Widmer, WR, 1992)
"Phenylbutazone is a potent nonsteroidal, anti-inflammatory drug often used by veterinarians to treat racetrack animals."1.28Poisoning with equine phenylbutazone in a racetrack worker. ( Newton, TA; Rose, SR, 1991)
" Phenylbutazone was administered at a dosage of 10 mg/kg of bodyweight (BW) per day, intravenously (IV), in equally divided doses to three of the groups."1.28The protective effects of sucralfate and ranitidine in foals experimentally intoxicated with phenylbutazone. ( Geor, RJ; Papich, MG; Petrie, L; Rousseaux, C, 1989)
" A decrease in total blood neutrophil count occurred in all horses, and was associated with toxic left shift in horses given the 2 larger dosage schedules."1.27Effects of large doses of phenylbutazone administration to horses. ( French, TW; MacKay, RJ; Mayhew, IG; Nguyen, HT, 1983)
"Five pairs of matched horses were used to study the biochemical and haematological effects of a revised dosage schedule of phenylbutazone."1.27Biochemical and haematological effects of a revised dosage schedule of phenylbutazone in horses. ( Gerring, EL; Lees, P; Maitho, TE; Millar, JD; Taylor, JB; Walland, A, 1983)
"This case was unusual because septicemia with salmonellosis is an uncommon finding in adult equids."1.27Septicemic salmonellosis and suspected phenylbutazone toxicosis in an aged pony. ( Hondalus, MK; Lofstedt, J, 1988)
"Phenylbutazone was cleared more slowly from exudate than from plasma."1.27Effects of a phenylbutazone paste in ponies: model of acute nonimmune inflammation. ( Higgins, AJ; Lees, P, 1986)
" The results suggested that at a similar dose rate of 5 mg/kg greater bioavailability results from the paste than from a powder preparation."1.27Studies on a new paste preparation of phenylbutazone. ( Douglas, TA; Snow, DH, 1983)
"Phenylbutazone (PBZ) is a nonsteroidal antiinflammatory drug (NSAID) that is not commonly prescribed due to the high incidence of serious adverse reactions."1.27Horse pill ("bute") hemorrhage. ( Cohen, ML; Davis, M; Gogel, HK; Ming, RH; Pitcher, JL, 1988)
" Considerable individual variation was observed both in timing and magnitude of the plasma drug responses between horses, but 24 h after dosing a clear dose response relation was recorded."1.26Pharmacokinetics of phenylbutazone and its metabolites in the horse. ( Gerring, EL; Lees, P; Taylor, JB, 1981)
" At dosage levels of 10 to 12 mg/kg of body weight/day for 8 to 10 days, ponies frequently developed clinical signs of toxicosis characterized by hypoproteinemia."1.26Phenylbutazone toxicosis in equidae: a biochemical and pathophysiological study. ( Douglas, TA; Holmes, PH; Parkins, JJ; Snow, DH; Thompson, H, 1981)

Research

Studies (135)

TimeframeStudies, this research(%)All Research%
pre-199051 (37.78)18.7374
1990's28 (20.74)18.2507
2000's33 (24.44)29.6817
2010's18 (13.33)24.3611
2020's5 (3.70)2.80

Authors

AuthorsStudies
Meinke, PT1
Ahmadnejad, M1
Jalilzadeh-Amin, G1
Sykes, BW1
Ricord, M1
Andrews, FM2
Yñiguez, FJM1
Keowen, M1
Garza, F1
Paul, L1
Chapman, A1
Banse, HE2
Grady, SE1
Lescun, TB1
Moore, GE1
Cooper, BR1
Davern, AJ1
Brunner, TJ1
Taylor, SD1
Whitfield-Cargile, CM2
Coleman, MC1
Cohen, ND2
Chamoun-Emanuelli, AM2
DeSolis, CN1
Tetrault, T1
Sowinski, R1
Bradbery, A1
Much, M1
van Galen, G1
Saegerman, C1
Hyldahl Laursen, S1
Jacobsen, S1
Andersson Munk, M1
Sjöström, H1
Holm Lindmark, S1
Verwilghen, D1
Pedersen, SK1
Cribb, AE1
Read, EK1
French, D1
Richardson, LM1
Dockery, HJ1
Knych, HK1
Arthur, RM1
McKemie, DS1
Seminoff, K1
Hamamoto-Hardman, B1
Kass, PH1
Tesena, P1
Yingchutrakul, Y1
Roytrakul, S1
Wongtawan, T1
Angkanaporn, K1
Dabareiner, RM1
Chaffin, MK1
Quirham, H1
Carter, GK2
Sandmeyer, LS1
Bauer, BS1
Grahn, BH1
Kivett, L1
Taintor, J1
Wright, J1
de Grauw, JC2
van Loon, JP2
van de Lest, CH1
Brunott, A2
van Weeren, PR2
Martínez Aranzales, JR1
Cândido de Andrade, BS1
Silveira Alves, GE1
Fodey, TL1
Smyth, WG1
Barnes, P1
Traynor, IM1
Kennedy, DG1
Crooks, SR1
Bonilla, AG1
Santschi, EM1
Longhofer, SL2
Reinemeyer, CR2
Radecki, SV1
Cohausz, O1
Müntener, CR1
Trachsel, D1
Wimmershoff, J1
Eser, MW1
McConnico, RS1
Morgan, TW1
Williams, CC1
Hubert, JD1
Moore, RM1
Frisbie, DD1
McIlwraith, CW2
Kawcak, CE1
Werpy, NM1
Pearce, GL1
Sabaté, D2
Homedes, J2
Salichs, M1
Sust, M1
Monreal, L2
Foreman, JH2
Grubb, TL1
Inoue, OJ1
Banner, SE1
Ball, KT1
Soma, LR2
Uboh, CE1
Maylin, GM1
Aleman, M1
Nieto, JE1
Higgins, JK1
Ruemmler, R1
Clark-Price, SC1
Gutierrez-Nibeyro, SD1
Santos, MP1
Weerts, EA1
Stein, C1
Jones, SL1
Davis, J1
Rowlingson, K1
Segura, D1
Mayós, I1
Morton, AJ1
Campbell, NB1
Gayle, JM1
Redding, WR1
Blikslager, AT1
Hu, HH1
MacAllister, CG4
Payton, ME2
Erkert, RS2
Clarke, CR1
Hewes, CA1
Schneider, RK1
Baszler, TV1
Oaks, JL1
Xie, H1
Colahan, P1
Ott, EA1
Schoonover, MJ1
Jann, HW1
Blaik, MA1
Groves, L1
Reed, SK2
Messer, NT2
Tessman, RK1
Keegan, KG2
Mogg, TD2
Rutherford, DJ1
Stewart, AJ1
Hart, J1
Wearn, J1
Katz, L1
Sullivan, KA1
Hill, AE1
Haussler, KK1
Doucet, MY1
Bertone, AL3
Hendrickson, D1
Hughes, F1
Macallister, C1
McClure, S1
Reinemeyer, C1
Rossier, Y1
Sifferman, R1
Vrins, AA1
White, G1
Kunkle, B1
Alva, R1
Romano, D1
Hanson, PD1
Boissevain, I1
Wilson, DA1
Kramer, J1
de Grauw, J1
Lipman, LJ1
Vogel, C1
Higgins, AJ3
Lees, P10
Faulkner, LW1
Erb, HN2
King, JM2
Taylor, JB5
Gunson, DE2
Verrall, JH2
Snow, DH6
Chandler, N1
Jones, RD1
Parker, J1
Traub, JL1
Gallina, AM1
Grant, BD1
Reed, SM1
Gavin, PR1
Paulsen, LM1
Power, HT1
Watrous, BJ1
de Lahunta, A1
Read, WK1
Gerring, EL4
Collins, LG2
Tyler, DE2
Meschter, CL2
Maylin, GA1
Krook, L2
Burrows, GE1
MacKay, RJ1
French, TW1
Nguyen, HT1
Mayhew, IG2
Walland, A1
Maitho, TE1
Millar, JD1
Douglas, TA4
Miller, RM1
Dresher, LK1
Hodgson, DR1
Jacobs, KA1
Thompson, H3
Parkins, JJ2
Holmes, PH2
Snow, D1
White, NA2
Johnson, CB1
Taylor, PM1
Young, SS1
Brearley, JC1
Semrad, SD1
Sams, RA1
Harris, ON1
Ashcraft, SM1
Morgan, SJ1
Borne, AT1
Pollet, RA1
Perrin, J1
Cosmetatos, I1
Gallusser, A1
Lobsiger, L1
Straub, R1
Nicolet, J1
Owens, JG2
Kamerling, SG2
Stanton, SR2
Keowen, ML2
Vatistas, NJ1
Pascoe, JR1
Wright, IM1
Dyson, SJ1
Slater, MR1
Hood, DM1
Prescott-Mathews, JS1
Manohar, M1
Goetz, TE1
Griffin, R1
Sullivan, E1
May, SA1
Hooke, RE1
Brusie, RW1
Sullins, KE1
Coffin, PC1
Parker, GA1
Anver, MR1
Rosenberger, JL1
King, JN1
Colbourne, CM1
Raidal, SL1
Yovich, JV2
Howell, JM1
Richardson, JL1
Warmerdam, EP1
Klein, WR1
van Herpen, BP1
Rijkenhuizen, AB2
van Swieten, HA1
Sertich, PL1
Pozor, MA1
Meyers, SA1
Brown, JS1
Ramirez, S1
Seahorn, TL1
Williams, J1
Ritmeester, AM1
Blevins, WE1
Ferguson, DW1
Adams, SB3
Van Harreveld, PD1
Gaughan, EM2
Meijer, MC1
Hough, ME1
Steel, CM1
Bolton, JR1
Rohde, C1
Anderson, DE1
Weisbrode, SE1
Trumble, TN1
Ingle-Fehr, J1
Hendrickson, DA1
Reilly, FK1
Adair, HS1
Goble, DO1
Schmidhammer, JL1
Shires, GM1
Facemire, PR1
Chilcoat, CD1
Sojka, JE2
Irizarry, AR1
Weirich, WE1
Morisset, SS1
Dutweiler, VA1
Hawkins, JF1
Frank, N1
Levy, M1
Hand, DR1
Watkins, JP1
Honnas, CM1
Kemper, D1
Jeffcott, LB1
Colles, CM1
Chand, N1
Eyre, P1
Gabel, AA1
Michell, AR1
Bogan, JA1
Ackerman, N1
Johnson, JH1
Dorn, CR1
Squire, KR1
Widmer, WR1
Coatney, RW1
Habig, C1
Auer, DE2
Ng, JC2
Reilly, JS1
Seawright, AA2
Newton, TA1
Rose, SR1
Tulleners, EP1
Simmons, TR1
Ducharme, NG1
Dill, SG1
Anderson, WI1
Ellison, RS1
Jacobs, RM1
Gilbert, M1
Maylin, G1
Corradino, R1
Geor, RJ1
Petrie, L1
Papich, MG1
Rousseaux, C1
Cohen, ML1
Ming, RH1
Gogel, HK1
Davis, M1
Pitcher, JL1
Hondalus, MK1
Lofstedt, J1
Tobin, T1
Chay, S1
Kamerling, S1
Woods, WE1
Weckman, TJ1
Blake, JW1
Neaderland, MH1
Riis, RC1
Rebhun, WC1
Jones, RL1
Norrdin, RW1
Radin, MJ1
Lebel, JL1
van Miert, AS1
Hunt, JM1
Edwards, GB1
Hopes, R1
Coffman, JR1
Garner, HE1
Dunn, PS1
Moss, MS1
Steck, W1

Reviews

7 reviews available for phenylbutazone and Equine Diseases

ArticleYear
Perspectives in animal health: old targets and new opportunities.
    Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5

    Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anti-Ulcer Age

2001
The use of phenylbutazone in the horse.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Legislation, Drug; Phenylb

2012
The acute inflammatory process, arachidonic acid metabolism and the mode of action of anti-inflammatory drugs.
    Equine veterinary journal, 1984, Volume: 16, Issue:3

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blo

1984
Phenylbutazone and the horse--a review.
    Equine veterinary journal, 1977, Volume: 9, Issue:3

    Topics: Agranulocytosis; Anemia; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Horse Diseases; Horses; Hu

1977
Nonsteroidal anti-inflammatory drugs: a review. New applications in hypersensitivity reactions of cattle and horses.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1977, Volume: 41, Issue:3

    Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Arthritis; Ascariasis; Aspirin; Cattle; Cattle Disea

1977
Phenylbutazone in the horse: a review.
    Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:1

    Topics: Animals; Biological Availability; Blood Proteins; Horse Diseases; Horses; Kinetics; Pain; Phenylbuta

1986
Acute laminitis.
    Journal of the American Veterinary Medical Association, 1972, Dec-01, Volume: 161, Issue:11

    Topics: Acute Disease; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Cathartics; Cystine; Hoof an

1972

Trials

21 trials available for phenylbutazone and Equine Diseases

ArticleYear
Prophylactic effects of Glycyrrhiza glabra root extract on phenylbutazone-induced Equine Glandular Gastric Disease (EGGD).
    Journal of equine veterinary science, 2022, Volume: 118

    Topics: Animals; Antioxidants; Glycyrrhiza; Horse Diseases; Horses; Phenylbutazone; Stomach Diseases

2022
Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS).
    Equine veterinary journal, 2021, Volume: 53, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Omeprazole; Phenylbutazone

2021
Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses.
    Journal of equine veterinary science, 2020, Volume: 94

    Topics: Animals; Clonixin; Cross-Over Studies; Horse Diseases; Horses; Ketorolac; Lameness, Animal; Pain; Ph

2020
Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Microbiota; Permeability;

2021
Phenylbutazone induces equine glandular gastric disease without decreasing prostaglandin E
    Journal of veterinary pharmacology and therapeutics, 2018, Volume: 41, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Enzyme-Linked Immunosorbent Assay; G

2018
In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis.
    Veterinary journal (London, England : 1997), 2014, Volume: 201, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Collagen Type II

2014
Evaluation of the palatability of three nonsteroidal antiinflammatory top-dress formulations in horses.
    Veterinary therapeutics : research in applied veterinary medicine, 2008,Summer, Volume: 9, Issue:2

    Topics: Administration, Oral; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Stud

2008
Evaluation of topically administered diclofenac liposomal cream for treatment of horses with experimentally induced osteoarthritis.
    American journal of veterinary research, 2009, Volume: 70, Issue:2

    Topics: Administration, Topical; Animals; Arthrography; Cartilage, Articular; Diclofenac; Histocytochemistry

2009
Multicentre, controlled, randomised and blinded field study comparing efficacy of suxibuzone and phenylbutazone in lame horses.
    Equine veterinary journal, 2009, Volume: 41, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Horse Diseases; Horse

2009
Effects of top-dress formulations of suxibuzone and phenylbutazone on development of gastric ulcers in horses.
    Veterinary therapeutics : research in applied veterinary medicine, 2009,Fall, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; F

2009
Efficacy of single-dose intravenous phenylbutazone and flunixin meglumine before, during and after exercise in an experimental reversible model of foot lameness in horses.
    Equine veterinary journal. Supplement, 2010, Issue:38

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Drug Administration Schedule; Female; Ho

2010
Upregulation of articular synovial membrane μ-opioid-like receptors in an acute equine synovitis model.
    Veterinary journal (London, England : 1997), 2013, Volume: 196, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Blotting, Western; Carpal Joints; Cro

2013
Evaluation of the analgesic effects of phenylbutazone administered at a high or low dosage in horses with chronic lameness.
    Journal of the American Veterinary Medical Association, 2005, Feb-01, Volume: 226, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dose-Response Relationship, Dr

2005
Quantitative comparison of three commonly used treatments for navicular syndrome in horses.
    American journal of veterinary research, 2005, Volume: 66, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Combined Modality Therapy

2005
Effects of phenylbutazone alone or in combination with flunixin meglumine on blood protein concentrations in horses.
    American journal of veterinary research, 2006, Volume: 67, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Clonixin; Drug Therapy, Combinatio

2006
The effects of chiropractic, massage and phenylbutazone on spinal mechanical nociceptive thresholds in horses without clinical signs.
    Equine veterinary journal, 2008, Volume: 40, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Biomechanical Phenomena; Combined Modal

2008
Comparison of efficacy and safety of paste formulations of firocoxib and phenylbutazone in horses with naturally occurring osteoarthritis.
    Journal of the American Veterinary Medical Association, 2008, Jan-01, Volume: 232, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Horse Diseases; Horses; L

2008
Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses.
    American journal of veterinary research, 2008, Volume: 69, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Cross-Over Studies; Drug Therapy, Combin

2008
Postoperative analgesia using phenylbutazone, flunixin or carprofen in horses.
    The Veterinary record, 1993, Oct-02, Volume: 133, Issue:14

    Topics: Analgesia; Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butorphanol; Carbazoles; Cl

1993
Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses.
    American journal of veterinary research, 1996, Volume: 57, Issue:6

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Anima

1996
Digital perfusion, evaluated scintigraphically, and hoof wall growth in horses with chronic laminitis treated with egg bar-heart bar shoeing and coronary grooving.
    Equine veterinary journal. Supplement, 1998, Issue:26

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases; Hoof and C

1998

Other Studies

107 other studies available for phenylbutazone and Equine Diseases

ArticleYear
Colonic Health in Hospitalized Horses Treated with Non-Steroidal Anti-Inflammatory Drugs - A Preliminary Study.
    Journal of equine veterinary science, 2021, Volume: 101

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Horse Diseases; Horses; Pharmaceutical Prep

2021
Effect of selective versus nonselective cyclooxygenase inhibitors on gastric ulceration scores and intestinal inflammation in horses.
    Veterinary surgery : VS, 2018, Volume: 47, Issue:6

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Fece

2018
Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses.
    Drug testing and analysis, 2019, Volume: 11, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal;

2019
Serum protein expression in Equine Glandular Gastric Disease (EGGD) induced by phenylbutazone.
    The Journal of veterinary medical science, 2019, Mar-20, Volume: 81, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Horse Diseases; Horses; Male; Phen

2019
Enthesopathy and desmitis of the medial collateral ligament of the cubital joint in 4 horses.
    Journal of the American Veterinary Medical Association, 2013, Apr-15, Volume: 242, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Forelimb; Horse Diseases; Horses; Lameness

2013
Diagnostic ophthalmology. Anterior uveitis of the right eye.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2013, Volume: 54, Issue:9

    Topics: Animals; Atropine; Female; Horse Diseases; Horses; Phenylbutazone; Prednisolone; Uveitis, Anterior

2013
Evaluation of the safety of a combination of oral administration of phenylbutazone and firocoxib in horses.
    Journal of veterinary pharmacology and therapeutics, 2014, Volume: 37, Issue:4

    Topics: 4-Butyrolactone; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Prote

2014
Orally administered phenylbutazone causes oxidative stress in the equine gastric mucosa.
    Journal of veterinary pharmacology and therapeutics, 2015, Volume: 38, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Dinoprostone; Fema

2015
Investigation into sources of contamination of cattle with phenylbutazone.
    The Veterinary record, 2015, Jan-17, Volume: 176, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Drug Residues; Feeding Methods; Food Conta

2015
Comminuted fracture of the accessory carpal bone removed via an arthroscopic-assisted arthrotomy.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Carpal Bones;

2015
[Drug interactions of phenylbutazone and phenprocoumon in a warmblood gelding].
    Schweizer Archiv fur Tierheilkunde, 2008, Volume: 150, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Blood Coagulation Disorders; Drug

2008
Pathophysiologic effects of phenylbutazone on the right dorsal colon in horses.
    American journal of veterinary research, 2008, Volume: 69, Issue:11

    Topics: Animals; Colitis; Colon; Cross-Over Studies; Fatty Acids; Horse Diseases; Horses; Malondialdehyde; P

2008
Ulcerative cystitis associated with phenylbutazone administration in two horses.
    Journal of the American Veterinary Medical Association, 2011, Aug-15, Volume: 239, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cystitis; Hematuria; Horse Dise

2011
Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses.
    Equine veterinary journal. Supplement, 2011, Issue:40

    Topics: Animals; Clonixin; Cross-Over Studies; Drug Therapy, Combination; Female; Foot Diseases; Heart Rate;

2011
Anesthesia case of the month. EPAM.
    Journal of the American Veterinary Medical Association, 2012, Jan-01, Volume: 240, Issue:1

    Topics: Analgesics; Anesthesia, General; Anesthetics, General; Animals; Anti-Inflammatory Agents; Clonixin;

2012
Towards safer and more effective analgesia.
    Veterinary journal (London, England : 1997), 2013, Volume: 196, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Lameness, Animal; Male; Pain; Phen

2013
Ultrasonographic findings in horses with right dorsal colitis: five cases (2000-2001).
    Journal of the American Veterinary Medical Association, 2003, May-01, Volume: 222, Issue:9

    Topics: Abdominal Pain; Animals; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Colitis; Col

2003
Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses.
    Research in veterinary science, 2004, Volume: 76, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastric Mucosa; Horse Diseases; Horses; Ma

2004
Preferential and non-selective cyclooxygenase inhibitors reduce inflammation during lipopolysaccharide-induced synovitis.
    Research in veterinary science, 2005, Volume: 78, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme-Linked Immunosorb

2005
Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome.
    American journal of veterinary research, 2005, Volume: 66, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Foot Diseases; Horse Diseases; Horses; I

2005
Septic arthritis and granulomatous synovitis caused by infection with Mycobacterium avium complex in a horse.
    Journal of the American Veterinary Medical Association, 2005, Jun-15, Volume: 226, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Diagnosis, Differential; Gr

2005
Evaluation of electroacupuncture treatment of horses with signs of chronic thoracolumbar pain.
    Journal of the American Veterinary Medical Association, 2005, Jul-15, Volume: 227, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Chronic Disease; Electroacupuncture; Fe

2005
Chip fractures from the distal lateral trochlear ridge of the talus of a quarter horse gelding: a veterinary medicine clinical report.
    Cellular and molecular biology (Noisy-le-Grand, France), 2005, Sep-05, Volume: 51, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Combined Modality Therapy; Fractures,

2005
Intra-abdominal abscess and peritonitis in an Appaloosa gelding.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Abdominal Abscess; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Gentamic

2006
Actinobacillus pleuritis and peritonitis in a quarter horse mare.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Actinobacillus; Actinobacillus Infections; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents,

2006
Postpartum hemoperitoneum and septic peritonitis in a Thoroughbred mare.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Abdominal Cavity; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonixin;

2006
Left otitis media/interna and right maxillary sinusitis in a Percheron mare.
    The Veterinary clinics of North America. Equine practice, 2006, Volume: 22, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Dimethyl Sulfoxide; Drug Combinations; Fac

2006
[Horse product].
    Tijdschrift voor diergeneeskunde, 2007, Dec-15, Volume: 132, Issue:24

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catheterization; Colic; Horse Diseases; Horses; Le

2007
[Phenylbutazone, the black 'horse' of the NSAID family?].
    Tijdschrift voor diergeneeskunde, 2008, Mar-15, Volume: 133, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Cost-Benefit Analysis; European Union

2008
From firing to phenylbutazone in equine practice.
    The Veterinary record, 1982, Dec-04, Volume: 111, Issue:23

    Topics: Animals; History, 19th Century; History, 20th Century; Horse Diseases; Horses; Influenza A virus; Or

1982
Renal papillary necrosis in equines.
    Bulletin of environmental contamination and toxicology, 1984, Volume: 33, Issue:4

    Topics: Animals; Clonixin; Horse Diseases; Horses; Kidney Papillary Necrosis; Nicotinic Acids; Phenylbutazon

1984
Influence of phenylbutazone on eicosanoid levels in equine acute inflammatory exudate.
    The Cornell veterinarian, 1984, Volume: 74, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cell Migration Inhibition; Dinoprostone; Exudates and Transud

1984
Renal papillary necrosis in horses.
    Journal of the American Veterinary Medical Association, 1983, Feb-01, Volume: 182, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clonixin; Dehyd

1983
Paste preparation of phenylbutazone.
    The Veterinary record, 1983, Jul-09, Volume: 113, Issue:2

    Topics: Animals; Horse Diseases; Horses; Ointments; Phenylbutazone

1983
Paste preparation of phenylbutazone.
    The Veterinary record, 1983, Jul-23, Volume: 113, Issue:4

    Topics: Animals; Horse Diseases; Horses; Ointments; Phenylbutazone

1983
Clinical efficacy of a revised dosage schedule of phenylbutazone in horses.
    The Veterinary record, 1983, Aug-20, Volume: 113, Issue:8

    Topics: Animals; Drug Administration Schedule; Female; Horse Diseases; Horses; Male; Phenylbutazone

1983
Phenylbutazone toxicosis in the foal.
    American journal of veterinary research, 1983, Volume: 44, Issue:8

    Topics: Animals; Barium Sulfate; Colonic Diseases; Diarrhea; Female; Gastric Mucosa; Gastroscopy; Horse Dise

1983
Renal papillary necrosis in horses after phenylbutazone and water deprivation.
    Veterinary pathology, 1983, Volume: 20, Issue:5

    Topics: Animals; Horse Diseases; Horses; Kidney; Kidney Papillary Necrosis; Phenylbutazone; Time Factors; Wa

1983
Facial and vestibulocochlear nerve disease in six horses.
    Journal of the American Veterinary Medical Association, 1983, Nov-15, Volume: 183, Issue:10

    Topics: Ampicillin; Animals; Chloramphenicol; Cochlear Nerve; Facial Paralysis; Female; Horse Diseases; Hors

1983
Renal medullary crest necrosis associated with phenylbutazone therapy in horses.
    Veterinary pathology, 1983, Volume: 20, Issue:6

    Topics: Animals; Female; Horse Diseases; Horses; Kidney Medulla; Kidney Papillary Necrosis; Male; Phenylbuta

1983
Effects of toxic doses of phenylbutazone in ponies.
    American journal of veterinary research, 1983, Volume: 44, Issue:12

    Topics: Administration, Oral; Animals; Gastrointestinal Diseases; Horse Diseases; Horses; Injections, Intrav

1983
Paste preparation of phenylbutazone.
    The Veterinary record, 1983, Aug-13, Volume: 113, Issue:7

    Topics: Animals; Dose-Response Relationship, Drug; Horse Diseases; Horses; Ointments; Phenylbutazone; Powder

1983
Phenylbutazone toxicosis in the horse: a clinical study.
    Journal of the American Veterinary Medical Association, 1984, Mar-15, Volume: 184, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Colon; Female; Horse Diseases; Horses; Hypoproteinemia;

1984
Vascular pathology in phenylbutazone intoxicated horses.
    The Cornell veterinarian, 1984, Volume: 74, Issue:3

    Topics: Animals; Horse Diseases; Horses; Male; Phenylbutazone; Vascular Diseases; Veins

1984
Therapeutic effect of phenylbutazone on experimental acute Escherichia coli endotoxemia in ponies.
    American journal of veterinary research, 1981, Volume: 42, Issue:1

    Topics: Animals; Blood Glucose; Carbon Dioxide; Endotoxins; Escherichia coli; Glucuronidase; Hematocrit; Hor

1981
Effects of large doses of phenylbutazone administration to horses.
    American journal of veterinary research, 1983, Volume: 44, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Gastric Mucosa; G

1983
Biochemical and haematological effects of a revised dosage schedule of phenylbutazone in horses.
    The Veterinary record, 1983, Jun-25, Volume: 112, Issue:26

    Topics: Animals; Drug Administration Schedule; Hematologic Tests; Horse Diseases; Horses; Ointments; Phenylb

1983
Studies on a new paste preparation of phenylbutazone.
    The Veterinary record, 1983, Jun-25, Volume: 112, Issue:26

    Topics: Absorption; Animals; Biological Availability; Horse Diseases; Horses; Kinetics; Ointments; Phenylbut

1983
Equine ulcerative lymphangitis caused by Pasteurella hemolytica (2 case reports).
    Veterinary medicine, small animal clinician : VM, SAC, 1981, Volume: 76, Issue:9

    Topics: Animals; Chloramphenicol; Furosemide; Horse Diseases; Horses; Lymphangitis; Male; Pasteurella Infect

1981
Two cases of Fusarium keratomycosis in the horse.
    The Veterinary record, 1982, May-29, Volume: 110, Issue:22

    Topics: Animals; Cautery; Corneal Ulcer; Fusarium; Horse Diseases; Horses; Male; Mycoses; Natamycin; Phenylb

1982
Paste formulation of phenylbutazone.
    The Veterinary record, 1982, Oct-09, Volume: 111, Issue:15

    Topics: Animals; Horse Diseases; Horses; Ointments; Phenylbutazone

1982
Science and the administration of phenylbutazone.
    Equine veterinary journal, 1981, Volume: 13, Issue:3

    Topics: Animals; Horse Diseases; Horses; Phenylbutazone

1981
Pharmacokinetics of phenylbutazone and its metabolites in the horse.
    Equine veterinary journal, 1981, Volume: 13, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Female; Horse Diseases; Horses; Kinetics; Lameness, Animal;

1981
Phenylbutazone toxicosis in equidae: a biochemical and pathophysiological study.
    American journal of veterinary research, 1981, Volume: 42, Issue:10

    Topics: Animals; Blood Proteins; Blood Urea Nitrogen; Cecum; Colon; Extracellular Space; Female; Horse Disea

1981
Non-steroidal anti-inflammatory agents in the horse.
    In practice, 1981, Volume: 3, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Clonixin; Horse Diseases; Horses; Inflammation; Meclofenamic Acid

1981
Phenylbutazone toxicity in ponies.
    The Veterinary record, 1980, Jan-19, Volume: 106, Issue:3

    Topics: Animals; Gastrointestinal Diseases; Horse Diseases; Horses; Hypoproteinemia; Phenylbutazone; Protein

1980
AVMA/Practice Group perspectives: use of drug labels in the prescription of antimicrobial therapy. Representing the American Association of Equine Practitioners (AAEP).
    Journal of the American Veterinary Medical Association, 1995, Oct-01, Volume: 207, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cephalosporins; Clonixin; D

1995
Effects of concurrent administration of phenylbutazone and flunixin meglumine on pharmacokinetic variables and in vitro generation of thromboxane B2 in mares.
    American journal of veterinary research, 1993, Volume: 54, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Drug Interactions; Female; Horse Disease

1993
Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses.
    Journal of the American Veterinary Medical Association, 1993, Jan-01, Volume: 202, Issue:1

    Topics: Animals; Anorexia; Blood Proteins; Clonixin; Female; Gastric Mucosa; Gastroscopy; Horse Diseases; Ho

1993
Clostridium difficile associated with typhlocolitis in an adult horse.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 1993, Volume: 5, Issue:1

    Topics: Animals; Antidiarrheals; Cecal Diseases; Cecum; Clostridioides difficile; Colitis; Diarrhea; Horse D

1993
Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse.
    Equine veterinary journal, 1995, Volume: 27, Issue:4

    Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases;

1995
Infection of the intertubercular bursa in horses: four cases (1978-1991).
    Journal of the American Veterinary Medical Association, 1996, May-01, Volume: 208, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Drug Therapy, Combination; Forelimb; Hor

1996
Descriptive epidemiological study of equine laminitis.
    Equine veterinary journal, 1995, Volume: 27, Issue:5

    Topics: Acepromazine; Acute Disease; Administration, Topical; Age Factors; Animals; Anti-Inflammatory Agents

1995
Pulmonary vascular pressures of strenuously exercising thoroughbreds after administration of phenylbutazone.
    American journal of veterinary research, 1996, Volume: 57, Issue:9

    Topics: Animals; Blood Pressure; Female; Heart Rate; Hemorrhage; Horse Diseases; Horses; Hypertension, Pulmo

1996
The effect of drugs used in the treatment of osteoarthrosis on stromelysin (proteoglycanase) of equine synovial cell origin.
    Equine veterinary journal. Supplement, 1988, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Clonixin;

1988
Evaluation of sodium hyaluronate therapy in induced septic arthritis in the horse.
    Equine veterinary journal. Supplement, 1992, Issue:11

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Cart

1992
Antagonism of endotoxin-induced disruption of equine bowel motility by flunixin and phenylbutazone.
    Equine veterinary journal. Supplement, 1989, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Colon; Dose-Response Relationship, Drug;

1989
Cervical diskospondylitis in two horses.
    Australian veterinary journal, 1997, Volume: 75, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cervical Vertebrae; Diagnosis, Differential; Horse

1997
Infectious temporomandibular joint disease in the horse: computed tomographic diagnosis and treatment of two cases.
    The Veterinary record, 1997, Aug-16, Volume: 141, Issue:7

    Topics: Ampicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Horse Diseases; Horses; Male

1997
Reconstruction of the jugular vein in horses with post thrombophlebitis stenosis using saphenous vein graft.
    Equine veterinary journal, 1998, Volume: 30, Issue:3

    Topics: Ampicillin; Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants;

1998
Medical management of urinary calculi in a stallion with breeding dysfunction.
    Journal of the American Veterinary Medical Association, 1998, Sep-15, Volume: 213, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Anti-Inflamma

1998
Renal medullary rim sign in 2 adult quarter horses.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1998, Volume: 39, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Kidney Diseases; Kidney Me

1998
Partial phallectomy to treat priapism in a horse.
    Australian veterinary journal, 1999, Volume: 77, Issue:3

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Anti-Infective Agents, Urinary; Anti-Inflamma

1999
[Navicular disease in the hind limb of a Warmblood horse].
    Tijdschrift voor diergeneeskunde, 1999, Sep-15, Volume: 124, Issue:18

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Female; Foot

1999
Ulceration and stricture of the right dorsal colon after phenylbutazone administration in four horses.
    Australian veterinary journal, 1999, Volume: 77, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Constriction, Pathologic; Fatal

1999
Effects of phenylbutazone on bone activity and formation in horses.
    American journal of veterinary research, 2000, Volume: 61, Issue:5

    Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Bone Density; Bone R

2000
Laparoscopic intra-abdominal ligation of the testicular artery following castration in a horse.
    Journal of the American Veterinary Medical Association, 2000, May-15, Volume: 216, Issue:10

    Topics: Animals; Anti-Infective Agents, Urinary; Anti-Inflammatory Agents, Non-Steroidal; Arteries; Blood Tr

2000
Questions duration of treatment with phenylbutazone.
    American journal of veterinary research, 2000, Volume: 61, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Diseases; Bone Remodeling; Horse Diseases; Ho

2000
Laminar microvascular flow, measured by means of laser Doppler flowmetry, during the prodromal stages of black walnut-induced laminitis in horses.
    American journal of veterinary research, 2000, Volume: 61, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Temperature; Foot Diseases; F

2000
Treatment of granular cell tumor via complete right lung resection in a horse.
    Journal of the American Veterinary Medical Association, 2000, Nov-15, Volume: 217, Issue:10

    Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Broncho

2000
Fistulation of the auditory tube diverticulum (guttural pouch) with a neodymium:yttrium-aluminum-garnet laser for treatment of chronic empyema in two horses.
    Journal of the American Veterinary Medical Association, 2001, Feb-01, Volume: 218, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dexamethasone; Ear Diseases; Empy

2001
Osteomyelitis of the sustentaculum tali in horses: 10 cases (1992-1998).
    Journal of the American Veterinary Medical Association, 2001, Aug-01, Volume: 219, Issue:3

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Debridement; Female; Follow

2001
Treatment and prognosis for cunean tendon bursitis-tarsitis of Standardbred horses.
    Journal of the American Veterinary Medical Association, 1979, Nov-15, Volume: 175, Issue:10

    Topics: Animals; Bursitis; Horse Diseases; Horses; Methylprednisolone; Phenylbutazone; Prognosis; Tendinopat

1979
Phenylbutazone toxicity in ponies.
    The Veterinary record, 1979, Aug-18, Volume: 105, Issue:7

    Topics: Animals; Horse Diseases; Horses; Phenylbutazone

1979
Phenylbutazone toxicity in ponies.
    The Veterinary record, 1979, Jul-14, Volume: 105, Issue:2

    Topics: Administration, Oral; Animals; Horse Diseases; Horses; Injections, Intravenous; Intestines; Phenylbu

1979
Navicular disease in the horse: risk factors, radiographic changes, and response to therapy.
    Journal of the American Veterinary Medical Association, 1977, Jan-15, Volume: 170, Issue:2

    Topics: Animals; Bursitis; Female; Foot Diseases; Forelimb; Horse Diseases; Horses; Male; Osteitis; Phenylbu

1977
Arthroscopic removal of a palmar radial osteochondroma causing carpal canal syndrome in a horse.
    Journal of the American Veterinary Medical Association, 1992, Oct-15, Volume: 201, Issue:8

    Topics: Animals; Arthroscopy; Bone Neoplasms; Carpal Tunnel Syndrome; Carpus, Animal; Chemotherapy, Adjuvant

1992
Anti-inflammatory drugs inhibit degradation of equine synovial fluid induced by free radicals.
    Australian veterinary journal, 1991, Volume: 68, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dimethyl Sulfox

1991
Poisoning with equine phenylbutazone in a racetrack worker.
    Annals of emergency medicine, 1991, Volume: 20, Issue:2

    Topics: Acute Kidney Injury; Adult; Animals; Chemical and Drug Induced Liver Injury; Coma; Dogs; Drug Overdo

1991
Use of transendoscopic contact neodymium:yttrium aluminum garnet laser to drain dorsal epiglottic abscesses in two horses.
    Journal of the American Veterinary Medical Association, 1991, May-15, Volume: 198, Issue:10

    Topics: Abscess; Animals; Epiglottis; Female; Horse Diseases; Horses; Laryngoscopy; Laser Therapy; Male; Pen

1991
Treatment of right dorsal ulcerative colitis in a horse.
    Journal of the American Veterinary Medical Association, 1990, Feb-01, Volume: 196, Issue:3

    Topics: Anastomosis, Surgical; Animals; Colectomy; Colitis, Ulcerative; Horse Diseases; Horses; Male; Phenyl

1990
The isoelectric focusing properties of serum alkaline phosphatase in disease and following prednisolone and phenylbutazone administration in the horse.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1990, Volume: 54, Issue:1

    Topics: Alkaline Phosphatase; Animals; Female; Horse Diseases; Horses; Intestinal Diseases; Isoelectric Focu

1990
Copper salicylate and copper phenylbutazone as topically applied anti-inflammatory agents in the rat and horse.
    Journal of veterinary pharmacology and therapeutics, 1990, Volume: 13, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dimethyl Sul

1990
The effects of phenylbutazone on the morphology and prostaglandin concentrations of the pyloric mucosa of the equine stomach.
    Veterinary pathology, 1990, Volume: 27, Issue:4

    Topics: Animals; Gastric Mucosa; Horse Diseases; Horses; Microscopy, Electron; Phenylbutazone; Prostaglandin

1990
The protective effects of sucralfate and ranitidine in foals experimentally intoxicated with phenylbutazone.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1989, Volume: 53, Issue:2

    Topics: Animals; Animals, Newborn; Blood Chemical Analysis; Digestive System Diseases; Duodenum; Hematologic

1989
Horse pill ("bute") hemorrhage.
    Journal of clinical gastroenterology, 1988, Volume: 10, Issue:2

    Topics: Adult; Animals; Gastrointestinal Hemorrhage; Horse Diseases; Horses; Humans; Male; Phenylbutazone; S

1988
Septicemic salmonellosis and suspected phenylbutazone toxicosis in an aged pony.
    Journal of the American Veterinary Medical Association, 1988, Feb-15, Volume: 192, Issue:4

    Topics: Animals; Horse Diseases; Horses; Male; Peptic Ulcer; Phenylbutazone; Salmonella Infections, Animal;

1988
Effects of a phenylbutazone paste in ponies: model of acute nonimmune inflammation.
    American journal of veterinary research, 1986, Volume: 47, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Temperature; Dinoprostone; Disease Models, Animal; Exuda

1986
Healing of experimentally induced corneal ulcers in horses.
    American journal of veterinary research, 1987, Volume: 48, Issue:3

    Topics: Animals; Atropine; Chloramphenicol; Corneal Ulcer; Female; Horse Diseases; Horses; Male; Ointments;

1987
Comparison of various treatments for experimentally induced equine infectious arthritis.
    American journal of veterinary research, 1987, Volume: 48, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Arthritis, Infectious; Arthrography; Cartilage

1987
Experimentally induced phenylbutazone toxicosis in ponies: description of the syndrome and its prevention with synthetic prostaglandin E2.
    American journal of veterinary research, 1985, Volume: 46, Issue:8

    Topics: Animals; Dinoprostone; Female; Gastrointestinal Diseases; Horse Diseases; Horses; Intestinal Mucosa;

1985
[An undesirable drug interaction in horses? Complications which can occur during the administration of coumarin derivatives and phenylbutazone].
    Tijdschrift voor diergeneeskunde, 1985, Aug-15, Volume: 110, Issue:15-16

    Topics: Animals; Coumarins; Dogs; Drug Interactions; Horse Diseases; Horses; Phenylbutazone; Vitamin K

1985
Suspected non-steroidal anti-inflammatory drug toxicity in a horse.
    The Veterinary record, 1985, Nov-30, Volume: 117, Issue:22

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Butylscopolammonium Bromide; Dipyrone; Drug Combinat

1985
Uses and misuses of anti-inflammatory drugs in racehorses. 1.
    Equine veterinary journal, 1972, Apr-05, Volume: 4, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Glucocorticoids;

1972
A clinician's views on the use and misuse of phenylbutazone.
    Equine veterinary journal, 1972, Apr-05, Volume: 4, Issue:2

    Topics: Animals; Horse Diseases; Horses; Humans; Movement Disorders; Phenylbutazone; Substance-Related Disor

1972
Uses and misuses of anti-inflammatory drus in racehorses. II.
    Equine veterinary journal, 1972, Apr-05, Volume: 4, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Horse Diseases; Horses; Humans; Movement Disorders

1972
[Study of processes leading to an increase of pulmonary marginal distance in the horse].
    Schweizer Archiv fur Tierheilkunde, 1973, Volume: 115, Issue:9

    Topics: Animals; Auscultation; Bronchitis; Horse Diseases; Horses; Injections, Intravenous; Lung; Percussion

1973