Compounds > phenylbutazone
Page last updated: 2024-11-02

phenylbutazone and Dermatitis Medicamentosa

phenylbutazone has been researched along with Dermatitis Medicamentosa in 56 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"A double-blind cross-over study using a double placebo technique was employed to compare the effectiveness of daily alclofenac 3 g and phenylbutazone 300 mg in rheumatoid arthritis."9.04A double blind trial to assess the value of alclofenac compared with phenylbutazone in the management of rheumatoid arthritis. ( Chamberlain, MA; Wright, V, 1975)
"Two patients had phenylbutazone-induced systemic vasculitis syndrome."7.67Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. ( Dobbie, JW; Jones, JM; Leung, AC; McLay, A, 1985)
"A double-blind cross-over study using a double placebo technique was employed to compare the effectiveness of daily alclofenac 3 g and phenylbutazone 300 mg in rheumatoid arthritis."5.04A double blind trial to assess the value of alclofenac compared with phenylbutazone in the management of rheumatoid arthritis. ( Chamberlain, MA; Wright, V, 1975)
"Two patients had phenylbutazone-induced systemic vasculitis syndrome."3.67Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. ( Dobbie, JW; Jones, JM; Leung, AC; McLay, A, 1985)
"Eighteen patients with definite ankylosing spondylitis were treated with 3 to 4 g."2.64Alclofenac in ankylosing spondylitis. ( Bulgen, DY; Hazleman, BL, 1975)
"Phenylbutazone-induced sialadenitis is rare and presents unrecognized adverse effects that may be associated with a systemic reaction."1.35[Sweet's syndrome and phenylbutazone-induced sialadenitis]. ( Girardin, P; Humbert, P; Levang, J; Muller, P, 2008)
"Those with toxic epidermal necrolysis had 100% mortality."1.27Drug eruptions from phenylbutazone in Jamu. ( Giam, YC; Lim, A; Tan, T; Tham, SN, 1986)
"Pericarditis was the most severe manifestation, and in one patient, this required corticosteroid therapy."1.26Sialadenitis and systemic reaction associated with phenylbutazone. ( Speed, BR; Spelman, DW, 1982)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199049 (87.50)18.7374
1990's3 (5.36)18.2507
2000's2 (3.57)29.6817
2010's2 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valade, S1
Toledano, C1
Tiev, K1
Gain, M1
Josselin, L1
Cabane, J1
Kettaneh, A1
Toms-Whittle, LM1
Hickey, JR1
Buckley, DA1
Schmutz, JL1
Barbaud, A1
Trechot, P1
CHARET, R1
SIEGEL, I1
HASSELMANN, CM1
PARMAR, IS1
BEHL, PN1
KINDERMANN, A1
MUSUMECI, V1
GEORGIEVA, S1
BOIANOV, L1
DIMITROVA, II1
KAPNILOV, S1
BONCINELLI, U1
VACCARI, R1
VAS, CJ1
TERZANI, A1
LAMY, P1
BEUREY, J1
ANTHOINE, D1
VADOT, J1
JACQUIN, B1
BERTHEAU, JM1
HARTMAN, DL1
DICKEY, RF1
MANGANOTTI, G1
SILVESTRI, U1
BILANCIA, A1
Levang, J1
Muller, P1
Girardin, P1
Humbert, P1
Speed, BR1
Spelman, DW1
Robertson, C1
Innes, S1
Paton, J1
Valsecchi, R1
Tornaghi, A1
Falgheri, G1
Rossi, A1
Cainelli, T1
Harris, PG1
Kerre, S1
Busschots, A1
Dooms-Goossens, A1
Walchner, M1
Rueff, F1
Przybilla, B1
Millard, LG1
Gadzhiev, RG1
Davardarova, MM1
Haslock, I1
Burkinshaw, L1
Berry, DJ1
Donovan, B1
Wright, V2
Kaaber, K1
Thormann, J1
Farkas, J1
Dobozy, A1
Hunyadi, J1
Kenderessy, AS1
Fasching, U1
Eberl, R1
Hertzenberg, S1
Krook, G2
Vooys, RC1
van Ketel, WG1
van Joost, T2
Hoigné, R1
Chamberlain, MA1
Bulgen, DY1
Hazleman, BL1
Nayar, M1
Ng, SK1
Giam, YC1
Tham, SN1
Tan, T1
Lim, A1
Kashchenko, VB1
Kozhukhar', GS1
Fernández de Corres, L1
Bernaola, G1
Lobera, T1
Leanizbarrutia, I1
Muñoz, D1
Leung, AC1
McLay, A1
Dobbie, JW1
Jones, JM1
Littlejohns, DW1
Assem, ES1
Kennedy, CT1
Thorne, N1
Kinsella, TD1
MacKenzie, KR1
Kim, SO1
Johnson, LG1
Paschoud, JM1
Ramakumar, L1
Goyal, BG1
Raith, W1
Königstein, RP1
Vlcek, F1
Almeyda, J1
Baker, H1
Visintini, E1
Klinefelter, HF1
Louis, P1
Asghar, SS1
Cormane, RH1
Willoughby, DA1
Walters, MN1
Spector, WG1

Reviews

3 reviews available for phenylbutazone and Dermatitis Medicamentosa

ArticleYear
[CONTRIBUTION TO THE STUDY OF THE LYELL SYNDROME].
    Archivio italiano di dermatologia, venereologia, e sessuologia, 1964, Volume: 32

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoid; D

1964
Skin reactions to systemic drug therapy.
    The Practitioner, 1973, Volume: 211, Issue:265

    Topics: Antitubercular Agents; Barbiturates; Chloramphenicol; Contraceptives, Oral; Corticosterone; Drug Eru

1973
Drug reactions. XII. Cutaneous reactions to anti-rheumatic drugs.
    The British journal of dermatology, 1970, Volume: 83, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Drug Eruptions; Edema; Female; Gold; Humans; Indomethacin; Lymphade

1970

Trials

5 trials available for phenylbutazone and Dermatitis Medicamentosa

ArticleYear
Some studies of feprazone.
    Rheumatology and rehabilitation, 1976, Volume: 15, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topi

1976
[Sulindac: Clinical test of a new antiinflammatory agent in rheumatoid arthritis (author's transl)].
    Wiener klinische Wochenschrift. Supplementum, 1976, Volume: 59

    Topics: Adult; Aged; Alopecia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzylidene Compoun

1976
A double blind trial to assess the value of alclofenac compared with phenylbutazone in the management of rheumatoid arthritis.
    Annals of the rheumatic diseases, 1975, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Eruptions; Female; Ga

1975
Alclofenac in ankylosing spondylitis.
    Current medical research and opinion, 1975, Volume: 3, Issue:5

    Topics: Adult; Blood Sedimentation; Clinical Trials as Topic; Drug Eruptions; Female; Humans; Indomethacin;

1975
Evaluation of indomethacin by a controlled, cross-over technique in 30 patients with ankylosing spondylitis.
    Canadian Medical Association journal, 1967, Jun-03, Volume: 96, Issue:22

    Topics: Alkaline Phosphatase; Anemia, Hypochromic; Aspartate Aminotransferases; Aspirin; Central Nervous Sys

1967

Other Studies

48 other studies available for phenylbutazone and Dermatitis Medicamentosa

ArticleYear
[DRESS syndrome caused by phenylbutazone].
    La Revue de medecine interne, 2009, Volume: 30, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Eosinophilia; Female; Humans; Middle Aged;

2009
Bullous eruption of the lower limbs following equine phenylbutazone injection.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Female; Horses; Humans; Lower Extr

2010
[Phenylbutazone and DRESS syndrome].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Azithromycin; Diagnosis,

2010
Unusual reaction following use of phenylbutazone (butazolidin).
    Journal of the American Medical Association, 1953, Feb-14, Volume: 151, Issue:7

    Topics: Adrenocorticotropic Hormone; Analgesics; Chlortetracycline; Drug Eruptions; Oral Ulcer; Phenylbutazo

1953
[Severe side-effects of irgapyrin, with fatal exfoliative erythroderma].
    Medizinische Klinik, 1953, May-08, Volume: 48, Issue:19

    Topics: Aminopyrine; Analgesics; Dermatitis, Exfoliative; Drug Combinations; Drug Eruptions; Humans; Phenylb

1953
Eczematoid dermatitis following butazolidine injections.
    Journal of the Indian Medical Association, 1957, May-16, Volume: 28, Issue:10

    Topics: Drug Eruptions; Humans; Injections; Phenylbutazone

1957
[Vascular allergid due to butalidon and hazards of its combined used with athrombon (phenylindandione)].
    Dermatologische Wochenschrift, 1961, Feb-18, Volume: 143

    Topics: Drug Eruptions; Humans; Hypersensitivity; Immune System Diseases; Phenindione; Phenylbutazone

1961
[On the Lyell syndrome].
    Minerva dermatologica, 1962, Volume: 37

    Topics: Drug Eruptions; Penicillins; Phenylbutazone; Stevens-Johnson Syndrome; Streptomycin

1962
[A new superacute drug syndrome (necrolysis epidermalis toxica, Lyell's syndrome)].
    Suvremenna meditsina, 1962, Volume: 13(8)

    Topics: Aminopyrine; Drug Eruptions; Humans; Penicillins; Phenylbutazone; Stevens-Johnson Syndrome; Streptom

1962
[Lyell's syndrome].
    Minerva dermatologica, 1963, Volume: 38

    Topics: Adrenal Cortex Hormones; Aminopyrine; Anti-Bacterial Agents; Drug Eruptions; Humans; Phenylbutazone;

1963
An unusual complication of phenylbutazone therapy--toxic epidermal necrolysis.
    Postgraduate medical journal, 1963, Volume: 39

    Topics: Drug Eruptions; Humans; Phenylbutazone; Stevens-Johnson Syndrome

1963
[DAMAGE FROM THERAPY].
    La Clinica terapeutica, 1963, Oct-15, Volume: 27

    Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompati

1963
[LYELL'S SYNDROME. (APROPOS OF A RECENT CASE)].
    Annales medicales de Nancy, 1964, Volume: 3

    Topics: Diagnosis, Differential; Drug Eruptions; Penicillins; Phenylbutazone; Stevens-Johnson Syndrome; Toxi

1964
PHOTODERMATITIS INDUCED BY DRUGS. II. PHOTODERMATITIS MEDICAMENTOSA.
    Skin, 1964, Volume: 3

    Topics: Anti-Bacterial Agents; Benzoates; Chlorothiazide; Diphenhydramine; Drug Eruptions; Estrogens; Geriat

1964
[CONTRIBUTION TO THE STUDY OF CUTANEOUS REACTIVITY TO SOME DRUGS].
    Archivio italiano di dermatologia, venereologia, e sessuologia, 1965, Volume: 33

    Topics: Aminopyrine; Antipyrine; Drug Eruptions; Phenylbutazone; Skin Tests; Toxicology

1965
[Sweet's syndrome and phenylbutazone-induced sialadenitis].
    Annales de dermatologie et de venereologie, 2008, Volume: 135, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Female; Humans; Middle Aged; Phenylbutazone

2008
Sialadenitis and systemic reaction associated with phenylbutazone.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:3

    Topics: Adult; Drug Eruptions; Female; Fever; Humans; Male; Middle Aged; Pericarditis; Phenylbutazone; Pleur

1982
Renal failure complicating feprazone treatment.
    Human toxicology, 1981, Volume: 1, Issue:1

    Topics: Acute Kidney Injury; Aged; Drug Eruptions; Feprazone; Humans; Male; Phenylbutazone

1981
Drug reaction from oxyphenbutazone.
    Contact dermatitis, 1983, Volume: 9, Issue:5

    Topics: Aged; Cross Reactions; Drug Eruptions; Humans; Male; Oxyphenbutazone; Phenylbutazone; Suppositories

1983
A monitored-release study of methrazone in general practice.
    The Journal of international medical research, 1980, Volume: 8, Issue:4

    Topics: Adult; Aged; Arthritis, Rheumatoid; Central Nervous System Diseases; Drug Eruptions; Drug Interactio

1980
Erythema-multiforme-like contact dermatitis due to phenylbutazone.
    Contact dermatitis, 1995, Volume: 33, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Allergic Contact; Diagnosis, Differential

1995
Delayed-type hypersensitivity to mofebutazone underlying a severe drug reaction.
    Contact dermatitis, 1997, Volume: 36, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Eczema; Female; Humans; Hypersensitivity, D

1997
A haemorrhagic bullous eruption of the hands caused by phenylbutazone: a report of 3 cases.
    Acta dermato-venereologica, 1977, Volume: 57, Issue:1

    Topics: Adult; Drug Eruptions; Female; Hand Dermatoses; Hemorrhage; Humans; Male; Middle Aged; Phenylbutazon

1977
[Effectiveness of butadione ointment in some dermatoses].
    Vestnik dermatologii i venerologii, 1975, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Aged; Child; Dermatitis; Drug Eruptions; Drug Evaluation; Eczema;

1975
[Contact allergy after phenylbutazone ointment. 4 cases and a review].
    Ugeskrift for laeger, 1976, Jul-12, Volume: 138, Issue:29

    Topics: Dermatitis, Atopic; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Midd

1976
[Balanitis medicamentosa erythematosa, bullosa, erosiva et ulcerosa combustiformis as manifestation of a fixed medicamentous exanthema].
    Dermatologische Monatschrift, 1976, Volume: 162, Issue:3

    Topics: Adult; Aminopyrine; Balanitis; Drug Eruptions; Humans; Male; Middle Aged; Phenylbutazone; Tetracycli

1976
[The lymphocyte transformation test in drug hypersensitivities].
    Zeitschrift fur Hautkrankheiten, 1976, May-01, Volume: 51, Issue:09

    Topics: Anti-Bacterial Agents; Antibody Formation; Cell Migration Inhibition; Diazepam; Drug Eruptions; Huma

1976
[Phenylbutazone ointment. Be sure of contraindications].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1977, Jan-30, Volume: 97, Issue:3

    Topics: Drug Eruptions; Humans; Ointments; Phenylbutazone

1977
Contact sensitivity to oxyphenbutazone (Tanderil) and cross-sensitivity to phenylbutazone (Butazolidin).
    Contact dermatitis, 1975, Volume: 1, Issue:4

    Topics: Dermatitis, Contact; Drug Eruptions; Female; Humans; Middle Aged; Ointments; Oxyphenbutazone; Phenyl

1975
Contact sensitivity to oxyphenbutazone (Tanderil) and cross-sensitivity to phenylbutazone (Butazolidine)
    Contact dermatitis, 1975, Volume: 1, Issue:6

    Topics: Drug Eruptions; Humans; Male; Middle Aged; Oxyphenbutazone; Patch Tests; Phenylbutazone

1975
Allergic drug eruption from pyrazolone compounds.
    Contact dermatitis, 1977, Volume: 3, Issue:1

    Topics: Cross Reactions; Drug Eruptions; Female; Humans; Middle Aged; Patch Tests; Phenylbutazone

1977
[The skin as a signal organ].
    Nederlands tijdschrift voor geneeskunde, 1977, Mar-12, Volume: 121, Issue:11

    Topics: Cathartics; Drug Eruptions; Erysipelas; Erythromycin; Female; Humans; Male; Middle Aged; Penicillin

1977
[Diagnostic problems in drug hypersensitivity].
    Anasthesiologische und intensivmedizinische Praxis, 1977, Volume: 14, Issue:1

    Topics: Agranulocytosis; Ampicillin; Anaphylaxis; Anemia, Hemolytic; Aspirin; Asthma; Drug Eruptions; Drug H

1977
Contact sensitivity to phenylbutazone (Butazolidine) cream.
    Contact dermatitis, 1991, Volume: 25, Issue:4

    Topics: Acute Disease; Administration, Cutaneous; Adult; Dermatitis, Contact; Drug Eruptions; Female; Humans

1991
Drug eruptions from phenylbutazone in Jamu.
    Annals of the Academy of Medicine, Singapore, 1986, Volume: 15, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Dermatitis, Exfoliative; Drug Eruptions; Female; Huma

1986
[A case of dermatitis medicamentosa].
    Vrachebnoe delo, 1986, Issue:3

    Topics: Aged; Dermatitis, Contact; Drug Eruptions; Female; Humans; Phenylbutazone; Self Medication

1986
Allergy from pyrazoline derivatives.
    Contact dermatitis, 1986, Volume: 14, Issue:4

    Topics: Drug Combinations; Drug Eruptions; Humans; Male; Middle Aged; Patch Tests; Phenylbutazone; Piperazin

1986
Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Acute Kidney Injury; Aged; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Glomerulonep

1985
Immunological evidence of two forms of allergy to pyrazolone drugs.
    Rheumatology and rehabilitation, 1973, Volume: 12, Issue:2

    Topics: Aged; Drug Eruptions; Drug Hypersensitivity; Female; Fever; Histamine Release; Humans; Immunoglobuli

1973
[Vasculitis allergica cutis caused by phenylbutazone].
    Dermatologica, 1966, Volume: 133, Issue:1

    Topics: Aged; Aminopyrine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Oxyphen

1966
Iragapyrin toxicity.
    Indian journal of pediatrics, 1967, Volume: 34, Issue:229

    Topics: Aminopyrine; Child, Preschool; Drug Eruptions; Gangrene; Humans; Male; Phenylbutazone; Tongue Diseas

1967
[Phenylbutazone-exanthema with thrombocytic and myeloid reaction].
    Dermatologische Wochenschrift, 1967, May-20, Volume: 153, Issue:20

    Topics: Bone Marrow; Drug Eruptions; Drug Hypersensitivity; Exanthema; Humans; Male; Middle Aged; Phenylbuta

1967
[Electrometric demonstration of hypersensitivity to antirheumatic drugs].
    Archiv fur klinische und experimentelle Dermatologie, 1970, Volume: 237, Issue:1

    Topics: Anti-Inflammatory Agents; Antimalarials; Drug Eruptions; Gold; Humans; Hydroxychloroquine; Methods;

1970
[Iatrogenic damage in therapy with phenylbutazone].
    Minerva medica, 1971, Feb-24, Volume: 62, Issue:16

    Topics: Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Drug Eruptions; Endocrine System Di

1971
Primary fibrositis and its treatment with the pyrazolone derivatives, butazolidin and tandearil.
    The Johns Hopkins medical journal, 1972, Volume: 130, Issue:5

    Topics: Adult; Age Factors; Diagnosis, Differential; Drug Eruptions; Edema; Female; Fibromyalgia; Humans; Ma

1972
[Etiologic diagnosis of fixed drug exanthemas].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, Apr-15, Volume: 47, Issue:8

    Topics: Barbiturates; Drug Eruptions; Drug Hypersensitivity; Exanthema; Humans; Phenacetin; Phenolphthaleins

1972
Skin reactions caused by phenylbutazone. Immunologic studies.
    Archives of dermatology, 1974, Volume: 110, Issue:6

    Topics: Complement Fixation Tests; Drug Eruptions; Fluorescent Antibody Technique; Humans; Immunoglobulin A;

1974
An analysis of the irritant action of dimethyl sulphoxide.
    The Journal of pathology and bacteriology, 1966, Volume: 91, Issue:1

    Topics: Animals; Capillary Permeability; Dimethyl Sulfoxide; Drug Eruptions; Histamine H1 Antagonists; Pheny

1966