phenylbutazone has been researched along with Chronic Disease in 67 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with chronic erythema nodosum of two years' duration, who did not respond to treatment with aspirin or with phenylbutazone therapy, had a dramatic response and improvement when treated with naproxen." | 7.66 | Control of chronic erythema nodosum with naproxen. ( Lehman, CW, 1980) |
| " These data suggest that ketoprofen at the dosage rate of 1." | 5.29 | Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. ( Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR, 1995) |
| " All these compounds proved to be effective against 12-O-tetradecanoylphorbol-13-acetate-induced ear edema in mice, although lacking activity against arachidonic acid-induced edema." | 3.70 | A glycosyl analogue of diacylglycerol and other antiinflammatory constituents from Inula viscosa. ( Gil, I; Giner, RM; Gómez, C; Máñez, S; Recio, MC; Ríos, JL; Waterman, PG, 1999) |
| "A patient with chronic erythema nodosum of two years' duration, who did not respond to treatment with aspirin or with phenylbutazone therapy, had a dramatic response and improvement when treated with naproxen." | 3.66 | Control of chronic erythema nodosum with naproxen. ( Lehman, CW, 1980) |
| " The study was instituted during the early evaluation of ketoprofen when the dosage of 100 mg/day was being tried; it is felt that a more significant result may possibly have emerged if the dosage had been the now recommended one of 150 mg/day." | 2.64 | Double-blind cross-over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip. ( Cardoe, N, 1976) |
| " These data suggest that ketoprofen at the dosage rate of 1." | 1.29 | Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse. ( Kamerling, SG; Keowen, ML; Owens, JG; Stanton, SR, 1995) |
| "Creatine is an aminoacid which has been found to posses anti-inflammatory activity." | 1.26 | Studies on the anti-inflammatory activity of creatine. ( Khanna, NK; Madan, BR, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (89.55) | 18.7374 |
| 1990's | 4 (5.97) | 18.2507 |
| 2000's | 3 (4.48) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Máñez, S | 1 |
| Recio, MC | 1 |
| Gil, I | 1 |
| Gómez, C | 1 |
| Giner, RM | 1 |
| Waterman, PG | 1 |
| Ríos, JL | 1 |
| SPIESS, H | 1 |
| BORRACHERO, J | 1 |
| DEL CARMEN SANCHEZ DE BORRACHERO, M | 1 |
| SIMON, SW | 1 |
| Xie, H | 1 |
| Colahan, P | 1 |
| Ott, EA | 1 |
| Adak, M | 1 |
| Gupta, JK | 1 |
| Mozziconacci, P | 1 |
| Hayem, F | 1 |
| Guy-Grand, D | 1 |
| Kirk, RM | 1 |
| Alessandrini, A | 1 |
| Gemini, R | 1 |
| Schlumpf, U | 1 |
| Wright, R | 1 |
| Adithan, C | 1 |
| Shashindran, CH | 1 |
| Gandhi, IS | 1 |
| Singh, DS | 1 |
| Balachandar, J | 1 |
| Lehman, CW | 1 |
| Owens, JG | 1 |
| Kamerling, SG | 1 |
| Stanton, SR | 1 |
| Keowen, ML | 1 |
| Slater, MR | 1 |
| Hood, DM | 1 |
| Carter, GK | 1 |
| Ritmeester, AM | 1 |
| Blevins, WE | 1 |
| Ferguson, DW | 1 |
| Adams, SB | 1 |
| Hawkins, JF | 1 |
| Frank, N | 1 |
| Sojka, JE | 1 |
| Levy, M | 1 |
| Kageyama, T | 1 |
| Emmerson, BT | 1 |
| Khanna, NK | 1 |
| Madan, BR | 1 |
| Cardoe, N | 1 |
| Sofia, RD | 1 |
| Wallace, S | 1 |
| Brodie, MJ | 1 |
| Dzieciuchowicz, L | 1 |
| Nowak, D | 1 |
| Ermalinskiĭ, AF | 1 |
| Balakin, AK | 1 |
| Iukhnovets, RA | 1 |
| Vedenina, RF | 1 |
| Levi, AJ | 1 |
| Sherlock, S | 1 |
| Walker, D | 1 |
| Holmes, B | 1 |
| Good, RA | 1 |
| Steiger, U | 1 |
| Ball, GV | 1 |
| Freeman, D | 1 |
| Ehrlich, GE | 1 |
| Bischoff, HP | 1 |
| Gormsen, J | 1 |
| Andersen, LA | 1 |
| Anylward, M | 1 |
| Davies, DB | 1 |
| Widmer, LK | 1 |
| Raps, E | 1 |
| Glaus, L | 1 |
| Rejholec, V | 1 |
| Pavelka, K | 1 |
| Susta, A | 1 |
| Vojtísek, O | 1 |
| Brémová, A | 1 |
| Kanková, D | 1 |
| Hándlová, D | 1 |
| Malecek, J | 1 |
| de Sèze, S | 1 |
| Dryll, A | 1 |
| Dreiser, R | 1 |
| Hartl, W | 1 |
| Otto, W | 2 |
| Häntzschel, H | 1 |
| Ravera, M | 1 |
| Raab, W | 1 |
| Moerth, C | 1 |
| Ipatova, NN | 1 |
| Martynov, SV | 1 |
| de Reus, HD | 1 |
| Tamisier, JN | 1 |
| Lamarche, M | 1 |
| Pourel, J | 1 |
| Louyot, P | 1 |
| Trnavský, K | 1 |
| Vykydal, M | 1 |
| Geller, J | 1 |
| Mikkelsen, WM | 1 |
| Robinson, WD | 1 |
| Sugiyama, T | 1 |
| Schmied, P | 1 |
| Van Rossum, P | 1 |
| Fallet, GH | 1 |
| Bossa, G | 1 |
| Giordano, M | 1 |
| Grant, NH | 1 |
| Rosenthale, ME | 1 |
| Alburn, HE | 1 |
| Singer, AC | 1 |
| Mathies, H | 1 |
| Ballabio, CB | 1 |
| Ligmière, GC | 1 |
| Famtiori, F | 1 |
| Tosi, S | 1 |
| Colombo, B | 1 |
| Burns, SL | 1 |
| Fernández del Vallado, P | 2 |
| Gijón Baños, J | 2 |
| Gálvez Failde, JM | 1 |
| Beltrán Gutiérrez, J | 1 |
| Leavesley, GM | 1 |
| Stenhouse, NS | 1 |
| Dougan, L | 1 |
| Woodliff, HJ | 1 |
| Roth, L | 1 |
| Chiriţă, P | 1 |
| Georgescu, L | 1 |
| Tudose, N | 1 |
| Ueno, R | 1 |
| Rebedea, D | 1 |
| Dragoncea, C | 1 |
| Bianco, I | 1 |
| Otto, H | 1 |
| Palmer, WL | 1 |
| Simpson, MR | 1 |
| Simpson, NR | 1 |
| Masheter, HC | 1 |
| Kuzell, WC | 1 |
| Scott, JT | 1 |
| Binder, E | 1 |
| Jiménez Roldán, A | 1 |
| Morcillo Hervás, C | 1 |
| Gálvez Failde, J | 1 |
6 reviews available for phenylbutazone and Chronic Disease
| Article | Year |
|---|---|
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe | 1982 |
Drug-induced chronic hepatitis.
Topics: Allopurinol; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Female; Granuloma | 1980 |
Drug control of gout and hyperuricaemia.
Topics: Allopurinol; Arthritis; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Naproxen; Phenylbut | 1978 |
Physiologic and biochemical basis for the treatment of gout and hyperuricemia.
Topics: Acute Disease; Adrenal Cortex Hormones; Arthritis; Chronic Disease; Colchicine; Glomerular Filtratio | 1969 |
[Determination of effects of drug therapy in chronic rheumatoid arthritis--problems in determination of therapeutic effects of anti-rheumatoid drugs].
Topics: Acetates; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Humans; Indomethacin; Ph | 1970 |
[The conservative treatment of chronic inflammatory rheumatism].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Anti-Inflammatory Agents; Antimalarials; Art | 1969 |
12 trials available for phenylbutazone and Chronic Disease
| Article | Year |
|---|---|
[Comparative clinical study of the efficacy of and tolerance for lysine para-isobutylphenyl propionate in parallel with indomethacin and pyrasanone].
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; I | 1980 |
Digital perfusion, evaluated scintigraphically, and hoof wall growth in horses with chronic laminitis treated with egg bar-heart bar shoeing and coronary grooving.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases; Hoof and C | 1998 |
Double-blind cross-over study of ketoprofen and phenylbutazone in patients with chronic osteoarthrosis of the hip.
Topics: Adult; Aged; Anti-Inflammatory Agents; Benzophenones; Chronic Disease; Clinical Trials as Topic; Fem | 1976 |
Phenylbutazone and isoniazid metabolism in patients with liver disease in relation to previous drug therapy.
Topics: Acetylesterase; Acute Disease; Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Barbit | 1968 |
[Comparison of a vitamin-containing and a vitamin-free phenylbutazone preparation in chronic degenerative spinal and joint diseases].
Topics: Chronic Disease; Drug Combinations; Drug Compounding; Humans; Joint Diseases; Phenylbutazone; Spinal | 1974 |
A double-blind crossover trial comparing a new antirheumatic agent alclofenac with phenylbutazone in chronic rheumatic disorders.
Topics: Adult; Aged; Allyl Compounds; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; | 1972 |
[Local treatment of leg disorders and chronic venous insufficiency. Double blind study of 55 patients].
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Dimethyl Sulfoxide; Humans; Leg; Male; Middl | 1972 |
[Analgesic effect of perclusone, measured with a pressure algometer in 50 patients with primary chronic polyarthritis].
Topics: Acetamides; Analgesics; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Drug Combi | 1972 |
Double-blind comparison of ibuprofen and phenylbutazone in a short-term treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzyl Compounds; Blood Sedimentation; Chronic Dise | 1973 |
[Results of clinical trials of calcium bucloxate (804 CB) in rheumatology].
Topics: Adult; Aged; Alanine Transaminase; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspar | 1974 |
A comparative trial of aloxiprin ('Palaprin Forte') and phenylbutazone ('Butazolidin').
Topics: Arthritis; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Pain; Pheny | 1968 |
[Determination of effects of drug therapy in chronic rheumatoid arthritis--problems in determination of therapeutic effects of anti-rheumatoid drugs].
Topics: Acetates; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Humans; Indomethacin; Ph | 1970 |
50 other studies available for phenylbutazone and Chronic Disease
| Article | Year |
|---|---|
A glycosyl analogue of diacylglycerol and other antiinflammatory constituents from Inula viscosa.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 1999 |
[On roentgenological bone changes in primary chronic arthritis in childhood and their reversibility].
Topics: Arthritis, Gouty; Bone and Bones; Chronic Disease; Cortisone; Humans; Phenylbutazone | 1959 |
[Treatment of chronic gouty arthritis with Anturan (G-28315)].
Topics: Arthritis, Gouty; Chronic Disease; Gout; Phenylbutazone; Sulfinpyrazone | 1962 |
Evaluation of anti-inflammatory agents in the treatment of chronic infectious asthma.
Topics: Anti-Inflammatory Agents; Asthma; Chronic Disease; Communicable Diseases; Phenylbutazone; Prednisolo | 1962 |
Evaluation of electroacupuncture treatment of horses with signs of chronic thoracolumbar pain.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Chronic Disease; Electroacupuncture; Fe | 2005 |
Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological system.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Calotropis; Chronic Disease; Edema; Home | 2006 |
[Chronic oligoarthritis in children].
Topics: Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Glucocorticoids; Humans; Hydr | 1967 |
Factors determining the site of chronic gastroduodenal ulcers.
Topics: Animals; Aspirin; Chronic Disease; Diet; Digestive System; Duodenum; Gastric Acid; Gastric Mucins; G | 1982 |
Pharmacokinetics of phenylbutazone in chronic liver disease.
Topics: Adult; Chronic Disease; Female; Humans; Kinetics; Liver Diseases; Male; Phenylbutazone | 1980 |
Control of chronic erythema nodosum with naproxen.
Topics: Adult; Aspirin; Chronic Disease; Erythema Nodosum; Female; Humans; Naproxen; Phenylbutazone | 1980 |
Effects of ketoprofen and phenylbutazone on chronic hoof pain and lameness in the horse.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Foot Diseases; | 1995 |
Descriptive epidemiological study of equine laminitis.
Topics: Acepromazine; Acute Disease; Administration, Topical; Age Factors; Animals; Anti-Inflammatory Agents | 1995 |
Fistulation of the auditory tube diverticulum (guttural pouch) with a neodymium:yttrium-aluminum-garnet laser for treatment of chronic empyema in two horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dexamethasone; Ear Diseases; Empy | 2001 |
[Clinical result of the treatment of chronic rheumatoid arthritis by non-steroidal anti-inflammatory agent, clofezone. Comparative study with phenylbutazone in a double-blid study at several clinics].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle A | 1976 |
Studies on the anti-inflammatory activity of creatine.
Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents; Chronic Disease; Creatine; Female; Inf | 1978 |
Alteration of Hepatic microsomal enzyme systems and the lethal action of non-steroidal anti-arthritic drugs in acute and chronic models of inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Carrageenan; Chr | 1977 |
Decreased drug binding in serum from patients with chronic hepatic disease.
Topics: Adult; Aged; Bilirubin; Blood Proteins; Chronic Disease; Female; Humans; Liver Diseases; Male; Middl | 1976 |
[Rheumopirin in the treatment of chronic adnexitis and parametritis].
Topics: Aminopyrine; Chronic Disease; Drug Combinations; Female; Humans; Parametritis; Pelvic Inflammatory D | 1976 |
[Effect of butadione on lipid metabolism in chronic ischemic heart disease patients].
Topics: Chronic Disease; Coronary Disease; Dipyridamole; Drug Evaluation; Drug Therapy, Combination; Humans; | 1986 |
Laboratory models of chronic granulomatous disease.
Topics: Amobarbital; Animals; Blood Bactericidal Activity; Chronic Disease; Dehydroepiandrosterone; Dihydrol | 1972 |
[Therapy of chronic polyarthritis in the practice].
Topics: Adrenocorticotropic Hormone; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Chronic Disease; Cyc | 1971 |
Management of chronic and recurrent gout.
Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy; | 1971 |
Treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chronic Disease; Gold; Hot Temperature; Humans; Hydrocortisone; Indomethacin; | 1974 |
[Incidence of thrombosis and the status of coagulation in ischaemic heart disease].
Topics: Acute Disease; Aspirin; Blood Coagulation; Chronic Disease; Coronary Disease; Depression, Chemical; | 1974 |
[Therapy of rheumatic processes with special reference to progressive chronic polyarthritis and related types of collagen diseases].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Collagen Diseases; Humans; Phenylb | 1972 |
[Modern therapy of gout].
Topics: Acute Disease; Chronic Disease; Colchicine; Diet, Reducing; Female; Gout; Humans; Indomethacin; Kidn | 1972 |
[Current etiopathogenetic and therapeutic views concerning gout and hyperuremic syndromes].
Topics: Acute Disease; Aged; Antimetabolites; Chronic Disease; Colchicine; Female; Genetic Code; Gout; Human | 1973 |
Renal enzyme excretion following administration of analgesic and antirheumatic drugs. Acute and chronic experiments.
Topics: Acute Disease; Alkaline Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Chronic Disease; | 1973 |
[Increasing the effectiveness of treating typhoid fever and other infectious diseases].
Topics: Acute Disease; Adolescent; Adult; Chloramphenicol; Chronic Disease; Communicable Diseases; Drug Ther | 1973 |
[Chondrocalcinosis ("pseudogout")].
Topics: Adrenal Cortex Hormones; Adult; Arthritis; Cartilage, Articular; Chondrocalcinosis; Chronic Disease; | 1974 |
[Experimental results of combinations of nonsteroid anti-inflammatory agents in acute and chronic inflammation].
Topics: Acute Disease; Animals; Arthritis; Carrageenan; Chronic Disease; Drug Therapy, Combination; Edema; F | 1974 |
[Principles in the treatment of chronic rheumatic diseases].
Topics: Adrenal Cortex Hormones; Chronic Disease; Humans; Indomethacin; Osteoarthritis; Phenylbutazone; Sali | 1974 |
[Use of indomethacin in combination with other antirheumatic drugs in the therapy of chronic inflammatory rheumatism].
Topics: Arthritis, Rheumatoid; Aspirin; Chronic Disease; Dexamethasone; Drug Synergism; Flufenamic Acid; Gol | 1972 |
Slowed lysosomal enzyme release and its normalization by drugs in adjuvant-induced polyarthritis.
Topics: Acid Phosphatase; Amino Acids; Animals; Arthritis; Aspirin; Chronic Disease; Disease Models, Animal; | 1971 |
[The steroid-saving effect of indomethacin].
Topics: Arthritis, Rheumatoid; Chronic Disease; Drug Combinations; Drug Synergism; Glucocorticoids; Humans; | 1971 |
[Therapy of chronic gout].
Topics: Allopurinol; Chronic Disease; Drug Combinations; Gout; Humans; Indomethacin; Oxyphenbutazone; Phenyl | 1971 |
Anemia in rheumatoid arthritis.
Topics: Anemia; Arthritis, Rheumatoid; Chronic Disease; Female; Gastrointestinal Hemorrhage; Glucocorticoids | 1968 |
[Hydroxy-phenylbutazone in the treatment of chronic inflammatory rheumatisms].
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Inflammation; Male; Middle Aged; Phenylbut | 1967 |
Phenylbutazone and leukaemia. Is there a relationship?
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Chronic Disease; Female; Humans; Leukemia; Male | 1969 |
[Pancytopenia associated with total situs inversus (Fanconi's syndrome in adults)].
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Chronic Disease; Fanconi Syndrome; Humans; Leukemia; | 1969 |
[Therapy of rheumatic arthritis of the hip joint].
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Chronic Disease; Female; Hip; Hip Joint; Huma | 1969 |
[Comparative study of changes in gastric secretory function after stimulation with histamine and a phenylbutazone preparation].
Topics: Adult; Chronic Disease; Duodenal Ulcer; Enteritis; Female; Gastric Juice; Gastritis; Histamine; Huma | 1970 |
[Kidney findings in polyarthritis under antirheumatic therapy].
Topics: Acute Disease; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Female; Glomerulone | 1970 |
Rheumatology and the gastrointestinal tract.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arthritis; Arthritis, Rheumatoid; Chi | 1968 |
A controlled study of flufenamic acid in ankylosing spondylitis. A final report and follow-up study.
Topics: Adult; Anti-Inflammatory Agents; Capsules; Chronic Disease; Female; Flufenamic Acid; Fluorine; Follo | 1968 |
Pyrazolidines in the treatment of gout.
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents; Chronic Disease; Gout; Humans; Oxyphenbutazone | 1968 |
Management of gout.
Topics: Acute Disease; Allopurinol; Chronic Disease; Colchicine; Gout; Humans; Indomethacin; Metabolic Disea | 1969 |
[Clinical aspects of chronic gout].
Topics: Adult; Aged; Allopurinol; Anemia; Arthritis; Bicarbonates; Blood Sedimentation; Chronic Disease; Fem | 1966 |
[Value of butazolidin in the treatment of chronic progressive polyarthritis and technics of administration].
Topics: Arthritis, Rheumatoid; Chronic Disease; Humans; Indomethacin; Phenylbutazone | 1966 |
[Hydroxyphenylbutazone in the treatment of chronic inflammatory rheumatism].
Topics: Adolescent; Adult; Aged; Animals; Arthritis, Rheumatoid; Child; Child, Preschool; Chronic Disease; F | 1966 |