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phenylbutazone and Cholestasis

phenylbutazone has been researched along with Cholestasis in 14 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."7.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."3.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199014 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DI MARCO, G1
MELINI, L1
Bury, RW1
Mashford, ML1
Glaun, BP1
Saaroni, G1
Wright, R1
Krtek, V2
Chlumský, J2
Ishak, KG1
Kirchner, JP1
Dhar, JK1
González Macías, J1
De Castro del Pozo, S1
Sun, DC1
Berthelot, P1
Fossati, C1
Schenker, S1
Olson, KN1
Dunn, D1
Breen, KJ1
Combes, B1
Bode, C1
Martini, GA1
Klinger, W1
Elger, J1
Franke, H1
Reinicke, C1
Traeger, A1
Volkmann, H1
Wahrenberg, I1
Ankermann, H1
Read, AE1

Reviews

4 reviews available for phenylbutazone and Cholestasis

ArticleYear
Drug-induced chronic hepatitis.
    Springer seminars in immunopathology, 1980, Volume: 3, Issue:3

    Topics: Allopurinol; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Female; Granuloma

1980
Mechanisms and prediction of drug-induced liver disease.
    Gut, 1973, Volume: 14, Issue:4

    Topics: Adenosine Triphosphate; Age Factors; Animals; Bilirubin; Biotransformation; Carbon Isotopes; Carbon

1973
[Liver damage due to drugs. I].
    La Clinica terapeutica, 1974, Jan-15, Volume: 68, Issue:1

    Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re

1974
[Toxic liver injury].
    Medizinische Klinik, 1970, Jan-02, Volume: 65, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia

1970

Other Studies

10 other studies available for phenylbutazone and Cholestasis

ArticleYear
[Clinico-bioptic evaluation of jaundice with marked cholestasis with sclerotic development presumably caused by phenylbutazone].
    Il Fegato, 1962, Volume: 8

    Topics: Cholestasis; Humans; Jaundice; Phenylbutazone

1962
Acute phenylbutazone poisoning in a child.
    The Medical journal of Australia, 1983, May-14, Volume: 1, Issue:10

    Topics: Acute Disease; Child, Preschool; Cholestasis; Female; Humans; Hyperglycemia; Phenylbutazone

1983
[Hepatic cholestasis following Benetazone (proceedings)].
    Ceskoslovenska gastroenterologie a vyziva, 1978, Volume: 32, Issue:8

    Topics: Cholestasis; Humans; Phenylbutazone; Pyrazoles

1978
[Hepatic cholestasis due to benetazone].
    Vnitrni lekarstvi, 1979, Volume: 25, Issue:2

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Hip Joint; Humans; Joint Diseases

1979
Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:7

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Cholestasis; Diazepam; Granuloma; Hu

1977
[Metabolism of phenylbutazone in the liver (author's transl)].
    Medizinische Klinik, 1976, Sep-03, Volume: 71, Issue:36

    Topics: Alcoholism; Cholestasis; Diabetes Mellitus; Enzyme Induction; Epilepsy; Ethanol; Half-Life; Hepatiti

1976
Iatrogenic gastrointestinal diseases in the aged.
    Geriatrics, 1972, Volume: 27, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Cathartics; Chemical and Drug Induced Li

1972
Intrahepatic cholestasis due to therapy of rheumatoid arthritis.
    Gastroenterology, 1973, Volume: 64, Issue:4

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferase

1973
[Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages].
    Acta biologica et medica Germanica, 1970, Volume: 24, Issue:4

    Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Ascorbic Acid; Cholestasis; Endoplasmic Reticul

1970
Drugs and liver disease.
    Bristol medico-chirurgical journal (1963), 1969, Volume: 84, Issue:312

    Topics: Biliary Tract Diseases; Bilirubin; Brain Diseases; Carbon Tetrachloride Poisoning; Chemical and Drug

1969