phenylbutazone has been researched along with Cholestasis in 14 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy." | 7.65 | Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977) |
| "A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy." | 3.65 | Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DI MARCO, G | 1 |
| MELINI, L | 1 |
| Bury, RW | 1 |
| Mashford, ML | 1 |
| Glaun, BP | 1 |
| Saaroni, G | 1 |
| Wright, R | 1 |
| Krtek, V | 2 |
| Chlumský, J | 2 |
| Ishak, KG | 1 |
| Kirchner, JP | 1 |
| Dhar, JK | 1 |
| González Macías, J | 1 |
| De Castro del Pozo, S | 1 |
| Sun, DC | 1 |
| Berthelot, P | 1 |
| Fossati, C | 1 |
| Schenker, S | 1 |
| Olson, KN | 1 |
| Dunn, D | 1 |
| Breen, KJ | 1 |
| Combes, B | 1 |
| Bode, C | 1 |
| Martini, GA | 1 |
| Klinger, W | 1 |
| Elger, J | 1 |
| Franke, H | 1 |
| Reinicke, C | 1 |
| Traeger, A | 1 |
| Volkmann, H | 1 |
| Wahrenberg, I | 1 |
| Ankermann, H | 1 |
| Read, AE | 1 |
4 reviews available for phenylbutazone and Cholestasis
| Article | Year |
|---|---|
Drug-induced chronic hepatitis.
Topics: Allopurinol; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Female; Granuloma | 1980 |
Mechanisms and prediction of drug-induced liver disease.
Topics: Adenosine Triphosphate; Age Factors; Animals; Bilirubin; Biotransformation; Carbon Isotopes; Carbon | 1973 |
[Liver damage due to drugs. I].
Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re | 1974 |
[Toxic liver injury].
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia | 1970 |
10 other studies available for phenylbutazone and Cholestasis
| Article | Year |
|---|---|
[Clinico-bioptic evaluation of jaundice with marked cholestasis with sclerotic development presumably caused by phenylbutazone].
Topics: Cholestasis; Humans; Jaundice; Phenylbutazone | 1962 |
Acute phenylbutazone poisoning in a child.
Topics: Acute Disease; Child, Preschool; Cholestasis; Female; Humans; Hyperglycemia; Phenylbutazone | 1983 |
[Hepatic cholestasis following Benetazone (proceedings)].
Topics: Cholestasis; Humans; Phenylbutazone; Pyrazoles | 1978 |
[Hepatic cholestasis due to benetazone].
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Hip Joint; Humans; Joint Diseases | 1979 |
Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases.
Topics: Aged; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Cholestasis; Diazepam; Granuloma; Hu | 1977 |
[Metabolism of phenylbutazone in the liver (author's transl)].
Topics: Alcoholism; Cholestasis; Diabetes Mellitus; Enzyme Induction; Epilepsy; Ethanol; Half-Life; Hepatiti | 1976 |
Iatrogenic gastrointestinal diseases in the aged.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Cathartics; Chemical and Drug Induced Li | 1972 |
Intrahepatic cholestasis due to therapy of rheumatoid arthritis.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferase | 1973 |
[Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages].
Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Ascorbic Acid; Cholestasis; Endoplasmic Reticul | 1970 |
Drugs and liver disease.
Topics: Biliary Tract Diseases; Bilirubin; Brain Diseases; Carbon Tetrachloride Poisoning; Chemical and Drug | 1969 |