phenylbutazone has been researched along with Asthma in 23 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-seven human volunteer asthmatic patients were each given one tablet of mofebutazone (300 mg) twice daily for 15 days." | 7.69 | Tolerability of mofebutazone in asthmatic patients. ( El-Ghazaly, M; El-Khatib, AS; Hatem, A; Khayyal, MT, 1995) |
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 7.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| "Twenty-seven human volunteer asthmatic patients were each given one tablet of mofebutazone (300 mg) twice daily for 15 days." | 3.69 | Tolerability of mofebutazone in asthmatic patients. ( El-Ghazaly, M; El-Khatib, AS; Hatem, A; Khayyal, MT, 1995) |
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 3.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (86.96) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ROWE, A | 1 |
| TUFFT, RW | 1 |
| MECHANICK, PG | 1 |
| ROWE, AH | 1 |
| LUCHERINI, T | 1 |
| CONESTABILE, E | 1 |
| NATALE, P | 1 |
| GOSPODINOFF, A | 1 |
| BARBERA, G | 1 |
| DELL'AERA, P | 1 |
| MUTH, HW | 1 |
| GIORDANO, M | 1 |
| ARA, M | 1 |
| TIRRI, G | 1 |
| SIMON, SW | 1 |
| ZICHA, L | 4 |
| SCHEIFFARTH, F | 2 |
| SCHEPP, F | 1 |
| BERGNER, D | 3 |
| METZLER, K | 1 |
| STRESEMANN, E | 2 |
| BIRATH, G | 1 |
| WESSEL-AAS, T | 1 |
| RASMUSSEN, KN | 1 |
| BONNEVIE, P | 1 |
| KORREKANGAS, AE | 1 |
| BJOERKMAN, S | 1 |
| LARSEN, K | 1 |
| SIMONSSON, B | 1 |
| KRATSCH, H | 2 |
| MILLER, P | 2 |
| Khayyal, MT | 2 |
| el-Khatib, AS | 2 |
| el-Ghazaly, M | 2 |
| Hatem, A | 2 |
| Hoigné, R | 1 |
| Leynadier, F | 1 |
| Perrault, M | 1 |
| Szczeklik, A | 2 |
| Gryglewski, RJ | 2 |
| Nizankowska, E | 1 |
| Kordansky, D | 1 |
| Adkinson, NF | 1 |
| Norman, PS | 1 |
| Rosenthal, RR | 1 |
| Czerniawska-Mysik, G | 1 |
| Williams, WR | 1 |
| Pawlowicz, A | 1 |
| Davies, BH | 1 |
| Schmid, E | 1 |
| Tauber, O | 1 |
| Finger, H | 1 |
| Bloom, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615] | 50 participants (Anticipated) | Interventional | 2012-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for phenylbutazone and Asthma
| Article | Year |
|---|---|
Asthma improved by nonsteroidal anti-inflammatory drugs.
Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forc | 1978 |
22 other studies available for phenylbutazone and Asthma
| Article | Year |
|---|---|
Phenylbutazone (butazolidin) in musculoskeletal diseases, bronchial asthma and other allergic diseases.
Topics: Analgesics; Asthma; Hypersensitivity; Immune System Diseases; Musculoskeletal Diseases; Phenylbutazo | 1953 |
[Phenylbutazone in therapy of rheumatic diseases and bronchial asthma].
Topics: Analgesics; Arthritis; Arthritis, Rheumatoid; Asthma; Electrocardiography; Humans; Phenylbutazone; R | 1953 |
[Phenylbutazone therapy of bronchial asthma].
Topics: Analgesics; Asthma; Humans; Phenylbutazone | 1954 |
[Treatment of bronchial asthma with phenylbutazone].
Topics: Asthma; Phenylbutazone | 1957 |
[Combination of prednisone & butazolidin].
Topics: Asthma; Disease; Lymphatic Diseases; Lymphatic System; Phenylbutazone; Prednisone; Rheumatic Disease | 1958 |
[Combined phenylbutazone and prednisone in therapy of rheumatic diseases and bronchial asthma].
Topics: Arthritis; Arthritis, Rheumatoid; Asthma; Humans; Phenylbutazone; Prednisone; Rheumatic Diseases; Rh | 1959 |
Evaluation of anti-inflammatory agents in the treatment of chronic infectious asthma.
Topics: Anti-Inflammatory Agents; Asthma; Chronic Disease; Communicable Diseases; Phenylbutazone; Prednisolo | 1962 |
[STUDIES ON THE ACETYLCHOLINE- ANTAGONISTIC EFFECTS OF GLUCOCORTICOID ESTERS].
Topics: Acetylcholine; Anti-Allergic Agents; Asthma; Cholinergic Antagonists; Dexamethasone; Esters; Glucoco | 1963 |
[THE EFFECT OF ANTIPYRETIC AND ANALGESIC SUBSTANCES ON HUMAN BRONCHIAL ASTHMA AND EXPERIMENTAL ASTHMA IN GUINEA PIGS].
Topics: Acetylcholine; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anaphylaxis; Animals; Antipyretics | 1963 |
[THE EFFECT OF BRADYKININ AEROSOL ON THE RESPIRATION OF HUMANS AND GUINEA PIGS AND THE INFLUENCE OF VARIOUS SUBSTANCE ON EXPERIMENTAL BRADYKININ BRONCHOSPASM].
Topics: Aerosols; Aminopyrine; Animals; Aspirin; Asthma; Atropine; Bradykinin; Bronchial Spasm; Guinea Pigs; | 1963 |
CHRONIC BRONCHITIS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Analgesics; Analgesics, Non-Narcotic; Anatomy; | 1964 |
[COMPARATIVE STUDIES ON ACETYLCHOLINE ANTAGONISM OF MONOPHENYLBUTAZONE, DIMETHYLAMINOETHANOL BITARTRATE, ISOPROPYLANTIPYRINE, CARISOPRODOL, TRASYLOL, RESPLANT AND PITRESSIN IN THE GUINEA PIG ASTHMA TEST. II].
Topics: Acetylcholine; Amino Alcohols; Antipyrine; Aprotinin; Arginine Vasopressin; Asthma; Carisoprodol; Ch | 1964 |
[COMPARATIVE STUDIES ON HISTAMINE AND SEROTONIN ANTAGONISM OF MONOPHENYLBUTAZONE, DIMETHYLAMINOETHANOL BITARTRATE, ISOPROPYLANTIPYRINE, CARISOPRODOL, TRASYLOL, RESPLANT AND PITRESSIN IN THE GUINEA PIG ASTHMA TEST. 1].
Topics: Amino Alcohols; Antipyrine; Aprotinin; Arginine Vasopressin; Asthma; Carisoprodol; Deanol; Enzyme In | 1964 |
Inhibition of leukotriene release by mofebutazone: a possible clinical advantage.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Guinea Pigs; Humans; In Vit | 1993 |
Tolerability of mofebutazone in asthmatic patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Forced Expiratory Volume; Humans; Ma | 1995 |
[Diagnostic problems in drug hypersensitivity].
Topics: Agranulocytosis; Ampicillin; Anaphylaxis; Anemia, Hemolytic; Aspirin; Asthma; Drug Eruptions; Drug H | 1977 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
Asthma and nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Humans; Phenylbutazone | 1979 |
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H | 1975 |
Aspirin-sensitive asthma: significance of the cyclooxygenase-inhibiting and protein-binding properties of analgesic drugs.
Topics: Acetaminophen; Administration, Inhalation; Adult; Aged; Aspirin; Asthma; Dinoprost; Drug Tolerance; | 1991 |
[Clinical and experimental studies on phenylbutazone and oxyphenbutazone].
Topics: Acetylcholine; Animals; Asthma; Gastric Juice; Guinea Pigs; Histamine H1 Antagonists; Humans; Oxyphe | 1965 |
Suppositories.
Topics: Aminophylline; Arthritis, Rheumatoid; Asthma; Colitis, Ulcerative; Constipation; Ergotamine; Hemorrh | 1971 |