phenylbutazone and Anemia, Macrocytic studies

phenylbutazone and Anemia, Macrocytic

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Anemia, Macrocytic: Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).

Research Excerpts

Excerpt	Relevance	Reference
"Two examples of hematological toxicity following phenylbutazone therapy are described, one of agranulocytosis and one of aplastic anemia."	3.64	HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES. ( CHALMERS, TM; MCCARTHY, DD, 1964)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

4 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
NIEWEG, HO	1
BOUMA, HG	1
SOEPARMAN, R	1
ABELS, J	1
MCCARTHY, DD	1
CHALMERS, TM	1
Hausmann, K	1
Skrandies, G	1
Sachtleben, P	1
Deller, DJ	1
Urban, E	1
Ibbotson, RN	1
Horwood, J	1
Milazzo, S	1
Robson, HN	1

Studies

NIEWEG, HO

BOUMA, HG

SOEPARMAN, R

ABELS, J

MCCARTHY, DD

CHALMERS, TM

Hausmann, K

Skrandies, G

Sachtleben, P

Deller, DJ

Urban, E

Ibbotson, RN

Horwood, J

Milazzo, S

Robson, HN

Other Studies

4 other studies available for phenylbutazone and Anemia, Macrocytic

Article	Year
[CLINICAL STUDY ON CHANGES IN THE BLOOD CAUSED BY DRUGS]. Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107 Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Blood Platelet Disorders; Chloramphenicol; Chloroquine;	1963
HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES. Canadian Medical Association journal, 1964, May-02, Volume: 90 Topics: Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Arthritis; Arthr	1964
[Current aspects of iatrogenic lesions of the bone marrow]. Minerva medica, 1976, Nov-14, Volume: 67, Issue:55 Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol;	1976
Folic-acid deficiency in rheumatoid arthritis: relation of levels of serum folic-acid activity to treatment with phenylbutazone. British medical journal, 1966, Mar-26, Volume: 1, Issue:5490 Topics: Anemia, Macrocytic; Arthritis, Rheumatoid; Blood; Female; Folic Acid; Folic Acid Deficiency; Humans;	1966

Article

Year

[CLINICAL STUDY ON CHANGES IN THE BLOOD CAUSED BY DRUGS].

Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107

Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Blood Platelet Disorders; Chloramphenicol; Chloroquine;

1963

HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES.

Canadian Medical Association journal, 1964, May-02, Volume: 90

Topics: Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Arthritis; Arthr

1964

[Current aspects of iatrogenic lesions of the bone marrow].

Minerva medica, 1976, Nov-14, Volume: 67, Issue:55

Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol;

1976

Folic-acid deficiency in rheumatoid arthritis: relation of levels of serum folic-acid activity to treatment with phenylbutazone.

British medical journal, 1966, Mar-26, Volume: 1, Issue:5490

Topics: Anemia, Macrocytic; Arthritis, Rheumatoid; Blood; Female; Folic Acid; Folic Acid Deficiency; Humans;

1966