phenylbutazone and Allergy, Drug studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Research Excerpts

Excerpt	Relevance	Reference
"Agranulocytosis and liver injury is described in a patient with Reiter's syndrome of 3 years duration who received pyrazinobutazone for 6 weeks before the development of the clinical picture reported."	7.67	Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism. ( da Silva, JA; Maria, VA; Victorino, RM, 1989)
"Two patients had phenylbutazone-induced systemic vasculitis syndrome."	7.67	Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. ( Dobbie, JW; Jones, JM; Leung, AC; McLay, A, 1985)
"Acute oliguric renal failure due to acute interstitial nephritis developed in a patient after treatment with phenylbutazone."	7.66	[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication]. ( Briner, J; Fontana, A; Kuhlmann, U; Siegenthaler, W; Steinemann, U, 1978)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."	7.65	Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
"Drug-induced sialadenitis is uncommon and unrecognized."	5.31	[Phenylbutazone-induced sialadenitis fever simulating angioedema]. ( Béguin, L; Carmi, E; Lafon, B; Lok, C; Mayeux, I; Poulain, JF; Sarraj, A; Viseux, V, 2002)
"Agranulocytosis and liver injury is described in a patient with Reiter's syndrome of 3 years duration who received pyrazinobutazone for 6 weeks before the development of the clinical picture reported."	3.67	Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism. ( da Silva, JA; Maria, VA; Victorino, RM, 1989)
"Two patients had phenylbutazone-induced systemic vasculitis syndrome."	3.67	Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. ( Dobbie, JW; Jones, JM; Leung, AC; McLay, A, 1985)
"Acute oliguric renal failure due to acute interstitial nephritis developed in a patient after treatment with phenylbutazone."	3.66	[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication]. ( Briner, J; Fontana, A; Kuhlmann, U; Siegenthaler, W; Steinemann, U, 1978)
"Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs."	3.65	Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975)
"Drug-induced sialadenitis is uncommon and unrecognized."	1.31	[Phenylbutazone-induced sialadenitis fever simulating angioedema]. ( Béguin, L; Carmi, E; Lafon, B; Lok, C; Mayeux, I; Poulain, JF; Sarraj, A; Viseux, V, 2002)

Timeframe	Studies, this research(%)	All Research%
pre-1990	68 (98.55)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (1.45)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
ANDERES, W	1
GOLDSTEIN, G	1
NIEWEG, HO	2
BOUMA, HG	2
DEVRIES, K	1
JANSZ, A	1
VACHTENHEIM, J	1
TERZANI, A	1
SOEPARMAN, R	1
ABELS, J	1
WIEK, K	1
WANKA, J	1
JONES, LI	1
WOOD, PH	1
DIXON, AS	1
OPPEL, O	1
BOEHM, C	1
HELLE, S	1
Kesseler, A	1
Aladenise, J	1
Boivin, MJ	1
Greninger, G	1
Selwyn, JG	1
Baudo, F	1
Cipriani, D	1
De Cataldo, F	1
Ladelli, G	1
Pensabene, A	1
Varga, M	1
Szurgent, J	1
Andreeva, GP	1
Krivoshchekova, VG	1
Viseux, V	1
Béguin, L	1
Poulain, JF	1
Sarraj, A	1
Mayeux, I	1
Carmi, E	1
Lafon, B	1
Lok, C	1
Heimpel, H	1
Kern, P	1
Bernasconi, C	1
Kaaber, K	1
Thormann, J	1
Hoigné, R	1
Kuhlmann, U	1
Fontana, A	1
Briner, J	1
Steinemann, U	1
Siegenthaler, W	1
Leynadier, F	1
Perrault, M	1
Russell, GI	1
Bing, RF	1
Walls, J	1
Pettigrew, NM	1
Zucker, G	1
Stiller, D	1
Tolot, F	1
Prost, G	1
Guignot, B	1
Pelletier, M	1
Thurston, JG	1
Marks, P	1
Trapnell, D	1
Magas, A	1
Szczeklik, A	1
Gryglewski, RJ	1
Czerniawska-Mysik, G	1
Kasper, MF	1
Schneider, CH	1
Rolli, H	1
Angst, BD	1
de Weck, AL	1
Maria, VA	1
da Silva, JA	1
Victorino, RM	1
Schlegel, SI	1
Paulus, HE	1
Leung, AC	1
McLay, A	1
Dobbie, JW	1
Jones, JM	1
Hadnagy, C	1
Macavei, I	1
Bornuz, F	1
Marinca, E	1
Sass, G	1
Littlejohns, DW	1
Assem, ES	1
Kennedy, CT	1
Michalski, H	1
Kinsella, TD	1
MacKenzie, KR	1
Kim, SO	1
Johnson, LG	1
Vesell, ES	1
Paschoud, JM	1
Raith, W	1
Königstein, RP	1
Maberly, DJ	1
Greenhalgh, RM	1
Louis, P	1
Coursin, DB	1
Bouletreau, P	1
Ducluzeau, R	1
Vasilenko, VKh	1
Tsodikov, GV	1
Minushkin, ON	1
Nenning, K	1
Schulz, KH	1
Mills, JA	1
Nagy, E	1
Tamási, P	1
Demény, P	1
Simon, N	1
Dobozy, A	1
Hunyadi, J	1
Voborová, A	1
Krtková, J	1
Nayyar, KC	1
Pasricha, JS	1
Hahn, KJ	1
Morgenstern, E	1
Weber, E	1
Banks, P	1
Hartl, W	1
Puxeddu, A	1
Dietrich, FM	1
Hess, R	1
Coltorti, M	1
Cuccurullo, L	1
Del Vecchio-Blanco, C	1
Zuffa, M	1
Tovarys, A	1
Brunová, E	1
Lang, KF	1
Brodersen, HC	1
Bose, E	1
Schuster, HP	1
Just, HG	1
Krasznai, G	1
Szegedi, G	1
Pevzner, GI	1
Tritsch, H	1
Rerrick, EG	1
Wajcner, G	1
Guedon, J	1
Chapman, A	1
Denman, EJ	1
Denman, AM	1
Beickert, A	1
Maiwald, D	1
Gold, SC	1
Wohlstein, E	1
Horváth, G	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615]				50 participants (Anticipated)	Interventional	2012-09-30	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
[Drug-induced panmyelopathies]. Blut, 1976, Volume: 33, Issue:1 Topics: Anemia, Aplastic; Antithyroid Agents; Carbutamide; Chloramphenicol; Diseases in Twins; Dose-Response	1976
[Multiple manifestations of intolerance in association with anti-inflammatory agents. Role of phenylbutazone]. Semaine des hopitaux. Therapeutique, 1976, Volume: 52, Issue:3 Topics: Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Tolera	1976
Non-steroidal and analgesic therapy in the elderly. Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1 Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen	1986
Recent progress in pharmacogenetics. Advances in pharmacology, 1969, Volume: 7 Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; C	1969
[Effect of some antirheumatic agents on the gastric mucous membrane]. Klinicheskaia meditsina, 1971, Volume: 49, Issue:8 Topics: Adrenocorticotropic Hormone; Aged; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheuma	1971
Nonsteroidal anti-inflammatory drugs (first of two parts). The New England journal of medicine, 1974, Apr-04, Volume: 290, Issue:14 Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Drug Hypersensitivity; Gastric	1974

Article	Year
[On a case of "toxic epidermal necrolysis" (Lyell) with severe eye complications]. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1963, Volume: 145 Topics: Drug Hypersensitivity; Humans; Keratoconjunctivitis; Phenylbutazone; Skin; Stevens-Johnson Syndrome	1963
SARCOID REACTIONS ASSOCIATED WITH PHENYLBUTAZONE HYPERSENSITIVITY. Annals of internal medicine, 1963, Volume: 59 Topics: Drug Hypersensitivity; Humans; Liver; Lymph Nodes; Phenylbutazone; Sarcoidosis; Spleen; Toxicology	1963
HAEMATOLOGICAL SIDE-EFFECTS OF SOME ANTI-RHEUMATIC DRUGS. Annals of the rheumatic diseases, 1963, Volume: 22 Topics: Aminopyrine; Antirheumatic Agents; Aspirin; Blood Platelets; Chloroquine; Colchicine; Complement Fix	1963
[PROVOCATING FACTORS IN SYSTEMIC LUPUS ERYTHEMATOSUS (WITH REFERENCE TO THERAPEUTIC AGENTS)]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1963, Sep-15, Volume: 18 Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Drug Hypersensitivity; Drug Therapy; Go	1963
[DAMAGE FROM THERAPY]. La Clinica terapeutica, 1963, Oct-15, Volume: 27 Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompati	1963
[CLINICAL STUDY ON CHANGES IN THE BLOOD CAUSED BY DRUGS]. Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107 Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Blood Platelet Disorders; Chloramphenicol; Chloroquine;	1963
[ON THE CLINICAL ASPECTS OF AGRANULOCYTOSIS]. Medizinische Klinik, 1964, Jan-10, Volume: 59 Topics: Agranulocytosis; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chlorpromazine; Dr	1964
INDOMETHACIN IN RHEUMATIC DISEASES. A CONTROLLED CLINICAL TRIAL. Annals of the rheumatic diseases, 1964, Volume: 23 Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Research; Drug Hypersensitivity; Gastrointesti	1964
[EYE INVOLVEMENT IN TOXICODERMA]. Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft, 1964, Volume: 65 Topics: Aminopyrine; Corneal Opacity; Corneal Ulcer; Drug Hypersensitivity; Exanthema; Phenylbutazone; Skin	1964
[ON HEMATOLOGIC SIDE-EFFECTS OF PHENYLBUTAZONE]. Medizinische Klinik, 1964, Aug-07, Volume: 59 Topics: Agranulocytosis; Drug Hypersensitivity; Phenylbutazone; Thrombocytopenia; Toxicology	1964
[LYELL'S TOXIC EPIDERMAL NECROLYSIS]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1964, Nov-15, Volume: 37 Topics: Drug Hypersensitivity; Humans; Phenacetin; Phenylbutazone; Stevens-Johnson Syndrome; Toxicology	1964
[Macroscopic hematuria during treatment with phenylbutazone derivatives. Positive lymphocyte transformation test for these drugs. Two cases in children]. Annales de pediatrie, 1977, Volume: 24, Issue:10 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diagnosis,	1977
Hypersensitivity reactions to phenylbutazone. British medical journal, 1967, Nov-25, Volume: 4, Issue:5577 Topics: Aged; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Infecti	1967
[Coagulation disorders with comsumption of coagulation factors, probably due to drug hypersensitivity]. Minerva medica, 1967, Dec-15, Volume: 58, Issue:100 Topics: Adult; Afibrinogenemia; Blood Coagulation Disorders; Drug Hypersensitivity; Female; Hemorrhagic Diso	1967
[Contact sensitization effect of phenylbutazone found in an 8-year patient material of the dermatologic department of the St. Stephen Hospital in Budapest]. Orvosi hetilap, 1980, Mar-16, Volume: 121, Issue:11 Topics: Dermatitis, Contact; Dermatology; Drug Hypersensitivity; Hospital Departments; Humans; Hungary; Intr	1980
[Lyell's syndrome as a consequence of reopirin sensitization]. Sovetskaia meditsina, 1980, Issue:8 Topics: Aminopyrine; Drug Combinations; Drug Hypersensitivity; Female; Humans; Middle Aged; Phenylbutazone;	1980
[Phenylbutazone-induced sialadenitis fever simulating angioedema]. Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:1 Pt 1 Topics: Angioedema; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Hypersensitivity; Female; Fever of	2002
[Granulocytopenias due to drugs (author's transl)]. Haematologica, 1979, Volume: 64 Suppl Topics: Agranulocytosis; Aminopyrine; Antithyroid Agents; Chloramphenicol; Drug Hypersensitivity; Humans; Ne	1979
[Contact allergy after phenylbutazone ointment. 4 cases and a review]. Ugeskrift for laeger, 1976, Jul-12, Volume: 138, Issue:29 Topics: Dermatitis, Atopic; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Midd	1976
[Diagnostic problems in drug hypersensitivity]. Anasthesiologische und intensivmedizinische Praxis, 1977, Volume: 14, Issue:1 Topics: Agranulocytosis; Ampicillin; Anaphylaxis; Anemia, Hemolytic; Aspirin; Asthma; Drug Eruptions; Drug H	1977
[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication]. Schweizerische medizinische Wochenschrift, 1978, Apr-01, Volume: 108, Issue:13 Topics: Acute Kidney Injury; Adult; Back Pain; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Dela	1978
[Anti-inflammatory agents in current therapeutics]. La Revue du praticien, 1975, Jan-21, Volume: 25, Issue:5 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi	1975
Interstitial nephritis in a case of phenylbutazone hypersensitivity. British medical journal, 1978, May-20, Volume: 1, Issue:6123 Topics: Drug Hypersensitivity; Female; Humans; Kidney Tubules; Middle Aged; Nephritis, Interstitial; Phenylb	1978
[Immunologic in vitro diagnosis of the Lyell syndrome]. Dermatologische Monatschrift, 1978, Volume: 164, Issue:7 Topics: Adult; Cell Migration Inhibition; Codeine; Cytoplasmic Granules; Drug Hypersensitivity; Humans; Lymp	1978
Lung changes associated with phenylbutazone treatment. British medical journal, 1976, Dec-11, Volume: 2, Issue:6049 Topics: Aged; Autoantibodies; Drug Hypersensitivity; Humans; Lung Diseases; Male; Phenylbutazone	1976
[Drug-induced allergic stomatitis based on 2 cases]. Czasopismo stomatologiczne, 1975, Volume: 28, Issue:7 Topics: Adult; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Phenylbutazone; Stomatitis	1975
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. British medical journal, 1975, Jan-11, Volume: 1, Issue:5949 Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H	1975
Diagnostic reagents in drug allergy: immunochemical specificity in the 1,2-diphenyl-pyrazolidinedione series. Immunobiology, 1986, Volume: 173, Issue:1 Topics: Animals; Cross Reactions; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Epitopes; Guinea	1986
Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism. The Journal of rheumatology, 1989, Volume: 16, Issue:11 Topics: Adult; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Drug Hypersens	1989
Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. Archives of internal medicine, 1985, Volume: 145, Issue:4 Topics: Acute Kidney Injury; Aged; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Glomerulonep	1985
[Bone marrow-damaging effect of various drugs]. Zeitschrift fur arztliche Fortbildung, 1985, Volume: 79, Issue:9 Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combinatio	1985
Immunological evidence of two forms of allergy to pyrazolone drugs. Rheumatology and rehabilitation, 1973, Volume: 12, Issue:2 Topics: Aged; Drug Eruptions; Drug Hypersensitivity; Female; Fever; Histamine Release; Humans; Immunoglobuli	1973
[Immunomorphological studies on lymphocytes in drug allergies]. Folia haematologica (Leipzig, Germany : 1928), 1974, Volume: 101, Issue:4 Topics: Aminopyrine; Cells, Cultured; Drug Hypersensitivity; Fluorescent Antibody Technique; gamma-Globulins	1974
[Vasculitis allergica cutis caused by phenylbutazone]. Dermatologica, 1966, Volume: 133, Issue:1 Topics: Aged; Aminopyrine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Oxyphen	1966
[Phenylbutazone-exanthema with thrombocytic and myeloid reaction]. Dermatologische Wochenschrift, 1967, May-20, Volume: 153, Issue:20 Topics: Bone Marrow; Drug Eruptions; Drug Hypersensitivity; Exanthema; Humans; Male; Middle Aged; Phenylbuta	1967
Jaundice and exfoliative dermatitis due to phenylbutazone. The British journal of dermatology, 1970, Volume: 82, Issue:6 Topics: Dermatitis, Exfoliative; Drug Hypersensitivity; Female; Humans; Jaundice; Middle Aged; Phenylbutazon	1970
[Etiologic diagnosis of fixed drug exanthemas]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, Apr-15, Volume: 47, Issue:8 Topics: Barbiturates; Drug Eruptions; Drug Hypersensitivity; Exanthema; Humans; Phenacetin; Phenolphthaleins	1972
Stevens-Johnson syndrome: nonspecific parasensitivity reaction? JAMA, 1966, Oct-10, Volume: 198, Issue:2 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Chlorpropamide; Diagnos	1966
[Fatal therapeutic complications]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jun-26, Volume: 45, Issue:30 Topics: Adult; Aged; Anesthesia, Local; Anti-Bacterial Agents; Anticoagulants; Blood Group Incompatibility;	1969
[Drug-induced diseases of the mouth and jaw region]. Deutsche Stomatologie, 1972, Volume: 22, Issue:11 Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Antineoplastic Agents; Candidiasis, Oral; Dentin; Drug Hy	1972
[Lymphocyte transformation test in drug hypersensitivity]. Archiv fur dermatologische Forschung, 1972, Volume: 244 Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation;	1972
[Purpura of the skin caused by Rheosolon]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1973, Mar-15, Volume: 48, Issue:6 Topics: Adult; Aged; Drug Hypersensitivity; Female; Humans; Joint Diseases; Long-Term Care; Phenylbutazone;	1973
[Histone methylation of lymphocytes and its diagnostic significance]. Archiv fur dermatologische Forschung, 1972, Volume: 244 Topics: Aminopyrine; Cells, Cultured; Chloramphenicol; Cytotoxicity Tests, Immunologic; Drug Hypersensitivit	1972
[2 cases of Lyell's syndrome with a severe course]. Ceskoslovenska dermatologie, 1973, Volume: 48, Issue:6 Topics: Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Middle Aged; Phenylbutazone; Stevens-J	1973
Fixed drug eruption to oxyphenbutazone and phenylbutazone. Dermatologica, 1972, Volume: 144, Issue:4 Topics: Adult; Drug Hypersensitivity; Erythema; Female; Humans; Oxyphenbutazone; Phenylbutazone; Pruritus; S	1972
[Electron microscopy studies on the gastrointestinal intolerance of various drugs]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1971, Volume: 77 Topics: Aspirin; Chloramphenicol; Drug Hypersensitivity; Epithelial Cells; Gastrointestinal Diseases; Humans	1971
Hypersensitivity and drug reactions involving the parotid gland. The British journal of oral surgery, 1967, Volume: 5, Issue:1 Topics: Adult; Drug Hypersensitivity; Edema; Female; Glossitis; Humans; Hypersensitivity; Male; Middle Aged;	1967
[On the problem of specificity of drug-allergic immune reactions by aminophenazone-containing antirheumatic aents]. Klinische Wochenschrift, 1966, Jan-01, Volume: 44, Issue:1 Topics: Aminopyrine; Animals; Antigen-Antibody Reactions; Antipyrine; Complement Fixation Tests; Drug Hypers	1966
Hypersensitivity in mice. I. Induction of contact sensitivity to oxazolone and inhibition by various chemical compounds. International archives of allergy and applied immunology, 1970, Volume: 38, Issue:3 Topics: Animals; Antigens; Aspirin; Cortisone; Corynebacterium; Cyclophosphamide; Dermatitis, Contact; Dexam	1970
[Clinical and morphological findings on 2 cases of icterus induced by butazolidines]. Il Policlinico. Sezione pratica, 1970, Volume: 77, Issue:10 Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Liver; Male; M	1970
[Lethal allergic and toxic reaction following common drug administration]. Vnitrni lekarstvi, 1970, Volume: 16, Issue:9 Topics: Death, Sudden; Diabetes Mellitus; Drug Hypersensitivity; Female; Guaiacol; Guaifenesin; Humans; Keto	1970
[Allergo-toxic disturbances of the heart muscle with congestive heart failure as a result of parenteral treatment with phenylbutazone]. Vnitrni lekarstvi, 1971, Volume: 17, Issue:2 Topics: Drug Hypersensitivity; Heart; Heart Failure; Humans; Injections, Intravenous; Male; Middle Aged; Phe	1971
[Life threatening pleuropulmonary reaction as a drug side effect]. Die Medizinische Welt, 1971, Mar-27, Volume: 13 Topics: Analgesics; Drug Hypersensitivity; Female; Humans; Lung Diseases; Middle Aged; Phenylbutazone; Pyraz	1971
[Tumor-like phenylbutazone lymphadenopathy]. Frankfurter Zeitschrift fur Pathologie, 1967, Volume: 77, Issue:4 Topics: Adult; Cell Nucleus; Diagnosis, Differential; Drug Hypersensitivity; Female; Hodgkin Disease; Humans	1967
[Exudation into the pleural cavity in the use of butadion]. Klinicheskaia meditsina, 1967, Volume: 45, Issue:5 Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Phenylbutazone; Pleural Effusion	1967
[Histological picture report No. 203. Lyell syndrome]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1968, Apr-15, Volume: 43, Issue:8 Topics: Antipyrine; Child, Preschool; Drug Hypersensitivity; Female; Humans; Infant; Penicillins; Phenolphth	1968
Systemic allergic reaction due to phenylbutazone. The Journal of the Maine Medical Association, 1968, Volume: 59, Issue:9 Topics: Adult; Drug Hypersensitivity; Humans; Male; Phenylbutazone	1968
[Acute anuric renal insufficiency with necrosing arteriolitis. Etiologic problems]. Journal d'urologie et de nephrologie, 1968, Volume: 74, Issue:9 Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Angioedema; Anuria; Arteritis; Arthritis; Aspirin; Dr	1968
The lymphocyte transformation test and gold hypersensitivity. Annals of the rheumatic diseases, 1968, Volume: 27, Issue:6 Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Autoradiography; Drug Hypersensitivity; Female; Gold	1968
[A fatal pathological condition with hyperglobulinemic purpura and polymyositis after phenylbutazone]. Munchener medizinische Wochenschrift (1950), 1968, Nov-15, Volume: 110, Issue:46 Topics: Aged; Drug Hypersensitivity; Humans; Male; Myositis; Phenylbutazone; Purpura, Hyperglobulinemic	1968
Drug eruption. The British journal of dermatology, 1966, Volume: 78, Issue:10 Topics: Adult; Drug Hypersensitivity; Erythema; Female; Humans; Phenylbutazone	1966
[Usability of the electrodermatometric technic (Wohlstein) in pyrazolone derivative therapy]. Zeitschrift fur Rheumaforschung, 1966, Volume: 25, Issue:5 Topics: Antimalarials; Balneology; Colchicine; Collagen Diseases; Drug Hypersensitivity; Galvanic Skin Respo	1966

phenylbutazone and Allergy, Drug

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