Page last updated: 2024-11-02

phenylbutazone and Agranulocytosis

phenylbutazone has been researched along with Agranulocytosis in 81 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"Agranulocytosis and liver injury is described in a patient with Reiter's syndrome of 3 years duration who received pyrazinobutazone for 6 weeks before the development of the clinical picture reported."7.67Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism. ( da Silva, JA; Maria, VA; Victorino, RM, 1989)
"A previously healthy woman developed severe, periodic neutropenia after ingestion of phenylbutazone."7.66Acquired cyclic neutropenia: successful treatment with prednisone. ( Rodgers, GM; Shuman, MA, 1982)
" The herbal medicines were shown to contain substantial amounts of undeclared aminopyrine and phenylbutazone, drugs that are well-known causes of agranulocytosis."7.65Agranulocytosis caused by Chinese herbal medicines. Dangers of medications containing aminopyrine and phenylbutazone. ( Ries, CA; Sahud, MA, 1975)
"Agranulocytosis and liver injury is described in a patient with Reiter's syndrome of 3 years duration who received pyrazinobutazone for 6 weeks before the development of the clinical picture reported."3.67Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism. ( da Silva, JA; Maria, VA; Victorino, RM, 1989)
"A previously healthy woman developed severe, periodic neutropenia after ingestion of phenylbutazone."3.66Acquired cyclic neutropenia: successful treatment with prednisone. ( Rodgers, GM; Shuman, MA, 1982)
" The herbal medicines were shown to contain substantial amounts of undeclared aminopyrine and phenylbutazone, drugs that are well-known causes of agranulocytosis."3.65Agranulocytosis caused by Chinese herbal medicines. Dangers of medications containing aminopyrine and phenylbutazone. ( Ries, CA; Sahud, MA, 1975)
"Two examples of hematological toxicity following phenylbutazone therapy are described, one of agranulocytosis and one of aplastic anemia."3.64HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES. ( CHALMERS, TM; MCCARTHY, DD, 1964)
"Phenylbutazone (Butazolidin(R)), one of the newer antirheumatic drugs, while providing varying degrees of symptomatic relief in various types of rheumatism, may also cause serious toxic side effects."3.63Phenylbutazone: an evaluation of its use. ( SNOW, WG, 1953)
"The report of a recent fatality due to agranulocytosis provoked an examination of the plausible mechanisms of neutropenia and agranulocytosis."1.27A new concept in the relationship between biochemical reaction mechanisms and molecular basis of agranulocytosis. ( Akintonwa, DA, 1984)
"The risks of agranulocytosis and aplastic anemia in relation to analgesic drug use were evaluated in a population-based case-control study conducted in Europe and Israel."1.27Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study. ( , 1986)
" An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary."1.26[Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980)
"Thirteen out of 17 deaths from agranulocytosis were attributed to co-trimoxazole treatment."1.26Study of fatal bone marrow depression with special reference to phenylbutazone and oxyphenbutazone. ( Inman, WH, 1977)
"Aminopyrine alone was responsible for eight cases."1.24Agranulocytosis: a report of 30 cases. ( Colpron, G; Gosselin, G; Long, LA; Pretty, HM, 1965)

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199080 (98.77)18.7374
1990's0 (0.00)18.2507
2000's1 (1.23)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HINZ, C1
LAMONT-HAVERS, RW1
COMINSKY, B1
GAINES, LM1
STIFEL, JL1
BURNHEIMER, JC1
BERSHOF, E1
OXMAN, AC1
ETESS, AD1
JACOBSON, AS1
BENSTEAD, JG1
WERBLOW, SC1
NEBER, J1
STEINBERG, CL1
BOHROD, MG1
ROODENBURG, AI1
DILLING, NV1
KIELY, JM1
STICKNEY, JM1
BRANDWEIN, S1
VON RECHENBERG, HK1
SNOW, WG1
SALLSTRAND, M1
BEUTLER, E1
BERGENSTAL, DM1
ARCHER, BH1
KANTOR, MG1
O'BRIEN, DJ1
STOREY, G1
STEEL, SJ1
MOFFATT, JL1
WOOD, IH1
GSELL, OR1
STEIN, T1
BOTTIGER, LE1
LILJESTRAND, A1
KRUG, K1
GEESAMAN, RE2
JAMES, FL2
ARSLAN, A1
KJELDSEN, MH1
ZUCCONI, V1
BALESTRA, F1
SCHEUER-KARPIN, R1
JOPPICH, H1
BRETTSCHNEIDER, W1
TARANENKO, AF1
LENG-LEVY, J1
DAVID-CHAUSSE, J1
DU PASQUIER, R1
SERRES, A1
VEAUX, R1
BALDENBERGER, R1
HALBERG, P1
HUBER, J1
HAUGEN, J1
SKARSTEN, KW1
KENNEDY, RD1
HYNES, J1
BENNETT, NM1
MEYLER, L1
WIEK, K1
WALCZAK, H1
MCCARTHY, DD1
CHALMERS, TM1
THORPE, GJ1
BOEHM, C1
OLMER, J1
ABIGNOLI, E1
PERDRIX, L1
LOUYOT, P1
COLLIN, B1
PETIT, J1
Paul, J1
Duncan, JR1
Sharp, P1
Norris, A1
Siddiq, MA1
Bacon, C1
Weighill, J1
Akintonwa, DA1
Offerhaus, L1
Rodgers, GM1
Shuman, MA1
Knipping, W1
Dahinden, C1
Fehr, J1
Stobbe, H1
Hüge, W1
Naess, K1
Bernasconi, C1
Ries, CA1
Sahud, MA1
Hoigné, R1
Jeffcott, LB1
Colles, CM1
Schmitt, E1
Smith, CS1
Chinn, S3
Watts, RW6
Inman, WH1
Billekop, K1
Mosbech, J1
Rosenthal, M1
Maria, VA1
da Silva, JA1
Victorino, RM1
Chaplin, S1
Rachmilewitz, M1
Gracheva, NM1
Nenning, K1
Westwick, WJ1
Allsop, J1
Müller, WH1
Tanner, E1
Howell, A2
Andrews, TM3
Blackburn, MJ1
Prico, DF1
DeGregori, GJ1
McCurrach, PH1
Park, JK1
Perry, WL1
Pretty, HM1
Gosselin, G1
Colpron, G1
Long, LA1
Alcoba Leza, M1

Reviews

4 reviews available for phenylbutazone and Agranulocytosis

ArticleYear
Phenylbutazone and the horse--a review.
    Equine veterinary journal, 1977, Volume: 9, Issue:3

    Topics: Agranulocytosis; Anemia; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Horse Diseases; Horses; Hu

1977
[Treatment of ankylosing spondylitis].
    Medizinische Klinik, 1979, Sep-07, Volume: 74, Issue:36

    Topics: Agranulocytosis; Anti-Inflammatory Agents; Balneology; Edema; Exercise Therapy; Humans; Indomethacin

1979
Bone marrow depression due to mianserin, phenylbutazone, oxyphenbutazone, and chloramphenicol--Part I.
    Adverse drug reactions and acute poisoning reviews, 1986,Summer, Volume: 5, Issue:2

    Topics: Agranulocytosis; Anemia, Aplastic; Bone Marrow; Cell Membrane; Chloramphenicol; Dibenzazepines; DNA

1986
Disorders of the blood in changing environmental conditions.
    Hamatologie und Bluttransfusion, 1970, Volume: 9

    Topics: Agranulocytosis; Aminopyrine; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Antibody F

1970

Other Studies

77 other studies available for phenylbutazone and Agranulocytosis

ArticleYear
Agranulocytosis following use of phenylbutazone (butazolidin); report of a case.
    Journal of the American Medical Association, 1953, Jan-03, Volume: 151, Issue:1

    Topics: Agranulocytosis; Analgesics; Phenylbutazone

1953
RISKS of butazolidin therapy.
    British medical journal, 1953, Jan-31, Volume: 1, Issue:4804

    Topics: Agranulocytosis; Analgesics; Phenylbutazone; Risk

1953
Agranulocytosis following administration of phenylbutazone (butazolidin).
    Journal of the American Medical Association, 1953, Feb-14, Volume: 151, Issue:7

    Topics: Adrenocorticotropic Hormone; Agranulocytosis; Analgesics; Phenylbutazone

1953
Agranulocytosis following use of phenylbutazone (butazolidin).
    Journal of the American Medical Association, 1953, Feb-14, Volume: 151, Issue:7

    Topics: Adrenocorticotropic Hormone; Agranulocytosis; Analgesics; Phenylbutazone

1953
Fatality due to agranulocytosis following use of phenylbutazone (butazolidin).
    Journal of the American Medical Association, 1953, Feb-21, Volume: 151, Issue:8

    Topics: Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Phenylbutazone

1953
Deaths of two patients treated by phenylbutazone.
    British medical journal, 1953, Mar-28, Volume: 1, Issue:4812

    Topics: Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Peptic Ulcer; Phenylbutazone

1953
Agranulocytosis following phenylbutazone therapy.
    Journal of the American Medical Association, 1953, Apr-11, Volume: 151, Issue:15

    Topics: Adrenocorticotropic Hormone; Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Phenylbu

1953
Agranulocytosis following phenylbutazone (butazolidin) therapy; report of a fatal case.
    Journal of the American Medical Association, 1953, May-02, Volume: 152, Issue:1

    Topics: Agranulocytosis; Analgesics; Phenylbutazone

1953
Fatal agranulocytosis and gastric ulceration due to phenylbutazone.
    Lancet (London, England), 1953, Jun-20, Volume: 1, Issue:6773

    Topics: Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Phenylbutazone; Stomach

1953
Agranulocytosis caused by phenylbutazone and 4-amino-antipyrine.
    Proceedings of the staff meetings. Mayo Clinic, 1953, Jun-17, Volume: 28, Issue:12

    Topics: Agranulocytosis; Analgesics; Antipyrine; Phenylbutazone

1953
Agranulocytosis following phenylbutazone (Butazolidin).
    New York state journal of medicine, 1953, Jul-01, Volume: 53, Issue:13

    Topics: Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Phenylbutazone

1953
[Studies on butazolidine and irgapyrin in their relation to agranulocytosis].
    Acta haematologica, 1953, Volume: 9, Issue:6

    Topics: Agranulocytosis; Aminopyrine; Analgesics; Drug Combinations; Humans; Phenylbutazone

1953
Phenylbutazone: an evaluation of its use.
    California medicine, 1953, Volume: 79, Issue:3

    Topics: Agranulocytosis; Analgesics; Antirheumatic Agents; Arthritis, Rheumatoid; Gout; Osteoarthritis; Phen

1953
[Agranulocytosis after irgapyrin therapy].
    Svenska lakartidningen, 1953, Jun-19, Volume: 50, Issue:25

    Topics: Agranulocytosis; Aminopyrine; Analgesics; Drug Combinations; Phenylbutazone

1953
Perforated duodenal ulcer with neutropenia and death in a patient receiving phenylbutazone therapy.
    Gastroenterology, 1953, Volume: 25, Issue:1

    Topics: Agranulocytosis; Analgesics; Duodenal Ulcer; Humans; Neutropenia; Peptic Ulcer Perforation; Phenylbu

1953
Agranulocytosis with recovery following the use of phenylbutazone (Butazolidin).
    New York state journal of medicine, 1954, Volume: 54, Issue:3

    Topics: Agranulocytosis; Analgesics; Biological Phenomena; Phenylbutazone; Physiological Phenomena

1954
Death from hypersensitivity due to phenylbutazone.
    British medical journal, 1954, Apr-03, Volume: 1, Issue:4865

    Topics: Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Humans; Hypersensitivity; Phenylbutaz

1954
Stevens-Johnson syndrome and granulocytopenia after phenylbutazone.
    British medical journal, 1954, Apr-03, Volume: 1, Issue:4865

    Topics: Agranulocytosis; Analgesics; Erythema Multiforme; Humans; Penicillins; Phenylbutazone; Stevens-Johns

1954
Fatal case of agranulocytosis following phenylbutazone.
    British medical journal, 1954, Apr-03, Volume: 1, Issue:4865

    Topics: Agranulocytosis; Analgesics; Humans; Phenylbutazone

1954
Agranulocytosis associated with phenylbutazone therapy.
    International record of medicine and general practice clinics, 1954, Volume: 167, Issue:9

    Topics: Agranulocytosis; Analgesics; Humans; Phenylbutazone

1954
Fatal agranulocytosis following phenylbutazone (butazolidin) therapy; report of case with autopsy findings.
    Journal of the Medical Association of the State of Alabama, 1954, Volume: 24, Issue:4

    Topics: Agranulocytosis; Analgesics; Autopsy; Phenylbutazone

1954
[Agranulocytosis after phenylbutazone therapy].
    Svenska lakartidningen, 1954, Oct-08, Volume: 51, Issue:41

    Topics: Agranulocytosis; Analgesics; Phenylbutazone

1954
[Agranulocytosis after irgapyrin].
    Therapie der Gegenwart, 1954, Volume: 93, Issue:8

    Topics: Agranulocytosis; Aminopyrine; Analgesics; Drug Combinations; Phenylbutazone

1954
Agranulocytosis due to phenylbutazone.
    Annals of internal medicine, 1957, Volume: 46, Issue:1

    Topics: Agranulocytosis; Humans; Phenylbutazone

1957
Agranulocytosis due to phenylbutazone.
    Annals of internal medicine, 1957, Volume: 46, Issue:1

    Topics: Agranulocytosis; Humans; Phenylbutazone

1957
Agranulocytosis due to phenylbutazone.
    Annals of internal medicine, 1957, Volume: 46, Issue:1

    Topics: Agranulocytosis; Humans; Phenylbutazone

1957
Agranulocytosis due to phenylbutazone.
    Annals of internal medicine, 1957, Volume: 46, Issue:1

    Topics: Agranulocytosis; Humans; Phenylbutazone

1957
[Irgapyrin therapy and agranulocytosis].
    Turk Tip Cemiyeti mecmuasi, 1957, Volume: 23, Issue:4

    Topics: Agranulocytosis; Aminopyrine; Drug Combinations; Humans; Phenylbutazone

1957
[Agranulocytosis from phenylbutazone with the presence of autoantibodies in the blood].
    Lyon medical, 1957, Dec-01, Volume: 89, Issue:48

    Topics: Agranulocytosis; Autoantibodies; Health Services; Humans; Phenylbutazone

1957
[Agranulocytosis following phenylbutazone therapy].
    Ugeskrift for laeger, 1958, Jul-10, Volume: 120, Issue:28

    Topics: Agranulocytosis; Humans; Phenylbutazone

1958
[Two cases of agranulocytosis due to phenylbutazone].
    Rassegna giuliana di medicina, 1958, Volume: 14, Issue:10

    Topics: Agranulocytosis; Humans; Phenylbutazone

1958
[Severe allergic damage with fatal outcome caused by phenylbutazone].
    Zeitschrift fur arztliche Fortbildung, 1958, Dec-15, Volume: 52, Issue:24

    Topics: Agranulocytosis; Aminopyrine; Fatal Outcome; Humans; Phenylbutazone

1958
[Case of agranulocytosis following butadione therapy of rheumatic heart disease].
    Problemy gematologii i perelivaniia krovi, 1959, Volume: 4, Issue:5

    Topics: Agranulocytosis; Humans; Phenylbutazone; Rheumatic Heart Disease

1959
[Therapeutic complication caused by phenylbutazone (arterial thrombosis, gangrene, agranulocytosis, plasmocytosis)].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1959, Volume: 136, Issue:5

    Topics: Agranulocytosis; Gangrene; Humans; Leukocyte Disorders; Leukocytes; Phenylbutazone; Thrombosis

1959
[Agranulocytosis following phenylbutazone (butazolidine) treatment].
    Ugeskrift for laeger, 1959, Apr-23, Volume: 121, Issue:17

    Topics: Agranulocytosis; Humans; Phenylbutazone

1959
[Irgapyrin agraulocytosis].
    Schweizerische medizinische Wochenschrift, 1961, Aug-05, Volume: 91

    Topics: Agranulocytosis; Aminopyrine; Drug Combinations; Phenylbutazone

1961
[Granulocytopenia following oxyphenbutazone treatment].
    Nordisk medicin, 1962, Aug-16, Volume: 68

    Topics: Agranulocytosis; Humans; Oxyphenbutazone; Phenylbutazone

1962
Agranulocytosis due to oxyphen-butazone.
    Lancet (London, England), 1962, Nov-24, Volume: 2, Issue:7265

    Topics: Agranulocytosis; Humans; Phenylbutazone

1962
DRUG-INDUCED AGRANULOCYTOSIS AND SEPTICAEMIA.
    The Medical journal of Australia, 1963, Oct-05, Volume: 2

    Topics: Agranulocytosis; Antipsychotic Agents; Benzene; Chlorpromazine; Methylthiouracil; Phenothiazines; Ph

1963
[CHANGES IN THE BLOOD CAUSED BY DRUGS].
    Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107

    Topics: Agranulocytosis; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Chloramphenicol; Chlorpromazine; Drug

1963
[ON THE CLINICAL ASPECTS OF AGRANULOCYTOSIS].
    Medizinische Klinik, 1964, Jan-10, Volume: 59

    Topics: Agranulocytosis; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chlorpromazine; Dr

1964
[ON THE TREATMENT OF DIFFERENT TYPES OF RHEUMATIC DISEASES IN PULMONARY TUBERCULOSIS AND LUNG TUMORS].
    Zeitschrift fur Tuberkulose und Erkrankungen der Thoraxorgane, 1964, Volume: 121

    Topics: Agranulocytosis; Aminosalicylic Acid; Aminosalicylic Acids; Isoniazid; Leukopenia; Lung; Lung Neopla

1964
HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES.
    Canadian Medical Association journal, 1964, May-02, Volume: 90

    Topics: Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Arthritis; Arthr

1964
LEUKAEMIA AND PHENYLBUTAZONE.
    British medical journal, 1964, Jun-27, Volume: 1, Issue:5399

    Topics: Agranulocytosis; Anemia; Anemia, Aplastic; Leukemia; Leukemoid Reaction; Phenylbutazone; Subarachnoi

1964
[ON HEMATOLOGIC SIDE-EFFECTS OF PHENYLBUTAZONE].
    Medizinische Klinik, 1964, Aug-07, Volume: 59

    Topics: Agranulocytosis; Drug Hypersensitivity; Phenylbutazone; Thrombocytopenia; Toxicology

1964
[Acute fatal agranulocytosis caused by a weak dose of irgapyrin].
    Marseille medical, 1955, Volume: 92, Issue:2

    Topics: Agranulocytosis; Aminopyrine; Analgesics; Drug Combinations; Humans; Phenylbutazone

1955
[Agranulocytosis after moderate administration of phenylbutazone].
    La Revue du praticien, 1955, Apr-11, Volume: 5, Issue:11

    Topics: Agranulocytosis; Analgesics; Arthritis; Arthritis, Rheumatoid; Phenylbutazone

1955
Agranulocytosis and citrobacter infection associated with jamu, a herbal remedy containing phenylbutazone.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jun-15, Volume: 40, Issue:12

    Topics: Aged; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Citrobacter koseri; Drug Contaminati

2005
A new concept in the relationship between biochemical reaction mechanisms and molecular basis of agranulocytosis.
    Biochemical medicine, 1984, Volume: 32, Issue:2

    Topics: Agranulocytosis; Aminopyrine; Autoantibodies; Biotransformation; Blood Proteins; Chloramphenicol; Ch

1984
Phenylbutazone, oxyphenbutazone labeling revised.
    FDA drug bulletin, 1984, Volume: 14, Issue:3

    Topics: Agranulocytosis; Anemia, Aplastic; Drug Labeling; Humans; Oxyphenbutazone; Phenylbutazone

1984
[Russian roulette with pyrazolones].
    Nederlands tijdschrift voor geneeskunde, 1983, Apr-09, Volume: 127, Issue:15

    Topics: Agranulocytosis; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Female; Humans; Mal

1983
Acquired cyclic neutropenia: successful treatment with prednisone.
    American journal of hematology, 1982, Volume: 13, Issue:1

    Topics: Adult; Agranulocytosis; Colony-Forming Units Assay; Erythropoiesis; Female; Hematopoiesis; Humans; N

1982
[Problems of evaluating rare adverse drug reactions using as an example agranulocytosis induced by anti-arrhythmia agents].
    Medizinische Klinik, 1980, Feb-01, Volume: 75, Issue:3

    Topics: Aged; Agranulocytosis; Ajmaline; Anti-Arrhythmia Agents; Drug Therapy, Combination; Drug-Related Sid

1980
Receptor-directed inhibition of chemotactic factor-induced neutrophil hyperactivity by pyrazolon derivatives. Definition of a chemotactic peptide antagonist.
    The Journal of clinical investigation, 1980, Volume: 66, Issue:5

    Topics: Agranulocytosis; Arachidonic Acids; Aspirin; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocy

1980
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Dec-01, Volume: 35, Issue:23

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female;

1980
[Leukopenia and agranulocytosis induced by drugs].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-30, Volume: 96, Issue:9-10

    Topics: Agranulocytosis; Antithyroid Agents; Chlorpromazine; Humans; Leukopenia; Phenylbutazone; Thiourea

1976
[Granulocytopenias due to drugs (author's transl)].
    Haematologica, 1979, Volume: 64 Suppl

    Topics: Agranulocytosis; Aminopyrine; Antithyroid Agents; Chloramphenicol; Drug Hypersensitivity; Humans; Ne

1979
Agranulocytosis caused by Chinese herbal medicines. Dangers of medications containing aminopyrine and phenylbutazone.
    JAMA, 1975, Jan-27, Volume: 231, Issue:4

    Topics: Aged; Agranulocytosis; Aminopyrine; Arthritis; Back Pain; Bacteroides; Drug Synergism; Escherichia c

1975
[Diagnostic problems in drug hypersensitivity].
    Anasthesiologische und intensivmedizinische Praxis, 1977, Volume: 14, Issue:1

    Topics: Agranulocytosis; Ampicillin; Anaphylaxis; Anemia, Hemolytic; Aspirin; Asthma; Drug Eruptions; Drug H

1977
The sensitivity of human bone marrow granulocyte/monocyte precursor cells to phenylbutazone, oxyphenbutazone and gamma-hydroxyphenylbutazone in vitro, with observations on the bone marrow colony formation in phenylbutazone-induced granulocytopoenia.
    Biochemical pharmacology, 1977, May-01, Volume: 26, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Depression, Chem

1977
Study of fatal bone marrow depression with special reference to phenylbutazone and oxyphenbutazone.
    British medical journal, 1977, Jun-11, Volume: 1, Issue:6075

    Topics: Adolescent; Adult; Age Factors; Aged; Agranulocytosis; Anemia, Aplastic; Child; Death Certificates;

1977
Quantal responses lead to sigmoid curves [proceedings].
    The Journal of physiology, 1977, Volume: 267, Issue:1

    Topics: Adolescent; Agranulocytosis; Female; Humans; Menarche; Neutropenia; Phenylbutazone; Statistics as To

1977
[Mortality from agranulocytosis in Denmark during the period 1958-1972].
    Ugeskrift for laeger, 1976, Jul-05, Volume: 138, Issue:28

    Topics: Adolescent; Adult; Age Factors; Aged; Agranulocytosis; Child; Denmark; Female; Humans; Male; Middle

1976
Chinese herbal medicines.
    Clinical toxicology, 1975, Volume: 8, Issue:1

    Topics: Agranulocytosis; Aminopyrine; China; Humans; Magnoliopsida; Phenylbutazone; Phytotherapy; United Sta

1975
Letter: Use of aminopyrine in breath tests.
    Gastroenterology, 1975, Volume: 69, Issue:2

    Topics: Agranulocytosis; Aminopyrine; Breath Tests; Humans; Liver Function Tests; Phenylbutazone

1975
Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism.
    The Journal of rheumatology, 1989, Volume: 16, Issue:11

    Topics: Adult; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Drug Hypersens

1989
Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.
    JAMA, 1986, Oct-03, Volume: 256, Issue:13

    Topics: Acetaminophen; Adult; Aged; Agranulocytosis; Aminopyrine; Analgesics; Anemia, Aplastic; Antipyrine;

1986
[Agranulocytosis caused by medication].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1971, Jun-10, Volume: 91, Issue:16

    Topics: Agranulocytosis; Antithyroid Agents; Female; Humans; Male; Oxyphenbutazone; Phenylbutazone; Sex Fact

1971
[Dangerous medicinal herbs from Eastern Asia].
    Deutsche medizinische Wochenschrift (1946), 1974, Oct-04, Volume: 99, Issue:40

    Topics: Agranulocytosis; Aminopyrine; China; Dosage Forms; Humans; Phenylbutazone; Plant Extracts; Plants; P

1974
[Medicamentous agranulocytosis as a manifestation of drug induced disease].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:1

    Topics: Adult; Agranulocytosis; Aminopyrine; Aspirin; Chloramphenicol; Drug-Related Side Effects and Adverse

1974
[Drug-induced diseases of the mouth and jaw region].
    Deutsche Stomatologie, 1972, Volume: 22, Issue:11

    Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Antineoplastic Agents; Candidiasis, Oral; Dentin; Drug Hy

1972
A study of the effect of some drugs which cause agranulocytosis on the biosynthesis of pyrimidines in human granulocytes.
    Biochemical pharmacology, 1972, Jul-15, Volume: 21, Issue:14

    Topics: Agranulocytosis; Amidohydrolases; Aspartate Carbamoyltransferase; Blood Proteins; Carbimazole; Carbo

1972
[Gold therapy and agranulocytosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Aug-01, Volume: 28, Issue:15

    Topics: Adult; Agranulocytosis; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspir

1973
Investigations of neutropenia using bone marrow culture in semi-solid agar.
    Clinical science and molecular medicine, 1973, Volume: 45, Issue:3

    Topics: Agranulocytosis; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Humans; Methimazole; Neutrophils;

1973
Drug-induced neutropenia-effects of drugs on granulocyte protein synthesis in vitro.
    Clinical science and molecular medicine, 1973, Volume: 45, Issue:3

    Topics: Agranulocytosis; Chloramphenicol; Chlorpromazine; Humans; Leukocytes; Neutrophils; Phenylbutazone; P

1973
The effects of drugs that cause neutropenia upon colony formation by bone marrow cells in semi-solid agar.
    Clinical science and molecular medicine, 1974, Volume: 46, Issue:5

    Topics: Agar; Agranulocytosis; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Chlo

1974
Drug induced agranulocytosis: report of a case.
    Dental images, 1971, Volume: 11, Issue:2

    Topics: Agranulocytosis; Dentistry; Oral Manifestations; Phenylbutazone

1971
The effects of some drugs which induce agranulocytosis on the metabolism of separated human polymorphonuclear leucocytes and lymphocytes.
    British journal of pharmacology, 1970, Volume: 38, Issue:3

    Topics: Agranulocytosis; Aminopyrine; Chloramphenicol; Chlorpromazine; Depression, Chemical; Glucose; Humans

1970
Agranulocytosis: a report of 30 cases.
    Canadian Medical Association journal, 1965, Nov-13, Volume: 93, Issue:20

    Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Aspirin; Bone Marrow; Bone Marrow Examination; Chlorproma

1965
[Drug-induced agranulocytosis with medularry plasmacytosis and hyperglobulinemia].
    Revista clinica espanola, 1966, Nov-30, Volume: 103, Issue:4

    Topics: Adult; Agranulocytosis; Aminopyrine; Antigen-Antibody Reactions; Cerebrospinal Fluid; Humans; Male;

1966