Compounds > phenylbutazone
Page last updated: 2024-11-02

phenylbutazone and Adverse Drug Event

phenylbutazone has been researched along with Adverse Drug Event in 45 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases."1.27[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199041 (91.11)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (6.67)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Sharma, A1
Pagidipati, NJ1
Califf, RM1
McGuire, DK1
Green, JB1
Demets, D1
George, JT1
Gerstein, HC1
Hobbs, T1
Holman, RR1
Lawson, FC1
Leiter, LA1
Pfeffer, MA1
Reusch, J1
Riesmeyer, JS1
Roe, MT1
Rosenberg, Y1
Temple, R1
Wiviott, S1
McMurray, J1
Granger, C1
Haddad, C1
Chosidow, O1
Valeyrie-Allanore, L1
Ghaleh, B1
Legrand, T1
Mockenhaupt, M1
Barau, C1
Khoudour, N1
Sekula, P1
Wolkenstein, P1
Hulin, A1
KHARLASHIN, VI1
Venning, GR1
Wollina, U1
Knipping, W1
Heimpel, H1
Kern, P1
Komakhidze, ME1
Akhmeteli, TI1
Khundadze, SSh1
Dzneladze, LT1
Gvasaliia, GN1
Menguy, R1
Dengler, HJ1
Eichelbaum, M1
Hausmann, K2
Skrandies, G2
Sachtleben, P2
Gnad, HD1
Cooke, AR1
Selby, JV1
Friedman, GD1
Fireman, BH1
Hadnagy, C1
Macavei, I1
Bornuz, F1
Marinca, E1
Sass, G1
Luyckx, A1
Scheen, A1
Van Cauwenberge, H1
Bouletreau, P1
Ducluzeau, R1
Andersson, S1
Fischer, JT1
Gracheva, NM1
McQueen, EG1
Eipe, J1
Fishbein, L1
Flamm, WG1
Wepler, R1
Rommel, K1
Fossati, C1
Kiesewetter, R1
Bartelmann, H1
Belpomme, D1
Blondel, P1
Mathe, G1
Cheli, R1
Ciancamerla, G1
Bruinsma, W1
Shakun, NP1
Oleinik, AN1
Girdwood, RH1
Bode, C1
Martini, GA1
Dodson, WH1
Holley, HL1
Azarnoff, DL1
Gonzalez Campos, C1
Caulin, C1
Jánoska, A1
Sinka, L1
Rintelen, F1
Meyer, JP1
Keiser, G1
Walder, HR1
O'Malley, K1
Crooks, J1
Duke, E1
Stevenson, IH1
Enger, E1

Reviews

7 reviews available for phenylbutazone and Adverse Drug Event

ArticleYear
[Drug-induced panmyelopathies].
    Blut, 1976, Volume: 33, Issue:1

    Topics: Anemia, Aplastic; Antithyroid Agents; Carbutamide; Chloramphenicol; Diseases in Twins; Dose-Response

1976
[Drug-induced immune hemolytic anemias].
    Deutsche medizinische Wochenschrift (1946), 1973, Dec-14, Volume: 98, Issue:50

    Topics: Adsorption; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Antigen-Antibod

1973
Drugs affecting therapy with anticoagulants.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Intera

1972
Potential environmental chemical hazards. I. Drugs.
    The Science of the total environment, 1972, Volume: 1, Issue:1

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Rela

1972
[Drugs and parameters in the laboratory medicine].
    Deutsche medizinische Wochenschrift (1946), 1973, Nov-30, Volume: 98, Issue:48

    Topics: Aminosalicylic Acids; Aspirin; Blood Cell Count; Chlorpromazine; Chlorpropamide; Circadian Rhythm; C

1973
[Liver damage due to drugs. I].
    La Clinica terapeutica, 1974, Jan-15, Volume: 68, Issue:1

    Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re

1974
[Toxic liver injury].
    Medizinische Klinik, 1970, Jan-02, Volume: 65, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Cholestyramine Resin; Contraceptives, Oral; Dia

1970

Other Studies

38 other studies available for phenylbutazone and Adverse Drug Event

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions.
    Circulation, 2020, 03-10, Volume: 141, Issue:10

    Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions;

2020
Are Idiopathic Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Related to Drugs in Food? The Example of Phenylbutazone.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Calibration; Ch

2017
[Side effect of butadion].
    Klinicheskaia meditsina, 1959, Volume: 37, Issue:3

    Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Iatrogenic Disease; Phenylbutazone

1959
Identification of adverse reactions to new drugs. II (continued): How were 18 important adverse reactions discovered and with what delays?
    British medical journal (Clinical research ed.), 1983, Jan-29, Volume: 286, Issue:6362

    Topics: Anemia, Aplastic; Clindamycin; Drug and Narcotic Control; Drug-Related Side Effects and Adverse Reac

1983
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Mar-01, Volume: 39, Issue:5

    Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus

1984
[Problems of evaluating rare adverse drug reactions using as an example agranulocytosis induced by anti-arrhythmia agents].
    Medizinische Klinik, 1980, Feb-01, Volume: 75, Issue:3

    Topics: Aged; Agranulocytosis; Ajmaline; Anti-Arrhythmia Agents; Drug Therapy, Combination; Drug-Related Sid

1980
[Principles of drug therapy. Cumulation].
    MMW, Munchener medizinische Wochenschrift, 1979, Jun-01, Volume: 121, Issue:22

    Topics: Adult; Carbenoxolone; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Hu

1979
[Gastrointestinal hemorrhages as a consequence of the side effects of drug substances].
    Vestnik khirurgii imeni I. I. Grekova, 1977, Volume: 119, Issue:10

    Topics: Aspirin; Blood Volume; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Hem

1977
Gastric mucosal injury from common drugs.
    Postgraduate medicine, 1978, Volume: 63, Issue:4

    Topics: Adrenal Cortex Hormones; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; G

1978
[Polymorphisms and deficient drug metabolism as triggers of toxic reactions (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:96

    Topics: Animals; Antipyrine; Cyclacillin; Diazepam; Drug-Related Side Effects and Adverse Reactions; Humans;

1977
[Current aspects of iatrogenic lesions of the bone marrow].
    Minerva medica, 1976, Nov-14, Volume: 67, Issue:55

    Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol;

1976
[Drugs with unwanted side-effects on the retinal vessels (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1975, Volume: 167, Issue:4

    Topics: Adult; Arterial Occlusive Diseases; Chloramphenicol; Contraceptives, Oral; Drug-Related Side Effects

1975
Drugs and gastric damage.
    Drugs, 1976, Volume: 11, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Buffers; Caffeine; Drug Compounding; Drug-Related Side Effects and

1976
Screening prescription drugs for possible carcinogenicity: eleven to fifteen years of follow-up.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Anti-Bacterial Agents; Atropa belladonna; Carcinogens; Drug-Related Side Effects and Adverse Reactio

1989
[Bone marrow-damaging effect of various drugs].
    Zeitschrift fur arztliche Fortbildung, 1985, Volume: 79, Issue:9

    Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combinatio

1985
[Drug update].
    Revue medicale de Liege, 1985, May-01, Volume: 40, Issue:9

    Topics: Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Oxyphenbutazone; Phenylbutazo

1985
[Present aspects of bone marrow lesions due to drugs (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Sep-20, Volume: 116, Issue:38

    Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse React

1974
[Fatal therapeutic complications].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jun-26, Volume: 45, Issue:30

    Topics: Adult; Aged; Anesthesia, Local; Anti-Bacterial Agents; Anticoagulants; Blood Group Incompatibility;

1969
[Side effects of drugs. 2. Gastrointestinal side effects].
    Lakartidningen, 1969, Dec-15, Volume: 66

    Topics: Adrenocorticotropic Hormone; Caffeine; Drug-Related Side Effects and Adverse Reactions; Gastrointest

1969
[Medicamentous agranulocytosis as a manifestation of drug induced disease].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:1

    Topics: Adult; Agranulocytosis; Aminopyrine; Aspirin; Chloramphenicol; Drug-Related Side Effects and Adverse

1974
New Zealand Committee on Adverse Drug Reactions: Ninth Annual Report 1974.
    The New Zealand medical journal, 1974, Oct-09, Volume: 80, Issue:525

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Antineoplastic Agents; Drug Interactions; Drug

1974
[Drug side-effects and interferences in a selected patient material from an internal hospital].
    Zeitschrift fur arztliche Fortbildung, 1972, Oct-01, Volume: 66, Issue:19

    Topics: Anti-Bacterial Agents; Anticoagulants; Barbiturates; Digitalis Glycosides; Drug Antagonism; Drug Int

1972
[Cancer of therapeutic origin].
    La Vie medicale au Canada francais, 1972, Volume: 1, Issue:2

    Topics: Animals; Antineoplastic Agents; Cyclamates; Drug-Related Side Effects and Adverse Reactions; Female;

1972
[Gastric erosions and ulcerations in gastritis caused by drugs].
    Zeitschrift fur Gastroenterologie, 1972, Volume: 10, Issue:8

    Topics: Aminopyrine; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastritis; Gastroscopy; Gluco

1972
Adverse reaction profiles of drug eruptions.
    Dermatologica, 1972, Volume: 145, Issue:6

    Topics: Ampicillin; Analgesics; Aspirin; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Er

1972
[Effect of drugs on bilirubin metabolism in the treatment of jaundice].
    Vrachebnoe delo, 1973, Volume: 11

    Topics: Bilirubin; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Humans; Hyperbilirubine

1973
Death after taking medicaments.
    British medical journal, 1974, Mar-16, Volume: 1, Issue:5906

    Topics: Adrenal Cortex Hormones; Analgesics; Anti-Bacterial Agents; Antidepressive Agents; Aspirin; Chlorpro

1974
Iatrogenic disease in the treatment of rheumatoid arthritis.
    Journal of the Medical Association of the State of Alabama, 1971, Volume: 41, Issue:3

    Topics: Arthritis, Rheumatoid; Chloroquine; Drug-Related Side Effects and Adverse Reactions; Glucocorticoids

1971
Clinical implications of drug metabolism--introduction.
    Chemico-biological interactions, 1971, Volume: 3, Issue:4

    Topics: Drug Interactions; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceut

1971
[Iatrogenic hemorrhage].
    Revista espanola de las enfermedades del aparato digestivo, 1968, Volume: 27, Issue:2

    Topics: Anticoagulants; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal Hemorrhag

1968
[Digestive disorders from drug origin. I. Gastrointestinal lesions].
    La Presse medicale, 1971, Nov-06, Volume: 79, Issue:47

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticoagulants; Aspirin; C

1971
[Bullous drug exanthemata with special regard to toxic epidermal necrolysis (Lyell)].
    Ceskoslovenska dermatologie, 1969, Volume: 44, Issue:5

    Topics: Adult; Aged; Aminopyrine; Blister; Drug-Related Side Effects and Adverse Reactions; Erythema; Female

1969
[Realization of nonocular dangers resulting from general medical therapy in ocular affections].
    Klinische Monatsblatter fur Augenheilkunde, 1970, Volume: 156, Issue:2

    Topics: Acetazolamide; Aged; Anticoagulants; Diuretics; Drug-Related Side Effects and Adverse Reactions; Ede

1970
[Idiopathic and drug-induced acquired aplastic anemia].
    Schweizerische medizinische Wochenschrift, 1970, Apr-18, Volume: 100, Issue:16

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Androgens; Anemia, Aplastic; Blood Transfusion; Chloramp

1970
Effect of age and sex on human drug metabolism.
    British medical journal, 1971, Sep-11, Volume: 3, Issue:5775

    Topics: Adolescent; Adult; Age Factors; Aged; Antipyrine; Drug-Related Side Effects and Adverse Reactions; F

1971
[Drug-induced kidney lesions].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968, Jan-01, Volume: 88, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Contrast Media; Drug Tolerance; Drug-Related Side Effects and Adverse R

1968