Page last updated: 2024-11-02

phenylbutazone and Adjuvant Arthritis

phenylbutazone has been researched along with Adjuvant Arthritis in 54 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
"Daily oral administration of 6-mercaptopurine suppressed the development of the secondary (immune) lesions of adjuvant arthritis in a dose-related manner."7.65Mechanisms underlying the suppression of adjuvant-induced arthritis by 6-mercaptopurine. ( Chang, YH, 1977)
"Tilorone (5-35 mg/kg/day) suppressed the development of adjuvant-induced arthritis and the concurrent development of cell-mediated immune response to a secondary immunogen(EL4 cells) in a dose-related manner."7.65Adjuvant polyarthritis. II. Suppression by tilorone. ( Chang, YH, 1977)
"A series of 2-substituted- and 2,3-disubstituted-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-1H- pyrroles was synthesized and found to be active in the rat adjuvant arthritis model of inflammation."3.69Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR. ( Galbraith, W; Gans-Brangs, K; Grubb, M; Hewes, WE; Jaffee, B; Kenney, JP; Kerr, J; Wilkerson, WW; Wong, N, 1994)
" In chronic models of formaldehyde and adjuvant arthritis, its anti-arthritic activity was found to be less than that of phenylbutazone (PNB)."3.69Anti-inflammatory activity of the bark of Hippocratea excelsa. ( Perez, RM; Perez, S; Salazar, M; Zavala, MA, 1995)
"Replacement of the carboxyl group of 2-(3-benzoylphenyl)propionic acid (Ketoprofen) with various bulky amines has produced a series of highly active antiinflammatory agents that have reduced intestinal ulcerogenicity and have better therapeutic ratios in the 21-day adjuvant arthritis assay in rats than currently marketed nonsteroidal antiinflammatory drugs."3.67Bulky amine analogues of ketoprofen: potent antiinflammatory agents. ( Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL, 1984)
"Sequential potentiation of antiinflammatory activity of dexamethasone was obtained by co-administration of diclofenac-Na (and indomethacin), but not of phenylbutazone and, apparently, of acetylsalicylic acid (ASA) in the carrageenin rat paw edema."3.67On steroid-saving drug combinations in carrageenin paw edema and adjuvant arthritis. ( Bekemeier, H; Hirschelmann, R, 1986)
" The most potent compound synthesized, 1-(4-chlorophenyl)-3-isoquinolineacetamide, was as active as phenylbutazone in the Evans blue carrageenan-induced pleural effusion assay but inactive in the adjuvant-induced arthritis model of chronic inflammation."3.66Aroyl- and arylisoquinolineacetic acids as antiinflammatory agents. ( Reese, DL; Sancilio, LF; Walsh, DA, 1978)
" Anti-edema activities of M-7074 were more potent than those of phenylbutazone in carrageenin, bradykinin and mustard edema tests in rats."3.66Anti-inflammatory properties of a newly synthesized compound, 6-chloro-4-oxyimino-1-phenyl-1,2,3,4-tetrahydroquinoline (M-7074). ( Kosuzume, H; Ohkura, M; Ohnishi, H; Satoh, M; Suzuki, Y; Toyonaka, Y; Uohama, M; Yamaguchi, K, 1981)
" The anti-inflammatory activity of Indomethacin, Oxametacine and Phenylbutazone was evaluated in these animals using paw oedema provoked by carrageenan granulomas induced by cotton pellets and polyarthritis induced by Freund complete adjuvant."3.66The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents. ( Cirillo, R; Curzio, M; Franzone, J; Sena, L; Torrielli, MV, 1981)
" The potency of topical piroxicam exceeds that of topically applied bufexamac or phenylbutazone in the rat adjuvant arthritis model."3.66The topical anti-inflammatory effects of piroxicam in rodents. ( Larson, DL; Lombardino, JG, 1980)
"Daily oral administration of 6-mercaptopurine suppressed the development of the secondary (immune) lesions of adjuvant arthritis in a dose-related manner."3.65Mechanisms underlying the suppression of adjuvant-induced arthritis by 6-mercaptopurine. ( Chang, YH, 1977)
"Both developing (Days --1-+12 relative to inoculation) and established (Days +18-+29) stages of Mycobacterium butyricum adjuvant-induced polyarthritis in rats were treated orally with cryogenine (100 mg/kg/day), a prototype anti-inflammatory (phenylbutazone, 100 mg/kg/day), or a prototype immunosuppressive (cyclophosphamide, 6 mg/kg/day)."3.65Evaluation of immunosuppressive potential of cryogenine using developing and established adjuvant arthritis in rats. ( Malone, MH; Watson, WC, 1977)
"Tilorone (5-35 mg/kg/day) suppressed the development of adjuvant-induced arthritis and the concurrent development of cell-mediated immune response to a secondary immunogen(EL4 cells) in a dose-related manner."3.65Adjuvant polyarthritis. II. Suppression by tilorone. ( Chang, YH, 1977)
" Five pharmacodynamic end-points were regularly measured after test article injection using standardized procedures: local skin temperature, stride length, the rest angle flexion and the maximal carpal flexion of the injured leg and circumference of the inflamed joint."1.29Plasma concentrations and therapeutic efficacy of phenylbutazone and flunixin meglumine in the horse: pharmacokinetic/pharmacodynamic modelling. ( Alvinerie, M; Autefage, A; Legrand, C; Toutain, PL, 1994)
" Results show that the drug exhibiting almost no antiinflammatory activity in the rat at the dosage used, phenylbutazone, was the most powerful inhibitor of ossification."1.27Correlation between ossification and inflammation using a rat experimental model. ( de Medicis, R; Lussier, A, 1983)
"None was active in the adjuvant arthritis model."1.26Synthesis and antiinflammatory activity of trisubstituted pyrimidines and triazines. ( Alden, LJ; Bennett, GB; Mason, RB; Roach, JB, 1978)
" It was found that compounds with polar substituents at the 2 or 3 position of the ring system are less acutely toxic while maintaining antiinflammatory activity."1.26Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles. ( Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ, 1981)
"Etodolac was 2."1.26Comparison in rats of the anti-inflammatory and gastric irritant effects of etodolac with several clinically effective anti-inflammatory drugs. ( Klicius, J; Martel, RR, 1982)
" These results suggest that Y-8004 may make feasible a reduction in dosage or a withdrawal of the steroid prescription."1.26[Pharmacological studies of 2-(5H-(1)benzopyrano[2,3-b]pyridin-7-yl)propionic acid (Y-8004). (3) Its interaction with anti-inflammatory agents]. ( Foto, K; Imayoshi, T; Kadobe, Y; Maruyama, Y, 1977)
"A modified model of adjuvant arthritis is described that permits simultaneous quantitative measurement of the humoral and the cellular immune response to a secondary immunogen (el4 cells) in the arthritic rat."1.26Adjuvant polyarthritis I: incorporation of quantitative measurements of humoral and cellular immune response. ( Chang, YH, 1977)
"Butibufen was within the potency range of ibuprofen as an antipyretic and analgesic agent and greater than that of acetylsalicylic acid."1.26Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent. ( Aparicio, L, 1977)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199044 (81.48)18.7374
1990's8 (14.81)18.2507
2000's2 (3.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clark, RL1
Pessolano, AA1
Witzel, B1
Lanza, T1
Shen, TY1
Van Arman, CG1
Risley, EA1
Nagakura, M1
Ota, T1
Shimidzu, N1
Kawamura, K1
Eto, Y1
Wada, Y1
Welstead, WJ1
Moran, HW1
Stauffer, HF1
Turnbull, LB1
Sancilio, LF2
Smith, CE1
Williamson, WR1
Cashin, CH2
Kitchen, EA2
Walsh, DA1
Reese, DL1
Bennett, GB1
Mason, RB1
Alden, LJ1
Roach, JB1
Buckler, RT1
Hartzler, HE1
Kurchacova, E1
Nichols, G1
Phillips, BM1
Sharpe, TR1
Cherkofsky, SC1
Hewes, WE2
Smith, DH1
Gregory, WA1
Haber, SB1
Leadbetter, MR1
Whitney, JG1
Schlegel, DC1
Zenitz, BL1
Fellows, CA1
Laskowski, SC1
Behn, DC1
Phillips, DK1
Botton, I1
Speight, PT1
Toja, E1
Selva, D1
Schiatti, P1
Powers, LJ1
Fogt, SW1
Ariyan, ZS1
Rippin, DJ1
Heilman, RD1
Matthews, RJ1
Houlihan, WJ1
Cooke, G1
Van Bochoven, R1
Perrine, J1
Takesue, EI1
Jukniewicz, E1
Wilkerson, WW1
Galbraith, W1
Gans-Brangs, K1
Grubb, M1
Jaffee, B1
Kenney, JP1
Kerr, J1
Wong, N1
Kontogiorgis, CA1
Hadjipavlou-Litina, DJ1
HERSHBERGER, LG1
CHEMNITIUS, KH1
KLEE, H1
REIHL, G1
NEWBOULD, BB1
Adak, M1
Gupta, JK1
Martel, RR1
Klicius, J1
Lussier, A1
de Medicis, R1
Villar, A1
Salom, R1
Alcaraz, MJ1
Schmollack, W1
Phuoc, LT1
Bekemeier, H2
Janků, I1
Perlik, F1
Seifert, J1
Ohnishi, H1
Kosuzume, H1
Yamaguchi, K1
Ohkura, M1
Satoh, M1
Uohama, M1
Toyonaka, Y1
Suzuki, Y1
Elis, J1
Kameníková, L1
Sena, L1
Torrielli, MV1
Franzone, J1
Curzio, M1
Cirillo, R1
Larson, DL1
Lombardino, JG1
Perez, RM1
Perez, S1
Zavala, MA1
Salazar, M1
Toutain, PL1
Autefage, A1
Legrand, C1
Alvinerie, M1
Vigorita, MG1
Grasso, S1
Zappalà, M1
Ottanà, R1
Monforte, MT1
Barbera, R1
Trovato, A1
St Papadopulos, J1
Liapi, CA1
Dawson, W1
Binderup, L1
Bramm, E1
Arrigoni-Martelli, E1
Engelhardt, G1
Swingle, KF1
Grant, TJ1
Fujihira, E1
Sandeman, VA1
Whitehouse, MW1
Maruyama, Y1
Imayoshi, T1
Foto, K1
Kadobe, Y1
Sharma, JN2
Jones, RC1
Datko, LJ1
Beascoa, E1
Giráldez, A1
Llenas, J1
Zapatero, J1
Bruseghini, L1
Chang, YH3
Sofia, RD1
Aparicio, L1
Watson, WC1
Malone, MH1
Shriver, DA1
Dove, PA1
White, CB1
Sandor, A1
Rosenthale, ME1
Grau, M1
Guasch, J1
Montero, JL1
Felipe, A1
Carrasco, E1
Juliá, S1
Frechilla, D1
Lasheras, B1
Ucelay, M1
Parrondo, E1
Craciunescu, G1
Cenarruzabeitia, E1
Ray, SM1
Roy, A1
Lahiri, SC1
Singh, B1
Gambhir, SS1
Pandey, VB1
Joshi, VK1
Hirschelmann, R1
Fujiyoshi, T1
Iida, H1
Saito, M1
Ikeda, K1
Yamaura, T1
Uematsu, T1
Connolly, K1
Stecher, VJ1
Kaplan, JE1
Mielens, Z1
Rostami, HJ1
Saelens, JK1

Reviews

1 review available for phenylbutazone and Adjuvant Arthritis

ArticleYear
[Effect of non-steroidal anti-inflammatory drugs on plasma protein binding of corticosterones (author's transl)].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:10

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blo

1978

Other Studies

53 other studies available for phenylbutazone and Adjuvant Arthritis

ArticleYear
2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1978
Syntheses and antiinflammatory actions of 4,5,6,7-tetrahydroindazole-5-carboxylic acids.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema; Indazole

1979
Antiinflammatory agents. 1. Synthesis and antiinflammatory activity of 2-amino-3-benzoylphenylacetic acid.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Benzophenones; Biotransformation; Female

1979
Potential antiinflammatory compounds. 3. Compounds derived from acenaphthene and indan.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:12

    Topics: Acenaphthenes; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema; Indan

1979
Aroyl- and arylisoquinolineacetic acids as antiinflammatory agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Isoquinolines; Phenylbutazone; Pleural E

1978
Synthesis and antiinflammatory activity of trisubstituted pyrimidines and triazines.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema; Pyrimidines; Rats; S

1978
Synthesis and antiinflammatory activity of some 1,2,3- and 1,2,4-triazolepropionic acids.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Male; Pleural Effusion; Propionates; Rat

1978
Preparation and antiarthritic and analgesic activity of 4,5-diaryl-2-(substituted thio)-1H-imidazoles and their sulfoxides and sulfones.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chemical Phenomena

1985
Bulky amine analogues of ketoprofen: potent antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Eval

1984
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclini

1984
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1981
Antiinflammatory properties of 8-aryl-5-isopropyl-2H-1,3-dioxolo[4,5-g]quinazolin-6(5H)-ones and -thiones.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Bradykinin; Carrageenan; Chemical Phenom

1982
Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR.
    Journal of medicinal chemistry, 1994, Apr-01, Volume: 37, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Models, Animal; D

1994
Synthesis and antiinflammatory activity of coumarin derivatives.
    Journal of medicinal chemistry, 2005, Oct-06, Volume: 48, Issue:20

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Coumarins; C

2005
Effects of cortisol and phenylbutazone on experimental arthritis and serum polysaccharide/protein ratios in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 99, Issue:1

    Topics: Animals; Arthritis, Experimental; Blood Proteins; Dietary Carbohydrates; Hydrocortisone; Phenylbutaz

1958
[Serum protein changes in formalin-arthritic rats under the action of antirheumatic agents].
    Zeitschrift fur Rheumaforschung, 1961, Volume: 20

    Topics: Aminopyrine; Animals; Antirheumatic Agents; Arthritis, Experimental; Blood Proteins; Formaldehyde; P

1961
SUPPRESSION OF ADJUVANT-INDUCED ARTHRITIS IN RATS WITH 2-BUTOXYCARBONYLMETHYLENE-4-OXOTHIAZOLIDINE.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Binding Sites; Carrageenan; F

1965
Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological system.
    Nepal Medical College journal : NMCJ, 2006, Volume: 8, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Calotropis; Chronic Disease; Edema; Home

2006
Comparison in rats of the anti-inflammatory and gastric irritant effects of etodolac with several clinically effective anti-inflammatory drugs.
    Agents and actions, 1982, Volume: 12, Issue:3

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Etodolac; Gastric Mucosa; Irri

1982
Correlation between ossification and inflammation using a rat experimental model.
    The Journal of rheumatology. Supplement, 1983, Volume: 11

    Topics: Animals; Arthritis; Arthritis, Experimental; Disease Models, Animal; Indomethacin; Naproxen; Ossific

1983
Effect of borjatriol on established adjuvant arthritis.
    Die Pharmazie, 1983, Volume: 38, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Body Weight; Diterpenes; Fema

1983
The influence of phenylbutazone on the zinc level in serum and paw tissue of rats with adjuvant arthritis.
    Agents and actions. Supplements, 1982, Volume: 10

    Topics: Animals; Arthritis; Arthritis, Experimental; Copper; Female; Foot; Iron; Phenylbutazone; Rats; Rats,

1982
Lack of correlation between induction of adjuvant arthritis and changes in metabolism and disposition of phenylbutazone in rats.
    Pharmacology, 1980, Volume: 20, Issue:3

    Topics: Animals; Arthritis; Arthritis, Experimental; Cytochrome P-450 Enzyme System; Cytochromes; Male; Micr

1980
Anti-inflammatory properties of a newly synthesized compound, 6-chloro-4-oxyimino-1-phenyl-1,2,3,4-tetrahydroquinoline (M-7074).
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:5

    Topics: Aminoquinolines; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroi

1981
[The effect of adjuvant arthritis on the tribuzone levels in the blood of rats].
    Ceskoslovenska farmacie, 1981, Volume: 30, Issue:2

    Topics: Animals; Arthritis; Arthritis, Experimental; Male; Phenylbutazone; Rats

1981
The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents.
    The Journal of pathology, 1981, Volume: 135, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema;

1981
The topical anti-inflammatory effects of piroxicam in rodents.
    Agents and actions, 1980, Volume: 10, Issue:3

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis, Experim

1980
Anti-inflammatory activity of the bark of Hippocratea excelsa.
    Journal of ethnopharmacology, 1995, Jul-07, Volume: 47, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1995
Plasma concentrations and therapeutic efficacy of phenylbutazone and flunixin meglumine in the horse: pharmacokinetic/pharmacodynamic modelling.
    Journal of veterinary pharmacology and therapeutics, 1994, Volume: 17, Issue:6

    Topics: Animals; Arthritis, Experimental; Clonixin; Dose-Response Relationship, Drug; Female; Horses; Male;

1994
Aminopyrazinyl derivatives: synthesis and evaluation of antiinflammatory and related activities.
    Farmaco (Societa chimica italiana : 1989), 1994, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Edema; Femal

1994
Lethal dose curve: should its determination be made in healthy or in animal models of disease?
    Drug and chemical toxicology, 1999, Volume: 22, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Models, Animal; M

1999
The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Arthritis, Experimental; Benzoxazo

1977
Characterization of inhibitor(s) of lymphocyte activation in serum from rats with adjuvant arthritis.
    Pharmacology, 1978, Volume: 17, Issue:5

    Topics: Animals; Arthritis; Arthritis, Experimental; Chemical Fractionation; Chromatography, Gel; Concanaval

1978
Evaluation of some standard arthritogenic adjuvants ('modified perrigens') in male rats.
    Agents and actions, 1977, Volume: 7, Issue:4

    Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Cyclophosphamide; Male; Mycobacterium; Myc

1977
Pathobiodynamics: reduction in hepatic and intestinal ligandin (glutathione-S-transferase) levels in rats with severe acute and chronic inflammation.
    Biochemical medicine, 1979, Volume: 22, Issue:2

    Topics: Animals; Arthritis; Arthritis, Experimental; Copper; Cytosol; Glutathione Transferase; Indomethacin;

1979
[Pharmacological studies of 2-(5H-(1)benzopyrano[2,3-b]pyridin-7-yl)propionic acid (Y-8004). (3) Its interaction with anti-inflammatory agents].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Dose-Response Relationship, Dru

1977
Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Female; Ibuprofen; Male; Myco

1977
Administration of anti-inflammatory compounds in silastic capsules.
    Agents and actions, 1977, Volume: 7, Issue:5-6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capsules; Indometh

1977
[Pharmacology of a new derivative with anti-inflammatory activity: ITA 194].
    Archivos de farmacologia y toxicologia, 1978, Volume: 4, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dogs; Feprazone; Gastric Muco

1978
Adjuvant polyarthritis I: incorporation of quantitative measurements of humoral and cellular immune response.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 201, Issue:1

    Topics: Animals; Arthritis; Arthritis, Experimental; Azathioprine; Cell Line; Cyclophosphamide; Edema; Freun

1977
Mechanisms underlying the suppression of adjuvant-induced arthritis by 6-mercaptopurine.
    Arthritis and rheumatism, 1977, Volume: 20, Issue:5

    Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Carrageenan; Cell Line; Cyclophosph

1977
Alteration of Hepatic microsomal enzyme systems and the lethal action of non-steroidal anti-arthritic drugs in acute and chronic models of inflammation.
    Agents and actions, 1977, Volume: 7, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Carrageenan; Chr

1977
Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 227, Issue:1

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Gr

1977
Evaluation of immunosuppressive potential of cryogenine using developing and established adjuvant arthritis in rats.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:9

    Topics: Alkaloids; Animals; Arthritis; Arthritis, Experimental; Cyclophosphamide; Immunosuppressive Agents;

1977
Adjuvant polyarthritis. II. Suppression by tilorone.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:1

    Topics: Animals; Arthritis; Arthritis, Experimental; Cell Line; Fluorenes; Immunity; Immunity, Cellular; Inf

1977
A profile of the gastrointestinal toxicity of aspirin, indomethacin, oxaprozin, phenylbutazone, and fentiazac in arthritic and Lewis normal rats.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:1

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Aspirin; Body Weigh

1977
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary

1991
Anti-inflammatory activity of some copper(II) complexes.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

1990
Studies on non-steroidal anti-inflammatory and related biological activities of 5-(indan-1'-yl)tetrazoles and their intermediates.
    Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Carrageenan; Ede

1990
Anti-inflammatory activity of Echinops echinatus.
    Journal of ethnopharmacology, 1989, Volume: 25, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema

1989
On steroid-saving drug combinations in carrageenin paw edema and adjuvant arthritis.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Dexame

1986
[The analgesic and antipyretic effects of a non-steroidal antiinflammatory agent, EB-382, in experimental animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Ibuprofen; Indom

1986
The effect of antiinflammatory drugs on plasma fibronectin.
    The Journal of rheumatology, 1985, Volume: 12, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Aspirin; Fibronectins; Indome

1985