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phenylbutazone and Acute Kidney Injury

phenylbutazone has been researched along with Acute Kidney Injury in 29 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Two patients had phenylbutazone-induced systemic vasculitis syndrome."7.67Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. ( Dobbie, JW; Jones, JM; Leung, AC; McLay, A, 1985)
"Acute oliguric renal failure due to acute interstitial nephritis developed in a patient after treatment with phenylbutazone."7.66[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication]. ( Briner, J; Fontana, A; Kuhlmann, U; Siegenthaler, W; Steinemann, U, 1978)
"Two patients had phenylbutazone-induced systemic vasculitis syndrome."3.67Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis. ( Dobbie, JW; Jones, JM; Leung, AC; McLay, A, 1985)
"Acute oliguric renal failure due to acute interstitial nephritis developed in a patient after treatment with phenylbutazone."3.66[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication]. ( Briner, J; Fontana, A; Kuhlmann, U; Siegenthaler, W; Steinemann, U, 1978)
"Phenylbutazone is a nonsteroidal anti-inflammatory drug that was commonly prescribed for the treatment of arthritic conditions; it is no longer available for use in humans because of its numerous side effects, including aplastic anemia."1.29Misuse of veterinary phenylbutazone. ( Carpenter, SL; McDonnell, WM, 1995)
"Phenylbutazone is a potent nonsteroidal, anti-inflammatory drug often used by veterinarians to treat racetrack animals."1.28Poisoning with equine phenylbutazone in a racetrack worker. ( Newton, TA; Rose, SR, 1991)
" Due to many different pharmacokinetic properties, no perfect rules for dosage in acute or chronic hemodialysis exist."1.27Tranquilizers, analgetics and antidepressants in patients treated with hemodialysis. ( Forycki, Z; Ibe, K; Martens, F; Thalhofer, S, 1985)
"For phenylbutazone serum binding was decreased in uraemic rabbits, while the binding in homogenates of kidneys and liver was increased."1.26Binding of drugs in serum, blood cells and tissues of rabbits with experimental acute renal failure. ( Belpaire, FM; Bogaert, MG; Van Peer, AP, 1981)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199027 (93.10)18.7374
1990's2 (6.90)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LIPSETT, MB1
GOLDMAN, R1
BOLTON, R1
BARRIE, H1
RICHARDSON, JH1
ALDERFER, HH1
STREICHER, E1
Dunea, G1
Muehrcke, RC1
Nakamoto, S1
Schwartz, FD1
Robertson, C1
Innes, S1
Paton, J1
Clive, DM1
Stoff, JS1
Doyle, GD1
Campbell, E1
Gavin, N1
Garrett, P1
Carmody, M1
Smyk, T1
Ksiazek, A1
Banach, L1
Greenstone, M1
Hartley, B1
Gabriel, R1
Bevan, G1
Van Peer, AP2
Belpaire, FM4
Rosseel, MT1
Bogaert, MG4
Carpenter, SL1
McDonnell, WM1
Kuhlmann, U1
Fontana, A1
Briner, J1
Steinemann, U1
Siegenthaler, W1
Kimberly, RP1
Brandstetter, RD1
Van Peer, A1
Belpaire, F2
Bogaert, M2
Mussche, MM2
De Broe, M1
Mussche, M1
Newton, TA1
Rose, SR1
Forycki, Z1
Martens, F1
Thalhofer, S1
Ibe, K1
Leung, AC1
McLay, A1
Dobbie, JW1
Jones, JM1
Hirsch, S1
Dobrecki, J1
Hanicki, Z1
Zelazny, T1
Hirszel, P1
Pajdak, W1
Zebro, T1
Andreasen, F1
MacLennan, WJ1
Wajcner, G1
Guedon, J1
Chapman, A1
Domanasiewicz, M1
Lewandowska, J1

Reviews

1 review available for phenylbutazone and Acute Kidney Injury

ArticleYear
Renal syndromes associated with nonsteroidal antiinflammatory drugs.
    The New England journal of medicine, 1984, Mar-01, Volume: 310, Issue:9

    Topics: Acute Kidney Injury; Adult; Animals; Anti-Inflammatory Agents; Anuria; Aspirin; Body Water; Electrol

1984

Other Studies

28 other studies available for phenylbutazone and Acute Kidney Injury

ArticleYear
Phenylbutazone toxicity: report of a case of acute renal failure.
    Annals of internal medicine, 1954, Volume: 41, Issue:5

    Topics: Acute Kidney Injury; Analgesics; Humans; Kidney Diseases; Phenylbutazone

1954
Acute renal failure after phenylbutazone.
    British medical journal, 1955, Feb-05, Volume: 1, Issue:4909

    Topics: Acute Kidney Injury; Analgesics; Arthritis; Humans; Kidney Diseases; Phenylbutazone

1955
Acute renal failure caused by phenylbutazone.
    The New England journal of medicine, 1963, Apr-11, Volume: 268

    Topics: Acute Kidney Injury; Humans; Phenylbutazone

1963
[ACUTE RENAL FAILURE FOLLOWING THERAPEUTIC USE OF PHENYLBUTAZONE].
    Deutsche medizinische Wochenschrift (1946), 1964, Feb-28, Volume: 89

    Topics: Acute Kidney Injury; Phenylbutazone; Renal Insufficiency; Toxicology

1964
Thrombotic thrombocytopenic purpura with acute anuric renal failure.
    The American journal of medicine, 1966, Volume: 41, Issue:6

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Anuria; Diagnosis, Differential; Female; Humans; Phen

1966
Renal failure complicating feprazone treatment.
    Human toxicology, 1981, Volume: 1, Issue:1

    Topics: Acute Kidney Injury; Aged; Drug Eruptions; Feprazone; Humans; Male; Phenylbutazone

1981
Phenylbutazone nephrotoxicity--a light and electron microscopic study.
    Irish journal of medical science, 1983, Volume: 152, Issue:12

    Topics: Acute Kidney Injury; Adult; Biopsy; Humans; Kidney; Male; Phenylbutazone

1983
[Kidney damage after treatment with butapyrazole].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1983, Nov-15, Volume: 36, Issue:22

    Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents; Humans; Male; Nephritis, Interstitial; P

1983
Acute nephrotic syndrome with reversible renal failure after phenylbutazone.
    British medical journal (Clinical research ed.), 1981, Mar-21, Volume: 282, Issue:6268

    Topics: Acute Kidney Injury; Aged; Humans; Kidney Glomerulus; Male; Microscopy, Electron; Nephrotic Syndrome

1981
Distribution of antipyrine, phenylbutazone and phenytoin in experimental renal failure.
    Pharmacology, 1981, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Proteins; Female; Phenylbutazone; Phenytoin; Protein

1981
Binding of drugs in serum, blood cells and tissues of rabbits with experimental acute renal failure.
    Pharmacology, 1981, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Cells; Blood Proteins; Female; Phenylbutazone; Pheny

1981
Misuse of veterinary phenylbutazone.
    Archives of internal medicine, 1995, Jun-12, Volume: 155, Issue:11

    Topics: Acute Kidney Injury; Humans; Male; Middle Aged; Phenylbutazone; Self Medication; Stomach Ulcer; Vete

1995
[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication].
    Schweizerische medizinische Wochenschrift, 1978, Apr-01, Volume: 108, Issue:13

    Topics: Acute Kidney Injury; Adult; Back Pain; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Dela

1978
Exacerbation of phenylbutazone-related renal failure by indomethacin.
    Archives of internal medicine, 1978, Volume: 138, Issue:11

    Topics: Acute Kidney Injury; Aged; Blood Urea Nitrogen; Creatinine; Female; Humans; Indomethacin; Phenylbuta

1978
Pharmacokinetics of drugs in rabbits with experimental acute renal failure.
    Pharmacology, 1978, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Proteins; Female; Half-Life; Phenylbutazone; Phenyto

1978
Clinicopathological Conference. Diagnostic difficulties in a case of polypharmacy. Demonstrated at the Royal College of Physicians of London.
    British medical journal, 1977, Jan-22, Volume: 1, Issue:6055

    Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Hepatitis, Vir

1977
Influence of acute renal failure on the protein binding of drugs in animals and in man.
    European journal of clinical pharmacology, 1977, Volume: 11, Issue:1

    Topics: Acute Kidney Injury; Animals; Blood Proteins; Cats; Digitoxin; Dogs; Female; Guinea Pigs; Humans; Ma

1977
Serum binding of quinidine in experimental acute renal failure.
    Pharmacology, 1977, Volume: 15, Issue:4

    Topics: Acute Kidney Injury; Animals; Binding Sites; Esophagus; Ligation; Male; Papaverine; Phenylbutazone;

1977
Plasma protein binding of phenylbutazone during recovery from acute renal failure.
    European journal of clinical pharmacology, 1975, Oct-10, Volume: 9, Issue:1

    Topics: Acute Kidney Injury; Aged; Blood Proteins; Diuresis; Female; Humans; In Vitro Techniques; Kidney Tub

1975
Poisoning with equine phenylbutazone in a racetrack worker.
    Annals of emergency medicine, 1991, Volume: 20, Issue:2

    Topics: Acute Kidney Injury; Adult; Animals; Chemical and Drug Induced Liver Injury; Coma; Dogs; Drug Overdo

1991
Tranquilizers, analgetics and antidepressants in patients treated with hemodialysis.
    Blood purification, 1985, Volume: 3, Issue:1-3

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Benzodia

1985
Phenylbutazone-induced systemic vasculitis with crescentic glomerulonephritis.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Acute Kidney Injury; Aged; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Glomerulonep

1985
[Acute renal failure in the course of treatment with drugs of the phenylbutazone group].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1973, Jul-01, Volume: 26, Issue:13

    Topics: Acute Kidney Injury; Female; Humans; Middle Aged; Pain; Phenylbutazone

1973
[Acute renal insufficiency following butapyrazole treatment in the course of plasmatic cell leukemia (author's transl)].
    Przeglad lekarski, 1973, Volume: 30, Issue:11

    Topics: Acute Kidney Injury; Adult; Autopsy; Humans; Kidney; Leukemia, Plasma Cell; Male; Phenylbutazone; Th

1973
Protein binding of drugs in plasma from patients with acute renal failure.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Acute Kidney Injury; Aged; Aspirin; Blood Proteins; Female; Humans; In Vitro Techniques; Male; Middl

1973
Drug interactions.
    Gerontologia clinica, 1974, Volume: 16, Issue:1

    Topics: 1-Propanol; Acute Kidney Injury; Aged; Albumins; Antidepressive Agents; Antihypertensive Agents; Ben

1974
[Acute anuric renal insufficiency with necrosing arteriolitis. Etiologic problems].
    Journal d'urologie et de nephrologie, 1968, Volume: 74, Issue:9

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Angioedema; Anuria; Arteritis; Arthritis; Aspirin; Dr

1968
[Acute renal insufficiency and toxic damage of the liver in the course of poisoning with reumopirin in a 4 1/2-year-old girl].
    Przeglad lekarski, 1966, Volume: 22, Issue:4

    Topics: Acute Kidney Injury; Aminopyrine; Child, Preschool; Female; Humans; Phenylbutazone

1966