phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with Thrombosis in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 18 (62.07) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Myerson, JW; Palekar, RU; Pan, H; Sadler, JE; Schlesinger, PH; Wickline, SA | 1 |
| Arif, B; Marsh, JN; Palekar, RU; Vemuri, C; Wickline, SA | 1 |
| Jallouk, AP; Myerson, JW; Palekar, RU; Pan, H; Wickline, SA | 1 |
| Brass, LF; Diamond, SL; Maloney, SF | 1 |
| He, L; Lanza, G; Myerson, J; Tollefsen, D; Wickline, S | 1 |
| Deckmyn, H; Farndale, RW; Heemskerk, JW; Lindhout, T; Munnix, IC; Ouwehand, WH; Siljander, PR; Smethurst, PA | 1 |
| André, P; Conley, PB; Delaney, SM; LaRocca, T; Lin, PH; Phillips, DR; Sinha, U; Vincent, D | 1 |
| Arnljots, B; Dahlbäck, B | 1 |
| Clas, DM; Dundore, RL; Habeeb, PG; Pagani, ED; VanAller, GS | 1 |
| Frey, L; Hancock, T; Hollenbach, S; Lin, PH; Needham, K; Sinha, U; Wolf, D; Wong, A | 1 |
| Sefton, MV | 1 |
| Brash, JL; Kinlough-Rathbone, RL; Rubens, FD; Weitz, JI | 1 |
| Dodson, T; Hanson, SR; Harker, LA; Kelly, AB; Krupski, WC; Lumsden, AB; Schneider, PA | 1 |
| Matsuoka, A; Sasaki, Y; Yamamoto, J; Yamashita, T | 1 |
| Fenton, JW | 1 |
| Carpen, O; Lassila, R; Siljander, P | 1 |
| Chen, D; Dorling, A; George, AJ; Kemball-Cook, G; Lechler, RI; McVey, JH; Riesbeck, K; Tuddenham, EG | 1 |
| Hollenbach, SJ; Ku, P; Lin, PH; Malinowski, J; Marlowe, CK; Scarborough, RM; Sinha, U; Wong, PW; Zhu, BY | 1 |
| Castellino, FJ; Merz, JL; Noria, F; Raymond, S; Rosen, ED; Sandoval-Cooper, M; Shulman, A; Zollman, A | 1 |
| Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H | 1 |
| Borm, A; Hirsh, J; Klement, P; Maraganore, J; Weitz, J; Wilson, G | 1 |
| Bergmann, SR; Daugherty, A; Hasapes, J; Ord, JM; Sobel, BE; Thorpe, SR | 1 |
| Loscalzo, J; Rocco, TP | 1 |
| Fischell, TA; Grant, GW; Kaplan, AV; Leung, LL; Leung, WH; McDougall, IR | 1 |
| Alderson, PO; Butler, SP; Fawwaz, RA; Kader, KL; Owen, J; Wang, TS | 1 |
| Hubbell, JA; Wagner, WR | 1 |
| Agnelli, G; Cosmi, B; Nenci, GG; Pascucci, C | 1 |
| Bass, A; Hanson, SR; Harker, LA; Kelly, AB; Krpski, WC; Marzec, UM | 1 |
| Hanson, SR; Harker, LA | 1 |
2 review(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and Thrombosis
| Article | Year |
|---|---|
Thrombin functions and antithrombotic intervention.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Antithrombins; Blood Coagulation; Cricetinae; Hirudin Therapy; Hirudins; Mice; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Rats; Receptors, Thrombin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Thrombin; Thrombosis | 1995 |
Anticoagulation: the present and future.
Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis | 2001 |
27 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and Thrombosis
| Article | Year |
|---|---|
Thrombin-targeted liposomes establish a sustained localized anticlotting barrier against acute thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Humans; Liposomes; Mice; Thrombin; Thrombosis; Unilamellar Liposomes | 2013 |
Antithrombin nanoparticles inhibit stent thrombosis in ex vivo static and flow models.
Topics: Amino Acid Chloromethyl Ketones; Antithrombins; Blood Coagulation; Blood Flow Velocity; Cells, Cultured; Drug Carriers; Endothelial Cells; Fluorocarbons; Humans; Nanoparticles; Percutaneous Coronary Intervention; Prosthesis Design; Stainless Steel; Stents; Surface Properties; Thrombosis; Time Factors | 2016 |
Inhibition of Thrombin With PPACK-Nanoparticles Restores Disrupted Endothelial Barriers and Attenuates Thrombotic Risk in Experimental Atherosclerosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Apolipoproteins E; Atherosclerosis; Blood Coagulation; Capillary Permeability; Carotid Artery Injuries; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Humans; Inflammation Mediators; Magnetic Resonance Spectroscopy; Male; Mice, Knockout; Nanoparticles; Plaque, Atherosclerotic; Signal Transduction; Thrombin; Thrombosis; Time Factors | 2016 |
P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions.
Topics: Amino Acid Chloromethyl Ketones; Apyrase; Cells, Cultured; Humans; Microfluidic Analytical Techniques; Platelet Adhesiveness; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Thrombosis | 2010 |
Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis.
Topics: Acute Disease; Amino Acid Chloromethyl Ketones; Animals; Binding Sites; Fluorocarbons; Magnetic Resonance Imaging; Mice; Nanoparticles; Partial Thromboplastin Time; Serine Proteinase Inhibitors; Thrombin; Thrombosis | 2011 |
Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood.
Topics: Amino Acid Chloromethyl Ketones; Antithrombins; Blood Coagulation; Calcium Signaling; Collagen Type I; Humans; Integrin alpha2beta1; Platelet Adhesiveness; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Pulsatile Flow; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thrombosis | 2004 |
Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Antithrombins; Aspirin; Blood Coagulation; Collagen Type III; Diffusion Chambers, Culture; Drug Synergism; Eptifibatide; Factor Xa Inhibitors; Heparin; Heterocyclic Compounds; Humans; In Vitro Techniques; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Video; Peptides; Perfusion; Platelet Aggregation; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stress, Mechanical; Thiazoles; Thrombin; Thrombosis | 2003 |
Antithrombotic effects of activated protein C and protein S in a rabbit model of microarterial thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Binding Sites; Cattle; Drug Synergism; Enzyme Activation; Female; Male; Partial Thromboplastin Time; Protein C; Protein S; Rabbits; Serine Proteinase Inhibitors; Thrombin; Thrombosis | 1995 |
Dissociation of antithrombotic and thrombocytopenic effects of D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone in rabbits.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Antithrombins; Fibrinolytic Agents; Male; Molecular Sequence Data; Rabbits; Thrombocytopenia; Thrombosis | 1994 |
A comparative study of prothrombinase and thrombin inhibitors in a novel rabbit model of non-occlusive deep vein thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Bleeding Time; Blood Coagulation; Copper; Disease Models, Animal; Drug Evaluation, Preclinical; Factor V; Factor X; Factor Xa; Fibrinolytic Agents; Gossypium; Heparin; Humans; Molecular Sequence Data; Rabbits; Thrombin; Thrombolytic Therapy; Thrombosis; Vena Cava, Inferior | 1994 |
The good, the bad and the obvious: 1993 Clemson Award for Basic Research--Keynote Lecture.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Antithrombins; Awards and Prizes; Biocompatible Materials; Blood Vessel Prosthesis; Capsules; Cell Line; Dogs; Gels; Heparin; In Vitro Techniques; Materials Testing; Molecular Sequence Data; Platelet Activation; Polyvinyl Alcohol; Societies, Scientific; Thrombosis | 1993 |
The effect of antithrombin III-independent thrombin inhibitors and heparin on fibrin accretion onto fibrin-coated polyethylene.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antithrombin III; Blood Vessel Prosthesis; Fibrin; Heparin; Hirudins; Humans; In Vitro Techniques; Microscopy, Electron, Scanning; Molecular Sequence Data; Peptide Fragments; Polyethylenes; Recombinant Proteins; Surface Properties; Thrombin; Thrombosis | 1993 |
Lasting safe interruption of endarterectomy thrombosis by transiently infused antithrombin peptide D-Phe-Pro-ArgCH2Cl in baboons.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Antithrombins; Blood Platelets; Endarterectomy; Molecular Sequence Data; Papio; Thrombosis | 1993 |
The antithrombotic effect of low molecular weight synthetic thrombin inhibitors, argatroban and PPACK, on He-Ne laser-induced thrombosis in rat mesenteric microvessels.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Arginine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mesentery; Microcirculation; Pipecolic Acids; Platelet Aggregation; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombosis | 1993 |
Platelet-derived microparticles associate with fibrin during thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Biomarkers; Blood Coagulation; Blood Platelets; Calcimycin; Calcium; Collagen; Fibrin; Fibrinogen; Humans; Ionophores; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Sequence Data; Oligopeptides; P-Selectin; Perfusion; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin; Thrombosis; von Willebrand Factor | 1996 |
Expression of hirudin fusion proteins in mammalian cells: a strategy for prevention of intravascular thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Blood Coagulation; Catalytic Domain; CD4 Antigens; Cell Line; Cytoplasmic Granules; Hirudins; Histocompatibility Antigens Class I; Humans; Membrane Proteins; P-Selectin; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Fusion Proteins; Thrombin; Thrombosis; Transfection | 1998 |
Antithrombotic and hemostatic capacity of factor Xa versus thrombin inhibitors in models of venous and arteriovenous thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Antithrombins; Arteriovenous Shunt, Surgical; Bleeding Time; Disease Models, Animal; Dose-Response Relationship, Drug; Enoxaparin; Factor Xa Inhibitors; Fibrinolytic Agents; Hemostatics; Heparin; Male; Oligopeptides; Rabbits; Serine Proteinase Inhibitors; Thiazoles; Thrombin; Thrombosis; Venous Thrombosis | 2000 |
Laser-induced noninvasive vascular injury models in mice generate platelet- and coagulation-dependent thrombi.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Blood Coagulation; Blood Platelets; Blood Vessels; Disease Models, Animal; Fibrinolytic Agents; Fluorescent Dyes; Lasers; Mice; Mice, Inbred C57BL; Microscopy, Electron; Peptides, Cyclic; Platelet Aggregation Inhibitors; Rose Bengal; Sulfoxides; Thrombosis; Time Factors | 2001 |
The effect of thrombin inhibitors on tissue plasminogen activator induced thrombolysis in a rat model.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Arterial Occlusive Diseases; Disease Models, Animal; Heparin; Hirudin Therapy; Male; Molecular Sequence Data; Partial Thromboplastin Time; Peptides; Rats; Rats, Inbred Strains; Regional Blood Flow; Thrombin; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1992 |
Imaging of thrombi with tissue-type plasminogen activator rendered enzymatically inactive and conjugated to a residualizing label.
Topics: Amino Acid Chloromethyl Ketones; Animals; Dogs; Iodine Radioisotopes; Rabbits; Radionuclide Imaging; Thrombosis; Tissue Plasminogen Activator; Tyramine | 1992 |
Imaging arterial thrombi. An elusive goal.
Topics: Amino Acid Chloromethyl Ketones; Arteries; Goals; Humans; Immunologic Techniques; Thrombosis; Tissue Plasminogen Activator; Tomography, Emission-Computed, Single-Photon; Tyramine | 1992 |
Roles of thrombin and platelet membrane glycoprotein IIb/IIIa in platelet-subendothelial deposition after angioplasty in an ex vivo whole artery model.
Topics: Amino Acid Chloromethyl Ketones; Angioplasty, Balloon; Animals; Antibodies, Monoclonal; Aorta, Thoracic; Heparin; In Vitro Techniques; Indium Radioisotopes; Microscopy, Electron, Scanning; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Thrombin; Thrombosis | 1991 |
Rapid localization of indium-111-labeled inhibited recombinant tissue plasminogen activator in a rabbit thrombosis model.
Topics: Amino Acid Chloromethyl Ketones; Animals; Binding Sites; Depression, Chemical; Indium Radioisotopes; Jugular Veins; Male; Rabbits; Radionuclide Imaging; Recombinant Proteins; Thrombosis; Time Factors; Tissue Distribution; Tissue Plasminogen Activator | 1991 |
Local thrombin synthesis and fibrin formation in an in vitro thrombosis model result in platelet recruitment and thrombus stabilization on collagen in heparinized blood.
Topics: Amino Acid Chloromethyl Ketones; Antibodies; Antithrombins; Blood Platelets; Collagen; Factor X; Fibrin; Humans; Microscopy, Electron, Scanning; Models, Biological; Oligopeptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Prothrombin; Thrombin; Thrombosis | 1990 |
Effects of therapeutic doses of heparin on thrombolysis with tissue-type plasminogen activator in rabbits.
Topics: Amino Acid Chloromethyl Ketones; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa; Fibrin; Heparin; Hirudins; Rabbits; Recombinant Proteins; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1990 |
Heparin-resistant thrombus formation by endovascular stents in baboons. Interruption by a synthetic antithrombin.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Blood Platelets; Blood Vessel Prosthesis; Catheterization; Heparin; Male; Microscopy, Electron, Scanning; Papio; Polytetrafluoroethylene; Regional Blood Flow; Stents; Thrombosis | 1990 |
Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Blood Coagulation; Blood Platelets; Fibrinolysis; Male; Papio; Platelet Aggregation; Thrombosis | 1988 |