phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide has been researched along with Ache in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (48.39) | 18.2507 |
| 2000's | 9 (29.03) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Herzog, H; Koller, J; Zhang, L | 1 |
| Chen, D; Fang, Q; Li, N; Niu, J; Xiao, J; Xu, B; Xu, K; Zhang, M; Zhang, Q; Zhang, R; Zhao, G; Zhu, H | 1 |
| Li, JX; Marusich, J; Nguyen, T; Zhang, Y | 1 |
| Gibula-Tarlowska, E; Kotlinska, JH | 1 |
| Fang, Q; Li, N; Pan, JX; Tang, HH; Wang, P; Wang, R; Wang, ZL; Yu, HP; Zhang, N; Zhang, R; Zhang, T; Zheng, T | 1 |
| Miyazaki, R; Yamada, T; Yamamoto, T | 1 |
| Fang, Q; Han, ZL; Jiang, TN; Li, N; Wang, R | 1 |
| Fang, Q; Han, ZL; He, N; Li, N; Wang, R; Wang, ZL | 1 |
| Bonnard, E; Mazarguil, H; Zajac, JM | 1 |
| Holma, R; Kalso, E; Kontinen, VK; Lemberg, K; Lintunen, M; Mustonen, K; Nystedt, JM; Panula, P | 1 |
| Iadarola, MJ; Yang, HY | 1 |
| Iadarola, MJ; Tao, T; Yang, HY | 1 |
| Kalso, EA; Kontinen, VK | 1 |
| Boisserie, F; Devillers, JP; Larcher, A; Laulin, JP; Simonnet, G | 1 |
| Aarnisalo, AA; Idänpään-Heikkilä, JJ; Kalso, E; Kontinen, VK; Panula, P | 1 |
| Altier, N; Stewart, J | 1 |
| Fyhrquist, F; Kalso, E; Panula, P; Sundblom, DM; Tigerstedt, I; Wahlbeck, K | 1 |
| Roumy, M; Zajac, JM | 1 |
| Panula, P; Pertovaara, A; Wei, H | 2 |
| Francés, B; Gelot, A; Latapie, JP; Roussin, A; Zajac, JM | 1 |
| Aarnisalo, AA; Kalso, E; Karlstedt, K; Kontinen, VK; Lintunen, M; Nieminen, ML; Panula, P; States, B; Vilim, FS; Ziff, E | 1 |
| Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J; Privat, AM; Zajac, JM | 1 |
| Kalso, E; Kontinen, VK; Panula, P; Xu, M | 1 |
| Brandt, A; Kalso, E; Kontinen, VK; Nieminen, M; Panula, P; Pertovaara, A | 1 |
| Francés, B; Latapie, JP; Zajac, JM | 1 |
| Bhardwaj, DK; Gupta, S; Gupta, YK; Pasha, S | 1 |
| Austin, CP; Bomford, D; Clements, MK; Evans, J; Figueroa, D; Gould, R; Guan, XM; Jacobson, M; Jiang, Q; Liu, Q; Mallee, J; Martin, WJ; McDonald, TP; Wang, R; Williams, DL; Yu, H; Zeng, Z | 1 |
| Hammond, MV; Hunsicker, LM; Lake, JR; Malin, DH; Shaddox, RC; Yang, HY | 1 |
| Dickenson, AH; Magnuson, DS; Roques, BP; Simonnet, G; Sullivan, AF | 1 |
| Kavaliers, M | 1 |
6 review(s) available for phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide and Ache
| Article | Year |
|---|---|
The distribution of Neuropeptide FF and Neuropeptide VF in central and peripheral tissues and their role in energy homeostasis control.
Topics: Animals; Energy Metabolism; Homeostasis; Humans; Neuropeptides; Nociception; Oligopeptides; Pain | 2021 |
Crosstalk between Opioid and Anti-Opioid Systems: An Overview and Its Possible Therapeutic Significance.
Topics: Analgesics, Opioid; Cholecystokinin; Drug Tolerance; Humans; Narcotic Antagonists; Nociceptin; Oligopeptides; Opioid Peptides; Pain; Receptors, Opioid; Substance-Related Disorders | 2020 |
Modulatory roles of the NPFF system in pain mechanisms at the spinal level.
Topics: Amino Acid Sequence; Analgesia; Animals; Disease Models, Animal; Humans; Inflammation; Molecular Sequence Data; Narcotic Antagonists; Oligopeptides; Pain; Receptors, Neuropeptide; Sequence Alignment; Spinal Cord | 2006 |
Modulatory role of neuropeptide FF system in nociception and opiate analgesia.
Topics: Acid Sensing Ion Channels; Amino Acid Sequence; Analgesics, Opioid; Animals; Humans; Membrane Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Nociceptors; Oligopeptides; Pain; Receptors, Neuropeptide; Sodium Channels | 2008 |
Neuropeptide FF, pain and analgesia.
Topics: Amino Acid Sequence; Analgesia; Animals; Cattle; Humans; Mice; Molecular Sequence Data; Neuropeptides; Oligopeptides; Pain; Rats | 1998 |
Neuropeptide FF and modulation of pain.
Topics: Animals; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain | 1999 |
25 other study(ies) available for phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide and Ache
| Article | Year |
|---|---|
Spinal administration of the multi-functional opioid/neuropeptide FF agonist BN-9 produced potent antinociception without development of tolerance and opioid-induced hyperalgesia.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Drug Tolerance; Fascia; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Morphine; Oligopeptides; Pain; Rats, Wistar | 2020 |
Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development.
Topics: Analgesics, Opioid; Animals; Anxiety; Humans; Ligands; Mice; Oligopeptides; Pain; Peptidomimetics; Rats; Receptors, Neuropeptide; Small Molecule Libraries | 2020 |
Effects of neuropeptide FF and related peptides on the antinociceptive activities of VD-hemopressin(α) in naive and cannabinoid-tolerant mice.
Topics: Adamantane; Analgesics; Animals; Dipeptides; Dose-Response Relationship, Drug; Drug Tolerance; Infusions, Intraventricular; Male; Mice; Neuropeptides; Oligopeptides; Pain; Pain Measurement; Receptors, Neuropeptide | 2015 |
Intracerebroventricular administration of 26RFa produces an analgesic effect in the rat formalin test.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Anxiety Agents; Arginine; Formaldehyde; Hot Temperature; Injections, Intraventricular; Male; Narcotic Antagonists; Neuropeptide Y; Neuropeptides; Oligopeptides; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, G-Protein-Coupled; Spinal Cord | 2009 |
Central administration of neuropeptide FF and related peptides attenuate systemic morphine analgesia in mice.
Topics: Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Antagonism; Male; Mice; Mice, Inbred Strains; Morphine; Narcotic Antagonists; Neuropeptides; Oligopeptides; Pain; Receptors, Neuropeptide | 2011 |
Effects of neuropeptide FF system on CB₁ and CB₂ receptors mediated antinociception in mice.
Topics: Analgesia; Analgesics; Animals; Benzoxazines; Indoles; Male; Mice; Morpholines; Naloxone; Naphthalenes; Oligopeptides; Pain; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2012 |
Peptide nucleic acids targeted to the mouse proNPFF(A) reveal an endogenous opioid tonus.
Topics: Animals; Chromatography, High Pressure Liquid; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Oligonucleotides, Antisense; Oligopeptides; Pain; Peptide Nucleic Acids; Radioimmunoassay; Spinal Cord; Time Factors | 2002 |
Pain- and morphine-associated transcriptional regulation of neuropeptide FF and the G-protein-coupled NPFF2 receptor gene.
Topics: Animals; Brain Stem; Male; Morphine; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Spinal Cord; Transcription, Genetic | 2004 |
Differential modulation of alpha 2-adrenergic and mu-opioid spinal antinociception by neuropeptide FF.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Male; Medetomidine; Morphine; Naltrexone; Narcotic Antagonists; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Spinal Cord; Time Factors | 1995 |
Simultaneous activation of spinal antiopioid system (neuropeptide FF) and pain facilitatory circuitry by stimulation of opioid receptors in rats.
Topics: Animals; Heroin; In Vitro Techniques; Male; Morphine; Naloxone; Narcotic Antagonists; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Spinal Cord; Tetrodotoxin | 1995 |
Neuropeptide FF in the rat spinal cord during carrageenan inflammation.
Topics: Animals; Carrageenan; Hot Temperature; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Neurons; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 1997 |
Neuropeptide FF in the VTA blocks the analgesic effects of both intra-VTA morphine and exposure to stress.
Topics: Analgesics, Opioid; Animals; Male; Morphine; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Rats; Rats, Wistar; Stress, Physiological; Ventral Tegmental Area | 1997 |
Neuropeptide FF-like immunoreactivity in human cerebrospinal fluid of chronic pain patients and healthy controls.
Topics: Adult; Aged; Brain; Case-Control Studies; Chronic Disease; Female; Humans; Immunochemistry; Male; Middle Aged; Neuropeptides; Oligopeptides; Pain | 1997 |
A differential modulation of allodynia, hyperalgesia and nociception by neuropeptide FF in the periaqueductal gray of neuropathic rats: interactions with morphine and naloxone.
Topics: Animals; Drug Interactions; Hindlimb; Hyperalgesia; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Neuralgia; Oligopeptides; Pain; Periaqueductal Gray; Rats; Rats, Wistar; Skin; Spinal Nerves; Touch | 1998 |
Anti-opioid efficacy of neuropeptide FF in morphine-tolerant mice.
Topics: Animals; Antibodies; Drug Tolerance; Hot Temperature; Male; Mice; Morphine; Morphine Dependence; Narcotic Antagonists; Narcotics; Neuropeptides; Nociceptors; Olfactory Bulb; Oligopeptides; Pain; Pain Measurement; Receptors, Neuropeptide; Reflex; Spinal Cord | 1998 |
Gene for pain modulatory neuropeptide NPFF: induction in spinal cord by noxious stimuli.
Topics: Amino Acid Sequence; Animals; Brain Stem; Cattle; Ganglia, Spinal; Humans; Mice; Molecular Sequence Data; Oligopeptides; Pain; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Spinal Cord | 1999 |
Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine-induced analgesia in mononeuropathic and diabetic rats.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hyperalgesia; Injections, Spinal; Male; Morphine; Naltrexone; Narcotic Antagonists; Nervous System Diseases; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Somatostatin; Time Factors; Vocalization, Animal | 1999 |
Effects of (1DMe)NPYF, a synthetic neuropeptide FF analogue, in different pain models.
Topics: Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Drug Antagonism; Injections, Spinal; Male; Motor Activity; Naloxone; Oligopeptides; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley | 1999 |
Opposing interplay between Neuropeptide FF and nitric oxide in antinociception and hypothermia.
Topics: Analgesics, Opioid; Animals; Area Under Curve; Arginine; Body Temperature; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Hypothermia; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pain; Temperature | 2000 |
Modulation of pain by [1DMe]NPYF, a stable analogue of neuropeptide FF, in neuropathic rats.
Topics: Animals; Behavior, Animal; Chronic Disease; Electric Stimulation; H-Reflex; Hot Temperature; Hyperalgesia; Injections, Spinal; Nervous System Diseases; Neurons; Nociceptors; Oligopeptides; Pain; Periaqueductal Gray; Rats; Reference Values; Spinal Cord; Touch | 2001 |
Effects of intracerebroventricularly administered chimeric peptide of metenkephalin and FMRFa--[D-Ala2]YFa-on antinociception and its modulation in mice.
Topics: Analgesics, Opioid; Animals; Brain; Drug Interactions; Enkephalin, Methionine; FMRFamide; Injections, Intraventricular; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Neurons; Nociceptors; Oligopeptides; Pain; Pain Measurement; Recombinant Fusion Proteins | 2001 |
Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception.
Topics: Amino Acid Sequence; Analgesics; Analgesics, Opioid; Animals; Cells, Cultured; Central Nervous System; CHO Cells; Cricetinae; Disease Models, Animal; Drug Interactions; Humans; Male; Mice; Molecular Sequence Data; Morphine; Oligopeptides; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sequence Homology, Amino Acid | 2001 |
IgG from neuropeptide FF antiserum reverses morphine tolerance in the rat.
Topics: Amino Acid Sequence; Analgesia; Animals; Cross Reactions; Drug Tolerance; FMRFamide; Immunoglobulin G; Male; Molecular Sequence Data; Morphine; Neuropeptides; Oligopeptides; Pain; Rabbits; Rats; Rats, Inbred Strains | 1991 |
Differential interactions of cholecystokinin and FLFQPQRF-NH2 with mu and delta opioid antinociception in the rat spinal cord.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Injections, Spinal; Male; Nerve Fibers; Neurons; Oligopeptides; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide; Spinal Cord | 1990 |
Inhibitory influences of mammalian FMRFamide (Phe-Met-Arg-Phe-amide)-related peptides on nociception and morphine- and stress-induced analgesia in mice.
Topics: Amino Acid Sequence; Analgesia; Animals; Circadian Rhythm; Endorphins; FMRFamide; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Morphine; Neuropeptides; Oligopeptides; Pain; Restraint, Physical; Stress, Psychological | 1990 |