phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide has been researched along with Pain in 26 studies
phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide: cyclic somatostatin octapeptide analog with high affinity & selectivity toward mu opioid receptors
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pain was induced by formalin injection into the hindpaw." | 1.37 | Synergistic interaction between intrathecal ginsenosides and morphine on formalin-induced nociception in rats. ( Choi, JI; Kim, CM; Kim, KS; Kim, WM; Kim, YO; Lee, HG; Yoon, MH, 2011) |
| "To determine whether 1DMe could correct hyperalgesia and restore morphine efficacy in mononeuropathic (MN) and diabetic (D) rats we examined the spinal effect of 1DMe in MN and D rats without and after spinal blockade of mu- and delta-opioid receptors with CTOP and naltrindole, respectively." | 1.30 | Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine-induced analgesia in mononeuropathic and diabetic rats. ( Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J; Privat, AM; Zajac, JM, 1999) |
| " Diazoxide (2 microg/mouse) shifted morphine's dose-response curve 47-fold, while levcromakalim (0." | 1.30 | ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides. ( Lohmann, AB; Welch, SP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Godoi, MM | 1 |
| Junior, HZ | 1 |
| da Cunha, JM | 1 |
| Zanoveli, JM | 1 |
| Tobaldini, G | 1 |
| Sardi, NF | 1 |
| Guilhen, VA | 1 |
| Fischer, L | 2 |
| Nizhnikov, ME | 1 |
| Kozlov, AP | 1 |
| Kramskaya, TA | 1 |
| Varlinskaya, EI | 1 |
| Spear, NE | 1 |
| Mizoguchi, H | 2 |
| Takagi, H | 1 |
| Watanabe, C | 2 |
| Yonezawa, A | 1 |
| Sato, T | 1 |
| Sakurada, T | 2 |
| Sakurada, S | 2 |
| Tortorici, V | 1 |
| Aponte, Y | 1 |
| Acevedo, H | 1 |
| Nogueira, L | 1 |
| Vanegas, H | 1 |
| Galeotti, N | 1 |
| Vivoli, E | 1 |
| Bilia, AR | 1 |
| Bergonzi, MC | 1 |
| Bartolini, A | 1 |
| Ghelardini, C | 1 |
| Pozza, DH | 1 |
| Potes, CS | 1 |
| Barroso, PA | 1 |
| Azevedo, L | 1 |
| Castro-Lopes, JM | 1 |
| Neto, FL | 1 |
| Gear, RW | 1 |
| Levine, JD | 1 |
| Yoon, MH | 1 |
| Kim, KS | 1 |
| Lee, HG | 1 |
| Kim, CM | 1 |
| Kim, WM | 1 |
| Choi, JI | 1 |
| Kim, YO | 1 |
| Tambeli, CH | 1 |
| Monaliza, SL | 1 |
| Menescal-de-Oliveira, L | 1 |
| Parada, CA | 1 |
| Wu, HE | 1 |
| Sun, HS | 1 |
| Darpolar, M | 1 |
| Dunn, W | 1 |
| Tseng, LF | 1 |
| Narita, M | 1 |
| Kaneko, C | 1 |
| Miyoshi, K | 1 |
| Nagumo, Y | 1 |
| Kuzumaki, N | 1 |
| Nakajima, M | 1 |
| Nanjo, K | 1 |
| Matsuzawa, K | 1 |
| Yamazaki, M | 1 |
| Suzuki, T | 1 |
| Nakayama, D | 1 |
| Watanabe, H | 1 |
| Abul-Husn, NS | 1 |
| Sutak, M | 1 |
| Milne, B | 1 |
| Jhamandas, K | 1 |
| Han, SR | 1 |
| Lee, MK | 1 |
| Lim, KH | 1 |
| Yang, GY | 1 |
| Jeon, HJ | 1 |
| Ju, JS | 1 |
| Yoon, YW | 1 |
| Kim, SK | 1 |
| Ahn, DK | 1 |
| Spanagel, R | 1 |
| Almeida, OF | 1 |
| Shippenberg, TS | 1 |
| Schäfer, M | 1 |
| Carter, L | 1 |
| Stein, C | 1 |
| Roychowdhury, SM | 1 |
| Fields, HL | 2 |
| Budai, D | 1 |
| Hao, JX | 1 |
| Yu, W | 1 |
| Xu, XJ | 1 |
| Courteix, C | 1 |
| Coudoré-Civiale, MA | 1 |
| Privat, AM | 1 |
| Zajac, JM | 1 |
| Eschalier, A | 1 |
| Fialip, J | 1 |
| Lohmann, AB | 1 |
| Welch, SP | 1 |
| Spreekmeester, E | 1 |
| Rochford, J | 1 |
| Watkins, LR | 1 |
| Wiertelak, EP | 1 |
| Maier, SF | 1 |
| Fanselow, MS | 1 |
| Calcagnetti, DJ | 1 |
| Helmstetter, FJ | 1 |
| Gulya, K | 1 |
| Kriván, M | 1 |
| Nyolczas, N | 1 |
| Sarnyai, Z | 1 |
| Kovács, GL | 1 |
26 other studies available for phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and Pain
| Article | Year |
|---|---|
Mu-opioid and CB1 cannabinoid receptors of the dorsal periaqueductal gray interplay in the regulation of fear response, but not antinociception.
Topics: Analgesics, Opioid; Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Agonists; Can | 2020 |
Pain Inhibits Pain: an Ascending-Descending Pain Modulation Pathway Linking Mesolimbic and Classical Descending Mechanisms.
Topics: Analgesia; Analgesics, Opioid; Animals; Benzazepines; Lidocaine; Male; Medulla Oblongata; Pain; Pain | 2019 |
Central effects of ethanol interact with endogenous mu-opioid activity to control isolation-induced analgesia in maternally separated infant rats.
Topics: Animals; Central Nervous System Depressants; Drinking Behavior; Drinking Water; Ethanol; Female; Gro | 2014 |
Involvement of multiple µ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission.
Topics: Analgesics; Animals; Capsaicin; Male; Mice; N-Methylaspartate; Nociception; Oligopeptides; Pain; Pre | 2014 |
Tolerance to non-opioid analgesics in PAG involves unresponsiveness of medullary pain-modulating neurons in male rats.
Topics: Action Potentials; Analgesics, Non-Narcotic; Animals; Aspirin; Dipyrone; Drug Tolerance; Male; Medul | 2009 |
A prolonged protein kinase C-mediated, opioid-related antinociceptive effect of st John's Wort in mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liq | 2010 |
Nociceptive behaviour upon modulation of mu-opioid receptors in the ventrobasal complex of the thalamus of rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Ankle; Behavior, Animal; Disease Models, Animal; | 2010 |
Nucleus accumbens facilitates nociception.
Topics: Analysis of Variance; Animals; Electrodes, Implanted; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injection | 2011 |
Synergistic interaction between intrathecal ginsenosides and morphine on formalin-induced nociception in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, | 2011 |
The functional role of ascending nociceptive control in defensive behavior.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Immobility Response, Tonic; Male; Mo | 2012 |
Antinociceptive properties of oxymorphazole in the mouse.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Spin | 2003 |
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala.
Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzamides; | 2006 |
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkeph | 2007 |
Augmentation of spinal morphine analgesia and inhibition of tolerance by low doses of mu- and delta-opioid receptor antagonists.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; In | 2007 |
Intramuscular administration of morphine reduces mustard-oil-induced craniofacial-muscle pain behavior in lightly anesthetized rats.
Topics: Analgesics; Anesthesia, General; Animals; Inflammation; Injections; Injections, Intramuscular; Male; | 2008 |
Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes.
Topics: Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Drug Interactions; Enkephalin, Ala(2)-M | 1994 |
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue.
Topics: Analysis of Variance; Animals; Antibodies; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclospo | 1994 |
Endogenous opioids acting at a medullary mu-opioid receptor contribute to the behavioral antinociception produced by GABA antagonism in the midbrain periaqueductal gray.
Topics: Animals; Bicuculline; Brain Mapping; GABA Antagonists; Male; Medulla Oblongata; Mesencephalon; Micro | 1996 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-M | 1998 |
Evidence that spinal endogenous opioidergic systems control the expression of chronic pain-related behaviors in spinally injured rats.
Topics: Animals; Behavior, Animal; Chronic Disease; Cold Temperature; Female; Hyperalgesia; Injections, Spin | 1998 |
Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine-induced analgesia in mononeuropathic and diabetic rats.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Diabetes Mellitus, Experimenta | 1999 |
ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine | 1999 |
Selective mu and delta, but not kappa, opiate receptor antagonists inhibit the habituation of novelty-induced hypoalgesia in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Male; Naltrexone; Narcoti | 2000 |
Kappa opiate receptors mediate tail-shock induced antinociception at spinal levels.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electroshock; Indoles; Injections, | 1992 |
Role of mu and kappa opioid receptors in conditional fear-induced analgesia: the antagonistic actions of nor-binaltorphimine and the cyclic somatostatin octapeptide, Cys2Tyr3Orn5Pen7-amide.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; B | 1989 |
Central effects of the potent and highly selective mu opioid antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) in mice.
Topics: Animals; Body Temperature; Body Weight; Brain; Drug Tolerance; Injections, Intraventricular; Male; M | 1988 |