phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide has been researched along with Allodynia in 15 studies
phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide: cyclic somatostatin octapeptide analog with high affinity & selectivity toward mu opioid receptors
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using an established rat model of paclitaxel-induced peripheral neuropathy, we evaluated the effect of electroacupuncture (EA) on paclitaxel-induced hyperalgesia and allodynia that has not been studied in an animal model." | 7.77 | The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy. ( Berman, BM; Lao, L; Li, A; Meng, X; Ren, K; Tan, M; Xin, J; Zhang, RX; Zhang, Y, 2011) |
| " Using an established rat model of paclitaxel-induced peripheral neuropathy, we evaluated the effect of electroacupuncture (EA) on paclitaxel-induced hyperalgesia and allodynia that has not been studied in an animal model." | 3.77 | The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy. ( Berman, BM; Lao, L; Li, A; Meng, X; Ren, K; Tan, M; Xin, J; Zhang, RX; Zhang, Y, 2011) |
| "We tested the hypothesis that chronic pain development (pain chronification) and ongoing chronic pain (chronic pain) reduce the activity and induce plastic changes in an endogenous analgesia circuit, the ascending nociceptive control." | 1.42 | Effect of pain chronification and chronic pain on an endogenous pain modulation circuit in rats. ( Athie, M; Dias, EV; Lamana, SM; Miranda, J; Parada, CA; Tambeli, CH, 2015) |
| "This also reversed hyperalgesia in behaving animals." | 1.38 | Erasure of a spinal memory trace of pain by a brief, high-dose opioid administration. ( Benrath, J; Drdla-Schutting, R; Sandkühler, J; Wunderbaldinger, G, 2012) |
| "Our experiments show that acute thermal hyperalgesia is blocked in periaqueductal gray with the microOR antagonist CTOP, the NMDA antagonist MK801 and the protein kinase C inhibitor chelerythrine." | 1.35 | Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception. ( Bianchi, E; Galeotti, N; Ghelardini, C; Guarna, M; Norcini, M; Stefano, GB; Vivoli, E; Zhu, W, 2008) |
| "However, OFQ dose-dependently produced hyperalgesia in rats pretreated with naloxone, implying that OFQ can indeed produce hyperalgesia once an endogenous opioidergic tone is inhibited." | 1.31 | Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test. ( Lutfy, K; Maidment, NT, 2000) |
| "To determine whether 1DMe could correct hyperalgesia and restore morphine efficacy in mononeuropathic (MN) and diabetic (D) rats we examined the spinal effect of 1DMe in MN and D rats without and after spinal blockade of mu- and delta-opioid receptors with CTOP and naltrindole, respectively." | 1.30 | Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine-induced analgesia in mononeuropathic and diabetic rats. ( Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J; Privat, AM; Zajac, JM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gonçalves Dos Santos, G | 1 |
| Vieira, WF | 1 |
| Vendramini, PH | 1 |
| Bassani da Silva, B | 1 |
| Fernandes Magalhães, S | 1 |
| Tambeli, CH | 2 |
| Parada, CA | 2 |
| Custodio-Patsey, L | 1 |
| Donahue, RR | 1 |
| Fu, W | 1 |
| Lambert, J | 1 |
| Smith, BN | 1 |
| Taylor, BK | 1 |
| Kwok, CHT | 1 |
| Devonshire, IM | 1 |
| Bennett, AJ | 1 |
| Hathway, GJ | 1 |
| Miranda, J | 1 |
| Lamana, SM | 1 |
| Dias, EV | 1 |
| Athie, M | 1 |
| Bianchi, E | 2 |
| Norcini, M | 2 |
| Smrcka, A | 1 |
| Ghelardini, C | 2 |
| Zhang, Y | 2 |
| Meng, X | 2 |
| Li, A | 2 |
| Xin, J | 2 |
| Berman, BM | 2 |
| Lao, L | 2 |
| Tan, M | 2 |
| Ren, K | 2 |
| Zhang, RX | 2 |
| Heinl, C | 1 |
| Drdla-Schutting, R | 2 |
| Xanthos, DN | 1 |
| Sandkühler, J | 2 |
| Benrath, J | 1 |
| Wunderbaldinger, G | 1 |
| Back, SK | 1 |
| Lee, J | 1 |
| Hong, SK | 1 |
| Na, HS | 1 |
| Galeotti, N | 1 |
| Vivoli, E | 1 |
| Zhu, W | 1 |
| Stefano, GB | 1 |
| Guarna, M | 1 |
| Gendron, L | 1 |
| Pintar, JE | 1 |
| Chavkin, C | 1 |
| Hao, JX | 1 |
| Yu, W | 1 |
| Xu, XJ | 1 |
| Courteix, C | 1 |
| Coudoré-Civiale, MA | 1 |
| Privat, AM | 1 |
| Zajac, JM | 1 |
| Eschalier, A | 1 |
| Fialip, J | 1 |
| Lutfy, K | 1 |
| Maidment, NT | 1 |
15 other studies available for phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and Allodynia
| Article | Year |
|---|---|
Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Carrageenan; Dipyrone; Hydrolysis; Hyperalges | 2020 |
Sex differences in kappa opioid receptor inhibition of latent postoperative pain sensitization in dorsal horn.
Topics: Animals; Benzamides; Extracellular Signal-Regulated MAP Kinases; Female; Hyperalgesia; Male; Mice, I | 2020 |
Postnatal maturation of endogenous opioid systems within the periaqueductal grey and spinal dorsal horn of the rat.
Topics: Age Factors; Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Enkephalin, Ala(2) | 2014 |
Effect of pain chronification and chronic pain on an endogenous pain modulation circuit in rats.
Topics: Analgesics; Animals; Capsaicin; Chronic Pain; Dinoprostone; Hyperalgesia; Male; Nociception; Nucleus | 2015 |
Supraspinal Gbetagamma-dependent stimulation of PLCbeta originating from G inhibitory protein-mu opioid receptor-coupling is necessary for morphine induced acute hyperalgesia.
Topics: Animals; Cyclohexanes; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Explor | 2009 |
Acupuncture alleviates the affective dimension of pain in a rat model of inflammatory hyperalgesia.
Topics: Affect; Animals; Avoidance Learning; Conditioning, Classical; Disease Models, Animal; Electroacupunc | 2011 |
The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electroacu | 2011 |
Distinct mechanisms underlying pronociceptive effects of opioids.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Rela | 2011 |
Erasure of a spinal memory trace of pain by a brief, high-dose opioid administration.
Topics: Analgesics, Opioid; Animals; Calcium Signaling; Evoked Potentials; Hyperalgesia; Long-Term Potentiat | 2012 |
Loss of spinal mu-opioid receptor is associated with mechanical allodynia in a rat model of peripheral neuropathy.
Topics: Amino Acid Sequence; Animals; Axotomy; Disease Models, Animal; Hyperalgesia; Injections, Intraperito | 2006 |
Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception.
Topics: Alkaloids; Analysis of Variance; Animals; Behavior, Animal; Benzophenanthridines; Dizocilpine Maleat | 2008 |
Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia.
Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Freund's Adjuvan | 2007 |
Evidence that spinal endogenous opioidergic systems control the expression of chronic pain-related behaviors in spinally injured rats.
Topics: Animals; Behavior, Animal; Chronic Disease; Cold Temperature; Female; Hyperalgesia; Injections, Spin | 1998 |
Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine-induced analgesia in mononeuropathic and diabetic rats.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Diabetes Mellitus, Experimenta | 1999 |
Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Injections, Intrav | 2000 |