phenylalanine-arginine-beta-naphthylamide and Acinetobacter-Infections

phenylalanine-arginine-beta-naphthylamide has been researched along with Acinetobacter-Infections* in 3 studies

Reviews

1 review(s) available for phenylalanine-arginine-beta-naphthylamide and Acinetobacter-Infections

ArticleYear
Treatment of multiresistant Acinetobacter baumannii infections.
    Current opinion in investigational drugs (London, England : 2000), 2009, Volume: 10, Issue:2

    Acinetobacter baumannii are non-fermentative, Gram-negative bacilli that cause a large number of nosocomial infections worldwide. They are characterized by frequent multiresistance due to multiple mechanisms. As a consequence, infections caused by strains exhibiting resistance to carbapenems and, sometimes, polymyxins, are regularly observed. Sulbactam, colistin and combinations of different antimicrobials have been reported as new therapeutic approaches for infections caused by resistant A baumannii strains. This review focuses on current and potential new drugs, such as rifampin, tigecycline, antimicrobial peptides, efflux pump resistant and inhibitor drugs, and enzyme inhibitors.

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Clinical Trials as Topic; Dipeptides; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Humans; Minocycline; Molecular Structure; Rifampin; Tigecycline

2009

Other Studies

2 other study(ies) available for phenylalanine-arginine-beta-naphthylamide and Acinetobacter-Infections

ArticleYear
Biofilm formation in Acinetobacter baumannii was inhibited by PAβN while it had no association with antibiotic resistance.
    MicrobiologyOpen, 2020, Volume: 9, Issue:9

    This study was conducted to investigate the relationship between Acinetobacter baumannii biofilm formation and antibiotic resistance. Furthermore, the effects of PAβN, a potential efflux pump inhibitor, on A. baumannii biofilm formation and dispersion were tested, and the gene expression levels of efflux pumps were determined to study the mechanisms. A total of 92 A. baumannii isolates from infected patients were collected and identified by multiplex PCR. The antimicrobial susceptibility of A. baumannii clinical isolates was tested by VITEK 2 COMPACT

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Dipeptides; Drug Resistance, Bacterial; Gene Expression; Genotype; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Polymerase Chain Reaction

2020
Expression of the adeB gene and responsiveness to 1-(1-naphthylmethyl)-piperazine and phenylalanyl-arginyl-β-naphthylamide in clinical isolates of Acinetobacter baumannii.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:5

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; Dipeptides; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Piperazines

2013