phenylalanine has been researched along with Pregnancy in 622 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 378 (60.77) | 18.7374 |
| 1990's | 88 (14.15) | 18.2507 |
| 2000's | 74 (11.90) | 29.6817 |
| 2010's | 50 (8.04) | 24.3611 |
| 2020's | 32 (5.14) | 2.80 |
| Authors | Studies |
|---|---|
| Ascherl, RG; Baerwald, C; Beblo, S; Heller, C; Joerg-Streller, M; Joos, O; Jung, A; Lier, D; Luttat, S; Matzgen, S; Och, U; Rohde, C; Rosenbaum-Fabian, S; Schönherr, K; Thiele, AG; Winkler, T | 1 |
| Stoev, SD | 1 |
| Kim, J; Kim, KH; Kim, SK; Ko, JM; Lee, J; Lee, JY; Lee, S; Mook-Jung, I; Park, JC; Park, SH | 1 |
| Çoker, M; Coşkun, T; Mungan, NÖ; Özel, HG; Sivri, HS | 1 |
| Ji, X; Jiang, P; Li, Y; Yan, W; Yue, H | 1 |
| Martel, F; Rodrigues, H; Silva, C | 1 |
| Baerwald, CGO; Beblo, S; Burgard, P; Das, A; Dokoupil, K; Fleissner, S; Freisinger, P; Garbade, SF; Gleich, F; Grohmann-Held, K; Heddrich-Ellerbrok, M; Jung, A; Kölker, S; Korpel, V; Krämer, J; Lier, D; Maier, EM; Meyer, U; Mühlhausen, C; Mütze, U; Newger, M; Och, U; Plöckinger, U; Rosenbaum-Fabian, S; Rutsch, F; Santer, R; Schick, P; Schwarz, M; Spiekerkötter, U; Strittmatter, U; Thiele, AG; Vom Dahl, S; Ziagaki, A | 1 |
| Gao, LM; Liu, GY; Wang, HL; Wassie, T; Wu, X; Yin, YL | 1 |
| Alvarez, JA; Cui, X; Ramakrishnan, U; Schoen, MS; Singh, RH; Ziegler, TR | 1 |
| Ahring, K; Jørgensen, C; Lund, AM; Nielsen, MR; Ørngreen, MC | 1 |
| Huang, Y; Kong, Y; Li, B; Loor, JJ; Mei, L; Qi, S; Shen, B; Tan, P; Wang, J; Wei, B; Zhang, Z; Zhao, C; Zhu, X | 1 |
| Longo, N; Rovelli, V | 1 |
| Bhattacharya, A; Chakraborty, P; Chaudhury, K; Dasgupta, S; Joshi, M; Mitra, I; Ray, CD; Sherpa, DD; Subramani, E | 1 |
| Canton, M; Feillet, F; Jeannesson, E; Namour, F; Oussalah, A; Theron, M; Wiedemann, A | 1 |
| Fang, Z; Hu, G; Huo, X; Leng, J; Li, J; Li, N; Li, W; Liu, J; Wang, H; Yang, K; Yang, X; Yu, Z | 1 |
| Adams, AD; Demarest, OM; Fiesco-Roa, MÓ; Hobert, JA; Jenkins, GP; Malinowski, J; Rothberg, PG; Wong, L | 1 |
| Angeloni, A; Carducci, C; De Leo, S; Leuzzi, V; Manti, F; Nardecchia, F; Palermo, L; Romani, C | 1 |
| Cai, Y; Deng, Z; Hao, H; Li, S; Shi, C; Song, J; Yang, Q; Zhuang, G | 1 |
| Alptekin, IM; Barta, AG; Burlina, AB; Burlina, AP; Carretta, J; Cazzorla, C; Everts, R; Hermida-Ameijeiras, Á; Hochuli, M; Maissen-Abgottspon, S; Muri, R; Reismann, P; Trepp, R | 1 |
| Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA | 1 |
| Ball, RO; Courtney-Martin, G; Elango, R; Ennis, MA; Lim, K; Pencharz, PB; Rasmussen, BF | 1 |
| Agustí, N; Cobo, T; Gratacós, E; Palacio, M; Pineda-Lucena, A; Puchades-Carrasco, L; Sánchez-García, AB; Vicente-Muñoz, S | 1 |
| Chen, Z; Han, B; He, C; Hui, Q; Li, X; Shen, M; Wang, K; Wang, L; Ye, F; Zou, H | 1 |
| Bennato, F; Franceschini, N; Grotta, L; Ianni, A; Martino, C; Martino, G | 1 |
| Baronio, F; Bettocchi, I; Brodosi, L; Caletti, MT; Cassio, A; Cataldi, S; Marchesini, G; Petroni, ML | 1 |
| Chyż, K; Hozyasz, KK; Żółkowska, J | 1 |
| Arnold, GL; DeLuca, J; Lowe, TB | 1 |
| Ball, RO; Courtney-Martin, G; Elango, R; Ennis, MA; Lim, K; Ong, AJ; Pencharz, PB | 1 |
| Endo, F; Ida, H; Ito, T; Kure, S; Matsubara, Y; Matuo, M; Nakamura, K; Ohura, T; Okano, Y; Okuyama, T; Owada, M; Shintaku, H; Takayanagi, M; Yoshino, M | 1 |
| Chikada, S; Kakurai, Y; Seki, S; Tamura, M; Wada, K | 1 |
| Bain, JR; Ilkayeva, OR; Lowe, LP; Lowe, WL; Metzger, BE; Muehlbauer, MJ; Newgard, CB; Nodzenski, M; Reisetter, AC; Scholtens, DM; Stevens, RD | 1 |
| Celik, H; Kaplan, DS; Kumru, B; Oztürk Hismi, B | 1 |
| Ball, RO; Elango, R; Lim, K; Payne, M; Pencharz, PB; Stephens, T | 1 |
| Biondi, R; Bottiglieri, L; Brancorsini, S; Brillo, E; Capodicasa, E; Cretoiu, D; Egidi, MG; Gerli, S; Micu, R; Poli, G; Renzo, GCD; Suciu, N | 1 |
| Arai-Ichinoi, N; Kure, S; Murayama, K; Sakamoto, O | 1 |
| Bragança, LF; Corrêa, MN; Del Pino, FAB; Feijó, JO; Kegles, F; Londero, US; Madruga, OC; Marins, L; Schmitt, E; Schmoeller, E | 1 |
| Seagraves, NJ; Watson, JN | 1 |
| Bartholomew, D; McBride, KL; Pluciniczak, J; Rhyand, T | 1 |
| Lichter-Konecki, U; Vockley, J | 1 |
| Körmöczi, GF; Macher, S; Matzhold, EM; Polin, H; Schönbacher, M; Wagner, T | 1 |
| Guo, J; Guo, Y; Jiang, H; Sa, Y; Song, J; Sun, Z; Wang, T; Wang, X; Xu, K; Yang, Y; Yuan, L | 1 |
| Hu, J; Peng, J; Shen, A; Yang, J; Yin, T; Zhao, Q; Zou, Y | 1 |
| Hamosh, A; Hoover-Fong, J; Koerner, C; Martino, T; Yenokyan, G | 1 |
| Bókay, J; Kiss, E; Simon, E; Szőnyi, L | 1 |
| Arning, E; Azen, C; Bottiglieri, T; Moseley, K; Yano, S | 1 |
| Kassel, R; Rudnick, DA; Sprietsma, L | 1 |
| Banta-Wright, SA; Houck, GM; Knafl, KA; Press, N; Steiner, RD | 1 |
| Acosta, PB; Cunningham, A; Frazier, D; Huntington, K; Mofidi, S; Moseley, K; Ogata, B; Rohr, F; Singh, RH; Splett, PL; Van Calcar, SC; Vockley, J | 1 |
| Li, DZ; Li, R; Wang, T; Xie, XM | 1 |
| Burton, BK; Cohen-Pfeffer, JL; Fong, CT; Grange, DK; Hillman, RE; Hunt, J; Mahoney, JJ; Vockley, J; Yano, S | 1 |
| Bilic, J; Blaschitz, A; Desoye, G; Gauster, M; Huppertz, B; Kremshofer, J; Siwetz, M | 1 |
| Debray, FG; Feillet, F; Fofou-Caillierez, MB; Lotz-Havla, AS; Muntau, AC; Puchwein-Schwepcke, A; Trefz, FF; van Spronsen, F | 1 |
| Bai, Y; Cao, J; Chen, Y; Dong, Y; Liu, G; Wang, Z; Yang, H | 1 |
| Böhles, H; Buxmann, H; Eggermann, T; Lorenz, D; Merz, E; Schlößer, RL; Sewell, AC | 1 |
| Bortoluzzi, VT; de Franceschi, ID; Rieger, E; Wannmacher, CM | 1 |
| Antoniolli, AC; Cantero, WB; Fronza, LS; Mauro, MO; Oliveira, RJ; Pesarini, JR; Sena, MC; Victorelli, SG | 1 |
| Ball, RO; Franco, DJ; Josephson, JK; Moehn, S; Pencharz, PB | 1 |
| Ball, RO; Elango, R; Payne, M; Pencharz, PB; Stephens, TV | 1 |
| Murphy, E | 1 |
| Bélanger-Quintana, A; Blau, N; Burlina, A; Cleary, M; Coşkun, T; Feillet, F; Giżewska, M; MacDonald, A; Muntau, AC; Trefz, FK; van Spronsen, FJ | 1 |
| Ahring, K; Almeida, MF; Belanger-Quintana, A; Blau, N; Burlina, A; Cleary, M; Coskum, T; Dokoupil, K; Evans, S; Feillet, F; Giżewska, M; Gokmen Ozel, H; Kamieńska, E; Lammardo, AM; Lotz-Havla, AS; MacDonald, A; Maillot, F; Muntau, AC; Puchwein-Schwepcke, A; Robert, M; Rocha, JC; Santra, S; Skeath, R; Strączek, K; Trefz, FK; van Dam, E; van Rijn, M; van Spronsen, F; Vijay, S | 1 |
| Brooks, S; Crocker, IP; Glazier, JD; Johnstone, ED; Lewis, RM; Lofthouse, EM; Panitchob, N; Perazzolo, S; Sengers, BG; Sibley, CP; Widdows, KL | 1 |
| Bereczky, Z; Boda, Z; Gindele, R; Ilonczai, P; Kovács, B; Marján, E; Muszbek, L; Oláh, Z; Pfliegler, G; Selmeczi, A; Speker, M; Udvari, Á | 1 |
| Xiao, YX; Yang, WX | 1 |
| Cunningham, AC; Douglas, TD; Frazier, DM; Hook, DG; Jeffers, L; McCune, H; Mofidi, S; Moseley, KD; Ogata, B; Pendyal, S; Rohr, F; Singh, RH; Skrabal, J; Splett, PL; Stembridge, A; Wessel, A | 1 |
| de Parscau, L; Teissier, R | 1 |
| Baudin, J; Lee, PJ; Lilburn, M; Maillot, F; Morley, DW | 1 |
| Durham-Shearer, SJ; Judd, PA; Thomas, JE; Whelan, K | 1 |
| Antsaklis, A; Karikas, GA; Papakonstantinou, ED; Papassotiriou, I; Schulpis, KH; Tsakiris, S; Vlachos, DG; Vlachos, GD | 1 |
| Dorst, KY; Duvekot, JJ; Schierbeek, H; Schoonderwaldt, EM; Steegers, EA; van den Akker, CH; van Goudoever, JB; Vermes, A | 1 |
| Ellerbrok, M; Kohlschütter, B; Merkel, M; Santer, R; Tchirikov, M; Ullrich, K; Zschocke, J | 1 |
| Lehnen, H; Pascheberg, U; Schwennicke, C; Vinke, M | 1 |
| Didycz, B; Lemańska, D; Słuszniak, A | 1 |
| Bouchlariotou, S; Maroulis, G; Tsikouras, P | 1 |
| Jamroz, E; Marszał, E; Paprocka, J; Wiktor, M | 1 |
| Baerwald, CG; Stepan, H; Unger, S; Weigel, JF | 1 |
| Van den Akker, CH; Van Goudoever, JB | 1 |
| Harada, N; Ohira, T; Watanabe, Y; Yoshino, M | 1 |
| Akar, M; Altug, N; Dilmen, U; Erdeve, O; Gokmen, T; Oguz, SS | 1 |
| Domoto, T; Nakano, H; Nakanuma, Y; Sakr, MA; Sasaki, M; Sato, H; Takino, T; Wong, RW | 1 |
| Cao, KW; Chen, XF; Chu, QC; Li, WL; Tang, WR; Ye, JN; Zhang, DL; Zhang, JB | 1 |
| Carpenter, RH; Chan, H; Dawson, C; Ellerton, C; Lachmann, RH; Maritz, C; Murphy, E | 1 |
| Chauhan, D; Macdonald, A; Nanuwa, K; Nathan, M; Parkes, L | 1 |
| Bassell, GJ; Welshhans, K | 1 |
| Cahill, AG; Dietzen, DJ; Goetzinger, KR; Macones, GA; Nelson, DM; Odibo, AO; Odibo, L | 1 |
| Cobo, ER; Corbeil, LB; Reed, SL | 1 |
| Duvekot, JJ; Hop, WC; Prick, BW | 1 |
| Brucker-Davis, F; Déchaux, H; Fénichel, P; Ferrari, P; Gal, J; Harthe, C; Pacini, P; Pugeat, M; Wagner-Mahler, K | 1 |
| Assoun, M; Cano, A; de Parscau, L; Feillet, F; Fouilhoux, A; Mention, K; Nowak, E; Oger, E; Ogier, H; Teissier, R | 1 |
| McBride, KL; Seagraves, NJ | 1 |
| Kale, A; Kale, E | 1 |
| Tatò, L; Zaffanello, M; Zamboni, G | 1 |
| Espinar, A; Guerrero, JM; Marchante, C; Martinez-Cruz, F; Osuna, C; Pozo, D | 1 |
| Ahmed, L; Boyle, DW; Denne, SC; Liechty, EA; Shen, W; Wisniowski, P | 1 |
| Dale, Y; Ike, J; Mackey, V; Maleque, M; Mushi, R; Nyanda, A | 1 |
| Gurry, D; Ng, TW; Rae, A; Wray, J; Wright, H | 1 |
| GARZO, T; HANSSON, E; ULLBERG, S | 1 |
| BOGGS, DE; WAISMAN, HA | 1 |
| HECHT-LUCARI, G; LUCISANO, F | 1 |
| OEPEN, H; OEPEN, I | 1 |
| Azen, C; de la Cruz, F; Friedman, EG; Güttler, F; Hanley, W; Koch, R; Levy, H; Matalon, K; Matalon, R; Ning, J; Platt, L; Rouse, B; Trefz, F; Waisbren, S; Widaman, K | 1 |
| Azen, C; de la Cruz, F; Guldberg, P; Güttler, F; Hanley, WB; Koch, R; Levy, HL; Matalon, R; Romstad, A; Rouse, BM; Trefz, F | 1 |
| Acosta, PB; Azen, C; Matalon, KM | 1 |
| Azen, C; Widaman, KF | 1 |
| Azen, C; Waisbren, SE | 1 |
| Azen, CG; de la Cruz, F; Güttler, F; Hanley, WB; Koch, R; Levy, HL; Matalon, R; Rouse, B; Trefz, FK; Waisbren, SE | 1 |
| Baudin, J; Lee, PJ; Lilburn, M | 1 |
| Blau, N; Trefz, FK | 1 |
| Antshel, KM; Waisbren, SE | 1 |
| Azen, C; Rouse, B | 1 |
| Barbellion, S; Bergmann, B; Brunel, P; Clark, RL; Crofts, F; DeLise, B; Guittin, P; Hofmann, T; Lerman, S; Pino, M; Potdevin, S | 1 |
| Barbellion, S; Brunel, P; Clark, R; Crofts, F; DeLise, B; Guittin, P; Hofmann, T; Lerman, S; Lockey, P; Nguyen, M; Pino, M; Rohatagi, S; Schmidt, J; Wong, M; Zhang, J | 1 |
| Bailey, I; Brereton, H; Gennaccaro, M; Gleason, S; Goss, B; Lesperance, E; Levy, H; Moseley, K; Munier, A; Rohr, F; Singh, R; Sullivan, D; Tonyes, L; Vespa, H; Waisbren, S | 1 |
| Cooper, JA; Herrick, TM | 1 |
| Calvin, J; Hogg, SL; Reading, R; Shaw-Smith, C; Trump, D | 1 |
| Chien, YH; Hwu, WL; Liu, HM; Peng, SS; Tseng, WY | 1 |
| Annichino-Bizzacchi, JM; Barbosa, HC; Barini, R; Carvalho, EC; Costa, DS; Siqueira, LH | 1 |
| Artuch, R; Campistol, J; Gómez, L; Gutiérrez, A; Lambruschini, N; Mas, A; Mila, M; Pérez-Dueñas, B; Pineda, J; Vilaseca, MA | 1 |
| Boyd-Kimball, D; Butterfield, DA; Mohmmad Abdul, H; Reed, T; Sultana, R | 1 |
| Gomes-Marcondes, MC; Mello, MA; Ventrucci, G | 1 |
| Cockburn, F; Lee, PJ; Ridout, D; Walter, JH | 1 |
| Antshel, KM; Gurian, EA; Waisbren, SE | 1 |
| de Boo, HA; Harding, JE; Kulik, W; Lafeber, HN; Smith, DE; van Zijl, PL | 1 |
| Gurekian, CN; Koski, KG | 1 |
| Guerrero, JM; Martínez-Cruz, F; Osuna, C | 1 |
| Guttler, F; Koch, R; Moseley, K | 1 |
| Kaźmierkiewicz, R; Lammek, B; Smiech, B | 1 |
| Ashokkumar, N; Pari, L; Rao, ChA | 1 |
| Butkevich, IP; Makukhina, GV; Mikhaĭlenko, VA | 1 |
| Funakoshi-Tago, M; Ihle, JN; Moritake, H; Parganas, E; Pelletier, S | 1 |
| Gilles, FH; Koch, R; Verma, S | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Broquist, HP; Fleming, AF | 1 |
| Huntley, CC; Stevenson, RE | 2 |
| Waisman, HA | 1 |
| Hudson, FP | 1 |
| Arakawa, T; Dancis, J; Hutzler, J; Morikawa, T; Tada, K; Wada, Y | 1 |
| Kerr, GR; Waisman, HA | 1 |
| Brown, ES; Waisman, HA | 2 |
| Leeming, RJ | 1 |
| Fulton, T; Loo, YH; Miller, K; Wisniewski, HM | 1 |
| Butler, IJ; Howell, RR; O'Flynn, ME; Seifert, WE | 1 |
| Keefer, CL; Tasca, RJ | 1 |
| Chou, JY; Mano, T; Sakiyama, T | 1 |
| Culvenor, JG; Ferber, E; Harris, AW; Mandel, TE; Whitelaw, A | 1 |
| Arai, H; Itakura, M; Jeng, C; Kurihara, S; Nozawa, S; Ohta, H; Suzuki, K; Tamura, S | 1 |
| Boylan, JM; Jackson, BT; Piasecki, GJ; Pueschel, SM | 3 |
| Boylan, JM; Cha, CJ; Jackson, BT; Piasecki, GJ; Pueschel, SM | 2 |
| Chamove, AS | 2 |
| Güttler, F | 1 |
| Fulton, TR; Loo, YH; Rabe, A; Triano, T | 1 |
| Berry, HK; Butcher, RE; Vorhees, CV | 1 |
| Hicks, RE; Kirkman, HN | 1 |
| Berndt, WO; Mayura, K; Parker, R; Phillips, TD | 1 |
| Jansen, GR; Masor, M; Sampson, DA | 1 |
| Lyon, IC | 1 |
| Fishman, WH; Kurihara, S; Nozawa, S; Ohta, H; Udagawa, Y | 1 |
| Levy, HL; Waisbren, SE | 2 |
| Finch, CA; Grace, R; Mackler, B; Person, R; Shepard, TH | 1 |
| Iwata, M; Nishijima, M | 1 |
| Bartley, J; Beuhler, B; Lipson, A; O'Halloran, M; Walsh, D; Webster, W; Yu, J | 1 |
| Jarosch, E; Plöchl, E; Rittinger, O | 1 |
| Buist, NR; Lis, E; Penn, R; Tuerck, J | 1 |
| Cervenka, J; Dolezal, A; Homolka, J; Hoza, J; Hyánek, J; Kapras, J; Losan, F; Malá, M; Nevsímalová, S; Seemanová, E; Srácek, J; Tresohlavá, Z; Trnka, J; Vácha, V; Viletová, H | 1 |
| Blaskovics, M; Koch, R | 1 |
| Azama, F; Maslow, WC; Muensch, HA; Schneider, AS | 1 |
| Billmire, K; Dygert, MK; Ingwall, JS; Ouellette, AJ; Watson, RK | 1 |
| Cotton, RG; Danks, DM; Firgaira, FA; Fowler, K; Lipson, A; Yu, JS | 1 |
| Dhont, JL; Farriaux, JP | 1 |
| Corbeel, L | 1 |
| Fishler, K; Koch, R; Lenke, RR; Platt, LD | 1 |
| Cole, DE; Grenier, A; Houghton, SA; Laberge, C; Levy, HL; Scriver, CR | 1 |
| Clow, CL; Scriver, CR | 3 |
| Kalkhoff, RK; Rushakoff, RJ | 1 |
| Eaton, BM; Yudilevich, DL | 2 |
| Lenke, RR; Levy, HL | 2 |
| Stroud, HW; Tenbrinck, MS | 1 |
| Fishman, WH; Millán, JL; Ruoslahti, E; Stigbrand, T | 1 |
| Acosta, PB; Blaskovics, M; Cloud, H; Lis, E; Stroud, H; Wenz, E | 1 |
| Justice, CL; Michels, VV | 1 |
| Belfield, A; Hutchison, RS; McLelland, AS; Pledger, DR; Steele, CJ | 1 |
| Cabalska, B; Duczyńska, N; Nowaczewska, I | 1 |
| Eaton, BM; Mann, GE; Yudilevich, DL | 1 |
| Kirkman, HN | 1 |
| Máté, M; Somogyi, C; Szabó, L | 1 |
| Laguna Serrano, C | 1 |
| Brass, CA; Greengard, O; Isaacs, CE; McChesney, R | 1 |
| Batshaw, ML; Bessman, SP; Valle, D | 1 |
| Krebs, H; Lauder, JM; Sze, PY | 1 |
| Davidson, DC; Ireland, JT; Isherwood, DM; Rae, PG | 1 |
| Ardouin, P; Dhondt, JL; Farriaux, JP; Hayte, JM | 1 |
| Lorijn, RH; Sengers, RC; Trijbels, JM | 1 |
| Crain, S; Tewari, S | 1 |
| Fyfe, WM; Hart, DM; Scott, TM | 1 |
| Crie, JS; Wildenthal, K | 1 |
| Bakker, JG; Meijer, GA; Van der Koelen, CJ; Van der Meulen, J; Van Vuuren, AM | 1 |
| Bohlender, J; Corvol, P; Crain, P; Helin, C; Inoue, I; Jeunemaitre, X; Lalouel, JM; Lifton, RP; Rohrwasser, A; Ward, K | 1 |
| Azen, C; de la Cruz, F; Friedman, EG; Güttler, F; Hanley, WB; Koch, R; Levy, HL; Matalon, R; Rouse, B; Trefz, F | 1 |
| Allen, RJ; Brunberg, J; Jackson, G; Schaefer, AM; Schwartz, E | 1 |
| Azen, C; de la Cruz, F; Friedman, E; Hanley, WB; Koch, R; Matalon, R; Michals, K; Rouse, B | 1 |
| Smith, I; Tillotson, S | 1 |
| Backwell, FR; Beever, DE; Bequette, BJ; Calder, AG; Dhanoa, MS; Lobley, GE; Metcalf, JA; Sutton, JD; Walker, A; Wray-Cahen, D | 1 |
| Matthieu, JM | 1 |
| Allred, E; Barwell, BE; Levy, HL; Lobbregt, D; Sardharwalla, IB; Schuler, A; Schweitzer, SM; Trefz, FK; Waisbren, SE; Walter, JH | 1 |
| Dobbs, JM; Goss, BS; Guldberg, P; Güttler, F; Levy, HL; Michals-Matalon, K; Sullivan, DK | 1 |
| Clarke, JT; Hanley, WB; Johnson, JM; Lehotay, DC; Schoonheyt, WE | 1 |
| Chester-Jones, H; Davis, DL; Goodband, RD; Johnston, LJ; Pettigrew, JE; Rettmer, I; Rozeboom, DW; Rust, JW; Stevenson, JS; Tokach, MD | 1 |
| Inui, K; Manabe, S; Uenishi, K | 1 |
| Argilés, JM; Carbó, N; López-Soriano, FJ | 1 |
| Peat, B | 1 |
| Azen, C; Hanley, W; Koch, R; Levy, HL; Matalon, R; Rouse, B | 1 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD | 1 |
| Imamura, T; Isshiki, G; Nakajima, T; Oura, T; Sawada, Y; Shintaku, H | 2 |
| Chien, PF; Rennie, MJ; Scrimgeour, CM; Smith, K; Taylor, DJ; Watt, PW | 1 |
| Hyánek, J | 1 |
| Goldin, KR | 1 |
| Dhondt, JL; Farriaux, JP; Lacombe, A; Largillière, C; Puech, F; Valat, S | 1 |
| Bernstein, J; Brand, N; Elitzur, A; Kleiman, S; Schwartz, G; Shiloh, Y; Vanagaite, L; Woo, SL | 1 |
| Kecskemethy, HH; Levy, HL; Lobbregt, D | 1 |
| Azen, C; Castiglioni, L; Friedman, EG; Koch, R; Levy, H; Matalon, R; Michals-Matalon, K; Rohr, F; Rouse, B; Wenz, E | 1 |
| Legge, M | 1 |
| Bendl, J; Dolezal, A; Hyánek, J; Kozich, V; Kubík, M; Soukup, K; St'astná, S; Viletová, H; Zeman, J | 1 |
| Barnes, PD; Levy, HL; Lobbregt, D; Poussaint, TY | 1 |
| Baron, AD; Brechtel, G; Denne, SC; Golichowski, AM; Karn, CA; Zimmer, DM | 1 |
| Bowsher, RR; Boyle, DW; Denne, SC; Lee, WH; Liechty, EA; Moorehead, H | 1 |
| Clark, BJ; Cockburn, F | 2 |
| Acosta, PB; Austin, V; Azen, C; Castiglioni, L; Michals, K; Rohr, F; Wenz, E | 1 |
| Brenton, DP; Lilburn, M | 1 |
| Boyd, CA; Kudo, Y | 2 |
| Ashton-Prolla, P; Giugliani, R; Jardim, LB; Palma-Dias, R; Silva, LC | 1 |
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58 review(s) available for phenylalanine and Pregnancy
| Article | Year |
|---|---|
Phenylketonuria and the brain.
Topics: Animals; Brain; Child; Female; Humans; Microcephaly; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2023 |
Phenylalanine hydroxylase deficiency treatment and management: A systematic evidence review of the American College of Medical Genetics and Genomics (ACMG).
Topics: Female; Genetics, Medical; Genomics; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; United States | 2023 |
Similarities and differences in key diagnosis, treatment, and management approaches for PAH deficiency in the United States and Europe.
Topics: Adolescent; Adult; Diet; Europe; Female; Genomics; Humans; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; United States | 2020 |
Phenylketonuria: Current Treatments and Future Developments.
Topics: Female; Genetic Therapy; Genotype; Humans; Mutation; Phenotype; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 2019 |
[Maternal phenylketonuria].
Topics: Adult; Biomarkers; Female; Humans; Hungary; Infant, Newborn; Male; Neonatal Screening; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Preconception Care; Pregnancy | 2013 |
Recommendations for the nutrition management of phenylalanine hydroxylase deficiency.
Topics: Evidence-Based Medicine; Female; Humans; Patient Compliance; Phenylalanine; Phenylketonurias; Practice Guidelines as Topic; Pregnancy; Tyrosine | 2014 |
Medical Problems in Obstetrics: Inherited Metabolic Disease.
Topics: Abortion, Spontaneous; Breast Feeding; Developmental Disabilities; Female; Galactosemias; Humans; Infertility, Female; Metabolism, Inborn Errors; Nausea; Phenylalanine; Phenylketonuria, Maternal; Postnatal Care; Preconception Care; Pregnancy; Pregnancy Complications; Teratogenesis; Vomiting | 2015 |
KIFC1: a promising chemotherapy target for cancer treatment?
Topics: Alanine; Antineoplastic Agents; Centrosome; DNA; Female; Humans; Kinesins; Mitosis; Molecular Targeted Therapy; Neoplasms; Oocytes; ortho-Aminobenzoates; Phenanthrenes; Phenylalanine; Pregnancy; Protein Transport; Pyridines; Signal Transduction; Spermatogenesis | 2016 |
Updated, web-based nutrition management guideline for PKU: An evidence and consensus based approach.
Topics: Adult; Consensus; Evidence-Based Medicine; Female; Humans; Infant, Newborn; Nutrition Policy; Nutrition Therapy; Phenylalanine; Phenylketonurias; Practice Guidelines as Topic; Pregnancy; Recommended Dietary Allowances | 2016 |
Undiagnosed maternal phenylketonuria: own clinical experience and literature review.
Topics: Abortion, Eugenic; Adult; Delayed Diagnosis; Female; Heart Septal Defects, Ventricular; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Diagnosis | 2009 |
Recent advances in our understanding of protein and amino acid metabolism in the human fetus.
Topics: Albumins; Amino Acids; Biological Transport; Female; Fetus; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Prenatal Nutritional Physiological Phenomena; Proteins; Time Factors; Tyrosine | 2010 |
[Phenylketonuria--toward a better carry-over care].
Topics: Adolescent; Adult; Amino Acids, Neutral; Biopterins; Continuity of Patient Care; Diet Therapy; Female; Humans; Infant, Newborn; Insurance, Life; Neonatal Screening; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Socioeconomic Factors; Young Adult | 2010 |
Maternal phenylketonuria and hyperphenylalaninemia in pregnancy: pregnancy complications and neonatal sequelae in untreated and treated pregnancies.
Topics: Congenital Abnormalities; Developmental Disabilities; Facial Bones; Female; Humans; Infant, Newborn; Infant, Small for Gestational Age; Intellectual Disability; Microcephaly; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimesters; Skull | 2012 |
Phenylketonuria: 50 years since Følling's discovery and still expanding our clinical and biochemical knowledge.
Topics: Adolescent; Adult; Child; Child, Preschool; Denmark; Diet Therapy; Female; History, 20th Century; Humans; Infant; Infant, Newborn; Male; Mass Screening; Phenylalanine; Phenylketonurias; Pregnancy | 1984 |
Progress in experimental phenylketonuria: a critical review.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Energy Metabolism; Female; Fenclonine; Glutamates; Humans; Mice; Myelin Sheath; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Protein Biosynthesis; Pyridoxine; Serotonin | 1981 |
Phenylketonuria: epitome of human biochemical genetics (first of two parts).
Topics: Animals; Biopterins; Brain; Chromosome Mapping; Female; Homeostasis; Humans; Intellectual Disability; Liver; Mutation; Myelin Proteins; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy | 1980 |
Phenylketonuria and other phenylalanine hydroxylation mutants in man.
Topics: Alleles; Amino Acid Metabolism, Inborn Errors; Animals; Biopterins; Dihydropteridine Reductase; Female; Fetal Diseases; Gene Frequency; Genetic Carrier Screening; Heterozygote; Humans; Hydroxylation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats | 1980 |
MRI characterization of cerebral dysgenesis in maternal PKU.
Topics: Abnormalities, Multiple; Brain; Female; Heart Defects, Congenital; Humans; Magnetic Resonance Imaging; Microcephaly; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 1994 |
[Maternal phenylketonuria].
Topics: Female; Humans; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prognosis | 1998 |
Treating phenylketonuria by a phenylalanine-free diet.
Topics: Adult; Child; Child Nutrition Sciences; Female; Humans; Parents; Phenylalanine; Phenylketonurias; Pregnancy | 1998 |
New approaches to the treatment of phenylketonuria.
Topics: Animals; Diet; Female; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy | 1999 |
Undiagnosed maternal phenylketonuria: the need for prenatal selective screening or case finding.
Topics: Adolescent; Adult; Female; Fetal Diseases; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Retrospective Studies | 1999 |
[Phenylketonuria: a children's disease in adulthood].
Topics: Adult; Child; Congenital Abnormalities; Female; Humans; Male; Mental Disorders; Netherlands; Neuropsychological Tests; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2000 |
[Maternal PKU fetal effects].
Topics: Abnormalities, Multiple; Diet; Female; Humans; Infant, Newborn; Intellectual Disability; Mass Screening; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prenatal Exposure Delayed Effects; Prognosis; Syndrome | 2000 |
Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets.
Topics: Amino Acids; Circadian Rhythm; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Food, Fortified; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Taste; Tyrosine | 2001 |
Impaired arachidonic (20:4n-6) and docosahexaenoic (22:6n-3) acid synthesis by phenylalanine metabolites as etiological factors in the neuropathology of phenylketonuria.
Topics: Adult; Animals; Arachidonic Acid; Brain; Brain Diseases, Metabolic; Child; Disease Models, Animal; Docosahexaenoic Acids; Female; Humans; Infant; Infant, Newborn; Male; Mice; Mitochondria; Models, Biological; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2001 |
Foetal amino acids.
Topics: Amino Acids; Amniotic Fluid; Animals; Dietary Proteins; Female; Fetal Blood; Fetus; Gestational Age; Humans; Insulin; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Time Factors; Umbilical Arteries | 1977 |
[Diagnosis and management of the aminoacidopathies (author's transl)].
Topics: Amino Acid Metabolism, Inborn Errors; Citric Acid Cycle; Female; Genotype; Homocysteine; Humans; Lysine; Phenylalanine; Pregnancy; Prenatal Diagnosis | 1978 |
[Phenylketonuria yesterday and today. Evaluation of the work of systematic neonatal screening].
Topics: Female; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 1992 |
[Genetics and hyperphenylalaninemias in 1992].
Topics: Adolescent; Adult; Aged; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Ethnicity; Female; Genetic Carrier Screening; Genetic Counseling; Genetic Therapy; Haplotypes; Humans; Infant; Infant, Newborn; Male; Middle Aged; Mutagenesis; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Polymorphism, Restriction Fragment Length; Pregnancy | 1992 |
[Differential diagnosis and therapy of various forms of hyperphenylalaninemia: facts and fiction].
Topics: Biopterins; Diagnosis, Differential; Female; Humans; Infant, Newborn; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications | 1992 |
Transport of amino acids across the blood-brain barrier: implications for treatment of maternal phenylketonuria.
Topics: Animals; Blood-Brain Barrier; Female; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy | 1990 |
Transport of amino acids by the human placenta: predicted effects thereon of maternal hyperphenylalaninaemia.
Topics: Female; Humans; Maternal-Fetal Exchange; Microvilli; Phenylalanine; Phenylketonurias; Placenta; Pregnancy | 1990 |
Cardiac defects in the children of mothers with high concentrations of plasma phenylalanine.
Topics: Female; Heart Defects, Congenital; Humans; Infant, Newborn; Neural Crest; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1990 |
[Detection, differential diagnosis, and prenatal diagnosis of tetrahydrobiopterin deficiency].
Topics: Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Diagnosis, Differential; Female; Guanosine Triphosphate; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylalanine; Phosphorus-Oxygen Lyases; Pregnancy; Prenatal Diagnosis | 1987 |
Progress in the identification of the heterozygote in phenylketonuria.
Topics: Breath Tests; Fasting; Female; Genetic Carrier Screening; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Polymorphism, Restriction Fragment Length; Pregnancy; Prenatal Diagnosis; Tyrosine | 1989 |
[Results, problems and consequences of early treatment of phenylketonuria].
Topics: Child; Child Development; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Mass Screening; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Diagnosis | 1989 |
Use of aspartame in pregnancy.
Topics: Aspartame; Aspartic Acid; Digestion; Dipeptides; Female; Fetus; Humans; Methanol; Phenylalanine; Pregnancy | 1985 |
Hyperphenylalaninemia syndromes: current status of diagnosis and management.
Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Female; Humans; Hydroxylation; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Diagnosis; Syndrome | 1988 |
Maternal phenylketonuria: cause for concern among women with PKU.
Topics: Female; Fetal Diseases; Humans; Infant, Newborn; Intellectual Disability; Intelligence; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1987 |
Tetrahydrobiopterin biosynthetic pathway and deficiency.
Topics: Alcohol Oxidoreductases; Biopterins; Female; Humans; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pregnancy; Prenatal Diagnosis | 1987 |
Review of current practices in management of inherited disorders of amino acid metabolism in Western Europe.
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Biopterins; Diet; Dietary Proteins; Dihydropteridine Reductase; Europe; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Infant, Newborn; Intellectual Disability; Liver; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Prognosis; Pterins; Tyrosine | 1986 |
Neurotoxicology of food additives.
Topics: Animals; Aspartame; Blood-Brain Barrier; Dietary Carbohydrates; Dietary Proteins; Dipeptides; Emotions; Female; Food Additives; Maximum Allowable Concentration; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Seizures; Sleep Initiation and Maintenance Disorders; Tyrosine; United States; United States Food and Drug Administration | 1986 |
Biochemical basis for nutritional management of preterm infants.
Topics: Acetoacetates; Adenosine Triphosphate; Amino Acids; Animals; Brain; Cyclic AMP; Cystathionine; Cystine; Enzyme Induction; Female; Fumarates; Homogentisic Acid; Humans; Hydro-Lyases; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Liver; Lyases; Maternal-Fetal Exchange; Methionine; Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pregnancy; S-Adenosylmethionine; Transferases; Tyrosine; Tyrosine Transaminase | 1974 |
Developmental studies on some enzymes associated with 'detoxication'.
Topics: Alcohol Oxidoreductases; Animals; Biotransformation; Chick Embryo; Cytosol; Enzyme Induction; Female; Fetus; Glucose; Glucuronates; Glucuronidase; Glucuronosyltransferase; Hexosyltransferases; Hydrocortisone; Liver; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenylalanine; Pregnancy; Pyrophosphatases; Ribonucleases; Uridine Diphosphate Sugars | 1973 |
[Congenital disorders of phenylalanine metabolism].
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Transferases | 1973 |
Aminoacidurias due to inherited disorders of metabolism (first of two parts).
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Cystathionine; Cysteine; Cystine; Disulfides; Female; Homocystinuria; Humans; Infant, Newborn; Lactates; Male; Methionine; Oxidoreductases; Phenylalanine; Phenylketonurias; Pregnancy; Pyruvates; Sulfhydryl Compounds; Sulfites; Sulfur; Tyrosine | 1973 |
Carcinoplacental isoenzyme antigens.
Topics: Alkaline Phosphatase; Antigens, Neoplasm; Carcinoembryonic Antigen; Electrophoresis, Starch Gel; Female; HeLa Cells; Hot Temperature; Humans; Isoenzymes; Leucine; Male; Microscopy, Electron; Neoplasm Metastasis; Phenotype; Phenylalanine; Placenta; Placental Extracts; Pregnancy | 1973 |
Metabolic changes in the blastocysts of mice and rats during delayed implantation.
Topics: Amino Acids; Animals; Blastocyst; Carbon Dioxide; Carbon Radioisotopes; Castration; Culture Media; Embryo Implantation; Estrogens; Female; Glucose; Glutamates; Lactation; Methionine; Mice; Phenylalanine; Pregnancy; Pregnancy, Animal; Progesterone; Protein Biosynthesis; Rats; Sulfur Radioisotopes; Time Factors | 1974 |
Neonatal screening for inborn errors of amino acid metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Biological Assay; Chromatography, Paper; Evaluation Studies as Topic; Female; Hartnup Disease; Histidine; Homocystinuria; Humans; Infant, Newborn; Leucine; Maple Syrup Urine Disease; Mass Screening; Methionine; Methods; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1974 |
Hyperphenylalaninemia and pregnancy.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Child; Female; Haplorhini; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Intelligence Tests; Male; Mass Screening; Microcephaly; Phenylalanine; Pregnancy; Pregnancy Complications | 1972 |
Perinatal determinants of emotionality.
Topics: Animals; Animals, Newborn; Diet; Emotions; Female; Fetus; Genetics, Behavioral; Hormones; Humans; Male; Mice; Phenylalanine; Postpartum Period; Pregnancy; Rats; Stress, Psychological | 1969 |
Some polypeptides influencing gastric-acid secretion.
Topics: Amides; Animals; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry; Cysteine; Dogs; Female; Gastric Juice; Gastrins; Gastrointestinal Hormones; Humans; Methionine; Peptides; Phenylalanine; Pregnancy; Propionates; Serine; Sheep; Swine; Tryptophan | 1970 |
Phenylketonuria and its variants.
Topics: Adult; Child, Preschool; Congenital Abnormalities; Female; Gene Frequency; Growth Disorders; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Middle Aged; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1970 |
The clinical use of chloramphenicol.
Topics: Anemia, Aplastic; Chemical Phenomena; Chemistry; Chloramphenicol; Eye Diseases; Female; Hematologic Diseases; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infections; Melioidosis; Phenylalanine; Pregnancy; Respiratory Tract Infections; Rickettsia Infections; Salmonella Infections; Sepsis; Tularemia | 1970 |
Phenylketonuria: a review.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Congenital Abnormalities; Diet Therapy; Female; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intellectual Disability; Mass Screening; Minerals; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Time Factors; Transaminases; Vitamins | 1970 |
The offspring of phenylketonuric women.
Topics: Abortion, Spontaneous; Adult; Birth Weight; Black or African American; Brain Chemistry; Breast Feeding; Child, Preschool; Congenital Abnormalities; Diet Therapy; Female; Glutamine; Heart Auscultation; Heterozygote; Hexokinase; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Intelligence Tests; Male; Maryland; Microcephaly; Myelin Sheath; Nerve Tissue Proteins; Phenylacetates; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Care; Pyruvate Kinase; Umbilical Cord | 1971 |
[Study on experimental phenylketonuria].
Topics: Amino Acids; Animals; Brain; Female; Haplorhini; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Tyrosine | 1968 |
10 trial(s) available for phenylalanine and Pregnancy
| Article | Year |
|---|---|
Protein requirements of healthy pregnant women during early and late gestation are higher than current recommendations.
Topics: Adult; Carbon Isotopes; Diet; Dietary Proteins; Energy Intake; Energy Metabolism; Female; Gestational Age; Humans; Maternal Nutritional Physiological Phenomena; Nutrition Policy; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Pregnancy | 2015 |
Knowledge, compliance and serum phenylalanine concentrations in adolescents and adults with phenylketonuria and the effect of a patient-focused educational resource.
Topics: Adolescent; Adult; Dietary Proteins; Female; Health Knowledge, Attitudes, Practice; Humans; Male; Patient Compliance; Patient Education as Topic; Phenylalanine; Phenylketonurias; Pregnancy; Surveys and Questionnaires | 2008 |
The Maternal Phenylketonuria International Study: 1984-2002.
Topics: Analysis of Variance; Birth Weight; Child; Child, Preschool; Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Intelligence; Logistic Models; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Pregnancy Outcome; Prenatal Care; Statistics, Nonparametric | 2003 |
The Resource Mothers Study of Maternal Phenylketonuria: preliminary findings.
Topics: Female; Fetal Diseases; Gestational Age; Humans; Patient Compliance; Peer Group; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Care; Program Evaluation; Social Support | 2004 |
Tetrahydrobiopterin responsiveness in patients with phenylketonuria.
Topics: Adolescent; Adult; Biopterins; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Mutation; Phenotype; Phenylalanine; Phenylketonurias; Pregnancy | 2004 |
Arginine and mixed amino acids increase protein accretion in the growth-restricted and normal ovine fetus by different mechanisms.
Topics: Amino Acids; Animals; Arginine; Catheterization; Embolism; Female; Fetal Growth Retardation; Fetal Proteins; Fetus; Gas Chromatography-Mass Spectrometry; Kinetics; Oxygen; Phenylalanine; Pregnancy; Pregnancy, Animal; Sheep; Time Factors | 2005 |
The international collaborative study of maternal phenylketonuria: status report 1994.
Topics: Adult; Case-Control Studies; Female; Humans; International Cooperation; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Prospective Studies | 1994 |
Maternal PKU Collaborative Study: pregnancy outcome and postnatal head growth.
Topics: Canada; Female; Head; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; United States | 1994 |
The North American Collaborative Study of Maternal Phenylketonuria. Status report 1993.
Topics: Adolescent; Adult; Anthropometry; Energy Intake; Female; Fetal Diseases; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence Tests; Morbidity; Neonatal Screening; North America; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Prospective Studies | 1993 |
Alkaline phosphatase histochemistry and biochemistry in the diagnosis of complete hydatidiform mole.
Topics: Alkaline Phosphatase; Biomarkers, Tumor; Chorionic Villi; Clinical Enzyme Tests; Enzyme Inhibitors; Female; GPI-Linked Proteins; Homoarginine; Humans; Hydatidiform Mole; Immunoenzyme Techniques; Isoenzymes; Phenylalanine; Placenta; Pregnancy; Prognosis; Uterine Neoplasms | 2000 |
554 other study(ies) available for phenylalanine and Pregnancy
| Article | Year |
|---|---|
Preventing maternal phenylketonuria (PKU) syndrome: important factors to achieve good metabolic control throughout pregnancy.
Topics: Adult; Austria; Female; Germany; Humans; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Syndrome | 2021 |
Studies on teratogenic effect of ochratoxin A given via mouldy diet in mice in various sensitive periods of the pregnancy and the putative protection of phenylalanine.
Topics: Animals; Diet; Female; Mice; Ochratoxins; Phenylalanine; Pregnancy; Teratogenesis | 2022 |
Neurotoxicity of phenylalanine on human iPSC-derived cerebral organoids.
Topics: Female; Humans; Induced Pluripotent Stem Cells; Microcephaly; Organoids; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2022 |
Recommendations on phenylketonuria in Turkey.
Topics: Amino Acids; Biopterins; Child; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Turkey | 2022 |
New insights into the effect of bisphenol AF exposure on maternal mammary glands at various stages of gestation in mice.
Topics: Amino Acids; Ammonia; Animals; Benzhydryl Compounds; Female; Fluorocarbons; Mice; Ornithine; Phenylalanine; Pregnancy; Proline; RNA, Messenger; Threonine; Tyrosine; Valine | 2022 |
The effects of aspartame on the HTR8/SVneo extravillous trophoblast cell line.
Topics: Aspartame; Aspartic Acid; Cell Line; Cell Movement; Female; Glucose; Humans; Methanol; Phenylalanine; Placenta; Pregnancy; Trophoblasts | 2022 |
Impact of pregnancy planning and preconceptual dietary training on metabolic control and offspring's outcome in phenylketonuria.
Topics: Child; Child Behavior; Diet; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Pregnancy Outcome; Retrospective Studies; Syndrome | 2022 |
Impact of dietary supplementation with N-carbamoyl-aspartic acid on serum metabolites and intestinal microflora of sows.
Topics: Animal Feed; Animals; Arginine; Aspartic Acid; Birth Weight; Colostrum; Diet; Dietary Supplements; Female; Gastrointestinal Microbiome; Lactation; Phenylalanine; Pregnancy; Proline; Swine; Tyrosine | 2023 |
Characterization of Choline Nutriture among Adults and Children with Phenylketonuria.
Topics: Adult; Child; Choline; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Phenylalanine; Phenylketonurias; Pregnancy; Vitamin B 12; Vitamins | 2022 |
The impact of phenylalanine levels during pregnancy on birth weight and later development in children born to women with phenylketonuria.
Topics: Birth Weight; Child; Diet; Family; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2023 |
Untargeted metabolomics and lipidomics to assess plasma metabolite changes in dairy goats with subclinical hyperketonemia.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Fatty Acids, Nonesterified; Female; Goat Diseases; Goats; Ketosis; Lactation; Lipidomics; Metabolomics; Oleic Acids; Phenylalanine; Pregnancy | 2023 |
Discovery of novel metabolic signatures for early identification of women at risk of developing gestational hypertension.
Topics: Female; Histidine; Humans; Hypertension, Pregnancy-Induced; Metabolomics; Phenylalanine; Pre-Eclampsia; Pregnancy | 2023 |
Blood phenylalanine fluctuation in phenylketonuric children treated by BH4 or low-phenylalanine diet from birth.
Topics: Child; Diet; Female; Humans; Infant, Newborn; Parturition; Phenylalanine; Phenylketonurias; Pregnancy; Retrospective Studies | 2023 |
Aromatic Amino Acids and Their Interactions with Gut Microbiota-Related Metabolites for Risk of Gestational Diabetes: A Prospective Nested Case-Control Study in a Chinese Cohort.
Topics: Amino Acids, Aromatic; Case-Control Studies; Diabetes, Gestational; East Asian People; Female; Gastrointestinal Microbiome; Humans; Phenylalanine; Pregnancy; Prospective Studies; Tryptophan | 2023 |
Towards precision medicine for phenylketonuria: The effect of restoring a strict metabolic control in adult patients with early-treated phenylketonuria.
Topics: Adult; Cognition; Female; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Precision Medicine; Pregnancy | 2023 |
Discrimination of blood metabolomics profiles in neonates with idiopathic polyhydramnios.
Topics: Alanine; Asparagine; Aspartic Acid; Cesarean Section; Child; Chromatography, Liquid; Female; Glutamates; Homocysteine; Humans; Infant, Newborn; Phenylalanine; Polyhydramnios; Pregnancy; RNA, Transfer; Serine; Tandem Mass Spectrometry | 2023 |
Health-related quality of life in a european sample of adults with early-treated classical PKU.
Topics: Adult; Cross-Sectional Studies; Female; Health Status; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Pregnancy; Quality of Life | 2023 |
Metabolomic markers of antepartum depression and suicidal ideation.
Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Depression; Female; Humans; Logistic Models; Metabolomics; Odds Ratio; Patient Health Questionnaire; Peru; Phenylalanine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnant Women; Prospective Studies; Risk Factors; Suicidal Ideation; Triglycerides; Young Adult | 2020 |
Dietary phenylalanine requirements during early and late gestation in healthy pregnant women.
Topics: Adult; Amino Acids; Carbon Dioxide; Carbon Isotopes; Dose-Response Relationship, Drug; Female; Humans; Linear Models; Meals; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Pregnancy | 2020 |
Vaginal metabolome: towards a minimally invasive diagnosis of microbial invasion of the amniotic cavity in women with preterm labor.
Topics: Acetylcholine; Adult; Amniocentesis; Bacterial Infections; Case-Control Studies; Choline; Chorioamnionitis; Cohort Studies; Female; Glutamine; Humans; Hypoxanthine; Magnetic Resonance Spectroscopy; Metabolome; Obstetric Labor, Premature; Phenylalanine; Pregnancy; Proline; Vagina; Young Adult | 2020 |
Management of Women With Phenylalanine Hydroxylase Deficiency (Phenylketonuria): ACOG Committee Opinion Summary, Number 802.
Topics: Family Planning Services; Female; Genetic Counseling; Humans; Infant, Newborn; Neonatal Screening; Obstetrics; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prenatal Care; Societies, Medical; United States | 2020 |
Management of Women With Phenylalanine Hydroxylase Deficiency (Phenylketonuria): ACOG Committee Opinion, Number 802.
Topics: Family Planning Services; Female; Genetic Counseling; Humans; Infant, Newborn; Neonatal Screening; Obstetrics; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prenatal Care; Societies, Medical; United States | 2020 |
The first study of successful pregnancies in Chinese patients with Phenylketonuria.
Topics: Adult; Biopterins; China; Diet; Disease Management; Female; Humans; Infant, Newborn; Maternal Nutritional Physiological Phenomena; Neonatal Screening; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Young Adult | 2020 |
Proteolytic Volatile Profile and Electrophoretic Analysis of Casein Composition in Milk and Cheese Derived from Mironutrient-Fed Cows.
Topics: Animal Feed; Animals; Caseins; Cattle; Cheese; Chromatography, Gas; Diet; Dietary Supplements; Electrophoresis, Polyacrylamide Gel; Female; Gelatinases; Iodine; Lactation; Leucine; Mass Spectrometry; Milk; Pentanols; Phenylalanine; Pregnancy; Protein Isoforms; Proteolysis; Selenium; Volatile Organic Compounds; Zinc | 2020 |
Maternal PKU: Defining phenylalanine tolerance and its variation during pregnancy, according to genetic background.
Topics: Adult; Diet, Protein-Restricted; Female; Fetal Growth Retardation; Genetic Predisposition to Disease; Gestational Weight Gain; Heart Defects, Congenital; Humans; Live Birth; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Pregnancy; Risk Factors; Solitary Kidney; Treatment Outcome; Young Adult | 2020 |
Comparison of phenylalanine tolerance in singleton and twin pregnancies in patients with phenylketonuria.
Topics: Diet; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy, Twin | 2020 |
Dietary Aromatic Amino Acid Requirements During Early and Late Gestation in Healthy Pregnant Women.
Topics: Adult; Amino Acids, Aromatic; Carbon Isotopes; Female; Humans; Isotope Labeling; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnant Women; Tyrosine | 2020 |
Guide for diagnosis and treatment of hyperphenylalaninemia.
Topics: Biopterins; Female; Humans; Japan; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2021 |
Sapropterin for phenylketonuria: A Japanese post-marketing surveillance study.
Topics: Biopterins; Child, Preschool; Female; Humans; Japan; Male; Phenylalanine; Phenylketonurias; Pregnancy; Product Surveillance, Postmarketing | 2022 |
Maternal BMI and Glycemia Impact the Fetal Metabolome.
Topics: 3-Hydroxybutyric Acid; Adiposity; Adult; Amino Acids, Branched-Chain; Birth Weight; Blood Glucose; Body Mass Index; Cohort Studies; Diabetes Mellitus, Type 2; Ethnicity; Female; Fetal Blood; Fetus; Glucose Tolerance Test; Humans; Infant, Newborn; Insulin Resistance; Linear Models; Male; Meta-Analysis as Topic; Metabolome; Metabolomics; Obesity; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Triglycerides; Young Adult | 2017 |
Effect of Blood Phenylalanine Levels on Oxidative Stress in Classical Phenylketonuric Patients.
Topics: Case-Control Studies; Female; Humans; Oxidative Stress; Phenylalanine; Phenylketonurias; Pregnancy | 2018 |
Lysine Requirements of Healthy Pregnant Women are Higher During Late Stages of Gestation Compared to Early Gestation.
Topics: Adolescent; Adult; Blood Glucose; Body Composition; Body Mass Index; Diet; Dietary Proteins; Energy Metabolism; Female; Humans; Lysine; Maternal Nutritional Physiological Phenomena; Phenylalanine; Pregnancy; Pregnancy Trimesters; Recommended Dietary Allowances; Time Factors; Young Adult | 2018 |
Detection and scavenging of hydroxyl radical via D-phenylalanine hydroxylation in human fluids.
Topics: Adult; Chocolate; Diet; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Iron; Male; Middle Aged; Milk, Human; Phenylalanine; Pregnancy; Reproducibility of Results; Semen; Thiourea; Tyrosine; Young Adult | 2018 |
Successful control of maternal phenylketonuria by tetrahydrobiopterin.
Topics: Adult; Biopterins; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 2018 |
Hematological and biochemical parameters of dairy calves submitted to pegbovigrastim administration.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Body Weight; Brazil; Cattle; Female; Leukocyte Count; Neutrophils; Phenylalanine; Pregnancy | 2019 |
RNA-Seq analysis in an avian model of maternal phenylketonuria.
Topics: Animals; Chickens; Disease Models, Animal; Female; Heart Defects, Congenital; Metabolic Networks and Pathways; Phenotype; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Sequence Analysis, RNA; Transcriptome; Tretinoin; Zygote | 2019 |
Phenylalanine and tyrosine measurements across gestation by tandem mass spectrometer on dried blood spot cards from normal pregnant women.
Topics: Dried Blood Spot Testing; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Reference Values; Tandem Mass Spectrometry; Tyrosine; Young Adult | 2019 |
RHD del28Phe (DMW) encoded by a novel in-frame deletion resulting in reduced D antigen expression.
Topics: Alleles; Down-Regulation; Female; Gene Expression; Genotype; Humans; Infant, Newborn; Phenotype; Phenylalanine; Pregnancy; Rh-Hr Blood-Group System; Sequence Deletion; White People | 2019 |
Novel high-coverage targeted metabolomics method (SWATHtoMRM) for exploring follicular fluid metabolome alterations in women with recurrent spontaneous abortion undergoing in vitro fertilization.
Topics: Abortion, Habitual; Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Down-Regulation; Female; Fertilization in Vitro; Follicular Fluid; Humans; Mass Spectrometry; Metabolome; Metabolomics; Phenylalanine; Pregnancy; Up-Regulation | 2019 |
Noninvasive metabolomic profiling of human embryo culture media using a simple spectroscopy adjunct to morphology for embryo assessment in in vitro fertilization (IVF).
Topics: Adult; Albumins; Culture Media; Embryo Culture Techniques; Embryo, Mammalian; Female; Fertilization in Vitro; Humans; Metabolomics; Phenylalanine; Pregnancy; Pyruvates; Reproducibility of Results; Spectrum Analysis, Raman | 2013 |
Maternal hyperphenylalaninemia: rapid achievement of metabolic control predicts overall control throughout pregnancy.
Topics: Adult; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Pregnancy Complications; Retrospective Studies | 2013 |
Maternal Phenylketonuria International Collaborative Study revisited: evaluation of maternal nutritional risk factors besides phenylalanine for fetal congenital heart defects.
Topics: Amino Acids; Body Weight; Dietary Proteins; Female; Folic Acid; Heart Defects, Congenital; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, First; Registries; Risk Factors; Weight Gain | 2014 |
Pregnancy in an NTBC-treated patient with hereditary tyrosinemia type I.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Combined Modality Therapy; Contraindications; Cyclohexanones; Enzyme Inhibitors; Female; Humans; Nitrobenzoates; Phenylalanine; Pregnancy; Pregnancy Complications; Term Birth; Tyrosine; Tyrosinemias | 2015 |
Breastfeeding infants with phenylketonuria in the United States and Canada.
Topics: Breast Feeding; Canada; Child Development; Female; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Infant, Newborn; Male; Milk, Human; Mothers; Phenylalanine; Phenylketonurias; Pregnancy; Surveys and Questionnaires; Time Factors; United States; Weaning | 2014 |
Case report: prenatal diagnosis of Hb Hammersmith [β42(CD1)Phe→Ser; HBB: c.128T > C] in a family with an adult male patient.
Topics: Adult; Anemia, Hemolytic; Base Sequence; beta-Globins; Child, Preschool; Cyanosis; DNA Mutational Analysis; Family Health; Female; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Male; Mutation, Missense; Phenylalanine; Pregnancy; Prenatal Diagnosis; Serine; Splenomegaly | 2014 |
Sapropterin dihydrochloride use in pregnant women with phenylketonuria: an interim report of the PKU MOMS sub-registry.
Topics: Abortion, Spontaneous; Adult; Biopterins; Female; Humans; Obstetric Labor, Premature; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Young Adult | 2014 |
Metalloprotease dependent release of placenta derived fractalkine.
Topics: Adult; Cell Line; Cell Membrane; Chemokine CX3CL1; Female; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Inflammation; Metalloproteases; Microvilli; Phenylalanine; Placenta; Pregnancy; Pregnancy Trimester, First; Thiophenes; Trophoblasts | 2014 |
Use of sapropterin dihydrochloride in maternal phenylketonuria. A European experience of eight cases.
Topics: Adult; Biopterins; Europe; Female; Fetal Blood; Genotype; Humans; Infant, Newborn; Nutritional Status; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pterins | 2014 |
The immunologic and antioxidant effects of L-phenylalanine on the uterine implantation of mice embryos during early pregnancy.
Topics: Animals; Antioxidants; Cell Proliferation; Cytokines; Embryo Implantation; Embryonic Development; Female; Lipid Peroxides; Lymphocytes; Mice; Mice, Inbred ICR; Phenylalanine; Pregnancy; Pregnancy, Animal; Uterus | 2014 |
Cystinuria in a girl presenting with a hyperechogenic colon detected by prenatal ultrasonography and a new SLC3A1 gene mutation (p.Phe278Ser).
Topics: Adult; Alleles; Amino Acid Substitution; Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Colon; Consanguinity; Cystinuria; DNA Mutational Analysis; Exons; Female; Homozygote; Humans; Infant; Infant, Newborn; Kidney; Kidney Calculi; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Serine; Ultrasonography, Prenatal | 2014 |
Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of energy metabolism in cerebral cortex and hippocampus of the offspring.
Topics: Animals; Cerebral Cortex; Creatine; Drug Therapy, Combination; Energy Metabolism; Female; Hippocampus; Lactation; Phenylalanine; Pregnancy; Pyruvic Acid; Random Allocation; Rats; Rats, Wistar | 2014 |
Effects of phenylalanine on reproductive performance and teratogenesis in mice.
Topics: Animals; Cyclophosphamide; Female; Male; Mice; Organ Size; Phenylalanine; Pregnancy; Pregnancy Outcome; Reproduction; Teratogenesis; Teratogens; Uterus | 2014 |
Tryptophan requirement of pregnant sows.
Topics: Age Factors; Animals; Biomarkers; Body Weight; Calorimetry, Indirect; Carbon Isotopes; Diet; Energy Metabolism; Female; Kinetics; Linear Models; Nutritional Requirements; Parity; Phenylalanine; Pregnancy; Swine; Tryptophan | 2014 |
Diagnostic and management practices for phenylketonuria in 19 countries of the South and Eastern European Region: survey results.
Topics: Adolescent; Adult; Child; Child, Preschool; Disease Management; Europe; Female; Health Personnel; Humans; Infant; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Pregnancy; Surveys and Questionnaires; Young Adult | 2016 |
The challenges of managing coexistent disorders with phenylketonuria: 30 cases.
Topics: Adolescent; Adult; Autoimmune Diseases; Biopterins; Child; Child, Preschool; Chromosome Aberrations; Consanguinity; Diet; Disease Management; Europe; Female; Gastrointestinal Diseases; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Pregnancy; Retrospective Studies; Turkey | 2015 |
Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation.
Topics: Biological Transport; Carbon Radioisotopes; Creatinine; Female; Humans; Maternal-Fetal Exchange; Models, Biological; Perfusion; Phenylalanine; Placenta; Pregnancy | 2016 |
Founder effect is responsible for the p.Leu131Phe heparin-binding-site antithrombin mutation common in Hungary: phenotype analysis in a large cohort.
Topics: Adolescent; Adult; Aged; Antithrombins; Arteries; Binding Sites; Child; Child, Preschool; Cohort Studies; Factor Xa; Female; Founder Effect; Genetic Association Studies; Heparin; Heterozygote; Humans; Hungary; Leucine; Microsatellite Repeats; Middle Aged; Mutation; Phenotype; Phenylalanine; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Sensitivity and Specificity; Thrombosis; Young Adult | 2016 |
[Maternal phenylketonuria: the challenge of the second generation].
Topics: Craniofacial Abnormalities; Female; France; Humans; Infant, Newborn; Musculoskeletal Abnormalities; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Psychomotor Disorders | 2008 |
Factors influencing outcomes in the offspring of mothers with phenylketonuria during pregnancy: the importance of variation in maternal blood phenylalanine.
Topics: Body Weight; Developmental Disabilities; Female; Humans; Infant, Newborn; Learning Disabilities; Microcephaly; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Retrospective Studies; Treatment Outcome | 2008 |
The effect of the mode of delivery on maternal-neonatal interleukin-6, biogenic amine and their precursor amino acid concentrations.
Topics: Adult; Amino Acids, Aromatic; Antioxidants; Biogenic Amines; Blood Pressure; Catecholamines; Cesarean Section; Creatine Kinase; Delivery, Obstetric; Female; Fetal Blood; Heart Rate; Humans; Infant, Newborn; Interleukin-6; Lipids; Liver; Natural Childbirth; Phenylalanine; Pregnancy; Serotonin; Tryptophan; Tyrosine; Young Adult | 2008 |
Human fetal amino acid metabolism at term gestation.
Topics: Adult; Blood Flow Velocity; Carbon Isotopes; Cesarean Section; Female; Fetal Blood; Fetal Proteins; Fetus; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Hydroxylation; Infant; Infant, Newborn; Male; Nutritional Requirements; Phenylalanine; Pregnancy; Prenatal Nutritional Physiological Phenomena; Regional Blood Flow; Tyrosine; Ultrasonography | 2009 |
Phenylalanine tolerance in three phenylketonuric women pregnant with fetuses of different genetic PKU status.
Topics: Adult; Birth Weight; Female; Fetus; Genotype; Heterozygote; Homozygote; Humans; Infant, Newborn; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Pregnancy; Weight Gain | 2009 |
[Classic maternal phenylketonuria and sonographic evidence of fetal trisomy 21: first description].
Topics: Adult; Down Syndrome; Female; Humans; Hydrothorax; Infant, Newborn; Karyotyping; Male; Obstetric Labor, Premature; Phenylalanine; Phenylketonurias; Polyhydramnios; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Prenatal Care; Ultrasonography, Prenatal | 2009 |
[Did the change of technique of screening investigations influence on improvement of test credibility in recognizing and differentiating diagnostics of hiperphenylalaninemias?].
Topics: Adult; Colorimetry; Female; Humans; Infant; Infant, Newborn; Male; Mass Screening; Neonatal Screening; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Poland; Pregnancy; Prevalence | 2009 |
Maternal phenylketonuria.
Topics: Child; Epilepsy; Female; Humans; Infant; Male; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Prenatal Exposure Delayed Effects | 2009 |
A case of maternal PKU syndrome despite intensive patient counseling.
Topics: Diet, Protein-Restricted; Female; Fetal Growth Retardation; Genetic Counseling; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Patient Compliance; Patient Education as Topic; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Ultrasonography, Prenatal; Young Adult | 2009 |
A case of maternal phenylketonuria syndrome presenting with unilateral renal agenesis.
Topics: Congenital Abnormalities; Diagnosis, Differential; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Kidney; Kidney Diseases; Microcephaly; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Radionuclide Imaging; Syndrome; Tomography, X-Ray Computed; Ultrasonography; Young Adult | 2011 |
GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase.
Topics: B7 Antigens; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Membrane; Collagen; Enzyme Activation; Female; Gene Library; Humans; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Phenylalanine; Placenta; Pregnancy; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Thiophenes; Transfection | 2010 |
Determination of unconjugated aromatic acids in urine by capillary electrophoresis with dual electrochemical detection--potential application in fast diagnosis of phenylketonuria.
Topics: Adult; Biomarkers; Electrodes; Electrophoresis, Capillary; Female; Humans; Hydrogen-Ion Concentration; Infant; Linear Models; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2010 |
Dietary treatment of phenylketonuria: the effect of phenylalanine on reaction time.
Topics: Adult; Case-Control Studies; Cognition; Diet; Female; Humans; Male; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Preconception Care; Pregnancy; Quality of Life; Reaction Time; Saccades | 2011 |
Retrospective, observational data collection of the treatment of phenylketonuria in the UK, and associated clinical and health outcomes.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Data Collection; Female; Humans; Infant; Infant, Newborn; Patient Compliance; Phenylalanine; Phenylketonurias; Pregnancy; Retrospective Studies; Sex Factors; Treatment Outcome; United Kingdom | 2011 |
Netrin-1-induced local β-actin synthesis and growth cone guidance requires zipcode binding protein 1.
Topics: Actinin; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cell Movement; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Female; Gene Expression Regulation; Green Fluorescent Proteins; Growth Cones; Male; Mice; Mice, Knockout; Mutation; Nerve Growth Factors; Netrin-1; Neurons; Phenylalanine; Pregnancy; Pseudopodia; Rats; Rats, Sprague-Dawley; RNA, Messenger; Statistics, Nonparametric; Time Factors; Transfection; Tumor Suppressor Proteins; Tyrosine | 2011 |
First-trimester prediction of preeclampsia using metabolomic biomarkers: a discovery phase study.
Topics: Adult; Alanine; Area Under Curve; Biomarkers; Carnitine; Case-Control Studies; Female; Gestational Age; Glutamic Acid; Humans; Metabolomics; Phenylalanine; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Reproducibility of Results | 2011 |
Effect of vinyl sulfone inhibitors of cysteine proteinases on Tritrichomonas foetus infection.
Topics: Animals; Apoptosis; Coculture Techniques; Cysteine Proteases; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Female; Genital Diseases, Female; Mice; Mice, Inbred BALB C; Models, Animal; Oligopeptides; Parasitic Sensitivity Tests; Phenylalanine; Piperazines; Pregnancy; Pregnancy Complications, Parasitic; Sulfones; Tosyl Compounds; Trichomonas Infections; Tritrichomonas foetus; Trophoblasts; Trophozoites; Vinyl Compounds | 2012 |
Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes.
Topics: Boron Compounds; Chromatography, High Pressure Liquid; Cryptorchidism; Endocrine Disruptors; Environmental Exposure; Female; Fetal Blood; Humans; Infant, Newborn; Male; Mass Spectrometry; Milk, Human; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Testosterone | 2012 |
Maternal phenylketonuria: low phenylalaninemia might increase the risk of intra uterine growth retardation.
Topics: Diet, Protein-Restricted; Female; Fetal Growth Retardation; France; Humans; Infant, Newborn; Phenylalanine; Phenylketonuria, Maternal; Practice Guidelines as Topic; Pregnancy; Pregnancy Outcome; Retrospective Studies; Risk Factors | 2012 |
Cardiac teratogenicity in mouse maternal phenylketonuria: defining phenotype parameters and genetic background influences.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Genetic Association Studies; Heart Defects, Congenital; Heart Valves; Humans; Male; Mice; Mice, Transgenic; Phenotype; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 2012 |
The role of amino acids in spina bifida.
Topics: Adult; Alanine; Amino Acids; Amniocentesis; Amniotic Fluid; Cystathionine; Cysteine; Female; Gestational Age; Humans; Phenylalanine; Pregnancy; Pregnancy Trimester, Second; Spinal Dysraphism; Tryptophan; Tyrosine; Ultrasonography, Prenatal | 2012 |
Growth parameters in newborns with hyperphenylalaninaemia.
Topics: Birth Weight; Body Height; Case-Control Studies; Cephalometry; Female; Fetal Growth Retardation; Gestational Age; Humans; Infant, Newborn; Italy; Male; Phenylalanine; Phenylketonurias; Pregnancy | 2002 |
Oxidative stress induced by phenylketonuria in the rat: Prevention by melatonin, vitamin E, and vitamin C.
Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Brain; Cerebellum; Disease Models, Animal; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Lipid Peroxidation; Melatonin; Nervous System Malformations; Neurons; Oxidative Stress; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Vitamin E | 2002 |
Protein anabolic effects of insulin and IGF-I in the ovine fetus.
Topics: Albumins; Animals; Blood Glucose; Energy Metabolism; Female; Fetus; Glucose; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Muscle, Skeletal; Oxygen; Phenylalanine; Pregnancy; Sheep | 2003 |
Simultaneous measurement of phenylalanine and tyrosine in phenylketonuric plasma and dried blood by high-performance liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Female; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tyrosine | 2003 |
Maternal phenylketonuria in Western Australia: pregnancy outcomes and developmental outcomes in offspring.
Topics: Child Behavior; Child Development; Child, Preschool; Cognition; Developmental Disabilities; Female; Hospitals, Maternity; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Risk Factors; Western Australia | 2003 |
Uptake of C-14-para-fluorophenylalanine in the tissues of mice.
Topics: Amino Acids; Animals; Biochemical Phenomena; Female; Mice; p-Fluorophenylalanine; Phenylalanine; Pregnancy | 1962 |
INFLUENCE OF EXCESS DIETARY PHENYLALANINE ON PREGNANT RATS AND THEIR FETUSES.
Topics: Animals; Blood Chemical Analysis; Female; Fetus; Humans; Maternal-Fetal Exchange; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Pregnancy; Pregnancy, Animal; Rats; Research; Tyrosine | 1964 |
[OCTAPRESSIN FOR LOCAL APPLICATION (INFILTRATION) IN OBSTETRICS AND GYNECOLOGY (1ST EXPERIENCES)].
Topics: Biomedical Research; Episiotomy; Felypressin; Female; Gynecology; Hemostatics; Humans; Leiomyoma; Obstetric Labor Complications; Obstetrics; Perineum; Phenylalanine; Pregnancy; Surgical Procedures, Operative; Toxicology; Uterine Neoplasms; Vasopressins | 1964 |
[SEX-SPECIFIC DIFFERENCES OF SERUM AMINO ACID CONCENTRATIONS].
Topics: Amino Acids; Biomedical Research; Blood; Chromatography; Cystine; Isoleucine; Leucine; Phenylalanine; Pregnancy; Sex; Tyrosine; Valine | 1965 |
Impact of the phenylalanine hydroxylase gene on maternal phenylketonuria outcome.
Topics: Analysis of Variance; Child; Cognition; Female; Genotype; Humans; Intelligence; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Regression Analysis | 2003 |
Role of nutrition in pregnancy with phenylketonuria and birth defects.
Topics: Female; Heart Defects, Congenital; Humans; Infant, Newborn; Logistic Models; Microcephaly; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prenatal Care; Prospective Studies; Weight Gain | 2003 |
Relation of prenatal phenylalanine exposure to infant and childhood cognitive outcomes: results from the International Maternal PKU Collaborative Study.
Topics: Aptitude Tests; Child; Child Development; Child, Preschool; Female; Humans; Infant, Newborn; Intellectual Disability; Intelligence; Linear Models; Longitudinal Studies; Male; Models, Statistical; Mutation; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Socioeconomic Factors | 2003 |
Cognitive and behavioral development in maternal phenylketonuria offspring.
Topics: Analysis of Variance; Case-Control Studies; Child; Child Behavior; Child Behavior Disorders; Child Development; Cognition; Female; Humans; Intellectual Disability; Intelligence; Logistic Models; Longitudinal Studies; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Psychological Tests; Socioeconomic Factors; Statistics, Nonparametric | 2003 |
Pregnancy experiences in the woman with mild hyperphenylalaninemia.
Topics: Birth Weight; Body Height; Case-Control Studies; Female; Head; Humans; Infant; Infant, Newborn; Intelligence; Intelligence Tests; Mutation; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Pregnancy Complications; Reference Values | 2003 |
Maternal phenylketonuria: experiences from the United Kingdom.
Topics: Birth Weight; Child; Child, Preschool; Cohort Studies; Diet, Protein-Restricted; Female; Head; Humans; Infant; Infant, Newborn; Intelligence; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Preconception Care; Pregnancy; Prenatal Care; Registries; United Kingdom | 2003 |
Potential role of tetrahydrobiopterin in the treatment of maternal phenylketonuria.
Topics: Biopterins; Child, Preschool; Diet, Protein-Restricted; Female; Follow-Up Studies; Genotype; Humans; Infant, Newborn; Male; Mutation; Neonatal Screening; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2003 |
Developmental timing of exposure to elevated levels of phenylalanine is associated with ADHD symptom expression.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Female; Follow-Up Studies; Humans; Male; Mothers; Phenylalanine; Phenylketonurias; Pregnancy; Prospective Studies; Time Factors | 2003 |
Effect of high maternal blood phenylalanine on offspring congenital anomalies and developmental outcome at ages 4 and 6 years: the importance of strict dietary control preconception and throughout pregnancy.
Topics: Abnormalities, Multiple; Child; Child, Preschool; Cognition; Developmental Disabilities; Diet, Protein-Restricted; Face; Female; Fetal Growth Retardation; Gestational Age; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Intelligence Tests; Microcephaly; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Prenatal Care | 2004 |
Different embryo-fetal toxicity effects for three VLA-4 antagonists.
Topics: Abnormalities, Drug-Induced; Animals; Benzene Derivatives; Cell Communication; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Embryo, Mammalian; Embryonic Development; Female; Homozygote; Imidazoles; Integrin alpha4beta1; Maternal Exposure; Maternal-Fetal Exchange; Mice; Models, Chemical; Phenylalanine; Phenylurea Compounds; Pregnancy; Pregnancy, Animal; Propionates; Rabbits; Rats; Species Specificity; Teratogens | 2004 |
Critical period for a teratogenic VLA-4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Area Under Curve; Benzene Derivatives; Cell Adhesion; Cell Line; Chorion; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Embryo, Mammalian; Embryonic Development; Female; Heart; Humans; Imidazoles; Inhibitory Concentration 50; Integrin alpha4beta1; Maternal Exposure; Maternal-Fetal Exchange; Models, Chemical; Phenylalanine; Phenylurea Compounds; Pregnancy; Pregnancy, Animal; Propionates; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Very Late Antigen; Species Specificity; Teratogens; Time Factors | 2004 |
High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons.
Topics: Age Factors; Animals; Animals, Newborn; Blotting, Western; Bromodeoxyuridine; Cell Line; Cerebral Cortex; DNA-Binding Proteins; Embryo, Mammalian; Female; Glutamic Acid; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Kidney; LDL-Receptor Related Proteins; Male; Mice; Mice, Mutant Strains; Nerve Tissue Proteins; Neurons; Neuropeptides; Phenylalanine; POU Domain Factors; Precipitin Tests; Pregnancy; Receptors, Cell Surface; Receptors, LDL; Receptors, Lipoprotein; Reelin Protein; Staining and Labeling; T-Box Domain Proteins; Trans-Activators; Valine | 2004 |
Learning and behavioural difficulties but not microcephaly in three brothers resulting from undiagnosed maternal phenylketonuria.
Topics: Adult; Child; Child Behavior Disorders; Female; Humans; Learning Disabilities; Male; Pedigree; Phenotype; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 2004 |
Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.
Topics: 5-Hydroxytryptophan; Axons; Biopterins; Brain Damage, Chronic; Cerebral Cortex; Child; Child, Preschool; Combined Modality Therapy; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence; Levodopa; Male; Neonatal Screening; Nerve Fibers, Myelinated; Phenylalanine; Phenylketonurias; Pregnancy | 2004 |
Tyr204Phe and Val34Leu polymorphisms in two Brazilian ethnic groups and in patients with recurrent miscarriages.
Topics: Abortion, Habitual; Black People; Brazil; Factor XIII; Female; Humans; Leucine; Male; Phenylalanine; Polymorphism, Genetic; Pregnancy; Tyrosine; Valine; White People | 2004 |
Role of phenylalanine 20 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Animals; Cell Culture Techniques; Copper; Female; Mitochondria; Molecular Sequence Data; Neurons; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Phenylalanine; Point Mutation; Pregnancy; Rats; Time Factors | 2004 |
Proteasome activity is altered in skeletal muscle tissue of tumour-bearing rats a leucine-rich diet.
Topics: Animals; Carcinoma 256, Walker; Dietary Supplements; Electrophoresis, Polyacrylamide Gel; Female; Leucine; Muscle, Skeletal; Myosin Heavy Chains; Phenylalanine; Pregnancy; Pregnancy Complications, Neoplastic; Proteasome Endopeptidase Complex; Protein Biosynthesis; Rats; Rats, Wistar; Tumor Cells, Cultured; Tyrosine; Ubiquitin | 2004 |
Maternal phenylketonuria: report from the United Kingdom Registry 1978-97.
Topics: Analysis of Variance; Birth Weight; Child; Child, Preschool; Cognition Disorders; Developmental Disabilities; Female; Head; Heart Defects, Congenital; Humans; Infant, Newborn; Intelligence; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Registries; Time Factors; United Kingdom | 2005 |
Maternal phenylketonuria: a case study suggesting the use of prenatal psychotherapy to help control phenylalanine levels.
Topics: Adult; Cognitive Behavioral Therapy; Depression; Female; Humans; Mothers; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Care; Surveys and Questionnaires | 2002 |
Amniotic fluid amino acid concentrations are modified by maternal dietary glucose, gestational age, and fetal growth in rats.
Topics: Amino Acids; Amniotic Fluid; Animals; Diet; Female; Fetal Development; Gestational Age; Glucose; Methionine; Osmolar Concentration; Phenylalanine; Predictive Value of Tests; Pregnancy; Pregnancy, Animal; Rats; Taurine | 2005 |
Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.
Topics: Aldehydes; Animals; Animals, Newborn; Ascorbic Acid; Disease Models, Animal; Drug Interactions; Female; Male; Malondialdehyde; Melatonin; Mitochondrial Diseases; Phenethylamines; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Time Factors; Vitamin A | 2006 |
Tetrahydrobiopterin and maternal PKU.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Biopterins; Combined Modality Therapy; Diet, Protein-Restricted; Female; Humans; Infant, Newborn; Mutation; Neonatal Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 2005 |
The influence of modification at position 2 on the side-chain conformation in oxytocin analogs.
Topics: Biochemistry; Chemistry, Pharmaceutical; Female; Humans; Models, Chemical; Molecular Conformation; Oxytocics; Oxytocin; Phenylalanine; Pregnancy; Premature Birth; Solvents; Stereoisomerism | 2006 |
Effect of N-benzoyl-D-phenylalanine and metformin on insulin receptors in neonatal streptozotocin-induced diabetic rats: studies on insulin binding to erythrocytes.
Topics: Animals; Animals, Newborn; Binding, Competitive; Blood Glucose; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Female; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Metformin; Phenylalanine; Pregnancy; Protein Binding; Rats; Rats, Wistar; Receptor, Insulin; Streptozocin | 2006 |
[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress].
Topics: Aging; Analgesics; Animals; Female; Inflammation; Male; Ondansetron; Pain; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Stress, Physiological | 2007 |
Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity.
Topics: Amino Acid Substitution; Animals; Cell Line; Cells, Cultured; DNA, Complementary; Embryo, Mammalian; Enzyme Activation; Female; Fibroblasts; Humans; Janus Kinase 2; Kidney; Models, Biological; Phenylalanine; Phosphorylation; Plasmids; Pregnancy; Protein Structure, Tertiary; Receptors, Erythropoietin; Retroviridae; Transfection | 2008 |
Neuropathology of a 4-month-old infant born to a woman with phenylketonuria.
Topics: Adult; Agenesis of Corpus Callosum; Biopsy; Cerebrosides; Fatal Outcome; Female; Heart Failure; Humans; Infant; Magnetic Resonance Imaging; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prosencephalon; Sulfoglycosphingolipids | 2008 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Children of phenylketonuric mothers.
Topics: Female; Humans; Infant, Newborn; Intellectual Disability; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic | 1967 |
Biopterin and folic acid deficiency.
Topics: Anemia, Macrocytic; Animals; Blood Protein Electrophoresis; Chick Embryo; Diet; Female; Folic Acid Deficiency; Hemoglobins; Humans; Phenylalanine; Pregnancy; Pregnancy Complications, Hematologic; Pteridines; Reticulocytes; Vitamin B 12 | 1967 |
Congenital malformations in offspring of phenylketonuric mothers.
Topics: Abortion, Habitual; Adult; Birth Weight; Child; Child, Preschool; Congenital Abnormalities; Female; Heart Defects, Congenital; Hip Dislocation, Congenital; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic; Strabismus | 1967 |
Role of hyperphenylalaninemia in pregnant women as a cause of mental retardation in offspring.
Topics: Diet Therapy; Dietary Proteins; Female; Humans; Intellectual Disability; Phenylalanine; Pregnancy; Pregnancy Complications | 1967 |
Phenylketonuria.
Topics: Diet Therapy; Dietary Proteins; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Intelligence; Intelligence Tests; Male; Mass Screening; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1967 |
Hypervalinemia. A defect in valine transamination.
Topics: Amino Acid Metabolism, Inborn Errors; Asian People; Carbon Isotopes; Child, Preschool; Female; Fetal Diseases; Humans; Intellectual Disability; Isoleucine; Japan; Keto Acids; Leucine; Leukocytes; Methionine; Phenylalanine; Placenta; Pregnancy; Transaminases; Valine | 1967 |
Dietary induction of hyperphenylalaninemia in the rat.
Topics: Animals; Body Weight; Diet; Female; Growth; Humans; Liver; Mortality; Oxidoreductases; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy, Animal; Rats; Tryptophan; Tyrosine | 1967 |
Low-phenylalanine diets for pregnant PKU heterozygotes are unnecessary.
Topics: Diet; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Care | 1967 |
Co-trimoxazole and phenylalanine metabolism.
Topics: Child; Drug Synergism; Female; Humans; Phenylalanine; Pregnancy; Sulfamethoxazole; Trimethoprim | 1980 |
Phenylacetate and brain dysfunction in experimental phenylketonuria: synaptic development.
Topics: Animals; Cerebral Cortex; Choline; Female; Fenclonine; gamma-Aminobutyric Acid; Humans; Male; Neurotransmitter Agents; Norepinephrine; Organ Size; Phenethylamines; Phenylacetates; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Serotonin; Sialic Acids; Synaptosomes | 1980 |
Neurotransmitter defects and treatment of disorders of hyperphenylalaninemia.
Topics: Brain; Child; Child, Preschool; Dihydropteridine Reductase; Female; Humans; Infant; Infant, Newborn; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pregnancy | 1981 |
Modulation of amino acid transport in preimplantation mouse embryos by low concentrations of non-ionic and zwitterionic detergents.
Topics: Amino Acids; Animals; Biological Transport, Active; Blastocyst; Cleavage Stage, Ovum; Detergents; Female; Glucosides; Glutamates; Glutamic Acid; Leucine; Methionine; Mice; Octoxynol; Phenylalanine; Polyethylene Glycols; Pregnancy; Quaternary Ammonium Compounds; Surface-Active Agents | 1984 |
Synthesis of first trimester placental alkaline phosphatase in cultured human term placental cells.
Topics: Alkaline Phosphatase; Cell Line; Cell Transformation, Viral; Dactinomycin; DNA; Female; Homoarginine; Humans; Kinetics; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Pregnancy Trimester, First; Protein Biosynthesis; RNA; Temperature | 1980 |
Alkaline phosphatase in hematopoietic tumor cell lines of the mouse: high activity in cells of the B lymphoid lineage.
Topics: Alkaline Phosphatase; Animals; B-Lymphocytes; Cell Line; Cell Membrane; Female; Hematopoietic Stem Cells; Homoarginine; Hydrogen-Ion Concentration; Kidney; Mice; Neoplasms, Experimental; Phenylalanine; Placenta; Pregnancy | 1981 |
[Shift of placental alkaline phosphatase isoenzymes in the course of pregnancy].
Topics: Alkaline Phosphatase; Chorionic Gonadotropin; Female; Homoarginine; Hot Temperature; Humans; Isoenzymes; Leucine; Phenylalanine; Placenta; Pregnancy; Pregnancy Proteins | 1984 |
A study of placental transfer mechanisms in nonhuman primates using [14C]phenylalanine.
Topics: Animals; Carbon Radioisotopes; Female; Fenclonine; Fetal Blood; Macaca fascicularis; Macaca mulatta; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Tyrosine | 1982 |
Placental transfer of aromatic amino acids in non-human primates.
Topics: Amino Acids; Amniotic Fluid; Animals; Female; Fenclonine; Fetal Blood; Macaca fascicularis; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy | 1983 |
Analysis of learning in retarded monkeys.
Topics: Animals; Attention; Concept Formation; Discrimination, Psychological; Disease Models, Animal; Female; Fenclonine; Humans; Learning; Macaca mulatta; Phenylalanine; Phenylketonurias; Pregnancy; Reinforcement, Psychology; Retention, Psychology | 1984 |
Placental transfer of phenylalanine in Macaca mulatta and Macaca fascicularis.
Topics: Animals; Female; Fenclonine; Fetal Blood; Macaca; Macaca fascicularis; Macaca mulatta; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy | 1983 |
Dietary and metabolic effects on rhesus social behavior: phenylalanine-related dietary alterations.
Topics: Aggression; Animals; Female; Fenclonine; Haplorhini; Humans; Macaca mulatta; Phenylalanine; Phenylketonurias; Play and Playthings; Pregnancy; Social Behavior | 1980 |
Phenylacetate and the enduring behavioral deficit in experimental phenylketonuria.
Topics: Animals; Behavior, Animal; Body Weight; Escape Reaction; Female; Fenclonine; Humans; Hyperkinesis; Male; Phenethylamines; Phenylacetates; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Sex Factors | 1980 |
More on untreated maternal hyperphenylalaninemia.
Topics: Child; Female; Humans; Intelligence; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1984 |
Ochratoxin A-induced teratogenesis in rats: partial protection by phenylalanine.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Female; Ochratoxins; Phenylalanine; Pregnancy; Rats; Rats, Inbred Strains | 1984 |
Protein synthesis in rat tissues during lactation. No effect of diethyl ether anaesthesia.
Topics: Anesthesia, Inhalation; Animals; Cattle; Ether; Ethyl Ethers; Female; Intestinal Mucosa; Lactation; Liver; Mammary Glands, Animal; Muscles; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats | 1984 |
Maternal phenylketonuria.
Topics: Adolescent; Adult; Child; Female; Genetic Counseling; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy | 1984 |
Newly established uterine cervical cancer cell line (SKG-III) with Regan isoenzyme, human chorionic gonadotropin beta-subunit, and pregnancy-specific beta 1-glycoprotein phenotypes.
Topics: Alkaline Phosphatase; Cell Line; Chorionic Gonadotropin; Female; Hot Temperature; Humans; Isoenzymes; Leucine; Levamisole; Liver; Microscopy, Electron; Phenylalanine; Placenta; Pregnancy; Pregnancy Proteins; Pregnancy-Specific beta 1-Glycoproteins; Radioimmunoassay; Uterine Cervical Neoplasms | 1983 |
Effects of untreated maternal phenylketonuria and hyperphenylalaninemia on the fetus.
Topics: Abortion, Spontaneous; Birth Weight; Body Weight; Child; Child, Preschool; Congenital Abnormalities; Female; Fetal Blood; Fetus; Humans; Infant; Infant, Newborn; Intellectual Disability; Intelligence; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1983 |
Iron deficiency in the rat: biochemical studies of fetal metabolism.
Topics: Animals; Diet; Female; Fetal Blood; Fetus; Iron Deficiencies; Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Rats; Rats, Inbred Strains; Tyrosine | 1983 |
[Effects of maltose infusion on amino acid composition of maternal venous blood and fetal blood in utero].
Topics: Adult; Amino Acids; Aspartic Acid; Blood Glucose; Female; Fetal Blood; Humans; Infusions, Parenteral; Maltose; Maternal-Fetal Exchange; Phenylalanine; Pregnancy | 1983 |
Maternal hyperphenylalaninemia fetal effects.
Topics: Adolescent; Adult; Child; Congenital Abnormalities; Face; Female; Fetal Growth Retardation; Growth Disorders; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Microcephaly; Phenylalanine; Pregnancy; Pregnancy Complications; Strabismus | 1984 |
[Maternal phenylketonuria].
Topics: Child; Chromatography, Thin Layer; Female; Heterozygote; Humans; Infant, Newborn; Intellectual Disability; Male; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1984 |
Effects of untreated maternal phenylketonuria and hyperphenylalaninemia on the fetus.
Topics: Female; Fetus; Humans; Intelligence; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1984 |
Results of screening for phenylalanine and other amino acid disturbances among pregnant women.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Female; Humans; Male; Pedigree; Phenylalanine; Pregnancy; Pregnancy Complications; Tyrosine | 1980 |
Four cases of hyperphenylalaninaemia: studies during pregnancy and of the offspring produced.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Diet; Electroencephalography; Female; Humans; Infant, Newborn; Middle Aged; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Proteins; Time Factors | 1982 |
Sensitive fluorometry of heat-stable alkaline phosphatase (Regan enzyme) activity in serum from smokers and nonsmokers.
Topics: Alkaline Phosphatase; Bone Neoplasms; Enzyme Activation; Female; Fluorometry; Hot Temperature; Humans; Phenylalanine; Pregnancy; Smoking | 1983 |
Protein synthesis in the cultured fetal mouse heart: effects of deprivation of oxygen and oxidizable substrate.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Female; Guanosine Triphosphate; Heart; Mice; Myocardium; Organ Culture Techniques; Oxygen; Phenylalanine; Pregnancy; Protein Biosynthesis; Time Factors | 1983 |
Prenatal determination of dihydropteridine reductase in a normal fetus at risk for malignant hyperphenylalaninemia.
Topics: Amniotic Fluid; Clinical Enzyme Tests; Dihydropteridine Reductase; Female; Humans; NADH, NADPH Oxidoreductases; Phenylalanine; Pregnancy; Prenatal Diagnosis; Risk | 1983 |
[Hyperphenylalaninemia in 1983].
Topics: Biopterins; Female; Fetal Diseases; Humans; Infant, Newborn; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications | 1983 |
[Problems posed by maternal phenylketonuria].
Topics: Brain; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tryptophan; Tyrosine | 1983 |
Tyrosine supplementation during pregnancy in a woman with classical phenylketonuria. A case report.
Topics: Female; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1983 |
Cord-blood tyrosine levels in the full-term phenylketonuric fetus and the "justification hypothesis".
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1980 |
Effects of pregnancy and sex steroid administration on skeletal muscle metabolism in the rat.
Topics: Alanine; Animals; Estradiol; Female; Glucose; Glycerol; Insulin; Lactates; Lactic Acid; Muscles; Oxygen Consumption; Phenylalanine; Pregnancy; Pregnancy, Animal; Progesterone; Pyruvates; Pyruvic Acid; Rats | 1981 |
Uptake and asymmetric efflux of amino acids at maternal and fetal sides of placenta.
Topics: Amino Acids; Animals; Biological Transport; Female; Fetus; Guinea Pigs; Kinetics; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Radioisotope Dilution Technique; Tritium | 1981 |
American Academy of Pediatrics Committee on Genetics: New issues in newborn screening for phenylketonuria and congenital hypothyroidism.
Topics: Biopterins; Congenital Hypothyroidism; Female; Humans; Hypothyroidism; Infant, Newborn; Mass Screening; Phenylalanine; Phenylketonurias; Pregnancy; Thyroid Hormones | 1982 |
Maternal phenylketonuria--results of dietary therapy.
Topics: Adult; Female; Fetal Diseases; Heart Defects, Congenital; Humans; Infant, Newborn; Intellectual Disability; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1982 |
Normal infant born to a mother with phenylketonuria.
Topics: Adult; Child, Preschool; Female; Fetal Diseases; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First | 1982 |
Characterization and use of an allotype-specific monoclonal antibody to placental alkaline phosphatase in the study of cancer-related phosphatase polymorphism.
Topics: Alkaline Phosphatase; Alleles; Animals; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hybridomas; Kinetics; Leucine; Mice; Mice, Inbred BALB C; Neoplasms; Phenotype; Phenylalanine; Placenta; Polymorphism, Genetic; Pregnancy | 1982 |
Nutrition in pregnancy of women with hyperphenylalaninemia.
Topics: Abortion, Spontaneous; Congenital Abnormalities; Female; Fetal Death; Fetal Growth Retardation; Humans; Intellectual Disability; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1982 |
Treatment of phenylketonuria during pregnancy.
Topics: Adult; Diet; Female; Follow-Up Studies; Heart Defects, Congenital; Humans; Infant; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1982 |
A routine method for alkaline phosphatase assay in pregnancy serum.
Topics: Alkaline Phosphatase; Bone and Bones; Female; Humans; Isoenzymes; Liver; Phenylalanine; Placenta; Pregnancy; Tetramisole | 1982 |
Plasma amino acid pattern in phenylketonuric heterozygotes during pregnancy.
Topics: Adult; Amino Acids; Female; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Tyrosine | 1982 |
Transport specificity for neutral and basic amino acids at maternal and fetal interfaces of the guinea-pig placenta.
Topics: Alanine; Animals; Biological Transport; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Sodium; Stereoisomerism; Trophoblasts | 1982 |
Projections of a rebound in frequency of mental retardation from phenylketonuria.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Gene Frequency; Genetic Carrier Screening; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Mass Screening; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Care; Prognosis | 1982 |
[Maternal phenylketonuria syndrome: teratogenic effect of hyperphenylalaninemia].
Topics: Adult; Female; Fetal Growth Retardation; Genetic Counseling; Humans; Infant; Intellectual Disability; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Syndrome | 1982 |
[Congenital errors of metabolism: phenylketonuria and hyperphenylalanemias].
Topics: Diagnosis, Differential; Female; Genetic Carrier Screening; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Pregnancy | 1982 |
The effects of hyperphenylalaninemia on fetal development: a new animal model of maternal phenylketonuria.
Topics: Animals; Brain; Diet; Female; Fetus; Growth; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred F344 | 1982 |
Levels of free amino acids in lactating women following ingestion of the sweetener aspartame.
Topics: Adult; Aspartame; Dipeptides; Female; Humans; Lactation; Lactose; Phenylalanine; Pregnancy; Tyrosine | 1980 |
Unsuccessful treatment of phenylketonuria with tyrosine.
Topics: Adult; Child Development; Female; Food, Fortified; Humans; Infant, Newborn; Intellectual Disability; Intelligence Tests; Male; Neurologic Manifestations; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1981 |
Maternal influences on tryptophan hydroxylase activity in embryonic rat brain.
Topics: Animals; Brain; Cell Differentiation; Female; Hydrocortisone; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Serotonin; Stress, Physiological; Tryptophan; Tryptophan Hydroxylase | 1981 |
Outcome of pregnancy in a phenylketonuric mother after low phenylalanine diet introduced from the ninth week of pregnancy.
Topics: Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Time Factors; Tyrosine | 1981 |
Developmental aspects of pteridine metabolism and relationships with phenylalanine metabolism.
Topics: Adolescent; Adult; Aging; Amniotic Fluid; Animals; Biopterins; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neopterin; Phenylalanine; Phenylketonurias; Pregnancy; Pteridines; Rats; Rats, Inbred Strains | 1981 |
Maternal phenylketonuria: the outcome of pregnancy.
Topics: Abortion, Missed; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1981 |
Amino acid carriers at maternal and fetal surfaces of the placenta by single circulation paired-tracer dilution. Kinetics of phenylalanine transport.
Topics: Amino Acids; Animals; Female; Glucose; Guinea Pigs; Kinetics; Maternal-Fetal Exchange; Perfusion; Phenylalanine; Placenta; Pregnancy | 1980 |
Maternal phenylketonuria and hyperphenylalaninemia. An international survey of the outcome of untreated and treated pregnancies.
Topics: Abortion, Spontaneous; Birth Weight; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Intellectual Disability; Intelligence; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1980 |
Ethanol induced changes of in vitro protein synthesis during the development and maturation of brain tissue.
Topics: Animals; Animals, Newborn; Brain; Ethanol; Female; Gestational Age; In Vitro Techniques; Leucine; Male; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Rats; Ribosomes | 1980 |
Phenylketonuria: epitome of human biochemical genetics (second of two parts).
Topics: Child, Preschool; Diagnosis, Differential; Diet; Female; Genetic Carrier Screening; Homeostasis; Humans; Infant; Infant, Newborn; Intelligence Tests; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy | 1980 |
Maternal phenylketonuria: abnormal baby despite low phenylalanine diet during pregnancy.
Topics: Congenital Abnormalities; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pierre Robin Syndrome; Pregnancy; Pregnancy Complications | 1980 |
Influence of acidosis and lactate on protein degradation in adult and fetal hearts.
Topics: Acidosis; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Female; Heart; Lactates; Male; Mice; Myocardium; Organ Culture Techniques; Perfusion; Phenylalanine; Pregnancy; Proteins; Rats | 1980 |
Free amino acids in plasma and muscle of high yielding dairy cows in early lactation.
Topics: Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Cattle; Female; Glutamic Acid; Glutamine; Labor, Obstetric; Lactation; Methionine; Muscles; Phenylalanine; Pregnancy | 1995 |
A mutation of angiotensinogen in a patient with preeclampsia leads to altered kinetics of the renin-angiotensin system.
Topics: Angiotensinogen; Base Sequence; Female; Humans; Kinetics; Leucine; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptides; Phenylalanine; Point Mutation; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System; Substrate Specificity | 1995 |
Outcome in offspring of women with mild hyperphenylalaninaemia.
Topics: Birth Weight; Female; Head; Humans; Infant, Newborn; Intelligence; Intelligence Tests; Phenylalanine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects | 1995 |
The Maternal Phenylketonuria Collaborative Study: a status report.
Topics: Abortion, Spontaneous; Adolescent; Adult; Congenital Abnormalities; Embryonic and Fetal Development; Female; Follow-Up Studies; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Intellectual Disability; Nutritional Physiological Phenomena; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Pregnancy Outcome; Prospective Studies | 1994 |
Kinetics of blood free and milk casein-amino acid labelling in the dairy goat at two stages of lactation.
Topics: Amino Acids; Animals; Caseins; Female; Gestational Age; Goats; Lactation; Leucine; Methionine; Milk; Milk Proteins; Phenylalanine; Pregnancy; Proteins; Valine | 1994 |
[Maternal phenylketonuria: a misdiagnosed cause of embryopathy or fetal disease].
Topics: Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Teratogens | 1994 |
Maternal mild hyperphenylalaninaemia: an international survey of offspring outcome.
Topics: Adolescent; Adult; Birth Weight; Child; Child, Preschool; Data Collection; Female; Head; Humans; Infant, Newborn; Intelligence; Phenylalanine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects | 1994 |
Maternal mild hyperphenylalaninemia: results of treated and untreated pregnancies in two sisters.
Topics: Adult; Child Development; Diabetes, Gestational; Female; Genotype; Humans; Infant; Infant, Newborn; Intelligence; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1994 |
Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term.
Topics: Chromatography, Ion Exchange; Congenital Abnormalities; Cordocentesis; Female; Fetal Blood; Gestational Age; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Ultrasonography | 1994 |
Failure of dietary amino acid supplementation at weaning to influence reproductive traits of sows.
Topics: Amino Acids; Animal Feed; Animals; Estrus; Female; Fetal Death; Food, Fortified; Glutamates; Glutamic Acid; Litter Size; Ovulation; Parity; Phenylalanine; Pregnancy; Reproduction; Swine; Tyrosine; Weaning | 1993 |
Effect of excess phenylalanine diet during pregnancy on fetal brain growth in rats.
Topics: Amino Acids; Animal Feed; Animals; Body Weight; Brain; Brain Chemistry; Eating; Female; Fetal Growth Retardation; Fetal Organ Maturity; Phenylalanine; Pregnancy; Rats; Rats, Sprague-Dawley; Reproduction | 1993 |
The effects of tumour necrosis factor-alpha on circulating amino acids in the pregnant rat.
Topics: Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Animals; Female; Phenylalanine; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Recombinant Proteins; Reference Values; Tumor Necrosis Factor-alpha | 1994 |
Pregnancy complicated by maternal phenylketonuria.
Topics: Female; Fetal Diseases; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies | 1993 |
Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.
Topics: Amino Acids; Biological Transport; Cell Line; Choline; Choriocarcinoma; Female; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kinetics; Leucine; Phenylalanine; Pregnancy; Sodium; Thyroxine; Triiodothyronine; Tritium; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms | 1994 |
Experimental research on a fetal treatment for tetrahydrobiopterin deficiency.
Topics: Adrenal Glands; Animals; Biopterins; Corpus Striatum; Dopamine; Epinephrine; Female; Fetal Blood; Guinea Pigs; Hypoxanthines; Infusions, Intravenous; Liver; Maternal-Fetal Exchange; Metabolism, Inborn Errors; Norepinephrine; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1993 |
Experimental research on a new treatment for maternal phenylketonuria(PKU).
Topics: Animals; Biopterins; Brain; Disease Models, Animal; Female; Fetus; Guinea Pigs; Infusions, Intravenous; Liver; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1993 |
Protein turnover in the human fetus studied at term using stable isotope tracer amino acids.
Topics: Adult; Amino Acids; Carbon Isotopes; Delivery, Obstetric; Female; Fetal Blood; Humans; Leucine; Maternal-Fetal Exchange; Nitrogen Isotopes; Osmolar Concentration; Phenylalanine; Pregnancy; Proteins | 1993 |
[Maternal hyperphenylalaninemia].
Topics: Female; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1993 |
Maternal and infant serum phenylalanine levels and pregnancy outcome in infants of nonphenylketonuric mothers.
Topics: Apgar Score; Birth Weight; Female; Fetal Blood; Humans; Infant, Low Birth Weight; Infant, Newborn; Phenylalanine; Pregnancy | 1993 |
[Embryofetopathy of the newborn infant of a phenylketonuric mother. A diagnosis not to be missed].
Topics: Adult; Female; Fetal Diseases; Fetal Growth Retardation; Heart Septal Defects; Humans; Infant, Newborn; Intellectual Disability; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1993 |
Recommendations on the dietary management of phenylketonuria. Report of Medical Research Council Working Party on Phenylketonuria.
Topics: Adolescent; Child; Child, Preschool; Counseling; Female; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 1993 |
Phenylketonuria: variable phenotypic outcomes of the R261Q mutation and maternal PKU in the offspring of a healthy homozygote.
Topics: Adult; Child; Female; Haplotypes; Heterozygote; Homozygote; Humans; Male; Maternal-Fetal Exchange; Mutation; Pedigree; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications | 1993 |
The use of gelatin capsules for ingestion of formula in dietary treatment of maternal phenylketonuria.
Topics: Adult; Amino Acids; Capsules; Female; Food, Formulated; Gelatin; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1993 |
The effect of nutrient intake on pregnancy outcome in maternal phenylketonuria.
Topics: Female; Humans; Nutritional Physiological Phenomena; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 1993 |
Mid-second trimester organic acids in severe open neural tube defects.
Topics: Amniocentesis; Amniotic Fluid; Anencephaly; Female; Humans; Hydrolases; Phenylalanine; Pregnancy; Pregnancy Trimester, Second; Spinal Dysraphism; Tyrosine | 1995 |
[Maternal hyperphenylalaninemia in a population of healty Czech women. 18 years' experience with mass screening, diet therapy and metabolic monitoring].
Topics: Adolescent; Adult; Czech Republic; Female; Humans; Incidence; Infant, Newborn; Mass Screening; Phenylalanine; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy; Pregnancy Complications | 1996 |
Maternal phenylketonuria: magnetic resonance imaging of the brain in offspring.
Topics: Adolescent; Agenesis of Corpus Callosum; Brain; Child; Corpus Callosum; Female; Follow-Up Studies; Humans; Infant; Intellectual Disability; Magnetic Resonance Imaging; Male; Microcephaly; Mothers; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Exposure Delayed Effects | 1996 |
Glucose and amino acid turnover in untreated gestational diabetes.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Calorimetry; Carbon Dioxide; Carbon Isotopes; Diabetes, Gestational; Female; Glucose; Humans; Infusions, Intravenous; Insulin; Leucine; Oxygen Consumption; Phenylalanine; Pregnancy; Reference Values; Regression Analysis | 1996 |
Effects of circulating IGF-I on glucose and amino acid kinetics in the ovine fetus.
Topics: Amino Acids; Animals; Fasting; Female; Fetus; Glucose; Homeostasis; Humans; Hydroxylation; Insulin-Like Growth Factor I; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Placenta; Pregnancy; Recombinant Proteins; Sheep | 1996 |
Recommendations for protein and amino acid intake in phenylketonuric patients.
Topics: Adolescent; Adult; Amino Acids; Diet, Protein-Restricted; Dietary Proteins; Female; Humans; Male; Nutritional Requirements; Phenylalanine; Phenylketonurias; Pregnancy; Weaning | 1996 |
Nutrition and reproductive outcome in maternal phenylketonuria.
Topics: Diet, Protein-Restricted; Dietary Proteins; Female; Humans; Nutrition Assessment; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Weight Gain | 1996 |
Maternal phenylketonuria. A study from the United Kingdom.
Topics: Child Development; Diet, Protein-Restricted; Female; Humans; Infant; Intelligence; Patient Compliance; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; United Kingdom | 1996 |
Placental tyrosine transport and maternal phenylketonuria.
Topics: Cell Membrane; Culture Techniques; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Microvilli; Phenylalanine; Placenta; Pregnancy; Trophoblasts; Tyrosine | 1996 |
Maternal hyperphenylalaninaemia as a cause of microcephaly and mental retardation.
Topics: Adult; Female; Humans; Intellectual Disability; Intelligence; Maternal-Fetal Exchange; Microcephaly; Middle Aged; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic | 1996 |
Microcephaly in a hyperphenylalaninemic infant leading to the diagnosis of maternal hyperphenylalaninemia.
Topics: Consanguinity; Female; Humans; Infant; Infant, Newborn; Microcephaly; Neonatal Screening; Phenylalanine; Phenylketonurias; Pregnancy; Reference Values | 1996 |
RB 101, a purported pro drug inhibitor of enkephalin metabolism, is antinociceptive in pregnant mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Depression, Chemical; Disulfides; Enkephalins; Female; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain Threshold; Phenylalanine; Pregnancy; Pregnancy, Animal; Prodrugs; Respiration | 1997 |
Social factors and the meaning of food in adherence to medical diets: results of a maternal phenylketonuria summer camp.
Topics: Adolescent; Adult; Child; Diet, Protein-Restricted; Female; Follow-Up Studies; Food; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Social Support | 1997 |
Maternal Phenylketonuria Collaborative Study (MPKUCS) offspring: facial anomalies, malformations, and early neurological sequelae.
Topics: Cohort Studies; Cooperative Behavior; Face; Female; Humans; Nervous System; Nervous System Diseases; Nervous System Malformations; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 1997 |
Cardiovascular defects among the progeny of mouse phenylketonuria females.
Topics: Animals; Blood Vessels; Diet; Disease Models, Animal; Female; Genotype; Heart Defects, Congenital; Humans; Maternal-Fetal Exchange; Mice; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1997 |
Maternal PKU and breastfeeding: case report of identical twin mothers.
Topics: Adult; Breast Feeding; Diseases in Twins; Female; Humans; Milk, Human; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1997 |
[Serotonin is involved in the development of luliberin-produced system of rat's brain in prenatal period].
Topics: Animals; Brain; Female; Gonadotropin-Releasing Hormone; Male; Phenylalanine; Pregnancy; Rats; Rats, Wistar; Serotonin | 1997 |
Reply to SP Bessman.
Topics: Diet; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1998 |
Neonatal neurological assessment of offspring in maternal phenylketonuria.
Topics: Developmental Disabilities; Female; Follow-Up Studies; Humans; Infant, Newborn; Male; Neurologic Examination; Neuropsychological Tests; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 1998 |
[An experimental study on the effects of maternal hyperphenylalaninemia on the central nervous system and behavior of offspring rats].
Topics: Amino Acids, Branched-Chain; Animals; Animals, Newborn; Behavior, Animal; Brain; Enzyme Inhibitors; Female; Fenclonine; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Pregnancy; Rats; Rats, Wistar; Synaptosomes | 1998 |
Possible involvement of placental proteases in bradykinin (BK) degradation.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Arginine; Blood; Bradykinin; Captopril; Endopeptidases; Female; Glycopeptides; Humans; Hydrolysis; Lysine Carboxypeptidase; Microsomes; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Placenta; Pregnancy | 1997 |
Mild hyperphenylalaninemia and heterozygosity of the phenylalanine hydroxylase gene.
Topics: Adult; Female; Follow-Up Studies; Genetic Carrier Screening; Humans; Infant, Newborn; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Pregnancy | 1998 |
Maternal phenylketonuria.
Topics: Abortion, Therapeutic; Adult; Aortic Coarctation; Child; Child, Preschool; Female; Fetal Growth Retardation; Humans; Infant; Infant, Newborn; Intelligence Tests; Male; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Respiratory Distress Syndrome, Newborn | 1998 |
L-tryptophan in maternal phenylketonuria.
Topics: Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tryptophan; Tyrosine | 1998 |
Rat amnion type IV collagen composition and metabolism: implications for membrane breakdown.
Topics: Adenoviridae; Amnion; Animals; Apoptosis; Basement Membrane; Collagen; Collagenases; Extraembryonic Membranes; Female; Gelatinases; Labor, Obstetric; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Organ Culture Techniques; Phenylalanine; Pregnancy; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Thiophenes; Transfection | 1999 |
Assessment of the reliability of single blastomere analysis for preimplantation diagnosis of the delta F508 deletion causing cystic fibrosis in clinical practice.
Topics: Biopsy; Blastomeres; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Embryonic Development; Female; Gene Deletion; Genotype; Heterozygote; Humans; Phenylalanine; Polymerase Chain Reaction; Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity | 1998 |
Maternal phenylketonuria in two Sicilian families identified by maternal blood phenylalanine level screening and identification of a new phenylalanine hydroxylase gene mutation (P407L)
Topics: Female; Genetic Testing; Humans; Infant, Newborn; Italy; Mutation; Neonatal Screening; Pedigree; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Phenylketonurias; Pregnancy | 1999 |
Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria.
Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Brain; Brain Chemistry; Diet; Embryonic and Fetal Development; Female; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats; Rats, Long-Evans | 1999 |
Maternal phenylketonuria: a continuing problem.
Topics: Adolescent; Adult; Databases, Factual; Female; Humans; Neonatal Screening; New South Wales; Phenylalanine; Phenylketonuria, Maternal; Population Surveillance; Pregnancy; Pregnancy Outcome | 1999 |
Evaluation of phenylalanine and tyrosine metabolism in late human pregnancy.
Topics: Adult; Female; Homeostasis; Humans; Hydroxylation; Keto Acids; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proteins; Tyrosine | 1999 |
Repeated adverse fetal outcome in pregnancy complicated by uncontrolled maternal phenylketonuria.
Topics: Adult; Female; Fetal Diseases; Humans; Intellectual Disability; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Syndrome | 1999 |
Necessity of complete intake of phenylalanine-free amino acid mixture for metabolic control of phenylketonuria.
Topics: Adult; Amino Acids; Child, Preschool; Diet, Protein-Restricted; Eating; Female; Humans; Patient Compliance; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome | 1999 |
When is careless conception a form of child abuse? Lessons from maternal phenylketonuria.
Topics: Adolescent; Adult; Embryonic and Fetal Development; Female; Fetal Diseases; Heart Defects, Congenital; Humans; Infant; Maternal Behavior; Microcephaly; Phenylalanine; Phenylketonurias; Physician-Patient Relations; Preconception Care; Pregnancy; Pregnancy Complications | 2000 |
Maternal phenylketonuria syndrome: congenital heart defects, microcephaly, and developmental outcomes.
Topics: Adult; Child Development; Cohort Studies; Developmental Disabilities; Diet; Female; Follow-Up Studies; Genotype; Gestational Age; Heart Defects, Congenital; Humans; Infant, Newborn; Intelligence; Medical Records; Microcephaly; Mutation; Phenylalanine; Phenylketonurias; Preconception Care; Pregnancy; Pregnancy Complications; Psychomotor Performance; Risk Factors; Ultrasonography, Prenatal | 2000 |
The international study of pregnancy outcome in women with maternal phenylketonuria: report of a 12-year study.
Topics: Adult; Child; Child, Preschool; Cognition Disorders; Diet, Protein-Restricted; Educational Status; Female; Heart Defects, Congenital; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Prospective Studies; Social Class | 2000 |
Regulation of myofibrillar protein turnover during maturation in normal and undernourished rat pups.
Topics: Actins; Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Female; Gene Expression Regulation, Developmental; Muscle Development; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Myofibrils; Myosins; Phenylalanine; Pregnancy; Rats; Rats, Sprague-Dawley; Ribosomes; RNA, Messenger; Sarcoplasmic Reticulum; Tritium; Tropomyosin | 2000 |
[Pseudo-inherited form of left heart obstructive defects revealing maternal phenylketonuria].
Topics: Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Microcephaly; Nuclear Family; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 2000 |
Nutritional factors affecting serum phenylalanine concentration during pregnancy for identical twin mothers with phenylketonuria.
Topics: Adult; Dietary Fats; Dietary Proteins; Diseases in Twins; Female; Humans; Nutritional Physiological Phenomena; Phenylalanine; Phenylketonuria, Maternal; Pregnancy | 2000 |
Effect of phenylalanine and its metabolites on the proliferation and viability of neuronal and astroglial cells: possible relevance in maternal phenylketonuria.
Topics: Astrocytes; Cell Division; Cell Survival; Female; Humans; Neurons; Phenethylamines; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Thymidine; Tumor Cells, Cultured | 2000 |
The International Collaborative Study of Maternal Phenylketonuria: status report 1998.
Topics: Adult; Congenital Abnormalities; Female; Genotype; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Research | 2000 |
Whole body protein kinetics in women: effect of pregnancy and IDDM during anabolic stimulation.
Topics: Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Female; Glucose Clamp Technique; Humans; Hydroxylation; Insulin; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Proteins | 2000 |
An in vivo study of ovine placental transport of essential amino acids.
Topics: Amino Acids; Animals; Female; Histidine; Isoleucine; Leucine; Lysine; Methionine; Oxygen Consumption; Phenylalanine; Placenta; Placental Circulation; Pregnancy; Sheep; Threonine; Tryptophan; Umbilical Arteries; Umbilical Veins; Valine | 2001 |
'Mommy, why can't I have a hamburger like the other kids?'.
Topics: Adolescent; Adult; Biopterins; Diet, Protein-Restricted; Female; Genetic Therapy; Humans; Keratinocytes; Metabolic Clearance Rate; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Skin Transplantation | 2000 |
Comments on the International Collaborative Study of Maternal Phenylketonuria: status report 1998.
Topics: Adult; Female; Humans; Multicenter Studies as Topic; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome | 2000 |
Development and de novo protein synthetic activity of bovine embryos produced in vitro in different culture systems.
Topics: Animals; Blastocyst; Blastomeres; Cattle; Citrates; Culture Media, Serum-Free; Embryonic and Fetal Development; Epidermal Growth Factor; Female; Fertilization in Vitro; Histocytochemistry; Male; Phenylalanine; Polyvinyl Alcohol; Pregnancy; Protein Biosynthesis; Proteins; Random Allocation; Serum Albumin, Bovine; Sodium Citrate; Zygote | 2001 |
Intake of major nutrients by women in the Maternal Phenylketonuria (MPKU) Study and effects on plasma phenylalanine concentrations.
Topics: Diet Records; Dietary Fats; Dietary Proteins; Energy Intake; Female; Genotype; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Weight Gain | 2001 |
[Dietary recommendations for pregnant women affected with phenylketonuria].
Topics: Adult; Diet; Female; Humans; Nutrition Policy; Nutritional Status; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Risk Factors | 2001 |
[Maternal phenylketonuria].
Topics: Adult; Congenital Abnormalities; Diet, Protein-Restricted; Energy Intake; Female; Fetal Growth Retardation; Gestational Age; Humans; Nutritional Requirements; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prenatal Care; Risk Factors; Tyrosine | 2001 |
Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies.
Topics: Adult; Amino Acids; Animals; Biological Transport, Active; Female; Fetal Growth Retardation; Fetus; Glycine; Humans; Leucine; Phenylalanine; Placenta; Pregnancy; Proline; Sheep | 2001 |
Effect of maternal blood phenylalanine level on mouse maternal phenylketonuria offspring.
Topics: Abortion, Spontaneous; Animals; Disease Models, Animal; Embryonic and Fetal Development; Female; Fetal Diseases; Humans; Male; Mice; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Tyrosine | 2001 |
Glutamine and leucine nitrogen kinetics and their relation to urea nitrogen in newborn infants.
Topics: Blood Urea Nitrogen; Carbon Isotopes; Deuterium; Female; Glutamine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Kinetics; Leucine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Urea | 2002 |
Canine serum alkaline phosphatase isoenzymes detected by polyacrylamide gel disk electrophoresis.
Topics: Age Factors; Alkaline Phosphatase; Animals; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Ileum; Isoenzymes; Kidney; Levamisole; Liver; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Reagent Kits, Diagnostic; Wheat Germ Agglutinins | 2002 |
[Phenylketonuria outgrows childhood shoes. How much is diet still necessary?].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Infant; Infant, Newborn; Male; Neonatal Screening; Patient Care Team; Phenylalanine; Phenylketonurias; Pregnancy; Survival Rate | 2002 |
Description of a new mutation in hepatoerythropoietic porphyria and prenatal exclusion of a homozygous fetus.
Topics: Amino Acid Substitution; Child, Preschool; Chromosome Aberrations; Codon; Consanguinity; Female; Genes, Recessive; Genetic Carrier Screening; Homozygote; Humans; Leucine; Male; Mutation; Phenylalanine; Porphyria, Erythropoietic; Pregnancy; Prenatal Diagnosis; Uroporphyrinogen Decarboxylase | 2002 |
Clinical usefulness of alkaline phosphatase isoenzyme determinations.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Bone and Bones; Child; Child, Preschool; Female; gamma-Glutamyltransferase; Humans; Intestines; Isoenzymes; Liver; Middle Aged; Phenylalanine; Pregnancy; Urea | 1977 |
Placenta-like alkaline phosphatases from human osteosarcoma cells.
Topics: Alkaline Phosphatase; Bone and Bones; Cells, Cultured; Enzyme Induction; Female; Hot Temperature; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Isoenzymes; Neoplasms, Experimental; Osteosarcoma; Phenylalanine; Placenta; Pregnancy | 1978 |
Human dihydropteridine reductase: a method for the measurement of activity in cultured cells, and its application to malignant hyperphenylalaninemia.
Topics: Amniotic Fluid; Animals; Cells, Cultured; Dihydropteridine Reductase; Female; Humans; Hydrogen-Ion Concentration; Liver; Lymphocytes; Male; Methods; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Sheep; Temperature | 1979 |
Fetal damage despite low-phenylalanine diet after conception in a phenylketonuric woman.
Topics: Abnormalities, Multiple; Brain; Congenital Abnormalities; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Care | 1979 |
Conception in a phenylketonuric woman.
Topics: Adult; Child; Congenital Abnormalities; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First | 1979 |
Successful outcome of pregnancy in a phenylketonuric woman after low-phenylalanine diet introduced before conception.
Topics: Female; Follow-Up Studies; Humans; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Care | 1979 |
The growing problems of phenylketonuria.
Topics: Age Factors; Child, Preschool; Female; Gestational Age; Humans; Infant, Newborn; Intellectual Disability; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy | 1979 |
Hyperphenylalaninaemia and pregnancy.
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Diagnosis | 1979 |
Carcinoembryonic proteins in gastric carcinoma metastatic to the liver.
Topics: Adult; Alkaline Phosphatase; alpha-Fetoproteins; Carcinoembryonic Antigen; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Hot Temperature; Humans; Leucine; Liver Neoplasms; Male; Phenylalanine; Placenta; Pregnancy; Stomach Neoplasms | 1979 |
Urinary metabolites of phenylalanine in the preweanling rat treated with p-chlorophenylalanine and phenylalanine.
Topics: Animals; Chromatography; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fenclonine; Hippurates; Humans; Lactation; Male; Molecular Conformation; Phenylacetates; Phenylalanine; Phenylketonurias; Pregnancy; Rats | 1975 |
Biochemical effects of induced phenylketonuria in rats.
Topics: Amino Acids; Amniotic Fluid; Animals; Brain; Diet; Female; Fenclonine; Fetal Blood; Humans; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Rats; Serotonin; Tyrosine | 1975 |
Brain pyruvate kinase activity in PKU model systems.
Topics: Animals; Body Weight; Brain; Female; Fenclonine; Fetus; Humans; Organ Size; Phenylalanine; Phenylketonurias; Pregnancy; Pyruvate Kinase; Rats; Tyrosine | 1979 |
Chloramphenicol/thiamphenicol and cycloheximide as tools for the measurement of mitochondrial protein synthesis in vitro during organogenesis of rat embryos.
Topics: Animals; Anti-Bacterial Agents; Autoradiography; Cell Fractionation; Chloramphenicol; Cycloheximide; Electron Transport Complex IV; Embryo, Mammalian; Female; Gestational Age; Methods; Microsomes; Mitochondria; Morphogenesis; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; Rats, Inbred Strains; Thiamphenicol | 1975 |
Phenylalanine-pyruvate aminotransferase in immature and adult mammalian tissues. Induction in fetal rat liver.
Topics: Adult; Aging; Animals; Brain; Carcinoma, Hepatocellular; Enzyme Induction; Female; Fetus; Gestational Age; Humans; Liver; Liver Neoplasms; Lung; Neoplasms, Experimental; Organ Specificity; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Pyruvates; Rats; Species Specificity; Structure-Activity Relationship; Transaminases | 1977 |
Comparison of properties of human intestinal and placental alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acids; Female; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Kinetics; Molecular Weight; Phenylalanine; Phosphates; Placenta; Pregnancy; Temperature | 1975 |
Diet, genetics, and mental retardation interaction between phenylketonuric heterozygous mother and fetus to produce nonspecific diminution of IQ: evidence in support of the justification hypothesis.
Topics: Diet; Female; Heterozygote; Humans; Intelligence; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine; Wechsler Scales | 1978 |
Subclinical protein-energy malnutrition in under-privileged Ethiopian mothers and their newborn infants.
Topics: Adolescent; Adult; Developing Countries; Ethiopia; Female; Fetal Blood; Glycine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Methionine; Phenylalanine; Pregnancy; Pregnancy Complications; Protein-Energy Malnutrition; Socioeconomic Factors; Tyrosine; Valine | 1978 |
Free and bound tryptophan in human plasma during the perinatal period.
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Infant, Premature; Labor, Induced; Male; Phenylalanine; Pregnancy; Protein Binding; Serum Albumin; Tryptophan; Tyrosine | 1979 |
Management of maternal phenylketonuria: an emerging clinical problem.
Topics: Cephalometry; Female; Humans; Infant, Newborn; Intelligence; Mental Disorders; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1979 |
The purification of alkaline phosphatase from rat uterine deciduomata and the raising of a specific antiserum.
Topics: Alkaline Phosphatase; Animals; Decidua; Endometrium; Female; Imidazoles; Isoelectric Point; Myometrium; Neuraminidase; Phenylalanine; Pregnancy; Rats; Substrate Specificity | 1979 |
[Principles of dietary treatment in phenylalanine metabolism disturbancies in pregnancy (author's transl].
Topics: Adolescent; Adult; Diet; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic | 1979 |
Use of specific inhibitors to disciminate alkaline phosphatase isoenzymes originating from human liver, placenta and intestine: absence of meconial alkaline phosphatase in maternal serum.
Topics: Alkaline Phosphatase; Amniotic Fluid; Female; Humans; Intestines; Isoenzymes; Liver; Maternal-Fetal Exchange; Meconium; Phenylalanine; Placenta; Pregnancy; Tetramisole | 1979 |
[Maternal hyperphenylalaninemia as a cause of embryo-fetal disease. Review of literature and clinical contribution].
Topics: Abnormalities, Multiple; Female; Fetal Death; Fetal Diseases; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1979 |
Relative inability of mother and child to convert phenylalanine of tyrosine--a possible cause of nonspecific mental retardation.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Heterozygote; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1979 |
Plasma, erythrocyte and human milk levels of free amino acids in lactating women administered aspartame or lactose.
Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Breast Feeding; Dipeptides; Erythrocytes; Female; Humans; Infant; Infant, Newborn; Lactation; Lactose; Milk, Human; Phenylalanine; Pregnancy | 1979 |
The dietary management of phenylketonuria.
Topics: Age Factors; Child; Child, Preschool; Dietary Proteins; Female; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1979 |
Treatment of phenylketonuria.
Topics: Adult; Child; Child Behavior Disorders; Dihydroxyphenylalanine; Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Time Factors; Tryptophan | 1979 |
Maternal phenylketonuria: dietary treatment during pregnancy.
Topics: Adult; Child Development; Dietary Proteins; Female; Humans; Infant, Newborn; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy Trimester, Second | 1979 |
Decreased foetal amino acid uptake, brain pyruvate kinase and intrauterine damage in maternal PKU.
Topics: Amino Acids; Animals; Brain; Female; Fetus; Hexokinase; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pyruvate Kinase; Rats; Succinate Dehydrogenase; Tryptophan; Tyrosine | 1977 |
Induced PKU in rats: effects of age and melatonin treatment.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Humans; Learning; Melatonin; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Time Factors; Tyrosine | 1977 |
Beneficial effect of isoleucine on fetal brain development in induced phenylketonuria.
Topics: Amino Acids; Animals; Body Weight; Brain; Disease Models, Animal; Female; Humans; Isoleucine; Organ Size; Phenylalanine; Phenylketonurias; Pregnancy; Rats | 1978 |
[Treatment of diabetes during pregnancy with Des-Phe insulin: preliminary results (author's transl)].
Topics: Adult; Female; Humans; Hyperinsulinism; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Insulin Antibodies; Phenylalanine; Pregnancy; Pregnancy in Diabetics | 1979 |
[Hyperphenylalaninemia during pregnancy].
Topics: Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic | 1977 |
Anatomy of a trial.
Topics: Child, Preschool; Female; Humans; Infant; Infant, Newborn; Intelligence Tests; Phenylalanine; Phenylketonurias; Pregnancy; Stanford-Binet Test | 1977 |
Ribosomal activity in prenatal mouse brain.
Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Animals, Newborn; Brain; Female; Mice; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Ribosomes | 1978 |
Phenylketonuria heterozygote detection in families with affected children.
Topics: Ethnicity; Female; Genetic Counseling; Heterozygote; Humans; Indiana; Male; Michigan; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Selection, Genetic; Sex Factors; Tryptophan; Tyrosine | 1978 |
Variability of reproductive casualty in maternal phenylalaninemia.
Topics: Abortion, Therapeutic; Birth Weight; Congenital Abnormalities; Female; Fetal Death; Humans; Intellectual Disability; Intelligence; Male; Parents; Phenylacetates; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Care; Risk | 1978 |
Changes in free amino acids and peptides in the haemolymph of Glossina austeni during the reproductive cycle.
Topics: Amino Acids; Animals; Aspartic Acid; Female; Hemolymph; Hydrolysis; Lysine; Peptides; Phenylalanine; Pregnancy; Tsetse Flies; Tyrosine | 1978 |
Comparison of the anti-LH/FSH-RH and anti-ovulatory activities of (D-Phe2, D-Leu6)-LH-RH and (D-Phe2, D-Ala6)-LH-RH.
Topics: Alanine; Animals; Estrus; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Leucine; Luteinizing Hormone; Male; Ovulation; Phenylalanine; Pituitary Hormone Release Inhibiting Hormones; Pregnancy; Rats; Structure-Activity Relationship | 1976 |
L-leucine sensitive alkaline phosphatase isozyme from cancer tissue.
Topics: Alkaline Phosphatase; Drug Stability; Edetic Acid; Female; Hot Temperature; Humans; Isoenzymes; Kinetics; Leucine; Neoplasms; Phenylalanine; Placenta; Precipitin Tests; Pregnancy | 1975 |
L-p-Bromotetramisole, a new reagent for use in measuring placental or intestinal isoenzymes of alkaline phosphatase in human serum.
Topics: Alkaline Phosphatase; Buffers; Female; Hot Temperature; Humans; Intestines; Isoenzymes; Levamisole; Phenylalanine; Placenta; Pregnancy; Protein Denaturation; Tetramisole; Time Factors | 1977 |
Nutritional management of the female with phenylketonuria during pregnancy.
Topics: Amino Acids, Essential; Birth Weight; Congenital Abnormalities; Female; Humans; Menu Planning; Microcephaly; Nutritional Requirements; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1977 |
[A mother with hyperphenylalaninemia and development of the fetus during a diet in pregnancy].
Topics: Female; Humans; Infant, Newborn; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1977 |
Metabolism of L-(U-14C)valine, L-(U-14C)leucine, L-(U-14C)histidine and L-(U-14C) phenylalanine by the isolated perfused lactating guinea-pig mammary gland.
Topics: Amino Acids, Essential; Animals; Caseins; Female; Glutamates; Guinea Pigs; Histidine; In Vitro Techniques; Lactation; Leucine; Mammary Glands, Animal; Perfusion; Phenylalanine; Pregnancy; Tyrosine; Valine | 1976 |
Reduction by cycloheximide of lysosomal proteolytic enzyme activity and rate of protein degradation in organ-cultured hearts.
Topics: Acetylglucosaminidase; Acid Phosphatase; Animals; Cathepsins; Creatine Kinase; Cycloheximide; Female; Fetal Heart; Lysosomes; Mice; Organ Culture Techniques; Peptide Hydrolases; Phenylalanine; Pregnancy | 1976 |
Maternal hyperphenylalaninemia: an experimental model in rats.
Topics: Animals; Animals, Newborn; Birth Weight; Brain Chemistry; Disease Models, Animal; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Placenta; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred F344; Time Factors | 1976 |
[Obstetrical problems of phenylketonuria].
Topics: Adult; Female; Humans; Intellectual Disability; Male; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Diagnosis | 1976 |
Phenylketonuria.
Topics: Female; Humans; Infant, Newborn; Intellectual Disability; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1975 |
Progeny, pregnancy and phenylketonuria.
Topics: Adolescent; Adult; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Myocardium; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1975 |
Letter: Hazards in indiscriminate use of sweeteners containing phenylalanine.
Topics: Aspartic Acid; Diet; Dipeptides; Female; Fetus; Heterozygote; Homozygote; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Sweetening Agents | 1975 |
Letter: Safety of aspartame as a sweetener.
Topics: Aspartic Acid; Dipeptides; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Sweetening Agents | 1975 |
Latrogenesis imperfecta--a new pediatric problem.
Topics: Amniotic Fluid; Clinical Laboratory Techniques; Cushing Syndrome; Diagnostic Errors; Disease; False Positive Reactions; Female; Health; Humans; Male; Mass Screening; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Pregnancy | 1975 |
[Pregnancy hyperphenylalanemia and its diagnostic importance (author's transl)].
Topics: Female; Humans; Infant, Newborn; Intelligence Tests; Male; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1975 |
[Mother with phenylketonuria and foetal development].
Topics: Female; Fetus; Growth; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1975 |
Serum amino acid concentrations during pregnancy of women heterozygous for phenylketonuria.
Topics: Amino Acids; Female; Fetal Blood; Heterozygote; Humans; Phenylalanine; Pregnancy; Thyrotropin | 1975 |
The phenylalanine and tyrosine contnet of maternal and fetal body fluids from rabbits fed aspartame.
Topics: Amino Acids; Amniotic Fluid; Animals; Aspartame; Body Fluids; Body Weight; Dipeptides; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Rabbits; Tyrosine | 1975 |
Systems constituting the metabolic sequence in the cell cycle.
Topics: Amino Acids; Animals; Cell Division; Cell Physiological Phenomena; Cells; DNA Nucleotidyltransferases; Embryo, Mammalian; Embryo, Nonmammalian; Female; Fertilization; Ovum; Peptide Biosynthesis; Phenylalanine; Pregnancy; Protein Biosynthesis; Ribosomes; RNA, Transfer; Time Factors; Transfer RNA Aminoacylation | 1975 |
Pyruvate kinase isoenzymes in tissues of the developing guinea pig.
Topics: Age Factors; Alanine; Animals; Animals, Newborn; Brain; Female; Fetus; Guinea Pigs; Isoenzymes; Kidney; Kinetics; Liver; Muscle Development; Muscles; Organ Specificity; Phenylalanine; Pregnancy; Pyruvate Kinase | 1975 |
Isolation and characterization of active ribosomal subunits from human placenta.
Topics: Cell Fractionation; Centrifugation, Density Gradient; Centrifugation, Zonal; Female; Humans; Kinetics; Magnesium; Phenylalanine; Placenta; Poly U; Pregnancy; Protein Biosynthesis; Ribosomes; RNA, Transfer; Temperature | 1975 |
Practical aspects on the determination of serum alkaline phosphatase isoenzymes using L-phenylalanine and urea.
Topics: Alkaline Phosphatase; Bone Neoplasms; Child; Child, Preschool; Female; Hot Temperature; Humans; Intestines; Isoenzymes; Liver; Liver Diseases; Phenylalanine; Pregnancy; Urea | 1975 |
Phenylketonuria as a balanced polymorphism: the nature of the heterozygote advantage.
Topics: Abortion, Spontaneous; Birth Weight; Female; Fetal Death; Gene Frequency; Heterozygote; Humans; Ireland; Mutation; Nutritional Physiological Phenomena; Parity; Phenylalanine; Phenylketonurias; Polymorphism, Genetic; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Scotland; Zygote | 1975 |
Sequence studies on tRNAPhe from placenta: comparison with known sequences of tRNAPhe from other normal mammalian tissues.
Topics: Base Sequence; Female; Humans; Nucleic Acid Conformation; Oligonucleotides; Organ Specificity; Phenylalanine; Placenta; Pregnancy; Ribonucleases; RNA, Transfer | 1975 |
Purification of human placenta phenylalanine, valine, methionine, glucine, and serine transfer ribonucleic acids.
Topics: Chromatography, High Pressure Liquid; Female; Glycine; Humans; Methionine; Phenylalanine; Placenta; Pregnancy; RNA, Transfer; Serine; Valine | 1975 |
The effect of glucose infusion on the plasma free amino acids in sheep.
Topics: Amino Acids; Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Female; Glucose; Infusions, Parenteral; Isoleucine; Lactation; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Pregnancy; Pregnancy, Animal; Sheep; Valine | 1975 |
Serum alkaline phosphatase in pregnancy. I. A comparative study of total, L-phenylanine-sensitive and heat-stable alkaline phosphatase at 56 degrees C and 65 degrees C in normal pregnancy.
Topics: Alkaline Phosphatase; Birth Weight; Female; Hot Temperature; Humans; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third | 1975 |
Studies on the experimental phenylketonuria in rats.
Topics: Amino Acids; Animals; Brain Chemistry; Female; Homogentisic Acid; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Rats; Transaminases; Tyrosine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
[Problem of maternal phenylketonuria].
Topics: Female; Fetal Diseases; Fetus; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1975 |
Placental amino acid uptake. III. Transport systems for neutral amino acids.
Topics: Amino Acids; Aminoisobutyric Acids; Biological Transport; Carboxylic Acids; Female; Humans; In Vitro Techniques; Methylamines; Phenylalanine; Placenta; Pregnancy; Time Factors | 1976 |
Late diagnosis of phenylketonuria in a Bedouin mother.
Topics: Abortion, Habitual; Adult; Child, Preschool; Female; Fetal Diseases; Heart Defects, Congenital; Humans; Infant; Intellectual Disability; Male; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1992 |
Maternal phenylketonuria collaborative study, obstetric aspects and outcome: the first 6 years.
Topics: Congenital Abnormalities; Female; Humans; Longitudinal Studies; Medical Records; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Reference Values | 1992 |
Newborn screening for phenylketonuria: thirty years of progress.
Topics: Adolescent; Adult; Child; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Infant, Newborn; Intelligence Tests; Neonatal Screening; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pterins; Tyrosine | 1992 |
Maternal phenylketonuria.
Topics: Child; Child, Preschool; Developmental Disabilities; Diseases in Twins; Female; Humans; Infant; Intellectual Disability; Intelligence; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy | 1990 |
Pregnancy in phenylketonuria: dietary treatment aimed at normalising maternal plasma phenylalanine concentration.
Topics: Adult; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Preconception Care; Pregnancy; Tyrosine | 1991 |
Maternal PKU collaborative study: the effect of nutrient intake on pregnancy outcome.
Topics: Adult; Body Weight; Dietary Proteins; Energy Intake; Female; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Regression Analysis; Tyrosine | 1991 |
Tissue protein synthesis in lactating and dry goats.
Topics: Animals; Body Composition; Female; Goats; Lactation; Phenylalanine; Pregnancy; Protein Biosynthesis; Tissue Distribution | 1991 |
Management of inborn errors of metabolism during pregnancy.
Topics: Birth Weight; Female; Humans; Infant, Newborn; Metabolism, Inborn Errors; Patient Compliance; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Scotland | 1991 |
Gly429 is the major determinant of uncompetitive inhibition of human germ cell alkaline phosphatase by L-leucine.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Arginine; Base Sequence; Female; Glycine; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Oligopeptides; Phenylalanine; Placenta; Pregnancy; Restriction Mapping; Transfection | 1991 |
Pterins analysis in amniotic fluid for the prenatal diagnosis of GTP cyclohydrolase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Follow-Up Studies; GTP Cyclohydrolase; Humans; Infant, Newborn; Male; Phenylalanine; Pregnancy; Prenatal Diagnosis; Pterins | 1990 |
Further characterization of a heat-stable alkaline phosphatase with low sensitivity to L-phenylalanine.
Topics: Alkaline Phosphatase; Antibodies, Monoclonal; Electrophoresis, Agar Gel; Enzyme Stability; Female; Hot Temperature; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Isoelectric Focusing; Middle Aged; Phenylalanine; Placenta; Pregnancy | 1990 |
Maternal phenylketonuria pregnancy outcome: a preliminary report of facial dysmorphology and major malformations.
Topics: Congenital Abnormalities; Facial Bones; Female; Heart Defects, Congenital; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 1990 |
Early prenatal diagnosis of propionic acidaemia with simultaneous sampling of chorionic villus and amniotic fluid.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Carboxy-Lyases; Cells, Cultured; Chorionic Villi; Female; Humans; Methylmalonyl-CoA Decarboxylase; Phenylalanine; Pregnancy; Prenatal Diagnosis; Propionates | 1990 |
Fetal damage due to maternal phenylketonuria: effects of dietary treatment and maternal phenylalanine concentrations around the time of conception (an interim report from the UK Phenylketonuria Register).
Topics: Adolescent; Adult; Birth Weight; Embryonic and Fetal Development; Female; Head; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1990 |
Phenylalanine and its metabolites induce embryopathies in mouse embryos in culture.
Topics: Animals; Culture Techniques; Female; Mice; Mice, Inbred Strains; Neural Tube Defects; Phenylalanine; Phenylketonurias; Pregnancy; Teratogens | 1990 |
Origin of the left coronary artery from the right pulmonary artery and ventricular septal defect in a child of a mother with raised plasma phenylalanine concentrations throughout pregnancy.
Topics: Abnormalities, Multiple; Coronary Vessel Anomalies; Echocardiography; Female; Fetal Growth Retardation; Heart Defects, Congenital; Heart Septal Defects, Ventricular; Humans; Infant; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Pregnancy Complications; Pulmonary Artery | 1990 |
Effects of untreated maternal hyperphenylalaninemia on the fetus: further study of families identified by routine cord blood screening.
Topics: Adolescent; Child; Child Development; Child, Preschool; Female; Fetal Blood; Humans; Intelligence; Longitudinal Studies; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects | 1990 |
Estimation of the isoleucine and aromatic amino acid requirements of pregnant swine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Female; Isoleucine; Phenylalanine; Pregnancy; Pregnancy, Animal; Random Allocation; Swine; Tyrosine | 1990 |
Microvillar enzymes in amniotic fluid. Considerations for the prenatal diagnosis of cystic fibrosis.
Topics: Alkaline Phosphatase; Amniotic Fluid; Congenital Abnormalities; Cystic Fibrosis; Female; Fetal Diseases; gamma-Glutamyltransferase; Homoarginine; Humans; Infant, Newborn; Isoenzymes; Phenylalanine; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prenatal Diagnosis; Risk | 1986 |
Protein turnover and growth of the rat brain from the foetus to old age.
Topics: Aging; Animals; Brain; DNA; Female; Fetus; Kinetics; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Rats; RNA | 1988 |
Quantitative analysis of alkaline phosphatases in serum and amniotic fluid: comparison of biochemical and immunologic assays.
Topics: Alkaline Phosphatase; Amniotic Fluid; Antibodies, Monoclonal; Bone and Bones; Chemical Precipitation; Female; Fetus; Homoarginine; Humans; Immunochemistry; Intestines; Isoenzymes; Kidney; Liver; Phenylalanine; Placenta; Pregnancy; Protein Denaturation | 1985 |
The effect of dietary protein quality and feeding level on milk secretion and mammary protein synthesis in the rat.
Topics: Animals; Dietary Proteins; DNA; Female; Food Deprivation; Lactation; Mammary Glands, Animal; Milk; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; RNA; Tritium | 1985 |
Maternal phenylketonuria.
Topics: Adolescent; Adult; Dietary Proteins; Female; Food, Fortified; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Nutritional Requirements; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1989 |
Maternal phenylketonuria and hyperphenylalaninemia: implications for medical practice in the United States.
Topics: Congenital Abnormalities; Female; Genetic Techniques; Genetic Testing; Humans; Obstetrics; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Registries; Syndrome; United States | 1989 |
Maternal PKU pre-conception treatment--the need for free prescriptions.
Topics: Female; Genetic Counseling; Humans; Infant, Newborn; Male; Midwifery; Phenylalanine; Phenylketonurias; Pregnancy | 1989 |
Branched chain amino acids improve complex maze learning in rat offspring prenatally exposed to hyperphenylalaninemia: implications for maternal phenylketonuria.
Topics: Amino Acids, Branched-Chain; Animals; Female; Learning; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1989 |
Maternal phenylketonuria.
Topics: Brain Diseases; Cohort Studies; Embryonic and Fetal Development; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 1989 |
Prenatal diagnosis of classic phenylketonuria by DNA analysis.
Topics: Deoxyribonuclease EcoRI; DNA; DNA Restriction Enzymes; Female; Fetal Blood; Genetic Markers; Humans; Infant, Newborn; Male; Pedigree; Phenotype; Phenylalanine; Phenylketonurias; Pregnancy; Prenatal Diagnosis | 1985 |
Proteases in human lenses and their possible significance.
Topics: Aminopeptidases; CD13 Antigens; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Exopeptidases; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lens, Crystalline; Leucyl Aminopeptidase; Lysine; Methionyl Aminopeptidases; Peptide Hydrolases; Phenylalanine; Pregnancy; Prolyl Oligopeptidases; Serine Endopeptidases | 1985 |
Aspartame. Review of safety issues. Council on Scientific Affairs.
Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats | 1985 |
Timing of strict diet in relation to fetal damage in maternal phenylketonuria. An international collaborative study by the MRC/DHSS Phenylketonuria Register.
Topics: Birth Weight; Congenital Abnormalities; Diet; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Gestational Age; Head; Humans; Infant, Newborn; International Cooperation; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Time Factors | 1987 |
Characteristics of histidine uptake by human placental microvillous membrane vesicles.
Topics: Aminoisobutyric Acids; Anions; Biological Transport, Active; Cations; Cysteine; Ethylmaleimide; Female; Gluconates; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Microvilli; Osmolar Concentration; Phenylalanine; Placenta; Pregnancy; Sodium; Temperature | 1989 |
Effects of phenylalanine loading on protein synthesis in the fetal heart and brain of rat: an experimental approach to maternal phenylketonuria.
Topics: Animals; Brain; Carbon Radioisotopes; Disease Models, Animal; Female; Fenclonine; Fetal Heart; Fetus; Leucine; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Polyribosomes; Pregnancy; Protein Biosynthesis; Rats; Rats, Inbred Strains; Urea | 1986 |
Relationships among maternal and fetal amino acid blood concentrations and amniotic fluid amino acid levels in pregnant rhesus monkeys.
Topics: Amino Acids; Amniotic Fluid; Animals; Female; Fenclonine; Fetal Blood; Macaca mulatta; Phenylalanine; Pregnancy | 1986 |
Experimental hyperphenylalaninemia in the pregnant guinea pig: possible phenylalanine teratogenesis and p-chlorophenylalanine embryotoxicity.
Topics: Animals; Embryonic and Fetal Development; Female; Fenclonine; Fetal Death; Guinea Pigs; Liver; Maternal-Fetal Exchange; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy | 1987 |
Structural determinants of ligand recognition by type I insulin-like growth factor receptors: use of semisynthetic insulin analog probes.
Topics: Affinity Labels; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Female; Humans; Insulin; Insulin-Like Growth Factor I; Molecular Weight; Phenylalanine; Placenta; Pregnancy; Proinsulin; Receptor, Insulin; Receptors, Somatomedin; Structure-Activity Relationship | 1988 |
Effects of hyperphenylalaninemia in the fetal stage on the postnatal development of fetal rat brain.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain; Discrimination Learning; Female; Gestational Age; Intellectual Disability; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Determination of kininase I and kininase II activities in human urine by high-performance liquid chromatography.
Topics: Carboxypeptidases; Chromatography, High Pressure Liquid; Female; Hippurates; Humans; Infant, Newborn; Lysine Carboxypeptidase; Peptidyl-Dipeptidase A; Phenylalanine; Pregnancy; Substrate Specificity | 1987 |
Maternal PKU syndrome in an exceptional family with unexpected PKU.
Topics: Adult; Child, Preschool; Female; Humans; In Vitro Techniques; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1987 |
Calcium-sensitive uptake of amino acids by human placental slices.
Topics: Amino Acids, Branched-Chain; Biological Transport; Calcium; Egtazic Acid; Female; Humans; In Vitro Techniques; Phenylalanine; Placenta; Pregnancy; Protein Synthesis Inhibitors; Trifluoperazine; Verapamil | 1988 |
Successful treatment of maternal phenylketonuria with a formula consisting of low phenylalanine peptide as a protein source.
Topics: Adult; Dietary Proteins; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1988 |
Changes in phenylalanine tolerance while monitoring the dietetic treatment of pregnant women suffering from hyperphenylalaninaemia.
Topics: Drug Tolerance; Female; Fetus; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications | 1988 |
The effects of maternal hyperphenylalaninemia on learning in mature rats.
Topics: Animals; Birth Weight; Female; Learning; Learning Disabilities; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Rats | 1988 |
Maternal phenylketonuria: successful outcome in four pregnancies treated prior to conception.
Topics: Child; Child, Preschool; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1988 |
[Changes in phenylalanine tolerance during the monitoring of diet therapy of pregnant women with phenylketonuria].
Topics: Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1988 |
Increased concentrations of tyrosine and phenylalanine in the cerebrospinal fluid as a possible reflection of related changes of the brain tissue in newborns with intra-uterine growth retardation.
Topics: Biomarkers; Brain; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Infant, Small for Gestational Age; Phenylalanine; Pregnancy; Reference Values; Tyrosine | 1988 |
Saccharin and aspartame. Are they safe to consume during pregnancy?
Topics: Aspartame; Aspartic Acid; Dipeptides; Female; Humans; Methanol; Phenylalanine; Pregnancy; Saccharin | 1988 |
The New England Maternal PKU Project: identification of at-risk women.
Topics: Adolescent; Adult; Child; Epidemiologic Methods; Female; Genetic Diseases, Inborn; Health; Humans; Maternal-Child Health Centers; Medical Records; New England; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnant Women; Risk Factors | 1988 |
[Is phenylalanine really inoffensive in the treatment of vitiligo?].
Topics: Female; Humans; Infant, Newborn; Phenylalanine; Pregnancy; Vitiligo | 1988 |
[Offspring of mothers with hyperphenylalaninemia treated with a low phenylalanine diet before conception and during pregnancy].
Topics: Birth Weight; Cephalometry; Child Development; Female; Humans; Infant, Newborn; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1988 |
Treatment of phenylketonuria with a formula consisting of low-phenylalanine peptide. A collaborative study.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Food, Formulated; Humans; Infant; Infant Food; Infant, Newborn; Peptides; Phenylalanine; Phenylketonurias; Pregnancy; Prognosis; Taste | 1987 |
[Maternal phenylketonuria].
Topics: Adult; Anthropometry; Birth Weight; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Time Factors | 1987 |
[Embryofetopathy caused by postnatally detected maternal phenylketonuria].
Topics: Adult; Diagnosis, Differential; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy | 1987 |
Maternal PKU: strategies for dietary treatment and monitoring compliance.
Topics: Adolescent; Adult; Female; Food, Formulated; Humans; Infant, Newborn; Male; Patient Compliance; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1986 |
Dietary and genetic therapy of inborn errors of metabolism: a summary.
Topics: Adult; Breast Feeding; Enzyme Therapy; Female; Genetic Engineering; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Psychomotor Performance; Zinc | 1986 |
Prenatal diagnosis of "dihydrobiopterin synthetase" deficiency, a variant form of phenylketonuria.
Topics: Alcohol Oxidoreductases; Amniocentesis; Amniotic Fluid; Biopterins; Child, Preschool; Female; Humans; Infant; Male; Neopterin; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pregnancy; Prenatal Diagnosis; Tyrosine | 1986 |
Consumption of aspartame by heterozygotes for phenylketonuria.
Topics: Aspartame; Dipeptides; Female; Fetal Diseases; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Pregnancy | 1987 |
Pre-conceptual dietary management for maternal phenylketonuria.
Topics: Adolescent; Adult; Contraception; Female; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1987 |
The safety of aspartame.
Topics: Aspartame; Dipeptides; Female; Humans; Intelligence; Maternal-Fetal Exchange; Phenylalanine; Pregnancy | 1987 |
Hydrolysis of phosphatidate by human placental alkaline phosphatase.
Topics: Alkaline Phosphatase; Female; Humans; Hydrolysis; Phenylalanine; Phosphatidic Acids; Placenta; Pregnancy; Sodium Fluoride | 1987 |
Summary report of an International Aspartame Workshop.
Topics: Animals; Aspartame; Biotransformation; Dipeptides; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy | 1987 |
Is it safe to consume aspartame during pregnancy? A review. Nutrition update.
Topics: Adolescent; Adult; Aspartame; Child; Child, Preschool; Dipeptides; Female; Humans; Infant; Lactation; Male; Methanol; Phenylalanine; Pregnancy | 1986 |
Implementation of a self-care approach in a pediatric interdisciplinary phenylketonuria (PKU) clinic.
Topics: Adolescent; Adult; Child; Child, Preschool; Dietary Proteins; Female; Humans; Male; Patient Care Planning; Phenylalanine; Phenylketonurias; Pregnancy; Self Care | 1986 |
Phenylalanine requirement of the lactating sow.
Topics: Amino Acids; Animals; Female; Lactation; Nutritional Requirements; Phenylalanine; Pregnancy; Swine | 1987 |
Prevention of fetal damage through dietary control of maternal hyperphenylalaninemia.
Topics: Adolescent; Animals; Child; Child, Preschool; Female; Fetal Diseases; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intellectual Disability; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1986 |
Characterization of tryptophan transport in human placental brush-border membrane vesicles.
Topics: Amino Acids; Azides; Biological Transport; Ethylmaleimide; Female; Humans; In Vitro Techniques; Kinetics; Microvilli; Phenylalanine; Placenta; Pregnancy; Sodium; Tryptophan | 1986 |
New England Maternal PKU Project: prospective study of untreated and treated pregnancies and their outcomes.
Topics: Adolescent; Adult; Female; Fetal Blood; Fetal Diseases; Humans; Infant, Newborn; Microcephaly; Patient Compliance; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Prognosis; Tyrosine | 1987 |
Women with phenylketonuria: successful management of pregnancy and implications.
Topics: Adolescent; Adult; Congenital Abnormalities; Female; Humans; Infant, Newborn; Intellectual Disability; Male; Microcephaly; New Zealand; Patient Education as Topic; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy in Adolescence; Time Factors | 1985 |
Outcome of pregnancy in the rat with mild hyperphenylalaninaemia and hypertyrosinaemia: implications for the management of "human maternal PKU".
Topics: Animals; Brain Diseases; Discrimination, Psychological; Disease Models, Animal; Female; Motor Activity; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Space Perception; Tyrosine | 1985 |
Maternal phenylketonuria and phenylalanine restricted diet. Studies of 7 pregnancies and of offsprings produced.
Topics: Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prognosis | 1985 |
Maternal PKU.
Topics: Birth Weight; Female; Fetal Blood; Humans; Infant, Newborn; Intelligence; Mass Screening; Maternal-Fetal Exchange; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1985 |
Maternal phenylketonuria. Committee on Genetics.
Topics: Female; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Risk | 1985 |
Protein turnover in the rat uterus during and after pregnancy.
Topics: Animals; Female; Phenylalanine; Pregnancy; Pregnancy, Animal; Protein Biosynthesis; Proteins; Rats; Tritium; Uterus | 1985 |
Preliminary report on inverse diurnal variation of phenylalanine: implications in maternal phenylketonuria.
Topics: Adult; Amino Acids; Circadian Rhythm; Female; Fetal Diseases; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1985 |
Biological and behavioural assessments of young rhesus monkeys after intrauterine exposure to high phenylalanine concentrations.
Topics: Animals; Disease Models, Animal; Female; Learning; Macaca mulatta; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1985 |
Fetomaternal placental transfer mechanisms of aromatic amino acids in Macaca mulatta.
Topics: Amino Acids; Animals; Female; Kinetics; Macaca mulatta; Maternal-Fetal Exchange; Phenylalanine; Pregnancy | 1985 |
Aromatic amino acid requirement of the lactating sow.
Topics: Animal Nutritional Physiological Phenomena; Animals; Female; Lactation; Phenylalanine; Pregnancy; Swine; Tyrosine | 1985 |
Protein turnover and cathepsin B activity in several individual tissues of foetal and senescent rats.
Topics: Aging; Animals; Cathepsin B; Cathepsins; Female; Fetus; Gestational Age; Male; Phenylalanine; Pregnancy; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1985 |
Lactation and phenylketonuria.
Topics: Adult; Amino Acids; Female; Humans; Infant, Newborn; Lactation; Milk, Human; Phenylalanine; Phenylketonurias; Pregnancy | 1985 |
Corticosteroid induced changes in plasma amino acids and thyroid activity in dairy cows treated early or late during lactation.
Topics: Adrenal Cortex Hormones; Amino Acids; Animals; Body Weight; Cattle; Dexamethasone; Female; Flumethasone; Glutamine; Glycerol; Iodine; Isoleucine; Lactation; Methionine; Phenylalanine; Pregnancy; Serine; Thyroid Function Tests; Thyroid Gland; Tyrosine; Urea; Valine | 1971 |
Birthweights in children with phenylketonuria and in their siblings.
Topics: Birth Weight; Body Height; Female; Gestational Age; Humans; Infant, Newborn; Intellectual Disability; Male; Mass Screening; Norway; Parity; Phenylalanine; Phenylketonurias; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Uterine Hemorrhage | 1972 |
Aminoacid composition of amniotic fluid in central-nervous-system malformations.
Topics: Amino Acids; Amniocentesis; Amniotic Fluid; Anencephaly; Female; Fetal Death; Humans; Infant, Newborn; Isoleucine; Leucine; Methionine; Phenylalanine; Pregnancy; Respiratory Distress Syndrome, Newborn; Spinal Dysraphism; Tyrosine | 1973 |
Characterization of two HeLa sublines: TCRC-1 produces Regan isoenzyme and TCRC-2, non-Regan isoenzyme.
Topics: Alkaline Phosphatase; Arginine; Carcinoembryonic Antigen; Cell Survival; Chromosomes; Drug Stability; Female; Glucuronidase; HeLa Cells; Hot Temperature; Humans; Immunodiffusion; Isoenzymes; Phenylalanine; Placenta; Prednisolone; Pregnancy; Staining and Labeling | 1974 |
Enzymes involved in phenylalanine metabolism in the human foetus and child.
Topics: Child; Child, Preschool; Female; Fetus; Humans; Infant; Infant, Newborn; Ketoglutaric Acids; Ketone Oxidoreductases; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic; Pyruvates; Transaminases; Tyrosine Transaminase | 1973 |
Characterization of newborn leukocyte alkaline phosphatase.
Topics: Alkaline Phosphatase; Arginine; Binding Sites; Blood; Child; Child, Preschool; Chromatography; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; Humans; Infant, Newborn; Leukocytes; Neuraminidase; Phenylalanine; Pregnancy; Umbilical Cord; Zinc | 1973 |
Learning in monkeys fed elevated amino acid diets.
Topics: Alanine; Amino Acids; Animals; Diet; Discrimination Learning; Female; Food; Glycine; Haplorhini; Histidine; Humans; Learning; Macaca; Monkey Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Problem Solving; Reward; Tryptophan; Tyrosine | 1973 |
Evidence for two types of phosphorylation of proteins.
Topics: Amino Acids; Animals; Barium; Blood Proteins; Carbon Isotopes; Caseins; Chromatography; Cycloheximide; Ethionine; Female; Hydroxides; Kidney; Lactation; Liver; Mammary Glands, Animal; Metabolism; Phenylalanine; Phosphatidylethanolamines; Phosphorus; Phosphorus Isotopes; Pregnancy; Proteins; Puromycin; Rats; RNA, Transfer; Tryptophan | 1969 |
Induction of pseudopregnancy in rats by p-chlorophenylalanine.
Topics: Animals; Body Weight; Brain; Female; Fenclonine; Norepinephrine; Organ Size; Ovary; Phenylalanine; Pregnancy; Pregnancy, Animal; Pseudopregnancy; Rats; Serotonin; Uterus; Vaginal Smears | 1971 |
p-chlorophenylalanine facilitates copulatory behaviour in male rats.
Topics: Analysis of Variance; Animals; Appetitive Behavior; Copulation; Ejaculation; Estradiol; Estrus; Female; Fenclonine; Male; Phenylalanine; Pregnancy; Rats; Sexual Behavior, Animal | 1971 |
Effect of para-chlorophenylalanine on the growth and development of the fetal, neonatal, and adult rat.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Feeding Behavior; Female; Fenclonine; Fetus; Gestational Age; Male; Organ Size; Phenylalanine; Pregnancy; Rats; Time Factors | 1970 |
Reduced 5-hydroxyindole synthesis reduces postnatal brain growth in rats.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Body Weight; Brain; Brain Chemistry; Drug Interactions; Female; Fenclonine; Hydroxylation; Indoles; Male; Nerve Tissue Proteins; Organ Size; Phenylalanine; Postpartum Period; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1972 |
Effect of vitamin B 6 on phenylalanine metabolism in the brain of normal and p-chlorophenylalanine-treated rats.
Topics: Animals; Brain; Carbon Isotopes; Female; Fenclonine; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Phenylalanine; Phenylketonurias; Pregnancy; Pyridoxamine; Pyridoxine; Rats; Spectrometry, Fluorescence; Time Factors; Tritium | 1972 |
Experimental maternal hyperphenylalaninemia: disaggregation of fetal brain ribosomes.
Topics: Animals; Brain; Brain Chemistry; Centrifugation, Density Gradient; Female; Fenclonine; Fetus; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Polyribosomes; Pregnancy; Rats; Tryptophan; Tyrosine | 1973 |
Behavioral effects of experimental maternal hyperphenylalaninemia.
Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Exploratory Behavior; Female; Fenclonine; Fetus; Gestational Age; Humans; Maternal-Fetal Exchange; Motor Activity; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Reinforcement Schedule; Social Behavior | 1973 |
Experimental maternal hyperphenylalaninemia: biochemical effects and offspring development.
Topics: Aggression; Animals; Animals, Newborn; Body Weight; Brain; Brain Chemistry; Disease Models, Animal; Embryonic and Fetal Development; Female; Fenclonine; Growth; Humans; Maternal Behavior; Maternal-Fetal Exchange; Organ Size; Phenylalanine; Phenylketonurias; Pregnancy; Rats | 1974 |
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine; Magnesium; Methionine; Niacinamide; Obstetric Labor Complications; Phenylalanine; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Rheumatic Heart Disease; Sodium; Tryptophan; Tyrosine; Valine; Vitamin E | 1974 |
tRNA and aminoacyl-tRNA synthetases during differentiation and various functional states of the mammary gland.
Topics: Amino Acyl-tRNA Synthetases; Animals; Carbon Isotopes; Cattle; Chromatography; Female; Glutamates; Glycine; Kinetics; Lactation; Leucine; Mammary Glands, Animal; Methionine; Methylation; Periodic Acid; Phenylalanine; Pregnancy; Rabbits; RNA, Transfer; Serum Albumin; Silicon Dioxide | 1971 |
Effect of phenylalanine and p-chlorophenylalanine administration on the development of rat brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.
Topics: Age Factors; Animals; Body Weight; Brain; Cerebellum; Electron Transport Complex IV; Female; Fenclonine; Hexokinase; Nucleotides, Cyclic; Organ Size; Phenylalanine; Phosphoric Monoester Hydrolases; Pregnancy; Rats; Tyrosine | 1974 |
Studies upon the mechanism of reserpine-induced arrest in egg transport in the mouse oviduct. II. Comparative effects of some agents with actions on smooth muscle and tissue amines.
Topics: Amphetamine; Animals; Atropine; Catecholamines; Chlorpromazine; Ethanolamines; Female; Guanethidine; Hypothermia; Isoproterenol; Mice; Muscle, Smooth; Nerve Endings; Oviducts; Ovum; Peripheral Nerves; Phentolamine; Phenylalanine; Pregnancy; Reserpine; Sympathetic Nervous System; Temperature; Tetrabenazine | 1969 |
Thin-layer chromatographic screening of amino acids in plasma and urine of newborns.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Blood Proteins; Chromatography, Thin Layer; Female; Glycine; Homocysteine; Humans; Indicators and Reagents; Infant, Newborn; Infant, Premature; Lysine; Methionine; Phenylalanine; Pregnancy; Proteinuria; Tyrosine; Ultrafiltration | 1974 |
Feto-maternal amino acid metabolism.
Topics: Amino Acids; Amniocentesis; Amniotic Fluid; Arginine; Autoanalysis; Carnosine; Ethanolamines; Female; Fetus; Gestational Age; Glycine; Humans; Hydroxyproline; Infant, Newborn; Lysine; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Serine; Tyrosine; Umbilical Cord | 1974 |
Fetal development: the effects of maturation on in vitro protein synthesis by mouse brain tissue.
Topics: Aging; Animals; Animals, Newborn; Arginine; Brain; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Deoxycholic Acid; Female; Fetus; Gestational Age; In Vitro Techniques; Magnesium; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phenylalanine; Polyribosomes; Pregnancy; Time Factors | 1974 |
Observations on chemotherapy of granulosa cell carcinomas and malignant ovarian teratomas.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Cyclophosphamide; Dactinomycin; Fallopian Tubes; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Hysterectomy; Middle Aged; Ovarian Neoplasms; Phenylalanine; Pregnancy; Teratoma; Vincristine | 1974 |
Maternal hyperphenylalaninemia induced experimentally: decreased incorporation of 14C-leucine into protein in the brain of the fetus.
Topics: Administration, Oral; Animals; Brain; Carbon Radioisotopes; Female; Fetus; Injections, Intraperitoneal; Leucine; Liver; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats | 1974 |
Maternal phenylketonuria: a family with seven mentally retarded siblings.
Topics: Abnormalities, Multiple; Birth Weight; Dwarfism; Electroencephalography; Female; Humans; Intellectual Disability; Intelligence; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tetralogy of Fallot | 1974 |
Serotonin deficiency in experimental hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Animals; Biphenyl Compounds; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dopa Decarboxylase; Female; Humans; Hydroxyindoleacetic Acid; Oxazoles; Pargyline; Phenethylamines; Phenylalanine; Phenylketonurias; Pregnancy; Pyridoxal; Pyridoxamine; Pyridoxine; Rats; Serotonin; Spectrometry, Fluorescence; Time Factors; Tritium | 1974 |
Mechanisms in protein synthesis. 8. Competitive inhibition of polyphenylalanine synthesis by non-poly (U)-coded aminoacyl-tRNAs.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Binding, Competitive; Centrifugation, Density Gradient; Escherichia coli; Female; Fusidic Acid; Humans; Kinetics; Palatine Tonsil; Peptide Biosynthesis; Peptide Elongation Factors; Phenylalanine; Placenta; Pregnancy; Ribosomes; RNA, Transfer; Tritium | 1972 |
Identification and characterization of Moraxella phenylpyruvica.
Topics: Adult; Aged; Bartholin's Glands; Bile; Child; Child, Preschool; Culture Media; Cysts; DNA, Bacterial; Female; Gastroenteritis; Humans; Infant; Leg Ulcer; Male; Microbial Sensitivity Tests; Moraxella; Phenylalanine; Pre-Eclampsia; Pregnancy; Pressure Ulcer; Pulmonary Fibrosis; Urease; Vaginal Diseases; Vulvovaginitis | 1972 |
[Blood-brain barrier and placental barrier for various amino acids in the mouse (whole body autoradiography studies)].
Topics: Alanine; Amino Acids; Animals; Autoradiography; Blood-Brain Barrier; Cell Membrane Permeability; Female; Glycine; Lysine; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenylalanine; Pregnancy; Serine; Tritium; Tyrosine | 1972 |
[2 new cases of microcephalic children with intrauterine growth retardation born of phenylketonuric mothers].
Topics: Birth Weight; Chromatography, Ion Exchange; Female; Growth Disorders; Humans; Infant; Male; Mental Disorders; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1972 |
Protein synthesis in different hypothalamic areas during the sexual cycle in rats: influence of castration.
Topics: Animals; Animals, Newborn; Castration; Estrus; Female; Hypothalamus; Ovary; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; Testosterone; Tritium | 1972 |
[Karyometric study of thyroid follicular cells in phenylketonuric animals].
Topics: Animals; Cell Nucleus; Female; Humans; Infant, Newborn; Karyometry; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Thyroid Gland; Time Factors | 1972 |
[The significance of phenylalanine-alpha-ketoglutarate transaminase for the qualification of boar semen (author's transl)].
Topics: Animals; Female; Fertility; Insemination, Artificial; Ketoglutaric Acids; Male; Phenylalanine; Pregnancy; Pregnancy, Animal; Semen; Spermatozoa; Swine; Temperature; Transaminases | 1972 |
Clinical significance of tyrosinemia of prematurity.
Topics: Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Child Development; Chromatography, Paper; Diet Therapy; Fatigue; Feeding Behavior; Female; Growth Disorders; Humans; Infant, Newborn; Infant, Premature, Diseases; Intelligence; Intelligence Tests; Phenylalanine; Pregnancy; Pregnancy Complications; Tyrosine | 1973 |
Profiles of alkaline phosphatase isoenzymes in serum using cellulose acetate electrophoresis and organ-specific inhibitors.
Topics: ABO Blood-Group System; Acetates; Alkaline Phosphatase; Biliary Tract Diseases; Bilirubin; Bone and Bones; Cellulose; Electrophoresis; Enzyme Repression; Female; Humans; Indicators and Reagents; Isoenzymes; Liver; Liver Diseases; Male; Parity; Phenylalanine; Placenta; Pregnancy; Urea | 1973 |
Normal development in an infant of a mother with phenylketonuria.
Topics: Black People; Child Development; Female; Humans; Infant; Intelligence; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Pregnancy Complications; Tyrosine | 1973 |
Effects of oral contraceptives and obesity on carrier tests for phenylketonuria.
Topics: Adult; Contraceptives, Oral; Fasting; Female; Heterozygote; Humans; Menstruation; Middle Aged; Obesity; Ovulation; Phenylalanine; Phenylketonurias; Pregnancy; Temperature; Time Factors; Tyrosine | 1973 |
Role of methionine in the initiation of the biosynthesis of bovine proinsulin.
Topics: Adsorption; Amino Acid Sequence; Amino Acids; Animals; Antibodies; Cattle; Chromatography, Ion Exchange; Chromatography, Thin Layer; Female; Fetus; Guinea Pigs; In Vitro Techniques; Insulin; Iodine Isotopes; Leucine; Methionine; Microsomes; Pancreas; Peptides; Phenylalanine; Pregnancy; Proinsulin; Sulfur Isotopes; Time Factors; Tritium | 1973 |
Unrecognized adult phenylketonuria. Implications for obstetrics and psychiatry.
Topics: Adult; Child; Chlorides; Female; Heterozygote; Humans; Intellectual Disability; Intelligence; Iron; Male; Middle Aged; Pedigree; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Pregnancy Complications; Psychotic Disorders | 1973 |
Risk of fetal damage in maternal phenylketonuria.
Topics: Brain Damage, Chronic; Diet Therapy; Female; Fetal Diseases; Humans; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1973 |
Increased "reproductive casualty" in heterozygotes for phenylketonuria.
Topics: Abortion, Spontaneous; Birth Weight; Delivery, Obstetric; Embryonic and Fetal Development; Female; Fetal Death; Heterozygote; Humans; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Labor Presentation; Male; Obstetric Labor Complications; Parity; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Uterine Hemorrhage | 1973 |
Anomalous phenylalanine loading responses in relation to cleft lip and cleft palate.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Chromosomes, Human, 13-15; Cleft Lip; Cleft Palate; Female; Humans; Infant, Newborn; Karyotyping; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Time Factors; Trisomy; Tyrosine | 1973 |
Similarities between pyruvate kinase from human placenta and tumours.
Topics: Adenosine Triphosphate; Alanine; Carcinoma; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Starch Gel; Female; Fructosephosphates; Humans; Intestinal Neoplasms; Isoenzymes; Jejunum; Kinetics; Lung Neoplasms; Male; Molecular Weight; Organ Specificity; Phenylalanine; Placenta; Pregnancy; Pyruvate Kinase; Serine; Stomach Neoplasms | 1973 |
[Hyperphenylalaninemia in the neonatal period].
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography; Diet; Female; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy | 1973 |
Classic phenylketonuria: heterozygote detection during pregnancy.
Topics: Adolescent; Adult; Analysis of Variance; Female; Genetic Counseling; Genotype; Heterozygote; Homozygote; Humans; Infant, Newborn; Male; Mathematics; Microchemistry; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1973 |
The effects of p-DL-fluorophenylalanine on chromosome movement and cytokinesis of human amnion cells in culture.
Topics: Amnion; Cell Division; Cells, Cultured; Chromosomes; Female; Fluorine; Humans; Meiosis; Mitosis; Phenylalanine; Photography; Pregnancy; Time Factors | 1973 |
A study of phenylketonuric sibs.
Topics: Abortion, Spontaneous; Chromatography, Paper; Epilepsy; Female; Gene Frequency; Humans; Intellectual Disability; Male; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy | 1973 |
Letter: Management of women with phenylketonuria.
Topics: Female; Genetic Counseling; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy | 1974 |
The isoenzymes of alkaline phosphatase in sera of normal pregnancy at term.
Topics: Adult; Alkaline Phosphatase; Arginine; Blood Protein Electrophoresis; Bone and Bones; Cellulose; Densitometry; Female; Gestational Age; Hot Temperature; Humans; Intestines; Isoenzymes; Liver; Maternal Age; Parity; Phenylalanine; Placenta; Pregnancy; Urea | 1974 |
Letter: Screening for phenylketonuria.
Topics: Diet; Female; Heterozygote; Humans; Infant, Newborn; Mass Screening; Phenylalanine; Phenylketonurias; Pregnancy | 1974 |
A sensitive polyacrylamide disc gel method for detection of proteinases.
Topics: Animals; Caseins; Chlorine; Chymotrypsin; Diffusion; Electrophoresis, Disc; Embryo, Mammalian; Evaluation Studies as Topic; Female; Hemoglobins; Hydrogen-Ion Concentration; Lysine; Male; Methods; Mice; Microchemistry; Peptide Hydrolases; Phenylalanine; Pregnancy; Protein Denaturation; Semen; Solubility; Spectrophotometry, Ultraviolet; Tosyl Compounds; Trypsin | 1974 |
Baby of a phenylketonuric mother. Inferences drawn from a single case.
Topics: Brain Damage, Chronic; Child, Preschool; Diet Therapy; Female; Fetus; Humans; Intelligence; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1974 |
The role of heterozygosity of women with respect to the phenylketonuria gene in the origin of spontaneous abortions and disturbances of intrauterine fetal development.
Topics: Abortion, Spontaneous; Bone and Bones; Chromatography, Paper; Congenital Abnormalities; Female; Fetal Diseases; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Pregnancy | 1974 |
Arterial mesenchyme and arteriosclerosis. Enzymic vs non-enzymic factors in the deterioration of connective tissue.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Blood Platelets; Cattle; Child; Collagen; Connective Tissue; Culture Techniques; Elastic Tissue; Elastin; Female; Fluorescence; Humans; Leukocytes; Male; Middle Aged; Pancreatic Elastase; Phenylalanine; Pregnancy; Proteins; Solubility; Tyrosine; Ultraviolet Rays; X-Ray Diffraction | 1974 |
A simplified accurate method for detecting bacteriuria.
Topics: Bacteriological Techniques; Bacteriuria; Female; Humans; Nitrites; Phenylalanine; Pregnancy; Pregnancy Complications, Infectious; Urine | 1968 |
"Fetal PKU:" the effect of maternal hyperphenylalaninemia during pregnancy in the rhesus monkey (Macaca mulatta).
Topics: Amino Acids; Animals; Animals, Newborn; Birth Weight; Diet; Female; Fetal Diseases; Haplorhini; Humans; Intellectual Disability; Learning; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Serine; Tyrosine | 1968 |
Purification and molecular properties of placental and intestinal alkaline phosphatases.
Topics: Alkaline Phosphatase; Animals; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Crystallography; Electrophoresis; Escherichia coli; Female; Glucuronidase; Hemagglutination, Viral; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Intestines; Isoenzymes; Kinetics; Methods; Molecular Weight; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Rats; Thermodynamics; Time Factors; Ultracentrifugation | 1969 |
Placental alkaline phosphatase and pregnancy.
Topics: Alkaline Phosphatase; Animals; Antibodies; Bone and Bones; Dialysis; Edetic Acid; Electrophoresis; Female; Guinea Pigs; Horses; Hot Temperature; Intestines; Kinetics; Liver; Magnesium; Mice; Phenylalanine; Placenta; Pregnancy; Protein Denaturation; Rabbits; Rats; Sheep; Species Specificity; Urea | 1969 |
[Biosynthesis of proteins in the rabbit placenta].
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Female; Microsomes; Phenylalanine; Placenta; Pregnancy; Protein Biosynthesis; Rabbits; Ribosomes; RNA; RNA, Messenger; RNA, Transfer; Uracil Nucleotides | 1970 |
Differential reinforcement of latency (DRL) in phenylketonuric monkeys.
Topics: Animals; Conditioning, Operant; Diet; Disease Models, Animal; Feeding Behavior; Female; Frustration; Haplorhini; Humans; Macaca; Phenylalanine; Phenylketonurias; Pregnancy; Reaction Time; Reinforcement, Psychology; Reward | 1970 |
Tyrosinemia induced by a pyridoxine antagonist, desoxypyridoxine.
Topics: Depression, Chemical; Female; In Vitro Techniques; Lactation; Liver; Liver Cirrhosis; Male; Metabolic Diseases; Metabolism; Methanol; Phenylalanine; Pregnancy; Pyridines; Pyridoxine; Tyrosine; Urine; Vitamin B 6 Deficiency | 1972 |
Chemical modification of alkaline phosphatases. The effects of several treatments on human placental alkaline phosphatase isoenzymes.
Topics: Acetates; Acylation; Alkaline Phosphatase; Anhydrides; Chemical Phenomena; Chemistry; Electrophoresis; Ethylmaleimide; Female; Humans; Hydrogen-Ion Concentration; Intestine, Small; Isoenzymes; Kinetics; Nitro Compounds; Phenylalanine; Placenta; Pregnancy; Succinates | 1972 |
Quality control of an automated differential isoenzyme assay of alkaline phosphatase, with use of L-phenylalanine inhibition.
Topics: Alkaline Phosphatase; Autoanalysis; Drug Stability; Female; Hot Temperature; Humans; Isoenzymes; Methods; Phenols; Phenylalanine; Phosphoric Acids; Placenta; Pregnancy; Quality Control | 1972 |
Semiquantitation of leucine, isoleucine, and valine by thin-layer chromatography in management of maple-syrup urine diseases.
Topics: Amniotic Fluid; Ascitic Fluid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Diet Therapy; Evaluation Studies as Topic; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methods; Peritoneal Dialysis; Phenylalanine; Pregnancy; Valine | 1972 |
Amniotic fluid amino acids in maternal phenylketonuria.
Topics: Adult; Amino Acids; Amniotic Fluid; Diet Therapy; Female; Gestational Age; Humans; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1972 |
Problems in the biochemical detection of heterozygotes for phenylketonuria.
Topics: Autoanalysis; Chromatography, Ion Exchange; Female; Heterozygote; Humans; Methods; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1972 |
The problem of maternal phenylketonuria.
Topics: Animals; Diet Therapy; Female; Humans; Infant, Newborn; Intelligence Tests; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Premarital Examinations; Prenatal Care; Rats | 1972 |
Imidazole: an inhibitor of L-phenylalanine-insensitive alkaline phosphatases of tissues other than intestine and placenta.
Topics: Alkaline Phosphatase; Aminocaproates; Animals; Binding Sites; Bone and Bones; Brain; Cattle; Columbidae; Female; Guanidines; Histidine; Horses; Humans; Imidazoles; Intestines; Kidney; Liver; Lung; Organ Specificity; Phenylalanine; Placenta; Pregnancy; Rabbits; Rats; Species Specificity; Spleen; Zinc | 1972 |
[Amino acid metabolism and mental retardation].
Topics: Diet Therapy; Female; Homocystinuria; Humans; Intellectual Disability; Intelligence; Male; Methionine; Phenylalanine; Phenylketonurias; Pregnancy; Pyridoxine | 1972 |
Separation of isoenzymes of alkaline phosphatase by substrate-gel imprint after electrophoresis on cellulose acetate.
Topics: Alkaline Phosphatase; Bile; Bone and Bones; Diazonium Compounds; Drug Stability; Duodenum; Electrophoresis; Female; Gallbladder; Hot Temperature; Humans; Infant, Newborn; Isoenzymes; Kidney; Liver; Liver Diseases; Methods; Naphthols; Phenylalanine; Phosphoric Acids; Placenta; Pregnancy; Urea | 1972 |
Phenylketonuria and the obstetrician.
Topics: Abnormalities, Multiple; Abortion, Therapeutic; Adolescent; Adult; Birth Weight; Child; Child, Preschool; Diet Therapy; Eugenics; Family Planning Services; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Iowa; Mass Screening; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1972 |
Amino acids in amniotic fluid: changes in concentrations during the first half of pregnancy.
Topics: Abortion, Therapeutic; Adult; Alanine; Amino Acids; Amniotic Fluid; Arginine; Chromatography, Ion Exchange; Female; Gestational Age; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Serine; Tyrosine; Valine | 1972 |
The effect of maternal amino acid imbalance on fetal cerebral polyribosomes.
Topics: Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Cerebral Cortex; Female; Fetus; Isotonic Solutions; Leucine; Maternal-Fetal Exchange; Microscopy, Electron; Microsomes; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; Tryptophan | 1972 |
Studies on the formation of transfer ribonucleic acid-ribosome complexes. XIV. Preparation of ribosomes from human placenta: characteristics and requirements of aminoacyl-tRNA binding.
Topics: Adenine Nucleotides; Carbon Isotopes; Depression, Chemical; Female; Humans; Kinetics; Lysine; Magnesium; Peptide Biosynthesis; Phenylalanine; Placenta; Polynucleotides; Potassium; Pregnancy; Quaternary Ammonium Compounds; Ribosomes; RNA, Transfer; Temperature; Templates, Genetic; Tritium; Tromethamine; Uracil Nucleotides | 1972 |
Maternal hyperphenylalaninaemia in the normal and phenylketonuric mother and its influence on maternal plasma and fetal fluid amino acid concentrations.
Topics: Adult; Amino Acids; Amniotic Fluid; Female; Fetus; Humans; Hysterectomy; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1972 |
A comparison between the phosphastrate and phenyl phosphate methods of alkaline phosphatase assay.
Topics: Adolescent; Adult; Alkaline Phosphatase; Female; Humans; Infant; Intestines; Isoenzymes; Male; Phenylalanine; Phosphates; Pregnancy; Tissue Extracts | 1972 |
[Delayed intrauterine growth with microcephaly in 3 children born of a hyperphenylalaninemic mother].
Topics: Abortion, Spontaneous; Adult; Child; Child, Preschool; Congenital Abnormalities; Diet Therapy; Female; Fetal Diseases; Growth Disorders; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Microcephaly; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications, Hematologic | 1972 |
Hyperphenylalaninemia and pregnancy.
Topics: Child; Female; Humans; Intelligence Tests; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1972 |
[Child of a mother with hyperphenylalaninemia].
Topics: Autoanalysis; Female; Humans; Infant, Newborn; Male; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1972 |
[Beef brain alkaline phosphatase: role of magnesium on the action of L-phenylalanine and other amino acids].
Topics: Alanine; Alkaline Phosphatase; Amino Acids; Aminocaproates; Animals; Binding Sites; Brain; Cattle; Chemical Phenomena; Chemistry; Enzyme Activation; Female; Humans; Hydrogen-Ion Concentration; Intestines; Isoleucine; Kinetics; Leucine; Magnesium; Molecular Weight; Phenylalanine; Placenta; Pregnancy; Serine; Stereoisomerism; Tryptophan | 1971 |
Mental retardation in four offspring of a hyperphenylalaninemic mother.
Topics: Adolescent; Adult; Child; Child Development; Diet; Female; Humans; Intellectual Disability; Intelligence Tests; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Care | 1971 |
Developmental changes in amino acid concentrations in human amniotic fluid: abnormal findings in maternal phenylketonuria.
Topics: Adult; Amino Acids; Amniotic Fluid; Chromatography; Congenital Abnormalities; Female; Fetal Diseases; Gestational Age; Humans; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1971 |
Biochemical studies of the placental alkaline phosphatase.
Topics: Alkaline Phosphatase; Bone and Bones; Colorimetry; Electrophoresis; Female; Gels; Hot Temperature; Humans; Intestinal Mucosa; Isoenzymes; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Starch | 1971 |
Phenylketonuria.
Topics: Child; Diet Therapy; Female; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Pregnancy Complications | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Placental transport of phenylalanine in the rat: maternal and fetal metabolism.
Topics: Animals; Diet Therapy; Fasting; Female; Fetus; Humans; Intellectual Disability; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Placenta; Pregnancy; Pregnancy Complications; Rats | 1971 |
Detection of phenylketonuric heterozygotes.
Topics: Chromatography, Ion Exchange; Female; Heterozygote; Humans; Indicators and Reagents; Methods; Phenylalanine; Phenylketonurias; Population Surveillance; Pregnancy; Tyrosine | 1971 |
Postnatal effects on some behavioral and neural parameters in mice treated with -2-thienylalanine in utero.
Topics: Animals; Body Weight; Brain; Cell Differentiation; Central Nervous System Diseases; Female; Humans; Learning Disabilities; Mice; Organ Size; Phenylalanine; Pregnancy; Seizures; Sound | 1971 |
Ontogenesis of phenylalanine and tryptophan hydroxylation in rat brain and liver.
Topics: Animals; Animals, Newborn; Brain; Carbon Isotopes; Chromatography; Female; Fetus; Injections, Intraperitoneal; Injections, Spinal; Liver; Mixed Function Oxygenases; Phenylalanine; Pregnancy; Rats; Tryptophan; Tyrosine | 1971 |
Automated differential isoenzyme analysis. II. The fractionation of serum alkaline phosphatases into "liver", "intestinal" and "other" components.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Arginine; Autoanalysis; Bone and Bones; Child; Child, Preschool; Drug Stability; Electrophoresis; Female; Hot Temperature; Humans; Intestines; Isoenzymes; Liver; Methods; Middle Aged; Phenylalanine; Placenta; Pregnancy | 1971 |
The protein-synthesizing activity of ribosomes isolated from the mammary gland of lactating and pregnant guinea pigs.
Topics: Albumins; Animals; Bile Acids and Salts; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Cyanogen Bromide; Female; Guinea Pigs; In Vitro Techniques; Lactation; Leucine; Mammary Glands, Animal; Phenylalanine; Polynucleotides; Pregnancy; Pregnancy, Animal; Protein Biosynthesis; Puromycin; Ribosomes; Tritium; Ultracentrifugation | 1971 |
Time sequences of action of oestrogen on nucleic acid and protein synthesis in the uterus and blastocyst during delayed implantation in the rat.
Topics: Animals; Cytidine; DNA; Embryo Implantation; Estrogens; Female; Nucleic Acids; Ovum; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; RNA; Thymidine; Time Factors; Tritium; Uterus | 1971 |
Differences in the ribosomes prepared from lactating and non-lactating bovine mammary gland.
Topics: Ammonium Chloride; Animals; Cattle; Centrifugation, Density Gradient; Female; Lactation; Liver; Mammary Glands, Animal; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; RNA, Transfer; Sucrose; Time Factors; Tritium; Uracil Nucleotides | 1971 |
Amino acid transport and mental retardation.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Benzyl Compounds; Biological Transport; Brain; Brain Chemistry; Diet; Female; Fetus; Gestational Age; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Time Factors | 1971 |
The effects of L-phenylalanine and phenylpyruvate on glycolysis in rat cerebral cortex.
Topics: Adenosine Triphosphate; Age Factors; Animals; Animals, Newborn; Brain; Cerebral Cortex; Female; Glucose; Glycolysis; Hexosephosphates; Humans; L-Lactate Dehydrogenase; Lactates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Phosphoenolpyruvate; Pregnancy; Pyruvate Kinase; Pyruvates; Rats | 1971 |
The effects of phenylpyruvate and hyperphenylalaninemia on incorporation of (6- 3 H)glucose into macromolecules of slices of rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Diet; DNA; Female; Fetus; Gestational Age; Glucose; Humans; Lipids; Macromolecular Substances; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; RNA; Tritium | 1971 |
Inhibition of spontaneous development of hyperplastic alveolar nodules and mammary tumors in C3H mice fed phenylalanine-deficient diets.
Topics: Animals; Body Weight; Deficiency Diseases; Diet; Estrus; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Ovary; Phenylalanine; Pregnancy; Time Factors | 1971 |
Nucleic acids and protein synthesis in the rat embryos and uterus in the preimplantation stages.
Topics: Animals; Autoradiography; DNA; Embryo Implantation; Embryo, Mammalian; Female; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; RNA; Thymidine; Uridine; Uterus | 1971 |
Microcephaly and mental retardation in offspring of a mother with phenylketonuria.
Topics: Child, Preschool; Female; Humans; Infant; Intellectual Disability; Male; Microcephaly; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Seizures | 1971 |
Effect of vitamin B 6 on blood 5-hydroxytryptamine concentration.
Topics: Animals; Animals, Newborn; Birth Weight; Body Weight; Brain; Carboxy-Lyases; Desoxycorticosterone; Diet; Female; Fetus; Humans; In Vitro Techniques; Indoleacetic Acids; Infant; Infant, Newborn; Kidney; Liver; Phenylalanine; Phenylketonurias; Postpartum Period; Pregnancy; Pyridoxine; Rats; Serotonin; Tryptophan; Tyrosine; Umbilical Cord; Vitamin B 6 Deficiency | 1969 |
The effect of parachlorophenylalanine on the behaviour of cats.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cats; Estrus; Female; Male; Phenylalanine; Pregnancy; Sex Factors; Sexual Behavior, Animal; Skin; Sleep; Sleep Deprivation | 1970 |
Maternal phenylalanine deprivation in the rat. Enzymatic and cellular liver changes in the offspring.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Body Weight; Deficiency Diseases; Deoxyribonucleases; Diet; Female; Histocytochemistry; Lactation; Liver; Microscopy, Electron; Oxygenases; Phenylalanine; Pregnancy; Pregnancy Complications; Rats; Tyrosine | 1969 |
Solid-phase syntheis and some pharmacological properties of [8-phenylalanine]-oxytocin.
Topics: Amino Acids; Animals; Anura; Biological Assay; Chemical Phenomena; Chemistry; Chickens; Chromatography, Gel; Depression, Chemical; Dextrans; Diuresis; Female; Lactation; Magnesium; Methods; Oxytocin; Peptides; Phenylalanine; Pituitary Gland; Pituitary Hormones, Posterior; Pregnancy; Rabbits; Rats; Sharks; Urinary Bladder; Uterus; Vasomotor System | 1969 |
Maternal phenylketonuria. Course of two pregnancies.
Topics: Adult; Amniotic Fluid; Birth Weight; Chromatography; Female; Growth; Heart Defects, Congenital; Hemorrhage; Humans; Infant, Newborn; Intellectual Disability; Lung; Lymphangiectasis; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine; Umbilical Cord; Vagina | 1969 |
Epidemiological considerations on maternal hyperphenylalaninemia.
Topics: Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Intelligence Tests; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1970 |
Intelligent, small for dates baby born to oligophrenic phenylketonuric mother after low phenylalanine diet during pregnancy.
Topics: Adult; Birth Weight; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Intelligence; Intelligence Tests; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine; Umbilical Arteries | 1970 |
Inhibition of alkaline phosphatase by L-phenylalanine.
Topics: Alkaline Phosphatase; Female; Humans; Hydrogen-Ion Concentration; Magnesium; Phenylalanine; Placenta; Pregnancy; Stereoisomerism | 1970 |
A study of the alkaline phosphatase activity in some commercial quality control sera with p-nitrophenyl phosphate and phenyl phosphate substrates.
Topics: Alkaline Phosphatase; Animals; Blood; Cattle; Drug Stability; Electrophoresis; Female; Gels; Hot Temperature; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Isoenzymes; Kidney; Nitrophenols; Phenylalanine; Phosphoric Acids; Placenta; Pregnancy; Protein Denaturation | 1970 |
Use of p-chlorophenylalanine to induce a phenylketonuric-like condition in rats.
Topics: Animals; Body Weight; Brain; Disease Models, Animal; Female; Humans; Intellectual Disability; Learning; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Serotonin; Swimming | 1970 |
Characterization of placental alkaline phosphatase from the rabbit, guinea pig, mouse and hamster.
Topics: Alkaline Phosphatase; Animals; Cricetinae; Drug Stability; Electrophoresis; Female; Guinea Pigs; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mice; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Rabbits; Species Specificity | 1970 |
Leukocyte alkaline phosphatase in pregnancy. Comparison with placental phosphatase activity.
Topics: Alkaline Phosphatase; Electrophoresis; Female; Glycerophosphates; Hot Temperature; Humans; Leukocytes; Nitrophenols; Phenylalanine; Placenta; Pregnancy; Protein Denaturation | 1970 |
[Fetal brain damage in maternal heterozygous phenylketonuria].
Topics: Adult; Brain Damage, Chronic; Female; Heterozygote; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1970 |
Unrecognized maternal biochemical disease: an uncommon cause of mental retardation in children.
Topics: Child; Cystinuria; Female; Glycine; Humans; Infant, Newborn; Intellectual Disability; Lysine; Metabolic Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Proline; Tyrosine | 1970 |
Serotonin synthesis inhibition and estrous behavior in female rats.
Topics: Animals; Brain Chemistry; Castration; Dopamine; Estradiol; Estrus; Female; Pargyline; Phenylalanine; Pregnancy; Progesterone; Rats; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal | 1970 |
Effects of maternal phenylketonuria on the rat fetus.
Topics: Animals; Birth Weight; Cataract; Embryonic and Fetal Development; Female; Fetal Death; Fetus; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats | 1970 |
A learning impairment associated with induced phenylketonuria.
Topics: Age Factors; Amino Acids; Animals; Behavior, Animal; Body Weight; Chromatography, Thin Layer; Diet; Female; Humans; Learning Disabilities; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Pregnancy, Animal; Rats; Tyrosine | 1970 |
Milk production response to supplementation with encapsulated methionine per Os or casein per abomasum.
Topics: Abomasum; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Caseins; Cattle; Female; Glycine; Isoleucine; Kaolin; Lactation; Leucine; Methionine; Milk; Perfusion; Phenylalanine; Pregnancy; Triglycerides; Valine | 1970 |
[Hyperphenylalaninemia].
Topics: Adult; Female; Humans; Infant, Newborn; Metabolism, Inborn Errors; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy | 1971 |
Phenylalanine transport in utero.
Topics: Amniotic Fluid; Autoradiography; Biological Transport, Active; Erythrocytes; Female; Fetus; Heart Rate; Humans; Kidney Tubules; Liver; Macrophages; Maternal-Fetal Exchange; Perfusion; Phenylalanine; Pregnancy; Trophoblasts; Tyrosine; Uterus | 1971 |
Placental transfer of amino acids in the rat. II. Aromatic amino acids.
Topics: Animals; Biological Transport, Active; Female; Fetus; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Rats; Time Factors; Tryptophan; Tyrosine | 1971 |
Circular dichroism studies on human chorionic somatomammotropin.
Topics: Acetates; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Circular Dichroism; Female; Glycine; Guanidines; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Molecular Weight; Osmotic Pressure; Phenylalanine; Placental Hormones; Placental Lactogen; Pregnancy; Protein Denaturation; Sodium Hydroxide; Tromethamine; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Essential amino acids for milk protein synthesis in the in vitro secretory cell and stimulation by elevated levels.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Caseins; Cattle; Culture Techniques; Cystine; Female; Glutamine; Histidine; Isoleucine; Lactation; Lactoglobulins; Leucine; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Pregnancy; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Inherited high alkaline phosphatase activity in cattle serum.
Topics: Alkaline Phosphatase; Animals; Cattle; Female; Genes, Dominant; Male; Phenylalanine; Pregnancy; Twins | 1967 |
Automated differential isoenzyme analysis. I. L-phenylalanine-sensitive isoenzymes of human serum alkaline phosphatase.
Topics: Alkaline Phosphatase; Autoanalysis; Bone Diseases; Female; Humans; Indicators and Reagents; Intestinal Absorption; Intestines; Isoenzymes; Liver Diseases; Methods; Neoplasms; Phenylalanine; Placenta; Pregnancy; Spectrophotometry | 1967 |
Biochemical and behavioral effects of a commercial "low phenylalanine" diet in growing rats.
Topics: Animals; Animals, Newborn; Avoidance Learning; Brain; Conditioning, Operant; Diet; Female; Glutamine; Growth; Ligases; Liver; Mixed Function Oxygenases; Phenylalanine; Pregnancy; Rats; Tyrosine | 1968 |
[An in vitro study of the synthesis of serum proteins in the human placenta].
Topics: Autoradiography; Blood Proteins; Carbon Isotopes; Female; Humans; Immunoelectrophoresis; Phenylalanine; Placenta; Pregnancy | 1968 |
[On the distribution and clinical characteristics of phenylpyruvic oligophrenia].
Topics: Adolescent; Adult; Brain Injuries; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy | 1968 |
Action of oestrogen on the blastocyst and uterus in delayed implantation--an autoradiographic study.
Topics: Animals; Autoradiography; DNA; Embryo Implantation; Embryo, Mammalian; Estrogens; Female; Nucleosides; Phenylalanine; Pregnancy; Protein Biosynthesis; Rats; RNA; Thymidine; Time Factors; Tritium; Uterus | 1968 |
Maternal phenylketonuria: implications for growth and development.
Topics: Abnormalities, Multiple; Adult; Birth Weight; Body Height; Body Weight; Child; Child Development; Child, Preschool; Embryonic and Fetal Development; Female; Gestational Age; Growth; Heterozygote; Humans; Infant; Intellectual Disability; Intelligence Tests; Male; Microcephaly; Middle Aged; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1968 |
The effect on lactation of feeding large quanities of single amino acids.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Female; Glycine; Growth; Lactation; Leucine; Lysine; Methionine; Phenylalanine; Pregnancy; Rats | 1968 |
Conversion of phenylalanine to tyrosine in the bovine mammary secretory cell.
Topics: Animals; Carbon Isotopes; Caseins; Cattle; Female; Kidney; Lactation; Lactoglobulins; Liver; Mammary Glands, Animal; Mixed Function Oxygenases; Muscles; Myocardium; Phenylalanine; Pregnancy; Rats; Tyrosine | 1968 |
[Some peculiarities of transfer RNA of lactiferous gland tissue in various functional states].
Topics: Age Factors; Animals; Cattle; Female; Glutamates; Lactation; Lysine; Mammary Glands, Animal; Methionine; Nucleotides; Phenylalanine; Pregnancy; Protein Biosynthesis; Ribonucleases; RNA, Transfer | 1968 |
[Ribosomes of the mammary gland. Isolation and the capacity to incorporate in vitro amino acids into proteins].
Topics: Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Female; Lactation; Leucine; Liver; Mammary Glands, Animal; Phenylalanine; Pregnancy; Proline; Protein Biosynthesis; Rabbits; Ribosomes; Spectrum Analysis | 1968 |
[Excretion of phenylacetylglutamine in the newborn with birth trauma, intrauterine hypotrophy and hemolytic disease].
Topics: Birth Injuries; Congenital Abnormalities; Erythroblastosis, Fetal; Female; Fetal Diseases; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Pregnancy | 1968 |
The effects of p-chlorophenylalanine and phenylalanine on brain ester-bound fatty acids of developing rats.
Topics: Animals; Brain; Brain Chemistry; Esters; Fatty Acids; Female; Humans; Oleic Acids; Phenylalanine; Phenylketonurias; Pregnancy | 1968 |
[Immunological and biochemical indices of the blood serum in pregnancy with nephropathy].
Topics: Adult; Antistreptolysin; Blood Proteins; C-Reactive Protein; Female; Humans; Kidney Diseases; Phenylalanine; Pregnancy; Pregnancy Complications; Serologic Tests | 1968 |
Umbilical vein-artery and uterine arterio-venous plasma amino acid differences (in the human subject).
Topics: Amino Acids; Analysis of Variance; Cesarean Section; Delivery, Obstetric; Female; Fetus; Gestational Age; Histidine; Humans; Infant, Newborn; Infant, Premature; Leucine; Lysine; Maternal-Fetal Exchange; Nitrogen; Phenylalanine; Placenta; Pregnancy; Serine; Tyrosine; Umbilical Arteries; Umbilical Veins; Uterus | 1969 |
Characterization of placental isoenzyme of alkaline phosphatase in human pregnancy serum.
Topics: Aging; Alkaline Phosphatase; Blood Protein Electrophoresis; Delivery, Obstetric; Female; Hot Temperature; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Isoenzymes; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Umbilical Cord; Vibrio | 1969 |
Time sequence of action of estrogen on nucleic acid and protein synthesis in the uterus and blastocyst during delayed implantation in the rat.
Topics: Animals; Autoradiography; Castration; DNA; Embryo Implantation; Estradiol; Estrogens; Female; Nucleosides; Ovary; Ovum; Phenylalanine; Pregnancy; Pregnancy, Animal; Progesterone; Protein Biosynthesis; Rats; RNA; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Uterus | 1969 |
Effects on rat offspring of maternal phenylalanine diet during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Female; Phenylalanine; Pregnancy; Pregnancy, Animal; Rats | 1965 |
Dopamine and basal ganglia disorders.
Topics: Adult; Basal Ganglia; Dopamine; Female; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic Acid; In Vitro Techniques; Infant, Newborn; Male; Malignant Carcinoid Syndrome; Middle Aged; Movement Disorders; Parkinson Disease; Phenylalanine; Pregnancy; Serotonin; Tryptophan; Urine | 1965 |
Maternal phenylketonuria.
Topics: Adult; Child; Diet; Female; Humans; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications | 1966 |
Prenatal and postnatal developmental consequences of maternal phenylketonuria.
Topics: Adult; Birth Weight; Congenital Abnormalities; Female; Fetal Diseases; Humans; Infant, Newborn; Intellectual Disability; Male; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1966 |
Development of structure and function in the mammalian yolk sac. 3. The development of amino acid transport by rabbit yolk sac.
Topics: Alanine; Amino Acids; Animals; Betaine; Biological Transport; Carbon Isotopes; Female; Fetus; Glycine; Glycosides; In Vitro Techniques; Inulin; Isoleucine; Lysine; Maternal-Fetal Exchange; Methionine; Phenylalanine; Placenta; Pregnancy; Pregnancy, Animal; Proline; Quaternary Ammonium Compounds; Rabbits; Valine | 1966 |