phenylalanine and Parkinson Disease

phenylalanine has been researched along with Parkinson Disease in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (63.33)	18.7374
1990's	3 (10.00)	18.2507
2000's	1 (3.33)	29.6817
2010's	5 (16.67)	24.3611
2020's	2 (6.67)	2.80

Authors

Authors	Studies
Dai, L; Du, Z; Fang, Y; Jiang, H; Li, F; Li, H; Liu, C; Liu, Z; Meng, L; Tian, Y; Wang, Z; Xiong, M; Yan, Z; Yu, T; Yuan, X; Zhang, J; Zhang, Z	1
Amara, AW; Comella, C; Emsellem, H; Gottwald, MD; Hauser, RA; Jochelson, P; Liu, K; Schweitzer, PK; Steinerman, JR; Sterkel, AL; Videnovic, A; Zomorodi, K	1
Artis, DR; Baker, J; Bova, M; Brecht, E; Callaway, K; Chiou, S; Diep, L; Johnston, JA; Lougheed, JC; Nguyen, L; Regnstrom, K; Riley, BE; Shaler, T; Velasquez, M; Walker, D; Yang, Y; Yao, N; Yednock, T; Zhang, Z	1
Soloway, AH; Soloway, PD; Warner, VD	1
Cai, Z; Chen, LL; Chua, KK; Li, M; Liu, LF; Luan, H; Meng, N; Mok, VC; Song, JX; Tang, Z; Xie, LX	1
Hirayama, M; Ohno, K; Tsuda, T; Tsunoda, M; Yamamoto, M	1
Deng, W; Liu, J; Qin, C; Wang, H; Xu, Y; Zhang, L; Zhu, H	1
Becker, G; Gerlach, M; Lange, KW; Mecklinger, L; Naumann, M; Tucha, O; Walitza, S	1
Breakefield, XO; Ozelius, LJ	1
Beckner, RM; Cedarbaum, JM; Gauger, LL; Hauser, RA; Nutt, JG; Olanow, CW; Woodward, WR	1
Daniel, PM; Moorhouse, RS; Pratt, OE	1
Fischer, E; Heller, B; Martin, R	1
Fischer, E	1
Gancher, ST; Irwin, RP; Nutt, JG; Woodward, WR	1
Birkmayer, W	1
Birkmayer, W; Mentasti, M	1
Vogt, M	1
Granerus, AK; Jagenburg, R; Rödjer, S; Svanborg, A	3
Dinsmore, SR; Mrochek, JE; Ohrt, DW	1
Aronson, RB; Cotzias, GC; Gellene, R; Papavasiliou, PS	1
Cotzias, GC; Düby, S; Ginos, J; Papavasiliou, PS; Steck, A	1
Fellman, JH; Joyce, JR; Strandholm, JJ	1
Cotzias, GC; Schiffer, LM; Van Woert, MH	1
Tubaro, E	1
Jagenburg, R	1
Braham, J; Crispin, M; Golan, R; Levin, N; Sarova-Pinhas, I; Szeinberg, A	1
Cooksey, B; Loncin, M; O'Reilly, S	1

Reviews

2 review(s) available for phenylalanine and Parkinson Disease

Article	Year
Release from brain tissue of compounds with possible transmitter function: interaction of drugs with these substances. British journal of pharmacology, 1969, Volume: 37, Issue:2 Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Chlorpromazine; Dopamine; Humans; Norepinephrine; Parkinson Disease; Phenothiazines; Phenylacetates; Phenylalanine; Serotonin; Synaptic Transmission	1969
Metabolic modification of Parkinson's disease and of chronic manganese poisoning. Annual review of medicine, 1971, Volume: 22 Topics: Animals; Brain; Choline; Chronic Disease; Dihydroxyphenylalanine; Drug Synergism; Humans; Manganese Poisoning; Melatonin; Methionine; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenylalanine; Poisoning; Pyridoxine; Tryptophan; Tyrosine	1971

Trials

5 trial(s) available for phenylalanine and Parkinson Disease

Article	Year
Solriamfetol for Excessive Daytime Sleepiness in Parkinson's Disease: Phase 2 Proof-of-Concept Trial. Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:10 Topics: Adult; Carbamates; Disorders of Excessive Somnolence; Double-Blind Method; Humans; Parkinson Disease; Phenylalanine	2021
Brain dopamine and kinematics of graphomotor functions. Human movement science, 2006, Volume: 25, Issue:4-5 Topics: Adult; Aged; Antiparkinson Agents; Biomechanical Phenomena; Brain; Computer Graphics; Cross-Over Studies; Dopamine; Dopamine Agonists; Double-Blind Method; Echoencephalography; Female; Handwriting; Humans; Male; Middle Aged; Parkinson Disease; Phenylalanine; Reaction Time; Reference Values; Signal Processing, Computer-Assisted; Substantia Nigra; Synaptic Transmission; Tyrosine	2006
Pharmacodynamics of the hypotensive effect of levodopa in parkinsonian patients. Clinical neuropharmacology, 1992, Volume: 15, Issue:5 Topics: Amino Acids; Blood Pressure; Brain; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypotension; Infusions, Intravenous; Levodopa; Locomotion; Male; Middle Aged; Motor Activity; Parkinson Disease; Phenylalanine	1992
Parkinsonism and DOPA. Transactions of the Association of American Physicians, 1968, Volume: 81 Topics: 5-Hydroxytryptophan; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Humans; Male; Manganese Poisoning; Mining; Occupational Diseases; Parkinson Disease; Phenylacetates; Phenylalanine; Placebos	1968
Aromatic amino acids and modification of parkinsonism. The New England journal of medicine, 1967, Feb-16, Volume: 276, Issue:7 Topics: Adult; Aged; Agranulocytosis; Bone Marrow Examination; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Humans; Male; Manganese; Melanocyte-Stimulating Hormones; Middle Aged; Parkinson Disease; Phenylalanine; Placebos	1967

Other Studies

23 other study(ies) available for phenylalanine and Parkinson Disease

Article	Year
Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis. Chemosphere, 2022, Volume: 308, Issue:Pt 2 Topics: alpha-Synuclein; Animals; Environmental Pollutants; Fungicides, Industrial; Humans; Maneb; Metabolomics; Mice; Neuroblastoma; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Phenylalanine; Proteomics; Tryptophan	2022
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nature communications, 2013, Volume: 4 Topics: Biocatalysis; Catalytic Domain; Humans; Mitochondria; Models, Molecular; Mutation; Parkinson Disease; Phenylalanine; Protein Structure, Tertiary; Ubiquitin-Protein Ligases	2013
Possible chemical initiators of cognitive dysfunction in phenylketonuria, Parkinson's disease and Alzheimer's disease. Medical hypotheses, 2013, Volume: 81, Issue:4 Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methionine; Models, Biological; Molecular Structure; Oxidative Stress; Parkinson Disease; Phenylalanine; Phenylketonurias; Tyrosine	2013
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease. Journal of proteome research, 2015, Jan-02, Volume: 14, Issue:1 Topics: alpha-Synuclein; Animals; Biomarkers; Chromatography, Liquid; Drosophila melanogaster; Fatty Acids; Histidine; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Nucleotides; Parkinson Disease; Phenotype; Phenylalanine; Steroids; Tryptophan; Tyrosine	2015
Serum Tyrosine-to-Phenylalanine Ratio is Low in Parkinson's Disease. Journal of Parkinson's disease, 2016, 04-02, Volume: 6, Issue:2 Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Parkinson Disease; Phenylalanine; Sweat; Tyrosine	2016
S100B transgenic mice develop features of Parkinson's disease. Archives of medical research, 2011, Volume: 42, Issue:1 Topics: Animals; Brain; Dopamine; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 5; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Growth Factors; Parkinson Disease; Phenylalanine; Platelet-Derived Growth Factor; Psychomotor Performance; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotarod Performance Test; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Serotonin	2011
Dopa and parkinsonism. British medical journal, 1967, Jun-24, Volume: 2, Issue:5555 Topics: Dihydroxyphenylalanine; Humans; Parkinson Disease; Phenylalanine	1967
Co-factor insufficiency in dystonia-parkinsonian syndrome. Nature genetics, 1994, Volume: 8, Issue:3 Topics: Age of Onset; Biopterins; Chromosome Mapping; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 9; Dopamine; Dystonia; Genes, Dominant; Genes, Recessive; GTP Cyclohydrolase; Humans; Japan; Jews; Parkinson Disease; Phenylalanine; Syndrome; Tyrosine 3-Monooxygenase; X Chromosome	1994
The effect of L-dopa infusions with and without phenylalanine challenges in parkinsonian patients: plasma and ventricular CSF L-dopa levels and clinical responses. Neurology, 1993, Volume: 43, Issue:9 Topics: Amino Acids; Biological Transport; Blood-Brain Barrier; Humans; Infusions, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylalanine	1993
Letter: Do changes in blood levels of other aromatic aminoacids influence levodopa therapy? Lancet (London, England), 1976, Jan-10, Volume: 1, Issue:7950 Topics: Amino Acids; Blood-Brain Barrier; Histidine; Humans; Levodopa; Parkinson Disease; Phenylalanine; Tryptophan	1976
Therapeutic action of D-phenylalanine in Parkinson's disease. Arzneimittel-Forschung, 1976, Volume: 26, Issue:4 Topics: Depression; Humans; Parkinson Disease; Phenylalanine	1976
The phenethylamine hypothesis of thymic homeostasis. Biological psychiatry, 1975, Volume: 10, Issue:6 Topics: Antidepressive Agents; Brain; Depression; Homeostasis; Humans; Isomerism; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenethylamines; Phenylalanine; Thymus Gland	1975
[Experimental findings and new aspects in extrapyramidal diseases]. Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1966, Volume: 23, Issue:1 Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Monoamine Oxidase Inhibitors; Movement Disorders; Norepinephrine; Parkinson Disease; Perphenazine; Phenylalanine; Reserpine; Serotonin; Tyrosine	1966
[Further experimental studies on the catecholamine metabolism in extrapyramidal diseases (Parkinson and chorea syndromes)]. Archiv fur Psychiatrie und Nervenkrankheiten, 1967, Aug-08, Volume: 210, Issue:1 Topics: Aged; Carboxy-Lyases; Catecholamines; Chorea; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Middle Aged; NAD; Oxidoreductases; Parkinson Disease; Phenylalanine; Tyrosine	1967
Variations in L-dopa absorption. Report of a parkinsonian patient with high plasma dopa concentration after therapeutical L-dopa dose. Acta medica Scandinavica, 1974, Volume: 196, Issue:6 Topics: Administration, Oral; Aged; Carbon Radioisotopes; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Female; Humans; Injections, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylalanine; Stimulation, Chemical; Sulfates; Tyrosine	1974
Monitoring phenylalanine-tyrosine metabolism by high-resolution liquid chromatography of urine. Clinical chemistry, 1973, Volume: 19, Issue:8 Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autistic Disorder; Carbidopa; Catechols; Child; Chromatography, Gas; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Hippurates; Homovanillic Acid; Humans; Hyperkinesis; Intellectual Disability; Lactates; Mandelic Acids; Mass Spectrometry; Methods; Nervous System Diseases; Parkinson Disease; Phenylacetates; Phenylalanine; Spectrophotometry, Ultraviolet; Tyrosine	1973
Analysis in human plasma of 3-methoxytyrosine: a metabolite of DOPA. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 32, Issue:2 Topics: Chromatography, Ion Exchange; Dihydroxyphenylalanine; Ethers; Fasting; Humans; Mass Spectrometry; Parkinson Disease; Phenylalanine; Tyrosine	1971
Phenylalanine absorption and metabolism in Parkinsonian patients. British medical journal, 1971, Oct-30, Volume: 4, Issue:5782 Topics: Administration, Oral; Aged; Female; Half-Life; Humans; Injections, Intravenous; Intestinal Absorption; Male; Middle Aged; Parkinson Disease; Phenylalanine; Tyrosine	1971
[Advancement on the area of antiparkinsonism drugs]. Bollettino chimico farmaceutico, 1969, Volume: 108, Issue:8 Topics: Amantadine; Amino Acids; Brain; Dihydroxyphenylalanine; Humans; Parkinson Disease; Phenylalanine	1969
[Parkinson's syndrome. 11. Intestinal resorption]. Lakartidningen, 1970, Oct-14, Volume: 67, Issue:42 Topics: Administration, Oral; Dihydroxyphenylalanine; Humans; Injections, Intravenous; Intestinal Absorption; Parkinson Disease; Phenylalanine	1970
Inhibition of L-Phenylalanine absorption by L-DOPA in patients with parkinsonism. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:3 Topics: Aged; Dihydroxyphenylalanine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Parkinson Disease; Phenylalanine; Time Factors	1971
Oral phenylalanine and tyrosine tolerance tests in Parkinsonian patients. British medical journal, 1969, May-31, Volume: 2, Issue:5656 Topics: Adult; Aged; Female; Humans; Intestinal Absorption; Male; Middle Aged; Parkinson Disease; Phenylalanine; Statistics as Topic; Tyrosine; Xylose	1969
Dopamine and basal ganglia disorders. Neurology, 1965, Volume: 15, Issue:11 Topics: Adult; Basal Ganglia; Dopamine; Female; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic Acid; In Vitro Techniques; Infant, Newborn; Male; Malignant Carcinoid Syndrome; Middle Aged; Movement Disorders; Parkinson Disease; Phenylalanine; Pregnancy; Serotonin; Tryptophan; Urine	1965