phenylalanine and Neoplasms

phenylalanine has been researched along with Neoplasms in 164 studies

Research

Studies (164)

TimeframeStudies, this research(%)All Research%
pre-199086 (52.44)18.7374
1990's19 (11.59)18.2507
2000's20 (12.20)29.6817
2010's25 (15.24)24.3611
2020's14 (8.54)2.80

Authors

AuthorsStudies
Nishimori, I; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D1
Afzal, S; Channar, PA; Ejaz, SA; Erben, MF; Iqbal, J; Larik, FA; Lecka, J; Mahesar, PA; Saeed, A; Sévigny, J1
Chien, HC; Colas, C; Giacomini, KM; Hall, C; Schlessinger, A; Thomas, AA; Wells, A; Wolfe, H1
Lehmann, F; Lindberg, J; Nilvebrant, J; Nygren, PÅ1
Fukuda, H1
Agami, R; Altelaar, M; Bassani-Sternberg, M; Bleijerveld, OB; Blommaert, N; Champagne, J; de Gooijer, MC; Georgiou, G; Joosten, RP; Kenski, J; Laos, M; Lovecchio, D; Michaux, J; Mordente, K; Nagel, R; Navarro, JM; Nielsen, MM; Olweus, J; Pak, HS; Pataskar, A; Peeper, DS; Perrakis, A; Stone, E; van Tellingen, O1
Ahmad, SM; Bhagat, M; Faheem, MM; Goswami, A; Kaur, G; Mir, KB; Rahim, JU; Rai, R1
Marnani, MB; Oftadeh, M; Sohrabi, N1
Chmiela, M; Gonciarz, W; Pająk, M; Sutradhar, M; Woźniczka, M1
Hirano, F; Kondo, N; Murata, Y; Sudani, A; Temma, T1
Chen, H; Duan, K; Guo, J; Li, R; Wan, H; Xu, Y; Yuan, Z; Zhang, J; Zheng, J1
Inoue, Y; Kanamori, K; Matsui, M; Nishiyama, N; Nomoto, T; Suzuki, M; Takemoto, H; Tomoda, K; Yao, Y1
Aoki, M; Harada, T; Hirose, K; Ichise, K; Kato, T; Sato, M; Takai, Y; Takeda, K; Wada, Y1
Fukunaga, H; Matsuya, Y; Omura, M; Tokuuye, K1
Fukuda, H; Hiratsuka, J1
Jevremovic, T; Moffitt, G; Stewart, RD; Streitmatter, SW1
Birault, A; Chinnathambi, S; Doan, TL; Komatsu, A; Laird, M; Mai, NXD; Matsumoto, K; Morrison, K; Raitano, A; Suzuki, M; Takata, T; Tamanoi, F1
Ding, Q; Han, X; Li, S; Liu, Z; Qi, H; Qiao, X; Song, Y; Zhong, Y; Zhou, G1
Choi, JS; Lee, S; Ryu, KS; Song, SJ1
Aubatin, A; Castellano, F; Decrouy, X; Donnadieu, E; Molinier-Frenkel, V; Sako, N1
Castellano, F; Molinier-Frenkel, V1
Cortez-Maya, S; Hernández-Ortega, S; Martínez-García, M; Martínez-Klimov, ME; Martínez-Klimova, E; Pedro-Hernández, LD; Ramírez-Ápan, T; Vargas-Medina, AC1
Buuh, ZY; Cai, W; Du, J; Jiang, D; Kang, L; Lyu, Z; McGuth, JC; Wang, RE; Wissler, HL1
Brustad, EM; Chilkoti, A; Costa, SA; Dzuricky, MJ; Isaacs, FJ; Mozhdehi, D1
Arano, Y; Hanaoka, H; Higuchi, T; Ishioka, NS; Ohshima, Y; Suzuki, H; Tsushima, Y; Yamaguchi, A1
Gao, YF; Liu, J; Qi, YM; Shi, RR; Zhai, MX; Zhai, WJ; Zou, Z1
Goto, K; Hamura, K; Kwon, O; Lee, C; Lu, J; Tamanoi, F; Yoshimura, K1
Alvfors, C; Berglund, Å; Gullbo, J; Hagberg, H; Harmenberg, J; Jerling, M; Lewensohn, R; Lisyanskaya, A; Nordström, E; Nygren, P; Orlov, S; Ringbom, M; Söderlind, K; Spira, J; Tholander, B; Ullén, A1
Yoshimoto, M1
Li, W; Liu, Q; Liu, Y; Ma, E; Sheng, L; Shi, J; Sun, H; Yuan, L; Zhang, C; Zou, C1
Xiao, YX; Yang, WX1
Ali, MR; El-Sayed, MA; Fernández, FM; Han, T; Tang, Y; Wu, R; Wu, Y; Xiao, H; Zang, X1
Nakamura, H1
Albritton, JR; Auterinen, I; Binns, PJ; Harling, OK; Kiger, WS; Marek, M; Moss, RL; Nievaart, VA; Rezaei, A; Riley, KJ; Savolainen, S; Seppälä, T; Sköld, K; Viererbl, L1
Ageno, W; Appio, L; Brivio, L; Campiotti, L; Crowther, M; Dentali, F; Grandi, AM; Squizzato, A1
Collette, L; Moss, R; Sauerwein, WA; Wittig, A1
Altieri, S; Cionini, L; Menichetti, L; Minn, H; Salvadori, PA; Sauerwein, WA; Solin, O1
Arnopolskaya, AM; Khokhlov, VF; Kozlovskaya, NG; Kulakov, VN; Mitin, VN; Portnov, AA; Sheino, IN; Zaitsev, KN1
Aburai, K; Kawatobi, S; Matsumura, A; Nakai, K; Okuno, H; Shirakawa, M; Tsurubuchi, T; Yamamoto, Y; Yamamto, T; Yokoyama, Y1
Fang, H; Li, M; Li, Q; Wang, X; Xu, W; Yuan, Y; Zhang, L; Zhang, X; Zhu, H1
Fang, Q; Feng, C; Gu, G; Hou, J; Li, Z; Liu, P; Shen, J; Shi, Y; Wang, H; Wang, P; Xu, F; Yin, Z1
Cho, SH; Duin, EC; Hong, JW; Jambovane, S; Kim, SK; Yun, JY1
Guan, W; Hu, Z; Huang, Y; Sun, S; Yao, Y; Zhang, C1
Barsoum, J; Borella, C; Foley, KP; Jiang, J; Korbut, T; Li, H; Sang, J; Sonderfan, AJ; Wu, Y; Ye, J; Zhang, M; Zhang, X; Zhou, D1
Fujiwara, K; Kinashi, Y; Kurihara, K; Ono, K; Sakurai, Y; Takahashi, S; Takahashi, T; Tanaka, H; Yashima, H1
Alam, S; Chauhan, VS; Kaul, A; Kumar, S; Kundu, GC; Mishra, AK; Panda, JJ1
Augustin, HG1
KHOKHLOV, AS; LARIONOV, LF; NOVIKOVA, MA; SHKODINSKAJA, EN; TROOSHEIKINA, VI; VASINA, OS1
BALTUS, E; LEDOUX, L; VANDERHAEGHE, F1
DI PIETRO, S1
CHEBOTAREVA, LI1
SELIGER, H1
GIGANTE, D1
ESTEVEZ, RA; TRIMBOLI DE ESTEVEZ, O1
ECKHARDT, A; SELLEI, C1
TRUSHEIKINA, VI2
CREECH, O; KREMENTZ, ET; RYAN, RF1
BAKER, BR; BREENBERG, J; GREENE, MO1
P'AN, CT1
CASTELLANO, M; CATTANEO, C1
DAVYDOVA, SIa; SAPOZHNIKOVA, MB1
DIDDLE, AW; JENKINS, HH; WATTS, G; WATTS, J1
SMIRNOVA, EV1
CHIRIGOS, MA; FANNING, GR; GUROFF, G1
PAN, TT1
CHEN, JT; HSU, B; KAO, YS; PAN, PC1
CHEN, JT; HSU, B; JEN, YF; KAO, YS; WU, TC1
SULLIVAN, MP; SUTOW, WW; TAYLOR, G1
NIELSEN, G1
CHANG, HY; CHI, HC; FAN, LL; HAN, J; HO, S; LEI, HP; LI, KT; LIU, KT; WANG, CK1
GENTY, N; MELONI, GA; VENDRELY, R1
CHO, YS; MORRIS, HP; PITOT, HC1
BELLELLI, L; BONACCISEZZI, ML1
DOGLIOTTI, GC1
CHRISTENSEN, HN1
CHANG, CN; CHEN, PZ; CHOW, HL; YIH, YF; YUEN, CY1
AMOS, H; ASKONAS, B; SOEIRO, R1
LORINCZ, AB; RYAN, WL1
KHROMOV, BM; KIREEVA, OV1
CLARK, RL; SMITH, JL; STEHLIN, JS1
BAKER, BR; GOODMAN, L; LEE, WW; MARTINEZ, AP; SCHELSTRAETE, MG; TONG, GL; WEINSTEIN, B1
LEVINE, RJ; LOVENBERG, W; SJOERDSMA, A1
ALLAN, JD; IRELAND, JT; MILNER, J; MOSS, AD1
KLATT, O; MILNER, AN; STEHLIN, JS; YOUNG, SE1
BADEN, HP; PEARLMAN, C1
FOX, WW; HAWKINS, RA; SCANLON, EF; SMITH, WS1
BUTEL, JS; FELDMAN, LA; KITAHARA, T; MELNICK, JL; RAPP, F1
DAO, TL; GRINBERG, R; NEMOTO, T1
KHOKHLOV, AS; LARIONOV, LF; NOVIKOVA, MA; SKHODINSKAIA, EN; TRUSHEIKINA, VL; VASINA, OS1
LARIONOV, LF; PEREVODCHIKOVA, NI1
PUKHAL'SKAIA, ECh1
HRUBAN, Z; SLESERS, A; WISSLER, RW1
RILEY, V1
Didziapetriene, J; Kadziauskas, J; Stanciūte, D1
Asano, T; Hattori, Y; Kirihata, M; Kondoh, H; Niki, Y; Wakamiya, T; Yamaguchi, Y1
Arakawa, H; Futamura, M; Kamino, H; Nakamura, Y; Yoshida, K1
Cornelissen, B; de Spiegeleer, B; Kersemans, K; Kersemans, V; Mertens, J; Slegers, G; Staelens, L1
Deisenroth, C; Jin, A; Lindström, MS; White Wolf, G; Zhang, Y1
Bidart, JM; Boige, V; Delaloge, S; Le Couedic, JP; Motté, N; Pautier, P; Saulnier, P; Soria, JC; Vainchenker, W; Villeval, JL1
Herz, F; Leahy, EM; Singer, RM1
Lin, JK; Wang, CH1
Dhondt, JL; Farriaux, JP1
Fishman, WH; Millán, JL; Ruoslahti, E; Stigbrand, T1
Barre, M; Bernard, L; Deumier, R; Donzelle, G; Lacome, M; Lanier, M; Mourtada, MB1
Judd, KP; Reif, AE; Southwick, PL1
Brown, PD1
Allen, BJ1
Chauvel, P; Pignol, JP1
Blumenkopf, TA; Cory, M; Elwell, L; Laethem, RM; Moxham, CP; Ray, PH; Smith, GK; Walton, LM1
Barter, J; Cole, A; Dickson, R; Hawkins, MJ; Low, J; Marshall, J; McCann, P; Moore, J; Ness, E; Sale, M; Wojtowicz-Praga, S1
Bartlett, K; Brock, C; Craft, AW; Daley, SE; Halliday, D; Hetherington, C; Kernahan, J; Pearson, AD; Price, L; Wyllie, RA1
Kuwano, M; Ono, M2
Brown, PD; Talbot, DC1
Carlsson, J; Gedda, L; Ghaneolhosseini, H; Hartman, T; Malmquist, J; Naeslund, C; Olsson, P; Sjöberg, S; Tjarks, W1
Dickson, RB; Hawkins, MJ; Wojtowicz-Praga, SM1
Imashuku, S1
Denis, LJ; Verweij, J1
Beattie, GJ; Smyth, JF1
Baramova, E; Foidart, JM; Frankenne, F; Maquoi, E; Munaut, C; Murphy, G; Noël, A; Remacle, A; Sounni, NE1
Broxterman, HJ; Gebbink, MF; Hoekman, K; Jorna, AS; Pinedo, HM; Verheul, HM1
Eckhardt, SG; Hidalgo, M1
Itoh, T; Itohara, S; Lannoy, K; Libert, C; Shapiro, SD; Vandekerckhove, J; Wielockx, B1
Kinashi, Y; Kobayashi, T; Masunaga, S; Ono, K; Sakurai, Y; Suzuki, M; Takagaki, M1
Kolár, J; Stĕpán, J; Volek, V1
Kubíková-Kourilová, A1
Matsumoto, M1
Wheatley, DN1
Ren, YF; Zheng, YY1
Kokolis, N; Ziegler, I1
Blokhin, NN1
Kitamura, M; Nakayama, T1
Arima, T; Fujii, S; Niinobe, M; Okuda, H; Tamura, Y1
Brennan, MF; Burt, ME; Gonenne, A; Heslin, MJ; Newman, E; Pearlstone, DB; Wolf, RF1
Bennett, BD; Gay, I; Morrison, GH; Zha, X1
Matsumoto, H; Mori, S1
Barth, RF; Fairchild, RG; Soloway, AH1
Duch, DS; Nichol, CA; Smith, GK1
Carter, JC; Jozwiak, EL; Mallinger, AG1
Folkers, K1
Presant, CA; Serpick, AA; Wiernik, PH1
Bodansky, O; Fleisher, M; Schwartz, MK1
Gingold, N; Pittermann, E; Stacher, A1
Galt, RM; Knock, FE; Oester, YT; Sylvester, R1
Stiller, KJ1
Hricko, AM1
Burdette, WJ1
Craddock, VM1
Demetriou, J; Nadler, S; Pileggi, VJ; Winkelman, J1
Hahn, K; Jesdinsky, HJ; Ladner, HA1
Kellen, JA; Lustig, V1
Hultin, T1
Stolbach, LL1
Glick, D; Hosoda, S1
Timperley, WR; Warnes, TW1
Fishman, WH; Green, S1
Bodnaryk, RP1
Montenero, P; Monti, A1
Kao, YS; Lee, T; Pan, PC; Yao, HY1
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1

Reviews

25 review(s) available for phenylalanine and Neoplasms

ArticleYear
Progress and Future Directions with Peptide-Drug Conjugates for Targeted Cancer Therapy.
    Molecules (Basel, Switzerland), 2021, Oct-05, Volume: 26, Issue:19

    Topics: Antineoplastic Agents; Cytotoxins; Drug Carriers; Drug Delivery Systems; Drug Design; Humans; Immunoconjugates; Melphalan; Neoplasms; Peptides; Pharmaceutical Preparations; Phenylalanine; Radiotherapy; Somatostatin

2021
Response of Normal Tissues to Boron Neutron Capture Therapy (BNCT) with
    Cells, 2021, 10-26, Volume: 10, Issue:11

    Topics: Animals; Borohydrides; Boron Neutron Capture Therapy; Humans; Neoplasms; Phenylalanine; Relative Biological Effectiveness; Sulfhydryl Compounds; Tissue Distribution

2021
Pharmacokinetics of
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 166

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography

2020
An Overview of l-Amino Acid Oxidase Functions from Bacteria to Mammals: Focus on the Immunoregulatory Phenylalanine Oxidase IL4I1.
    Molecules (Basel, Switzerland), 2017, Dec-05, Volume: 22, Issue:12

    Topics: Adaptive Immunity; Animals; B-Lymphocytes; Bacteria; Cell Differentiation; Cell Proliferation; Gene Expression Regulation; Germinal Center; Humans; L-Amino Acid Oxidase; Macrophages; Mice; Neoplasms; Oxidation-Reduction; Phenylalanine; T-Lymphocytes, Regulatory; Th17 Cells

2017
[Current Status and Prospects on PET Radiopharmaceuticals for Radiotherapy].
    Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2015, Volume: 35, Issue:1

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Coordination Complexes; Fluorine Radioisotopes; Humans; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles; Organometallic Compounds; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Thiosemicarbazones

2015
KIFC1: a promising chemotherapy target for cancer treatment?
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Alanine; Antineoplastic Agents; Centrosome; DNA; Female; Humans; Kinesins; Mitosis; Molecular Targeted Therapy; Neoplasms; Oocytes; ortho-Aminobenzoates; Phenanthrenes; Phenylalanine; Pregnancy; Protein Transport; Pyridines; Signal Transduction; Spermatogenesis

2016
[Boron delivery system for neutron capture therapy of cancer].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:5

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Drug Delivery Systems; Humans; Liposomes; Neoplasms; Phenylalanine; Positron-Emission Tomography

2008
JAK2V617F mutation for the early diagnosis of Ph- myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis.
    Blood, 2009, May-28, Volume: 113, Issue:22

    Topics: Algorithms; Amino Acid Substitution; Biomarkers, Tumor; Case-Control Studies; Early Detection of Cancer; Female; Gene Frequency; Humans; Janus Kinase 2; Male; Myeloproliferative Disorders; Neoplasms; Phenylalanine; Philadelphia Chromosome; Point Mutation; Valine; Venous Thromboembolism

2009
[Angiogenesis research--quo vadis?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2003, Volume: 100, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Bevacizumab; Cell Communication; Drug Evaluation, Preclinical; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ephrins; Forecasting; Growth Substances; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Lymphokines; Metalloendopeptidases; Mice; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Phenylalanine; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Research; Signal Transduction; Thalidomide; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
[REGIONAL PERFUSION IN CLINICAL PRACTICE; (REVIEW OF LITERATURE)].
    Klinicheskaia meditsina, 1963, Volume: 41

    Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Mechlorethamine; Neoplasms; Perfusion; Phenylalanine

1963
[Expression of matrix metalloproteinases in patients with malignant tumors].
    Medicina (Kaunas, Lithuania), 2004, Volume: 40, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Clinical Trials as Topic; Diphosphonates; Disease Progression; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasms; Organic Chemicals; Phenylalanine; Phenylbutyrates; Prognosis; Protease Inhibitors; Thiophenes; Time Factors; Tissue Inhibitor of Metalloproteinases

2004
[Tetrahydroblopterin. Metabolism and metabolic role of unconjugated pteridines (author's transl)].
    Pathologie-biologie, 1980, Volume: 28, Issue:6

    Topics: Animals; Biological Transport; Biopterins; Cattle; Humans; Mice; Mixed Function Oxygenases; Neoplasms; Neurotic Disorders; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Pteridines; Rats

1980
[Neutron capturing irradiation: principle, current results and perspectives].
    Bulletin du cancer. Radiotherapie : journal de la Societe francaise du cancer : organe de la societe francaise de radiotherapie oncologique, 1995, Volume: 82, Issue:3

    Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Cell Survival; Drug Carriers; Humans; Linear Energy Transfer; Neoplasms; Nuclear Reactors; Particle Accelerators; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Sulfhydryl Compounds

1995
[Development of anti tumor agents targeting angiogenesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Platelet Factor 4; Polysaccharides, Bacterial; Sesquiterpenes; Thalidomide; Thiophenes; Triazines; Triazoles; Tumor Cells, Cultured

1997
Experimental and clinical studies on the use of matrix metalloproteinase inhibitors for the treatment of cancer.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:14

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Ascites; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Extracellular Matrix; Female; Humans; Male; Metalloendopeptidases; Mice; Middle Aged; Neoplasms; Phenylalanine; Pleural Effusion, Malignant; Protease Inhibitors; Rats; Thiophenes

1996
Chemistry and biology of some low molecular weight boron compounds for boron neutron capture therapy.
    Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2

    Topics: Amino Acids; Boron Compounds; Boron Neutron Capture Therapy; DNA; Humans; Intercalating Agents; Molecular Structure; Neoplasms; Phenylalanine; Structure-Activity Relationship

1997
Matrix metalloproteinase inhibitors.
    Investigational new drugs, 1997, Volume: 15, Issue:1

    Topics: Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Down-Regulation; Drugs, Investigational; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Hydroxamic Acids; Metalloendopeptidases; Molecular Weight; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Phenylalanine; Protease Inhibitors; Protein Kinase C; Proteins; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tissue Inhibitor of Metalloproteinases

1997
Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment.
    International journal of hematology, 1997, Volume: 66, Issue:2

    Topics: Adult; Afibrinogenemia; Aged; Anticonvulsants; Autoimmune Diseases; Biomarkers; Child; Cytokines; Diagnosis, Differential; Ferritins; Histiocytosis, Non-Langerhans-Cell; Humans; Hypertriglyceridemia; Infections; Killer Cells, Natural; Lymphoma; Neoplasms; Phenylalanine

1997
Matrix metalloproteinase inhibitors: present achievements and future prospects.
    Investigational new drugs, 1997, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Enzyme Inhibitors; Extracellular Matrix; Humans; Hydroxamic Acids; Metalloendopeptidases; Neoplasm Metastasis; Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes

1997
[Neovascularization and tumor development].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, Aug-10, Volume: 87, Issue:8

    Topics: Angiostatins; Antibiotics, Antineoplastic; Antineoplastic Agents; Collagen; Cyclohexanes; Endostatins; Humans; Hydroxamic Acids; Interferons; Interleukin-12; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Peptide Fragments; Phenylalanine; Plasminogen; Sesquiterpenes; Thalidomide; Thiophenes

1998
Development of matrix metalloproteinase inhibitors in cancer therapy.
    Journal of the National Cancer Institute, 2001, Feb-07, Volume: 93, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biphenyl Compounds; Clinical Trials as Topic; Drugs, Investigational; Enzyme Inhibitors; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Neoplasms; Organic Chemicals; Phenylalanine; Phenylbutyrates; Protease Inhibitors; Pyrazines; Sulfonamides; Tetracycline; Tetracyclines; Thiophenes

2001
Biological and biochemical effects of phenylalanine analogs.
    International review of cytology, 1978, Volume: 55

    Topics: Aging; Animals; Cell Division; Enzyme Induction; Enzyme Repression; Flagella; Mutation; Neoplasms; Phenylalanine; Protein Biosynthesis; RNA; Transfer RNA Aminoacylation; Viruses

1978
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.
    Annual review of biochemistry, 1985, Volume: 54

    Topics: Alcohol Oxidoreductases; Animals; Biopterins; Body Fluids; Coenzymes; GTP Cyclohydrolase; Humans; Immune System Diseases; Mental Disorders; Metalloproteins; Molybdenum; Molybdenum Cofactors; Neoplasms; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Pterins; Tetrahydrofolate Dehydrogenase; Tissue Distribution; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1985
Current progress in the management of cancer. A collective review.
    Plastic and reconstructive surgery, 1969, Volume: 44, Issue:3

    Topics: Adenocarcinoma; Angiography; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Chemotherapy, Cancer, Regional Perfusion; DNA, Neoplasm; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Lymphography; Lymphoma, Non-Hodgkin; Male; Mammography; Melanoma; Mustard Compounds; Neoplasms; Phenylalanine; Radioisotopes; Radionuclide Imaging; Radiotherapy Dosage; Selenium; Skin Neoplasms; Thermography; Time Factors

1969
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015

Trials

5 trial(s) available for phenylalanine and Neoplasms

ArticleYear
First-in-human, phase I/IIa clinical study of the peptidase potentiated alkylator melflufen administered every three weeks to patients with advanced solid tumor malignancies.
    Investigational new drugs, 2015, Volume: 33, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alkylation; Antineoplastic Agents, Alkylating; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Male; Melphalan; Middle Aged; Neoplasms; Peptide Hydrolases; Phenylalanine; Prospective Studies

2015
Early clinical trial concept for boron neutron capture therapy: a critical assessment of the EORTC trial 11001.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Adenocarcinoma; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Colorectal Neoplasms; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Male; Neoplasms; Phenylalanine; Prospective Studies; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Thyroid Neoplasms; Tissue Distribution

2009
Phase I trial of a novel matrix metalloproteinase inhibitor batimastat (BB-94) in patients with advanced cancer.
    Investigational new drugs, 1996, Volume: 14, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Collagenases; Drug Administration Schedule; Female; Gelatinases; Humans; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Middle Aged; Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes

1996
Phase I study of intraperitoneal metalloproteinase inhibitor BB94 in patients with malignant ascites.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Ascites; Dose-Response Relationship, Drug; Female; Humans; Male; Metalloendopeptidases; Middle Aged; Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes

1998
Growth hormone and insulin reverse net whole body and skeletal muscle protein catabolism in cancer patients.
    Annals of surgery, 1992, Volume: 216, Issue:3

    Topics: Amino Acids; Blood Glucose; Creatinine; Female; Growth Hormone; Hematocrit; Humans; Insulin; Leucine; Male; Middle Aged; Muscle Proteins; Neoplasms; Phenylalanine; Recombinant Proteins

1992

Other Studies

134 other study(ies) available for phenylalanine and Neoplasms

ArticleYear
Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Amines; Amino Acids; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Conserved Sequence; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Structure; Neoplasms; Sequence Alignment; Structure-Activity Relationship

2008
Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Alkaline Phosphatase; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazoles; Pyrophosphatases; Structure-Activity Relationship

2018
l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Antineoplastic Agents; Brain Diseases; Click Chemistry; Dose-Response Relationship, Drug; Histidine; Humans; Large Neutral Amino Acid-Transporter 1; Molecular Structure; Neoplasms; Prodrugs; Structure-Activity Relationship; Triazoles; Tryptophan

2019
Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
    Nature, 2022, Volume: 603, Issue:7902

    Topics: Codon; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Neoplasms; Phenylalanine; T-Lymphocytes; Tryptophan; Tryptophan Oxygenase; Tryptophan-tRNA Ligase

2022
Heterochiral dipeptide d-phenylalanyl- l-phenylalanine (H-
    Molecular carcinogenesis, 2022, Volume: 61, Issue:12

    Topics: Animals; Cell Line; Cell Line, Tumor; Dipeptides; Mice; Neoplasms; Phenylalanine; Tumor Suppressor Protein p53

2022
Adsorption of folic acid molecule on diphenylalanine peptide nanohole as a drug delivery in cancer treatment: a molecular dynamics simulation study.
    Journal of molecular modeling, 2023, Jun-16, Volume: 29, Issue:7

    Topics: Adsorption; Folic Acid; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Neoplasms; Peptides; Phenylalanine; Water

2023
Equilibria in the aqueous system of cobalt(II) based on 2-picolinehydroxamic acid and N-(2-hydroxybenzyl)phenylalanine and its ability to inhibit the propagation of cancer cells.
    Journal of inorganic biochemistry, 2023, Volume: 249

    Topics: Animals; Cobalt; Coordination Complexes; Copper; DNA; Humans; Ligands; Mice; Neoplasms; Phenylalanine; Schiff Bases

2023
Assessing the effectiveness of fluorinated and α-methylated 3-boronophenylalanine for improved tumor-specific boron delivery in boron neutron capture therapy.
    Bioorganic chemistry, 2024, Volume: 142

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Humans; Neoplasms; Phenylalanine; Tissue Distribution; Water

2024
Application of Nitroimidazole-Carbobane-Modified Phenylalanine Derivatives as Dual-Target Boron Carriers in Boron Neutron Capture Therapy.
    Molecular pharmaceutics, 2020, 01-06, Volume: 17, Issue:1

    Topics: Animals; Boranes; Boron Compounds; Boron Neutron Capture Therapy; Cell Hypoxia; Cell Line, Tumor; Humans; Mice; Nanoparticles; Neoplasms; Nitroimidazoles; Phenylalanine; Tissue Distribution; Xenograft Model Antitumor Assays

2020
Poly(vinyl alcohol) boosting therapeutic potential of
    Science advances, 2020, Volume: 6, Issue:4

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Energy Metabolism; Humans; Mass Spectrometry; Mice; Neoplasms; Phenylalanine; Polyvinyl Alcohol; Radiation-Sensitizing Agents; Signal Transduction; Tissue Distribution; Xenograft Model Antitumor Assays

2020
YC-1 sensitizes the antitumor effects of boron neutron capture therapy in hypoxic tumor cells.
    Journal of radiation research, 2020, Jul-06, Volume: 61, Issue:4

    Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Large Neutral Amino Acid-Transporter 1; MCF-7 Cells; Neoplasms; Neutrons; Oxygen; Phenylalanine; Radiation-Sensitizing Agents; RNA, Small Interfering

2020
Implications of radiation microdosimetry for accelerator-based boron neutron capture therapy: a radiobiological perspective.
    The British journal of radiology, 2020, Volume: 93, Issue:1111

    Topics: Boranes; Boron Compounds; Boron Neutron Capture Therapy; Fluorodeoxyglucose F18; Humans; Monte Carlo Method; Neoplasms; Phenylalanine; Radiobiology; Relative Biological Effectiveness

2020
Mechanistic Modeling of the Relative Biological Effectiveness of Boron Neutron Capture Therapy.
    Cells, 2020, 10-15, Volume: 9, Issue:10

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Radiation; Humans; Linear Energy Transfer; Monte Carlo Method; Neoplasms; Phenylalanine; Radiometry; Radiotherapy, Conformal; Receptor, ErbB-2; Relative Biological Effectiveness; Trastuzumab

2020
Construction of Boronophenylalanine-Loaded Biodegradable Periodic Mesoporous Organosilica Nanoparticles for BNCT Cancer Therapy.
    International journal of molecular sciences, 2021, Feb-24, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Boron Compounds; Cell Proliferation; Humans; Metal Nanoparticles; Neoplasms; Organosilicon Compounds; Phenylalanine; Tumor Cells, Cultured

2021
Synthesis and biological evaluation of N-(carbobenzyloxy)-l-phenylalanine and N-(carbobenzyloxy)-l-aspartic acid-β-benzyl ester derivatives as potent topoisomerase IIα inhibitors.
    Bioorganic & medicinal chemistry, 2017, 06-15, Volume: 25, Issue:12

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Aspartic Acid; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; HeLa Cells; Humans; Molecular Docking Simulation; Neoplasms; Phenylalanine; Structure-Activity Relationship; Topoisomerase II Inhibitors

2017
Amphiphilic Peptide Nanorods Based on Oligo-Phenylalanine as a Biocompatible Drug Carrier.
    Bioconjugate chemistry, 2017, 09-20, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Cell Line, Tumor; Curcumin; Drug Carriers; HeLa Cells; Hemolysis; Humans; Nanotubes; Neoplasms; Oligopeptides; Phenylalanine; Surface-Active Agents; Zebrafish

2017
IL4-induced gene 1 is secreted at the immune synapse and modulates TCR activation independently of its enzymatic activity.
    European journal of immunology, 2018, Volume: 48, Issue:1

    Topics: CD28 Antigens; Cell Communication; Cell Differentiation; Cell Proliferation; Humans; Immunosuppression Therapy; Interleukin-4; L-Amino Acid Oxidase; Lymphocyte Activation; Macrophages; Neoplasms; Neutrophils; Phenylalanine; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tumor Escape; ZAP-70 Protein-Tyrosine Kinase

2018
Anticancer Activity of Resorcinarene-PAMAM-Dendrimer Conjugates of Flutamide.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Calixarenes; Cell Line, Tumor; Cell Proliferation; Dendrimers; Drug Carriers; Flutamide; Humans; Models, Molecular; Neoplasms; Phenylalanine

2018
A Switchable Site-Specific Antibody Conjugate.
    ACS chemical biology, 2018, 04-20, Volume: 13, Issue:4

    Topics: Animals; Antibodies; Binding Sites; Codon, Terminator; Genes, Switch; Humans; Immunoconjugates; Immunoglobulin Fab Fragments; Immunologic Factors; Neoplasms; Peptides; Phenylalanine

2018
Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.
    Nano letters, 2019, 01-09, Volume: 19, Issue:1

    Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Elastin; Humans; Ligands; Micelles; Nanoparticles; Neoplasms; Peptides; Phenylalanine

2019
Novel
    Molecular pharmaceutics, 2019, 08-05, Volume: 16, Issue:8

    Topics: Animals; Cell Line, Tumor; Diagnosis, Differential; Fluorine Radioisotopes; Humans; Injections, Intravenous; Large Neutral Amino Acid-Transporter 1; Male; Mice; Neoplasms; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays

2019
The immunogenicity of a novel cytotoxic T lymphocyte epitope from tumor antigen PL2L60 could be enhanced by 4-chlorophenylalanine substitution at position 1.
    Cancer immunology, immunotherapy : CII, 2013, Volume: 62, Issue:11

    Topics: Alternative Splicing; Amino Acid Sequence; Amino Acid Substitution; Animals; Antigens, Neoplasm; Argonaute Proteins; Blotting, Western; Cell Line; Cytotoxicity, Immunologic; Epitopes, T-Lymphocyte; Gene Expression Regulation, Neoplastic; HLA-A2 Antigen; HT29 Cells; Humans; Interferon-gamma; MCF-7 Cells; Mice; Mice, Transgenic; Neoplasms; Peptides; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Cytotoxic

2013
Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Alkyl and Aryl Transferases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Enzyme Inhibitors; Humans; Liposomes; Neoplasms; Phenylalanine; Protein Prenylation; Sulfonamides

2015
Design, synthesis and biological evaluation of novel asperphenamate derivatives.
    European journal of medicinal chemistry, 2016, Mar-03, Volume: 110

    Topics: Antineoplastic Agents; Autophagy; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Humans; MCF-7 Cells; Neoplasms; Phenylalanine; Structure-Activity Relationship

2016
Simultaneous Time-Dependent Surface-Enhanced Raman Spectroscopy, Metabolomics, and Proteomics Reveal Cancer Cell Death Mechanisms Associated with Gold Nanorod Photothermal Therapy.
    Journal of the American Chemical Society, 2016, 11-30, Volume: 138, Issue:47

    Topics: Cell Death; Cell Line, Tumor; Gold; Humans; Metabolomics; Nanotubes; Neoplasms; Particle Size; Phenylalanine; Phototherapy; Proteomics; Spectrum Analysis, Raman; Surface Properties; Time Factors

2016
An international dosimetry exchange for BNCT part II: computational dosimetry normalizations.
    Medical physics, 2008, Volume: 35, Issue:12

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Clinical Trials as Topic; Humans; Isotopes; Neoplasms; Phantoms, Imaging; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Reproducibility of Results; Software; Treatment Outcome

2008
Positron emission tomography and [18F]BPA: a perspective application to assess tumour extraction of boron in BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Humans; Isotopes; Lymphatic Metastasis; Melanoma; Models, Biological; Neoplasms; Phenylalanine; Positron-Emission Tomography; Prognosis; Radiation-Sensitizing Agents; Tomography, X-Ray Computed

2009
Comparison of BNCT and GdNCT efficacy in treatment of canine cancer.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Animals; Bone Neoplasms; Boron Compounds; Boron Neutron Capture Therapy; Combined Modality Therapy; Dog Diseases; Dogs; Gadolinium; Humans; Melanoma; Mouth Neoplasms; Neoplasms; Neutron Capture Therapy; Osteosarcoma; Phenylalanine

2009
Synthesis and evaluation of a novel liposome containing BPA-peptide conjugate for BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Drug Delivery Systems; Humans; Isotopes; Lipopeptides; Liposomes; Membrane Potentials; Neoplasms; Particle Size; Phenylalanine; Radiation-Sensitizing Agents; tat Gene Products, Human Immunodeficiency Virus

2009
Novel aminopeptidase N (APN/CD13) inhibitors derived from 3-phenylalanyl-N'-substituted-2,6-piperidinedione.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Antineoplastic Agents; CD13 Antigens; Cell Proliferation; HL-60 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasms; Phenylalanine; Piperidones; Protease Inhibitors; Structure-Activity Relationship; Swine

2010
Structure-based optimization of click-based histone deacetylase inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxamic Acids; Models, Molecular; Neoplasms; Phenylalanine; Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Triazoles; Vorinostat

2011
Log-scale dose response of inhibitors on a chip.
    Analytical chemistry, 2011, Aug-15, Volume: 83, Issue:16

    Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Kinetics; Lab-On-A-Chip Devices; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Microchip Analytical Procedures; Neoplasms; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes

2011
Photodynamic anticancer activities of water-soluble C(60) derivatives and their biological consequences in a HeLa cell line.
    Chemico-biological interactions, 2012, Jan-05, Volume: 195, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arginine; Caspase 3; Catalase; Cell Survival; Folic Acid; Fullerenes; Glutathione Peroxidase; HeLa Cells; Humans; Light; Malondialdehyde; Membrane Potential, Mitochondrial; Neoplasms; Phenylalanine; Photochemotherapy; Reactive Oxygen Species; Superoxide Dismutase; Water

2012
The vascular disrupting agent STA-9584 exhibits potent antitumor activity by selectively targeting microvasculature at both the center and periphery of tumors.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Survival; Dogs; Female; Heart; Hemodynamics; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Isoxazoles; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Microcirculation; Neoplasms; Neovascularization, Pathologic; Phenylalanine; Rabbits; Regional Blood Flow; Tubulin Modulators; Xenograft Model Antitumor Assays

2012
Induced radioactivity in the blood of cancer patients following Boron Neutron Capture Therapy.
    Journal of radiation research, 2013, Jul-01, Volume: 54, Issue:4

    Topics: Blood; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Deuterium Oxide; Equipment Design; Gamma Rays; Germanium; Humans; Lung; Neck; Neoplasms; Neutrons; Phenylalanine; Radiometry; Radiotherapy Dosage; Regression Analysis; Skin; Sodium Isotopes; Sulfhydryl Compounds

2013
Modified dipeptide-based nanoparticles: vehicles for targeted tumor drug delivery.
    Nanomedicine (London, England), 2013, Volume: 8, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Dipeptides; Doxorubicin; Drug Delivery Systems; Female; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Phenylalanine

2013
Studies on the anti-tumour activity of p-di-(2-chloroethyl) aminophenylalanine (sarcolysine).
    Lancet (London, England), 1955, Jul-23, Volume: 269, Issue:6882

    Topics: Melphalan; Neoplasms; Phenylalanine; Sarcoma; Sarcoma, Experimental

1955
[Effect of ribonuclease on the incorporation of adenine and phenylalanine in ascites cells in vitro].
    Archives internationales de physiologie et de biochimie, 1956, Volume: 64, Issue:1

    Topics: Adenine; Ascites; Biochemical Phenomena; DNA; Endonucleases; In Vitro Techniques; Neoplasms; Phenylalanine; Ribonucleases; RNA

1956
[Clinical study of the antineoplastic effect of DL-p-bis(beta-chloroethyl) aminophenylalanine].
    Minerva medica, 1956, Aug-11, Volume: 47, Issue:63-64

    Topics: Animals; Antineoplastic Agents; Humans; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine; Sarcoma

1956
[Experience in treating seminoma of the testes and its metastases with sarcolysin].
    Voprosy onkologii, 1956, Volume: 2, Issue:3

    Topics: Dysgerminoma; Female; Humans; Male; Melphalan; Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Phenylalanine; Seminoma; Testicular Neoplasms; Testis

1956
[A new chemotherapeutic agent for control of malignant tumors: p-di-(-2-chloroethyl)-aminophenylanine (sarcolysine)].
    Der Krebsarzt, 1956, Volume: 11, Issue:6

    Topics: Antineoplastic Agents; Humans; Melphalan; Neoplasms; Phenylalanine

1956
[Clinical observations on the use of p-bis-(beta-chloroethyl) aminophenylalanine in the treatment of reticulosarcomatosis and lymphosarcomatosis].
    Haematologica, 1956, Volume: 41, Issue:Suppl

    Topics: Antineoplastic Agents; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Phenylalanine; Sarcoma

1956
[Treatment of neoplasms with a phenylalanine derivative of nitrogen mustard].
    La Semana medica, 1958, Jan-23, Volume: 112, Issue:4

    Topics: Humans; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine

1958
[Clinical trials of mechlorethamine-N-oxide in therapy of tumors].
    Munchener medizinische Wochenschrift (1950), 1958, May-09, Volume: 100, Issue:19

    Topics: Mannitol; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Oxides; Phenylalanine

1958
[Anti-tumor activity of optic isomers of sarcolysin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1958, Volume: 46, Issue:9

    Topics: Isomerism; Mechlorethamine; Melphalan; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine

1958
Treatment of melanoma by isolation-perfusion technique.
    Journal of the American Medical Association, 1959, Jan-24, Volume: 169, Issue:4

    Topics: Humans; Leg; Mechlorethamine; Melanoma; Neoplasms; Nitrogen Mustard Compounds; Perfusion; Phenylalanine

1959
Meta-bis-(2-chloroethylamino)-dL-phenylalanine in the treatment of mouse tumors.
    Cancer research, 1960, Volume: 20

    Topics: Animals; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine

1960
[On inclusion of C14-labeled phenylalanine into the proteins of sarcoma 45 and the normal organs of rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1961, Volume: 52

    Topics: Animals; Biochemical Phenomena; Neoplasms; Phenylalanine; Proteins; Rats; Sarcoma

1961
[Repeated remissions in a case of beta-plasmocytoma; variations in the blood protein picture during p-bis(2-chloroethyl)-aminophenylalanine therapy].
    Minerva medica, 1959, Jul-21, Volume: 50

    Topics: Blood Proteins; Humans; Multiple Myeloma; Neoplasms; Phenylalanine; Plasma Cells; Plasmacytoma

1959
[The effect of sarcolysin and dopan on the biosynthesis of pyrimidines of nucleic acid in transplanted tumors and tissues of the recipient organism].
    Biulleten' eksperimental'noi biologii i meditsiny, 1960, Volume: 49

    Topics: Mechlorethamine; Melphalan; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nucleic Acids; Phenylalanine; Pyrimidines; Uracil Mustard

1960
Nitrogen and phenylalanine mustard. Use in women with intrauterine cancer.
    American journal of obstetrics and gynecology, 1962, Feb-15, Volume: 83

    Topics: Female; Humans; Mechlorethamine; Melphalan; Neoplasms; Nitrogen; Nitrogen Mustard Compounds; Phenylalanine; Uterine Neoplasms

1962
[Phenylalanine hydroxylase activity in hepatomas and livers of normal and tumor-bearing animals].
    Voprosy onkologii, 1961, Volume: 7(9)

    Topics: Animals; Carcinoma, Hepatocellular; Enzymes; Liver; Liver Neoplasms; Neoplasms; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine

1961
Effects of amino acids, analogs, and certain other agents in relation to tyrosine transport in sarcoma 37 ascites cells.
    Cancer research, 1962, Volume: 22

    Topics: Amino Acids; Animals; Ascites; Azides; Cyanides; Iodoacetates; Malonates; Neoplasms; Nitrophenols; Organic Chemicals; Phenylalanine; Sarcoma; Sarcoma 37; Sarcoma, Experimental; Tyrosine

1962
The incorporation of phenylalanine-C14 into the proteins of sarcoma 45 and of the normal organs of rats.
    Biulleten' eksperimental'noi biologii i meditsiny, 1962, Volume: 52

    Topics: Animals; Biochemical Phenomena; Neoplasms; Phenylalanine; Proteins; Rats; Sarcoma

1962
Tumour chemotherapy. V. Synthesis of some o-substituted-p-[bis-(2-chloroethylamino]-phenylalanine and test of antitumour action.
    Scientia Sinica, 1962, Volume: 11

    Topics: Antineoplastic Agents; Neoplasms; Phenylalanine

1962
Tumor chemotherapy. VII. Synthesis of p-, m- and o-[bis-(2-chloroethyl)-aminoethyl]-phenylalanine dihydrochloride and their antitumour action.
    Scientia Sinica, 1962, Volume: 11

    Topics: Antineoplastic Agents; Neoplasms; Neoplasms, Experimental; Phenylalanine

1962
L-PHENYLALANINE MUSTARD AS A TREATMENT FOR METASTATIC OSTEOGENIC SARCOMA IN CHILDREN.
    The Journal of pediatrics, 1963, Volume: 63

    Topics: Bone Marrow Diseases; Bone Neoplasms; Child; Humans; Lung Neoplasms; Mustard Plant; Neoplasm Metastasis; Neoplasms; Nitrogen Mustard Compounds; Osteosarcoma; Phenylalanine; Radiography, Thoracic; Sarcoma; Toxicology

1963
[THE EFFECT OF P-FLUORPHENYLALANINE ON THE REPRODUCTION OF VACCINIA VIRUS IN HELA CELLS].
    Archiv fur die gesamte Virusforschung, 1963, Aug-26, Volume: 13

    Topics: DNA; DNA, Viral; Electrons; HeLa Cells; Humans; Inclusion Bodies; Microscopy; Microscopy, Electron; Neoplasms; Phenylalanine; Tissue Culture Techniques; Vaccinia virus; Virus Cultivation

1963
[STUDIES ON ANTITUMOR DRUGS. VIII. THE ANTITUMOR EFFECT OF THE ETHYL ESTER OF N-FORMYL-SARCOLYSIN- PHENYLALANINE ON EXPERIMENTAL TUMORS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1963, Volume: 10

    Topics: Animals; Antineoplastic Agents; Haplorhini; Mice; Neoplasms; Pharmacology; Phenylalanine; Research; Retinitis Pigmentosa; Sarcoma; Sarcoma, Yoshida

1963
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Nov-04, Volume: 257

    Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine

1963
METABOLIC ADAPTATIONS IN RAT HEPATOMAS. VI. SUBSTRATE-HORMONE RELATIONSHIPS IN TRYPTOPHAN PYRROLASE INDUCTION.
    Cancer research, 1964, Volume: 24

    Topics: Adrenalectomy; Carbon Isotopes; Carcinoma, Hepatocellular; Cortisone; Hypophysectomy; Liver; Liver Neoplasms; Methionine; Neoplasms; Neoplasms, Experimental; Oxygenases; Phenylalanine; Portacaval Shunt, Surgical; Proteins; Rats; Research; RNA; RNA, Neoplasm; Tryptophan; Tryptophan Oxygenase

1964
[INCORPORATION IN VITRO OF PHENYLALANINE-U-C-14 IN ASCITES CELLS OF I.R.E. RETICULOSARCOMA].
    Bollettino della Societa italiana di biologia sperimentale, 1963, Oct-15, Volume: 39

    Topics: Animals; Ascites; Carbon Isotopes; In Vitro Techniques; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Phenylalanine; Sarcoma; Sarcoma, Experimental

1963
[EARLY DIAGNOSIS AND MEDICAL THERAPY OF MALIGNANT TUMORS].
    Il Cancro, 1963, Volume: 16

    Topics: Antineoplastic Agents; Busulfan; Colchicine; Early Diagnosis; Hodgkin Disease; Mechlorethamine; Mercaptopurine; Neoplasms; Phenylalanine; Podophyllum; Triethylenemelamine; Vinblastine

1963
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
    Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51

    Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research

1964
[CHEMOTHERAPY OF CANCER. V. SYNTHESIS OF SEVERAL PHENYLALANINES CONTAINING BIS-(2-CHLOROETHYL)AMINO GROUP].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1964, Volume: 11

    Topics: Chemistry, Pharmaceutical; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine; Research

1964
EVIDENCE FOR MESSENGER ACTIVITY OF ALIEN RIBONUCLEIC ACID IN CHICK CELLS.
    National Cancer Institute monograph, 1964, Volume: 13

    Topics: Chick Embryo; Dactinomycin; Leucine; Metabolism; Neoplasms; Nucleotides; Pharmacology; Phenylalanine; Proteins; RNA; RNA, Bacterial; RNA, Messenger; RNA, Neoplasm

1964
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
HISTOPATHOLOGICAL CHANGES IN MALIGNANT MELANOMA AND NORMAL TISSUES FOLLOWING REGIONAL PERFUSION WITH L-PHENYLALANINE MUSTARD (L-SARCOLYSIN).
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Chemotherapy, Cancer, Regional Perfusion; Extracorporeal Circulation; Lymphatic Metastasis; Melanoma; Melphalan; Mice; Mustard Plant; Neoplasms; Neoplasms, Experimental; Pharmacology; Phenylalanine; Research

1964
SYNTHESIS OF N,N-BIS(2-CHLOROETHYL)-DL-PHENYLALANINE HYDROCHLORIDE.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Adenocarcinoma; Animals; Carcinoma; Carcinoma 256, Walker; Chemistry, Pharmaceutical; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Pharmacology; Phenylalanine; Research; Sarcoma 180

1963
HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE IN NEOPLASTIC MAST CELLS OF THE MOUSE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Hydroxylation; Indoles; Mast Cells; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Research; Tryptophan; Tyrosine

1964
TREATMENT OF LEUKAEMIA BY AMINOACID IMBALANCE.
    Lancet (London, England), 1965, Feb-06, Volume: 1, Issue:7380

    Topics: Amino Acids; Child; Diet; Diet Therapy; Dietary Proteins; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocytes; Neoplasms; Phenylalanine; Tyrosine

1965
THE BIOCHEMICAL MECHANISM OF ACTION OF L-PHENYLALANINE MUSTARD. I. DISTRIBUTION OF L-PHENYLALANINE MUSTARD-H3 IN TUMOR-BEARING RATS.
    Cancer research, 1965, Volume: 25

    Topics: Animals; Bone Marrow; Carcinoma 256, Walker; Chromatography; DNA; Intestines; Kidney; Liver; Melphalan; Metabolism; Muscles; Mustard Plant; Neoplasms; Pharmacology; Phenylalanine; Plasma; Rats; Research; Spleen; Thymus Gland; Tritium; Tyrosine

1965
STUDIES OF EPIDERMAL PROTEIN METABOLISM. 3. PROTEIN SYNTHESIS IN AN EPIDERMAL CARCINOMA IN VIVO AND IN VITRO.
    The Journal of investigative dermatology, 1965, Volume: 44

    Topics: Carbon Isotopes; Cricetinae; Histological Techniques; In Vitro Techniques; Leucine; Liver; Magnesium; Microsomes; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Pharmacology; Phenylalanine; Proteins; Research; Ribosomes; Skin Neoplasms; Uracil Nucleotides

1965
FATAL HOMOTRANSPLANTED MELANOMA: A CASE REPORT.
    Cancer, 1965, Volume: 18

    Topics: Humans; Melanoma; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Pathology; Phenylalanine; Transplantation, Homologous

1965
DIFFERENTIAL EFFECTS OF INHIBITORS ON THE STEPS LEADING TO THE FORMATION OF SV40 TUMOR AND VIRUS ANTIGENS.
    The Journal of experimental medicine, 1965, Jun-01, Volume: 121

    Topics: Animals; Antigens; Antigens, Viral; Antimetabolites; Chlorocebus aethiops; Complement Fixation Tests; Dactinomycin; DNA, Viral; Floxuridine; Fluorescence; Fluorescent Antibody Technique; Fluorouracil; Idoxuridine; Microscopy; Microscopy, Fluorescence; Mitomycin; Neoplasms; Nucleosides; Pharmacology; Phenylalanine; Puromycin; Research; Simian virus 40; Tissue Culture Techniques; Virus Cultivation

1965
L-PHENYLALANINE MUSTARD (NSC-8806) IN UNCOMMON MALIGNANT DISEASE IN CHILDREN.
    Cancer chemotherapy reports, 1965, Volume: 45

    Topics: Child; Humans; Melphalan; Mustard Plant; Neoplasms; Phenylalanine; Toxicology

1965
[ANTINEOPLASTIC ACTIVITY OF O-BIS(2-CHLOROETHYL) AMINO-DL-PHENYLALANINE (ORTHOSARCOLYSIN)].
    Voprosy onkologii, 1964, Volume: 10

    Topics: Antineoplastic Agents; Melphalan; Neoplasms; Neoplasms, Experimental; Pharmacology; Phenylalanine; Rats; Research; Toxicology

1964
[Anti-tumor action of p-bis (chloroethyl) aminophenylalanine (sarcolysin)].
    Biulleten' eksperimental'noi biologii i meditsiny, 1955, Volume: 39, Issue:1

    Topics: Animals; Melphalan; Neoplasms; Neoplasms, Experimental; Phenylalanine

1955
Some experimental and clinical data on the sarcolysin peptides.
    British medical journal, 1960, Jan-09, Volume: 1, Issue:5166

    Topics: Melphalan; Neoplasms; Peptides; Phenylalanine

1960
[The effect of sarocolysin on regeneration in amphibia and tumors in mice in conditions of light hypothermia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1960, Volume: 49

    Topics: Amphibians; Animals; Hypothermia; Hypothermia, Induced; Light; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Regeneration

1960
Effects of beta-3-thienylalanine and deoxypyridoxine on the tumor growth. II. Effects on the tumor-bearing host.
    Laboratory investigation; a journal of technical methods and pathology, 1962, Volume: 11

    Topics: Animals; Neoplasms; Neoplasms, Experimental; Phenylalanine; Vitamin B 6

1962
Salt inhibition and enhancement of cytochrome, succinic, and dopa oxidase systems of mouse melanomas.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1950, Volume: 75, Issue:3

    Topics: Cytochromes; Melanoma; Monophenol Monooxygenase; Neoplasms; Oxidoreductases; Phenylalanine; Salts

1950
Study on the compounds containing 19F and 10B atoms in a single molecule for the application to MRI and BNCT.
    Bioorganic & medicinal chemistry, 2006, May-15, Volume: 14, Issue:10

    Topics: Animals; Boron; Boron Neutron Capture Therapy; Boronic Acids; Cell Line, Tumor; Cells, Cultured; Contrast Media; Fluorine; HeLa Cells; Humans; Isotopes; Magnetic Resonance Imaging; Molecular Structure; Neoplasms; Phenylalanine; Rats

2006
Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
    Cancer science, 2006, Volume: 97, Issue:7

    Topics: Adenoviridae; Amino Acid Substitution; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Genetic Therapy; Humans; Mice; Mutation; Neoplasms; Phenylalanine; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-bcl-2; Serine; Transcription, Genetic; Transcriptional Activation; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases

2006
Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging.
    Cancer biotherapy & radiopharmaceuticals, 2006, Volume: 21, Issue:3

    Topics: Amino Acids; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Copper; Drug Design; Humans; Iodine Radioisotopes; Isotope Labeling; Models, Chemical; Neoplasms; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Temperature

2006
Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
    Molecular and cellular biology, 2007, Volume: 27, Issue:3

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Cell Nucleus; Cysteine; HeLa Cells; Humans; Mice; Molecular Sequence Data; Mutant Proteins; Mutation; Neoplasms; Phenylalanine; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-mdm2; Ribosomal Proteins; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitin; Zinc Fingers

2007
Mutations in JAK2V617F homologous domain of JAK genes are uncommon in solid tumors.
    International journal of cancer, 2007, Nov-01, Volume: 121, Issue:9

    Topics: Base Sequence; Conserved Sequence; Humans; Janus Kinase 2; Mutation; Neoplasms; Phenylalanine; Protein Structure, Tertiary; Valine

2007
Convergence of isoenzyme expression in human tumor xenografts.
    Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1980, Volume: 1, Issue:2

    Topics: Alkaline Phosphatase; Animals; Cell Line; Cricetinae; Homoarginine; Humans; Isoenzymes; Neoplasm Transplantation; Neoplasms; Phenylalanine; Stereoisomerism; Transplantation, Heterologous

1980
Determination of urinary amino acids by liquid chromatography with "dabsyl chloride".
    Clinical chemistry, 1980, Volume: 26, Issue:5

    Topics: Amino Acids; Chromatography, Liquid; Humans; Neoplasms; p-Dimethylaminoazobenzene; Phenylalanine; Phenylketonurias; Sulfones

1980
Characterization and use of an allotype-specific monoclonal antibody to placental alkaline phosphatase in the study of cancer-related phosphatase polymorphism.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Alkaline Phosphatase; Alleles; Animals; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hybridomas; Kinetics; Leucine; Mice; Mice, Inbred BALB C; Neoplasms; Phenotype; Phenylalanine; Placenta; Polymorphism, Genetic; Pregnancy

1982
[Curing trial of complicated oncologic pain by D-phenylalanine (author's transl)].
    Anesthesie, analgesie, reanimation, 1981, Volume: 38, Issue:11-12

    Topics: Affect; Aged; Analgesics; Drug Evaluation; Enkephalins; Female; Humans; Male; Middle Aged; Neoplasms; Pain, Intractable; Phenylalanine

1981
Skin sensitization with the new reagents NOPYE (4-nitro-1-cyclohexyl-3-ethoxy-2-oxo-3-pyrroline) and NOPY-L-phenylalanine.
    Journal of surgical oncology, 1980, Volume: 13, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Cross Reactions; Cyclohexanes; Dinitrochlorobenzene; Female; Guinea Pigs; Hypersensitivity, Delayed; Immunotherapy; Neoplasms; Ovalbumin; Phenylalanine; Pyrroles; Skin; Tuberculin

1980
Matrix metalloproteinase inhibitors: a novel class of anticancer agents.
    Advances in enzyme regulation, 1995, Volume: 35

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Humans; Melanoma, Experimental; Metalloendopeptidases; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes

1995
Maximum therapeutic depth in thermal neutron capture therapy.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1993, Volume: 169, Issue:1

    Topics: Boranes; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Humans; Neoplasms; Phenylalanine; Sulfhydryl Compounds

1993
Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.
    Archives of biochemistry and biophysics, 1996, Aug-01, Volume: 332, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carboxypeptidases; Cattle; Cloning, Molecular; DNA Primers; Enzyme Precursors; Enzyme Stability; Gene Expression; Humans; Kinetics; Methotrexate; Molecular Sequence Data; Neoplasms; Pancreas; Phenylalanine; Prodrugs; Rats; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Substrate Specificity; Temperature

1996
Whole body protein metabolism in children with cancer.
    Archives of disease in childhood, 1996, Volume: 75, Issue:4

    Topics: Adolescent; Amino Acids; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Kinetics; Leucine; Male; Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Tyrosine

1996
Batimastat. BB 94, collagenase inhibitors-1.
    Drugs in R&D, 1999, Volume: 1, Issue:2

    Topics: Animals; Antineoplastic Agents; Ascites; Drugs, Investigational; Humans; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Neoplasms; Phenylalanine; Pleural Effusion, Malignant; Protease Inhibitors; Thiophenes

1999
Membrane type 1 matrix metalloproteinase-associated degradation of tissue inhibitor of metalloproteinase 2 in human tumor cell lines.
    The Journal of biological chemistry, 2000, Apr-14, Volume: 275, Issue:15

    Topics: Enzyme Activation; Humans; Hydrogen-Ion Concentration; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Membrane Proteins; Metalloendopeptidases; Neoplasms; Phenylalanine; Protease Inhibitors; Recombinant Proteins; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured

2000
Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets.
    Blood, 2000, Dec-15, Volume: 96, Issue:13

    Topics: Adult; Blood Platelets; Cell Division; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Lymphokines; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; Phenylalanine; Piperidines; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Thrombin; Thrombophilia; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy.
    Nature medicine, 2001, Volume: 7, Issue:11

    Topics: Animals; Apoptosis; Hepatitis, Animal; Humans; Interferon-gamma; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms; Phenylalanine; Protease Inhibitors; Recombinant Proteins; Thiophenes; Tumor Necrosis Factor-alpha

2001
Evaluation of apoptosis and micronucleation induced by reactor neutron beams with two different cadmium ratios in total and quiescent cell populations within solid tumors.
    International journal of radiation oncology, biology, physics, 2001, Nov-01, Volume: 51, Issue:3

    Topics: Animals; Apoptosis; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Bromodeoxyuridine; Cadmium; Carcinoma, Squamous Cell; Cytochalasin B; Fluorescent Antibody Technique; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Micronucleus Tests; Neoplasms; Neutrons; Phenylalanine; Radiation Tolerance; Radiation-Sensitizing Agents; Radiobiology; Radioisotopes; Relative Biological Effectiveness; Sarcoma, Experimental; Sulfhydryl Compounds; Tumor Cells, Cultured

2001
A modified inactivation-inhibition method for determining the serum activity of alkaline phosphatase isoenzymes.
    Clinica chimica acta; international journal of clinical chemistry, 1976, May-17, Volume: 69, Issue:1

    Topics: Adult; Aged; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Evaluation Studies as Topic; gamma-Glutamyltransferase; Humans; Intestines; Isoenzymes; Liver; Liver Diseases; Methods; Middle Aged; Neoplasms; Organ Specificity; Phenylalanine

1976
[Distribution of T and B lymphocytes in children's diseases. M. Down, phenylketonuria, celiac disease and other malabsorptions, malignant tumours, chronic otitis media, and infectious mononucleosis (author's transl)].
    Casopis lekaru ceskych, 1979, Jan-19, Volume: 118, Issue:3

    Topics: Age Factors; B-Lymphocytes; Celiac Disease; Child; Down Syndrome; Humans; Infectious Mononucleosis; Leukocyte Count; Malabsorption Syndromes; Neoplasms; Phenylalanine; Phenylketonurias; T-Lymphocytes

1979
[Experimental and clinical application of amino acid imbalance for the treatment of malignant diseases, with special reference to phenylalanine imbalance (author's transl)].
    Igaku kenkyu. Acta medica, 1977, Volume: 47, Issue:4

    Topics: Adult; Amino Acids; Animals; Blood Cell Count; Carcinoma, Ehrlich Tumor; Child; Female; Humans; Leucine; Leukemia, Myeloid; Liver; Male; Mice; Neoplasm Proteins; Neoplasms; Organ Size; Phenylalanine; Phenylalanine Hydroxylase

1977
[Tumour chemotherapy. XXXIX Synthesis of 2-methyl-5-bis (beta-chloroethyl) aminophenylalanine and 2-bis (beta-chloroethyl)-aminomethyl-5-nitrophenylalanine (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1979, Volume: 14, Issue:11

    Topics: Animals; Antineoplastic Agents; Melphalan; Mice; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine

1979
On the levels of phenylalanine, tyrosine and tetrahydrobiopterin in the blood of tumor-bearing organisms.
    Cancer biochemistry biophysics, 1977, Volume: 2, Issue:2

    Topics: Animals; Biopterins; Blood Proteins; Female; Humans; Hydroxylation; Male; Neoplasms; Neoplasms, Experimental; Phenylalanine; Protein Binding; Pteridines; Rats; Tyrosine

1977
Drugs that make cancer retreat.
    Indian journal of cancer, 1976, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine; Piperazines; Prospidium; Tegafur

1976
L-leucine sensitive alkaline phosphatase isozyme from cancer tissue.
    Annals of the New York Academy of Sciences, 1975, Aug-22, Volume: 259

    Topics: Alkaline Phosphatase; Drug Stability; Edetic Acid; Female; Hot Temperature; Humans; Isoenzymes; Kinetics; Leucine; Neoplasms; Phenylalanine; Placenta; Precipitin Tests; Pregnancy

1975
Aminopeptidases and arylamidases in normal and cancer tissues in humans.
    Cancer research, 1975, Volume: 35, Issue:4

    Topics: Alanine; Amides; Aminopeptidases; Colon; Digestive System; Humans; Ileum; Kidney; Leucine; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Methionine; Naphthalenes; Neoplasms; Phenylalanine; Rectum; Stomach; Stomach Neoplasms

1975
Intracellular boron localization and uptake in cell cultures using imaging secondary ion mass spectrometry (ion microscopy) for neutron capture therapy for cancer.
    Biology of the cell, 1992, Volume: 74, Issue:1

    Topics: Animals; Boron Compounds; Cryopreservation; Mass Spectrometry; Mice; Microscopy; Neoplasms; Neutrons; Phenylalanine; Tumor Cells, Cultured; Uridine

1992
[Anticancer therapy with amino acid imbalance].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine

1991
Boron neutron capture therapy for cancer.
    Scientific American, 1990, Volume: 263, Issue:4

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage

1990
Preparation of boron-containing bovine -globulin as a model compound for a new approach to slow neutron therapy of tumors.
    Cancer research, 1972, Volume: 32, Issue:9

    Topics: Alanine; Anhydrides; Animals; Boron Compounds; Boronic Acids; Cattle; Chromatography, Gel; Dipeptides; gamma-Globulins; Methods; Neoplasms; Neutrons; Phenylalanine

1972
[Antitumor activity of nitrocaphane (AT-1258)].
    Zhonghua yi xue za zhi, 1974, Issue:11

    Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Nitrogen Mustard Compounds; Phenylalanine; Rats

1974
The potential of coenzyme Q 10 (NSC-140865) in cancer treatment.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:4

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Chick Embryo; Cricetinae; Haplorhini; Humans; Lipid Metabolism; Metabolism, Inborn Errors; Mice; Neoplasms; Peroxides; Phenylalanine; Rabbits; Rats; Sarcoma 180; Succinate Dehydrogenase; Turkeys; Tyrosine; Ubiquinone

1974
Effects of phenylalanine and related compounds on serum alkaline phosphatase assay.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 32, Issue:3

    Topics: Adult; Alkaline Phosphatase; Bone Diseases; Chemistry, Clinical; Chloramphenicol; Fenclonine; Humans; Liver Diseases; Melphalan; Neoplasms; Phenylalanine; Phenylketonurias; Stereoisomerism

1971
Clinical application of phosphohydrolase measurements in cancer.
    Annals of the New York Academy of Sciences, 1969, Oct-14, Volume: 166, Issue:2

    Topics: Acid Phosphatase; Alkaline Phosphatase; Bile Acids and Salts; Bone Neoplasms; Electrophoresis; Histidine; Humans; Hydrogen-Ion Concentration; Kidney; Liver; Male; Neoplasms; Nucleotidases; Organ Specificity; Phenylalanine; Phosphoric Monoester Hydrolases; Prostatic Neoplasms

1969
New diet 'starves' cancer cells.
    IMJ. Illinois medical journal, 1967, Volume: 132, Issue:3

    Topics: Diet Therapy; Humans; Neoplasms; Phenylalanine

1967
Peptichemio in the therapy of malignancies (phase-I-study). The evaluation committee.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 10, Issue:3

    Topics: Blood Platelets; Bone Marrow Diseases; Cell Division; Cell Membrane; Chromosomes; Drug Evaluation; Humans; Immunosuppressive Agents; Lymphoma; Microscopy, Electron; Neoplasms; Nitrogen Mustard Compounds; Peptides; Phenylalanine; Thymidine; Time Factors; Tritium

1974
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
    Oncology, 1974, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Cattle; Depression, Chemical; DNA, Neoplasm; Female; Fluorouracil; Humans; In Vitro Techniques; Iodoacetates; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; Mice; Neoplasms; Phenylalanine; Succinate Dehydrogenase; Thymidine; Tritium

1974
Problems of in-vitro incubation with radioactive precursors.
    Folia morphologica, 1973, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Agents; Cytidine; Humans; Neoplasms; Phenylalanine; Proline; Rats; Thymidine; Tritium

1973
Presented before the OSHA hearings regarding proposed permanent standard on certain carcinogens.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1974, Volume: 16, Issue:5

    Topics: Animals; Biphenyl Compounds; Carcinogens; Chemical Industry; Chlorine; Cricetinae; Environmental Exposure; Female; Follow-Up Studies; Humans; Lethal Dose 50; Male; Mice; Neoplasms; Nitrogen Mustard Compounds; Occupational Diseases; Phenols; Phenylalanine; Phenylbutyrates; Rabbits; Rats; Sampling Studies; Statistics as Topic; United States; Urinary Bladder Neoplasms

1974
Transfer RNA methylases and cancer.
    Nature, 1970, Dec-26, Volume: 228, Issue:5278

    Topics: Animals; Carbon Isotopes; Carcinogens; Cell Differentiation; Chromatography, Ion Exchange; Escherichia coli; Ethionine; Guanine; Humans; Kidney Neoplasms; Liver Regeneration; Methionine; Methylation; Morphogenesis; Neoplasms; Nitrosamines; Phenylalanine; Protein Biosynthesis; Rats; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Transferases

1970
The clinical usefulness of alkaline phosphatase isoenzyme determinations.
    American journal of clinical pathology, 1972, Volume: 57, Issue:5

    Topics: Alkaline Phosphatase; Bone Diseases; Clinical Enzyme Tests; Electrophoresis, Disc; Hot Temperature; Intestinal Diseases; Isoenzymes; Kidney Diseases; Liver Diseases; Methods; Neoplasms; Phenylalanine; Tissue Extracts; Urea

1972
[Concentration changes of free amino acids in blood plasma of patients under radiotherapy. (With reference to statistical results)].
    Strahlentherapie, 1972, Volume: 143, Issue:4

    Topics: Alanine; Amino Acids; Bronchial Neoplasms; Carcinoma; Cobalt Isotopes; Dysgerminoma; Esophageal Neoplasms; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leucine; Male; Neoplasms; Phenylalanine; Proline; Radiation Injuries; Sex Factors; Statistics as Topic; Tyrosine; Urinary Bladder Neoplasms; Valine

1972
Patterns of amino-acid inhibition of alkaline phosphatases as an aid in cancer diagnosis.
    Oncology, 1971, Volume: 25, Issue:3

    Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acids; Animals; Arginine; Colonic Neoplasms; Female; Humans; In Vitro Techniques; Isoenzymes; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Phenylalanine; Rats; Valine

1971
The early interference of liver carcinogens with protein synthesis and its possible bearing on the problem of tumor induction.
    Biochemical pharmacology, 1971, Volume: 20, Issue:5

    Topics: Acridines; Animals; Carbon Isotopes; Carbon Tetrachloride; Carcinogens; Centrifugation, Density Gradient; Chromatography, Gel; Electrophoresis, Disc; In Vitro Techniques; Liver; Macromolecular Substances; Mice; Microsomes, Liver; Neoplasms; Orotic Acid; Peptide Chain Initiation, Translational; Phenylalanine; Potassium Chloride; Protein Biosynthesis; Rats; Ribosomes; RNA; RNA, Messenger

1971
Clinical application of alkaline phosphatase isoenzyme analysis.
    Annals of the New York Academy of Sciences, 1969, Oct-14, Volume: 166, Issue:2

    Topics: Alkaline Phosphatase; Bile Acids and Salts; Bone Neoplasms; Electrophoresis; Histidine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Isoenzymes; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Neoplasms; Nucleotidases; Phenylalanine; Protein Denaturation

1969
Studies in histochemistry. LXXIX. Properties of tryptophan hydroxylase from neoplastic murine mast cells.
    The Journal of biological chemistry, 1966, Jan-10, Volume: 241, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mast Cells; Mice; Mixed Function Oxygenases; Neoplasms; Phenylalanine; Serotonin; Tryptophan

1966
Alkaline phosphatase in meningiomas.
    Cancer, 1970, Volume: 26, Issue:1

    Topics: Alkaline Phosphatase; Central Nervous System Diseases; Chemical Phenomena; Chemistry, Physical; Hot Temperature; Humans; Meningioma; Neoplasms; Phenylalanine; Urea

1970
Automated differential isoenzyme analysis. I. L-phenylalanine-sensitive isoenzymes of human serum alkaline phosphatase.
    Enzymologia, 1967, Aug-31, Volume: 33, Issue:2

    Topics: Alkaline Phosphatase; Autoanalysis; Bone Diseases; Female; Humans; Indicators and Reagents; Intestinal Absorption; Intestines; Isoenzymes; Liver Diseases; Methods; Neoplasms; Phenylalanine; Placenta; Pregnancy; Spectrophotometry

1967
Dietary amino acid and nucleic acid imbalance leading to altered tumour frequency in the adult housefly, Musca domestica.
    Journal of insect physiology, 1968, Volume: 14, Issue:2

    Topics: Aging; Amino Acids; Animals; Dietary Proteins; Houseflies; Neoplasms; Nucleic Acids; Phenylalanine

1968
[Relations between phenylalanine and cancerous cells].
    Minerva medica, 1968, Oct-03, Volume: 59, Issue:79

    Topics: Amino Acids; Animals; Diet Therapy; Humans; Neoplasms; Phenylalanine; Proteins; Tyrosine

1968
[A novel synthesis of o-methoxy-p-[bis-(2-chloroethyl)-amino]-phenylalanine].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1966, Volume: 13, Issue:6

    Topics: Chemistry, Pharmaceutical; Humans; Neoplasms; Phenylalanine

1966