phenylalanine has been researched along with Long QT Syndrome in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Goto, A; Ikeda, N; Izumi-Nakaseko, H; Kambayashi, R; Kumagai, Y; Matsuda, K; Matsumoto, A; Oikawa, I; Sugiyama, A; Takei, Y | 1 |
| Carter, LP; Chen, D; Lee, L; Swearingen, D; Zomorodi, K | 1 |
| Chen, XL; Du, R; Guan, SM; Kang, CL; Ke, QM; Li, W; Song, ZF; Tian, L; Wang, B; Wang, QF; Xu, QM; Yang, JG; Zhang, SY | 1 |
| Cui, CC; Li, HB; Shu, J; Sun, CF; Wang, DQ; Xue, XL; Yang, HT; Zhang, AF | 1 |
| Hong, HK; Jo, SH; Lee, BH; Park, MH | 1 |
| Kim, EJ; Kim, KS; Park, SJ | 1 |
2 trial(s) available for phenylalanine and Long QT Syndrome
| Article | Year |
|---|---|
Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects.
Topics: Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Fluoroquinolones; Healthy Volunteers; Heart Rate; Humans; Integrin alpha4; Japan; Long QT Syndrome; Moxifloxacin; Phenylalanine; Quinazolinones | 2022 |
A Randomized, Double-Blind, Placebo- and Positive-Controlled, 4-Period Crossover Study of the Effects of Solriamfetol on QTcF Intervals in Healthy Participants.
Topics: Adrenergic Uptake Inhibitors; Adult; Carbamates; Cross-Over Studies; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Phenylalanine; Young Adult | 2021 |
4 other study(ies) available for phenylalanine and Long QT Syndrome
| Article | Year |
|---|---|
Congenital long QT syndrome caused by the F275S KCNQ1 mutation: mechanism of impaired channel function.
Topics: Animals; Cell Line; Endoplasmic Reticulum; Humans; KCNQ1 Potassium Channel; Long QT Syndrome; Mutation, Missense; Phenylalanine; Protein Transport; Serine | 2009 |
HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Blotting, Western; Cell Line; Cytosine; Electrocardiography; Endoplasmic Reticulum; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heterozygote; Humans; Leucine; Long QT Syndrome; Microscopy, Confocal; Molecular Sequence Data; Mutation, Missense; Patch-Clamp Techniques; Pedigree; Phenylalanine; Potassium Channels, Voltage-Gated; Protein Subunits; Protein Transport; Thymine; Transfection | 2009 |
Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Desipramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Long QT Syndrome; Mutation; Oocytes; Phenylalanine; Protein Structure, Tertiary; Tyrosine; Xenopus | 2010 |
Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656.
Topics: Brompheniramine; Cell Line; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Humans; Kinetics; Long QT Syndrome; Membrane Potentials; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Potassium Channel Blockers; Protein Subunits; Risk Assessment; Transfection; Tyrosine | 2008 |