phenylalanine has been researched along with Insulin Resistance in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.54) | 18.7374 |
| 1990's | 7 (10.77) | 18.2507 |
| 2000's | 31 (47.69) | 29.6817 |
| 2010's | 24 (36.92) | 24.3611 |
| 2020's | 2 (3.08) | 2.80 |
| Authors | Studies |
|---|---|
| An, YP; Chen, JC; Huang, L; Li, YM; Lin, PC; Lin, Y; Liu, J; Sun, WW; Sun, WX; Wu, BX; Xu, W; Yuan, YY; Zhang, HL; Zhao, JY; Zhao, SM; Zhou, Q; Zhou, XW | 1 |
| Chen, L; Chen, T; Hu, J; Hua, Z; Li, S; Li, Y; Wu, D; Xu, Y; Yan, H; Zhao, R | 1 |
| Ahola-Olli, AV; Ala-Korpela, M; Auvinen, J; Havulinna, AS; Järvelin, MR; Jokelainen, J; Juonala, M; Kähönen, M; Kalimeri, M; Keinänen-Kiukaanniemi, S; Kettunen, J; Lehtimäki, T; Mustelin, L; Perola, M; Puukka, K; Raitakari, O; Salomaa, V; Würtz, P | 1 |
| Jessen, N; Kampmann, U; Møller, N; Rittig, N; Svart, MV; Voss, TS | 1 |
| Bain, JR; Ilkayeva, OR; Lowe, LP; Lowe, WL; Metzger, BE; Muehlbauer, MJ; Newgard, CB; Nodzenski, M; Reisetter, AC; Scholtens, DM; Stevens, RD | 1 |
| Bolanowski, M; Daroszewski, J; Gamian, A; Mierzchała-Pasierb, M; Rybka, J; Siomkajło, M; Stankiewicz-Olczyk, J | 1 |
| Aldámiz-Echevarría, L; Correcher, P; Couce, ML; De Castro, MJ; Fernández-Marmiesse, A; Hermida, A; Leis, R; Martínez-Olmos, M; Roca, I; Sánchez-Pintos, P; Vitoria, I | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Anderwald, CH; Bernroider, E; Brehm, A; Krebs, M; Krssak, M; Nowotny, P; Phielix, E; Roden, M; Schmid, AI | 1 |
| Kim, SS; Koide, M; Nagasawa, Y; Sawada, T; Shiotani, H; Terashita, D; Yokoyama, M | 1 |
| Jensen, MD; Liebau, F; Nair, KS; Rooyackers, O | 1 |
| Klaus, KA; Morse, DM; Nair, KS; Robinson, MM; Schimke, JM; Sohn, TS; Soop, M | 1 |
| Abdulla, H; Atherton, PJ; Idris, I; Smith, K | 1 |
| Arisawa, K; Ide, N; Kagawa, Y; Maeda, T; Ogura, K | 1 |
| Bao, Y; Chen, T; Hu, C; Huang, F; Jia, W; Ma, X; Ni, Y; Rajani, C; Zhao, A; Zheng, X | 1 |
| Liu, Y; Liu, Z; Men, L; Pi, Z; Song, F; Wei, M; Zhou, Y | 1 |
| Economopoulos, KP; Gharedaghi, MH; Gul, SS; Hamarneh, SR; Hamilton, AR; Hodin, RA; Hu, D; Huo, H; Hyoju, SK; Liu, W; Morrison, S; Munoz, AR; Phupitakphol, T; Zhang, W | 1 |
| Christiansen, B; Dominguez, H; Hermann, TS; Ihlemann, N; Kveiborg, B; Køber, L; Major-Pedersen, A; Nielsen, D; Rask-Madsen, C; Svendsen, OL; Torp-Pedersen, C | 1 |
| Dong, F; Kandadi, MR; Ren, J; Sreejayan, N | 1 |
| Dolence, EK; He, L; Li, J; Ma, H; Nair, S; Ren, J; Tong, C; Wang, J; Wang, Z; Xiao, Y; Zhao, P; Zheng, Q | 1 |
| Gao, X; Gao, Y; Li, GW; Liu, X; Pan, CY; Zhu, XX | 1 |
| Ades, PA; LeWinter, MM; Matthews, DE; Toth, MJ | 1 |
| Kajioka, T; Kitahara, Y; Miura, K; Takeuchi, M; Yamagishi, S | 1 |
| Du, M; Kandadi, MR; Ren, J; Sreejayan, N; Unnikrishnan, MK; Warrier, AK | 1 |
| Gosmanov, AR; Umpierrez, GE; Westerhaus, B | 1 |
| Bennett, C; Dasarathy, S; Duenas, C; Edmison, J; Gruca, LL; Kalhan, SC; Lopez, R; Marczewski, S | 1 |
| Biolo, G; Carli, F; Corbella, D; Di Nicola, M; Donatelli, F; Fumagalli, R; Lorini, L | 1 |
| Adams, SH | 1 |
| Adamski, J; Boeing, H; Drogan, D; Floegel, A; Fritsche, A; Häring, HU; Hrabě de Angelis, M; Illig, T; Joost, HG; Mühlenbruch, K; Peters, A; Pischon, T; Prehn, C; Roden, M; Schulze, MB; Stefan, N; Wang-Sattler, R; Yu, Z | 1 |
| Ala-Korpela, M; Kähönen, M; Kangas, AJ; Lehtimäki, T; Raitakari, OT; Rönnemaa, T; Soininen, P; Viikari, JS; Würtz, P | 1 |
| Mori, Y; Sekihara, H | 1 |
| Chinkes, DL; Gore, DC; Hart, DW; Herndon, DN; Sanford, AP; Wolf, SE | 1 |
| Yamada, K | 1 |
| Odawara, M | 1 |
| Shiba, T | 1 |
| Gore, DC; Herndon, DN; Sanford, AP; Wolf, SE; Wolfe, RR | 1 |
| Ishida, H; Kadowaki, T; Kawamori, R | 1 |
| Mamori, S; Mori, Y; Tajima, N | 1 |
| Ohyama, Y; Tomono, S; Uchiyama, T | 1 |
| Hirose, T | 1 |
| Tsujii, S | 1 |
| Kawamori, R | 1 |
| Ferrannini, E; Foley, JE; Gastaldelli, A; Mari, A; Pratley, RE | 1 |
| Gorogawa, S; Hazama, Y; Hori, M; Kaneto, H; Kato, K; Kawamori, D; Matsuhisa, M; Nakamura, Y; Ohtoshi, K; Shiraiwa, T; Yamasaki, Y; Yoshiuchi, K | 1 |
| Fujita, S; Mittendorfer, B; Rasmussen, BB; Rowe, VL; Roy, M; Volpi, E; Wolfe, RR | 1 |
| Dong, F; Li, SY; Ren, J; Sreejayan, N; Yang, X | 1 |
| Ahrén, B; Axelsen, M; Jansson, PA; Johanson, EH; Sandqvist, M; Schmelz, M; Smith, U | 1 |
| Harada, S; Ito, S; Nakaya, Y; Nomura, M | 1 |
| Bergeron, K; Chouinard, PY; Couture, Y; Davis, TA; Dombrowski, L; Dubreuil, P; Gingras, AA; Julien, P; Marette, A; Myre, A; Thivierge, MC; White, PJ | 1 |
| Kanno, Y; Ohno, Y; Suzuki, H; Takenaka, T | 1 |
| Barazzoni, R; Biolo, G; Dal Mas, V; De Cicco, M; Fantin, D; Guarnieri, G; Iapichino, G; Lorenzon, S; Paroni, R; Zanetti, M | 1 |
| Deckelbaum, LI; Louard, RJ; McNulty, PH; Young, LH; Zaret, BL | 1 |
| Biolo, G; Inchiostro, S; Orlando, R; Sergi, G; Tessari, P; Vettore, M | 1 |
| Ikemoto, T; Ishikawa, Y; Saito, MN; Takeno, H; Tani, T; Watanabe, K | 1 |
| Bohov, P; Gasperíková, D; Klimes, I; Líska, B; Mitková, A; Seböková, E; Stanek, J; Ukropec, J | 1 |
| Smits, P; Tack, CJ | 1 |
| Fickova, M; Klimes, I; Macho, L; Sebokova, E; Zorad, S | 1 |
| Kawamori, R; Nishiyama, K; Niwa, M; Shimizu, T; Uchino, H | 1 |
| Chen, W; de Souza, CJ; Dragonas, N; Gagen, K | 1 |
| Yudkin, JS | 1 |
| Asskamp, B; Eckel, J; Reinauer, H | 1 |
| Hager, SR; Kalkhoff, RK | 1 |
| Cahill, GF; Felig, P; Marliss, E | 1 |
11 review(s) available for phenylalanine and Insulin Resistance
| Article | Year |
|---|---|
Role of insulin in the regulation of human skeletal muscle protein synthesis and breakdown: a systematic review and meta-analysis.
Topics: Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Signal Transduction | 2016 |
Diabetes prevention: can insulin secretagogues do the job?
Topics: Benzamides; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Type 2; Disease Progression; Evidence-Based Medicine; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Nateglinide; Phenylalanine; Preventive Health Services; Sulfonylurea Compounds; Treatment Outcome | 2011 |
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine | 2011 |
[Adverse effects of oral hypoglycemic agents].
Topics: Acarbose; Administration, Oral; Biguanides; Cyclohexanes; Drug Interactions; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Nateglinide; Phenylalanine; Pioglitazone; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones | 2002 |
[Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus].
Topics: Acarbose; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypertension; Hypoglycemic Agents; Inositol; Insulin Resistance; Nateglinide; Obesity; Phenylalanine; Postprandial Period | 2003 |
[Nateglinide and mitiglinide].
Topics: Cardiovascular Diseases; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hyperglycemia; Hypoglycemic Agents; Indoles; Insulin; Insulin Resistance; Insulin Secretion; Isoindoles; Metformin; Nateglinide; Phenylalanine; Postprandial Period; Stimulation, Chemical | 2003 |
[Pathophysiological conditions progressing from impaired glucose tolerance: coronary artery disease (ischemic heart disease)].
Topics: Acarbose; Cyclohexanes; Fasting; Glucose Intolerance; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Life Style; Myocardial Ischemia; Nateglinide; Phenylalanine; Pioglitazone; Postprandial Period; Protein Kinase C; Thiazolidinediones | 2005 |
[Effects of nateglinide in impaired glucose tolerance subjects].
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Cyclohexanes; Diabetes Mellitus, Type 2; Glucose Intolerance; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Nateglinide; Obesity; Phenylalanine; Postprandial Period; Risk Factors | 2005 |
[NAVIGATOR trial (nateglinide)].
Topics: Cardiovascular Diseases; Cyclohexanes; Diabetes Mellitus, Type 2; Endpoint Determination; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Life Style; Nateglinide; Phenylalanine; Primary Prevention; Randomized Controlled Trials as Topic; Risk | 2005 |
[Therapies for newly-onset diabetic patients].
Topics: Acarbose; Cyclohexanes; Diabetes Mellitus, Type 2; Diet Therapy; Enzyme Inhibitors; Exercise Therapy; Glucose; Glucose Intolerance; Glycogen; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Metformin; Nateglinide; Phenylalanine; Sulfonylurea Compounds; Thiazolidinediones | 2005 |
New drugs for diabetes.
Topics: Carbamates; Chromans; Cyclohexanes; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Nateglinide; Phenylalanine; Piperidines; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
12 trial(s) available for phenylalanine and Insulin Resistance
| Article | Year |
|---|---|
Metabolic effects of insulin in a human model of ketoacidosis combining exposure to lipopolysaccharide and insulin deficiency: a randomised, controlled, crossover study in individuals with type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Biopsy; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Glycogen Synthase; Humans; Inflammation; Insulin; Insulin Resistance; Lipopolysaccharides; Male; Muscle, Skeletal; Oxygen; Phenylalanine; Phosphorylation; Signal Transduction; Time Factors; Treatment Outcome; Young Adult | 2017 |
Effects of pioglitazone versus glimepiride exposure on hepatocellular fat content in type 2 diabetes.
Topics: Adiponectin; Blood Glucose; Body Mass Index; C-Reactive Protein; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Hepatocytes; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Lipolysis; Male; Middle Aged; Nateglinide; Phenylalanine; Pioglitazone; Sulfonylurea Compounds; Thiazolidinediones; Treatment Outcome | 2013 |
Comparison of effects of α-Glucosidase inhibitors and glinide drugs on endothelial dysfunction in diabetic patients with coronary artery disease.
Topics: 1-Deoxynojirimycin; Aged; Aged, 80 and over; Coronary Artery Disease; Cyclohexanes; Diabetic Angiopathies; Dyslipidemias; Endothelium, Vascular; Enzyme Inhibitors; Female; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Middle Aged; Nateglinide; Phenylalanine | 2014 |
Effects of acute and chronic attenuation of postprandial hyperglycemia on postglucose-load endothelial function in insulin resistant individuals: is stimulation of first phase insulin secretion beneficial for the endothelial function?
Topics: Blood Glucose; Case-Control Studies; Cyclohexanes; Endothelium; Female; Glucose; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Nateglinide; Phenylalanine; Postprandial Period; Risk Factors; Vasodilation | 2008 |
[A comparison of efficacy and tolerance of nateglinide and acarbose monotherapy in type 2 diabetes mellitus].
Topics: Acarbose; Adult; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Insulin Resistance; Male; Middle Aged; Nateglinide; Phenylalanine | 2009 |
Extremity hyperinsulinemia stimulates muscle protein synthesis in severely injured patients.
Topics: Adult; Algorithms; Amino Acids; Blood Glucose; Burns; Cell Membrane; Critical Illness; Female; Gas Chromatography-Mass Spectrometry; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Models, Biological; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Wounds and Injuries | 2004 |
Beta-cell function in mild type 2 diabetic patients: effects of 6-month glucose lowering with nateglinide.
Topics: Aged; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Male; Middle Aged; Models, Biological; Nateglinide; Phenylalanine; Placebos; Severity of Illness Index | 2005 |
Beneficial effects of nateglinide on insulin resistance in type 2 diabetes.
Topics: Blood Glucose; Body Mass Index; Cyclohexanes; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Middle Aged; Nateglinide; Phenylalanine; Postprandial Period | 2006 |
Postprandial interstitial insulin concentrations in type 2 diabetes relatives.
Topics: Adipose Tissue; Adult; Anthropometry; Biological Transport; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Lipolysis; Male; Microdialysis; Middle Aged; Nateglinide; Phenylalanine; Postprandial Period; Regional Blood Flow | 2006 |
Nateglinide with glibenclamide examination using the respiratory quotient (RQ).
Topics: Aged; Blood Glucose; Body Weight; Cyclohexanes; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Lipids; Male; Middle Aged; Nateglinide; Phenylalanine; Weight Gain | 2006 |
Treating hyperglycemia improves skeletal muscle protein metabolism in cancer patients after major surgery.
Topics: Abdominal Neoplasms; Amino Acids; Arginine; Blood Glucose; Cancer Care Facilities; Combined Modality Therapy; Critical Care; Cross-Over Studies; Energy Metabolism; Female; Glutamine; Humans; Hyperglycemia; Insulin; Insulin Resistance; Leucine; Middle Aged; Muscle Proteins; Muscle, Skeletal; Overweight; Parenteral Nutrition, Total; Phenylalanine; Postoperative Complications; Radiotherapy, Adjuvant | 2008 |
Impairment of early insulin response after glucose load, rather than insulin resistance, is responsible for postprandial hyperglycemia seen in obese type 2 diabetes: assessment using nateglinide, a new insulin secretagogue.
Topics: Adult; Cyclohexanes; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Nateglinide; Obesity; Phenylalanine; Postprandial Period | 2000 |
42 other study(ies) available for phenylalanine and Insulin Resistance
| Article | Year |
|---|---|
Phenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ.
Topics: Animals; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Resistance; Mice; Phenylalanine; Sirtuin 1 | 2022 |
Helical-Like Assembly of Nateglinide as Coating for Oral Delivery of Insulin and Their Synergistic Prevention of Diabetes Mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Humans; Insulin; Insulin Resistance; Mice; Microgels; Nateglinide; Phenylalanine | 2023 |
Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts.
Topics: Adult; Biomarkers; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Fatty Acids; Female; Finland; Humans; Incidence; Insulin; Insulin Resistance; Male; Middle Aged; Phenylalanine; Risk; Young Adult | 2019 |
Maternal BMI and Glycemia Impact the Fetal Metabolome.
Topics: 3-Hydroxybutyric Acid; Adiposity; Adult; Amino Acids, Branched-Chain; Birth Weight; Blood Glucose; Body Mass Index; Cohort Studies; Diabetes Mellitus, Type 2; Ethnicity; Female; Fetal Blood; Fetus; Glucose Tolerance Test; Humans; Infant, Newborn; Insulin Resistance; Linear Models; Male; Meta-Analysis as Topic; Metabolome; Metabolomics; Obesity; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Triglycerides; Young Adult | 2017 |
Specific plasma amino acid disturbances associated with metabolic syndrome.
Topics: Adult; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Anthropometry; Biomarkers; Humans; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Obesity; Phenylalanine; Reproducibility of Results | 2017 |
Carbohydrate status in patients with phenylketonuria.
Topics: Adolescent; Adult; Amino Acids; Biopterins; Body Mass Index; Carbohydrate Metabolism; Child; Child, Preschool; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Insulin Resistance; Male; Middle Aged; Multicenter Studies as Topic; Phenylalanine; Phenylketonurias; Postprandial Period; Young Adult | 2018 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Upper-body obese women are resistant to postprandial stimulation of protein synthesis.
Topics: Adult; Blood Glucose; Body Composition; Body Fat Distribution; Body Mass Index; Fatty Acids, Nonesterified; Female; Humans; Insulin; Insulin Resistance; Middle Aged; Obesity; Phenylalanine; Postprandial Period; Waist-Hip Ratio | 2014 |
High insulin combined with essential amino acids stimulates skeletal muscle mitochondrial protein synthesis while decreasing insulin sensitivity in healthy humans.
Topics: Adolescent; Adult; Amino Acids, Essential; Blood Glucose; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Mitochondria, Muscle; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Somatostatin; Young Adult | 2014 |
Age-Dependent Onset of Insulin Resistance in Insulin-Resistant Mice.
Topics: Adipose Tissue; Age Factors; Animals; Blood Glucose; Cyclohexanes; Glucose; Glucose Intolerance; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice, Inbred Strains; Nateglinide; Obesity; Phenylalanine; Receptor, Insulin; RNA, Messenger | 2015 |
Tryptophan Predicts the Risk for Future Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Isoleucine; Leucine; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Prognosis; Risk Factors; Tryptophan; Tyrosine; Valine | 2016 |
Urine metabolomics of high-fat diet induced obesity using UHPLC-Q-TOF-MS.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Diet, High-Fat; Gastrointestinal Microbiome; Glucose; Insulin Resistance; Male; Mass Spectrometry; Metabolomics; Multivariate Analysis; Obesity; Oxidative Stress; Phenylalanine; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Tryptophan; Urinalysis | 2017 |
Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice.
Topics: Alkaline Phosphatase; Animals; Aspartame; Biomarkers; Biotransformation; Blood Glucose; Diet, High-Fat; Enzyme Inhibitors; Glucose Intolerance; Insulin Resistance; Intestinal Mucosa; Intestine, Small; Male; Metabolic Syndrome; Mice, Inbred C57BL; Non-Nutritive Sweeteners; Obesity; Phenylalanine; Tumor Necrosis Factor-alpha; Weight Gain | 2017 |
Chromium (D-phenylalanine)3 supplementation alters glucose disposal, insulin signaling, and glucose transporter-4 membrane translocation in insulin-resistant mice.
Topics: Animal Feed; Animals; Biological Transport; Blood Glucose; Deoxyglucose; Dietary Supplements; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Mice; Muscle Proteins; Muscle, Skeletal; Organometallic Compounds; Phenylalanine; Protein Transport; Signal Transduction | 2008 |
A newly synthetic chromium complex-chromium (D-phenylalanine)3 activates AMP-activated protein kinase and stimulates glucose transport.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport, Active; Cell Line; Chromium Compounds; Enzyme Activation; Glucose; Insulin Resistance; Mice; Myocytes, Cardiac; Organometallic Compounds; Phenylalanine; Rats; Signal Transduction | 2009 |
Impaired muscle protein anabolic response to insulin and amino acids in heart failure patients: relationship with markers of immune activation.
Topics: Aged; Amino Acids; Anthropometry; Biomarkers; Fasting; Heart Failure; Humans; Insulin; Insulin Resistance; Interleukin-6; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Phenylalanine | 2010 |
Combination therapy with nateglinide and telmisartan ameliorates insulin resistance in zucker Fatty rats by suppressing advanced glycation end product receptor axis.
Topics: Animals; Benzimidazoles; Benzoates; Cyclohexanes; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Glycation End Products, Advanced; Humans; Insulin Resistance; Liver; Male; Nateglinide; Phenylalanine; Rats; Rats, Zucker; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Telmisartan | 2011 |
Chromium (D-phenylalanine)3 alleviates high fat-induced insulin resistance and lipid abnormalities.
Topics: Animals; Blood Glucose; Blotting, Western; Cell Line; Dietary Fats; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Organometallic Compounds; Phenylalanine; Random Allocation; Signal Transduction | 2011 |
Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine.
Topics: Adipokines; Adult; Aged; Calorimetry, Indirect; Case-Control Studies; Cysteine; Fatty Liver; Female; Glutathione; Homocysteine; Humans; Inflammation Mediators; Insulin Resistance; Liver; Male; Methionine; Methylation; Middle Aged; Non-alcoholic Fatty Liver Disease; Phenylalanine; Proteins; Urea; Young Adult | 2011 |
Preoperative insulin resistance and the impact of feeding on postoperative protein balance: a stable isotope study.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Blood Glucose; Cardiopulmonary Bypass; Eating; Energy Intake; Fasting; Female; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Phenylalanine; Postoperative Period; Proteins | 2011 |
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.
Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Glycine; Hexoses; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Metabolomics; Middle Aged; Phenylalanine; Phosphatidylcholines; Risk; Serum; Sphingomyelins | 2013 |
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
Topics: Adult; Amino Acids; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Phenylalanine; Tyrosine; Valine; Young Adult | 2013 |
[Dangerous postprandial glucose peaks. Risk for heart and blood vessels].
Topics: Cyclohexanes; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Metformin; Nateglinide; Phenylalanine; Postprandial Period | 2002 |
[Islands cells are not activated quickly enough. Risk of obstruction of blood vessels].
Topics: Arteriosclerosis; Blood Glucose; Cyclohexanes; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Islets of Langerhans; Metformin; Nateglinide; Phenylalanine; Postprandial Period; Risk | 2002 |
Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients.
Topics: Adult; Aged; Burns; Calorimetry, Indirect; Energy Metabolism; Humans; Hyperglycemia; Insulin Resistance; Middle Aged; Muscle Proteins; Phenylalanine; Retrospective Studies | 2002 |
Improvement of insulin resistance by a new insulin secretagogue, nateglinide--analysis based on the homeostasis model.
Topics: Aged; Blood Glucose; Body Mass Index; Cyclohexanes; Glycated Hemoglobin; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Kinetics; Middle Aged; Models, Biological; Nateglinide; Phenylalanine; Regression Analysis | 2003 |
[Achieving better control of blood sugar--understanding of oral hypoglycemic agents according to their characteristics in pharmacological action mechanism (discussion)].
Topics: Administration, Oral; Cardiovascular Diseases; Cyclohexanes; Diabetes Complications; Diabetes Mellitus; Drug Therapy, Combination; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Hypoglycemic Agents; Indoles; Inositol; Insulin; Insulin Resistance; Insulin Secretion; Isoindoles; Nateglinide; Phenylalanine; Risk Factors; Stimulation, Chemical; Sulfonylurea Compounds; Thiazolidinediones | 2004 |
Weight loss-associated changes in acute effects of nateglinide on insulin secretion after glucose loading: results of glucose loading on 2 consecutive days.
Topics: Adipose Tissue; Administration, Oral; Blood Glucose; C-Peptide; Cyclohexanes; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male; Middle Aged; Muscle, Skeletal; Nateglinide; Obesity; Phenylalanine; Weight Loss | 2005 |
Insulin resistance of muscle protein metabolism in aging.
Topics: Adult; Aged; Aging; Blood Flow Velocity; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Leg; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine | 2006 |
Insulin-sensitizing and cholesterol-lowering effects of chromium (D-Phenylalanine)3.
Topics: Animals; Anticholesteremic Agents; Blood Glucose; Blotting, Western; Body Weight; Cholesterol; Electrophoresis, Polyacrylamide Gel; Insulin Resistance; Lipid Peroxidation; Liver; Male; Mice; Organometallic Compounds; Phenylalanine; Phosphorylation; Proto-Oncogene Proteins c-akt | 2006 |
Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity.
Topics: Animals; Biopsy; Carbon Isotopes; Cattle; Cell Membrane; Dietary Proteins; Energy Metabolism; Fatty Acids, Omega-3; Fish Oils; Glucose Clamp Technique; Growth; Hyperinsulinism; Insulin; Insulin Resistance; Muscle, Skeletal; Phenylalanine; Phospholipids; Protein Kinases; Proto-Oncogene Proteins c-akt; Regression Analysis; Ribosomal Protein S6 Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2007 |
Key role of insulin resistance in vascular injury among hemodialysis patients.
Topics: Aged; Blood Pressure; Carnitine; Cyclohexanes; Diabetic Nephropathies; Female; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Lipoprotein Lipase; Lipoproteins, LDL; Male; Middle Aged; Nateglinide; Phenylalanine; Regression Analysis; Renal Dialysis; Vascular Diseases | 2007 |
Hyperinsulinemia inhibits myocardial protein degradation in patients with cardiovascular disease and insulin resistance.
Topics: Amino Acids; Blood Glucose; Coronary Disease; Fatty Acids, Nonesterified; Glucose; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Male; Middle Aged; Muscle Proteins; Myocardium; Phenylalanine | 1995 |
Leucine and phenylalanine kinetics in compensated liver cirrhosis: effects of insulin.
Topics: Adult; Humans; Insulin; Insulin Resistance; Leucine; Liver Cirrhosis; Male; Middle Aged; Phenylalanine | 1993 |
Actions of the novel oral antidiabetic agent HQL-975 in insulin-resistant non-insulin-dependent diabetes mellitus model animals.
Topics: Administration, Oral; Animals; Deoxyglucose; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Mice; Mice, Inbred Strains; Oxazoles; Phenylalanine; Rats; Rats, Inbred Strains; Rats, Wistar | 1998 |
The effect of the new oral hypoglycemic agent A-4166 on glucose turnover in the high fat diet-induced and/or in the hereditary insulin resistance of rats.
Topics: Animals; Body Weight; Cyclohexanes; Deoxyglucose; Dietary Fats; Glucose; Glucose Clamp Technique; Hypoglycemic Agents; Insulin Resistance; Male; Nateglinide; Phenylalanine; Phosphorylation; Rats; Rats, Wistar | 1998 |
Effects of new hypoglycemic agent A-4166 on lipolysis and lipogenesis in rat adipocytes.
Topics: Adipocytes; Animals; Blood Glucose; Cyclohexanes; Fatty Acids, Nonesterified; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Lipolysis; Male; Nateglinide; Norepinephrine; Phenylalanine; Rats; Rats, Wistar | 2000 |
Early insulin release effectively improves glucose tolerance: studies in two rodent models of type 2 diabetes mellitus.
Topics: Animals; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Type 2; Dietary Fats; Gastric Emptying; Glipizide; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Nateglinide; Phenylalanine; Rats; Rats, Sprague-Dawley; Rats, Zucker | 2001 |
Post-load hyperglycaemia-an inappropriate therapeutic target.
Topics: Blood Glucose; Cardiovascular Diseases; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Nateglinide; Patient Selection; Phenylalanine; Postprandial Period; Practice Guidelines as Topic; Predictive Value of Tests | 2002 |
Induction of insulin resistance in primary cultured adult cardiac myocytes.
Topics: Animals; Biological Transport; Bucladesine; Cells, Cultured; Cyclic AMP; Cycloheximide; Cytochalasin B; Deoxyglucose; Fatty Acids; Heart; Insulin; Insulin Resistance; Isoproterenol; Male; Myocardium; Nifedipine; Phenylalanine; Phosphorylation; Rats; Rats, Inbred Strains | 1991 |
Levonorgestrel and norethindrone alter insulin action on skeletal muscle of the female rat.
Topics: Animals; Contraceptive Agents, Female; Dose-Response Relationship, Drug; Female; Glucose; Hindlimb; Insulin; Insulin Antagonists; Insulin Resistance; Levonorgestrel; Muscles; Norethindrone; Norgestrel; Phenylalanine; Progesterone Congeners; Rats; Rats, Inbred Strains | 1990 |
Plasma amino acid levels and insulin secretion in obesity.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine | 1969 |