phenylalanine has been researched along with Inflammation in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (9.38) | 18.7374 |
| 1990's | 3 (4.69) | 18.2507 |
| 2000's | 11 (17.19) | 29.6817 |
| 2010's | 27 (42.19) | 24.3611 |
| 2020's | 17 (26.56) | 2.80 |
| Authors | Studies |
|---|---|
| Castro, A; Cominetti, MR; de Freitas Anibal, F; Di Medeiros Leal, MCB; Ferreira, AG; Luporini, RL; Pott-Junior, H | 1 |
| Ebrahim-Habibi, A; Navidpour, L; Saadati-Eskandari, N; Yaghmaei, P | 1 |
| Capuron, L; Castanon, N; Cussotto, S; Fanet, H; Monchaux De Oliveira, C; Vancassel, S | 1 |
| Chidangil, S; Devasia, T; John, RV; Lukose, J; N, M | 1 |
| Aala, WJ; Chen, YF; Chen, YL; Hou, PC; Hsu, CK; Lin, YC; Lu, HC; McGrath, JA; Onoufriadis, A | 1 |
| Joung, YS; Roh, S; Ryu, Y | 1 |
| Dou, X; Feng, C; Wang, X; Wu, B; Zhang, Y; Zhao, C | 1 |
| Borcherding, N; Cady, N; Jensen, SN; Mangalam, AK; Shrode, RL | 1 |
| Ai, X; Bao, WM; Dang, FT; Feng, J; Fu, HY; Gupta, AK; Ma, HT; Manandhar, LK; Tan, X; Tang, YM; Tu, RF; Xu, JM; Yang, WX; Yu, HY | 1 |
| Li, R; Li, Y; Liu, J; Meng, T; Qi, X; Qu, H; Tang, Y; Tao, Z; Wang, X; Xu, J; Yu, Y; Zhang, L; Zhou, M | 1 |
| Bruckner, T; Deisenhammer, EA; Egeter, J; Galffy, M; Giesinger, JM; Gostner, JM; Holzner, B; Hüfner, K; Lehmann, J; Nelles, P; Oberhammer, M; Rockenschaub, J; Sacher, M; Sperner-Unterweger, B; Tymoszuk, P; Vedova, S | 1 |
| Gao, J; Li, Y; Song, J; Wu, K; Xu, H; Yang, Y; Zhang, Y; Zhao, M; Zheng, Y; Zhou, L | 1 |
| Huang, L; Huang, T; Li, Z; Lin, R; Wang, X; Wu, P; Wu, Y | 1 |
| Friedenberg, FK; Piech, G; Reichenbach, ZW; Selby, A | 1 |
| Li, Z; Michel, F; Patin, E; Pellegrini, S; Rotival, M | 1 |
| Lin, MC; Neri, P; Perez, VL; Periman, LM; Saban, DR | 1 |
| Ishfaq, M; Li, J; Wang, J | 1 |
| Liu, S; Liu, Z; Pi, Z; Song, F; Wang, A; Zheng, Z | 1 |
| Jessen, N; Kampmann, U; Møller, N; Rittig, N; Svart, MV; Voss, TS | 1 |
| Gershon, MD; Gluck, K; Gross Margolis, K; Israelyan, N; Iuga, A; Li, Z; Saurman, V; Stevanovic, K; Talavera, M; Vittorio, J; Welch, MG | 1 |
| Bailey, DM; Berg, RMG; Dahl, RH; Larsen, FS; Lundby, C; Møller, K; Taudorf, S | 1 |
| Altun, B; Dmochowski, IJ; Greineder, CF; Khoshnejad, M; Muzykantov, VR; Pan, DC; Pulsipher, KW; Tsourkas, A; Villa, CH | 1 |
| Arvan, P; Haataja, L; Kim, GH; Long, Q; Low, MJ; Myers, MG; Nillni, EA; Qi, L; Shi, G; Somlo, DR; Song, S | 1 |
| de Paiva, CS; Guimaraes de Souza, R; Pflugfelder, SC; Stern, ME; Yu, Z | 1 |
| Engelmann, A; Guglielmo, K; Kiani, MF; Kilpatrick, LE; Kunapuli, S; Langston, J; Liverani, E; Patel, A; Soroush, F; Sun, S; Tang, Y | 1 |
| Guan, G; Huang, B; Ji, P; Li, J; Liao, P; Liu, H; Tan, B; Wang, J; Yin, Y | 1 |
| Bao, A; Gao, W; Li, Q; Lu, HY; Sun, L; Turvey, SE; Wang, K; Wang, L; Wang, Y; Xiong, Y; Yang, H | 1 |
| An, D; Cao, K; Chen, X; Li, N; Lu, Y; Wang, L; Wang, S; Wei, J; Yao, N; Zhao, D; Zhou, J | 1 |
| Blauth, M; Fuchs, D; Hüfner, K; Sperner-Unterweger, B | 1 |
| Bihani, G; Bodhankar, S; Dhaneshwar, S; Kusurkar, M | 1 |
| Copple, BL; Fickert, P; Jaeschke, H; Ramachandran, A; Trauner, M; Woolbright, BL; Yan, HM; Yang, M | 1 |
| Andrade, LN; de Cássia da Silveira E Sá, R; de Sousa, DP; Dos Reis Barreto de Oliveira, R | 1 |
| Bilic, J; Blaschitz, A; Desoye, G; Gauster, M; Huppertz, B; Kremshofer, J; Siwetz, M | 1 |
| Bach, E; Jessen, N; Johannsen, M; Jørgensen, JO; Møller, N; Richelsen, B; Rittig, N; Thomsen, HH | 1 |
| Acuña, MA; Benke, D; Burgos, CF; Corringer, PJ; Di Lio, A; Lara, CO; Moraga-Cid, G; Muñoz, B; Ralvenius, WT; Yévenes, GE; Zeilhofer, HU | 1 |
| Bechshoeft, R; Dideriksen, K; Holm, L; Malmgaard-Clausen, NM; Mikkelsen, UR; Petersen, RK; Reitelseder, S | 1 |
| Mátis, G; Neogrády, Z; Pászti-Gere, E; Pomothy, J; Rokonál, P; Steinmetzer, T; Szombath, G | 1 |
| Borzì, RM; Fini, M; Giavaresi, G; Grigolo, B; Maglio, M; Olivotto, E; Politi, L; Scandurra, R; Scotto d'Abusco, A; Veronesi, F | 1 |
| Paton, DM | 1 |
| Gui, L; Peng, S; Wang, Y; Wu, J; Zhang, X; Zhao, M; Zhao, S; Zhu, H | 1 |
| Fuchs, D; Ledochowski, M; Neurauter, G; Scholl-Bürgi, S; Schröcksnadel, K; Schubert, C; Sperner-Unterweger, B | 1 |
| Bhatnagar, S; Kumar, A | 1 |
| Ashwell, JD; Giardino Torchia, ML; Jirmanova, L; Mittelstadt, PR; Sarma, ND | 1 |
| Dürr, C; Follo, M; Idzko, M; Reichardt, W; Zeiser, R | 1 |
| Gadek, TR; O'Neill, CA; Pearlman, E; Sun, Y; Zhang, R | 1 |
| Besson, JM; Buritova, J; Catheline, G; Fournié-Zaluski, MC; Le Guen, S; Roques, BP | 1 |
| Besson, JM; Buritova, J; Fournié-Zaluski, MC; Le Guen, S; Roques, BP | 1 |
| Hellwig, D; Kirsch, CM; Menger, MD; Menges, M; Moellers, MO; Romeike, BF; Samnick, S; Schneider, G | 1 |
| Breyer, RM; Hata, AN; Lybrand, TP | 1 |
| Bacher, K; Cornelissen, B; De Spiegeleer, B; Dierckx, RA; Kersemans, K; Kersemans, V; Mertens, J; Slegers, G; Thierens, H | 1 |
| Aloisi, F; Cappelli, V; De Cian, F; Di Martino, M; Gandolfo, MT; Garibotto, G; Procopio, V; Sala, MR; Sofia, A; Tarroni, A; Verzola, D; Villaggio, B | 1 |
| Foda, H; Hymowitz, M; Montana, S; Rollo, EE; Schmidt, CE; Zucker, S | 1 |
| Butkevich, IP; Makukhina, GV; Mikhaĭlenko, VA | 1 |
| Arrastia, CD; Casperson, SL; Dillon, EL; Paddon-Jones, D; Sanford, AP; Sheffield-Moore, M; Sinha, S; Urban, RJ; Volpi, E; Wolfe, RR | 1 |
| Hiroi, T; Kaminuma, O; Kitamura, F; Kunori, Y; Mori, A; Nagakubo, D; Ogawa, K; Someya, K; Yoshie, O | 1 |
| Fournié-Zaluski, MC; Maldonado, R; Roques, BP; Turcaud, S; Valverde, O | 1 |
| Crimmin, MJ; DiMartino, MJ; Galloway, WA; High, W | 1 |
| Pass, MA; Pollitt, CC; Pollitt, S | 1 |
| Davis, RH | 1 |
| Dannenberg, AM; Harada, S; Higuchi, K; Kajiki, A; Nakamura, M; Pula, PJ; Scott, AL | 1 |
| Janoff, A; Klassen, A; Troll, W | 1 |
| Thomas, G; West, GB | 1 |
| Appel, W; Hermann, H; Huth, E | 1 |
| Davis, RH; Fisher, JS; McGowan, L | 1 |
4 review(s) available for phenylalanine and Inflammation
| Article | Year |
|---|---|
Pathophysiology, Differential Diagnosis, and Treatment of Diabetic Diarrhea.
Topics: Antidiarrheals; Autonomic Nervous System Diseases; Blind Loop Syndrome; Celiac Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Diarrhea; Diphenoxylate; Enteric Nervous System; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Inflammation; Inflammatory Bowel Diseases; Interstitial Cells of Cajal; Intestinal Absorption; Intestinal Mucosa; Irritable Bowel Syndrome; Loperamide; Neuroglia; Non-Nutritive Sweeteners; Oxidative Stress; Phenylalanine; Serotonin 5-HT3 Receptor Antagonists | 2019 |
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Topics: Administration, Topical; Clinical Decision-Making; Cyclosporine; Dry Eye Syndromes; Goblet Cells; Homeostasis; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammation; Integrins; Intercellular Adhesion Molecule-1; Lacrimal Apparatus; Lymphocyte Function-Associated Antigen-1; Phenylalanine; Steroids; Sulfones; T-Lymphocytes; Tears | 2020 |
A review on anti-inflammatory activity of phenylpropanoids found in essential oils.
Topics: Anti-Inflammatory Agents; Asthma; Biological Products; Cinnamates; Cytokines; Humans; Hypersensitivity; Immunomodulation; Inflammation; Oils, Volatile; Phenylalanine; Plants, Medicinal | 2014 |
Chronic immune stimulation correlates with reduced phenylalanine turnover.
Topics: Animals; Biogenic Monoamines; Biopterins; Homocysteine; Humans; Immune System; Inflammation; Interferon-gamma; Oxidative Stress; Phenylalanine | 2008 |
4 trial(s) available for phenylalanine and Inflammation
| Article | Year |
|---|---|
Baicalin ameliorates
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteroides fragilis; Chickens; Cytokines; Dysbiosis; Flavonoids; Gastrointestinal Microbiome; Inflammation; Lung; Macrophages; Mycoplasma gallisepticum; Mycoplasma Infections; Necroptosis; Necrosis; Phenylalanine; Poultry Diseases | 2021 |
Metabolic effects of insulin in a human model of ketoacidosis combining exposure to lipopolysaccharide and insulin deficiency: a randomised, controlled, crossover study in individuals with type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Biopsy; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Glycogen Synthase; Humans; Inflammation; Insulin; Insulin Resistance; Lipopolysaccharides; Male; Muscle, Skeletal; Oxygen; Phenylalanine; Phosphorylation; Signal Transduction; Time Factors; Treatment Outcome; Young Adult | 2017 |
Amino acid supplementation is anabolic during the acute phase of endotoxin-induced inflammation: A human randomized crossover trial.
Topics: Adaptor Proteins, Signal Transducing; Adult; Amino Acids; Body Mass Index; Cell Cycle Proteins; Cross-Over Studies; Dietary Supplements; Endotoxemia; Endotoxins; Glucose Clamp Technique; Hormones; Humans; Inflammation; Insulin; Interleukin-10; Interleukin-6; Linear Models; Male; Mechanistic Target of Rapamycin Complex 1; Models, Theoretical; Multiprotein Complexes; Muscle, Skeletal; Phenylalanine; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tyrosine; Urea | 2016 |
No effect of anti-inflammatory medication on postprandial and postexercise muscle protein synthesis in elderly men with slightly elevated systemic inflammation.
Topics: Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Composition; C-Reactive Protein; Cross-Sectional Studies; Denmark; Double-Blind Method; Humans; Ibuprofen; Inflammation; Insulin; Interleukin-6; Leucine; Linear Models; Male; Muscle Proteins; Myofibrils; Phenylalanine; Postprandial Period; Rats; Resistance Training; Ribosomal Protein S6 Kinases, 70-kDa | 2016 |
56 other study(ies) available for phenylalanine and Inflammation
| Article | Year |
|---|---|
Phenylalanine and COVID-19: Tracking disease severity markers.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Comorbidity; COVID-19; Cross-Sectional Studies; Cytokines; Female; Humans; Inflammation; Linear Models; Male; Middle Aged; Phenylalanine; Severity of Illness Index; Young Adult | 2021 |
Phenylalanine and indole effects on the pathogenicity of human lysozyme amorphous aggregates.
Topics: Animals; Cytokines; Glucose; Humans; Indoles; Inflammation; Liver; Male; Muramidase; Phenylalanine; Rats; Rats, Wistar; Virulence | 2022 |
Tetrahydrobiopterin modulates the behavioral neuroinflammatory response to an LPS challenge in mice.
Topics: Animals; Biopterins; Cytokines; Inflammation; Lipopolysaccharides; Mice; Phenylalanine; Tyrosine | 2022 |
Micro-Raman spectroscopy study of blood samples from myocardial infarction patients.
Topics: Humans; Inflammation; Myocardial Infarction; Phenylalanine; Spectrum Analysis, Raman; Tyrosine | 2022 |
Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa.
Topics: Chromatography, Liquid; Epidermolysis Bullosa Dystrophica; Fibrosis; Glutamates; Glutamine; Humans; Inflammation; Kynurenine; Malnutrition; Phenylalanine; Succinates; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
The effect of PhIP precursors on the generation of particulate matter in cooking oil fumes at high cooking temperatures and the inflammation response in human lung cells.
Topics: Amines; Carbon; Carcinogens; Cooking; Creatinine; Glucose; Humans; Inflammation; Interleukin-6; Lung; Meat; Particulate Matter; Phenylalanine; Polycyclic Aromatic Hydrocarbons; Smoke; Soybean Oil; Temperature | 2023 |
Polydopamine-doped supramolecular chiral hydrogels for postoperative tumor recurrence inhibition and simultaneously enhanced wound repair.
Topics: Antineoplastic Agents; Doxorubicin; Humans; Hydrogels; Hyperthermia, Induced; Inflammation; Neoplasm Recurrence, Local; Phenylalanine; Tumor Microenvironment; Wound Healing | 2022 |
Isoflavone consumption reduces inflammation through modulation of phenylalanine and lipid metabolism.
Topics: Animals; Arachidonic Acids; Bacteria; Equol; Estrogens; Fatty Acids, Monounsaturated; Glycerophospholipids; Inflammation; Isoflavones; Lipid Metabolism; Metabolomics; Mice; Phenylalanine; Phytoestrogens; Receptors, Estrogen; Sphingolipids | 2022 |
The
Topics: Animals; Clostridium; Inflammation; Kupffer Cells; Lipopolysaccharides; Liver Cirrhosis, Biliary; Mice; Phenylalanine; Sulfates; Tyrosine | 2022 |
Phenylalanine promotes alveolar macrophage pyroptosis
Topics: Animals; Inflammation; Macrophages, Alveolar; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylalanine; Pneumonia; Pyroptosis; Receptors, Calcium-Sensing; Respiratory Distress Syndrome | 2023 |
The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites.
Topics: COVID-19; Cross-Sectional Studies; Dopamine; Humans; Inflammation; Kynurenine; Mental Health; Phenylalanine; SARS-CoV-2; Serotonin; Tryptophan; Tyrosine | 2023 |
Bergamot polysaccharides relieve DSS-induced ulcerative colitis via regulating the gut microbiota and metabolites.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Mice; Mice, Inbred C57BL; Phenylalanine; Polysaccharides | 2023 |
Mechanism of the Effect of Compound
Topics: Animals; Chromatography, High Pressure Liquid; Inflammation; Liver; Metabolomics; Phenylalanine; Rats; Rats, Sprague-Dawley | 2023 |
Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage.
Topics: Alleles; Amino Acid Substitution; Autoimmune Diseases; B-Lymphocytes; Cytokines; Gene Expression Regulation; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Inflammation; Phenylalanine; Polymorphism, Single Nucleotide; Quantitative Trait Loci; TYK2 Kinase | 2020 |
Mass spectrometry-based urinary metabolomics for exploring the treatment effects of Radix ginseng-Schisandra chinensis herb pair on Alzheimer's disease in rats.
Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Inflammation; Mass Spectrometry; Medicine, Chinese Traditional; Metabolomics; Nervous System; Panax; Phenylalanine; Plant Extracts; Rats; Reproducibility of Results; Schisandra; Tandem Mass Spectrometry; Tyrosine; Urinalysis | 2021 |
Enteric serotonin and oxytocin: endogenous regulation of severity in a murine model of necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterochromaffin Cells; Enterocolitis, Necrotizing; Enzyme Inhibitors; Inflammation; Intestinal Mucosa; Liver; Mice; Oxytocin; Phenylalanine; Pyrimidines; Serotonin; Serotonin Plasma Membrane Transport Proteins; Severity of Illness Index; Signal Transduction; Tryptophan Hydroxylase | 2017 |
A reassessment of the blood-brain barrier transport of large neutral amino acids during acute systemic inflammation in humans.
Topics: Adult; Amino Acids, Neutral; Blood Flow Velocity; Blood-Brain Barrier; Capillary Permeability; Cerebrovascular Circulation; Humans; Inflammation; Infusions, Intravenous; Lipopolysaccharides; Male; Models, Biological; Phenylalanine; Sepsis; Tyrosine; Young Adult | 2018 |
Ferritin Nanocages with Biologically Orthogonal Conjugation for Vascular Targeting and Imaging.
Topics: Alkynes; Animals; Azides; Click Chemistry; Ferritins; Fluorescent Dyes; Humans; Immunoconjugates; Inflammation; Intercellular Adhesion Molecule-1; Lung; Mice; Nanostructures; Optical Imaging; Phenylalanine | 2018 |
Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
Topics: Animals; Axons; Cysteine; Endoplasmic Reticulum; Endoplasmic Reticulum-Associated Degradation; Feeding Behavior; Female; Green Fluorescent Proteins; Humans; Hypothalamus; Inflammation; Intracellular Signaling Peptides and Proteins; Leptin; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Obesity; Phenylalanine; Pro-Opiomelanocortin; Proteins; Sulfhydryl Compounds; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast.
Topics: Animals; Chemokine CXCL11; Chemokine CXCL9; Dry Eye Syndromes; Female; Inflammation; Interferon-gamma; Keratoconjunctivitis Sicca; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Phenylalanine; Sulfones; Th1 Cells | 2018 |
Protein Kinase C-Delta (PKCδ) Tyrosine Phosphorylation is a Critical Regulator of Neutrophil-Endothelial Cell Interaction in Inflammation.
Topics: Animals; Apoptosis; Bone Marrow Cells; Cell Adhesion; Endothelial Cells; Endothelium, Vascular; Female; Fibronectins; Gene Knock-In Techniques; Inflammation; Male; Mice; Mice, Transgenic; Microcirculation; Microfluidics; Neutrophil Activation; Neutrophils; Oxygen; Permeability; Peroxidase; Phenylalanine; Phosphorylation; Protein Kinase C-delta; Sepsis; Superoxides; Tyrosine | 2019 |
Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation.
Topics: Amino Acids, Aromatic; Animals; Colon; Cytokines; Diet; Dietary Supplements; Epithelial Cells; Female; I-kappa B Kinase; Inflammation; Intestines; Jejunum; Lipopolysaccharides; NF-kappa B; Peroxidase; Phenylalanine; Phosphorylation; Random Allocation; Receptors, Calcium-Sensing; RNA, Messenger; Signal Transduction; Sus scrofa; Swine; Tryptophan; Tumor Necrosis Factor-alpha; Tyrosine | 2018 |
Size-dependent anti-inflammatory activity of a peptide-gold nanoparticle hybrid in vitro and in a mouse model of acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Gold; Inflammation; Lipopolysaccharides; Metal Nanoparticles; Particle Size; Peptides; Phenylalanine | 2019 |
Fructus Gardeniae-induced gastrointestinal injury was associated with the inflammatory response mediated by the disturbance of vitamin B6, phenylalanine, arachidonic acid, taurine and hypotaurine metabolism.
Topics: Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Gardenia; Gastrointestinal Diseases; Inflammation; Male; Mass Spectrometry; Medicine, Chinese Traditional; Metabolomics; Mice; Phenylalanine; Plant Extracts; Taurine; Vitamin B 6 | 2019 |
How acute and chronic physical disease may influence mental health - An Analysis of neurotransmitter precursor amino acid levels.
Topics: Acute Disease; Adult; Aged; Amino Acids; Anxiety Disorders; C-Reactive Protein; Chronic Disease; Depression; Depressive Disorder; Female; Humans; Inflammation; Kynurenine; Male; Mental Disorders; Mental Health; Middle Aged; Neurotransmitter Agents; Phenylalanine; Prospective Studies; Tryptophan; Tyrosine | 2019 |
Carrier-linked mutual prodrugs of biphenylacetic acid as a promising alternative to bioprecursor fenbufen: design, kinetics, and pharmacological studies.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Drug Liberation; Female; Glycine; Humans; Inflammation; Male; Pain; Phenylacetates; Phenylalanine; Phenylbutyrates; Prodrugs; Rats; Rats, Wistar | 2014 |
Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.
Topics: Alanine Transaminase; Animals; Bile Acids and Salts; Bile Ducts; Cholestasis; Inflammation; Ligation; Male; Matrix Metalloproteinase 3; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Osteopontin; Phenylalanine; Thiophenes | 2014 |
Metalloprotease dependent release of placenta derived fractalkine.
Topics: Adult; Cell Line; Cell Membrane; Chemokine CX3CL1; Female; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Inflammation; Metalloproteases; Microvilli; Phenylalanine; Placenta; Pregnancy; Pregnancy Trimester, First; Thiophenes; Trophoblasts | 2014 |
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain.
Topics: Allosteric Site; Animals; Female; HEK293 Cells; Humans; Hyperalgesia; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Neurons; Pain; Pain Management; Phenols; Phenylalanine; Phosphorylation; Protein Conformation; Receptors, Glycine; Recombinant Proteins; Spinal Cord | 2016 |
The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models.
Topics: Animals; Cell Death; Hepatocytes; Hepcidins; Hydrogen Peroxide; Inflammation; Interleukin-6; Interleukin-8; Kupffer Cells; Liver; Liver Diseases; Male; Oxidative Stress; Phenylalanine; Reactive Oxygen Species; Serine Endopeptidases; Swine | 2016 |
Chondroprotective activity of N-acetyl phenylalanine glucosamine derivative on knee joint structure and inflammation in a murine model of osteoarthritis.
Topics: ADAMTS5 Protein; Animals; Cartilage, Articular; Disease Models, Animal; Glucosamine; I-kappa B Kinase; Inflammation; Injections, Intra-Articular; Knee Joint; Male; Matrix Metalloproteinase 10; Matrix Metalloproteinase 13; Menisci, Tibial; Mice; Organ Size; Osteoarthritis, Knee; Phenylalanine | 2017 |
Lifitegrast: First LFA-1/ICAM-1 antagonist for treatment of dry eye disease.
Topics: Anti-Inflammatory Agents; Clinical Studies as Topic; Drug Evaluation, Preclinical; Dry Eye Syndromes; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Ophthalmic Solutions; Phenylalanine; Sulfones; T-Lymphocytes | 2016 |
Topics: Animals; Antineoplastic Agents; Carbolines; Cell Line, Tumor; Cell Proliferation; DNA; DNA Cleavage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Molecular Structure; Nanoparticles; Neoplasms, Experimental; Phenylalanine; Structure-Activity Relationship; Thrombosis | 2017 |
Matrix metalloproteinase inhibitor batimastat alleviates pathology and improves skeletal muscle function in dystrophin-deficient mdx mice.
Topics: Animals; Disease Models, Animal; Dystrophin; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Phenylalanine; Protease Inhibitors; Thiophenes; Transcription Factor AP-1 | 2010 |
Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation.
Topics: Animals; Arthritis, Experimental; Autoimmunity; Blotting, Western; Cell Cycle Proteins; Cell Proliferation; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Female; Gene Knock-In Techniques; Inflammation; Lymphocyte Activation; Mice; Mice, Transgenic; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phosphorylation; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tyrosine | 2011 |
Graft-versus-host disease reduces regulatory T-cell migration into the tumour tissue.
Topics: Animals; Cell Movement; Cells, Cultured; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Inflammation; Intestines; Lymphoma, B-Cell; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Naphthalenes; Phenylalanine; Receptors, CCR3; Receptors, Purinergic P2Y2; Signal Transduction; T-Lymphocytes, Regulatory; Transplantation, Homologous; Tumor Microenvironment | 2012 |
Corneal inflammation is inhibited by the LFA-1 antagonist, lifitegrast (SAR 1118).
Topics: Animals; CD11a Antigen; CD18 Antigens; Contact Lenses; Cornea; Corneal Stroma; Disease Models, Animal; Eye Infections, Bacterial; Inflammation; Lymphocyte Function-Associated Antigen-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neutrophil Infiltration; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus aureus; Sulfones | 2013 |
Further evidence for the interaction of mu- and delta-opioid receptors in the antinociceptive effects of the dual inhibitor of enkephalin catabolism, RB101(S). A spinal c-Fos protein study in the rat under carrageenin inflammation.
Topics: Analgesics; Animals; Carrageenan; Disulfides; Edema; Enkephalins; Gene Expression Regulation; Inflammation; Male; Phenylalanine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 2003 |
Antinociceptive effects of RB101(S), a complete inhibitor of enkephalin-catabolizing enzymes, are enhanced by (+)-HA966, a functional NMDA receptor antagonist: a c-Fos study in the rat spinal cord.
Topics: Analgesics; Animals; Carrageenan; Disulfides; Drug Therapy, Combination; Enkephalins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Immunohistochemistry; Inflammation; Male; Naloxone; Narcotic Antagonists; Pain; Phenylalanine; Proto-Oncogene Proteins c-fos; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2003 |
Radioiodinated phenylalanine derivatives to image pancreatic cancer: a comparative study with [18F]fluoro-2-deoxy-D-glucose in human pancreatic carcinoma xenografts and in inflammation models.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Disease Models, Animal; Fluorodeoxyglucose F18; Humans; Inflammation; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Transplantation, Heterologous | 2005 |
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamic Acid; Humans; Hypersensitivity; Indomethacin; Inflammation; Kinetics; Ligands; Mice; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Tyrosine | 2005 |
In vivo evaluation and dosimetry of 123I-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT, in an R1M rhabdomyosarcoma athymic mouse model.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Cluster Analysis; Disease Models, Animal; Evaluation Studies as Topic; Humans; Image Processing, Computer-Assisted; Inflammation; Iodine Radioisotopes; Kinetics; Male; Mice; Mice, Nude; Phenylalanine; Radiation Dosage; Radiometry; Radionuclide Imaging; Radiopharmaceuticals; Rhabdomyosarcoma; Time Factors; Tomography, Emission-Computed, Single-Photon | 2005 |
Peripheral tissue release of interleukin-6 in patients with chronic kidney diseases: effects of end-stage renal disease and microinflammatory state.
Topics: Aged; Arteries; Biopsy; Cardiovascular Diseases; Female; Forearm; Gene Expression; Humans; Immunohistochemistry; Inflammation; Interleukin-1; Interleukin-10; Interleukin-6; Male; Middle Aged; Muscle, Skeletal; Phenylalanine; Renal Insufficiency, Chronic; RNA, Messenger; Tumor Necrosis Factor-alpha; Uremia; Veins | 2006 |
Neutrophil activator of matrix metalloproteinase-2 (NAM).
Topics: Adult; Amides; Calcimycin; Cathepsin G; Cathepsins; Cells, Cultured; Culture Media, Conditioned; Endothelium, Vascular; Enzyme Activation; Enzyme Precursors; Humans; Inflammation; Ionomycin; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Neoplasm Metastasis; Neutrophils; Oligopeptides; Pancreatic Elastase; Phenylalanine; Protease Inhibitors; Proteins; RNA, Messenger; Serine Endopeptidases; Substrate Specificity; Tetradecanoylphorbol Acetate; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Umbilical Veins | 2006 |
[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress].
Topics: Aging; Analgesics; Animals; Female; Inflammation; Male; Ondansetron; Pain; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Stress, Physiological | 2007 |
Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy.
Topics: Amino Acids; Blood Chemical Analysis; Cytokines; Deuterium; Female; Humans; Inflammation; Middle Aged; Muscle Proteins; NF-kappa B; Ovarian Neoplasms; Phenylalanine | 2007 |
Selective suppression of Th2-mediated airway eosinophil infiltration by low-molecular weight CCR3 antagonists.
Topics: Animals; Benzamides; Bronchial Hyperreactivity; Chemotaxis, Leukocyte; Eosinophils; Inflammation; Lung; Mice; Naphthalenes; Neutrophils; Phenylalanine; Receptors, CCR3; Th1 Cells; Th2 Cells | 2007 |
Antinociceptive response induced by mixed inhibitors of enkephalin catabolism in peripheral inflammation.
Topics: Analgesics; Animals; Disulfides; Enkephalins; Hydroxamic Acids; Inflammation; Injections, Intraventricular; Male; Morphine; Naloxone; Narcotic Antagonists; Neprilysin; Pain; Pain Measurement; Phenylalanine; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley | 1994 |
Preclinical antiarthritic activity of matrix metalloproteinase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Indomethacin; Inflammation; Isomerism; Metalloendopeptidases; Phenylalanine; Radiography; Rats; Thiophenes; Time Factors | 1994 |
Batimastat (BB-94) inhibits matrix metalloproteinases of equine laminitis.
Topics: Animals; Culture Media; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Foot Diseases; Gelatinases; Hoof and Claw; Horse Diseases; Horses; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Phenylalanine; Protease Inhibitors; Thiophenes | 1998 |
Inhibition of inflammation with certain amino acids.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Edema; Hindlimb; Inflammation; Male; Phenylalanine; Rats; Tryptophan | 1978 |
Proteases released in organ culture by acute dermal inflammatory lesions produced in vivo in rabbit skin by sulfur mustard: hydrolysis of synthetic peptide substrates for trypsin-like and chymotrypsin-like enzymes.
Topics: Animals; Blood Proteins; Coumarins; Hydrolysis; Inflammation; Mustard Compounds; Mustard Gas; Oligopeptides; Organ Culture Techniques; Peptide Hydrolases; Phenylalanine; Rabbits; Skin; Substrate Specificity; Wound Healing | 1988 |
Local vascular changes induced by the cocarcinogen, phorbol myristate acetate.
Topics: Acetates; Animals; Benz(a)Anthracenes; Carcinogens; Ear; Edema; Female; Histamine H1 Antagonists; Hydrocortisone; Hyperemia; Inflammation; Ketones; Kinins; Mast Cells; Mice; Phenylalanine; Serotonin Antagonists; Serum Albumin, Radio-Iodinated; Skin; Skin Diseases | 1970 |
Amino acids and inflammation.
Topics: Amino Acids; Animals; Carrageenan; Cysteine; Dextrans; Dose-Response Relationship, Drug; Esters; Freund's Adjuvant; Glycine; Hindlimb; Inflammation; Penicillamine; Phenylalanine; Rats | 1973 |
[Serum carboxypeptidases in inflammatory illnesses].
Topics: Adolescent; Anilides; Bronchitis; Carboxypeptidases; Child; Child, Preschool; Colitis, Ulcerative; Diabetes Mellitus; Dipeptides; Gastroenteritis; Humans; Inflammation; Leucyl Aminopeptidase; Leukemia, Lymphoid; Leukemia, Myeloid; Phenylalanine; Pneumonia; Rheumatic Fever; Virus Diseases | 1969 |
Local antiphlogistic activity of L-phenylalanine and L-tryptophane.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Cortisone; Depression, Chemical; Gelatin; Inflammation; Leukocyte Count; Leukocytes; Male; Neutrophils; Phenylalanine; Rats; Stereoisomerism; Tryptophan | 1968 |