phenylalanine and Glioma

phenylalanine has been researched along with Glioma in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (6.90)	18.7374
1990's	16 (27.59)	18.2507
2000's	23 (39.66)	29.6817
2010's	11 (18.97)	24.3611
2020's	4 (6.90)	2.80

Authors

Authors	Studies
Aggarwal, N; Bera, C; Chauhan, VS; Chibh, S; Mallick, Z; Mandal, D; Panda, JJ; Sachdeva, PK; Sengupta, D; Yadav, N	1
Alhallak, K; Azab, AK; de la Puente, P; Federico, C; Guenthner, N; Luderer, MJ; Muz, B; Sun, J; Wasden, K	1
Chaboub, N; Devillers, A; Girard, A; Le Jeune, F; Le Reste, PJ; Metais, A; Palard-Novello, X; Saint-Jalmes, H	1
Bandyopadhyay, A; Goswami, A; Lamba, M	1
Dousti, F; Hassanzadeh, F; Kasesaz, Y; Mirian, M; Rostami, M; Soleimanbeigi, M; Varshosaz, J	1
Alves, WA; Hamley, IW; Han, SW; Listik, E; Reza, M; Ruokolainen, J; Silva, ER; Soares, BM	1
Aoki, M; Hatazawa, J; Horitsugi, G; Ikeda, H; Kanai, Y; Kongpracha, P; Nagamori, S; Naka, S; Shimosegawa, E; Watabe, T	1
Huang, C; McConathy, J; Rich, KM; Yuan, L	1
Barth, RF; Chandra, S; Haider, SA; Huo, T; Kabalka, GW; Shaikh, AL; Yang, W	1
Chang, CW; Chang, WY; Chen, JC; Li, JJ; Wang, HE; Yang, FY	1
Hao, E; Hiramatsu, R; Kawabata, S; Kuroiwa, T; Miyatake, S; Ono, K; Sakurai, Y; Suzuki, M; Tanaka, H; Vicente, MG	1
Bozzali, M; Cametti, C; Capuani, S; Colasanti, M; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Pastore, FS; Porcari, P; Russo, S; Venturini, G	1
Bozzali, M; Cametti, C; Capuani, S; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Muolo, M; Pastore, FS; Porcari, P; Russo, S	1
Campanella, R; Capuani, S; D'Amore, E; Fasano, F; La Bella, A; Lecce, M; Maraviglia, B; Migneco, LM; Pastore, FS; Porcari, P	1
Inaji, M; Ishii, K; Ishiwata, K; Kimura, Y; Matsumura, A; Momose, T; Nariai, T; Ohno, K; Yamamoto, T	1
Boddy, A; Braithwaite, R; Chester, M; Chopra, A; Croswell, G; Cruickshank, GS; Detta, A; Doran, J; Elliot, M; Ford, S; Ghani, Z; Graham, N; Green, S; Halbert, G; Hardie, J; James, ND; Lockyer, N; Ngoga, D; Sheehan, TM; Steinfeldt, H; Sugar, R; Vickerman, J; Wojnecki, C	1
Barth, RF	1
Barth, RF; Binns, P; Riley, K; Tjarks, W; Wu, G; Yang, W	1
Israel, I; Kirsch, CM; Lehmann, T; Mautes, A; Reiners, C; Romeike, BF; Rübe, C; Samnick, S	1
Grote, M; Knapp, WH; Korkmaz, Z; Krull, D; Meyer, GJ; Sriyapureddy, SR; Walte, A	1
Farmakis, G; Grgic, A; Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Steudel, WI	1
Kung, HF; Lieberman, BP; Plössl, K; Qu, W; Wang, L	1
Chen, G; Chen, J; Du, Z; Huang, Q; Li, B; Sun, T; Wei, Y; Xie, X; Zhou, Y	1
Imahori, Y; Mineura, K; Takahashi, Y	1
Chang, PF; Chen, FD; Chen, JC; Deng, WP; Hwang, JJ; Lee, JS; Liao, AH; Liu, RS; Wang, HE	1
Chang, SM; Chen, JC; Hsu, FY; Liu, RS; Wang, HE	1
Bandyopadhyaya, AK; Barth, RF; Binns, PJ; Ciesielski, MJ; Coderre, JA; Fenstermaker, RA; Patel, H; Riley, K; Thirumamagal, BT; Tjarks, W; Wu, G; Yang, W	1
Capala, J; Dahlström, M; Lindström, A; Lindström, P; Wasteson, A	1
Al-Madhoun, AS; Barth, RF; Byun, Y; Chandra, S; Eriksson, S; Johnsamuel, J; Smith, DR; Tjarks, W; Yang, W	1
Chang, CW; Chen, FD; Chen, JC; Chen, YF; Hsieh, CH; Hwang, JJ; Kai, JJ; Liu, RS; Wang, HE	1
Betti, M; Carlos, R; Cionini, L; de las Heras, LA; Lazzerini, G; Menichetti, L; Pitois, A; Salvatori, PA; Zampolli, A	1
Asano, T; Doi, A; Kajimoto, Y; Kawabata, S; Kirihata, M; Kuroiwa, T; Miyatake, S; Ono, K; Yokoyama, K; Yoshida, T	1
Asano, T; Hattori, Y; Kirihata, M; Kondoh, H; Kurihara, K; Wakamiya, T; Yamaguchi, Y	1
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S	1
Brandau, W; Farmakis, G; Hellwig, D; Kirsch, CM; Samnick, S; Schaefer, A; Wollenweber, F	1
Carlsson, J; Larsson, BS; Lindström, P; Olsson, P; Pettersson, OA; Sjöberg, S	1
Allen, BJ; Jones, R; Mallesch, JL; McCarthy, WH; Moore, DE; Stening, WA	1
Barth, RF; Coderre, JA; Matalka, KZ; Moeschberger, ML; Staubus, AE	1
Cai, J; Iwamoto, S; Kikuchi, H; Nemoto, H; Oda, Y; Ono, K; Takagaki, M; Yamamoto, Y	1
Barth, RF; Carpenter, DE; Goodman, JH; Moeschberger, ML; Yang, W	1
Hatazawa, J; Iida, H; Inugami, A; Kanno, I; Miura, S; Murakami, M; Ogawa, T; Sasajima, T; Uemura, K; Yasui, N	1
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Soloway, AH; Yang, W	1
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W	1
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S	1
Fujii, R; Ido, T; Imahori, Y; Kobayashi, T; Kusuki, T; Ohmori, Y; Ono, K; Sakae, K; Takagaki, M; Ueda, S	2
Barth, RF; Bartus, RT; Goodman, JH; Moeschberger, ML; Yang, W	1
Bouterfa, H; Hanke, A; Kerkau, S; Mueller, JG; Roosen, K; Tonn, JC; Vince, GH; Wagner, S	1
Barth, RF; Boesel, CP; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Ono, K; Rotaru, JH; Soloway, AH; Yang, W	1
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Goodman, JH; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W	1
Friedrich, M; Halfter, H; Kopka, K; Riemann, B; Ringelstein, EB; Schober, O; Stögbauer, F; Weckesser, M; Winters, S	1
Adelman, LS; Cano, G; Harling, OK; Joyce, MA; Kerley, SE; Madoc-Jones, H; Saris, SC; Solares, GR; Wazer, DE; Zamenhof, RG	1
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM; Slatkin, DN	1
Coderre, JA; Fairchild, RG; Fand, I; Glass, JD; Joel, DD; Micca, PL	1
Kowada, M; Mineura, K; Shishido, F	1
Fujita, H; Higano, S; Inugami, A; Kanno, I; Miura, S; Murakami, M; Sasaki, H; Shishido, F; Takahashi, K; Tomura, N	1
Richelson, E	1
Brecher, AS; König, M; Pugatch, RD; Sobel, RE; Suszkiw, JB; Wasilauskas, VP	1

Reviews

1 review(s) available for phenylalanine and Glioma

Article	Year
Boron neutron capture therapy at the crossroads: challenges and opportunities. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fast Neutrons; Glioma; Humans; Nuclear Reactors; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Rats; Sulfhydryl Compounds	2009

Article

Year

Boron neutron capture therapy at the crossroads: challenges and opportunities.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fast Neutrons; Glioma; Humans; Nuclear Reactors; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Rats; Sulfhydryl Compounds

2009

Trials

3 trial(s) available for phenylalanine and Glioma

Article	Year
Optimization of time frame binning for FDOPA uptake quantification in glioma. PloS one, 2020, Volume: 15, Issue:4 Topics: Adult; Aged; Biological Transport; Brain; Brain Neoplasms; Female; Glioma; Humans; Kinetics; Male; Middle Aged; Monte Carlo Method; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Young Adult	2020
A cancer research UK pharmacokinetic study of BPA-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Aged; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Male; Mannitol; Phenylalanine; Radiation-Sensitizing Agents; United Kingdom	2009
Intra-individual comparison of p-[123I]-iodo-L-phenylalanine and L-3-[123I]-iodo-alpha-methyl-tyrosine for SPECT imaging of gliomas. European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:1 Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Count; Female; Glioma; Humans; Male; Methyltyrosines; Middle Aged; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon	2008

Other Studies

54 other study(ies) available for phenylalanine and Glioma

Article	Year
Bio-piezoelectric phenylalanine-αβ-dehydrophenylalanine nanotubes as potential modalities for combinatorial electrochemotherapy in glioma cells. Biomaterials science, 2023, May-16, Volume: 11, Issue:10 Topics: Cell Line, Tumor; Dipeptides; Doxorubicin; Electrochemotherapy; Glioma; Humans; Nanotubes; Phenylalanine; Reactive Oxygen Species	2023
Thermal Sensitive Liposomes Improve Delivery of Boronated Agents for Boron Neutron Capture Therapy. Pharmaceutical research, 2019, Aug-07, Volume: 36, Issue:10 Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Central Nervous System Neoplasms; Doxorubicin; Drug Liberation; Female; Glioma; Humans; Hyperthermia, Induced; Liposomes; Mice, Nude; Nitroimidazoles; Particle Size; Phenylalanine; Phospholipids; Temperature; Tissue Distribution	2019
A periodic development of BPA and BSH based derivatives in boron neutron capture therapy (BNCT). Chemical communications (Cambridge, England), 2021, Jan-28, Volume: 57, Issue:7 Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Boron Neutron Capture Therapy; Coordination Complexes; Glioma; Liposomes; Mice; Peptides; Phenylalanine	2021
Boron phenyl alanine targeted ionic liquid decorated chitosan nanoparticles for mitoxantrone delivery to glioma cell line. Pharmaceutical development and technology, 2021, Volume: 26, Issue:8 Topics: Antineoplastic Agents; Boron; Cell Line, Tumor; Chitosan; Glioma; Humans; Microscopy, Electron, Transmission; Mitoxantrone; Nanoparticle Drug Delivery System; Nanoparticles; Phenylalanine	2021
Sequence length dependence in arginine/phenylalanine oligopeptides: Implications for self-assembly and cytotoxicity. Biophysical chemistry, 2018, Volume: 233 Topics: Animals; Arginine; Cell Survival; Dose-Response Relationship, Drug; Glioma; Macrophages; Mice; Oligopeptides; Particle Size; Phenylalanine; Rats; RAW 264.7 Cells; Structure-Activity Relationship	2018
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2. Annals of nuclear medicine, 2019, Volume: 33, Issue:6 Topics: Animals; Blood Circulation; Boron Compounds; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Humans; Large Neutral Amino Acid-Transporter 1; Male; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Rats; Tissue Distribution; Tyrosine	2019
Radiosynthesis and biological evaluation of alpha-[F-18]fluoromethyl phenylalanine for brain tumor imaging. Nuclear medicine and biology, 2013, Volume: 40, Issue:4 Topics: Animals; Biological Transport; Brain Neoplasms; Glioma; Male; Mice; Multimodal Imaging; Neoplasm Grading; Phenylalanine; Radiochemistry; Radionuclide Imaging	2013
Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Animals; Boron Compounds; Brain Neoplasms; Drug Synergism; Female; Glioma; Levodopa; Melanoma; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Organ Specificity; Phenylalanine; Premedication; Tissue Distribution; Treatment Outcome	2014
Pharmacokinetic analysis and uptake of 18F-FBPA-Fr after ultrasound-induced blood-brain barrier disruption for potential enhancement of boron delivery for neutron capture therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:4 Topics: Animals; Apoptosis; Blood-Brain Barrier; Boron Compounds; Brain Neoplasms; Drug Delivery Systems; Glioma; Glycopeptides; In Situ Nick-End Labeling; Male; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Ultrasonics	2014
Tetrakis(p-carboranylthio-tetrafluorophenyl)chlorin (TPFC): application for photodynamic therapy and boron neutron capture therapy. Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:3 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioma; Male; Microscopy, Fluorescence; Phenylalanine; Photochemotherapy; Photosensitizing Agents; Porphyrins; Radiation-Sensitizing Agents; Rats, Inbred F344; Tissue Distribution	2015
L-DOPA preloading increases the uptake of borophenylalanine in C6 glioma rat model: a new strategy to improve BNCT efficacy. International journal of radiation oncology, biology, physics, 2008, Oct-01, Volume: 72, Issue:2 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dopamine Agents; Glioma; Levodopa; Male; Phenylalanine; Rats	2008
Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioma; In Vitro Techniques; Levodopa; Magnetic Resonance Imaging; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar	2009
In vivo 19F MR imaging and spectroscopy for the BNCT optimization. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Fluorine; Glioma; In Vitro Techniques; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Tissue Distribution	2009
PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Algorithms; Astrocytoma; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carbon Radioisotopes; Glioblastoma; Glioma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted	2009
Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioma; Head and Neck Neoplasms; Humans; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Rats; Rats, Inbred F344	2009
Efficacy of systemic radionuclide therapy with p-131I-iodo-L-phenylalanine combined with external beam photon irradiation in treating malignant gliomas. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Volume: 50, Issue:12 Topics: Animals; Cell Line, Tumor; Glioma; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Phenylalanine; Photons; Rats; Survival Rate	2009
Synthesis and analysis of 2-[211At]-L-phenylalanine and 4-[211At]-L-phenylalanine and their uptake in human glioma cell cultures in-vitro. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2010, Volume: 68, Issue:6 Topics: Astatine; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Isotope Labeling; Phenylalanine; Radiopharmaceuticals	2010
Prospective study of p-[123I]iodo-L-phenylalanine and SPECT for the evaluation of newly diagnosed cerebral lesions: specific confirmation of glioma. European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:12 Topics: Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon	2010
Synthesis and comparative biological evaluation of L- and D-isomers of 18F-labeled fluoroalkyl phenylalanine derivatives as tumor imaging agents. Nuclear medicine and biology, 2011, Volume: 38, Issue:3 Topics: Animals; Biological Transport; Cell Line, Tumor; Fluorine Radioisotopes; Glioma; Phenylalanine; Positron-Emission Tomography; Rats; Stereoisomerism; Tyrosine	2011
Selective uptake of boronophenylalanine by glioma stem/progenitor cells. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2012, Volume: 70, Issue:8 Topics: Animals; Boranes; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Phenylalanine; Tissue Distribution	2012
Prognostic and therapeutic indicator of fluoroboronophenylalanine positron emission tomography in patients with gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Dec-01, Volume: 9, Issue:16 Pt 1 Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prognosis; Survival Rate; Tomography, Emission-Computed; Treatment Outcome	2003
Evaluation of 4-borono-2-18F-fluoro-L-phenylalanine-fructose as a probe for boron neutron capture therapy in a glioma-bearing rat model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:2 Topics: Animals; Autoradiography; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fluorine Radioisotopes; Fructose; Glioma; Male; Phenylalanine; Rats; Rats, Inbred F344; Tissue Distribution; Tomography, Emission-Computed	2004
MicroPET-based pharmacokinetic analysis of the radiolabeled boron compound [18F]FBPA-F in rats with F98 glioma. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5 Topics: Animals; Boron Compounds; Brain Neoplasms; Fluorine Radioisotopes; Fructose; Glioma; Humans; Male; Phenylalanine; Positron-Emission Tomography; Rats; Rats, Inbred F344	2004
Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Glioma; Humans; Injections, Intravenous; Phenylalanine; Radiotherapy Dosage; Rats; Rats, Inbred F344; Recombinant Proteins; Tissue Distribution; Transfection	2004
Accumulation of boron in human malignant glioma cells in vitro is cell type dependent. Journal of neuro-oncology, 2004, Volume: 68, Issue:3 Topics: Boranes; Boron; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Cell Line, Tumor; Fibroblasts; Glioblastoma; Glioma; Humans; Phenylalanine	2004
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors. Cancer research, 2004, Sep-01, Volume: 64, Issue:17 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Division; Glioma; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Middle Aged; Phenylalanine; Phosphorylation; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion; Subcellular Fractions; Thymidine; Thymidine Kinase	2004
Evaluation of pharmacokinetics of 4-borono-2-(18)F-fluoro-L-phenylalanine for boron neutron capture therapy in a glioma-bearing rat model with hyperosmolar blood-brain barrier disruption. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:11 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Glioma; Injections, Intra-Arterial; Male; Mannitol; Metabolic Clearance Rate; Organ Specificity; Osmolar Concentration; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution	2005
Capillary electrophoresis-electrospray mass spectrometry and HR-ICP-MS for the detection and quantification of 10B-boronophenylalanine (10B-BPA) used in boron neutron capture therapy. Analytical and bioanalytical chemistry, 2006, Volume: 384, Issue:3 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Electrophoresis, Capillary; Endothelial Cells; Glioma; Humans; Isotopes; Mass Spectrometry; Molecular Structure; Phenylalanine; Rats; Sensitivity and Specificity; Time Factors	2006
Pharmacokinetic study of BSH and BPA in simultaneous use for BNCT. Journal of neuro-oncology, 2006, Volume: 78, Issue:3 Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Drug Combinations; Drug Synergism; Glioma; Male; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Wistar; Statistics, Nonparametric; Sulfhydryl Compounds	2006
Biological evaluation of fluorinated p-boronophenylalanine derivatives as a boron carrier. Protein and peptide letters, 2007, Volume: 14, Issue:3 Topics: Animals; Antineoplastic Agents; Boron; Boron Compounds; Cell Survival; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Glioma; Hydrocarbons, Fluorinated; Ion Transport; Models, Biological; Phenylalanine; Rats; Solubility; Tumor Cells, Cultured	2007
PET imaging with p-[I-124]iodo-l-phenylalanine as a new tool for diagnosis and postoperative control in patients with glioma. Clinical nuclear medicine, 2008, Volume: 33, Issue:6 Topics: Aged; Brain Neoplasms; Female; Glioma; Humans; Phenylalanine; Positron-Emission Tomography; Postoperative Care; Radiopharmaceuticals	2008
Cellular binding of carboranylalanine and some effects of boron neutron capture. Analysis of cultured melanoma B16 cells. Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:6 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Survival; Glioma; Humans; Melanins; Melanoma; Melanoma, Experimental; Phenylalanine; Protein Binding; Tumor Cells, Cultured	1994
The pharmacokinetics of p-Boronophenylalanine.fructose in human patients with glioma and metastatic melanoma. International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents	1994
Neutron capture therapy of a rat glioma using boronophenylalanine as a capture agent. Radiation research, 1994, Volume: 137, Issue:1 Topics: Animals; Boron Compounds; Brain; Cell Survival; Dose-Response Relationship, Radiation; Glioma; Male; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Survival Analysis; Time Factors; Tissue Distribution; Tumor Cells, Cultured; X-Rays	1994
Hydroxylforms of p-boronophenylalanine as potential boron carriers on boron neutron capture therapy for malignant brain tumors. Cancer research, 1996, May-01, Volume: 56, Issue:9 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Survival; Glioma; Humans; Hydroxylation; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344	1996
Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption. Neurosurgery, 1996, Volume: 38, Issue:5 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Brain; Brain Neoplasms; Carotid Arteries; Dominance, Cerebral; Glioma; Injections, Intra-Arterial; Mannitol; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution; Tumor Cells, Cultured	1996
Quantitative evaluation of neutral amino acid transport in cerebral gliomas using positron emission tomography and fluorine-18 fluorophenylalanine. European journal of nuclear medicine, 1996, Volume: 23, Issue:8 Topics: Amino Acids; Biological Transport, Active; Brain; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Male; Middle Aged; Phenylalanine; Tomography, Emission-Computed	1996
Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption. Cancer research, 1997, Mar-15, Volume: 57, Issue:6 Topics: Alpha Particles; Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Carotid Arteries; Glioma; Injections, Intra-Arterial; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Sulfhydryl Compounds	1997
Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine. Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carotid Arteries; Fructose; Glioma; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Male; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution	1997
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:2 Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed	1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part I. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed	1998
Positron emission tomography-based boron neutron capture therapy using boronophenylalanine for high-grade gliomas: part II. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:8 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Fluorine Radioisotopes; Glioma; Humans; Isotopes; Mathematical Computing; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed	1998
Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (Receptor-Mediated Permeabilizer-7). Neurosurgery, 1999, Volume: 44, Issue:2 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Carotid Arteries; Dose-Response Relationship, Drug; Glioma; Injections, Intra-Arterial; Injections, Intravenous; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution	1999
Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro. International journal of cancer, 1999, Mar-01, Volume: 80, Issue:5 Topics: Animals; Brain; Cell Aggregation; Cell Division; Collagenases; Enzyme Inhibitors; Fetus; Gelatinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Metalloendopeptidases; Neoplasm Invasiveness; Neurons; Phenylalanine; Rats; Rats, Inbred Strains; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator	1999
Boron neutron capture therapy of brain tumors: enhanced survival and cure following blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine. International journal of radiation oncology, biology, physics, 2000, Apr-01, Volume: 47, Issue:1 Topics: Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Injections, Intra-Arterial; Phenylalanine; Radiation-Sensitizing Agents; Radiobiology; Radiotherapy Dosage; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Time Factors	2000
Improved survival after boron neutron capture therapy of brain tumors by Cereport-mediated blood-brain barrier modulation to enhance delivery of boronophenylalanine. Neurosurgery, 2000, Volume: 47, Issue:1 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Glioma; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution	2000
Characterization of 3-[(123)I]iodo-L-alpha-methyl tyrosine transport in astrocytes of neonatal rats. Journal of neurochemistry, 2001, Volume: 76, Issue:1 Topics: alpha-Methyltyrosine; Amino Acid Transport Systems; Amino Acids, Cyclic; Animals; Animals, Newborn; Astrocytes; beta-Alanine; Binding, Competitive; Biological Transport; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Glioma; Leucine; Methyltyrosines; Phenylalanine; Radiopharmaceuticals; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2001
Boron neutron capture therapy for murine malignant gliomas. Cancer research, 1992, Sep-01, Volume: 52, Issue:17 Topics: Animals; Boron Compounds; Brain; Brain Neoplasms; Glioma; Mice; Mice, Inbred C57BL; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Survival Analysis	1992
Control of intracerebral gliosarcomas in rats by boron neutron capture therapy with p-boronophenylalanine. Radiation research, 1992, Volume: 129, Issue:3 Topics: Animals; Boron Compounds; Brain Neoplasms; Glioma; Male; Neoplasm Transplantation; Neutrons; Phenylalanine; Rats; Rats, Inbred F344	1992
Selective delivery of boron by the melanin precursor analogue p-boronophenylalanine to tumors other than melanoma. Cancer research, 1990, Jan-01, Volume: 50, Issue:1 Topics: Animals; Boron Compounds; Brain Neoplasms; Cell Line; Drug Carriers; Glioma; Humans; Isotopes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neutrons; Phenylalanine; Rats; Tissue Distribution; Transplantation, Heterologous	1990
Brain tumor imaging with synthesized 18F-fluorophenylalanine and positron emission tomography. Surgical neurology, 1989, Volume: 31, Issue:6 Topics: Astrocytoma; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Middle Aged; p-Fluorophenylalanine; Phenylalanine; Tomography, Emission-Computed	1989
[Clinical investigation of 18F-fluorophenylalanine for brain tumor imaging--comparison with 11C-methionine]. Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:12 Topics: Brain; Brain Neoplasms; Carbon Radioisotopes; Female; Fluorine Radioisotopes; Glioma; Humans; Methionine; Middle Aged; p-Fluorophenylalanine; Phenylalanine; Tomography, Emission-Computed	1988
Studies on the transport of L-tyrosine into an adrenergic clone of mouse neuroblastoma. The Journal of biological chemistry, 1974, Oct-10, Volume: 249, Issue:19 Topics: Amino Acids; Animals; Azides; Benzenesulfonates; Biological Transport; Carbon Radioisotopes; Cell Count; Cell Line; Chloromercuribenzoates; Chromatography, Thin Layer; Clone Cells; Dinitrophenols; Electrophoresis, Paper; Glioma; Isomerism; Kinetics; Mice; Neoplasms, Experimental; Neuroblastoma; Osmolar Concentration; Ouabain; Phenylalanine; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase	1974
The hydrolytic activity in normal human and malignant tissue. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:3 Topics: Acid Phosphatase; Adenocarcinoma, Papillary; Alanine; Alkaline Phosphatase; Amides; Amidohydrolases; Arginine; Brain; Carcinoma, Intraductal, Noninfiltrating; Cecal Neoplasms; Cobalt; Dipeptidases; Female; Glioma; Humans; Leucine; Manganese; Naphthalenes; Ovarian Neoplasms; Peptide Hydrolases; Phenylalanine	1969