phenylalanine has been researched along with Disease Exacerbation in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.41) | 18.2507 |
| 2000's | 13 (35.14) | 29.6817 |
| 2010's | 16 (43.24) | 24.3611 |
| 2020's | 6 (16.22) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, SH; Kang, JS; Kim, HJ; Kim, KS; Kim, WJ; Ramakrishna, S; Sarodaya, N; Singh, V; Tyagi, A | 1 |
| Chang, S; Chu, X; Ding, J; Du, C; Feng, T; Ge, C; Geng, M; Gong, Y; Huang, X; Lian, W; Lin, F; Liu, J; Ruan, L; Sun, G; Wang, H; Wang, T; Wang, X; Xiao, S; Xie, Z; Yan, S; Yang, D; Yang, J; Zhang, G; Zhang, H; Zhang, J; Zhang, Q | 1 |
| Felson, DT; Guermazi, A; Lewis, CE; Liu, M; Nevitt, MC; Rahman, P; Randell, EW; Roemer, F; Sun, X; Tolstykh, I; Torner, J; Wang, N; Zhai, G | 1 |
| Cheng, ML; Lai, MW; Liang, KH; Lin, WR; Lin, YH; Lo, CJ; Yeh, CT | 1 |
| Dharmasivam, M; Park, KC; Richardson, DR | 1 |
| Alegre, A; Anderson, KC; Bakker, NA; Bladé, J; Byrne, C; Cavo, M; Harmenberg, J; Hassoun, H; Hiemenz, JW; Larocca, A; Laubach, JP; Leleu, X; Maisel, C; Mateos, MV; Mazumder, A; Moreb, JS; Nadeem, O; Oriol, A; Paner, A; Raptis, A; Richardson, PG; Rodriguez-Otero, P; Thuresson, M; Thuresson, S; Touzeau, C | 1 |
| Abdel-Hamid, AZ; El-Maraghy, SA; Hanafy, MM; Lindeque, JZ; Shahin, NN | 1 |
| Álvarez-Larrán, A; Angona, A; Bellosillo, B; Besses, C; Camacho, L; Fernández-Rodríguez, C; Longarón, R; Senín, A | 1 |
| Brunet-Vega, A; Calvet, X; Gombau, L; Junquera, F; Lario, S; Pericay, C; Quintás, G; Ramírez-Lázaro, MJ; Sanjuan-Herráez, D | 1 |
| Anthony, DC; Claridge, TDW; Jagielowicz, M; Probert, F; Simmons, A; Travis, S; Walsh, A; Yeo, T | 1 |
| Bai, S; Sun, P; Wang, C; Ye, R; Zhao, L | 1 |
| Kataoka, Y; Kimura, K; Kosuge, M; Miyamoto, Y; Miyazaki, S; Sase, K; Yasuda, S; Yoshimasa, Y | 1 |
| Burton, BK; Dimmock, D; Feigenbaum, A; Jurecki, E; Lang, W; Longo, N; Prasad, S; Siriwardena, K; Stockler, S; Waisbren, S; Zhang, C | 1 |
| Dirnhofer, S; Duek, A; Grisouard, J; Hao-Shen, H; Kubovcakova, L; Shimizu, T; Skoda, RC | 1 |
| Carsten, CG; Chowdhury, A; Gerard, P; Gray, BH; Nahar-Gohad, P; Nosoudi, N; Sinha, A; Vyavahare, NR | 1 |
| Alvfors, C; Berglund, Å; Gullbo, J; Hagberg, H; Harmenberg, J; Jerling, M; Lewensohn, R; Lisyanskaya, A; Nordström, E; Nygren, P; Orlov, S; Ringbom, M; Söderlind, K; Spira, J; Tholander, B; Ullén, A | 1 |
| Atula, T; Haapaniemi, A; Joensuu, H; Kankaanranta, L; Koivunoro, H; Mäkitie, A; Saarilahti, K; Saat, R | 1 |
| Ambler, K; Casolari, DA; D'Andrea, RJ; Nguyen, T; Ross, DM; Tiong, IS; Van Velzen, MJ | 1 |
| Singh, V | 1 |
| Bethel, M; Boolell, M; Califf, RM; Duggal, A; Haffner, SM; Holman, RR; McMurray, J | 1 |
| Adams, JR; Ely, EW; Girard, TD; Morandi, A; Pandharipande, PP; Shintani, AK; Thompson, JL | 1 |
| Amyere, M; Girardot, M; Knoops, L; Michaux, L; Selleslag, D; van Hees, J | 1 |
| Blakely, EL; Carter, JE; de Silva, RN; Kartsounis, LD; O'Donovan, DG; Swalwell, H; Taylor, RW; Turnbull, DM; Young, TM | 1 |
| Gosmanov, AR; Umpierrez, GE; Westerhaus, B | 1 |
| Dal Cin, P; Hernandez, JM; Kuo, FC; Leon, A; Longtine, JA; Staropoli, JF | 1 |
| Lee, SR; Lo, EH; Tsuji, K | 1 |
| Björnsson, MJ; Havemose-Poulsen, A; Holmstrup, P; Stoltze, K | 1 |
| Devy, L; Foidart, JM; Frankenne, F; Grams, F; Krell, HW; Maquoi, E; Noël, A; Olivier, F; Sounni, NE | 1 |
| Didziapetriene, J; Kadziauskas, J; Stanciūte, D | 1 |
| Förbs, D; Schweinitz, A; Steinmetzer, T; Stella, MC; Stürzebecher, A; Stürzebecher, J; Thiel, S; Uhland, K | 1 |
| Baccarani, M; Bosi, C; Castagnetti, F; Cilloni, D; Colarossi, S; Giannoulia, P; Gnani, A; Iacobucci, I; Luatti, S; Martinelli, G; Marzocchi, G; Palandri, F; Paolini, S; Piccaluga, PP; Rondoni, M; Rosti, G; Saglio, G; Soverini, S; Testoni, N | 1 |
| Barcikowska, M; Filipek, S; Golan, MP; Jóźwiak, K; Lugiewicz, R; Maruszak, A; Pniewski, J; Styczyńska, M; Walecki, J; Zekanowski, C | 1 |
| Belal, S; Dhondt, JL; Hentati, F; Kaabachi, N; Larnaout, A; Mebazza, A; Miladi, N | 1 |
| Bergers, G; Folkman, J; Hanahan, D; Javaherian, K; Lo, KM | 1 |
| Jinnah, HA; Kasim, S; Moo, LR; Zschocke, J | 1 |
| Brown, AJ; Dean, RT; Kettle, AJ; Mashima, R; Niu, X; Senthilmohan, R; Stocker, R; Upston, JM; Wang, H | 1 |
| Ackermann, J; Assmann, I; Drach, J; Hübl, W; Ludwig, H; Schuster-Kolbe, J; Strasser, K; Zojer, N | 1 |
3 review(s) available for phenylalanine and Disease Exacerbation
| Article | Year |
|---|---|
The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators that Inhibit their Activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; Disease Progression; Drug Design; Drug Screening Assays, Antitumor; Extracellular Fluid; Extracellular Vesicles; Humans; Hydroxamic Acids; Iron; Iron Chelating Agents; Kallikreins; Matrix Metalloproteinases; Molecular Targeted Therapy; Neoplasm Proteins; Oxaprozin; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Protein Kinases; Pyridines; Thiophenes; Thiosemicarbazones; Zinc | 2020 |
Diabetes prevention: can insulin secretagogues do the job?
Topics: Benzamides; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Type 2; Disease Progression; Evidence-Based Medicine; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Nateglinide; Phenylalanine; Preventive Health Services; Sulfonylurea Compounds; Treatment Outcome | 2011 |
[Expression of matrix metalloproteinases in patients with malignant tumors].
Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Clinical Trials as Topic; Diphosphonates; Disease Progression; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasms; Organic Chemicals; Phenylalanine; Phenylbutyrates; Prognosis; Protease Inhibitors; Thiophenes; Time Factors; Tissue Inhibitor of Metalloproteinases | 2004 |
4 trial(s) available for phenylalanine and Disease Exacerbation
| Article | Year |
|---|---|
Melflufen and Dexamethasone in Heavily Pretreated Relapsed and Refractory Multiple Myeloma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Disease Progression; Drug Resistance, Neoplasm; Europe; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Phenylalanine; Progression-Free Survival; Recurrence; Time Factors; United States | 2021 |
Long-term developmental progression in infants and young children taking sapropterin for phenylketonuria: a two-year analysis of safety and efficacy.
Topics: Biopterins; Child; Child Development; Child, Preschool; Cognition; Disease Progression; Female; Humans; Infant; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Prospective Studies; Time Factors; Treatment Outcome | 2015 |
First-in-human, phase I/IIa clinical study of the peptidase potentiated alkylator melflufen administered every three weeks to patients with advanced solid tumor malignancies.
Topics: Adult; Aged; Aged, 80 and over; Alkylation; Antineoplastic Agents, Alkylating; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Male; Melphalan; Middle Aged; Neoplasms; Peptide Hydrolases; Phenylalanine; Prospective Studies | 2015 |
Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cyclohexanes; Diabetic Angiopathies; Disease Progression; Double-Blind Method; Glucose Intolerance; Humans; Hypoglycemic Agents; Life Style; Nateglinide; Outcome Assessment, Health Care; Phenylalanine; Research Design; Tetrazoles; Valine; Valsartan | 2008 |
30 other study(ies) available for phenylalanine and Disease Exacerbation
| Article | Year |
|---|---|
Deubiquitinase USP19 extends the residual enzymatic activity of phenylalanine hydroxylase variants.
Topics: Animals; Asian People; Deubiquitinating Enzymes; Disease Progression; Endopeptidases; Humans; Mammals; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias | 2022 |
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.
Topics: Alzheimer Disease; Amino Acids; Animals; Anti-Bacterial Agents; Bacteria; Clinical Trials, Phase III as Topic; Cognitive Dysfunction; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Humans; Isoleucine; Mannose; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Oligosaccharides; Phenylalanine; Th1 Cells | 2019 |
Phenylalanine Is a Novel Marker for Radiographic Knee Osteoarthritis Progression: The MOST Study.
Topics: Disease Progression; Female; Humans; Knee Joint; Male; Osteoarthritis, Knee; Phenylalanine; Radiography | 2021 |
Plasma phenylalanine and glutamine concentrations correlate with subsequent hepatocellular carcinoma occurrence in liver cirrhosis patients: an exploratory study.
Topics: Age Factors; Aged; Area Under Curve; Carcinoma, Hepatocellular; Chromatography, Liquid; Cross-Sectional Studies; Disease Progression; Female; Glutamine; Humans; Liver Cirrhosis; Male; Middle Aged; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Prodromal Symptoms; Prospective Studies; Risk; ROC Curve | 2020 |
Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.
Topics: Animals; Biomarkers; Carnitine; Cluster Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Progression; Fructose; Fucose; Galactose; Glycosuria; Inositol; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Phenylalanine; Rats; Rats, Wistar; Streptozocin; Taurine; Time Factors | 2021 |
Non-driver mutations in patients with JAK2V617F-mutated polycythemia vera or essential thrombocythemia with long-term molecular follow-up.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Cell Transformation, Neoplastic; Cytogenetic Analysis; Disease Progression; Female; Follow-Up Studies; Gene Frequency; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polycythemia Vera; Thrombocythemia, Essential; Valine | 2018 |
Plasma sample based analysis of gastric cancer progression using targeted metabolomics.
Topics: Adult; Aged; Biomarkers, Tumor; Disease Progression; Female; Gastritis; Helicobacter Infections; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Middle Aged; Phenylalanine; Plasma; Stomach; Stomach Neoplasms; Tryptophan | 2017 |
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult | 2018 |
Identification of proteomic signatures associated with COPD frequent exacerbators.
Topics: Aged; Biglycan; Chromatography, Liquid; Cluster Analysis; Computational Biology; Databases, Genetic; Disease Progression; Female; HLA-DQ alpha-Chains; Humans; Immunoglobulin A; Lung; Male; Middle Aged; Phenotype; Phenylalanine; Proteomics; Pulmonary Disease, Chronic Obstructive; Receptors, Polymeric Immunoglobulin; Tandem Mass Spectrometry; Transcriptome | 2019 |
Clinical predictors of atheroma progression despite optimal glycemic control in early-stage diabetic patients with coronary artery disease: Insight from the DIANA study.
Topics: Blood Glucose; Coronary Angiography; Coronary Artery Disease; Cyclohexanes; Diabetes Mellitus; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inositol; Life Style; Male; Middle Aged; Nateglinide; Phenylalanine; Plaque, Atherosclerotic; Prospective Studies; Risk Factors; Ultrasonography, Interventional | 2014 |
Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN.
Topics: Amino Acid Substitution; Animals; Bone Marrow; Bone Marrow Neoplasms; Disease Models, Animal; Disease Progression; Gene Deletion; Hematopoietic Stem Cells; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloproliferative Disorders; Phenylalanine; STAT3 Transcription Factor; Thrombocytosis; Valine | 2015 |
Prevention of abdominal aortic aneurysm progression by targeted inhibition of matrix metalloproteinase activity with batimastat-loaded nanoparticles.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Chemistry, Pharmaceutical; Disease Models, Animal; Disease Progression; Drug Carriers; Elastin; Immunoconjugates; Macrophages; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Nanoparticles; Phenylalanine; Polyesters; Proteolysis; Rats, Sprague-Dawley; RAW 264.7 Cells; Thiophenes; Time Factors; Vascular Calcification | 2015 |
Boron Neutron Capture Therapy in the Treatment of Recurrent Laryngeal Cancer.
Topics: Aged; Aged, 80 and over; Boron Compounds; Boron Neutron Capture Therapy; Carcinoma, Squamous Cell; Compassionate Use Trials; Disease Progression; Female; Glottis; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organ Sparing Treatments; Phenylalanine; Radiotherapy Dosage; Re-Irradiation; Time Factors; Tumor Burden | 2016 |
Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Asymptomatic Diseases; Cohort Studies; Disease Progression; Female; Genetic Predisposition to Disease; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polycythemia Vera; Polymorphism, Single Nucleotide; Prodromal Symptoms; Thrombocythemia, Essential; Valine | 2016 |
DCoH: A novel biomarker for diagnosing acute kidney injury.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cell Line; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Humans; Hydro-Lyases; Models, Theoretical; Phenylalanine; Prognosis | 2016 |
Plasma tryptophan and tyrosine levels are independent risk factors for delirium in critically ill patients.
Topics: Aged; Amino Acid Transport System L; Analysis of Variance; Critical Illness; Delirium; Disease Progression; Female; Humans; Logistic Models; Male; Markov Chains; Middle Aged; Phenylalanine; Pilot Projects; Predictive Value of Tests; Regression Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Tennessee; Time Factors; Tryptophan; Tyrosine | 2009 |
Analysis of the progression of JAK2 V617F positive myeloproliferative neoplasms by single-nucleotide polymorphism array does not reveal a strong chromosomal instability.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Chromosomal Instability; Disease Progression; Humans; Janus Kinase 2; Middle Aged; Myeloproliferative Disorders; Phenylalanine; Polymorphism, Single Nucleotide; Valine | 2009 |
Mitochondrial transfer RNA(Phe) mutation associated with a progressive neurodegenerative disorder characterized by psychiatric disturbance, dementia, and akinesia-rigidity.
Topics: Atrophy; Brain; Dementia; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mitochondrial Diseases; Muscle Rigidity; Mutation; Neurodegenerative Diseases; Neuropsychological Tests; Phenylalanine; RNA, Transfer | 2010 |
Translocation t(1;9) is a recurrent cytogenetic abnormality associated with progression of essential thrombocythemia patients displaying the JAK2 V617F mutation.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 9; Cohort Studies; Disease Progression; Female; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Recurrence; Thrombocythemia, Essential; Translocation, Genetic; Valine | 2011 |
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.
Topics: Animals; Dipeptides; Disease Models, Animal; Disease Progression; Hippocampus; Immunohistochemistry; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Phenylalanine; Protease Inhibitors; Thiophenes | 2004 |
Influence of the matrix metalloproteinase inhibitor batimastat (BB-94) on periodontal bone destruction in Sprague-Dawley rats.
Topics: Alveolar Bone Loss; Alveolar Process; Analysis of Variance; Animals; Disease Progression; Injections, Intraperitoneal; Male; Matrix Metalloproteinase Inhibitors; Phenylalanine; Placebos; Protease Inhibitors; Radiography, Dental, Digital; Random Allocation; Rats; Rats, Sprague-Dawley; Thiophenes | 2004 |
Anti-invasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Aorta; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Microscopy, Fluorescence; Models, Chemical; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Phenylalanine; Piperazines; Protease Inhibitors; Pyrimidines; Rats; Thiophenes; Time Factors; Up-Regulation | 2004 |
In vitro inhibition of matriptase prevents invasive growth of cell lines of prostate and colon carcinoma.
Topics: Blotting, Western; Catalytic Domain; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Collagen; Colonic Neoplasms; Disease Progression; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Female; Hepatocyte Growth Factor; Humans; In Vitro Techniques; Inhibitory Concentration 50; Kinetics; Laminin; Male; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; Peptide Hydrolases; Phenylalanine; Prostatic Neoplasms; Protein Precursors; Protein Structure, Tertiary; Proteoglycans; RNA, Small Interfering; Serine Endopeptidases; Signal Transduction; Time Factors | 2005 |
Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia.
Topics: Adult; Antineoplastic Agents; Blast Crisis; Clinical Trials, Phase II as Topic; Dasatinib; Disease Progression; Drug Resistance, Neoplasm; Female; Genes, abl; Humans; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mutation; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Treatment Failure | 2006 |
Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene.
Topics: Adult; Alzheimer Disease; Brain; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Models, Molecular; Mutation; Phenylalanine; Presenilin-1; Serine; Time Factors | 2007 |
Juvenile form of dihydropteridine reductase deficiency in 2 Tunisian patients.
Topics: Adult; Age of Onset; Child; Consanguinity; Disease Progression; Follow-Up Studies; Humans; Male; Metabolism, Inborn Errors; Movement Disorders; Neurodegenerative Diseases; Nuclear Family; Phenylalanine; Phenylketonurias; Pteridines | 1998 |
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice.
Topics: Angiostatins; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Islet Cell; Collagen; Cyclohexanes; Disease Progression; Drug Evaluation, Preclinical; Endostatins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Staging; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Pancreatic Neoplasms; Peptide Fragments; Phenylalanine; Plasminogen; Sesquiterpenes; Thiophenes | 1999 |
Phenylketonuria presenting in adulthood as progressive spastic paraparesis with dementia.
Topics: Age of Onset; Cognition; Dementia; Diagnosis, Differential; Diet, Protein-Restricted; Disease Progression; Female; Gait; Genotype; Humans; Magnetic Resonance Imaging; Middle Aged; Mutation; Neuropsychological Tests; Paraparesis, Spastic; Phenotype; Phenylalanine; Phenylketonurias; Treatment Outcome | 2001 |
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis.
Topics: Adult; Aged; Antioxidants; Aorta; Arteriosclerosis; Cholesterol; Cholesterol Esters; Disease Progression; Humans; Lipid Metabolism; Middle Aged; Oxidation-Reduction; Phenylalanine; Proteins; Tyrosine | 2002 |
Chromosomal aberrations are shared by malignant plasma cells and a small fraction of circulating CD19+ cells in patients with myeloma and monoclonal gammopathy of undetermined significance.
Topics: Aged; Aged, 80 and over; Antigens, CD19; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; Clone Cells; Disease Progression; Disulfides; Gene Deletion; Genes, Immunoglobulin; Genes, p53; Genes, Retinoblastoma; Humans; Immunoglobulin G; Immunoglobulin Light Chains; Immunohistochemistry; In Situ Hybridization, Fluorescence; Membrane Glycoproteins; Middle Aged; Multiple Myeloma; Paraproteinemias; Phenylalanine; Plasma Cells; Polymerase Chain Reaction; Proteoglycans; RNA, Messenger; Syndecan-1; Syndecans; T-Lymphocytes | 2002 |