phenylalanine has been researched along with Diarrhea in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (13.16) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 56 (73.68) | 24.3611 |
2020's | 10 (13.16) | 2.80 |
Authors | Studies |
---|---|
Shah, ED | 1 |
Boinpally, R; Breen-Lyles, M; Busciglio, I; Camilleri, M; Carrothers, TJ; Maselli, D; Muslin, A; Nord, SL; Vijayvargiya, P | 1 |
Friedenberg, FK; Piech, G; Reichenbach, ZW; Selby, A | 1 |
Brenner, DM; Sayuk, GS | 1 |
Black, CJ; Ford, AC; Houghton, LA | 1 |
Andrae, DA; Covington, PS; Dove, LS; Lembo, AJ | 1 |
Brenner, DM; Cash, BD; Elmes, SJR; Gutman, CR; Jo, E; Liu, LWC; Sayuk, GS | 2 |
Benson, AB; Dharba, S; Joish, VN; Lapuerta, P; Sapre, D; Strosberg, J | 1 |
Liu, R; Staller, K | 1 |
Heidelbaugh, J; Jones, J; Kuritzky, L; Lacy, B; Lembo, A | 1 |
Abel, JL; Brenner, DM; Burslem, K; Sayuk, GS | 1 |
Andrae, DA; Chey, WD; Covington, PS; Dove, LS | 1 |
Markham, A | 1 |
Cash, BD; Chey, WD; Covington, PS; Dove, LS; Lacy, BE; Lembo, AJ | 1 |
Keating, GM | 1 |
Kulke, MH | 1 |
Júdez, FJ; Vera, I | 1 |
Frech, F; Joish, VN; Lapuerta, P | 2 |
Barkin, JS; Croteau, R | 1 |
Özdener, AE; Rivkin, A | 1 |
Masab, M; Saif, MW | 1 |
Anthony, L; Arnold, K; Bergsland, E; Caplin, M; DiBenedetti, DB; Ervin, C; Evans, E; Hörsch, D; Jackson, S; Kulke, MH; Kunz, P; Lapuerta, P; Law, L; Metz, DC; Öberg, K; Pasieka, J; Pavel, M; Pavlakis, N; Ramage, J; Yang, QM | 1 |
Anthony, LB; Benavent, M; Fleming, D; Fleming, R; Garcia-Carbonero, R; Gross, DJ; Hörsch, D; Jiang, W; Kassler-Taub, K; Kulke, MH; Kunz, PL; Lapuerta, P; Pavel, M; Perros, P; Srirajaskanthan, R; Warner, RRP; Wason, S; Weickert, MO | 1 |
Chandrasekharan, C; Dillon, JS | 1 |
Barbara, G; Barbaro, MR; De Ponti, F; Dothel, G; Raschi, E | 1 |
Anthony, LB; Bergsland, E; Caplin, ME; Grande, E; Hörsch, D; Kaltsas, G; Kittur, A; Kulke, MH; Kunz, PL; Lapuerta, P; Lombard-Bohas, C; Öberg, K; Pavel, M; Ramage, JK; Valle, JW; Weickert, MO; Welin, S; Yang, QM | 1 |
Lyseng-Williamson, KA | 1 |
Akbarali, HI; Dewey, WL; Komla, E; Obeng, S; Selley, DE; Stevens, DL; Wang, H; Zhang, Y; Zheng, Y | 1 |
Kasi, PM | 1 |
Corsetti, M; Pannemans, J | 1 |
Abel, JL; Andrae, DA; Carson, RT | 1 |
Chey, WD; Chuang, E; Earnest, DL; Olden, KW; Paul Nicandro, J; Shringarpure, R | 1 |
Beaumont, JL; Cella, D; Feuilly, M; Hörsch, D; Houchard, A; Hudgens, S; Kulke, MH; Lapuerta, P; Marteau, F; Pavel, M; Ramage, J | 1 |
Anthony, LB; Bergsland, E; Caplin, ME; Dillon, JS; Hörsch, D; Jiang, W; Kassler-Taub, K; Kulke, MH; Lapuerta, P; O'Dorisio, TM; Öberg, K; Pavel, M; Warner, RRP | 1 |
Gunn, D; Major, GAD | 1 |
Lai, SW | 1 |
Benson, AB; Dharba, S; Fish-Steagall, A; Giacalone, S; Joish, VN; Kapoor, K; Lapuerta, P; Perez-Olle, R; Strosberg, J | 1 |
Cash, BD; Covington, PS; Dove, LS; Lacy, BE; Schoenfeld, PS | 2 |
Almenoff, JS; Andrae, D; Covington, PS; Davenport, JM; Dove, LS; Fogel, R; Lembo, A; McIntyre, G; Randall, CW | 1 |
Andrae, DA; Covington, PS; Patrick, DL | 1 |
Banks, P; Bergsland, E; Fleming, D; Frazier, K; Freiman, J; Jackson, J; Kulke, MH; Kvols, L; Lapuerta, P; Law, L; O'Dorisio, T; Phan, A; Sands, A; Yao, JC; Zambrowicz, B | 1 |
Devi, LA; Dove, LS; Fujita, W; Gomes, I; McIntyre, G; Prohaska, D | 1 |
Traynor, K | 1 |
Garnock-Jones, KP | 1 |
Lembo, AJ; Nee, J; Zakari, M | 1 |
Cash, BD; Earnest, DL; Lacy, BE; Rao, T | 1 |
Lacy, BE | 1 |
Álvarez de la Campa, E; Colobran, R; de la Cruz, X; Martín-Nalda, A; Martínez-Gallo, M; Pujol-Borrell, R; Soler-Palacín, P | 1 |
Andrae, DA; Covington, PS; Davenport, JM; Dove, LS; Lacy, BE; Lembo, AJ; Lopez, R; McIntyre, G; Schey, R; Turner, L; Zuckerman, MJ | 1 |
Dickson, I | 1 |
Rivkin, A; Rybalov, S | 1 |
Storr, M | 1 |
Auguste, P; Boehm, KA; Gelhorn, HL; Jackson, J; Jackson, S; Kostelec, J; Kulke, MH; Lapuerta, P; Law, L; O'Dorisio, T; Yang, QM | 1 |
Abenavoli, L; Gasbarrini, A; Ianiro, G; Laterza, L; Scarpellini, E; Tack, J | 1 |
Lacy, BE; Moreau, JC | 1 |
Talley, NJ | 1 |
Weber, HC | 1 |
Anthony, LB; Banks, P; Bergsland, E; Caplin, ME; Fleming, D; Grande, E; Hörsch, D; Jackson, S; Kulke, MH; Kunz, PL; Lapuerta, P; Lombard-Bohas, C; Öberg, K; Pavel, M; Sands, AT; Valle, JW; Warner, RR; Welin, S; Zambrowicz, B | 1 |
Cash, BD; Covington, PS; Dove, LS; Fant, RV; Henningfield, JE | 1 |
Camilleri, M | 1 |
Creppy, E; Dirheimer, G; Röschenthaler, R; Schlegel, M | 1 |
Ball, RO; Bayley, HS | 1 |
Grahame-Smith, DG | 1 |
Duran, M; Ketting, D; van der Heiden, C; Wadman, SK; Wauters, EA | 1 |
Donlon, J; Fottrell, PF | 1 |
Healy, PJ | 1 |
Bianchine, JR; Satterlee, WG; Serpick, A | 1 |
Levine, RJ; Vaidya, AB | 1 |
23 review(s) available for phenylalanine and Diarrhea
Article | Year |
---|---|
Pathophysiology, Differential Diagnosis, and Treatment of Diabetic Diarrhea.
Topics: Antidiarrheals; Autonomic Nervous System Diseases; Blind Loop Syndrome; Celiac Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Diarrhea; Diphenoxylate; Enteric Nervous System; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Inflammation; Inflammatory Bowel Diseases; Interstitial Cells of Cajal; Intestinal Absorption; Intestinal Mucosa; Irritable Bowel Syndrome; Loperamide; Neuroglia; Non-Nutritive Sweeteners; Oxidative Stress; Phenylalanine; Serotonin 5-HT3 Receptor Antagonists | 2019 |
Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea.
Topics: Adult; Carbolines; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life; Rifaximin; United States; United States Food and Drug Administration | 2020 |
Update on Eluxadoline for the Treatment of Irritable Bowel Syndrome with Diarrhea: Patient Selection and Perspectives.
Topics: Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Patient Selection; Phenylalanine | 2020 |
Eluxadoline: A Review in Diarrhoea-Predominant Irritable Bowel Syndrome.
Topics: Adult; Constipation; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Opioid, delta | 2017 |
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome. The SEPD perspective.
Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life; Randomized Controlled Trials as Topic | 2017 |
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome.
Topics: Clinical Trials as Topic; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2017 |
Telotristat ethyl: proof of principle and the first oral agent in the management of well-differentiated metastatic neuroendocrine tumor and carcinoid syndrome diarrhea.
Topics: Administration, Oral; Diarrhea; Female; Humans; Male; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines | 2017 |
Advancements in drug development for diarrhea-predominant irritable bowel syndrome.
Topics: Animals; Benzimidazoles; Diarrhea; Drug and Narcotic Control; Drug Design; Gastrointestinal Agents; Humans; Imidazoles; Internationality; Irritable Bowel Syndrome; Phenylalanine | 2018 |
Telotristat Ethyl: A Review in Carcinoid Syndrome Diarrhoea.
Topics: Diarrhea; Drug Interactions; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Signal Transduction; Somatostatin; Treatment Outcome; Tryptophan Hydroxylase | 2018 |
Telotristat ethyl for the treatment of carcinoid syndrome diarrhea not controlled by somatostatin analogues.
Topics: Clinical Trials as Topic; Diarrhea; Humans; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Somatostatin | 2018 |
Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders?
Topics: Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Defecation; Diarrhea; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Imidazoles; Inflammatory Bowel Diseases; Laxatives; Morphinans; Naltrexone; Narcotic Antagonists; Phenylalanine; Polyethylene Glycols; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Signal Transduction | 2018 |
Chronic diarrhoea in adults: what not to miss.
Topics: Adenocarcinoma; Adenoma; Antidiarrheals; Bile Acids and Salts; Celiac Disease; Chronic Disease; Colorectal Neoplasms; Diarrhea; Exocrine Pancreatic Insufficiency; Feces; Gastrointestinal Agents; Humans; Iatrogenic Disease; Imidazoles; Immunochemistry; Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Leukocyte L1 Antigen Complex; Loperamide; Malabsorption Syndromes; Phenylalanine; Steatorrhea | 2019 |
Eluxadoline: First Global Approval.
Topics: Adult; Animals; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu | 2015 |
Current and emerging drug options in the treatment of diarrhea predominant irritable bowel syndrome.
Topics: Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine; Receptors, Opioid; Rifamycins; Rifaximin | 2015 |
Rifaximin and eluxadoline - newly approved treatments for diarrhea-predominant irritable bowel syndrome: what is their role in clinical practice alongside alosetron?
Topics: Abdominal Pain; Anti-Bacterial Agents; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Narcotic Antagonists; Phenylalanine; Receptors, Opioid; Rifamycins; Rifaximin; Serotonin 5-HT3 Receptor Antagonists | 2016 |
Emerging treatments in neurogastroenterology: eluxadoline - a new therapeutic option for diarrhea-predominant IBS.
Topics: Antidiarrheals; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Pancreatitis; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2016 |
Update on the Management of Diarrhea-Predominant Irritable Bowel Syndrome: Focus on Rifaximin and Eluxadoline.
Topics: Administration, Oral; Diarrhea; Disease Management; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin | 2016 |
Eluxadoline for the treatment of diarrhoea-predominant irritable bowel syndrome.
Topics: Abdominal Pain; Constipation; Diarrhea; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid | 2016 |
Diarrhea-predominant irritable bowel syndrome: Diagnosis, etiology, and new treatment considerations.
Topics: Carbolines; Diarrhea; Disease Management; Humans; Imidazoles; Irritable Bowel Syndrome; Parasympatholytics; Phenylalanine; Rifamycins; Rifaximin; United States | 2016 |
New treatment options for irritable bowel syndrome with predominant diarrhea.
Topics: Anti-Bacterial Agents; Constipation; Diarrhea; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Narcotic Antagonists; Phenylalanine; Quality of Life; Receptors, Opioid; Rifamycins; Rifaximin | 2017 |
LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin.
Topics: Animals; Biphenyl Compounds; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Phenylalanine; Receptors, Serotonin; Serotonin; Tryptophan Hydroxylase | 2011 |
Pharmacology of the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Bradykinin; Diarrhea; Drug Synergism; Humans; Kinins; Malignant Carcinoid Syndrome; Methysergide; Neurologic Manifestations; Phenylalanine; Prostaglandins; Serotonin; Serotonin Antagonists; Skin Manifestations | 1968 |
Progress report: the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydroxyindoleacetic Acid; Kallikreins; Liver Neoplasms; Malignant Carcinoid Syndrome; Methyldopa; Methysergide; Neoplasm Metastasis; Phenoxybenzamine; Phenylalanine; Serotonin | 1970 |
16 trial(s) available for phenylalanine and Diarrhea
Article | Year |
---|---|
Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials.
Topics: Abdominal Pain; Adult; Aged; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Treatment Outcome | 2020 |
Early response predicts a sustained response to eluxadoline in patients with irritable bowel syndrome with diarrhoea in two Phase 3 studies.
Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Prognosis; Retrospective Studies; Time Factors | 2017 |
Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use.
Topics: Abdominal Pain; Adult; Antidiarrheals; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Pain Measurement; Phenylalanine; Symptom Assessment | 2017 |
Understanding the Patient Experience with Carcinoid Syndrome: Exit Interviews from a Randomized, Placebo-controlled Study of Telotristat Ethyl.
Topics: Diarrhea; Double-Blind Method; Female; Humans; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome | 2017 |
Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial.
Topics: Adult; Aged; Aged, 80 and over; Diarrhea; Double-Blind Method; Female; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Somatostatin; Treatment Outcome | 2018 |
Changes in Weight Associated With Telotristat Ethyl in the Treatment of Carcinoid Syndrome.
Topics: Aged; Body Weight; Diarrhea; Double-Blind Method; Female; Humans; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome; Tryptophan Hydroxylase | 2018 |
Relationship Between Symptoms and Health-related Quality-of-life Benefits in Patients With Carcinoid Syndrome: Post Hoc Analyses From TELESTAR.
Topics: Aged; Diarrhea; Double-Blind Method; Female; Humans; Male; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Quality of Life; Treatment Outcome; Tryptophan Hydroxylase | 2018 |
TELEPRO: Patient-Reported Carcinoid Syndrome Symptom Improvement Following Initiation of Telotristat Ethyl in the Real World.
Topics: Aged; Cohort Studies; Diarrhea; Female; Follow-Up Studies; Humans; International Agencies; Male; Malignant Carcinoid Syndrome; Patient Reported Outcome Measures; Phenylalanine; Prognosis; Pyrimidines | 2019 |
Efficacy and Safety of Eluxadoline in Patients With Irritable Bowel Syndrome With Diarrhea Who Report Inadequate Symptom Control With Loperamide: RELIEF Phase 4 Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Phenylalanine; Prospective Studies | 2019 |
Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study.
Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Treatment Outcome | 2013 |
Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Diarrhea; Female; Gastrointestinal Agents; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Octreotide; Phenylalanine; Pyrimidines; Serotonin Antagonists; Treatment Outcome | 2014 |
Eluxadoline for Irritable Bowel Syndrome with Diarrhea.
Topics: Abdominal Pain; Adult; Aged; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Pancreatitis; Phenylalanine | 2016 |
[A new remedy for diarrheal irritable bowel syndrome].
Topics: Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; United States | 2016 |
Patient-reported Symptom Experiences in Patients With Carcinoid Syndrome After Participation in a Study of Telotristat Etiprate: A Qualitative Interview Approach.
Topics: Aged; Antineoplastic Agents; Diarrhea; Female; Humans; Interviews as Topic; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome | 2016 |
Telotristat Ethyl, a Tryptophan Hydroxylase Inhibitor for the Treatment of Carcinoid Syndrome.
Topics: Aged; Antineoplastic Agents, Hormonal; Defecation; Diarrhea; Double-Blind Method; Female; gamma-Glutamyltransferase; Gastrointestinal Agents; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Nausea; Octreotide; Peptides, Cyclic; Phenylalanine; Pyrimidines; Somatostatin; Tryptophan Hydroxylase | 2017 |
Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea.
Topics: Abdominal Pain; Adult; Aged; Constipation; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Nausea; Pancreatitis; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spasm; Sphincter of Oddi Dysfunction | 2017 |
37 other study(ies) available for phenylalanine and Diarrhea
Article | Year |
---|---|
Delta Variant: Expanding the Indication for Eluxadoline to Bile Acid Diarrhea.
Topics: Bile Acids and Salts; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2022 |
Safety and Efficacy of Eluxadoline in Patients with Irritable Bowel Syndrome-Diarrhea With or Without Bile Acid Diarrhea: Open-Label Study.
Topics: Adult; Bile Acids and Salts; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life | 2022 |
Efficacy of Eluxadoline in Irritable Bowel Syndrome With Diarrhea.
Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine | 2020 |
Response to Black et al.
Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine | 2020 |
Clinical Benefits of Telotristat Ethyl in Patients With Neuroendocrine Tumors and Low Bowel Movement Frequency: An Observational Patient-Reported Outcomes Study.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Child; Child, Preschool; Defecation; Diarrhea; Female; Flushing; Humans; Infant; Infant, Newborn; Male; Malignant Carcinoid Syndrome; Middle Aged; Nausea; Patient Reported Outcome Measures; Phenylalanine; Pyrimidines; Recovery of Function; Time Factors; Treatment Outcome; Young Adult | 2020 |
Management of irritable bowel syndrome with diarrhea: focus on eluxadoline.
Topics: Adult; Aged; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2021 |
Improved work productivity and health-related quality of life in patients with irritable bowel syndrome with diarrhea receiving eluxadoline following inadequate response to loperamide.
Topics: Absenteeism; Adolescent; Adult; Aged; Aged, 80 and over; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Phenylalanine; Quality of Life; Surveys and Questionnaires; United States; Young Adult | 2021 |
Telotristat Ethyl: First Global Approval.
Topics: Animals; Diarrhea; Drug Approval; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Somatostatin; Tryptophan Hydroxylase; United States; United States Food and Drug Administration | 2017 |
Advances in the management of patients with carcinoid syndrome.
Topics: Carcinoid Tumor; Clinical Trials, Phase III as Topic; Diarrhea; Humans; Malignant Carcinoid Syndrome; Phenylalanine; Pyrimidines | 2017 |
Telotristat ethyl (Xermelo) for carcinoid syndrome diarrhea.
Topics: Antidiarrheals; Diarrhea; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Octreotide; Phenylalanine; Pyrimidines; Treatment Outcome | 2017 |
Τ Eluxadoline for IBS-D.
Topics: Contraindications, Drug; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2017 |
Cost-effectiveness analysis of telotristat ethyl for treatment of carcinoid syndrome diarrhea inadequately controlled with somatostatin analogs.
Topics: Adult; Aged; Cost-Benefit Analysis; Diarrhea; Drug Costs; Drug Therapy, Combination; Female; Health Resources; Humans; Male; Malignant Carcinoid Syndrome; Markov Chains; Middle Aged; Phenylalanine; Pyrimidines; Quality-Adjusted Life Years; Somatostatin; Treatment Outcome; United States | 2018 |
Safety of Eluxadoline in Patients With Irritable Bowel Syndrome.
Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2017 |
Budgetary Impact of Telotristat Ethyl, a Novel Treatment for Patients with Carcinoid Syndrome Diarrhea: A US Health Plan Perspective.
Topics: Antidiarrheals; Budgets; Diarrhea; Health Care Costs; Humans; Insurance, Health; Malignant Carcinoid Syndrome; Models, Economic; Phenylalanine; Pyrimidines; Somatostatin; United States | 2017 |
Telotristat ethyl: a novel agent for the therapy of carcinoid syndrome diarrhea.
Topics: Diarrhea; Humans; Malignant Carcinoid Syndrome; Phenylalanine; Prevalence; Pyrimidines; Quality of Life; Somatostatin; Treatment Outcome; Tryptophan Hydroxylase | 2018 |
Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators.
Topics: Analgesics, Opioid; Animals; CHO Cells; Constipation; Cricetulus; Diarrhea; Drug Partial Agonism; Gastrointestinal Agents; Gastrointestinal Transit; Imidazoles; Methylation; Mice; Molecular Docking Simulation; Morphine; Naltrexone; Narcotic Antagonists; Nociception; Phenylalanine; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2018 |
The impact of treatment with eluxadoline on health-related quality of life among adult patients with irritable bowel syndrome with diarrhea.
Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Quality of Life; Surveys and Questionnaires | 2019 |
Alosetron versus traditional pharmacotherapy in clinical practice: effects on resource use, health-related quality of life, safety and symptom improvement in women with severe diarrhea-predominant irritable bowel syndrome.
Topics: Adult; Aged; Carbolines; Diarrhea; Female; Health Resources; Humans; Imidazoles; Irritable Bowel Syndrome; Middle Aged; Phenylalanine; Quality of Life; Rifaximin | 2019 |
Long-Term Safety Experience with Telotristat Ethyl Across Five Clinical Studies in Patients with Carcinoid Syndrome.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Female; Humans; Male; Malignant Carcinoid Syndrome; Middle Aged; Patient Safety; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome | 2019 |
Safety of Eluxadoline Use.
Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2019 |
Response to Lai.
Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine | 2019 |
Item-level assessment of the irritable bowel syndrome quality of life questionnaire in patients with diarrheal irritable bowel syndrome.
Topics: Clinical Trials, Phase II as Topic; Diarrhea; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Models, Psychological; Phenylalanine; Psychometrics; Quality of Life; Surveys and Questionnaires | 2014 |
Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers.
Topics: Animals; Arrestins; beta-Arrestins; Castor Oil; Diarrhea; Humans; Imidazoles; Ligands; Loperamide; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Phenylalanine; Protein Multimerization; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction | 2014 |
Eluxadoline approved for irritable bowel syndrome with diarrhea.
Topics: Constipation; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; United States; United States Food and Drug Administration | 2015 |
Eluxadoline (Viberzi) for irritable bowel syndrome with diarrhea.
Topics: Administration, Oral; Adult; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, mu; United States; United States Food and Drug Administration | 2016 |
Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome.
Topics: Diabetes Mellitus, Type 1; Diarrhea; Dimerization; Eczema; Eosinophilia; Fatal Outcome; Forkhead Transcription Factors; Genetic Diseases, X-Linked; Growth Disorders; Hemorrhage; Hepatomegaly; Humans; Hydrophobic and Hydrophilic Interactions; Immune System Diseases; Immunoglobulin E; Infant; Klebsiella Infections; Leukocytosis; Lung Diseases; Male; Meningoencephalitis; Models, Molecular; Mutation; Phenylalanine; Sepsis; Splenomegaly; Thrombocytopenia; Thymus Gland | 2016 |
IBS: Treating IBS with diarrhoea.
Topics: Diarrhea; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Phenylalanine | 2016 |
Board Review Vignette: Irritable Bowel Syndrome.
Topics: Abdominal Pain; Adult; Anion Exchange Resins; Antidiarrheals; Carbolines; Cholestyramine Resin; Constipation; Diarrhea; Disease Management; Female; Gastrointestinal Agents; Guanylyl Cyclase C Agonists; Humans; Imidazoles; Irritable Bowel Syndrome; Laxatives; Loperamide; Peptides; Phenylalanine; Probiotics; Rifamycins; Rifaximin; Selective Serotonin Reuptake Inhibitors | 2016 |
Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea.
Topics: Administration, Oral; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Double-Blind Method; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Placebos; Randomized Controlled Trials as Topic; Single-Blind Method; Substance-Related Disorders | 2017 |
[Preventive action of phenylalanine on acute intoxication of ochratoxin-A].
Topics: Animals; Diarrhea; Dose-Response Relationship, Drug; Drug Antagonism; Mice; Ochratoxins; Phenylalanine | 1979 |
The effect of diarrhea on the oxidation of 14C-phenylalanine in piglets receiving diets varying in protein and proline concentration.
Topics: Animals; Animals, Suckling; Carbon Radioisotopes; Diarrhea; Dietary Proteins; Male; Oxidation-Reduction; Phenylalanine; Proline; Swine; Swine Diseases | 1986 |
Serotonin now: clinical implications of inhibiting its synthesis with para-chlorophenylalanine.
Topics: Adult; Aged; Animals; Behavior; Brain Chemistry; Catechols; Cattle; Depression; Diarrhea; Dogs; Enzyme Precursors; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Rabbits; Rats; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Sleep, REM; Testosterone; Tryptophan; Vasomotor System | 1970 |
Gas chromatographic analysis of urinary tyrosine and phenylalanine metabolites in patients with gastrointestinal disorders.
Topics: Acrylates; Adult; Bacteria; Benzene Derivatives; Benzoates; Celiac Disease; Child, Preschool; Chromatography, Gas; Cystic Fibrosis; Diarrhea; Diet; Diet Therapy; Enteritis; Gastrointestinal Diseases; Glutens; Humans; Hydroxylation; Infant; Intestine, Small; Intestines; Malabsorption Syndromes; Pancreatin; Phenylacetates; Phenylalanine; Propionates; Time Factors | 1971 |
Quantitative determination of intestinal peptide hydrolase activity using L-amino acid oxidase.
Topics: Amino Acid Oxidoreductases; Animals; Celiac Disease; Child; Diarrhea; Dipeptides; Glycoside Hydrolases; Guinea Pigs; Humans; Intestinal Mucosa; Intestines; Isoleucine; Kinetics; Lactose; Leucine; Mathematics; Methionine; Peptide Hydrolases; Peroxidases; Phenylalanine; Proline; Spectrophotometry | 1971 |
Serum alkaline phosphatase activity in cattle.
Topics: Abomasum; Aging; Alkaline Phosphatase; Animals; Bone and Bones; Brain; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Deficiency Diseases; Diarrhea; Duodenum; Female; Hydrogen-Ion Concentration; Isoenzymes; Kidney; Kinetics; Liver; Lung; Mammary Glands, Animal; Nitrophenols; Phenolphthaleins; Phenols; Phenylalanine; Phosphoric Acids; Placenta; Rumen; Spleen; Urea | 1971 |
The carcinoid syndrome: chronic treatment with para-chlorophenylalanine.
Topics: Amino Acids; Chlorine; Diarrhea; Dopamine; Heart Valve Diseases; Hepatomegaly; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Neoplasm Metastasis; Phenylalanine | 1970 |
Hypothermia in a patient with carcinoid syndrome during treatment with parachlorophenylalanine.
Topics: Body Temperature Regulation; Chlorine; Diarrhea; Humans; Hypothermia; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Serotonin | 1971 |