phenylalanine and Diarrhea

phenylalanine has been researched along with Diarrhea in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199010 (13.16)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's56 (73.68)24.3611
2020's10 (13.16)2.80

Authors

AuthorsStudies
Shah, ED1
Boinpally, R; Breen-Lyles, M; Busciglio, I; Camilleri, M; Carrothers, TJ; Maselli, D; Muslin, A; Nord, SL; Vijayvargiya, P1
Friedenberg, FK; Piech, G; Reichenbach, ZW; Selby, A1
Brenner, DM; Sayuk, GS1
Black, CJ; Ford, AC; Houghton, LA1
Andrae, DA; Covington, PS; Dove, LS; Lembo, AJ1
Brenner, DM; Cash, BD; Elmes, SJR; Gutman, CR; Jo, E; Liu, LWC; Sayuk, GS2
Benson, AB; Dharba, S; Joish, VN; Lapuerta, P; Sapre, D; Strosberg, J1
Liu, R; Staller, K1
Heidelbaugh, J; Jones, J; Kuritzky, L; Lacy, B; Lembo, A1
Abel, JL; Brenner, DM; Burslem, K; Sayuk, GS1
Andrae, DA; Chey, WD; Covington, PS; Dove, LS1
Markham, A1
Cash, BD; Chey, WD; Covington, PS; Dove, LS; Lacy, BE; Lembo, AJ1
Keating, GM1
Kulke, MH1
Júdez, FJ; Vera, I1
Frech, F; Joish, VN; Lapuerta, P2
Barkin, JS; Croteau, R1
Özdener, AE; Rivkin, A1
Masab, M; Saif, MW1
Anthony, L; Arnold, K; Bergsland, E; Caplin, M; DiBenedetti, DB; Ervin, C; Evans, E; Hörsch, D; Jackson, S; Kulke, MH; Kunz, P; Lapuerta, P; Law, L; Metz, DC; Öberg, K; Pasieka, J; Pavel, M; Pavlakis, N; Ramage, J; Yang, QM1
Anthony, LB; Benavent, M; Fleming, D; Fleming, R; Garcia-Carbonero, R; Gross, DJ; Hörsch, D; Jiang, W; Kassler-Taub, K; Kulke, MH; Kunz, PL; Lapuerta, P; Pavel, M; Perros, P; Srirajaskanthan, R; Warner, RRP; Wason, S; Weickert, MO1
Chandrasekharan, C; Dillon, JS1
Barbara, G; Barbaro, MR; De Ponti, F; Dothel, G; Raschi, E1
Anthony, LB; Bergsland, E; Caplin, ME; Grande, E; Hörsch, D; Kaltsas, G; Kittur, A; Kulke, MH; Kunz, PL; Lapuerta, P; Lombard-Bohas, C; Öberg, K; Pavel, M; Ramage, JK; Valle, JW; Weickert, MO; Welin, S; Yang, QM1
Lyseng-Williamson, KA1
Akbarali, HI; Dewey, WL; Komla, E; Obeng, S; Selley, DE; Stevens, DL; Wang, H; Zhang, Y; Zheng, Y1
Kasi, PM1
Corsetti, M; Pannemans, J1
Abel, JL; Andrae, DA; Carson, RT1
Chey, WD; Chuang, E; Earnest, DL; Olden, KW; Paul Nicandro, J; Shringarpure, R1
Beaumont, JL; Cella, D; Feuilly, M; Hörsch, D; Houchard, A; Hudgens, S; Kulke, MH; Lapuerta, P; Marteau, F; Pavel, M; Ramage, J1
Anthony, LB; Bergsland, E; Caplin, ME; Dillon, JS; Hörsch, D; Jiang, W; Kassler-Taub, K; Kulke, MH; Lapuerta, P; O'Dorisio, TM; Öberg, K; Pavel, M; Warner, RRP1
Gunn, D; Major, GAD1
Lai, SW1
Benson, AB; Dharba, S; Fish-Steagall, A; Giacalone, S; Joish, VN; Kapoor, K; Lapuerta, P; Perez-Olle, R; Strosberg, J1
Cash, BD; Covington, PS; Dove, LS; Lacy, BE; Schoenfeld, PS2
Almenoff, JS; Andrae, D; Covington, PS; Davenport, JM; Dove, LS; Fogel, R; Lembo, A; McIntyre, G; Randall, CW1
Andrae, DA; Covington, PS; Patrick, DL1
Banks, P; Bergsland, E; Fleming, D; Frazier, K; Freiman, J; Jackson, J; Kulke, MH; Kvols, L; Lapuerta, P; Law, L; O'Dorisio, T; Phan, A; Sands, A; Yao, JC; Zambrowicz, B1
Devi, LA; Dove, LS; Fujita, W; Gomes, I; McIntyre, G; Prohaska, D1
Traynor, K1
Garnock-Jones, KP1
Lembo, AJ; Nee, J; Zakari, M1
Cash, BD; Earnest, DL; Lacy, BE; Rao, T1
Lacy, BE1
Álvarez de la Campa, E; Colobran, R; de la Cruz, X; Martín-Nalda, A; Martínez-Gallo, M; Pujol-Borrell, R; Soler-Palacín, P1
Andrae, DA; Covington, PS; Davenport, JM; Dove, LS; Lacy, BE; Lembo, AJ; Lopez, R; McIntyre, G; Schey, R; Turner, L; Zuckerman, MJ1
Dickson, I1
Rivkin, A; Rybalov, S1
Storr, M1
Auguste, P; Boehm, KA; Gelhorn, HL; Jackson, J; Jackson, S; Kostelec, J; Kulke, MH; Lapuerta, P; Law, L; O'Dorisio, T; Yang, QM1
Abenavoli, L; Gasbarrini, A; Ianiro, G; Laterza, L; Scarpellini, E; Tack, J1
Lacy, BE; Moreau, JC1
Talley, NJ1
Weber, HC1
Anthony, LB; Banks, P; Bergsland, E; Caplin, ME; Fleming, D; Grande, E; Hörsch, D; Jackson, S; Kulke, MH; Kunz, PL; Lapuerta, P; Lombard-Bohas, C; Öberg, K; Pavel, M; Sands, AT; Valle, JW; Warner, RR; Welin, S; Zambrowicz, B1
Cash, BD; Covington, PS; Dove, LS; Fant, RV; Henningfield, JE1
Camilleri, M1
Creppy, E; Dirheimer, G; Röschenthaler, R; Schlegel, M1
Ball, RO; Bayley, HS1
Grahame-Smith, DG1
Duran, M; Ketting, D; van der Heiden, C; Wadman, SK; Wauters, EA1
Donlon, J; Fottrell, PF1
Healy, PJ1
Bianchine, JR; Satterlee, WG; Serpick, A1
Levine, RJ; Vaidya, AB1

Reviews

23 review(s) available for phenylalanine and Diarrhea

ArticleYear
Pathophysiology, Differential Diagnosis, and Treatment of Diabetic Diarrhea.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Antidiarrheals; Autonomic Nervous System Diseases; Blind Loop Syndrome; Celiac Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Diarrhea; Diphenoxylate; Enteric Nervous System; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Inflammation; Inflammatory Bowel Diseases; Interstitial Cells of Cajal; Intestinal Absorption; Intestinal Mucosa; Irritable Bowel Syndrome; Loperamide; Neuroglia; Non-Nutritive Sweeteners; Oxidative Stress; Phenylalanine; Serotonin 5-HT3 Receptor Antagonists

2019
Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea.
    Advances in therapy, 2020, Volume: 37, Issue:1

    Topics: Adult; Carbolines; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life; Rifaximin; United States; United States Food and Drug Administration

2020
Update on Eluxadoline for the Treatment of Irritable Bowel Syndrome with Diarrhea: Patient Selection and Perspectives.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Patient Selection; Phenylalanine

2020
Eluxadoline: A Review in Diarrhoea-Predominant Irritable Bowel Syndrome.
    Drugs, 2017, Volume: 77, Issue:9

    Topics: Adult; Constipation; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Opioid, delta

2017
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome. The SEPD perspective.
    Revista espanola de enfermedades digestivas, 2017, Volume: 109, Issue:11

    Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life; Randomized Controlled Trials as Topic

2017
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Clinical Trials as Topic; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2017
Telotristat ethyl: proof of principle and the first oral agent in the management of well-differentiated metastatic neuroendocrine tumor and carcinoid syndrome diarrhea.
    Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:6

    Topics: Administration, Oral; Diarrhea; Female; Humans; Male; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines

2017
Advancements in drug development for diarrhea-predominant irritable bowel syndrome.
    Expert opinion on investigational drugs, 2018, Volume: 27, Issue:3

    Topics: Animals; Benzimidazoles; Diarrhea; Drug and Narcotic Control; Drug Design; Gastrointestinal Agents; Humans; Imidazoles; Internationality; Irritable Bowel Syndrome; Phenylalanine

2018
Telotristat Ethyl: A Review in Carcinoid Syndrome Diarrhoea.
    Drugs, 2018, Volume: 78, Issue:9

    Topics: Diarrhea; Drug Interactions; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Signal Transduction; Somatostatin; Treatment Outcome; Tryptophan Hydroxylase

2018
Telotristat ethyl for the treatment of carcinoid syndrome diarrhea not controlled by somatostatin analogues.
    Drugs of today (Barcelona, Spain : 1998), 2018, Volume: 54, Issue:7

    Topics: Clinical Trials as Topic; Diarrhea; Humans; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Somatostatin

2018
Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders?
    Current opinion in pharmacology, 2018, Volume: 43

    Topics: Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Defecation; Diarrhea; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Imidazoles; Inflammatory Bowel Diseases; Laxatives; Morphinans; Naltrexone; Narcotic Antagonists; Phenylalanine; Polyethylene Glycols; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Signal Transduction

2018
Chronic diarrhoea in adults: what not to miss.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Adenocarcinoma; Adenoma; Antidiarrheals; Bile Acids and Salts; Celiac Disease; Chronic Disease; Colorectal Neoplasms; Diarrhea; Exocrine Pancreatic Insufficiency; Feces; Gastrointestinal Agents; Humans; Iatrogenic Disease; Imidazoles; Immunochemistry; Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Leukocyte L1 Antigen Complex; Loperamide; Malabsorption Syndromes; Phenylalanine; Steatorrhea

2019
Eluxadoline: First Global Approval.
    Drugs, 2015, Volume: 75, Issue:11

    Topics: Adult; Animals; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu

2015
Current and emerging drug options in the treatment of diarrhea predominant irritable bowel syndrome.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:18

    Topics: Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine; Receptors, Opioid; Rifamycins; Rifaximin

2015
Rifaximin and eluxadoline - newly approved treatments for diarrhea-predominant irritable bowel syndrome: what is their role in clinical practice alongside alosetron?
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:3

    Topics: Abdominal Pain; Anti-Bacterial Agents; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Narcotic Antagonists; Phenylalanine; Receptors, Opioid; Rifamycins; Rifaximin; Serotonin 5-HT3 Receptor Antagonists

2016
Emerging treatments in neurogastroenterology: eluxadoline - a new therapeutic option for diarrhea-predominant IBS.
    Neurogastroenterology and motility, 2016, Volume: 28, Issue:1

    Topics: Antidiarrheals; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Pancreatitis; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2016
Update on the Management of Diarrhea-Predominant Irritable Bowel Syndrome: Focus on Rifaximin and Eluxadoline.
    Pharmacotherapy, 2016, Volume: 36, Issue:3

    Topics: Administration, Oral; Diarrhea; Disease Management; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin

2016
Eluxadoline for the treatment of diarrhoea-predominant irritable bowel syndrome.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:10

    Topics: Abdominal Pain; Constipation; Diarrhea; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid

2016
Diarrhea-predominant irritable bowel syndrome: Diagnosis, etiology, and new treatment considerations.
    Journal of the American Association of Nurse Practitioners, 2016, Volume: 28, Issue:7

    Topics: Carbolines; Diarrhea; Disease Management; Humans; Imidazoles; Irritable Bowel Syndrome; Parasympatholytics; Phenylalanine; Rifamycins; Rifaximin; United States

2016
New treatment options for irritable bowel syndrome with predominant diarrhea.
    Current opinion in endocrinology, diabetes, and obesity, 2017, Volume: 24, Issue:1

    Topics: Anti-Bacterial Agents; Constipation; Diarrhea; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Narcotic Antagonists; Phenylalanine; Quality of Life; Receptors, Opioid; Rifamycins; Rifaximin

2017
LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:3

    Topics: Animals; Biphenyl Compounds; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Phenylalanine; Receptors, Serotonin; Serotonin; Tryptophan Hydroxylase

2011
Pharmacology of the carcinoid syndrome.
    Lancet (London, England), 1968, Feb-24, Volume: 1, Issue:7539

    Topics: 5-Hydroxytryptophan; Bradykinin; Diarrhea; Drug Synergism; Humans; Kinins; Malignant Carcinoid Syndrome; Methysergide; Neurologic Manifestations; Phenylalanine; Prostaglandins; Serotonin; Serotonin Antagonists; Skin Manifestations

1968
Progress report: the carcinoid syndrome.
    Gut, 1970, Volume: 11, Issue:2

    Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydroxyindoleacetic Acid; Kallikreins; Liver Neoplasms; Malignant Carcinoid Syndrome; Methyldopa; Methysergide; Neoplasm Metastasis; Phenoxybenzamine; Phenylalanine; Serotonin

1970

Trials

16 trial(s) available for phenylalanine and Diarrhea

ArticleYear
Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials.
    Neurogastroenterology and motility, 2020, Volume: 32, Issue:4

    Topics: Abdominal Pain; Adult; Aged; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Treatment Outcome

2020
Early response predicts a sustained response to eluxadoline in patients with irritable bowel syndrome with diarrhoea in two Phase 3 studies.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:10

    Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Prognosis; Retrospective Studies; Time Factors

2017
Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:6

    Topics: Abdominal Pain; Adult; Antidiarrheals; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Pain Measurement; Phenylalanine; Symptom Assessment

2017
Understanding the Patient Experience with Carcinoid Syndrome: Exit Interviews from a Randomized, Placebo-controlled Study of Telotristat Ethyl.
    Clinical therapeutics, 2017, Volume: 39, Issue:11

    Topics: Diarrhea; Double-Blind Method; Female; Humans; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome

2017
Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial.
    Endocrine-related cancer, 2018, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Diarrhea; Double-Blind Method; Female; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Somatostatin; Treatment Outcome

2018
Changes in Weight Associated With Telotristat Ethyl in the Treatment of Carcinoid Syndrome.
    Clinical therapeutics, 2018, Volume: 40, Issue:6

    Topics: Aged; Body Weight; Diarrhea; Double-Blind Method; Female; Humans; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome; Tryptophan Hydroxylase

2018
Relationship Between Symptoms and Health-related Quality-of-life Benefits in Patients With Carcinoid Syndrome: Post Hoc Analyses From TELESTAR.
    Clinical therapeutics, 2018, Volume: 40, Issue:12

    Topics: Aged; Diarrhea; Double-Blind Method; Female; Humans; Male; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Quality of Life; Treatment Outcome; Tryptophan Hydroxylase

2018
TELEPRO: Patient-Reported Carcinoid Syndrome Symptom Improvement Following Initiation of Telotristat Ethyl in the Real World.
    The oncologist, 2019, Volume: 24, Issue:11

    Topics: Aged; Cohort Studies; Diarrhea; Female; Follow-Up Studies; Humans; International Agencies; Male; Malignant Carcinoid Syndrome; Patient Reported Outcome Measures; Phenylalanine; Prognosis; Pyrimidines

2019
Efficacy and Safety of Eluxadoline in Patients With Irritable Bowel Syndrome With Diarrhea Who Report Inadequate Symptom Control With Loperamide: RELIEF Phase 4 Study.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Phenylalanine; Prospective Studies

2019
Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study.
    Gastroenterology, 2013, Volume: 145, Issue:2

    Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Treatment Outcome

2013
Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
    Endocrine-related cancer, 2014, Volume: 21, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Diarrhea; Female; Gastrointestinal Agents; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Octreotide; Phenylalanine; Pyrimidines; Serotonin Antagonists; Treatment Outcome

2014
Eluxadoline for Irritable Bowel Syndrome with Diarrhea.
    The New England journal of medicine, 2016, Jan-21, Volume: 374, Issue:3

    Topics: Abdominal Pain; Adult; Aged; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Pancreatitis; Phenylalanine

2016
[A new remedy for diarrheal irritable bowel syndrome].
    MMW Fortschritte der Medizin, 2016, Mar-17, Volume: 158, Issue:5

    Topics: Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; United States

2016
Patient-reported Symptom Experiences in Patients With Carcinoid Syndrome After Participation in a Study of Telotristat Etiprate: A Qualitative Interview Approach.
    Clinical therapeutics, 2016, Volume: 38, Issue:4

    Topics: Aged; Antineoplastic Agents; Diarrhea; Female; Humans; Interviews as Topic; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome

2016
Telotristat Ethyl, a Tryptophan Hydroxylase Inhibitor for the Treatment of Carcinoid Syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Volume: 35, Issue:1

    Topics: Aged; Antineoplastic Agents, Hormonal; Defecation; Diarrhea; Double-Blind Method; Female; gamma-Glutamyltransferase; Gastrointestinal Agents; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Nausea; Octreotide; Peptides, Cyclic; Phenylalanine; Pyrimidines; Somatostatin; Tryptophan Hydroxylase

2017
Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:2

    Topics: Abdominal Pain; Adult; Aged; Constipation; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Nausea; Pancreatitis; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spasm; Sphincter of Oddi Dysfunction

2017

Other Studies

37 other study(ies) available for phenylalanine and Diarrhea

ArticleYear
Delta Variant: Expanding the Indication for Eluxadoline to Bile Acid Diarrhea.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:8

    Topics: Bile Acids and Salts; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2022
Safety and Efficacy of Eluxadoline in Patients with Irritable Bowel Syndrome-Diarrhea With or Without Bile Acid Diarrhea: Open-Label Study.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:8

    Topics: Adult; Bile Acids and Salts; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life

2022
Efficacy of Eluxadoline in Irritable Bowel Syndrome With Diarrhea.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:3

    Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine

2020
Response to Black et al.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:3

    Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine

2020
Clinical Benefits of Telotristat Ethyl in Patients With Neuroendocrine Tumors and Low Bowel Movement Frequency: An Observational Patient-Reported Outcomes Study.
    Pancreas, 2020, Volume: 49, Issue:3

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Child; Child, Preschool; Defecation; Diarrhea; Female; Flushing; Humans; Infant; Infant, Newborn; Male; Malignant Carcinoid Syndrome; Middle Aged; Nausea; Patient Reported Outcome Measures; Phenylalanine; Pyrimidines; Recovery of Function; Time Factors; Treatment Outcome; Young Adult

2020
Management of irritable bowel syndrome with diarrhea: focus on eluxadoline.
    Current medical research and opinion, 2021, Volume: 37, Issue:4

    Topics: Adult; Aged; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2021
Improved work productivity and health-related quality of life in patients with irritable bowel syndrome with diarrhea receiving eluxadoline following inadequate response to loperamide.
    Journal of managed care & specialty pharmacy, 2021, Volume: 27, Issue:4

    Topics: Absenteeism; Adolescent; Adult; Aged; Aged, 80 and over; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Phenylalanine; Quality of Life; Surveys and Questionnaires; United States; Young Adult

2021
Telotristat Ethyl: First Global Approval.
    Drugs, 2017, Volume: 77, Issue:7

    Topics: Animals; Diarrhea; Drug Approval; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Somatostatin; Tryptophan Hydroxylase; United States; United States Food and Drug Administration

2017
Advances in the management of patients with carcinoid syndrome.
    Clinical advances in hematology & oncology : H&O, 2017, Volume: 15, Issue:4

    Topics: Carcinoid Tumor; Clinical Trials, Phase III as Topic; Diarrhea; Humans; Malignant Carcinoid Syndrome; Phenylalanine; Pyrimidines

2017
Telotristat ethyl (Xermelo) for carcinoid syndrome diarrhea.
    The Medical letter on drugs and therapeutics, 2017, 07-17, Volume: 59, Issue:1525

    Topics: Antidiarrheals; Diarrhea; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Octreotide; Phenylalanine; Pyrimidines; Treatment Outcome

2017
Τ Eluxadoline for IBS-D.
    Drug and therapeutics bulletin, 2017, Volume: 55, Issue:8

    Topics: Contraindications, Drug; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2017
Cost-effectiveness analysis of telotristat ethyl for treatment of carcinoid syndrome diarrhea inadequately controlled with somatostatin analogs.
    Journal of medical economics, 2018, Volume: 21, Issue:2

    Topics: Adult; Aged; Cost-Benefit Analysis; Diarrhea; Drug Costs; Drug Therapy, Combination; Female; Health Resources; Humans; Male; Malignant Carcinoid Syndrome; Markov Chains; Middle Aged; Phenylalanine; Pyrimidines; Quality-Adjusted Life Years; Somatostatin; Treatment Outcome; United States

2018
Safety of Eluxadoline in Patients With Irritable Bowel Syndrome.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:10

    Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2017
Budgetary Impact of Telotristat Ethyl, a Novel Treatment for Patients with Carcinoid Syndrome Diarrhea: A US Health Plan Perspective.
    Clinical therapeutics, 2017, Volume: 39, Issue:12

    Topics: Antidiarrheals; Budgets; Diarrhea; Health Care Costs; Humans; Insurance, Health; Malignant Carcinoid Syndrome; Models, Economic; Phenylalanine; Pyrimidines; Somatostatin; United States

2017
Telotristat ethyl: a novel agent for the therapy of carcinoid syndrome diarrhea.
    Future oncology (London, England), 2018, Volume: 14, Issue:12

    Topics: Diarrhea; Humans; Malignant Carcinoid Syndrome; Phenylalanine; Prevalence; Pyrimidines; Quality of Life; Somatostatin; Treatment Outcome; Tryptophan Hydroxylase

2018
Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Analgesics, Opioid; Animals; CHO Cells; Constipation; Cricetulus; Diarrhea; Drug Partial Agonism; Gastrointestinal Agents; Gastrointestinal Transit; Imidazoles; Methylation; Mice; Molecular Docking Simulation; Morphine; Naltrexone; Narcotic Antagonists; Nociception; Phenylalanine; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2018
The impact of treatment with eluxadoline on health-related quality of life among adult patients with irritable bowel syndrome with diarrhea.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019, Volume: 28, Issue:2

    Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Quality of Life; Surveys and Questionnaires

2019
Alosetron versus traditional pharmacotherapy in clinical practice: effects on resource use, health-related quality of life, safety and symptom improvement in women with severe diarrhea-predominant irritable bowel syndrome.
    Current medical research and opinion, 2019, Volume: 35, Issue:3

    Topics: Adult; Aged; Carbolines; Diarrhea; Female; Health Resources; Humans; Imidazoles; Irritable Bowel Syndrome; Middle Aged; Phenylalanine; Quality of Life; Rifaximin

2019
Long-Term Safety Experience with Telotristat Ethyl Across Five Clinical Studies in Patients with Carcinoid Syndrome.
    The oncologist, 2019, Volume: 24, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Female; Humans; Male; Malignant Carcinoid Syndrome; Middle Aged; Patient Safety; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome

2019
Safety of Eluxadoline Use.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:7

    Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2019
Response to Lai.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:7

    Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine

2019
Item-level assessment of the irritable bowel syndrome quality of life questionnaire in patients with diarrheal irritable bowel syndrome.
    Clinical therapeutics, 2014, Volume: 36, Issue:5

    Topics: Clinical Trials, Phase II as Topic; Diarrhea; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Models, Psychological; Phenylalanine; Psychometrics; Quality of Life; Surveys and Questionnaires

2014
Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers.
    Biochemical pharmacology, 2014, Dec-01, Volume: 92, Issue:3

    Topics: Animals; Arrestins; beta-Arrestins; Castor Oil; Diarrhea; Humans; Imidazoles; Ligands; Loperamide; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Phenylalanine; Protein Multimerization; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction

2014
Eluxadoline approved for irritable bowel syndrome with diarrhea.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Jul-01, Volume: 72, Issue:13

    Topics: Constipation; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; United States; United States Food and Drug Administration

2015
Eluxadoline (Viberzi) for irritable bowel syndrome with diarrhea.
    The Medical letter on drugs and therapeutics, 2016, Jan-04, Volume: 58, Issue:1485

    Topics: Administration, Oral; Adult; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, mu; United States; United States Food and Drug Administration

2016
Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome.
    Clinical immunology (Orlando, Fla.), 2016, Volume: 163

    Topics: Diabetes Mellitus, Type 1; Diarrhea; Dimerization; Eczema; Eosinophilia; Fatal Outcome; Forkhead Transcription Factors; Genetic Diseases, X-Linked; Growth Disorders; Hemorrhage; Hepatomegaly; Humans; Hydrophobic and Hydrophilic Interactions; Immune System Diseases; Immunoglobulin E; Infant; Klebsiella Infections; Leukocytosis; Lung Diseases; Male; Meningoencephalitis; Models, Molecular; Mutation; Phenylalanine; Sepsis; Splenomegaly; Thrombocytopenia; Thymus Gland

2016
IBS: Treating IBS with diarrhoea.
    Nature reviews. Gastroenterology & hepatology, 2016, Volume: 13, Issue:3

    Topics: Diarrhea; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Phenylalanine

2016
Board Review Vignette: Irritable Bowel Syndrome.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:9

    Topics: Abdominal Pain; Adult; Anion Exchange Resins; Antidiarrheals; Carbolines; Cholestyramine Resin; Constipation; Diarrhea; Disease Management; Female; Gastrointestinal Agents; Guanylyl Cyclase C Agonists; Humans; Imidazoles; Irritable Bowel Syndrome; Laxatives; Loperamide; Peptides; Phenylalanine; Probiotics; Rifamycins; Rifaximin; Selective Serotonin Reuptake Inhibitors

2016
Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017, Volume: 15, Issue:7

    Topics: Administration, Oral; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Double-Blind Method; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Placebos; Randomized Controlled Trials as Topic; Single-Blind Method; Substance-Related Disorders

2017
[Preventive action of phenylalanine on acute intoxication of ochratoxin-A].
    Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles, 1979, Nov-19, Volume: 289, Issue:13

    Topics: Animals; Diarrhea; Dose-Response Relationship, Drug; Drug Antagonism; Mice; Ochratoxins; Phenylalanine

1979
The effect of diarrhea on the oxidation of 14C-phenylalanine in piglets receiving diets varying in protein and proline concentration.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1986, Volume: 50, Issue:3

    Topics: Animals; Animals, Suckling; Carbon Radioisotopes; Diarrhea; Dietary Proteins; Male; Oxidation-Reduction; Phenylalanine; Proline; Swine; Swine Diseases

1986
Serotonin now: clinical implications of inhibiting its synthesis with para-chlorophenylalanine.
    Annals of internal medicine, 1970, Volume: 73, Issue:4

    Topics: Adult; Aged; Animals; Behavior; Brain Chemistry; Catechols; Cattle; Depression; Diarrhea; Dogs; Enzyme Precursors; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Rabbits; Rats; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Sleep, REM; Testosterone; Tryptophan; Vasomotor System

1970
Gas chromatographic analysis of urinary tyrosine and phenylalanine metabolites in patients with gastrointestinal disorders.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 34, Issue:2

    Topics: Acrylates; Adult; Bacteria; Benzene Derivatives; Benzoates; Celiac Disease; Child, Preschool; Chromatography, Gas; Cystic Fibrosis; Diarrhea; Diet; Diet Therapy; Enteritis; Gastrointestinal Diseases; Glutens; Humans; Hydroxylation; Infant; Intestine, Small; Intestines; Malabsorption Syndromes; Pancreatin; Phenylacetates; Phenylalanine; Propionates; Time Factors

1971
Quantitative determination of intestinal peptide hydrolase activity using L-amino acid oxidase.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Celiac Disease; Child; Diarrhea; Dipeptides; Glycoside Hydrolases; Guinea Pigs; Humans; Intestinal Mucosa; Intestines; Isoleucine; Kinetics; Lactose; Leucine; Mathematics; Methionine; Peptide Hydrolases; Peroxidases; Phenylalanine; Proline; Spectrophotometry

1971
Serum alkaline phosphatase activity in cattle.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:2

    Topics: Abomasum; Aging; Alkaline Phosphatase; Animals; Bone and Bones; Brain; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Deficiency Diseases; Diarrhea; Duodenum; Female; Hydrogen-Ion Concentration; Isoenzymes; Kidney; Kinetics; Liver; Lung; Mammary Glands, Animal; Nitrophenols; Phenolphthaleins; Phenols; Phenylalanine; Phosphoric Acids; Placenta; Rumen; Spleen; Urea

1971
The carcinoid syndrome: chronic treatment with para-chlorophenylalanine.
    Annals of internal medicine, 1970, Volume: 72, Issue:6

    Topics: Amino Acids; Chlorine; Diarrhea; Dopamine; Heart Valve Diseases; Hepatomegaly; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Neoplasm Metastasis; Phenylalanine

1970
Hypothermia in a patient with carcinoid syndrome during treatment with parachlorophenylalanine.
    The New England journal of medicine, 1971, Feb-04, Volume: 284, Issue:5

    Topics: Body Temperature Regulation; Chlorine; Diarrhea; Humans; Hypothermia; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Serotonin

1971