phenylalanine and Cognition Disorders

phenylalanine has been researched along with Cognition Disorders in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (19.35)	18.2507
2000's	10 (32.26)	29.6817
2010's	15 (48.39)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Abeling, NGGM; Bakermans, AJ; Bassett, AS; Booij, J; Boot, E; Bosch, AM; Bour, LJ; Hollak, CEM; Huijbregts, SCJ; Jahja, R; Nederveen, AJ; Nieman, DH; van Amelsvoort, TAMJ; van Spronsen, FJ; van Vliet, D	1
Champ, CL; Dye, L; Henderson, M; Hofman, DL; Lawton, CL	1
Feldmann, R; Fromm, J; Onon, S; Osterloh, J; Rutsch, F; Weglage, J	1
Fuchs, D; Geisler, S; Leblhuber, F; Wissmann, P	1
Araujo, GC; Christ, SE; Coleman, C; Grange, DK; Steiner, RD; Timmerman, E; White, DA	1
Frölich, L; Hartmann, T; Hausner, L; Hentschel, F; Schmitt, HP; Tschäpe, JA	1
Soloway, AH; Soloway, PD; Warner, VD	1
Geberhiwot, T; Hall, SK; Limback, E; MacDonald, A; Palermo, L; Romani, C	2
Araujo, GC; Christ, SE; Grange, DK; McKinstry, RC; Nardos, B; Steiner, RD; White, DA	1
Benjamin, C; Berkovic, SF; Fedi, M; Reutens, DC; Saling, MM; Scheffer, IE; Wood, AG	1
McGill, J; Sharman, R; Sullivan, K; Young, R	1
Benkelfat, C; Coderre, E; Dumas, J; Naylor, M; Newhouse, PA; Sites, CK; Wilkins, H; Young, SN	1
Bélanger-Quintana, A; Blau, N; Demirkol, M; Feillet, F; Giovannini, M; MacDonald, A; Trefz, FK; van Spronsen, FJ	1
Carton, D; Dan, B; De Laet, C; François, B; Goyens, PJ; Jaeken, J; Munoz, VT; Sokal, EM	1
Biernacka, M; Biernacki, M; Jakubowska-Winecka, A; Kowalik, A; Kuśmierska, K; Pohorecka, M; Sykut-Cegielska, J	1
de Sonneville, L; Huijbregts, S; Licht, R; Sergeant, J; van Spronsen, F	1
Antshel, KM; Waisbren, SE	1
Cockburn, F; Lee, PJ; Ridout, D; Walter, JH	1
Azen, C; Broomand, C; Brumm, VL; Koch, R; Moats, RA; Nelson, MD; Stern, AM	1
Bamber, DJ; Blackwell, AD; Goodyer, I; Jones, PB; McLean, A; Ogilvie, AD; Roiser, JP; Sahakian, BJ	1
Arthur, M; Burnett, JR; Bynevelt, M; Fox, AM; Moyle, JJ	1
Albasanz, JL; Barrachina, M; Ferrer, I; Martín, M; Perez-Buira, S; Rodriguez, A	1
Diamond, A	1
de Sonneville, L; Kobialka, B; Kutscha, A; Matthis, P; Pietz, J; Schmidt, E	1
de Sonneville, L; Kutscha, A; Landwehr, R; Pietz, J; Schmidt, H; Trefz, FK	1
Griffiths, P; Robinson, P; Tarrini, M	1
Callender, G; Diamond, A; Druin, DP; Prevor, MB	1
Azen, C; de la Cruz, F; Friedman, EG; Güttler, F; Hanley, WB; Koch, R; Levy, HL; Matalon, R; Platt, LD; Rouse, B; Trefz, F	1
de Sonneville, LM; Huijbregts, SC; Licht, R; Sergeant, JA; van Spronsen, FJ; Verkerk, PH	1
McCabe, ER; Ozonoff, S; Pennington, BF; Rouse, B; Welsh, MC	1

Reviews

3 review(s) available for phenylalanine and Cognition Disorders

Article	Year
A systematic review of cognitive functioning in early treated adults with phenylketonuria. Orphanet journal of rare diseases, 2018, 08-30, Volume: 13, Issue:1 Topics: Attention; Cognition; Cognition Disorders; Female; Humans; Male; Phenylalanine; Phenylketonurias	2018
Meta-analysis of neuropsychological symptoms of adolescents and adults with PKU. Neuropsychology review, 2007, Volume: 17, Issue:2 Topics: Adolescent; Adult; Brain; Cognition Disorders; Humans; Intelligence; Neurologic Examination; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Psychomotor Disorders; Young Adult	2007
Phenylalanine levels of 6-10 mg/dl may not be as benign as once thought. Acta paediatrica (Oslo, Norway : 1992). Supplement, 1994, Volume: 407 Topics: Animals; Case-Control Studies; Cerebral Cortex; Cognition Disorders; Contrast Sensitivity; Cross-Sectional Studies; Disease Models, Animal; Humans; Longitudinal Studies; Phenylalanine; Phenylketonurias; Rats	1994

Trials

4 trial(s) available for phenylalanine and Cognition Disorders

Article	Year
Estrogen treatment impairs cognitive performance after psychosocial stress and monoamine depletion in postmenopausal women. Menopause (New York, N.Y.), 2010, Volume: 17, Issue:4 Topics: Affect; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Double-Blind Method; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Mental Recall; Middle Aged; Neuropsychological Tests; Phenylalanine; Postmenopause; Stress, Psychological; Tryptophan; Tyrosine	2010
Neuropsychological outcome of NTBC-treated patients with tyrosinaemia type 1. Developmental medicine and child neurology, 2011, Volume: 53, Issue:10 Topics: Adolescent; Belgium; Child; Child, Preschool; Cognition Disorders; Cyclohexanones; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Intelligence; Intelligence Tests; Male; Neuropsychological Tests; Nitrobenzoates; Phenylalanine; Treatment Outcome; Tyrosine; Tyrosinemias	2011
The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:4 Topics: Adult; Amino Acids, Neutral; Brain; Cognition Disorders; Cross-Over Studies; Decision Making; Depressive Disorder; Dopamine; Double-Blind Method; Female; Food, Formulated; Gambling; Humans; Judgment; Male; Middle Aged; Neuropsychological Tests; Phenylalanine; Recovery of Function; Reward; Tyrosine	2005
Effect of high-dose tyrosine supplementation on brain function in adults with phenylketonuria. The Journal of pediatrics, 1995, Volume: 127, Issue:6 Topics: Adolescent; Adult; Brain; Cognition Disorders; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials, Visual; Female; Humans; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Placebos; Psychological Tests; Reaction Time; Tyrosine	1995

Other Studies

24 other study(ies) available for phenylalanine and Cognition Disorders

Article	Year
Cerebral dopamine deficiency, plasma monoamine alterations and neurocognitive deficits in adults with phenylketonuria. Psychological medicine, 2017, Volume: 47, Issue:16 Topics: Adolescent; Adult; Biogenic Monoamines; Brain; Case-Control Studies; Cognition; Cognition Disorders; Dopamine; Executive Function; Female; Humans; Impulsive Behavior; Longitudinal Studies; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Receptors, Dopamine D2; Young Adult	2017
Neurocognitive functioning in adults with phenylketonuria: Report of a 10-year follow-up. Molecular genetics and metabolism, 2019, Volume: 126, Issue:3 Topics: Adult; Age Factors; Attention; Brain; Cognition; Cognition Disorders; Diet; Female; Follow-Up Studies; Humans; Intelligence; Longitudinal Studies; Male; Mental Status and Dementia Tests; Middle Aged; Neuropsychological Tests; Phenylalanine; Phenylketonurias	2019
Immune activation in patients with Alzheimer's disease is associated with high serum phenylalanine concentrations. Journal of the neurological sciences, 2013, Jun-15, Volume: 329, Issue:1-2 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Neuropsychological Tests; Phenylalanine; Psychiatric Status Rating Scales; Single-Blind Method; Statistics, Nonparametric; Tyrosine	2013
Executive response monitoring and inhibitory control in children with phenylketonuria: effects of expectancy. Developmental neuropsychology, 2013, Volume: 38, Issue:3 Topics: Adolescent; Age Factors; Child; Cognition Disorders; Decision Making; Executive Function; Female; Humans; Inhibition, Psychological; Intention; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Reaction Time; Regression Analysis	2013
Clinical characterization of a presenilin 1 mutation (F177S) in a family with very early-onset Alzheimer's disease in the third decade of life. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2014, Volume: 10, Issue:2 Topics: Adult; Age of Onset; Aged; Alzheimer Disease; Amyloid beta-Peptides; Brain; Brain Waves; Cognition Disorders; Electroencephalography; Family Health; Female; Genetic Predisposition to Disease; Humans; Male; Mental Status Schedule; Middle Aged; Mutation; Peptide Fragments; Phenylalanine; Positron-Emission Tomography; Presenilin-1; Radiography; Serine	2014
Possible chemical initiators of cognitive dysfunction in phenylketonuria, Parkinson's disease and Alzheimer's disease. Medical hypotheses, 2013, Volume: 81, Issue:4 Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methionine; Models, Biological; Molecular Structure; Oxidative Stress; Parkinson Disease; Phenylalanine; Phenylketonurias; Tyrosine	2013
Cognitive outcomes in early-treated adults with phenylketonuria (PKU): A comprehensive picture across domains. Neuropsychology, 2017, Volume: 31, Issue:3 Topics: Adult; Brain; Cognition; Cognition Disorders; Diet; Early Medical Intervention; Executive Function; Female; Humans; Male; Memory; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Treatment Outcome; Young Adult	2017
The impact of phenylalanine levels on cognitive outcomes in adults with phenylketonuria: Effects across tasks and developmental stages. Neuropsychology, 2017, Volume: 31, Issue:3 Topics: Adolescent; Adult; Attention; Brain; Cognition; Cognition Disorders; Executive Function; Female; Humans; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Young Adult	2017
Response monitoring in children with phenylketonuria. Neuropsychology, 2009, Volume: 23, Issue:1 Topics: Adolescent; Age Factors; Attention; Child; Cognition Disorders; Female; Humans; Inhibition, Psychological; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Psychomotor Performance; Reaction Time	2009
Neuropsychological function in patients with a single gene mutation associated with autosomal dominant nocturnal frontal lobe epilepsy. Epilepsy & behavior : E&B, 2010, Volume: 17, Issue:4 Topics: Adult; Association Learning; Circadian Rhythm; Cognition Disorders; Epilepsy, Frontal Lobe; Female; Frontal Lobe; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Mutation; Neuropsychological Tests; Pedigree; Phenylalanine; Polysomnography; Receptors, Nicotinic; Serine; Young Adult	2010
A preliminary investigation of the role of the phenylalanine:tyrosine ratio in children with early and continuously treated phenylketonuria: toward identification of "safe" levels. Developmental neuropsychology, 2010, Volume: 35, Issue:1 Topics: Adolescent; Analysis of Variance; Child; Cognition Disorders; Executive Function; Humans; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Severity of Illness Index; Surveys and Questionnaires; Tyrosine	2010
Challenges and pitfalls in the management of phenylketonuria. Pediatrics, 2010, Volume: 126, Issue:2 Topics: Biopterins; Brain; Cognition Disorders; Consensus; Growth Disorders; Humans; Infant, Newborn; Neonatal Screening; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Treatment Failure	2010
Behavioral and intellectual functioning in patients with tyrosinemia type I. Pediatric endocrinology, diabetes, and metabolism, 2012, Volume: 18, Issue:3 Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Mental Disorders; Phenylalanine; Problem Solving; Tyrosine; Tyrosinemias; Wechsler Scales	2012
Inhibition of prepotent responding and attentional flexibility in treated phenylketonuria. Developmental neuropsychology, 2002, Volume: 22, Issue:2 Topics: Adolescent; Attention; Case-Control Studies; Child; Cognition Disorders; Female; Humans; Inhibition, Psychological; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Psychomotor Performance	2002
Timing is everything: executive functions in children exposed to elevated levels of phenylalanine. Neuropsychology, 2003, Volume: 17, Issue:3 Topics: Adolescent; Age of Onset; Attention; Attention Deficit Disorder with Hyperactivity; Brain; Case-Control Studies; Child; Cognition Disorders; Female; Humans; Male; Memory; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Psychomotor Disorders; Time Factors; Verbal Learning	2003
Maternal phenylketonuria: report from the United Kingdom Registry 1978-97. Archives of disease in childhood, 2005, Volume: 90, Issue:2 Topics: Analysis of Variance; Birth Weight; Child; Child, Preschool; Cognition Disorders; Developmental Disabilities; Female; Head; Heart Defects, Congenital; Humans; Infant, Newborn; Intelligence; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Registries; Time Factors; United Kingdom	2005
Neuropsychological outcome of subjects participating in the PKU adult collaborative study: a preliminary review. Journal of inherited metabolic disease, 2004, Volume: 27, Issue:5 Topics: Adult; Brain; Cognition Disorders; Female; Frontal Lobe; Humans; Intelligence; Intelligence Tests; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Temporal Lobe	2004
Expression levels of adenosine receptors in hippocampus and frontal cortex in argyrophilic grain disease. Neuroscience letters, 2007, Aug-23, Volume: 423, Issue:3 Topics: Adenosine A1 Receptor Agonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Aged, 80 and over; Cadaver; Cognition Disorders; Colforsin; Dementia; Female; Frontal Lobe; Hippocampus; Humans; Male; Middle Aged; Phenylalanine; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Silver Staining; Tauopathies	2007
EEGs in phenylketonuria. I: Follow-up to adulthood; II: Short-term diet-related changes in EEGs and cognitive function. Developmental medicine and child neurology, 1993, Volume: 35, Issue:1 Topics: Adolescent; Adult; Brain; Child; Child, Preschool; Cognition Disorders; Electroencephalography; Female; Follow-Up Studies; Humans; Infant; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias	1993
Executive function and psychosocial adjustment in children with early treated phenylketonuria: correlation with historical and concurrent phenylalanine levels. Journal of intellectual disability research : JIDR, 1997, Volume: 41 ( Pt 4) Topics: Adjustment Disorders; Child; Child, Preschool; Cognition Disorders; Female; Humans; Infant; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias	1997
Prefrontal cortex cognitive deficits in children treated early and continuously for PKU. Monographs of the Society for Research in Child Development, 1997, Volume: 62, Issue:4 Topics: Age Factors; Analysis of Variance; Attention; Case-Control Studies; Child; Child, Preschool; Cognition Disorders; Cross-Sectional Studies; Female; Humans; Infant; Inhibition, Psychological; Intelligence; Longitudinal Studies; Male; Memory; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Regression Analysis; Sex Factors; Tyrosine; Volition	1997
The international study of pregnancy outcome in women with maternal phenylketonuria: report of a 12-year study. American journal of obstetrics and gynecology, 2000, Volume: 182, Issue:2 Topics: Adult; Child; Child, Preschool; Cognition Disorders; Diet, Protein-Restricted; Educational Status; Female; Heart Defects, Congenital; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Outcome; Prospective Studies; Social Class	2000
Sustained attention and inhibition of cognitive interference in treated phenylketonuria: associations with concurrent and lifetime phenylalanine concentrations. Neuropsychologia, 2002, Volume: 40, Issue:1 Topics: Adolescent; Age Factors; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Cognition Disorders; Female; Humans; Male; Phenylalanine; Phenylketonurias; Reaction Time; Regression Analysis; Task Performance and Analysis	2002
Neuropsychology of early-treated phenylketonuria: specific executive function deficits. Child development, 1990, Volume: 61, Issue:6 Topics: Child, Preschool; Cognition Disorders; Female; Follow-Up Studies; Humans; Intelligence; Male; Phenylalanine; Phenylketonurias	1990