phenylalanine and Cancer of Pancreas

phenylalanine has been researched along with Cancer of Pancreas in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.67)18.7374
1990's6 (20.00)18.2507
2000's13 (43.33)29.6817
2010's5 (16.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Aoki, M; Hatazawa, J; Horitsugi, G; Ikeda, H; Kanai, Y; Kongpracha, P; Nagamori, S; Naka, S; Shimosegawa, E; Watabe, T1
Inohara, H; Jin, C; Kanai, Y; Liu, X; Miyabe, J; Nagamori, S; Ohgaki, R; Ohki, H; Okuda, S; Quan, L; Saito, K; Wei, L; Yoshino, K1
Dejong, CHC; den Dulk, M; Grabsch, HI; Horstman, AMH; Olde Damink, SWM; Rensen, SS; Smeets, JSJ; van Dijk, DPJ; van Loon, LJC1
Castaño, JP; de Herder, WW; Dogan-Oruc, F; Feelders, RA; Herrera-Martínez, AD; Hofland, LJ; Van den Dungen, R; van Koetsveld, PM1
Padmanabhan, J; Woods, NK1
Gouverneur, E; Hellwig, D; Kirsch, CM; Menges, M; Raedle, J; Samnick, S; Schaefer, A1
Chan, L; Dahl, R; Fiji, HD; Kwon, O; Lu, J; Tamanoi, F1
Preston, T; Small, AC1
Herse, B; Mirzaie, M; Oster, O; Schöndube, F1
Buhr, HJ; Foitzik, T; Hines, OJ; Hotz, B; Hotz, HG; Reber, HA1
Bergers, G; Hanahan, D1
Barber, MD; Fearon, KC; McMillan, DC; Preston, T; Ross, JA; Slater, C2
Amon, M; Feiden, W; Hellwig, D; Kirsch, CM; Kubuschok, B; Menger, MD; Romeike, BF; Samnick, S1
Hellwig, D; Kirsch, CM; Menger, MD; Menges, M; Moellers, MO; Romeike, BF; Samnick, S; Schneider, G1
Armstrong, C; Durkin, AJ; Osborne, DA; Rosemurgy, AS; Yeatman, TJ; Zervos, EE1
Franz, MG; Gower, WR; Norman, JG; Rosemurgy, AS; Zervos, EE1
McCann, PP; Rasmussen, HS1
Rosemurgy, AS; Shafii, AE; Zervos, EE1
Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M1
Bergers, G; Folkman, J; Hanahan, D; Javaherian, K; Lo, KM1
Haq, M; Rosemurgy, AS; Shafii, AE; Zervos, EE1
Antoniu, BA; Compton, CC; Fernández-Del Castillo, C; Hartwig, W; Jimenez, RE; Warshaw, AL1
Haq, M; Rosemurgy, AS; Shafii, A; Zervos, EE1
Chiba, T; Itoh, Y; Kajita, M; Kinoh, H; Mori, H; Okada, A; Seiki, M1
Dingjan, PG; Postma, T; Stroes, JA1
Cha, CM; Cha, S; Mastrofrancesco, B; Randall, HT1
Barreto, M; Malaisse, WJ; Sener, A; Valverde, I1
Hine, P; Kay, G; Timperley, WR; Warnes, TW1
Karuzina, NP; Timofeevskaia, EA1

Reviews

1 review(s) available for phenylalanine and Cancer of Pancreas

ArticleYear
Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat.
    Pharmacology & therapeutics, 1997, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Enzyme Inhibitors; Female; Hemangioma; Humans; Hydroxamic Acids; Melanoma; Metalloendopeptidases; Mice; Ovarian Neoplasms; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Skin Neoplasms; Thiophenes

1997

Trials

2 trial(s) available for phenylalanine and Cancer of Pancreas

ArticleYear
Modulation of the liver export protein synthetic response to feeding by an n-3 fatty-acid-enriched nutritional supplement is associated with anabolism in cachectic cancer patients.
    Clinical science (London, England : 1979), 2004, Volume: 106, Issue:4

    Topics: Aged; Albumins; Cachexia; Chi-Square Distribution; Dietary Supplements; Fasting; Fatty Acids, Omega-3; Female; Fibrinogen; Humans; Liver; Male; Middle Aged; Nitrogen; Pancreatic Neoplasms; Phenylalanine; Statistics, Nonparametric

2004
Liver export protein synthetic rates are increased by oral meal feeding in weight-losing cancer patients.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:3

    Topics: Adult; Albumins; Eating; Female; Fibrinogen; Hormones; Humans; Kinetics; Liver; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Ultrafiltration; Weight Loss

2000

Other Studies

27 other study(ies) available for phenylalanine and Cancer of Pancreas

ArticleYear
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2.
    Annals of nuclear medicine, 2019, Volume: 33, Issue:6

    Topics: Animals; Blood Circulation; Boron Compounds; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Humans; Large Neutral Amino Acid-Transporter 1; Male; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Rats; Tissue Distribution; Tyrosine

2019
Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.
    Journal of pharmacological sciences, 2019, Volume: 139, Issue:3

    Topics: Animals; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Peptide Transporter 1; Phenylalanine; Symporters; Tyrosine; Up-Regulation; Xenograft Model Antitumor Assays

2019
Tumour-specific and organ-specific protein synthesis rates in patients with pancreatic cancer.
    Journal of cachexia, sarcopenia and muscle, 2019, Volume: 10, Issue:3

    Topics: Aged; Biopsy; Carbon Isotopes; Female; Humans; Liver; Male; Middle Aged; Muscle, Skeletal; Pancreas; Pancreatic Neoplasms; Pancreaticoduodenectomy; Phenylalanine; Protein Biosynthesis

2019
Effect of the Tryptophan Hydroxylase Inhibitor Telotristat on Growth and Serotonin Secretion in 2D and 3D Cultured Pancreatic Neuroendocrine Tumor Cells.
    Neuroendocrinology, 2020, Volume: 110, Issue:5

    Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; In Vitro Techniques; Neuroendocrine Tumors; Pancreatic Neoplasms; Phenylalanine; Pyrimidines; Serotonin; Tryptophan Hydroxylase; Tumor Cells, Cultured

2020
Inhibition of amyloid precursor protein processing enhances gemcitabine-mediated cytotoxicity in pancreatic cancer cells.
    The Journal of biological chemistry, 2013, Oct-18, Volume: 288, Issue:42

    Topics: ADAM Proteins; ADAM10 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Deoxycytidine; Dipeptides; Gemcitabine; Humans; Hydroxamic Acids; Membrane Proteins; Neoplasm Proteins; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Protein Structure, Tertiary; Thiophenes

2013
Para-[(123)I]iodo-L-phenylalanine in patients with pancreatic adenocarcinoma: tumour uptake, whole-body kinetics, dosimetry.
    Nuklearmedizin. Nuclear medicine, 2008, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Female; Half-Life; Humans; Iodine Radioisotopes; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Whole-Body Irradiation

2008
In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:5

    Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Enzyme Inhibitors; Female; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; Phenylalanine; Protein Prenylation; Sulfonamides; Xenograft Model Antitumor Assays

2009
Improved measurement of protein synthesis in human subjects using 2H-phenylalanine isotopomers and gas chromatography/mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2010, Mar-15, Volume: 24, Issue:5

    Topics: Albumins; Amino Acids; Deuterium; Esters; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Organosilicon Compounds; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins

2010
The matrix metalloproteinase inhibitor batimastat inhibits the lung colonisation of orthotopically implanted malignant pancreatic tumor cells in SCID mice.
    Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera, 2002, Volume: 8, Issue:4

    Topics: Animals; Antineoplastic Agents; Drug Evaluation; Injections, Intraperitoneal; Lung; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Mice; Mice, SCID; Neoplasm Transplantation; Pancreas; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes; Tumor Cells, Cultured

2002
Evaluation of vascular endothelial growth factor blockade and matrix metalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2003, Volume: 7, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Chi-Square Distribution; Disease Models, Animal; Drug Therapy, Combination; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreatic Neoplasms; Phenylalanine; Probability; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Combining antiangiogenic agents with metronomic chemotherapy enhances efficacy against late-stage pancreatic islet carcinomas in mice.
    Cold Spring Harbor symposia on quantitative biology, 2002, Volume: 67

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Islet Cell; Chronotherapy; Indoles; Matrix Metalloproteinase Inhibitors; Mice; Neovascularization, Pathologic; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Thiophenes

2002
p-[123I]iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.
    European journal of nuclear medicine and molecular imaging, 2004, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Drug Evaluation, Preclinical; Humans; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Pancreatic Neoplasms; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution

2004
Radioiodinated phenylalanine derivatives to image pancreatic cancer: a comparative study with [18F]fluoro-2-deoxy-D-glucose in human pancreatic carcinoma xenografts and in inflammation models.
    Nuclear medicine and biology, 2005, Volume: 32, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Disease Models, Animal; Fluorodeoxyglucose F18; Humans; Inflammation; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Transplantation, Heterologous

2005
EGF receptor antagonism improves survival in a murine model of pancreatic adenocarcinoma.
    The Journal of surgical research, 2006, Volume: 135, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Line, Tumor; Disease Models, Animal; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression; Humans; Mice; Mice, Nude; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Protein Kinase Inhibitors; Quinazolines; Survival Rate; Thiophenes

2006
Matrix metalloproteinase inhibition attenuates human pancreatic cancer growth in vitro and decreases mortality and tumorigenesis in vivo.
    The Journal of surgical research, 1997, Volume: 69, Issue:2

    Topics: Animals; Humans; Metalloendopeptidases; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes; Tumor Cells, Cultured

1997
Matrix metalloproteinase (MMP) inhibition selectively decreases type II MMP activity in a murine model of pancreatic cancer.
    The Journal of surgical research, 1999, Volume: 81, Issue:1

    Topics: Adenocarcinoma; Animals; Blotting, Western; Collagenases; Gelatinases; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes; Tumor Cells, Cultured

1999
Protein metabolism in glucagonoma.
    Diabetologia, 1999, Volume: 42, Issue:3

    Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine

1999
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice.
    Science (New York, N.Y.), 1999, Apr-30, Volume: 284, Issue:5415

    Topics: Angiostatins; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Islet Cell; Collagen; Cyclohexanes; Disease Progression; Drug Evaluation, Preclinical; Endostatins; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Staging; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Pancreatic Neoplasms; Peptide Fragments; Phenylalanine; Plasminogen; Sesquiterpenes; Thiophenes

1999
Matrix metalloproteinase inhibition suppresses MMP-2 activity and activation of PANC-1 cells in vitro.
    The Journal of surgical research, 1999, Jun-15, Volume: 84, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Gelatinases; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Neoplasm Invasiveness; Osmolar Concentration; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Thiophenes; Tumor Cells, Cultured

1999
Effect of matrix metalloproteinase inhibition on pancreatic cancer invasion and metastasis: an additive strategy for cancer control.
    Annals of surgery, 2000, Volume: 231, Issue:5

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Humans; Liver Neoplasms, Experimental; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; Phenylalanine; Thiophenes; Tumor Cells, Cultured

2000
Addition of matrix metalloproteinase inhibition to conventional cytotoxic therapy reduces tumor implantation and prolongs survival in a murine model of human pancreatic cancer.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Chromatography, Affinity; Deoxycytidine; Enzyme-Linked Immunosorbent Assay; Gemcitabine; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pancreatic Neoplasms; Phenylalanine; Thiophenes; Time Factors; Tumor Cells, Cultured

2000
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration.
    The Journal of cell biology, 2001, May-28, Volume: 153, Issue:5

    Topics: alpha-Amylases; Amino Acid Sequence; Animals; Cell Movement; Cell Size; Extracellular Matrix; Genes, Dominant; Humans; Hyaluronan Receptors; Leucine; Ligands; Matrix Metalloproteinase 14; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mice; Molecular Sequence Data; Neoplasm Invasiveness; Pancreatic Neoplasms; Phenylalanine; Plant Proteins; Protein Processing, Post-Translational; Sequence Deletion; Solubility; Sulfones; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Trypsin Inhibitors; Tumor Cells, Cultured

2001
The diagnostic value of certain alkaline phosphatase isoenzyme patterns in human serum, fractions obtained by polyacrylamide disc electrophoresis.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Apr-16, Volume: 60, Issue:2

    Topics: ABO Blood-Group System; Adenocarcinoma; Alkaline Phosphatase; Electrophoresis, Disc; Evaluation Studies as Topic; Humans; Isoenzymes; Liver Neoplasms; Methods; Neoplasm Metastasis; Neuraminidase; Pancreatic Neoplasms; Phenylalanine; Stomach Neoplasms

1975
Electrophoretic patterns of alkaline phosphatase isoenzymes in human sera with abnormally high activity, and an unusual band observed in sera of patients with pancreatic cancer.
    Clinical chemistry, 1975, Volume: 21, Issue:8

    Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Adult; Aged; Alkaline Phosphatase; Electrophoresis, Cellulose Acetate; Female; Gastrointestinal Neoplasms; Homoarginine; Hot Temperature; Humans; Intestines; Isoenzymes; Liver; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasms; Phenylalanine; Placenta

1975
Inhibition by a nonmetabolized analogue of L-leucine of protein biosynthesis in tumoral pancreatic islet cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:10

    Topics: Adenoma, Islet Cell; Amino Acids; Amino Acids, Cyclic; Keto Acids; Leucine; Neoplasm Proteins; Pancreatic Neoplasms; Phenylalanine; Serine; Tumor Cells, Cultured

1989
Pancreatic alkaline phosphatase and a tumour variant.
    Gut, 1972, Volume: 13, Issue:7

    Topics: Adenocarcinoma; Adenoma, Islet Cell; Alkaline Phosphatase; Bone and Bones; Carcinoma; Electrophoresis, Disc; Histocytochemistry; Hot Temperature; Humans; Intestine, Small; Isoenzymes; Liver; Pancreas; Pancreatic Neoplasms; Phenylalanine; Urea

1972
[The effect of thio-TEPA on the incorporation of labeled precursors into DNA and protein of human neoplastic cells in tissue culture].
    Doklady Akademii nauk SSSR, 1968, Volume: 178, Issue:2

    Topics: Carbon Isotopes; Culture Techniques; DNA, Neoplasm; Female; Humans; Neoplasm Proteins; Ovarian Neoplasms; Pancreatic Neoplasms; Phenylalanine; Stomach Neoplasms; Thiotepa; Thymidine

1968