Compounds > phenylalanine

phenylalanine and Breast Cancer

phenylalanine has been researched along with Breast Cancer in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19909 (17.65)18.7374
1990's6 (11.76)18.2507
2000's19 (37.25)29.6817
2010's15 (29.41)24.3611
2020's2 (3.92)2.80

Authors

AuthorsStudies
Asbjarnarson, A; Bergthorsson, JT; Gudjonsson, T; Ingthorsson, S; Joelsson, JP; Kricker, J; Lehmann, F; Nupponen, N; Schepsky, A; Slipicevic, A; Traustadottir, GA1
Andoh, T; Fujimoto, T; Ichikawa, H; Sakurai, Y; Satani, R; Sudo, T; Suzuki, M; Takata, T; Tanaka, H; Wada, K1
Afshan, T; Ghosh, JK; Kathuria, M; Kumari, T; Mitra, K; Sayeed, M; Shukla, PK; Tandon, A; Tripathi, AK1
Hayes, DF; Henry, NL; Hertz, DL; Kim, JH; Smith, EML; Stringer, KA; Sun, Y; Vangipuram, K; Yeomans, L1
Bellard, E; Belozertseva, E; Ben-Neji, M; Dalenc, F; Franchet, C; Gilhodes, J; Golzio, M; Gui, P; Labrousse, A; Le Cabec, V; Maridonneau-Parini, I; Poincloux, R1
Bao, Y; Ge, W; He, W; Hu, B; Li, Y; Lin, B; Liu, J; Liu, Y; Ma, E; Sheng, L; Wang, J; Yuan, L; Zou, C1
Bronich, TK; Desale, S; Kabanov, AV; Kim, JO; Oberoi, HS1
Antelmi, E; Busco, G; Cardone, RA; Casavola, V; Greco, MR; Guerra, L; Reshkin, SJ; Rubino, R1
Hathaway, HJ; Lu, J; Miao, Y; Prossnitz, ER; Royce, ME1
Kirkegaard, T; Kveiborg, M; Lykkesfeldt, AE; Yde, CW1
Astuti, P; Erden, W; Hertiani, T; Wahyuono, S1
Chen, GY; Kuo, CH; Liao, HW; Liao, WC; Lin, CH; Wu, MS1
Karchin, R; Mankoo, PK; Sukumar, S1
Dong, H; Guo, F; Li, Y; Li, Z; Liu, L; Shi, D; Wen, H; Xu, M1
Chin, B; Grasfeder, L; McDougald, D; Vaidyanathan, G; Zalutsky, MR1
Abbondanza, C; Auricchio, F; Barone, MV; Castoria, G; de Falco, A; De Rosa, C; Giovannelli, P; Giraldi, T; Lombardi, M; Migliaccio, A1
Li, J; Li, Y; Luo, Q; Ma, E; Miao, C; Mu, X; Sun, T; Xiao, W; Yuan, L1
Chen, QF; Li, D; Wang, HB; Wang, L; Wang, Y1
Auberger, P; Belhacène, N; Fromigué, O; Loubat, A; Louis, K; Mari, B; Shipp, M; Wu, E1
Li, P; Liu, H; Peach, ML; Roller, PP; Yang, D; Zhang, M1
LARIONOV, LF1
LORINCZ, AB; RYAN, WL1
Buesa, JM; de Buitrago, GG; Gómez-Moutón, C; Jiménez-Baranda, S; Lacalle, RA; Mañes, S; Martínez-A, C; Mira, E1
Ertongur, S; Gires, O; Lang, S; Mack, B; Muehlenweg, B; Wosikowski, K1
Devy, L; Foidart, JM; Frankenne, F; Grams, F; Krell, HW; Maquoi, E; Noël, A; Olivier, F; Sounni, NE1
Lin, D; Miao, X; Sun, T; Tan, W; Wang, J; Yu, C; Zhou, Y1
Liu, H; Meadows, GG; Núñez, NP1
Ashworth, A; dos Santos Silva, I; Fletcher, O; Johnson, N; McCormack, V; Palles, C; Peto, J; Whittaker, J1
Baxter, EJ; Campbell, PJ; Culligan, DA; Fourouclas, N; Green, AR; Huntly, BJ; Li, J; Munro, LR; Roberts, I; Scott, LM; Swanton, S; Vassiliou, GS1
Dyczynska, E; Sun, D; Syta, E; Zolkiewska, A1
Abreu, AS; Carvalho, MS; Ferreira, PM; Nazareth, N; Queiroz, MJ; São-José Nascimento, M1
Subramanian, VP; Walker, BK1
Bone, EA; Fife, R; Goulet, R; Qulali, M; Sledge, GW1
McCann, PP; Rasmussen, HS1
Baramova, E; Brown, P; Calberg-Bacq, CM; Foidart, JM; Hajitou, A; Kebers, F; L'Hoir, C; Lewalle, JM; Maquoi, E; Noël, A; Remacle, A1
Athota, AB; Chu, WS; Colclasure, JC; Kelly, T; Osborne, RL; Rozypal, TL; Yan, Y1
Albanell, J; Arribas, J; Baselga, J; Codony-Servat, J; Lopez-Talavera, JC1
Lacalle, RA; Mañes, S; Márquez, G; Martínez-A, C; Mira, E1
Albini, A; Buglioni, S; Ferrari, N; Ghiorzo, F; Morini, M; Mortarini, R; Mottolese, M; Natali, PG; Noonan, DM1
Bone, E; Lee, J; Mejia, S; Orr, W; Watson, P; Weber, M1
Albanell, J; Arribas, J; Baselga, J; Codony-Servat, J; Molina, MA; Rojo, F1
Ge, X; Meadows, GG; Zhang, H1
Brünner, N; Carmeliet, P; Dickson, RB; Frandsen, TL; Holst-Hansen, C; Johnson, MD; Low, JA; Stephens, RW1
Campbell, IT; Harvie, MN; Howell, A; Thatcher, N1
Andersen, TL; Brünner, N; Delaissé, JM; Foged, NT; Heegaard, AM; Holst-Hansen, C; Høegh-Andersen, P; Misander, H; NicAmhlaoibh, R; Winding, B1
Ortmeyer, AE; Shindelman, JE; Sussman, HH; Wada, HG1
Costanza, ME1
Galt, RM; Knock, FE; Oester, YT; Sylvester, R1
Griendl, W; Pittermann, E; Stacher, A1
Burdette, WJ1
Chong, L; Dunne, J; Fennelly, JJ; FitzGerald, M; McGeeney, K1

Reviews

3 review(s) available for phenylalanine and Breast Cancer

ArticleYear
Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk.
    Journal of the National Cancer Institute, 2006, Jul-19, Volume: 98, Issue:14

    Topics: Asian People; Aurora Kinase A; Aurora Kinases; Breast Neoplasms; Case-Control Studies; Female; Gene Frequency; Humans; Isoleucine; Linkage Disequilibrium; Odds Ratio; Phenylalanine; Polymorphism, Genetic; Protein Serine-Threonine Kinases; Publication Bias; Risk Assessment; Risk Factors; White People

2006
Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat.
    Pharmacology & therapeutics, 1997, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Enzyme Inhibitors; Female; Hemangioma; Humans; Hydroxamic Acids; Melanoma; Metalloendopeptidases; Mice; Ovarian Neoplasms; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Skin Neoplasms; Thiophenes

1997
Current progress in the management of cancer. A collective review.
    Plastic and reconstructive surgery, 1969, Volume: 44, Issue:3

    Topics: Adenocarcinoma; Angiography; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Chemotherapy, Cancer, Regional Perfusion; DNA, Neoplasm; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Lymphography; Lymphoma, Non-Hodgkin; Male; Mammography; Melanoma; Mustard Compounds; Neoplasms; Phenylalanine; Radioisotopes; Radionuclide Imaging; Radiotherapy Dosage; Selenium; Skin Neoplasms; Thermography; Time Factors

1969

Other Studies

48 other study(ies) available for phenylalanine and Breast Cancer

ArticleYear
Melflufen, a peptide-conjugated alkylator, is an efficient anti-neo-plastic drug in breast cancer cell lines.
    Cancer medicine, 2020, Volume: 9, Issue:18

    Topics: Animals; Antineoplastic Agents, Alkylating; Breast Neoplasms; CD13 Antigens; Cell Line, Tumor; Chick Embryo; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Leucyl Aminopeptidase; Melphalan; Phenylalanine; Signal Transduction; Tumor Suppressor p53-Binding Protein 1

2020
Preclinical study of boron neutron capture therapy for bone metastasis using human breast cancer cell lines.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 165

    Topics: Animals; Bone Neoplasms; Boron Compounds; Boron Neutron Capture Therapy; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Phenylalanine; Xenograft Model Antitumor Assays

2020
Selective phenylalanine to proline substitution for improved antimicrobial and anticancer activities of peptides designed on phenylalanine heptad repeat.
    Acta biomaterialia, 2017, 07-15, Volume: 57

    Topics: 3T3 Cells; Amino Acid Substitution; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Antineoplastic Agents; Breast Neoplasms; Escherichia coli; Female; Humans; Mice; Phenylalanine; Proline; RAW 264.7 Cells; Repetitive Sequences, Amino Acid; THP-1 Cells

2017
Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy.
    Breast cancer research and treatment, 2018, Volume: 171, Issue:3

    Topics: Adult; Aged; Biomarkers; Breast Neoplasms; Female; Histidine; Humans; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Paclitaxel; Peripheral Nervous System Diseases; Phenylalanine; Threonine

2018
The Protease-Dependent Mesenchymal Migration of Tumor-Associated Macrophages as a Target in Cancer Immunotherapy.
    Cancer immunology research, 2018, Volume: 6, Issue:11

    Topics: Amides; Animals; Breast Neoplasms; Cell Movement; Female; Humans; Immunotherapy; Macrophages; Matrix Metalloproteinases; Mesoderm; Mice, Inbred C57BL; Mice, Transgenic; Microscopy; Organ Culture Techniques; Otitis; Phenylalanine; Protease Inhibitors; Pyridines; rho-Associated Kinases; Thiophenes

2018
Discovery of a novel cathepsin inhibitor with dual autophagy-inducing and metastasis-inhibiting effects on breast cancer cells.
    Bioorganic chemistry, 2019, Volume: 84

    Topics: Autophagy; Binding Sites; Breast Neoplasms; Cathepsins; Cell Line, Tumor; Cell Movement; Drug Evaluation, Preclinical; Female; Humans; Inhibitory Concentration 50; Isoenzymes; Molecular Docking Simulation; Phenylalanine; Protease Inhibitors; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship

2019
Polypeptide nanogels with hydrophobic moieties in the cross-linked ionic cores: synthesis, characterization and implications for anticancer drug delivery.
    Journal of drug targeting, 2013, Volume: 21, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cross-Linking Reagents; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Gels; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Mice; Nanoparticles; Ovarian Neoplasms; Particle Size; Phenylalanine; Polyethylene Glycols; Polyglutamic Acid; Polymers; Time Factors; Xenograft Model Antitumor Assays

2013
Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: Anti-Arrhythmia Agents; Breast Neoplasms; Cathepsin B; Cation Transport Proteins; Cell Line, Tumor; Cell Surface Extensions; Extracellular Matrix; Female; Guanidines; Humans; Hydrogen-Ion Concentration; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Peptide Hydrolases; Phenylalanine; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones; Thiophenes

2014
Introduction of D-phenylalanine enhanced the receptor binding affinities of gonadotropin-releasing hormone peptides.
    Bioorganic & medicinal chemistry letters, 2014, Feb-01, Volume: 24, Issue:3

    Topics: Animals; Binding, Competitive; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Gonadotropin-Releasing Hormone; Heterografts; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Molecular Structure; Optical Imaging; Peptides; Phenylalanine; Protein Binding; Receptors, LHRH; Tomography, Emission-Computed, Single-Photon

2014
The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines.
    International journal of oncology, 2014, Volume: 45, Issue:1

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Fulvestrant; Humans; MCF-7 Cells; Phenylalanine; Phosphorylation; Protease Inhibitors; Receptor, ErbB-3; Thiophenes

2014
Pyrophen Produced by Endophytic Fungi Aspergillus sp Isolated from Piper crocatum Ruiz and Pav Exhibits Cytotoxic Activity and Induces S Phase Arrest in T47D Breast Cancer Cells.
    Asian Pacific journal of cancer prevention : APJCP, 2016, Volume: 17, Issue:2

    Topics: Animals; Apoptosis; Aspergillus; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Chlorocebus aethiops; Female; Humans; Phenylalanine; Piper; Plant Extracts; Proton Magnetic Resonance Spectroscopy; Pyrones; S Phase; Tumor Cells, Cultured; Vero Cells

2016
Development of a Postcolumn Infused-Internal Standard Liquid Chromatography Mass Spectrometry Method for Quantitative Metabolomics Studies.
    Journal of proteome research, 2017, 02-03, Volume: 16, Issue:2

    Topics: Breast Neoplasms; Calibration; Chromatography, Liquid; Female; Flow Injection Analysis; Humans; Metabolomics; Observer Variation; Phenylalanine; Principal Component Analysis; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tryptophan

2017
PIK3CA somatic mutations in breast cancer: Mechanistic insights from Langevin dynamics simulations.
    Proteins, 2009, May-01, Volume: 75, Issue:2

    Topics: Adenosine Triphosphate; Animals; Breast Neoplasms; Catalytic Domain; Class I Phosphatidylinositol 3-Kinases; Computer Simulation; Enzyme Stability; Humans; Models, Molecular; Mutation, Missense; Phenylalanine; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Conformation; Structural Homology, Protein; Temperature

2009
Highly efficient drug delivery nanosystem via L-phenylalanine triggering based on supramolecular polymer micelles.
    Macromolecular rapid communications, 2011, Mar-16, Volume: 32, Issue:6

    Topics: alpha-Cyclodextrins; Breast Neoplasms; Delayed-Action Preparations; Drug Delivery Systems; Female; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Micelles; Nanotechnology; Phenylalanine; Polymers

2011
An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:10

    Topics: Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Female; Humans; Iodine Radioisotopes; Isotope Labeling; Phenylalanine; Radiopharmaceuticals

2011
Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells.
    Oncogene, 2012, Nov-15, Volume: 31, Issue:46

    Topics: Active Transport, Cell Nucleus; Animals; Breast Neoplasms; Cell Cycle Checkpoints; Cell Growth Processes; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyclin D1; Cytoplasm; Estradiol; Estrogen Receptor alpha; Exportin 1 Protein; Female; Forkhead Transcription Factors; Humans; Karyopherins; MCF-7 Cells; Mice; Mutation; NIH 3T3 Cells; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; S Phase; src-Family Kinases; Transcription, Genetic; Tyrosine

2012
JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells.
    Toxicology and applied pharmacology, 2012, Aug-15, Volume: 263, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Proteins; Benzamides; Blotting, Western; Breast Neoplasms; Carcinoma; Cell Cycle; Cell Line, Tumor; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Phenylalanine; Reactive Oxygen Species; Up-Regulation

2012
Mesothelin promotes invasion and metastasis in breast cancer cells.
    The Journal of international medical research, 2012, Volume: 40, Issue:6

    Topics: Animals; Breast Neoplasms; Butadienes; Cell Line, Tumor; Cell Movement; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Lymphatic Metastasis; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; MCF-7 Cells; Mesothelin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Nitriles; Phenylalanine; Protease Inhibitors; Thiophenes; Transplantation, Heterologous

2012
Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase.
    International journal of cancer, 2003, Sep-01, Volume: 106, Issue:3

    Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Caspase Inhibitors; Cell Survival; Collagen; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Female; Humans; In Situ Nick-End Labeling; Laminin; Matrix Metalloproteinase 11; Metalloendopeptidases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphorylation; Protein Serine-Threonine Kinases; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiophenes; Transfection; Tumor Cells, Cultured; Tyrosine

2003
Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.
    Organic letters, 2003, Aug-21, Volume: 5, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acids; Animals; Breast Neoplasms; Fluorenes; GRB2 Adaptor Protein; Inhibitory Concentration 50; Mice; Molecular Mimicry; Molecular Sequence Data; Peptides, Cyclic; Phenylalanine; Phosphotyrosine; Proteins; Receptor, ErbB-2; src Homology Domains; Stereoisomerism; Tumor Cells, Cultured

2003
Experimental results with sarcolysine.
    Acta - Unio Internationalis Contra Cancrum, 1957, Volume: 13, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Melphalan; Phenylalanine

1957
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface.
    Journal of cell science, 2004, Apr-01, Volume: 117, Issue:Pt 9

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Dipeptides; Doxycycline; Enzyme Activation; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Microdomains; Membrane Proteins; Neovascularization, Pathologic; Phenylalanine; Protein Binding; Protein Transport; Receptors, LDL; Recombinant Fusion Proteins; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2004
Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system.
    International journal of cancer, 2004, Jul-20, Volume: 110, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Collagen; Drug Combinations; Female; Flow Cytometry; HeLa Cells; Humans; Laminin; Neoplasm Invasiveness; Neoplasm Metastasis; Phenylalanine; Proteoglycans; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Urokinase-Type Plasminogen Activator; Uterine Cervical Neoplasms

2004
Anti-invasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1

    Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Aorta; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Microscopy, Fluorescence; Models, Chemical; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Phenylalanine; Piperazines; Protease Inhibitors; Pyrimidines; Rats; Thiophenes; Time Factors; Up-Regulation

2004
Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma.
    Carcinogenesis, 2004, Volume: 25, Issue:11

    Topics: Adult; Aged; Amino Acid Substitution; Aurora Kinase A; Aurora Kinases; Breast Neoplasms; Confidence Intervals; Female; Gene Frequency; Genotype; Humans; Isoleucine; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Odds Ratio; Phenylalanine; Protein Serine-Threonine Kinases; Risk Factors

2004
PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells.
    Cancer letters, 2006, May-08, Volume: 236, Issue:1

    Topics: Amino Acids; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Immunologic Factors; Ligands; Male; Melanoma; Methionine; Phenylalanine; PPAR gamma; Prostaglandin D2; Prostatic Neoplasms; Thiazolidinediones; Tyrosine

2006
An acquired translocation in JAK2 Val617Phe-negative essential thrombocythemia associated with autosomal spread of X-inactivation.
    Haematologica, 2006, Volume: 91, Issue:8

    Topics: Amino Acid Substitution; Base Sequence; Blotting, Southern; Bone Marrow; Breast Neoplasms; Chromosome Disorders; Chromosome Mapping; Chromosome Walking; Chromosomes, Human, Pair 5; Chromosomes, Human, X; DNA Methylation; DNA Primers; Female; Humans; Janus Kinase 2; Middle Aged; Phenylalanine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sex Chromosome Disorders; Thrombocythemia, Essential; Translocation, Genetic; Valine

2006
Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein.
    International journal of cancer, 2008, Jun-01, Volume: 122, Issue:11

    Topics: ADAM Proteins; ADAM12 Protein; Animals; Aspartic Acid; Biotinylation; Blotting, Western; Breast Neoplasms; Cell Movement; Female; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Histidine; Humans; Immunoprecipitation; Leucine; Membrane Proteins; Mice; Mutation; Phenylalanine

2008
Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation.
    Bioorganic & medicinal chemistry, 2008, May-15, Volume: 16, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Central Nervous System Neoplasms; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Structure; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2008
Recent advances in breast cancer management.
    The West Virginia medical journal, 1980, Volume: 76, Issue:9

    Topics: Adjuvants, Pharmaceutic; Breast Neoplasms; Carcinoma; Estrogens; Female; Humans; Neoplasm Metastasis; Phenylalanine

1980
Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice.
    Journal of the National Cancer Institute, 1995, Oct-18, Volume: 87, Issue:20

    Topics: Animals; Breast Neoplasms; Chemotherapy, Adjuvant; Chi-Square Distribution; Collagenases; Female; Humans; Linear Models; Lung Neoplasms; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Recurrence, Local; Neoplasm Transplantation; Phenylalanine; RNA, Messenger; RNA, Neoplasm; Thiophenes; Tumor Cells, Cultured

1995
Inhibition of stromal matrix metalloproteases: effects on breast-tumor promotion by fibroblasts.
    International journal of cancer, 1998, Apr-13, Volume: 76, Issue:2

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Communication; Collagen; Drug Combinations; Fibroblasts; Gene Transfer Techniques; Humans; Laminin; Metalloendopeptidases; Mice; Mice, Nude; Phenylalanine; Protease Inhibitors; Proteoglycans; Stromal Cells; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured

1998
Proteolysis of extracellular matrix by invadopodia facilitates human breast cancer cell invasion and is mediated by matrix metalloproteinases.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:6

    Topics: Breast Neoplasms; Collagen; Enzyme Inhibitors; Extracellular Matrix; Female; Fibronectins; Humans; Metalloendopeptidases; Neoplasm Invasiveness; Neoplasm Proteins; Phenylalanine; Pseudopodia; Thiophenes; Tumor Cells, Cultured

1998
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells.
    Cancer research, 1999, Mar-15, Volume: 59, Issue:6

    Topics: Breast Neoplasms; Endopeptidases; Humans; Hydroxamic Acids; Metalloendopeptidases; Phenylalanine; Phosphorylation; Protease Inhibitors; Receptor, ErbB-2; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Tyrosine; Vanadates

1999
Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9.
    Endocrinology, 1999, Volume: 140, Issue:4

    Topics: Breast Neoplasms; Cell Membrane; Cell Movement; Collagenases; Culture Media, Conditioned; Humans; Insulin-Like Growth Factor I; Integrins; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phenylalanine; Polymerase Chain Reaction; Protease Inhibitors; Receptors, Vitronectin; RNA, Messenger; Thiophenes; Tumor Cells, Cultured

1999
The alpha 3 beta 1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (MMP-9) activity.
    International journal of cancer, 2000, Aug-01, Volume: 87, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Breast Neoplasms; Chemotaxis; Collagen; Enzyme Induction; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha3beta1; Integrins; Ligands; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Phenotype; Phenylalanine; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes; Tumor Cells, Cultured

2000
A matrix metalloproteinase inhibitor, batimastat, retards the development of osteolytic bone metastases by MDA-MB-231 human breast cancer cells in Balb C nu/nu mice.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Humans; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Phenylalanine; Thiophenes; Tumor Cells, Cultured

2001
Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells.
    Cancer research, 2001, Jun-15, Volume: 61, Issue:12

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Humans; Metalloendopeptidases; Peptide Fragments; Phenylalanine; Phenylmercuric Acetate; Phosphorylation; Protease Inhibitors; Protein Structure, Tertiary; Receptor, ErbB-2; Thiophenes; Trastuzumab; Tumor Cells, Cultured

2001
Specific amino acid deficiency alters the expression of genes in human melanoma and other tumor cell lines.
    The Journal of nutrition, 2001, Volume: 131, Issue:11 Suppl

    Topics: Blotting, Western; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Melanoma; Mitogen-Activated Protein Kinase Kinases; Phenylalanine; Phosphorylation; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Tyrosine

2001
Increased stromal expression of murine urokinase plasminogen activator in a human breast cancer xenograft model following treatment with the matrix metalloprotease inhibitor, batimastat.
    Breast cancer research and treatment, 2001, Volume: 68, Issue:3

    Topics: Animals; Blotting, Northern; Breast Neoplasms; DNA Primers; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Metalloendopeptidases; Mice; Mice, Nude; Phenylalanine; Plasminogen Activators; Polymerase Chain Reaction; Protease Inhibitors; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Stromal Cells; Thiophenes; Xenograft Model Antitumor Assays

2001
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2002, Volume: 15, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine

2002
Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Survival; Dipeptides; Female; Genetic Therapy; Humans; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Osteolysis; Phenylalanine; Protease Inhibitors; Thiophenes; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured

2002
Demonstration of placental alkaline phosphatase in human breast cancer.
    International journal of cancer, 1979, Jun-15, Volume: 23, Issue:6

    Topics: Alkaline Phosphatase; Breast Neoplasms; Electrophoresis, Polyacrylamide Gel; Female; Humans; Isoenzymes; Levamisole; Liver; Neoplasm Metastasis; Phenylalanine; Placenta; Radioimmunoassay

1979
Sounding Board. The problem of breast-cancer prophylaxis.
    The New England journal of medicine, 1975, Nov-20, Volume: 293, Issue:21

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphatic Metastasis; Mice; Neoplasm Metastasis; Phenylalanine; Time Factors

1975
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
    Oncology, 1974, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Cattle; Depression, Chemical; DNA, Neoplasm; Female; Fluorouracil; Humans; In Vitro Techniques; Iodoacetates; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; Mice; Neoplasms; Phenylalanine; Succinate Dehydrogenase; Thymidine; Tritium

1974
[Effect of a new cytostatic agent (peptichemio) on malignant neoplasms].
    Wiener medizinische Wochenschrift (1946), 1974, Apr-06, Volume: 124, Issue:14

    Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Colonic Neoplasms; Female; Hodgkin Disease; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Peptides; Phenylalanine; Polycythemia; Uterine Neoplasms

1974
The importance of varying molecular size, differential heat and urea inactivation of phosphatase in the identification of disease patterns.
    Annals of the New York Academy of Sciences, 1969, Oct-14, Volume: 166, Issue:2

    Topics: Adult; Alkaline Phosphatase; Biliary Tract Diseases; Breast Neoplasms; Carcinoma; Chemical Phenomena; Chemistry; Chromatography, Gel; Colonic Neoplasms; Electrophoresis, Disc; Female; Hot Temperature; Humans; Liver Diseases; Lung Neoplasms; Middle Aged; Molecular Weight; Phenylalanine; Protein Denaturation; Urea

1969