phenylalanine and Brain Neoplasms

phenylalanine has been researched along with Brain Neoplasms in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (5.71)	18.7374
1990's	24 (22.86)	18.2507
2000's	48 (45.71)	29.6817
2010's	21 (20.00)	24.3611
2020's	6 (5.71)	2.80

Authors

Authors	Studies
Chen, YW; Chou, FI; Lee, YJ; Lin, YC; Wang, SY	1
Aldossari, S; Lockyer, NP; McMahon, G; Moore, KL	1
Chaboub, N; Devillers, A; Girard, A; Le Jeune, F; Le Reste, PJ; Metais, A; Palard-Novello, X; Saint-Jalmes, H	1
Chen, YL; Chen, YW; Hu, YS; Huang, WS; Lee, JC; Li, CY; Lin, CS; Lin, KH; Lo, YW	1
Alamón, C; Cabral, P; Cerecetto, H; Couto, M; Dagrosa, MA; Nievas, S; Perona, M; Teixidor, F; Viñas, C	1
Fukuda, H; Hiratsuka, J	1
Fujimura, A; Furuya, S; Hanafusa, T; Ichikawa, Y; Igawa, K; Kamiya, A; Tsuchida, K; Ueda, A; Watanabe, K; Yasui, S; Yoshihashi, S	1
Adams, DJ; Bansal, V; Kulhari, H; Pooja, D; Shukla, R; Sistla, R; Telukutla, SR	1
Hattori, Y; Hermawan, A; Ishimura, M; Kirihata, M; Meiyanto, E; Ohta, Y; Qodria, L; Ramadani, RD; Susidarti, RA; Utomo, RY	1
Huang, C; McConathy, J; Rich, KM; Yuan, L	1
Borrmann, N; Friedrich, S; Hedrich, HJ; Knapp, WH; Krauss, JK; Meyer, GJ; Nakamura, M; Schwabe, K; Walte, A	1
Moss, RL; Sauerwein, WA; Wittig, A	1
Gabel, D; Sander, A; Wosniok, W	1
Kageji, T; Kumada, H; Mizobuchi, Y; Nagahiro, S; Nakagawa, Y	1
Barth, RF; Chandra, S; Haider, SA; Huo, T; Kabalka, GW; Shaikh, AL; Yang, W	1
Chang, CW; Chang, WY; Chen, JC; Li, JJ; Wang, HE; Yang, FY	1
Hao, E; Hiramatsu, R; Kawabata, S; Kuroiwa, T; Miyatake, S; Ono, K; Sakurai, Y; Suzuki, M; Tanaka, H; Vicente, MG	1
Barth, RF	2
Hermans, R; Jääskeläinen, J; Järviluoma, E; Kallio, M; Kulvik, M; Laakso, J; Paetau, A; Rasilainen, M; Ruokonen, I; Seppälä, M; Vähätalo, J	1
Fukutani, S; Hiraoka, M; Ono, K; Suzuki, M; Tanaka, H; Watanabe, T	1
Imahori, Y; Kajimoto, Y; Kawabata, S; Kirihata, M; Kuroiwa, T; Miyashita, M; Miyatake, S; Ono, K; Otsuki, Y; Shibata, MA; Yokoyama, K	1
H-Stenstam, B	1
Bozzali, M; Cametti, C; Capuani, S; Colasanti, M; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Pastore, FS; Porcari, P; Russo, S; Venturini, G	1
Cruickshank, GS; Detta, A	1
Bozzali, M; Cametti, C; Capuani, S; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Muolo, M; Pastore, FS; Porcari, P; Russo, S	1
Campanella, R; Capuani, S; D'Amore, E; Fasano, F; La Bella, A; Lecce, M; Maraviglia, B; Migneco, LM; Pastore, FS; Porcari, P	1
Inaji, M; Ishii, K; Ishiwata, K; Kimura, Y; Matsumura, A; Momose, T; Nariai, T; Ohno, K; Yamamoto, T	1
Kumada, H; Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Tsurubuchi, T; Yamamoto, T	1
Doi, A; Hiramatsu, R; Iida, K; Imahori, Y; Kawabata, S; Kirihata, M; Kumada, H; Kuroda, Y; Kuroiwa, T; Maruhashi, A; Masunaga, S; Michiue, H; Miyata, S; Miyatake, S; Nonoguchi, N; Ono, K; Sakurai, Y; Suzuki, M; Yokoyama, K	1
Boddy, A; Braithwaite, R; Chester, M; Chopra, A; Croswell, G; Cruickshank, GS; Detta, A; Doran, J; Elliot, M; Ford, S; Ghani, Z; Graham, N; Green, S; Halbert, G; Hardie, J; James, ND; Lockyer, N; Ngoga, D; Sheehan, TM; Steinfeldt, H; Sugar, R; Vickerman, J; Wojnecki, C	1
Barth, RF; Binns, P; Riley, K; Tjarks, W; Wu, G; Yang, W	1
Grote, M; Knapp, WH; Korkmaz, Z; Krull, D; Meyer, GJ; Sriyapureddy, SR; Walte, A	1
Farmakis, G; Grgic, A; Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Steudel, WI	1
Alexiou, GA; Fotopoulos, AD; Kyritsis, AP; Tsiouris, S; Voulgaris, S	1
Cheng, X; Guo, G; Jiang, X; Mao, X; Wang, P; Zhang, W; Zhang, X; Zhen, H	1
Chen, G; Chen, J; Du, Z; Huang, Q; Li, B; Sun, T; Wei, Y; Xie, X; Zhou, Y	1
Chen, YW; Chou, FI; Lin, YL; Wong, TT; Yang, FY; Yen, SH	1
Dießl, S; Flentje, M; Hänscheid, H; Israel, I; Löhr, M; Reiners, C; Samnick, S; Sweeney, R; Verburg, FA; Vince, GH	1
Chandra, S; Coderre, JA; Kabalka, GW; Lorey, DR; Smith, DR	1
Benninger, C; Blackburn, GL; Butchko, HH; Comer, CP; de Sonneville, LM; Geha, RS; Hertelendy, Z; Koestner, A; Leon, AS; Liepa, GU; Mayhew, DA; McMartin, KE; Mendenhall, CL; Munro, IC; Novotny, EJ; Renwick, AG; Schiffman, SS; Schomer, DL; Shaywitz, BA; Spiers, PA; Stargel, WW; Tephly, TR; Thomas, JA; Trefz, FK	1
Kabalka, GW; Khan, MK; Miller, LF; Nichols, TL; Smith, GT	1
Coderre, JA; Micca, PL; Morris, GM; Nawrocky, MM; Weissfloch, LE	1
Buchar, E; Färkkilä, M; Jääskeläinen, J; Järviluoma, E; Kallio, M; Kriz, O; Kulvik, M; Laakso, J; Rasilainen, M; Ruokonen, I; Vähätalo, J	1
Imahori, Y; Mineura, K; Takahashi, Y	1
Allen, GC; Brooke, SL; Day, JC; Heard, PJ; Oyedepo, AC; Patel, H	1
Chang, PF; Chen, FD; Chen, JC; Deng, WP; Hwang, JJ; Lee, JS; Liao, AH; Liu, RS; Wang, HE	1
Chang, SM; Chen, JC; Hsu, FY; Liu, RS; Wang, HE	1
Coderre, JA; Micca, PL; Morris, GM	1
Bandyopadhyaya, AK; Barth, RF; Binns, PJ; Ciesielski, MJ; Coderre, JA; Fenstermaker, RA; Patel, H; Riley, K; Thirumamagal, BT; Tjarks, W; Wu, G; Yang, W	1
Binns, PJ; Coderre, JA; Harling, OK; Hopewell, JW; Kiger, WS; Riley, KJ; Turcotte, JC	1
Capala, J; Dahlström, M; Lindström, A; Lindström, P; Wasteson, A	1
Al-Madhoun, AS; Barth, RF; Byun, Y; Chandra, S; Eriksson, S; Johnsamuel, J; Smith, DR; Tjarks, W; Yang, W	1
Bergenheim, AT; Capala, J; Henriksson, R; Roslin, M	1
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Sell, N	1
Imahori, Y; Mineura, K; Sasajima, H	1
Chang, CW; Chen, FD; Chen, JC; Chen, YF; Hsieh, CH; Hwang, JJ; Kai, JJ; Liu, RS; Wang, HE	1
Asano, T; Doi, A; Kajimoto, Y; Kawabata, S; Kirihata, M; Kuroiwa, T; Miyatake, S; Ono, K; Yokoyama, K; Yoshida, T	1
Eskola, O; Havu-Aurén, K; Jääskeläinen, J; Kiiski, J; Kulvik, M; Lehtiö, K; Minn, H; Oikonen, V; Vähätalo, J; Vuorinen, V	1
Brun, A; H-Stenstam, B; Pellettieri, L; Rezaei, A; Sköld, K	1
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S	1
Brandau, W; Farmakis, G; Israel, I; Samnick, S	1
Barth, RF; Chandra, S; Lorey, DR; Tjarks, W	1
Bergenheim, AT; Blomquist, E; Capala, J; Franzén, L; Henriksson, R; Lindahl, SA; Michanek, A; Salford, LG; Westlin, JE	1
Brandau, W; Farmakis, G; Hellwig, D; Kirsch, CM; Samnick, S; Schaefer, A; Wollenweber, F	1
Waggoner, WF	1
Flam, F	1
Fukuda, H; Ichihashi, M; Mishima, Y	1
Bailey, MQ; Barth, RF; Coderre, JA; Matalka, KZ; Moeschberger, ML; Rofstad, EK; Soloway, AH; Staubus, AE	2
Allen, BJ; Jones, R; Mallesch, JL; McCarthy, WH; Moore, DE; Stening, WA	1
Cai, J; Iwamoto, S; Kikuchi, H; Nemoto, H; Oda, Y; Ono, K; Takagaki, M; Yamamoto, Y	1
Barth, RF; Carpenter, DE; Goodman, JH; Moeschberger, ML; Yang, W	1
Hatazawa, J; Iida, H; Inugami, A; Kanno, I; Miura, S; Murakami, M; Ogawa, T; Sasajima, T; Uemura, K; Yasui, N	1
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Soloway, AH; Yang, W	1
Barth, RF; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W	1
Bergland, R; Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD; Liu, HB; Slatkin, DN	1
Hiratsuka, J; Honda, C; Ido, T; Imahori, Y; Mishima, Y; Ueda, S	1
Buonocore, E; Dyke, JP; Hübner, KF; Kabalka, GW; Longford, CP; Reddy, NK; Reid, WS; Roberts, TG; Smith, GT	1
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S	1
Bergland, RM; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD	1
Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Iwai, J; Joel, DD; Liu, HB; Wielopolski, L	1
Barth, RF; Bartus, RT; Goodman, JH; Moeschberger, ML; Yang, W	1
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM	1
Ye, SJ	1
Aziz, T; Capala, J; Chanana, A; Diaz, A; Peress, NS	1
Barth, RF; Boesel, CP; Goodman, JH; Joel, DD; Moeschberger, ML; Nawrocky, MM; Ono, K; Rotaru, JH; Soloway, AH; Yang, W	1
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Goodman, JH; Moeschberger, ML; Nawrocky, MM; Rotaru, JH; Yang, W	1
Feiden, W; Heimann, A; Kempski, O; Kirsch, CM; Richter, S; Romeike, BF; Samnick, S	1
Barth, RF; Boesel, CP; Bresnahan, JC; Goettl, VM; Hadjiconstantinou, M; Joel, DD; Nawrocky, MM; Rotaru, JH; Wilkie, DA; Yang, W	1
Busse, PM; Kiger, WS; Palmer, MR; Riley, KJ; Zamenhof, RG	1
Barth, RF; Chandra, S; Coderre, JA; Joel, DD; Smith, DR; Yang, W	1
Ehara, K; Hiratsuka, J; Iwakura, M; Kondoh, H; Mishima, Y; Tamaki, N	1
Barth, RF; Bartus, RT; Coderre, JA; Ferketich, AK; Moeschberger, ML; Nawrocky, MM; Rofstad, EK; Rotaru, JH; Yang, W	1
Bader, JB; Feiden, W; Hellwig, D; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S	1
Iida, H; Kanno, I; Miura, S; Murakami, M; Uemura, K	1
Adelman, LS; Cano, G; Harling, OK; Joyce, MA; Kerley, SE; Madoc-Jones, H; Saris, SC; Solares, GR; Wazer, DE; Zamenhof, RG	1
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM; Slatkin, DN	1
Barth, RF; Fairchild, RG; Soloway, AH	1
Coderre, JA; Fairchild, RG; Fand, I; Glass, JD; Joel, DD; Micca, PL	1
Kowada, M; Mineura, K; Shishido, F	1
Fujita, H; Higano, S; Inugami, A; Kanno, I; Miura, S; Murakami, M; Sasaki, H; Shishido, F; Takahashi, K; Tomura, N	1
Burke, JF; Mark, VH; Papadakis, N	1
Iversen, LL; Snodgrass, SR	1

Reviews

4 review(s) available for phenylalanine and Brain Neoplasms

Article	Year
Pharmacokinetics of Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 166 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography	2020
Boron neutron capture therapy at the crossroads: challenges and opportunities. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fast Neutrons; Glioma; Humans; Nuclear Reactors; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Randomized Controlled Trials as Topic; Rats; Sulfhydryl Compounds	2009
Aspartame: review of safety. Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:2 Pt 2 Topics: Affect; Animals; Aspartame; Behavior; Brain Neoplasms; Cognition; Drug Evaluation, Preclinical; Drug Hypersensitivity; Electroencephalography; Endocrine System; Headache; Humans; Methanol; Phenylalanine; Product Surveillance, Postmarketing; Seizures; Sweetening Agents; Weight Loss	2002
[Molecular imaging for brain tumor using positron emission tomography]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9 Topics: Amino Acids; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carbon Radioisotopes; Cell Proliferation; Diglycerides; Electrons; Fluorine Radioisotopes; Humans; Neoplasm Staging; Oligodeoxyribonucleotides, Antisense; Phenylalanine; Phospholipids; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; RNA, Messenger	2005

Trials

12 trial(s) available for phenylalanine and Brain Neoplasms

Article	Year
Optimization of time frame binning for FDOPA uptake quantification in glioma. PloS one, 2020, Volume: 15, Issue:4 Topics: Adult; Aged; Biological Transport; Brain; Brain Neoplasms; Female; Glioma; Humans; Kinetics; Male; Middle Aged; Monte Carlo Method; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Young Adult	2020
Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Germany; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Prevalence; Risk Factors; Survival Rate; Temozolomide; Treatment Outcome	2014
Correlation between radiation dose and histopathological findings in patients with gliblastoma treated with boron neutron capture therapy (BNCT). Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Glioblastoma; Humans; Neoplasm, Residual; Phenylalanine; Radiotherapy Dosage; Statistics as Topic; Sulfhydryl Compounds; Survival Rate; Treatment Outcome	2014
A cancer research UK pharmacokinetic study of BPA-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Aged; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Male; Mannitol; Phenylalanine; Radiation-Sensitizing Agents; United Kingdom	2009
Tolerance of normal human brain to boron neutron capture therapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Disorders of Excessive Somnolence; Glioblastoma; Humans; Melanoma; Phenylalanine; Radiation Tolerance	2004
Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT. European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:9 Topics: Adult; Aged; Brain Neoplasms; Female; Humans; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon	2005
Neuropathological postmortem evaluation of BNCT for GBM. Acta neurologica Scandinavica, 2007, Volume: 116, Issue:3 Topics: Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Follow-Up Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiotherapy Dosage; Treatment Outcome	2007
Intra-individual comparison of p-[123I]-iodo-L-phenylalanine and L-3-[123I]-iodo-alpha-methyl-tyrosine for SPECT imaging of gliomas. European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:1 Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Count; Female; Glioma; Humans; Male; Methyltyrosines; Middle Aged; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon	2008
Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2 Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Quality of Life; Survival Rate; Treatment Outcome	2008
Boron neutron capture therapy for glioblastoma multiforme using p-boronophenylalanine and epithermal neutrons: trial design and early clinical results. Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2 Topics: Adult; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neutrons; Nuclear Reactors; Phenylalanine; Tissue Distribution	1997
Boron neutron-capture therapy (BNCT) for glioblastoma multiforme (GBM) using the epithermal neutron beam at the Brookhaven National Laboratory. International journal of radiation oncology, biology, physics, 1998, Mar-01, Volume: 40, Issue:4 Topics: Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Feasibility Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Outcome	1998
A pharmacokinetic model for the concentration of 10B in blood after boronophenylalanine-fructose administration in humans. Radiation research, 2001, Volume: 155, Issue:4 Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Models, Biological; Phenylalanine; Skin Neoplasms	2001

Other Studies

89 other study(ies) available for phenylalanine and Brain Neoplasms

Article	Year
Evaluation of the Key Advantages between Two Modalities of Boronophenylalanine Administration for Clinical Boron Neutron Capture Therapy Using an Animal Model. Cells, 2022, 09-01, Volume: 11, Issue:17 Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Mouth Neoplasms; Phenylalanine	2022
Microdistribution and quantification of the boron neutron capture therapy drug BPA in primary cell cultures of human glioblastoma tumour by NanoSIMS. The Analyst, 2019, Nov-07, Volume: 144, Issue:21 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Intracellular Space; Mass Spectrometry; Molecular Imaging; Nanotechnology; Phenylalanine	2019
The importance of optimal ROIs delineation for FBPA-PET before BNCT. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 163 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Feasibility Studies; Humans; Phenylalanine; Positron-Emission Tomography	2020
Bimodal Therapeutic Agents Against Glioblastoma, One of the Most Lethal Forms of Cancer. Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Nov-11, Volume: 26, Issue:63 Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioblastoma; Humans; Mice; Pharmaceutical Preparations; Phenylalanine	2020
In Vitro Studies to Define the Cell-Surface and Intracellular Targets of Polyarginine-Conjugated Sodium Borocaptate as a Potential Delivery Agent for Boron Neutron Capture Therapy. Cells, 2020, 09-23, Volume: 9, Issue:10 Topics: Borohydrides; Boron Neutron Capture Therapy; Brain Neoplasms; Humans; Peptides; Phenylalanine; Sodium; Sulfhydryl Compounds	2020
Peptide grafted and self-assembled poly(γ-glutamic acid)-phenylalanine nanoparticles targeting camptothecin to glioma. Nanomedicine (London, England), 2017, Volume: 12, Issue:14 Topics: Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Nanoconjugates; Peptides, Cyclic; Phenylalanine; Polyglutamic Acid	2017
Cellular uptake evaluation of pentagamaboronon-0 (PGB-0) for boron neutron capture therapy (BNCT) against breast cancer cells. Investigational new drugs, 2019, Volume: 37, Issue:6 Topics: Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Curcumin; Female; Humans; Phenylalanine; Radiation-Sensitizing Agents	2019
Radiosynthesis and biological evaluation of alpha-[F-18]fluoromethyl phenylalanine for brain tumor imaging. Nuclear medicine and biology, 2013, Volume: 40, Issue:4 Topics: Animals; Biological Transport; Brain Neoplasms; Glioma; Male; Mice; Multimodal Imaging; Neoplasm Grading; Phenylalanine; Radiochemistry; Radionuclide Imaging	2013
Systemic treatment with 4-211Atphenylalanine enhances survival of rats with intracranial glioblastoma. Nuklearmedizin. Nuclear medicine, 2013, Dec-13, Volume: 52, Issue:6 Topics: Animals; Astatine; Brachytherapy; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Glioblastoma; Phenylalanine; Radiopharmaceuticals; Rats; Survival Rate; Treatment Outcome	2013
Glioblastoma, brain metastases and soft tissue sarcoma of extremities: candidate tumors for BNCT. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Animals; Borohydrides; Boron Compounds; Brain Neoplasms; Cell Line, Tumor; Extremities; Glioblastoma; Humans; Male; Mice; Mice, Nude; Phenylalanine; Radiotherapy Dosage; Sarcoma; Sulfhydryl Compounds; Tissue Distribution	2014
Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88 Topics: Animals; Boron Compounds; Brain Neoplasms; Drug Synergism; Female; Glioma; Levodopa; Melanoma; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Organ Specificity; Phenylalanine; Premedication; Tissue Distribution; Treatment Outcome	2014
Pharmacokinetic analysis and uptake of 18F-FBPA-Fr after ultrasound-induced blood-brain barrier disruption for potential enhancement of boron delivery for neutron capture therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:4 Topics: Animals; Apoptosis; Blood-Brain Barrier; Boron Compounds; Brain Neoplasms; Drug Delivery Systems; Glioma; Glycopeptides; In Situ Nick-End Labeling; Male; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Ultrasonics	2014
Tetrakis(p-carboranylthio-tetrafluorophenyl)chlorin (TPFC): application for photodynamic therapy and boron neutron capture therapy. Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:3 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioma; Male; Microscopy, Fluorescence; Phenylalanine; Photochemotherapy; Photosensitizing Agents; Porphyrins; Radiation-Sensitizing Agents; Rats, Inbred F344; Tissue Distribution	2015
From the laboratory to the clinic: How translational studies in animals have lead to clinical advances in boron neutron capture therapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2015, Volume: 106 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Melanoma; Phenylalanine; Translational Research, Biomedical	2015
Biodistribution of boron after intravenous 4-dihydroxyborylphenylalanine-fructose (BPA-F) infusion in meningioma and schwannoma patients: A feasibility study for boron neutron capture therapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2015, Volume: 106 Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Feasibility Studies; Female; Fructose; Humans; Infusions, Intravenous; Male; Meningioma; Middle Aged; Neurilemmoma; Phenylalanine; Tissue Distribution; Young Adult	2015
L-Phenylalanine preloading reduces the (10)B(n, α)(7)Li dose to the normal brain by inhibiting the uptake of boronophenylalanine in boron neutron capture therapy for brain tumours. Cancer letters, 2016, Jan-01, Volume: 370, Issue:1 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Drug; Humans; Phenylalanine; Radiation Dosage	2016
Evaluation of fluoride-labeled boronophenylalanine-PET imaging for the study of radiation effects in patients with glioblastomas. Journal of neuro-oncology, 2008, Volume: 89, Issue:2 Topics: Boranes; Brain Neoplasms; Evaluation Studies as Topic; Fluorodeoxyglucose F18; Follow-Up Studies; Glioblastoma; Humans; Magnetic Resonance Imaging; Phenylalanine; Positron-Emission Tomography; Retrospective Studies; Statistics, Nonparametric	2008
Comments to article: Henriksson R et al., Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA) Radiother Oncol (2008). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2 Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Trials, Phase II as Topic; Female; Fructose; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Quality of Life; Survival Rate; Treatment Outcome	2008
L-DOPA preloading increases the uptake of borophenylalanine in C6 glioma rat model: a new strategy to improve BNCT efficacy. International journal of radiation oncology, biology, physics, 2008, Oct-01, Volume: 72, Issue:2 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dopamine Agents; Glioma; Levodopa; Male; Phenylalanine; Rats	2008
L-amino acid transporter-1 and boronophenylalanine-based boron neutron capture therapy of human brain tumors. Cancer research, 2009, Mar-01, Volume: 69, Issue:5 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Proliferation; Humans; Immunohistochemistry; Large Neutral Amino Acid-Transporter 1; Phenylalanine; Proliferating Cell Nuclear Antigen	2009
Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioma; In Vitro Techniques; Levodopa; Magnetic Resonance Imaging; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar	2009
In vivo 19F MR imaging and spectroscopy for the BNCT optimization. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Fluorine; Glioma; In Vitro Techniques; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Tissue Distribution	2009
PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Algorithms; Astrocytoma; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carbon Radioisotopes; Glioblastoma; Glioma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted	2009
Dose distribution and clinical response of glioblastoma treated with boron neutron capture therapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Adult; Aged; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Photons; Radiotherapy Dosage; Retrospective Studies; Sulfhydryl Compounds; Survival Rate; Treatment Failure	2009
Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Protocols; Combined Modality Therapy; Glioblastoma; Humans; Japan; Phenylalanine; Prognosis; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Survival Rate	2009
Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioma; Head and Neck Neoplasms; Humans; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Rats; Rats, Inbred F344	2009
Synthesis and analysis of 2-[211At]-L-phenylalanine and 4-[211At]-L-phenylalanine and their uptake in human glioma cell cultures in-vitro. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2010, Volume: 68, Issue:6 Topics: Astatine; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Isotope Labeling; Phenylalanine; Radiopharmaceuticals	2010
Prospective study of p-[123I]iodo-L-phenylalanine and SPECT for the evaluation of newly diagnosed cerebral lesions: specific confirmation of glioma. European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:12 Topics: Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon	2010
99mTc-tetrofosmin SPECT for the evaluation of cerebral lesions. European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:12 Topics: Brain Neoplasms; Humans; Organophosphorus Compounds; Organotechnetium Compounds; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon	2010
Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax. BMC cancer, 2010, Dec-02, Volume: 10 Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Flow Cytometry; Gamma Rays; Glioblastoma; Humans; Microscopy, Electron, Transmission; Neutrons; Phenylalanine; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Time Factors	2010
Selective uptake of boronophenylalanine by glioma stem/progenitor cells. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2012, Volume: 70, Issue:8 Topics: Animals; Boranes; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Phenylalanine; Tissue Distribution	2012
Boron neutron capture therapy for glioblastoma multiforme: enhanced drug delivery and antitumor effect following blood-brain barrier disruption induced by focused ultrasound. Future oncology (London, England), 2012, Volume: 8, Issue:10 Topics: Animals; Blood-Brain Barrier; Boron Neutron Capture Therapy; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Humans; Phenylalanine; Rats; Sound; Tissue Distribution	2012
Patients with recurrent glioblastoma multiforme. Initial experience with p-[(131)I]iodo-L-phenylalanine and external beam radiation therapy. Nuklearmedizin. Nuclear medicine, 2013, Volume: 52, Issue:1 Topics: Adult; Aged; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Pilot Projects; Radionuclide Imaging; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Conformal; Treatment Outcome	2013
Imaging of fluorine and boron from fluorinated boronophenylalanine in the same cell at organelle resolution by correlative ion microscopy and confocal laser scanning microscopy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8 Topics: Boron; Boron Compounds; Brain Neoplasms; Fluorine; Glioblastoma; Humans; Image Processing, Computer-Assisted; Ions; Microscopy, Confocal; Mitochondria; Models, Chemical; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tomography, Emission-Computed; Tumor Cells, Cultured	2002
Improved treatment planning for boron neutron capture therapy for glioblastoma multiforme using fluorine-18 labeled boronophenylalanine and positron emission tomography. Medical physics, 2002, Volume: 29, Issue:10 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fluorine Radioisotopes; Glioblastoma; Humans; Magnetic Resonance Imaging; Necrosis; Neutrons; Phenylalanine; Radiometry; Radiotherapy Planning, Computer-Assisted; Time Factors; Tomography, Emission-Computed	2002
Long-term infusions of p-boronophenylalanine for boron neutron capture therapy: evaluation using rat brain tumor and spinal cord models. Radiation research, 2002, Volume: 158, Issue:6 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Male; Phenylalanine; Radiation-Sensitizing Agents; Radiometry; Rats; Rats, Inbred F344; Spinal Cord; Time Factors; X-Rays	2002
Clinical implementation of 4-dihydroxyborylphenylalanine synthesised by an asymmetric pathway. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2003, Volume: 18, Issue:2 Topics: Adult; Aged; Animals; Boron Compounds; Brain Neoplasms; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Middle Aged; Phenylalanine; Rats; Rats, Sprague-Dawley; Technology, Pharmaceutical	2003
Prognostic and therapeutic indicator of fluoroboronophenylalanine positron emission tomography in patients with gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Dec-01, Volume: 9, Issue:16 Pt 1 Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prognosis; Survival Rate; Tomography, Emission-Computed; Treatment Outcome	2003
Analysis of boron-10 in soft tissue by dynamic secondary ion mass spectrometry. Journal of microscopy, 2004, Volume: 213, Issue:1 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Disease Models, Animal; Glioblastoma; Gliosarcoma; Humans; Isotopes; Mice; Phenylalanine; Rats; Spectrometry, Mass, Secondary Ion; Tumor Cells, Cultured	2004
Evaluation of 4-borono-2-18F-fluoro-L-phenylalanine-fructose as a probe for boron neutron capture therapy in a glioma-bearing rat model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:2 Topics: Animals; Autoradiography; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fluorine Radioisotopes; Fructose; Glioma; Male; Phenylalanine; Rats; Rats, Inbred F344; Tissue Distribution; Tomography, Emission-Computed	2004
MicroPET-based pharmacokinetic analysis of the radiolabeled boron compound [18F]FBPA-F in rats with F98 glioma. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5 Topics: Animals; Boron Compounds; Brain Neoplasms; Fluorine Radioisotopes; Fructose; Glioma; Humans; Male; Phenylalanine; Positron-Emission Tomography; Rats; Rats, Inbred F344	2004
The effect of dexamethasone on the uptake of p-boronophenylalanine in the rat brain and intracranial 9L gliosarcoma. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5 Topics: Animals; Biological Transport, Active; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Edema; Brain Neoplasms; Dexamethasone; Gliosarcoma; Humans; Male; Phenylalanine; Rats; Rats, Inbred F344	2004
Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Glioma; Humans; Injections, Intravenous; Phenylalanine; Radiotherapy Dosage; Rats; Rats, Inbred F344; Recombinant Proteins; Tissue Distribution; Transfection	2004
Accumulation of boron in human malignant glioma cells in vitro is cell type dependent. Journal of neuro-oncology, 2004, Volume: 68, Issue:3 Topics: Boranes; Boron; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Cell Line, Tumor; Fibroblasts; Glioblastoma; Glioma; Humans; Phenylalanine	2004
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors. Cancer research, 2004, Sep-01, Volume: 64, Issue:17 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Division; Glioma; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Middle Aged; Phenylalanine; Phosphorylation; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion; Subcellular Fractions; Thymidine; Thymidine Kinase	2004
Distribution of BPA and metabolic assessment in glioblastoma patients during BNCT treatment: a microdialysis study. Journal of neuro-oncology, 2005, Volume: 71, Issue:3 Topics: Blood Glucose; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Microdialysis; Phenylalanine; Radiation-Sensitizing Agents	2005
Evaluation of pharmacokinetics of 4-borono-2-(18)F-fluoro-L-phenylalanine for boron neutron capture therapy in a glioma-bearing rat model with hyperosmolar blood-brain barrier disruption. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:11 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Glioma; Injections, Intra-Arterial; Male; Mannitol; Metabolic Clearance Rate; Organ Specificity; Osmolar Concentration; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution	2005
Pharmacokinetic study of BSH and BPA in simultaneous use for BNCT. Journal of neuro-oncology, 2006, Volume: 78, Issue:3 Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Drug Combinations; Drug Synergism; Glioma; Male; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Wistar; Statistics, Nonparametric; Sulfhydryl Compounds	2006
Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET. European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:1 Topics: Adult; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neurilemmoma; Neurofibromatoses; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals	2007
Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2008, Volume: 66, Issue:4 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Mice, Nude; Nuclear Medicine; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Specific Pathogen-Free Organisms; Tissue Distribution; Xenograft Model Antitumor Assays	2008
Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS). Journal of microscopy, 2008, Volume: 229, Issue:Pt 1 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Glioblastoma; Humans; Interphase; Mitosis; Phenylalanine; Spectrometry, Mass, Secondary Ion	2008
PET imaging with p-[I-124]iodo-l-phenylalanine as a new tool for diagnosis and postoperative control in patients with glioma. Clinical nuclear medicine, 2008, Volume: 33, Issue:6 Topics: Aged; Brain Neoplasms; Female; Glioma; Humans; Phenylalanine; Positron-Emission Tomography; Postoperative Care; Radiopharmaceuticals	2008
Aspartame--a review. Pediatric dentistry, 1984, Volume: 6, Issue:3 Topics: Animals; Aspartame; Brain Diseases; Brain Neoplasms; Child; Dental Caries; Dipeptides; Humans; Phenylalanine; Phenylketonurias; United States; United States Food and Drug Administration	1984
Cancer treatment. Will history repeat for boron capture therapy? Science (New York, N.Y.), 1994, Jul-22, Volume: 265, Issue:5171 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Trials as Topic; Glioblastoma; Humans; Japan; Phenylalanine; Radiation-Sensitizing Agents; United States	1994
[Neutron capture therapy for cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:3 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Humans; Infusions, Intravenous; Melanoma; Phenylalanine; Skin Neoplasms	1994
A nude rat model for neutron capture therapy of human intracerebral melanoma. International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Female; Humans; Male; Melanoma; Mice; Middle Aged; Neoplasm Transplantation; Phenylalanine; Rats; Rats, Nude; Tumor Cells, Cultured	1994
The pharmacokinetics of p-Boronophenylalanine.fructose in human patients with glioma and metastatic melanoma. International journal of radiation oncology, biology, physics, 1994, Mar-30, Volume: 28, Issue:5 Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioma; Humans; Melanoma; Phenylalanine; Radiation-Sensitizing Agents	1994
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent. Cancer research, 1993, Jul-15, Volume: 53, Issue:14 Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Cell Survival; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Rats; Rats, Nude; Tissue Distribution	1993
Hydroxylforms of p-boronophenylalanine as potential boron carriers on boron neutron capture therapy for malignant brain tumors. Cancer research, 1996, May-01, Volume: 56, Issue:9 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Survival; Glioma; Humans; Hydroxylation; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344	1996
Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption. Neurosurgery, 1996, Volume: 38, Issue:5 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Brain; Brain Neoplasms; Carotid Arteries; Dominance, Cerebral; Glioma; Injections, Intra-Arterial; Mannitol; Neoplasm Transplantation; Neutron Capture Therapy; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution; Tumor Cells, Cultured	1996
Quantitative evaluation of neutral amino acid transport in cerebral gliomas using positron emission tomography and fluorine-18 fluorophenylalanine. European journal of nuclear medicine, 1996, Volume: 23, Issue:8 Topics: Amino Acids; Biological Transport, Active; Brain; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Male; Middle Aged; Phenylalanine; Tomography, Emission-Computed	1996
Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption. Cancer research, 1997, Mar-15, Volume: 57, Issue:6 Topics: Alpha Particles; Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Carotid Arteries; Glioma; Injections, Intra-Arterial; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Sulfhydryl Compounds	1997
Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine. Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carotid Arteries; Fructose; Glioma; Humans; Infusions, Intra-Arterial; Injections, Intra-Arterial; Male; Mannitol; Phenylalanine; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution	1997
In vivo diagnosis of human malignant melanoma with positron emission tomography using specific melanoma-seeking 18F-DOPA analogue. Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2 Topics: Boron; Boron Compounds; Brain; Brain Neoplasms; Fluorine Radioisotopes; Humans; Isotopes; Lymphatic Metastasis; Melanoma; Phenylalanine; Tomography, Emission-Computed	1997
Evaluation of fluorine-18-BPA-fructose for boron neutron capture treatment planning. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:11 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Fructose; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed	1997
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:2 Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed	1998
Biodistribution of p-boronophenylalanine in patients with glioblastoma multiforme for use in boron neutron capture therapy. Neurosurgery, 1998, Volume: 42, Issue:3 Topics: Boron Compounds; Brain; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Injections, Intravenous; Neutron Capture Therapy; Osmolar Concentration; Phenylalanine; Radiation-Sensitizing Agents; Scalp; Tissue Distribution	1998
Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (Receptor-Mediated Permeabilizer-7). Neurosurgery, 1999, Volume: 44, Issue:2 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Carotid Arteries; Dose-Response Relationship, Drug; Glioma; Injections, Intra-Arterial; Injections, Intravenous; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution	1999
Effect of dose and infusion time on the delivery of p-boronophenylalanine for neutron capture therapy. Journal of neuro-oncology, 1999, Volume: 41, Issue:3 Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Gliosarcoma; Infusions, Intravenous; Metabolic Clearance Rate; Phenylalanine; Radiation-Sensitizing Agents; Rats; Tissue Distribution; Tumor Cells, Cultured	1999
Boron self-shielding effects on dose delivery of neutron capture therapy using epithermal beam and boronophenylalanine. Medical physics, 1999, Volume: 26, Issue:11 Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Humans; Models, Statistical; Monte Carlo Method; Phantoms, Imaging; Phenylalanine; Radiation Protection; Radiation-Sensitizing Agents; Radiotherapy Dosage	1999
Postmortem neuropathological features secondary to boron neutron capture therapy for glioblastoma multiforme. Journal of neuropathology and experimental neurology, 2000, Volume: 59, Issue:1 Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Female; Glioblastoma; Humans; Lewy Bodies; Male; Middle Aged; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Phenylalanine; Radiation-Sensitizing Agents	2000
Boron neutron capture therapy of brain tumors: enhanced survival and cure following blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine. International journal of radiation oncology, biology, physics, 2000, Apr-01, Volume: 47, Issue:1 Topics: Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Injections, Intra-Arterial; Phenylalanine; Radiation-Sensitizing Agents; Radiobiology; Radiotherapy Dosage; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Time Factors	2000
Improved survival after boron neutron capture therapy of brain tumors by Cereport-mediated blood-brain barrier modulation to enhance delivery of boronophenylalanine. Neurosurgery, 2000, Volume: 47, Issue:1 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Glioma; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution	2000
Investigation of iodine-123-labelled amino acid derivatives for imaging cerebral gliomas: uptake in human glioma cells and evaluation in stereotactically implanted C6 glioma rats. European journal of nuclear medicine, 2000, Volume: 27, Issue:10 Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Animals; beta-Alanine; Binding, Competitive; Blood-Brain Barrier; Brain Neoplasms; Cysteine; Glioblastoma; Humans; Iodine Radioisotopes; Isoquinolines; Male; Methyltyrosines; Neoplasm Transplantation; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serine; Tetrahydroisoquinolines; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured	2000
Boron neutron capture therapy of brain tumors: functional and neuropathologic effects of blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine. Journal of neuro-oncology, 2000, Volume: 48, Issue:3 Topics: Animals; Blood-Brain Barrier; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Carotid Artery, Internal; Cerebral Hemorrhage; Cognition; Eye; Eye Diseases; Injections, Intra-Arterial; Male; Motor Activity; Neurotoxins; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Tissue Distribution	2000
Quantitative imaging and microlocalization of boron-10 in brain tumors and infiltrating tumor cells by SIMS ion microscopy: relevance to neutron capture therapy. Cancer research, 2001, Nov-15, Volume: 61, Issue:22 Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Drug Administration Schedule; Gliosarcoma; Infusions, Intravenous; Isotopes; Male; Phenylalanine; Rats; Rats, Inbred F344; Spectrometry, Mass, Secondary Ion	2001
Effect of boron neutron capture therapy for melanotic and amelanotic melanoma transplanted into mouse brain. Pigment cell research, 2002, Volume: 15, Issue:1 Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Isotopes; Melanins; Melanoma, Amelanotic; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Phenylalanine; Radiation-Sensitizing Agents; Tumor Cells, Cultured	2002
Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine. International journal of radiation oncology, biology, physics, 2002, Mar-01, Volume: 52, Issue:3 Topics: Animals; Blood-Brain Barrier; Boron Compounds; Boron Neutron Capture Therapy; Bradykinin; Brain Neoplasms; Humans; Mannitol; Melanoma; Osmosis; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Nude	2002
Initial evaluation of the feasibility of single photon emission tomography with p-[123 I]iodo-L-phenylalanine for routine brain tumour imaging. Nuclear medicine communications, 2002, Volume: 23, Issue:2 Topics: Adult; Aged; Animals; Astrocytoma; Brain Neoplasms; Feasibility Studies; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Whole-Body Counting	2002
[Phenylalanine transport in the living human brain by a dynamic PET of L-[2-18F]-fluorophenylalanine]. Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:7 Topics: Biological Transport; Brain; Brain Neoplasms; Capillary Permeability; Humans; Models, Biological; p-Fluorophenylalanine; Phenylalanine; Tomography, Emission-Computed	1992
Boron neutron capture therapy for murine malignant gliomas. Cancer research, 1992, Sep-01, Volume: 52, Issue:17 Topics: Animals; Boron Compounds; Brain; Brain Neoplasms; Glioma; Mice; Mice, Inbred C57BL; Neutrons; Phenylalanine; Radiation-Sensitizing Agents; Survival Analysis	1992
Control of intracerebral gliosarcomas in rats by boron neutron capture therapy with p-boronophenylalanine. Radiation research, 1992, Volume: 129, Issue:3 Topics: Animals; Boron Compounds; Brain Neoplasms; Glioma; Male; Neoplasm Transplantation; Neutrons; Phenylalanine; Rats; Rats, Inbred F344	1992
Boron neutron capture therapy for cancer. Scientific American, 1990, Volume: 263, Issue:4 Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage	1990
Selective delivery of boron by the melanin precursor analogue p-boronophenylalanine to tumors other than melanoma. Cancer research, 1990, Jan-01, Volume: 50, Issue:1 Topics: Animals; Boron Compounds; Brain Neoplasms; Cell Line; Drug Carriers; Glioma; Humans; Isotopes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neutrons; Phenylalanine; Rats; Tissue Distribution; Transplantation, Heterologous	1990
Brain tumor imaging with synthesized 18F-fluorophenylalanine and positron emission tomography. Surgical neurology, 1989, Volume: 31, Issue:6 Topics: Astrocytoma; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioma; Humans; Middle Aged; p-Fluorophenylalanine; Phenylalanine; Tomography, Emission-Computed	1989
Aspartame. Review of safety issues. Council on Scientific Affairs. JAMA, 1985, Jul-19, Volume: 254, Issue:3 Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats	1985
[Clinical investigation of 18F-fluorophenylalanine for brain tumor imaging--comparison with 11C-methionine]. Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:12 Topics: Brain; Brain Neoplasms; Carbon Radioisotopes; Female; Fluorine Radioisotopes; Glioma; Humans; Methionine; Middle Aged; p-Fluorophenylalanine; Phenylalanine; Tomography, Emission-Computed	1988
Effect of treatment with L-phenylalanine mustard and antibody on survival time of mice with intracerebral ependymoblastomas. Surgical forum, 1972, Volume: 23, Issue:0 Topics: Animals; Antibodies; Brain Neoplasms; Ependymoma; Immunotherapy; Mice; Mice, Inbred C3H; Mustard Compounds; Phenylalanine	1972
Amino acid uptake into human brain tumors. Brain research, 1974, Aug-09, Volume: 76, Issue:1 Topics: Absorption; Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Astrocytoma; Autoradiography; Brain Neoplasms; Chloromercuribenzoates; Culture Techniques; Cyanides; Ependymoma; Glutamates; Glycine; Humans; Lysine; Ouabain; Phenylalanine; Taurine; Time Factors; Tritium; Tryptophan; Valine	1974