phenylalanine and Brain Diseases

phenylalanine has been researched along with Brain Diseases in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199017 (56.67)18.7374
1990's6 (20.00)18.2507
2000's4 (13.33)29.6817
2010's3 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chien, HC; Colas, C; Giacomini, KM; Hall, C; Schlessinger, A; Thomas, AA; Wells, A; Wolfe, H1
Hurkat, P; Jain, A; Jain, SK; Vyas, A1
Hoeksma, M; Reijngoud, DJ; van Spronsen, FJ1
Gynther, M; Isotalo, A; Laine, K; Leppänen, J; Malmioja, K; Peura, L; Rautio, J1
Hartfield, DS; Yager, JY1
Buist, R; Owens, T; Peeling, J; Schellenberg, A; Sun, XJ; Toft-Hansen, H1
Dennis, DM; Glushakov, AV; Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Yarotskyy, V1
Carver, MJ; Copenhaver, JH; Schain, RJ; Underdahl, NR1
Waggoner, WF1
Rybakowa, M; Stepniewski, M1
Bick, U; Fünders, B; Hahn-Ullrich, H; Koch, HG; Ludolph, A; Möller, H; Schuierer, G; Ullrich, K; Weglage, J1
Bick, U; Ludolph, AC; Möller, H; Oberwittler, C; Schuierer, G; Stöber, U; Ullrich, K; Weglage, J; Wendel, U1
Hájek, M; Hejcmanová, L; Prádný, J1
Bouletreau, P; Delafosse, B; Motin, J1
Blass, JP; Milne, JF1
Hommes, FA1
Brenton, D; Davidson, DC; Kendall, B; Lees, AJ; Rylance, G; Smith, I; Thompson, AJ; Youl, BD1
Burri, R; Herschkowitz, N; Lazeyras, F; Matthieu, JM; Posse, S; Vandevelde, M1
Buttè, C; Giovannini, M; Longhi, R; Paccanelli, S; Riva, E; Valsasina, R1
Xiao, L1
Brenton, DP1
Fischer, JE; Hasselgren, PO1
Pardridge, WM1
Elliott, RB; Lewis, SA; Lyon, IC1
Drásilová, L; Kaniová, V; Mrskos, A; Podhradská, O; Snopková, J1
Menkes, JH1
Grüttner, R; Rybak, C; Sternowsky, HJ1
LaRamée, MA; Lowden, JA1
Cooksey, B; O'Reilly, S1

Reviews

8 review(s) available for phenylalanine and Brain Diseases

ArticleYear
Brain dysfunction in phenylketonuria: is phenylalanine toxicity the only possible cause?
    Journal of inherited metabolic disease, 2009, Volume: 32, Issue:1

    Topics: Amino Acids, Neutral; Animals; Blood-Brain Barrier; Brain; Brain Diseases; Cytotoxins; Humans; Models, Biological; Phenylalanine; Phenylketonurias

2009
Neurologic manifestations of iron deficiency in childhood.
    Pediatric neurology, 2002, Volume: 27, Issue:2

    Topics: Anemia, Iron-Deficiency; Brain Diseases; Child; Child, Preschool; Developmental Disabilities; Dopamine; gamma-Aminobutyric Acid; Humans; Infant; Iron Deficiencies; Phenylalanine; Pseudotumor Cerebri; Serotonin; Stroke

2002
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
    Recent patents on CNS drug discovery, 2006, Volume: 1, Issue:3

    Topics: Animals; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydroxyl Radical; Mental Disorders; Neuroprotective Agents; Phenylalanine; Synaptic Transmission; Tyrosine

2006
White matter abnormalities in phenylketonuria: results of magnetic resonance measurements.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1994, Volume: 407

    Topics: Brain Chemistry; Brain Diseases; Case-Control Studies; Demyelinating Diseases; Electrophysiology; Humans; Magnetic Resonance Imaging; Phenylalanine; Phenylketonurias

1994
White matter abnormalities in patients with treated hyperphenylalaninaemia: magnetic resonance relaxometry and proton spectroscopy findings.
    European journal of pediatrics, 1993, Volume: 152, Issue:12

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phenylalanine; Phenylketonurias

1993
[Variation of plasma amino acids in severe hepatitis with encephalopathy 10 cases].
    La Nouvelle presse medicale, 1977, Apr-09, Volume: 6, Issue:14

    Topics: Acute Disease; Adult; Aged; Amino Acids; Binding, Competitive; Blood-Brain Barrier; Brain; Brain Diseases; Female; Hepatitis; Humans; Hydroxylation; Isoleucine; Leucine; Male; Middle Aged; Neurotransmitter Agents; Phenylalanine; Tyrosine; Valine

1977
On the mechanism of permanent brain dysfunction in hyperphenylalaninemia.
    Biochemical medicine and metabolic biology, 1991, Volume: 46, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias

1991
Septic encephalopathy. Etiology and management.
    Intensive care medicine, 1986, Volume: 12, Issue:1

    Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Brain; Brain Diseases; Guinea Pigs; Humans; Infections; Neurotransmitter Agents; Phenylalanine; Rats; Toxins, Biological; Tryptophan; Tyrosine

1986

Other Studies

22 other study(ies) available for phenylalanine and Brain Diseases

ArticleYear
l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Antineoplastic Agents; Brain Diseases; Click Chemistry; Dose-Response Relationship, Drug; Histidine; Humans; Large Neutral Amino Acid-Transporter 1; Molecular Structure; Neoplasms; Prodrugs; Structure-Activity Relationship; Triazoles; Tryptophan

2019
Targeting of AIDS related encephalopathy using phenylalanine anchored lipidic nanocarrier.
    Colloids and surfaces. B, Biointerfaces, 2015, Jul-01, Volume: 131

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Animals; Benzoxazines; Blood-Brain Barrier; Brain Diseases; Cells, Cultured; Cyclopropanes; Drug Carriers; Female; Humans; Lipids; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Phenylalanine; Rats, Wistar; Reverse Transcriptase Inhibitors; Tissue Distribution

2015
Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery.
    Molecular pharmaceutics, 2011, Oct-03, Volume: 8, Issue:5

    Topics: Algorithms; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Diseases; Central Nervous System Agents; Drug Design; Drug Stability; Gas Chromatography-Mass Spectrometry; Infusions, Intra-Arterial; Isomerism; Large Neutral Amino Acid-Transporter 1; Male; Molecular Structure; Phenylalanine; Prodrugs; Rats; Spectrometry, Mass, Electrospray Ionization; Valproic Acid

2011
Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Nov-15, Volume: 177, Issue:10

    Topics: Animals; Brain; Brain Diseases; Cell Movement; Central Nervous System; Chemokine CCL2; Cytokines; Female; Gene Expression Regulation; Inflammation Mediators; Injections, Intraperitoneal; Male; Metalloproteases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pertussis Toxin; Phenylalanine; Thiophenes; Weight Loss

2006
Protein metabolism in the developing brain: influence of birth and gestational age.
    Science (New York, N.Y.), 1967, May-19, Volume: 156, Issue:3777

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Diseases; Carbon Isotopes; Nerve Tissue Proteins; Phenylalanine; Swine

1967
Aspartame--a review.
    Pediatric dentistry, 1984, Volume: 6, Issue:3

    Topics: Animals; Aspartame; Brain Diseases; Brain Neoplasms; Child; Dental Caries; Dipeptides; Humans; Phenylalanine; Phenylketonurias; United States; United States Food and Drug Administration

1984
[Effect of growth hormone on the transport of leucine and phenylalanine through the erythrocyte membrane in children with hypothalamo-hypophyseal insufficiency].
    Endokrynologia Polska, 1982, Volume: 33, Issue:1-3

    Topics: Biological Transport; Brain Diseases; Cells, Cultured; Child; Child, Preschool; Erythrocyte Membrane; Erythrocytes; Female; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Leucine; Male; Phenylalanine; Pituitary Diseases

1982
Proton in vivo spectroscopy of patients with hyperphenylalaninaemia.
    Neuropediatrics, 1993, Volume: 24, Issue:2

    Topics: Adult; Aspartic Acid; Biopterins; Brain; Brain Chemistry; Brain Diseases; Child; Choline; Creatine; Demyelinating Diseases; Female; Humans; Magnetic Resonance Imaging; Male; Phenylalanine; Phenylketonurias

1993
Newer concepts of psychiatric diagnosis and biochemical research on mental illness.
    Lancet (London, England), 1977, Apr-02, Volume: 1, Issue:8014

    Topics: Brain Diseases; Humans; Mental Disorders; Metabolism, Inborn Errors; Phenethylamines; Phenylalanine

1977
Neurological deterioration in young adults with phenylketonuria.
    Lancet (London, England), 1990, Sep-08, Volume: 336, Issue:8715

    Topics: Adult; Brain; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Male; Patient Compliance; Phenylalanine; Phenylketonurias; Retrospective Studies; Time Factors

1990
Brain damage and recovery in hyperphenylalaninemic rats.
    Developmental neuroscience, 1990, Volume: 12, Issue:2

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Body Weight; Brain Diseases; Magnetic Resonance Spectroscopy; Myelin Sheath; Organ Size; Phenylalanine; Phenylketonurias; Rats; Rats, Inbred Strains; Sulfotransferases; Sulfurtransferases

1990
Cranial computerized tomography in dihydropteridine reductase deficiency.
    Journal of inherited metabolic disease, 1985, Volume: 8, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Atrophy; Basal Ganglia Diseases; Brain Diseases; Calcinosis; Developmental Disabilities; Female; Humans; Infant; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Tomography, X-Ray Computed

1985
[Plasma amino acid changes in 40 cases of chronic cor pulmonale].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1989, Volume: 12, Issue:5

    Topics: Aged; Aged, 80 and over; Amino Acids; Amino Acids, Branched-Chain; Brain Diseases; Female; Humans; Leucine; Male; Middle Aged; Phenylalanine; Pulmonary Heart Disease

1989
Maternal phenylketonuria.
    European journal of clinical nutrition, 1989, Volume: 43 Suppl 1

    Topics: Brain Diseases; Cohort Studies; Embryonic and Fetal Development; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome

1989
Aspartame. Review of safety issues. Council on Scientific Affairs.
    JAMA, 1985, Jul-19, Volume: 254, Issue:3

    Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats

1985
The safety of aspartame.
    JAMA, 1986, Nov-21, Volume: 256, Issue:19

    Topics: Adult; Aspartame; Brain Diseases; Child; Dipeptides; Humans; Phenylalanine

1986
Outcome of pregnancy in the rat with mild hyperphenylalaninaemia and hypertyrosinaemia: implications for the management of "human maternal PKU".
    Journal of inherited metabolic disease, 1985, Volume: 8, Issue:3

    Topics: Animals; Brain Diseases; Discrimination, Psychological; Disease Models, Animal; Female; Motor Activity; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Space Perception; Tyrosine

1985
Impaired glucose homeostasis in phenylketonurics.
    Acta Universitatis Carolinae. Medica. Monographia, 1973, Volume: 56

    Topics: Adolescent; Blood Glucose; Brain Diseases; Child; Child, Preschool; Glucose; Glucose Tolerance Test; Homeostasis; Humans; Hypoglycemia; Infant; Intellectual Disability; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Starvation; Time Factors

1973
Biochemical approaches to the nosology of nervous system defects, III.
    Birth defects original article series, 1971, Volume: 7, Issue:1

    Topics: Ammonia; Biopsy; Brain; Brain Chemistry; Brain Diseases; Cells, Cultured; Chromatography; Fabry Disease; Humans; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lipidoses; Lipids; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Spectrometry, Fluorescence

1971
[Clinical problems of the genetic heterogeneity in hyperphenylalaninemias].
    Monatsschrift fur Kinderheilkunde, 1971, Volume: 119, Issue:11

    Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Diet Therapy; Dietary Proteins; Electroencephalography; Female; Humans; Phenylalanine; Phenylketonurias; Protein Deficiency; Tyrosine

1971
Hyperphenylalaninemia: the effect of cerebral amino acid levels during development.
    Canadian journal of biochemistry, 1969, Volume: 47, Issue:9

    Topics: Age Factors; Amino Acids; Animals; Brain; Brain Chemistry; Brain Diseases; Injections, Subcutaneous; Myelin Sheath; Phenylalanine; Rats; Time Factors; Tyrosine

1969
The relationship between 5-hydroxyindoles and catecholamines.
    Neurology, 1965, Volume: 15, Issue:12

    Topics: Blood-Brain Barrier; Brain Chemistry; Brain Diseases; Catecholamines; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Movement Disorders; Phenylalanine; Serotonin; Tryptophan; Urine

1965