phenylalanine and Astrocytoma, Grade IV

phenylalanine has been researched along with Astrocytoma, Grade IV in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (21.28)18.2507
2000's20 (42.55)29.6817
2010's14 (29.79)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Bennet, KE; Castellanos, M; Chang, SY; Chantigian, S; Guerrero, J; Manciu, FS; Manciu, M; Martinez Lopez, LV; Rahman, M1
Aldossari, S; Lockyer, NP; McMahon, G; Moore, KL1
Alamón, C; Cabral, P; Cerecetto, H; Couto, M; Dagrosa, MA; Nievas, S; Perona, M; Teixidor, F; Viñas, C1
Fukuda, H; Hiratsuka, J1
Adams, DJ; Bansal, V; Kulhari, H; Pooja, D; Shukla, R; Sistla, R; Telukutla, SR1
Anbai, A; Harada, T; Hashimoto, M; Hirose, K; Sato, M; Takai, Y; Wada, Y; Watanabe, T1
Arai, Y; Fujii, H; Honda, N; Itami, J; Kawai, K; Kurihara, H; Ohe, K; Yoshimoto, M1
Borrmann, N; Friedrich, S; Hedrich, HJ; Knapp, WH; Krauss, JK; Meyer, GJ; Nakamura, M; Schwabe, K; Walte, A1
Moss, RL; Sauerwein, WA; Wittig, A1
Kinashi, Y; Kitajima, E; Kubota, Y; Okayasu, R; Okumura, K; Ono, K; Takahashi, S1
Gabel, D; Sander, A; Wosniok, W1
Kageji, T; Kumada, H; Mizobuchi, Y; Nagahiro, S; Nakagawa, Y1
Ahmad, T; Barth, RF; Chandra, S; Kabalka, GW1
Imahori, Y; Kajimoto, Y; Kawabata, S; Kirihata, M; Kuroiwa, T; Miyashita, M; Miyatake, S; Ono, K; Otsuki, Y; Shibata, MA; Yokoyama, K1
H-Stenstam, B1
Inaji, M; Ishii, K; Ishiwata, K; Kimura, Y; Matsumura, A; Momose, T; Nariai, T; Ohno, K; Yamamoto, T1
Kumada, H; Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Tsurubuchi, T; Yamamoto, T1
Doi, A; Hiramatsu, R; Iida, K; Imahori, Y; Kawabata, S; Kirihata, M; Kumada, H; Kuroda, Y; Kuroiwa, T; Maruhashi, A; Masunaga, S; Michiue, H; Miyata, S; Miyatake, S; Nonoguchi, N; Ono, K; Sakurai, Y; Suzuki, M; Yokoyama, K1
Cheng, X; Guo, G; Jiang, X; Mao, X; Wang, P; Zhang, W; Zhang, X; Zhen, H1
Blass, G; Israel, I; Reiners, C; Samnick, S1
Chen, YW; Chou, FI; Lin, YL; Wong, TT; Yang, FY; Yen, SH1
Dießl, S; Flentje, M; Hänscheid, H; Israel, I; Löhr, M; Reiners, C; Samnick, S; Sweeney, R; Verburg, FA; Vince, GH1
Chandra, S; Coderre, JA; Kabalka, GW; Lorey, DR; Smith, DR1
Kabalka, GW; Khan, MK; Miller, LF; Nichols, TL; Smith, GT1
Allen, GC; Brooke, SL; Day, JC; Heard, PJ; Oyedepo, AC; Patel, H1
Binns, PJ; Coderre, JA; Harling, OK; Hopewell, JW; Kiger, WS; Riley, KJ; Turcotte, JC1
Capala, J; Dahlström, M; Lindström, A; Lindström, P; Wasteson, A1
Bergenheim, AT; Capala, J; Henriksson, R; Roslin, M1
Brun, A; H-Stenstam, B; Pellettieri, L; Rezaei, A; Sköld, K1
Brandau, W; Farmakis, G; Israel, I; Samnick, S1
Barth, RF; Chandra, S; Lorey, DR; Tjarks, W1
Bergenheim, AT; Blomquist, E; Capala, J; Franzén, L; Henriksson, R; Lindahl, SA; Michanek, A; Salford, LG; Westlin, JE1
Flam, F1
Bergland, R; Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD; Liu, HB; Slatkin, DN1
Buonocore, E; Dyke, JP; Hübner, KF; Kabalka, GW; Longford, CP; Reddy, NK; Reid, WS; Roberts, TG; Smith, GT1
Bailey, SF; Fuhr, JE; Kabalka, GW1
Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Gebbers, JO; Joel, DD; Micca, PL; Nawrocky, MM; Peress, NS; Shady, M; Slatkin, DN1
Fujii, R; Ido, T; Imahori, Y; Kusuki, T; Ohmori, Y; Ono, K; Ueda, S1
Bergland, RM; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Joel, DD1
Capala, J; Chadha, M; Chanana, AD; Coderre, JA; Elowitz, EH; Iwai, J; Joel, DD; Liu, HB; Wielopolski, L1
Coderre, JA; Joel, DD; Micca, PL; Nawrocky, MM1
Aziz, T; Capala, J; Chanana, A; Diaz, A; Peress, NS1
Feiden, W; Heimann, A; Kempski, O; Kirsch, CM; Richter, S; Romeike, BF; Samnick, S1
Busse, PM; Kiger, WS; Palmer, MR; Riley, KJ; Zamenhof, RG1
Bader, JB; Feiden, W; Hellwig, D; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S1
Chandra, S; Lorey II, DR; Smith, DR1
Barth, RF; Fairchild, RG; Soloway, AH1

Reviews

1 review(s) available for phenylalanine and Astrocytoma, Grade IV

ArticleYear
Pharmacokinetics of
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 166

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Humans; Isotopes; Melanoma; Neoplasms; Phenylalanine; Positron-Emission Tomography

2020

Trials

8 trial(s) available for phenylalanine and Astrocytoma, Grade IV

ArticleYear
Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Germany; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Prevalence; Risk Factors; Survival Rate; Temozolomide; Treatment Outcome

2014
Correlation between radiation dose and histopathological findings in patients with gliblastoma treated with boron neutron capture therapy (BNCT).
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Glioblastoma; Humans; Neoplasm, Residual; Phenylalanine; Radiotherapy Dosage; Statistics as Topic; Sulfhydryl Compounds; Survival Rate; Treatment Outcome

2014
Tolerance of normal human brain to boron neutron capture therapy.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2004, Volume: 61, Issue:5

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Disorders of Excessive Somnolence; Glioblastoma; Humans; Melanoma; Phenylalanine; Radiation Tolerance

2004
Neuropathological postmortem evaluation of BNCT for GBM.
    Acta neurologica Scandinavica, 2007, Volume: 116, Issue:3

    Topics: Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Follow-Up Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiotherapy Dosage; Treatment Outcome

2007
Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2

    Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Quality of Life; Survival Rate; Treatment Outcome

2008
Boron neutron capture therapy for glioblastoma multiforme using p-boronophenylalanine and epithermal neutrons: trial design and early clinical results.
    Journal of neuro-oncology, 1997, Volume: 33, Issue:1-2

    Topics: Adult; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neutrons; Nuclear Reactors; Phenylalanine; Tissue Distribution

1997
Boron neutron-capture therapy (BNCT) for glioblastoma multiforme (GBM) using the epithermal neutron beam at the Brookhaven National Laboratory.
    International journal of radiation oncology, biology, physics, 1998, Mar-01, Volume: 40, Issue:4

    Topics: Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Dose-Response Relationship, Radiation; Feasibility Studies; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Outcome

1998
A pharmacokinetic model for the concentration of 10B in blood after boronophenylalanine-fructose administration in humans.
    Radiation research, 2001, Volume: 155, Issue:4

    Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fructose; Glioblastoma; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Models, Biological; Phenylalanine; Skin Neoplasms

2001

Other Studies

38 other study(ies) available for phenylalanine and Astrocytoma, Grade IV

ArticleYear
Assessing Nordihydroguaiaretic Acid Therapeutic Effect for Glioblastoma Multiforme.
    Sensors (Basel, Switzerland), 2022, Mar-30, Volume: 22, Issue:7

    Topics: Antioxidants; Glioblastoma; Humans; Masoprocol; Phenylalanine; Reactive Oxygen Species

2022
Microdistribution and quantification of the boron neutron capture therapy drug BPA in primary cell cultures of human glioblastoma tumour by NanoSIMS.
    The Analyst, 2019, Nov-07, Volume: 144, Issue:21

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Intracellular Space; Mass Spectrometry; Molecular Imaging; Nanotechnology; Phenylalanine

2019
Bimodal Therapeutic Agents Against Glioblastoma, One of the Most Lethal Forms of Cancer.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Nov-11, Volume: 26, Issue:63

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioblastoma; Humans; Mice; Pharmaceutical Preparations; Phenylalanine

2020
Peptide grafted and self-assembled poly(γ-glutamic acid)-phenylalanine nanoparticles targeting camptothecin to glioma.
    Nanomedicine (London, England), 2017, Volume: 12, Issue:14

    Topics: Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Nanoconjugates; Peptides, Cyclic; Phenylalanine; Polyglutamic Acid

2017
Impact of oxygen status on 10B-BPA uptake into human glioblastoma cells, referring to significance in boron neutron capture therapy.
    Journal of radiation research, 2018, Mar-01, Volume: 59, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Boron Compounds; Boron Neutron Capture Therapy; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Large Neutral Amino Acid-Transporter 1; Oxygen; Phenylalanine; RNA, Messenger

2018
Predominant contribution of L-type amino acid transporter to 4-borono-2-(18)F-fluoro-phenylalanine uptake in human glioblastoma cells.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:5

    Topics: Amino Acid Transport Systems; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography

2013
Systemic treatment with 4-211Atphenylalanine enhances survival of rats with intracranial glioblastoma.
    Nuklearmedizin. Nuclear medicine, 2013, Dec-13, Volume: 52, Issue:6

    Topics: Animals; Astatine; Brachytherapy; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Glioblastoma; Phenylalanine; Radiopharmaceuticals; Rats; Survival Rate; Treatment Outcome

2013
Glioblastoma, brain metastases and soft tissue sarcoma of extremities: candidate tumors for BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Animals; Borohydrides; Boron Compounds; Brain Neoplasms; Cell Line, Tumor; Extremities; Glioblastoma; Humans; Male; Mice; Mice, Nude; Phenylalanine; Radiotherapy Dosage; Sarcoma; Sulfhydryl Compounds; Tissue Distribution

2014
Dose-rate effect was observed in T98G glioma cells following BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Radiation; Glioblastoma; Humans; Phenylalanine; Radiotherapy Dosage; Treatment Outcome

2014
Quantitative evaluation of boron neutron capture therapy (BNCT) drugs for boron delivery and retention at subcellular-scale resolution in human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
    Journal of microscopy, 2014, Volume: 254, Issue:3

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Calcium; Cell Line, Tumor; Cell Tracking; Glioblastoma; Humans; Intracellular Space; Isotopes; Microscopy, Confocal; Phenylalanine; Potassium; Sodium; Spectrometry, Mass, Secondary Ion; Time Factors

2014
Evaluation of fluoride-labeled boronophenylalanine-PET imaging for the study of radiation effects in patients with glioblastomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Boranes; Brain Neoplasms; Evaluation Studies as Topic; Fluorodeoxyglucose F18; Follow-Up Studies; Glioblastoma; Humans; Magnetic Resonance Imaging; Phenylalanine; Positron-Emission Tomography; Retrospective Studies; Statistics, Nonparametric

2008
Comments to article: Henriksson R et al., Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA) Radiother Oncol (2008).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2

    Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Trials, Phase II as Topic; Female; Fructose; Glioblastoma; Humans; Male; Middle Aged; Phenylalanine; Quality of Life; Survival Rate; Treatment Outcome

2008
PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Algorithms; Astrocytoma; Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Carbon Radioisotopes; Glioblastoma; Glioma; Humans; Methionine; Phenylalanine; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted

2009
Dose distribution and clinical response of glioblastoma treated with boron neutron capture therapy.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Adult; Aged; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Photons; Radiotherapy Dosage; Retrospective Studies; Sulfhydryl Compounds; Survival Rate; Treatment Failure

2009
Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:7-8 Suppl

    Topics: Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Protocols; Combined Modality Therapy; Glioblastoma; Humans; Japan; Phenylalanine; Prognosis; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Survival Rate

2009
Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax.
    BMC cancer, 2010, Dec-02, Volume: 10

    Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Flow Cytometry; Gamma Rays; Glioblastoma; Humans; Microscopy, Electron, Transmission; Neutrons; Phenylalanine; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Time Factors

2010
Validation of an amino-acid-based radionuclide therapy plus external beam radiotherapy in heterotopic glioblastoma models.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Phenylalanine; Radiotherapy; Rats; Transplantation, Heterotopic

2011
Boron neutron capture therapy for glioblastoma multiforme: enhanced drug delivery and antitumor effect following blood-brain barrier disruption induced by focused ultrasound.
    Future oncology (London, England), 2012, Volume: 8, Issue:10

    Topics: Animals; Blood-Brain Barrier; Boron Neutron Capture Therapy; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Humans; Phenylalanine; Rats; Sound; Tissue Distribution

2012
Patients with recurrent glioblastoma multiforme. Initial experience with p-[(131)I]iodo-L-phenylalanine and external beam radiation therapy.
    Nuklearmedizin. Nuclear medicine, 2013, Volume: 52, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Pilot Projects; Radionuclide Imaging; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Conformal; Treatment Outcome

2013
Imaging of fluorine and boron from fluorinated boronophenylalanine in the same cell at organelle resolution by correlative ion microscopy and confocal laser scanning microscopy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8

    Topics: Boron; Boron Compounds; Brain Neoplasms; Fluorine; Glioblastoma; Humans; Image Processing, Computer-Assisted; Ions; Microscopy, Confocal; Mitochondria; Models, Chemical; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tomography, Emission-Computed; Tumor Cells, Cultured

2002
Improved treatment planning for boron neutron capture therapy for glioblastoma multiforme using fluorine-18 labeled boronophenylalanine and positron emission tomography.
    Medical physics, 2002, Volume: 29, Issue:10

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Fluorine Radioisotopes; Glioblastoma; Humans; Magnetic Resonance Imaging; Necrosis; Neutrons; Phenylalanine; Radiometry; Radiotherapy Planning, Computer-Assisted; Time Factors; Tomography, Emission-Computed

2002
Analysis of boron-10 in soft tissue by dynamic secondary ion mass spectrometry.
    Journal of microscopy, 2004, Volume: 213, Issue:1

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Disease Models, Animal; Glioblastoma; Gliosarcoma; Humans; Isotopes; Mice; Phenylalanine; Rats; Spectrometry, Mass, Secondary Ion; Tumor Cells, Cultured

2004
Accumulation of boron in human malignant glioma cells in vitro is cell type dependent.
    Journal of neuro-oncology, 2004, Volume: 68, Issue:3

    Topics: Boranes; Boron; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Cell Line, Tumor; Fibroblasts; Glioblastoma; Glioma; Humans; Phenylalanine

2004
Distribution of BPA and metabolic assessment in glioblastoma patients during BNCT treatment: a microdialysis study.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Blood Glucose; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Glioblastoma; Humans; Microdialysis; Phenylalanine; Radiation-Sensitizing Agents

2005
Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2008, Volume: 66, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Mice, Nude; Nuclear Medicine; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Specific Pathogen-Free Organisms; Tissue Distribution; Xenograft Model Antitumor Assays

2008
Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
    Journal of microscopy, 2008, Volume: 229, Issue:Pt 1

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line; Glioblastoma; Humans; Interphase; Mitosis; Phenylalanine; Spectrometry, Mass, Secondary Ion

2008
Cancer treatment. Will history repeat for boron capture therapy?
    Science (New York, N.Y.), 1994, Jul-22, Volume: 265, Issue:5171

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Clinical Trials as Topic; Glioblastoma; Humans; Japan; Phenylalanine; Radiation-Sensitizing Agents; United States

1994
Evaluation of fluorine-18-BPA-fructose for boron neutron capture treatment planning.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:11

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Female; Fluorine Radioisotopes; Fructose; Glioblastoma; Humans; Middle Aged; Phenylalanine; Radiation-Sensitizing Agents; Tomography, Emission-Computed

1997
In vitro effects of boron-containing compounds upon glioblastoma cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 216, Issue:3

    Topics: Boron Compounds; Boron Neutron Capture Therapy; Bromodeoxyuridine; Cell Cycle; Cell Division; DNA Replication; Flow Cytometry; Fluorine Radioisotopes; Fructose; Glioblastoma; Humans; Phenylalanine; Tumor Cells, Cultured

1997
Biodistribution of boronophenylalanine in patients with glioblastoma multiforme: boron concentration correlates with tumor cellularity.
    Radiation research, 1998, Volume: 149, Issue:2

    Topics: Boron; Boron Compounds; Boron Neutron Capture Therapy; Glioblastoma; Humans; Phenylalanine; Tissue Distribution

1998
Fluorine-18-labeled fluoroboronophenylalanine PET in patients with glioma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:2

    Topics: Astrocytoma; Boron Compounds; Brain Neoplasms; Cerebrovascular Circulation; Fluorine Radioisotopes; Glioblastoma; Glioma; Humans; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed

1998
Biodistribution of p-boronophenylalanine in patients with glioblastoma multiforme for use in boron neutron capture therapy.
    Neurosurgery, 1998, Volume: 42, Issue:3

    Topics: Boron Compounds; Brain; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Injections, Intravenous; Neutron Capture Therapy; Osmolar Concentration; Phenylalanine; Radiation-Sensitizing Agents; Scalp; Tissue Distribution

1998
Effect of dose and infusion time on the delivery of p-boronophenylalanine for neutron capture therapy.
    Journal of neuro-oncology, 1999, Volume: 41, Issue:3

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Glioblastoma; Gliosarcoma; Infusions, Intravenous; Metabolic Clearance Rate; Phenylalanine; Radiation-Sensitizing Agents; Rats; Tissue Distribution; Tumor Cells, Cultured

1999
Postmortem neuropathological features secondary to boron neutron capture therapy for glioblastoma multiforme.
    Journal of neuropathology and experimental neurology, 2000, Volume: 59, Issue:1

    Topics: Adult; Aged; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Female; Glioblastoma; Humans; Lewy Bodies; Male; Middle Aged; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Phenylalanine; Radiation-Sensitizing Agents

2000
Investigation of iodine-123-labelled amino acid derivatives for imaging cerebral gliomas: uptake in human glioma cells and evaluation in stereotactically implanted C6 glioma rats.
    European journal of nuclear medicine, 2000, Volume: 27, Issue:10

    Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Animals; beta-Alanine; Binding, Competitive; Blood-Brain Barrier; Brain Neoplasms; Cysteine; Glioblastoma; Humans; Iodine Radioisotopes; Isoquinolines; Male; Methyltyrosines; Neoplasm Transplantation; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serine; Tetrahydroisoquinolines; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured

2000
Initial evaluation of the feasibility of single photon emission tomography with p-[123 I]iodo-L-phenylalanine for routine brain tumour imaging.
    Nuclear medicine communications, 2002, Volume: 23, Issue:2

    Topics: Adult; Aged; Animals; Astrocytoma; Brain Neoplasms; Feasibility Studies; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Whole-Body Counting

2002
Quantitative subcellular secondary ion mass spectrometry (SIMS) imaging of boron-10 and boron-11 isotopes in the same cell delivered by two combined BNCT drugs: in vitro studies on human glioblastoma T98G cells.
    Radiation research, 2002, Volume: 157, Issue:6

    Topics: Borohydrides; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Division; Cell Size; Glioblastoma; Humans; Organelles; Phenylalanine; Radioisotopes; Spectrometry, Mass, Secondary Ion; Sulfhydryl Compounds; Time Factors; Tumor Cells, Cultured

2002
Boron neutron capture therapy for cancer.
    Scientific American, 1990, Volume: 263, Issue:4

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Boron; Boron Compounds; Brain Neoplasms; Glioblastoma; Humans; Immunotoxins; Isotopes; Melanoma; Mice; Neoplasms; Neutrons; Phenylalanine; Radiation Dosage

1990