phenylalanine and Aging

phenylalanine has been researched along with Aging in 175 studies

Research

Studies (175)

TimeframeStudies, this research(%)All Research%
pre-199097 (55.43)18.7374
1990's24 (13.71)18.2507
2000's31 (17.71)29.6817
2010's17 (9.71)24.3611
2020's6 (3.43)2.80

Authors

AuthorsStudies
Buck, LB; Petrascheck, M; Ye, X1
Ford, S; Hofman, DL; MacDonald, A; Vardy, ERLC1
Burd, NA; Churchward-Venne, TA; de Groot, LCPGM; Dirks, ML; Fuchs, CJ; Gorissen, SHM; Groen, BBL; Holwerda, AM; Horstman, AMH; Koopman, R; Kouw, IWK; Pennings, B; Res, PT; Senden, JMG; Steijns, JMJM; Trommelen, J; van Loon, LJC; Verdijk, LB; Wall, BT1
Bai, P; Chen, F; Chen, J; Li, M; Mao, D; Wang, R; Yang, L; Yang, X; Zhang, Y; Zhao, W1
Church, DD; Ferrando, AA; Gwin, JA; Hirsch, KR; Kim, IY; Park, S; Pasiakos, SM; Wolfe, RR1
Ball, RO; Chang, J; Courtney-Martin, G; Elango, R; Kong, D; Lebarron, M; Pencharz, PB; Rafii, M; Szwiega, S; Xu, L1
Abatan, A; Adnot, S; Breau, M; Bréhat, J; Czibik, G; d'Humières, T; Delmont, T; Derumeaux, G; Halfaoui, M; Hatem, S; Liang, H; Marion, O; Martel, C; Mezdari, Z; Morin, D; Murat Altintas, D; Naushad, S; Pini, M; Radu, C; Sarwar, R; Sawaki, D; Suffee, N; Yavari, A; Zhang, Y1
Barta, AG; Reismann, P; Sumánszki, C1
Bůžková, P; Carbone, LD; Coughlin, SS; Fink, HA; Isales, CM; Le, B; Raiford, M; Robbins, JA; Shikany, JM1
Ball, RO; Courtney-Martin, G; Elango, R; Martin, KE; Pencharz, PB; Rafii, M; Szwiega, S1
Boirie, Y; Moreau, K; Walrand, S1
Ball, RO; Campbell, WW; Elango, R; McCabe, GP; Pencharz, PB; Tang, M1
Burd, NA; Gijsen, AP; Gorissen, SH; Groen, BB; Hamer, HM; van Loon, LJ1
Berillo, L; Caputi, C; Carducci, C; Chiarotti, F; Di Biasi, C; Leuzzi, V; Manti, F; Mastrangelo, M; Nardecchia, F1
Agergaard, J; Bülow, J; Holm, L; Kjaer, M; Reitelseder, S1
Biolo, G; Di Girolamo, FG; Gasparini, M; Grassi, B; Lazzer, S; Mazzucco, S; Narici, M; Passaro, A; Pišot, R; Reggiani, C; Rittweger, J; Šimunič, B; Situlin, R1
Eriksson, JG; Guzzardi, MA; Iozzo, P; Kajantie, E; Kautiainen, H; Salonen, MK1
Aarsland, A; Chinkes, DL; Katsanos, CS; Paddon-Jones, D; Wolfe, RR; Zhang, XJ1
Paddon-Jones, D; Sheffield-Moore, M; Symons, TB; Wolfe, RR1
Chan, L; Guan, X; Guo, Y; Li, X; Wang, Y1
Almeida, MF; Azevedo, I; Borges, N; Cardoso, ML; Carmona, C; Lima, MR; Rocha, JC; Salcedo, G; Soares, I; van Spronsen, FJ1
Dickinson, JM; Drummond, MJ; Fry, CS; Glynn, EL; Gundermann, DM; Rasmussen, BB; Timmerman, KL; Volpi, E; Walker, DK1
Mamerow, MM; Paddon-Jones, D; Sheffield-Moore, M; Symons, TB; Wolfe, RR1
Ahmad, M; Casperson, SL; Dillon, EL; Durham, WJ; Kinsky, MP; Randolph, KM; Sheffield-Moore, M; Urban, RJ; Volpi, E1
Bian, YH; Chu, W; Du, SJ; Li, H; Rotllant, P; Schneider, M; Shen, T; Xu, J; Zhang, J1
de Lange, A; Gijsen, AP; Groen, B; Pennings, B; Senden, JM; van Loon, LJ; Zorenc, AH1
Debrabander, A; Dobbelaere, D; Farriaux, JP; Gottrand, F; Michaud, L; Turck, D; Vanderbecken, S1
Kobayashi, H; Mittendorfer, B; Sheffield-Moore, M; Volpi, E; Wolfe, RR1
WALIGORA, Z; WENDER, M1
ALLEN, RJ; HEFFELFINGER, JC; MASOTTI, RE; TSAU, MU1
O'BRIEN, D1
Bigelow, ML; Nair, KS; Proctor, DN; Short, KR; Vittone, JL1
Aarsland, A; Ferrando, AA; Paddon-Jones, D; Sheffield-Moore, M; Volpi, E; Wolf, SE; Wolfe, RR; Zhang, XJ1
Boulat, O; Boulos, M; Guignard, JP; Matthieu, JM; Van Melle, G1
Bongiovanni, A; Bostrom, J; Campos, Y; Conaway, JW; D'Azzo, A; Hahn, C; Harris, AJ; Mann, L; Nastasi, T; Rottier, R; Toy, JN1
Boirie, Y; Dardevet, D; Guillet, C; Mishellany, A; Rousset, P; Sornet, C; Zangarelli, A1
Chinkes, DL; Morio, B; Paddon-Jones, D; Sheffield-Moore, M; Volpi, E; Wolf, SE; Wolfe, RR; Yeckel, CW1
Hanley, WB1
Johnson, DE; Sellinger, OZ1
Aarsland, A; Katsanos, CS; Kobayashi, H; Sheffield-Moore, M; Wolfe, RR1
Katsanos, CS; Paddon-Jones, D; Sheffield-Moore, M; Wolfe, RR; Zhang, XJ1
Buchsbaum, MS; Sansaricq, C; Snyderman, SE; Wasserstein, MP1
Akfur, C; Ekström, F; Lundberg, S; Tunemalm, AK1
Fujita, S; Mittendorfer, B; Rasmussen, BB; Rowe, VL; Roy, M; Volpi, E; Wolfe, RR1
Gijsen, AP; Gorselink, M; Koopman, R; Manders, RJ; Pijpers, E; van Loon, LJ; Verdijk, L; Wagenmakers, AJ1
Butkevich, IP; Makukhina, GV; Mikhaĭlenko, VA1
Chinkes, DL; Cocke, TL; Paddon-Jones, D; Schutzler, SE; Symons, TB; Wolfe, RR1
Austic, RE; Lartey, FM1
Lala, R; Mussa, A; Porta, F; Spada, M1
Dhanani, S; Dillon, EL; Dreyer, HC; Drummond, MJ; Fry, CS; Pennings, B; Rasmussen, BB; Sheffield-Moore, M; Volpi, E1
Carver, MJ; Copenhaver, JH; Schain, RJ; Underdahl, NR1
Greengard, O; Isaacs, CE1
Goldspink, DF; Kelly, FJ; Lewis, SE3
Gregg, VA; Milligan, LP1
Arakawa, T; Chikaoka, H; Katsushima, N; Kobayashi, M; Minagawa, A; Saito, TG; Shioji, R1
Schneider, AJ1
Anika, SM1
Grüttner, R; Held, KR; Koepp, P; Plettner, C1
Cramer, F; Deerberg, F; Engelhardt, R; Gabius, HJ1
Bates, PC; Crie, JS; Griffin, EE; Millward, DJ; Wildenthal, K1
Hardwick, J; Hsieh, WH; Liu, DS; Richardson, A1
Butzow, JJ; Eichhorn, GL; McCool, MG1
Ardouin, P; Dhondt, JL; Farriaux, JP; Hayte, JM1
Druse, MJ; Figlewicz, DA1
Ekstrom, R; Liu, DS; Richardson, A1
Goto, S; Mizuno, D; Mori, N1
Cooke, AR; Cooke, HJ; Pfankuche, L1
Brummel, MC; Lindgren, SD; Stegink, LD; Stumbo, PJ; Wolraich, ML1
Bloomfield, PM; Fukuda, H; Hatazawa, J; Iida, H; Ito, H; Kanno, I; Miura, S; Murakami, M; Uemura, K1
Greve, J; Otto, K; Puppels, GJ; Smeets, MH; Vrensen, GF1
Kee, AJ; Smith, RC1
Abrams, SM; Heybroek, WM; Jackson, SH; Johnston, A; Maskrey, V; Puthrasingam, S; Swift, CG; Turner, P1
Chagneau, AM; Maaa, N; Peresson, R; Tesseraud, S1
Ahlrichs, JA; Denne, SC; Karn, CA; Leitch, CA; Liechty, EA; Poindexter, BB; Wang, J1
Arnold, LA; Bebin, EM; Fryburg, JS; Gunasekera, RS; Hyland, K; Jacobson, RD; Rost-Ruffner, E; Trugman, JM; Wilson, WG1
Fu, A; Nair, KS1
Denecke, J; Feldmann, R; Grenzebach, M; Pietsch, M; Sprinz, A; Ullrich, K; Weglage, J1
Mittendorfer, B; Volpi, E; Wolf, SE; Wolfe, RR1
Angelogianni, P; Schulpis, KH; Stavridis, JC; Tsakiris, S1
Arner, EC; Pratta, MA; Tortorella, MD1
Burgard, P; Schweitzer-Krantz, S1
Cipcic-Schmidt, S; Koch, R; Trefz, FK1
Brown, G; Castro, E; Deeb, SS; Edland, SD; Erkkola, R; Lee, L; Louhija, J; Martin, GM; Ogburn, CE; Oshima, J; Panduro, A; Penttinen, R; Riestra, R; Tilvis, R; Wang, L1
Tsakiris, S1
Rasmussen, BB; Sheffield-Moore, M; Volpi, E; Wolfe, RR1
Corvol, P; Kempf, H; Nishimura, H; Wideman, RF; Xi, Z; Zhang, L1
Daniels, VG; Murphy, S1
Del Valle, JA; Greengard, O1
Days, R; Harris, W; Hubert, C; Johnson, C; Stallworth, J1
Greengard, O; Sanchez-Urretia, L1
Wheatley, DN1
Dell'orco, RT; Duncan, MR1
Berry, HK; Butcher, RE; Kazmaier-Novak, KJ; Kindt, CW; Vorhees, CV1
Gilbert, BE1
Holliday, R; Stevens, A1
Daniel, PM; Moorhouse, SR; Pratt, OE1
Bozcuk, AN1
Mariotti, D; Ruscitto, R1
DeLong, R; Poplin, L1
Bielka, H; Henske, A; Schneiders, I; Venker, L1
Davison, AN; Johnson, D; Lim, L; White, J1
Kurtz, DI1
Johnson, TC; Taub, F1
Morelos, BS; Roberts, S1
Comolli, R; Delpiano, C; Schubert, AC1
Jefferson, LS; Kimball, SR; Vary, TC1
Ingram, RL; Lenham, JE; Sonntag, WE1
Hommes, FA; Moss, L1
Camacho, JA; Morgan, HE; Peterson, CJ; White, GJ1
Baillie, AG; Garlick, PJ1
Abbasi, AA; Chaudry, F; Mattson, DE; Rudman, D1
Burrin, DG; Davis, TA; Fiorotto, ML; Reeds, PJ1
Batzler, U; Schmidt, H; Ullrich, K; Wendel, U1
Batzler, U; Bickel, H; König, T; Michel, U; Schmidt, E; Schmidt, H; Trefz, FK1
Batzler, U; Benninger, C; Heusser, A; Lütcke, A; Pietz, B; Pietz, J; Sontheimer, D1
Bennett, LE; Keku, EO; Lecce, JG; Quinn, J; Rhoads, JM1
Favilli, F; Iantomasi, T; Stio, M; Treves, C; Vincenzini, MT1
Geesin, JC; Gordon, JS; Gracy, RW; Jacobson, TM; Lane, AT; Yüksel, KU1
Goldspink, DF1
Austin, BP; Menahan, LA; Sobocinski, KA1
Hommes, F; Matsuo, K; Moss, L1
Wilson, RP1
Latulippe, J; Laughrea, M1
Goto, S; Takahashi, R1
Hommes, FA; Matsuo, K1
Barron, BC; Kuck, JF; Yu, NT1
Navab, F; Winter, CG1
Hylka, VW; Meites, J; Sonntag, WE1
Carver, MJ; Copenhaver, JH; Johnson, EA; Saxton, MJ1
Nordyke, EL; Roach, MK1
Jakubiec-Puka, A; Mochnacka, I1
Johnson, RC; Shah, SN1
Rauch, H; Siegel, SJ1
Dunlop, DS; Lajtha, A; Van Elden, W1
Cristofalo, VJ; Duda, G; Ryan, JM1
Gilbert, BE; Johnson, TC2
Markiewicz, L; Weinstock, IM1
Boross, M; Pénzes, L1
Schlesinger, K; Uphouse, LL1
Pénzes, L2
Chaudhary, KD; Richard, C1
Bemiller, JN; Hoffmann, WE; Pappelis, AJ1
Cox, RA; Gökcen, M1
Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA1
Osborne, DJ; Roberts, BE1
Geison, RL; Josephson, L1
LaBella, FS1
Ibbot, FA; O'Brien, D1
Murayama, K1
Shugart, L1
Smith, BA; Waisman, HA1
Healy, PJ1
Fishman, L; Fishman, WH; Inglis, NR1
Adams, MH; Midthun, RA; Rowley, PT1
Belytschko, G; Johnson, TC1
Weber, G1
Graeber, W1
Dingley, F; Smith, JM1
Gottlieb, D; Obrig, TG1
Aoki, K; Siegel, FL1
Bodnaryk, RP1
Spadoni, MA; Ticca, M1
Beck, G; Clavert, J; Ebel, JP; Kallmeyer, MA; Prevost, C1
Holliday, R1
Fishman, WH; Ghosh, NK1
Srivastava, U1
Clarke, JT; Lowden, JA1
Mainwaring, WI1
Murthy, MR1
Fritz, RR; Rappoport, DA; Yamagami, S1
Pscheidt, GR; Tamimie, HS1

Reviews

7 review(s) available for phenylalanine and Aging

ArticleYear
Phenylketonuria, co-morbidity, and ageing: A review.
    Journal of inherited metabolic disease, 2020, Volume: 43, Issue:2

    Topics: Adult; Aged; Aging; Comorbidity; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias

2020
Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans.
    The Journal of nutrition, 2020, 08-01, Volume: 150, Issue:8

    Topics: Adult; Aged; Aging; Biological Transport; Dietary Proteins; Digestion; Female; Humans; Hyperglycemia; Male; Middle Aged; Phenylalanine

2020
[Adult phenylketonuria].
    Orvosi hetilap, 2017, Volume: 158, Issue:47

    Topics: Adult; Age Factors; Aging; Female; Health Services Accessibility; Humans; Long-Term Care; Male; Middle Aged; Phenylalanine; Phenylketonurias

2017
Adult phenylketonuria.
    The American journal of medicine, 2004, Oct-15, Volume: 117, Issue:8

    Topics: Adult; Aging; Female; Humans; Infant, Newborn; Intelligence; Phenylalanine; Phenylketonurias

2004
Biological and biochemical effects of phenylalanine analogs.
    International review of cytology, 1978, Volume: 55

    Topics: Aging; Animals; Cell Division; Enzyme Induction; Enzyme Repression; Flagella; Mutation; Neoplasms; Phenylalanine; Protein Biosynthesis; RNA; Transfer RNA Aminoacylation; Viruses

1978
Protein and amino acid requirements of fishes.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine

1986
Pyridoxine dependency and central nervous system excitability.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Acoustic Stimulation; Aging; Aminobutyrates; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Genotype; Mice; Mice, Inbred Strains; Norepinephrine; Pentylenetetrazole; Phenylalanine; Phenylalanine Hydroxylase; Physostigmine; Pyridoxine; Reserpine; Seizures; Serotonin; Tetrabenazine; Thiosemicarbazones

1972

Trials

14 trial(s) available for phenylalanine and Aging

ArticleYear
Assessment of protein requirement in octogenarian women with use of the indicator amino acid oxidation technique.
    The American journal of clinical nutrition, 2014, Volume: 99, Issue:4

    Topics: Aged, 80 and over; Aging; Body Mass Index; Breath Tests; Carbon Isotopes; Dietary Proteins; Feasibility Studies; Female; Humans; Indiana; Kinetics; National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division; Nutrition Assessment; Nutritional Requirements; Overweight; Oxidation-Reduction; Phenylalanine; Recommended Dietary Allowances; United States; White People

2014
Carbohydrate coingestion delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:6

    Topics: Aged; Aging; Blood Glucose; Dietary Carbohydrates; Dietary Proteins; Digestion; Eating; Humans; Intestinal Absorption; Male; Muscle Proteins; Phenylalanine; Postprandial Period; Young Adult

2014
No additional effect of different types of physical activity on 10-hour muscle protein synthesis in elderly men on a controlled energy- and protein-sufficient diet.
    Experimental gerontology, 2016, 06-15, Volume: 79

    Topics: Activities of Daily Living; Aged; Aging; Bed Rest; Diet; Dietary Proteins; Exercise; Humans; Insulin; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Resistance Training

2016
Whey protein ingestion in elderly persons results in greater muscle protein accrual than ingestion of its constituent essential amino acid content.
    Nutrition research (New York, N.Y.), 2008, Volume: 28, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Amino Acids, Essential; Dietary Supplements; Digestion; Female; Humans; Male; Middle Aged; Milk Proteins; Muscle Proteins; Nutritional Requirements; Phenylalanine; Whey Proteins

2008
A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects.
    Journal of the American Dietetic Association, 2009, Volume: 109, Issue:9

    Topics: Adult; Aged; Aging; Analysis of Variance; Biopsy; Carbon Isotopes; Dietary Proteins; Dose-Response Relationship, Drug; Female; Humans; Male; Meat; Muscle Proteins; Muscle, Skeletal; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine

2009
The anabolic response to resistance exercise and a protein-rich meal is not diminished by age.
    The journal of nutrition, health & aging, 2011, Volume: 15, Issue:5

    Topics: Adult; Aged; Aging; Biopsy; Dietary Proteins; Exercise; Female; Humans; Male; Meat; Muscle Proteins; Phenylalanine; Quadriceps Muscle; Resistance Training

2011
Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men.
    American journal of physiology. Endocrinology and metabolism, 2012, Apr-15, Volume: 302, Issue:8

    Topics: Aged; Aging; Algorithms; Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Digestion; Humans; Insulin; Intestinal Absorption; Kinetics; Male; Milk Proteins; Muscle Proteins; Oxidation-Reduction; Phenylalanine; Postprandial Period; Quadriceps Muscle; Tyrosine; Whey Proteins

2012
Evaluation of nutritional status and pathophysiology of growth retardation in patients with phenylketonuria.
    Journal of inherited metabolic disease, 2003, Volume: 26, Issue:1

    Topics: Aging; Anthropometry; Body Composition; Body Height; Body Weight; Child; Child, Preschool; Chromatography, Gas; Cross-Sectional Studies; Diet; Erythrocytes; Female; Growth Disorders; Hormones; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Nutritional Status; Phenylalanine; Phenylketonurias; Thyroid Hormones; Trace Elements; Tyrosine

2003
Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults.
    The American journal of clinical nutrition, 2003, Volume: 78, Issue:2

    Topics: Aged; Aging; Amino Acids, Essential; Dietary Supplements; Humans; Insulin; Muscle Proteins; Muscles; Phenylalanine

2003
Age and aerobic exercise training effects on whole body and muscle protein metabolism.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 286, Issue:1

    Topics: Adult; Aged; Aging; Body Composition; Energy Metabolism; Exercise; Female; Follow-Up Studies; Humans; Leucine; Male; Middle Aged; Muscle Proteins; Phenylalanine; Proteins; Radioactive Tracers; Reference Values

2004
Amino acid ingestion improves muscle protein synthesis in the young and elderly.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 286, Issue:3

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aging; Amino Acids, Essential; Female; Humans; Inulin; Male; Muscle Proteins; Phenylalanine

2004
Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Aging; Carbon Isotopes; Cross-Over Studies; Dietary Carbohydrates; Dietary Proteins; Double-Blind Method; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Tyrosine

2006
Phenylalanine requirement, imbalance, and dietary excess in one-week-old chicks: growth and phenylalanine hydroxylase activity.
    Poultry science, 2008, Volume: 87, Issue:2

    Topics: Aging; Animals; Chickens; Dose-Response Relationship, Drug; Male; Nutritional Requirements; Phenylalanine; Phenylalanine Hydroxylase; Weight Gain

2008
Erythrocyte L-aspartyl-L-phenylalanine hydrolase activity and plasma phenylalanine and aspartate concentrations in children consuming diets high in aspartame.
    The American journal of clinical nutrition, 1995, Volume: 62, Issue:6

    Topics: Aging; Analysis of Variance; Aspartame; Aspartic Acid; Child; Child Behavior; Child, Preschool; Cognition; Diet; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Humans; Hydrolases; Phenylalanine; Sweetening Agents

1995

Other Studies

154 other study(ies) available for phenylalanine and Aging

ArticleYear
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
    The Journal of nutrition, 2020, 05-01, Volume: 150, Issue:5

    Topics: Aged; Aging; Amino Acids; Body Weight; China; Dietary Proteins; Energy Intake; Energy Metabolism; Female; Humans; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Recommended Dietary Allowances; Tyrosine

2020
Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding.
    Nutrients, 2020, Dec-02, Volume: 12, Issue:12

    Topics: Aging; Amino Acids; Amino Acids, Essential; Dietary Supplements; Eating; Food; Humans; Kinetics; Male; Metabolism; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Postprandial Period; Protein Biosynthesis; Whey Proteins

2020
Dietary leucine requirement of older men and women is higher than current recommendations.
    The American journal of clinical nutrition, 2021, 02-02, Volume: 113, Issue:2

    Topics: Aged; Aging; Dose-Response Relationship, Drug; Female; Humans; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine

2021
Dysregulated Phenylalanine Catabolism Plays a Key Role in the Trajectory of Cardiac Aging.
    Circulation, 2021, 08-17, Volume: 144, Issue:7

    Topics: Aging; Amino Acids; Animals; Biomarkers; Biopterins; Catalysis; Cellular Senescence; Disease Models, Animal; Disease Susceptibility; Heart Diseases; Humans; Liver; Male; Mice; Mice, Knockout; Models, Biological; Myocardium; Myocytes, Cardiac; Phenylalanine; Rats

2021
The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study.
    Calcified tissue international, 2019, Volume: 105, Issue:2

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Amino Acids, Aromatic; Body Composition; Body Mass Index; Bone Density; Diet; Diet Surveys; Ethnicity; Female; Hip Fractures; Humans; Male; Multivariate Analysis; Osteoporosis; Phenylalanine; Risk; Tryptophan; Tyrosine

2019
The Phenylalanine Requirement of Elderly Men and Women Measured by Direct 13C Carbon Oxidation Method Is Similar to That of Young Adults.
    The Journal of nutrition, 2019, 10-01, Volume: 149, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Carbon Isotopes; Female; Humans; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine

2019
Protein redistribution from skeletal muscle to splanchnic tissue on fasting and refeeding in young and older healthy individuals.
    Journal of the American Medical Directors Association, 2013, Volume: 14, Issue:9

    Topics: Aged; Aging; Albumins; Body Composition; Carbon Isotopes; Eating; Fasting; Female; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Splanchnic Circulation; Young Adult

2013
The outcome of white matter abnormalities in early treated phenylketonuric patients: A retrospective longitudinal long-term study.
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:3

    Topics: Adolescent; Adult; Aging; Child; Female; Follow-Up Studies; Humans; Intelligence Tests; Longitudinal Studies; Magnetic Resonance Imaging; Male; Phenylalanine; Phenylketonurias; Retrospective Studies; White Matter; Young Adult

2015
Anabolic resistance assessed by oral stable isotope ingestion following bed rest in young and older adult volunteers: Relationships with changes in muscle mass.
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:5

    Topics: Aging; Bed Rest; Body Mass Index; Case-Control Studies; Humans; Isotopes; Magnetic Resonance Imaging; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Phenylalanine; Postprandial Period; Protein Biosynthesis; Young Adult

2017
Higher serum phenylalanine concentration is associated with more rapid telomere shortening in men.
    The American journal of clinical nutrition, 2017, Volume: 105, Issue:1

    Topics: Aged; Aging; Amino Acids; Cohort Studies; Cross-Sectional Studies; Female; Finland; Humans; Leukocytes; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Real-Time Polymerase Chain Reaction; Risk Factors; Sex Factors; Telomere; Telomere Shortening

2017
alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:7

    Topics: Aging; Animals; Antioxidants; Blotting, Western; Body Composition; Calorimetry, Indirect; Cell Line; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Energy Metabolism; Fatty Acids; Glucose Tolerance Test; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Thioctic Acid; Trans-Activators; Transcription Factors

2010
The use of prealbumin concentration as a biomarker of nutritional status in treated phenylketonuric patients.
    Annals of nutrition & metabolism, 2010, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aging; Biomarkers; Child; Child, Preschool; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Intake; Female; Humans; Infant; Male; Nutritional Status; Phenylalanine; Phenylketonurias; Prealbumin; Young Adult

2010
Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:1

    Topics: Activating Transcription Factor 4; Active Transport, Cell Nucleus; Adult; Age Factors; Aged; Aging; Amino Acid Transport Systems; Amino Acids; Analysis of Variance; Biopsy; Blotting, Western; Eukaryotic Initiation Factor-2; Female; Gene Expression Regulation; Humans; Leucine; Male; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Muscle Contraction; Phenylalanine; Phosphorylation; Polymerase Chain Reaction; Quadriceps Muscle; Resistance Training; Ribosomal Protein S6; RNA, Messenger; STAT3 Transcription Factor; Time Factors; TOR Serine-Threonine Kinases

2011
Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:5

    Topics: Adult; Age Factors; Aged; Aging; Amino Acids; Biopsy; Blood Flow Velocity; Blood Glucose; Female; Humans; Hyperemia; Infusions, Intra-Arterial; Infusions, Intravenous; Insulin; Lower Extremity; Male; Microcirculation; Microdialysis; Muscle Proteins; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Phenylalanine; Regional Blood Flow; Time Factors

2011
Smyd1b_tv1, a key regulator of sarcomere assembly, is localized on the M-line of skeletal muscle fibers.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Aging; Alternative Splicing; Amino Acid Sequence; Animals; Cell Differentiation; Embryo, Nonmammalian; Gene Knockdown Techniques; Green Fluorescent Proteins; Histone-Lysine N-Methyltransferase; HSP90 Heat-Shock Proteins; Molecular Sequence Data; Muscle Development; Muscle Fibers, Skeletal; Mutagenesis, Insertional; Myofibrils; Phenylalanine; Protein Isoforms; Protein Transport; Recombinant Fusion Proteins; Sarcomeres; Serine; Subcellular Fractions; Time Factors; Zebrafish; Zebrafish Proteins

2011
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine

1964
PHENYLALANINE HYDROXYLASE ACTIVITY IN NEWBORN INFANTS.
    Pediatrics, 1964, Volume: 33

    Topics: Aging; Black People; Blood Chemical Analysis; Carrier State; Clinical Laboratory Techniques; Diet; Genetics, Medical; Humans; Infant; Infant, Newborn; Laboratories; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Urine; White People

1964
THE RELATION OF THE FREE PHENYLALANINE CONTENT OF MOUSE BRAIN TO AGE: ITS POSSIBLE SIGNIFICANCE IN PHENYLKETONURIA.
    Journal of mental deficiency research, 1964, Volume: 8

    Topics: Aging; Amino Acids; Animals; Biochemical Phenomena; Brain; Brain Chemistry; Mice; Nitrogen; Phenylalanine; Phenylketonurias; Research

1964
Correlation between plasma and urine phenylalanine concentrations.
    Biology of the neonate, 2004, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Humans; Infant; Intellectual Disability; Phenylalanine; Phenylketonurias; Pilot Projects

2004
Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.
    Developmental cell, 2004, Volume: 6, Issue:2

    Topics: Aging; Animals; beta Catenin; Blotting, Northern; Blotting, Western; Cells, Cultured; Cytoskeletal Proteins; Embryo, Mammalian; Epoxy Compounds; Gene Expression Regulation, Developmental; Heart; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Knockout; Microscopy, Electron; Muscle Development; Muscle, Skeletal; Mutation; Myoblasts; Myogenin; Phenylalanine; Precipitin Tests; Repressor Proteins; Sarcomeres; Staining and Labeling; Subcellular Fractions; Tenascin; Trans-Activators; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Ubiquitins

2004
Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle.
    Experimental gerontology, 2004, Volume: 39, Issue:5

    Topics: Aging; Alanine; Animals; Diet; Leucine; Male; Mitochondrial Proteins; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; Phenylalanine; Rats; Rats, Wistar; Sarcoplasmic Reticulum

2004
Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:3

    Topics: Adult; Aged; Aging; Exercise; Fibrinogen; Humans; Male; Muscle Proteins; Osmolar Concentration; Phenylalanine; Regional Blood Flow; Serum Albumin

2004
Age-dependent utilization of phenylalanine for the synthesis of neuronal and glial proteins.
    Neurobiology, 1973, Volume: 3, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Injections; Male; Nerve Tissue Proteins; Neuroglia; Neurons; Phenylalanine; Rats; Rats, Sprague-Dawley

1973
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:5

    Topics: Adult; Age Factors; Aged; Aging; Amino Acids, Essential; Area Under Curve; Deuterium; Female; Humans; Infusions, Intravenous; Leg; Male; Muscle Proteins; Phenylalanine; Postprandial Period; Regional Blood Flow

2005
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein.
    Experimental gerontology, 2006, Volume: 41, Issue:2

    Topics: Administration, Oral; Aged; Aging; Amino Acids; Analysis of Variance; Female; Humans; Leg; Male; Milk Proteins; Muscle Proteins; Phenylalanine; Regional Blood Flow; Whey Proteins

2006
Cerebral glucose metabolism in adults with early treated classic phenylketonuria.
    Molecular genetics and metabolism, 2006, Volume: 87, Issue:3

    Topics: Adult; Aging; Case-Control Studies; Cerebral Cortex; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Phenylalanine; Phenylketonurias; Pilot Projects; Positron-Emission Tomography; Time Factors

2006
Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase.
    Biochemistry, 2006, Jan-10, Volume: 45, Issue:1

    Topics: Acetylcholinesterase; Aging; Animals; Binding Sites; Catalysis; Cholinesterase Inhibitors; Histidine; Humans; Mice; Molecular Conformation; Organophosphates; Organophosphorus Compounds; Phenylalanine; Water

2006
Insulin resistance of muscle protein metabolism in aging.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:6

    Topics: Adult; Aged; Aging; Blood Flow Velocity; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Leg; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine

2006
[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:2

    Topics: Aging; Analgesics; Animals; Female; Inflammation; Male; Ondansetron; Pain; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Stress, Physiological

2007
Aging does not impair the anabolic response to a protein-rich meal.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:2

    Topics: Adipose Tissue; Adult; Aged; Aging; Amino Acids; Amino Acids, Essential; Body Mass Index; Carbon Isotopes; Dietary Proteins; Female; Humans; Infusions, Intravenous; Male; Meat; Middle Aged; Phenylalanine

2007
Phalangeal quantitative ultrasound in children with phenylketonuria: a pilot study.
    Ultrasound in medicine & biology, 2008, Volume: 34, Issue:7

    Topics: Adult; Aging; Body Mass Index; Cross-Sectional Studies; Female; Finger Phalanges; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Pilot Projects; Ultrasonography

2008
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:5

    Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blotting, Western; Extracellular Signal-Regulated MAP Kinases; Glucose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hormones; Humans; Hydrocortisone; Lactic Acid; Leucine; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Phosphorylation; Physical Fitness; Protein Kinases; RNA; Signal Transduction; TOR Serine-Threonine Kinases

2008
Protein metabolism in the developing brain: influence of birth and gestational age.
    Science (New York, N.Y.), 1967, May-19, Volume: 156, Issue:3777

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Diseases; Carbon Isotopes; Nerve Tissue Proteins; Phenylalanine; Swine

1967
The effect of hyperphenylalaninaemia on glycine metabolism in developing rat brain.
    The Biochemical journal, 1980, Nov-15, Volume: 192, Issue:2

    Topics: Aging; Amino Acids; Animals; Brain; Glycine; Neurotransmitter Agents; Phenylalanine; Rats; Serotonin

1980
Pre- and post-natal growth and protein turnover in smooth muscle, heart and slow- and fast-twitch skeletal muscles of the rat.
    The Biochemical journal, 1984, Jan-15, Volume: 217, Issue:2

    Topics: Aging; Animals; DNA; Heart; Male; Muscle Development; Muscle Proteins; Muscle, Smooth; Muscles; Myocardium; Phenylalanine; Rats; Rats, Inbred Strains; RNA

1984
Protein synthesis during the developmental growth of the small and large intestine of the rat.
    The Biochemical journal, 1984, Jan-15, Volume: 217, Issue:2

    Topics: Aging; Animals; DNA; Intestinal Mucosa; Intestine, Large; Intestine, Small; Male; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA

1984
In vitro energy costs of Na+, K+ATPase activity and protein synthesis in muscle from calves differing in age and breed.
    The British journal of nutrition, 1982, Volume: 48, Issue:1

    Topics: Aging; Animals; Cattle; Culture Techniques; Male; Muscle Proteins; Muscles; Oxygen Consumption; Phenylalanine; Sodium-Potassium-Exchanging ATPase; Species Specificity; Tyrosine

1982
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
    The Tohoku journal of experimental medicine, 1982, Volume: 137, Issue:1

    Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine

1982
Newborn phenylalanine/tyrosine metabolism. Implications for screening for phenylketonuria.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:5

    Topics: Aging; Fetal Blood; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine

1983
Ontogeny of cholecystokinin satiety in rats.
    European journal of pharmacology, 1983, May-06, Volume: 89, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Cholecystokinin; Feeding Behavior; Female; Male; Phenylalanine; Rats; Stereoisomerism

1983
Plasma amino acid pattern at noon in early treated hyperphenylalaninemic, phenylketonuric, and normal children.
    Annals of nutrition & metabolism, 1983, Volume: 27, Issue:4

    Topics: Adolescent; Aging; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Female; Glutamine; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Time Factors

1983
Age-related changes in different steps of protein synthesis of liver and kidney of rats.
    FEBS letters, 1983, Aug-22, Volume: 160, Issue:1-2

    Topics: Aging; Animals; Kidney; Kinetics; Liver; Male; Methionine; Organ Specificity; Phenylalanine; Protein Biosynthesis; Proteins; Puromycin; Rats; Rats, Inbred Strains

1983
Age-related alterations in cardiac protein turnover.
    Journal of molecular and cellular cardiology, 1981, Volume: 13, Issue:6

    Topics: Aging; Animals; Heart; In Vitro Techniques; Insulin; Kinetics; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Tyrosine

1981
Cell-free protein synthesis by kidney from the aging female Fischer F344 rat.
    Biochimica et biophysica acta, 1981, Jan-29, Volume: 652, Issue:1

    Topics: Aging; Animals; Cell-Free System; Female; Kidney; Magnesium; Microsomes; Phenylalanine; Poly U; Potassium; Protein Biosynthesis; Rats; Rats, Inbred F344; Ribonucleases; Ribosomes; Valine

1981
Does the capacity of ribosomes to control translation fidelity change with age?
    Mechanisms of ageing and development, 1981, Volume: 15, Issue:2

    Topics: Aging; Animals; Dose-Response Relationship, Drug; Leucine; Magnesium; Male; Paromomycin; Peptide Chain Elongation, Translational; Phenylalanine; Poly U; Rats; Ribosomes

1981
Developmental aspects of pteridine metabolism and relationships with phenylalanine metabolism.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Oct-26, Volume: 116, Issue:2

    Topics: Adolescent; Adult; Aging; Amniotic Fluid; Animals; Biopterins; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neopterin; Phenylalanine; Phenylketonurias; Pregnancy; Pteridines; Rats; Rats, Inbred Strains

1981
Experimental hyperphenylalaninemia: effect on central nervous system myelin subfractions.
    Experimental neurology, 1980, Volume: 67, Issue:2

    Topics: Aging; Brain; Glucose; Glycine; Myelin Proteins; Myelin Sheath; Nerve Tissue Proteins; Phenylalanine

1980
Changes in brain protein synthesis during the life span of male Fischer rats.
    Gerontology, 1980, Volume: 26, Issue:3

    Topics: Aging; Animals; Brain; Cell-Free System; DNA; Leucine; Male; Nerve Tissue Proteins; Phenylalanine; Rats; Ribosomes; RNA

1980
Translational activity and fidelity of purified ribosomes from aging mouse livers.
    Advances in experimental medicine and biology, 1980, Volume: 129

    Topics: Aging; Animals; In Vitro Techniques; Leucine; Liver; Mice; Phenylalanine; Protein Biosynthesis; RNA, Ribosomal

1980
Tryptophan transport by isolated newborn rabbit jejunum.
    The American journal of physiology, 1980, Volume: 239, Issue:4

    Topics: Aging; Alanine; Animals; Animals, Newborn; Intestinal Absorption; Jejunum; Phenylalanine; Rabbits; Sodium; Tryptophan

1980
Aging effect on neutral amino acid transport at the blood-brain barrier measured with L-[2-18F]-fluorophenylalanine and PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:7

    Topics: Adult; Aged; Aging; Amino Acids; Biological Transport; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Phenylalanine; Tomography, Emission-Computed

1995
Local variations in protein structure in the human eye lens: a Raman microspectroscopic study.
    Biochimica et biophysica acta, 1993, Aug-07, Volume: 1164, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Microchemistry; Middle Aged; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Tyrosine

1993
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:8

    Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine

1993
Aspartame pharmacokinetics - the effect of ageing.
    Age and ageing, 1996, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartame; Female; Humans; Male; Metabolic Clearance Rate; Phenylalanine; Pilot Projects; Reference Values

1996
Relative responses of protein turnover in three different skeletal muscles to dietary lysine deficiency in chicks.
    British poultry science, 1996, Volume: 37, Issue:3

    Topics: Aging; Analysis of Variance; Animal Feed; Animals; Chickens; Diet; Lysine; Male; Muscle Development; Muscle, Skeletal; Organ Size; Organ Specificity; Phenylalanine; Protein Biosynthesis; Tritium

1996
Amino acids suppress proteolysis independent of insulin throughout the neonatal period.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 1

    Topics: Aging; Amino Acids; Blood Glucose; Humans; Hydroxylation; Infant, Newborn; Infusions, Intravenous; Insulin; Leucine; Osmolar Concentration; Oxidation-Reduction; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Tyrosine

1997
Oral phenylalanine loading in dopa-responsive dystonia: a possible diagnostic test.
    Neurology, 1997, Volume: 48, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biopterins; Child, Preschool; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female; Humans; Male; Middle Aged; Neopterin; Osmolar Concentration; Phenylalanine; Time Factors; Tyrosine

1997
Age effect on fibrinogen and albumin synthesis in humans.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Adult; Aged; Aging; Female; Fibrinogen; Humans; Keto Acids; Leucine; Male; Middle Aged; Osmolar Concentration; Phenylalanine; Protein Precursors; Serum Albumin

1998
Regression of neuropsychological deficits in early-treated phenylketonurics during adolescence.
    Journal of inherited metabolic disease, 1999, Volume: 22, Issue:6

    Topics: Adolescent; Aging; Central Nervous System Diseases; Child; Female; Humans; Intelligence; Longitudinal Studies; Male; Mental Disorders; Motor Skills; Phenylalanine; Phenylketonurias

1999
Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction.
    The American journal of physiology, 1999, Volume: 277, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aging; Amino Acids; Female; Humans; Kinetics; Male; Models, Biological; Muscle Proteins; Phenylalanine; Splanchnic Circulation

1999
Protective effect of L-phenylalanine on rat brain acetylcholinesterase inhibition induced by free radicals.
    Clinical biochemistry, 2000, Volume: 33, Issue:2

    Topics: Acetylcholinesterase; Aging; Animals; Ascorbic Acid; Brain; Cholinesterase Inhibitors; Female; Ferric Compounds; Ferrous Compounds; Free Radicals; Frontal Lobe; Hippocampus; Hydrogen Peroxide; Hypothalamus; Kinetics; Male; Phenylalanine; Pituitary Gland; Rats; Rats, Wistar

2000
Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Age Factors; Aggrecans; Aging; Alanine; Animals; beta-Galactosidase; Blotting, Western; Cattle; Chondroitin Sulfates; Chondroitinases and Chondroitin Lyases; Endopeptidases; Extracellular Matrix Proteins; Freezing; Glutamine; Glycosaminoglycans; Glycoside Hydrolases; Glycosylation; Keratan Sulfate; Lectins, C-Type; Matrix Metalloproteinase 3; Phenylalanine; Proteoglycans; Serine; Time Factors

2000
Survey of national guidelines for the treatment of phenylketonuria.
    European journal of pediatrics, 2000, Volume: 159 Suppl 2

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Data Collection; Europe; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Practice Guidelines as Topic; Time Factors; United States

2000
Final intelligence in late treated patients with phenylketonuria.
    European journal of pediatrics, 2000, Volume: 159 Suppl 2

    Topics: Adult; Aging; Humans; Intelligence; Phenylalanine; Phenylketonurias; Regression Analysis; Retrospective Studies; Stanford-Binet Test; Time Factors; Wechsler Scales

2000
Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.
    American journal of medical genetics, 2000, Dec-11, Volume: 95, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Substitution; Arginine; Arteriosclerosis; Coronary Artery Disease; Cysteine; Finland; Gene Frequency; Genotype; Haplotypes; Humans; Infant, Newborn; Leucine; Longevity; Mexico; Middle Aged; Phenylalanine; Polymorphism, Genetic; Werner Syndrome

2000
Effects of L-phenylalanine on acetylcholinesterase and Na(+), K(+)-ATPase activities in adult and aged rat brain.
    Mechanisms of ageing and development, 2001, Apr-30, Volume: 122, Issue:5

    Topics: Acetylcholinesterase; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Eels; Female; Male; Phenoxybenzamine; Phenylalanine; Propranolol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2001
Basal muscle amino acid kinetics and protein synthesis in healthy young and older men.
    JAMA, 2001, Sep-12, Volume: 286, Issue:10

    Topics: Adult; Aged; Aging; Amino Acids; Basal Metabolism; Biopsy, Needle; Catheterization, Peripheral; Cross-Sectional Studies; Humans; Indocyanine Green; Kinetics; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Proteins; Testosterone

2001
Maturation-dependent neointima formation in fowl aorta.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2001, Volume: 130, Issue:1

    Topics: Actins; Aging; Animals; Aorta, Abdominal; Arginine; Asparagine; Blood Pressure; Chickens; Cholesterol; Female; Hyperplasia; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nitric Oxide; Ornithine; Phenylalanine; Tunica Intima

2001
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
    Journal of developmental physiology, 1979, Volume: 1, Issue:2

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine

1979
Isoenzyme composition of hepatic phenylalanine hydroxylase in developing rats after treatment with cortisol, alpha-methylphenylalanine and p-chlorophenylalanine in vivo.
    Biochemical medicine, 1978, Volume: 20, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Fenclonine; Fetus; Hydrocortisone; Isoenzymes; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats

1978
Studies on avian heart pyruvate kinase during development.
    Biochemical and biophysical research communications, 1977, Apr-25, Volume: 75, Issue:4

    Topics: Adenosine Triphosphate; Aging; Alanine; Animals; Chickens; Diphosphates; Heart; Kinetics; Myocardium; Phenylalanine; Pyruvate Kinase

1977
Phenylalanine-pyruvate aminotransferase in immature and adult mammalian tissues. Induction in fetal rat liver.
    Biochimica et biophysica acta, 1977, May-26, Volume: 497, Issue:3

    Topics: Adult; Aging; Animals; Brain; Carcinoma, Hepatocellular; Enzyme Induction; Female; Fetus; Gestational Age; Humans; Liver; Liver Neoplasms; Lung; Neoplasms, Experimental; Organ Specificity; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Pyruvates; Rats; Species Specificity; Structure-Activity Relationship; Transaminases

1977
Effects of the incorporation of p-fluorophenylalanine on the in vitro lifespan of human diploid cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 161, Issue:4

    Topics: Aging; Cell Division; Cell Survival; Cells, Cultured; Diploidy; Fibroblasts; Glucosephosphate Dehydrogenase; Hot Temperature; Humans; p-Fluorophenylalanine; Phenylalanine; Time Factors

1979
Induced PKU in rats: effects of age and melatonin treatment.
    Pharmacology, biochemistry, and behavior, 1977, Volume: 7, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Humans; Learning; Melatonin; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Time Factors; Tyrosine

1977
Ribosomal activity in prenatal mouse brain.
    Journal of neurochemistry, 1978, Volume: 31, Issue:1

    Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Animals, Newborn; Brain; Female; Mice; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Ribosomes

1978
The effect of an amino acid analogue, p-fluorophenylalanine, on longevity of mice.
    Gerontology, 1978, Volume: 24, Issue:6

    Topics: Aging; Animals; Body Weight; Diet; Female; Longevity; Male; Mice; Mice, Inbred CBA; p-Fluorophenylalanine; Phenylalanine; Proteins

1978
Post-natal changes in the transport of aromatic amino acids into the brain [proceedings].
    The Journal of physiology, 1978, Volume: 284

    Topics: Aging; Amino Acids; Animals; Biological Transport; Brain; Phenylalanine; Rats; Tryptophan; Tyrosine

1978
Testing the protein error hypothesis of ageing in Drosophila.
    Experimental gerontology, 1976, Volume: 11, Issue:3-4

    Topics: Aging; Animals; Drosophila melanogaster; Ethionine; Half-Life; Male; Phenylalanine; Proteins; Tryptophan; Tyrosine

1976
Age-related changes of accuracy and efficiency of protein synthesis machinery in rat.
    Biochimica et biophysica acta, 1977, Mar-02, Volume: 475, Issue:1

    Topics: Aging; Animals; Carbon Radioisotopes; Isotope Labeling; Kinetics; Leucine; Liver; Phenylalanine; Poly U; Protein Biosynthesis; Rats; Ribosomes; Tritium

1977
On the etiology of aging.
    Journal of theoretical biology, 1977, Jul-07, Volume: 67, Issue:1

    Topics: Aging; Amino Acids; Aspartic Acid; Half-Life; Humans; Isomerism; Phenylalanine; Proteins; Thermodynamics

1977
[Age dependent changes of biosynthesis of proteins (author's transl)].
    Zeitschrift fur Alternsforschung, 1976, Volume: 31, Issue:1

    Topics: Aging; Animals; Cytosol; Kidney; Liver; Phenylalanine; Poly U; Protein Biosynthesis; Rats; Ribosomal Proteins; RNA, Ribosomal

1976
The effect of experimental hyperphenylalaninaemia on polyribosomes of the developing rat brain.
    Biochemical Society transactions, 1975, Volume: 3, Issue:1

    Topics: Aging; Animals; Brain; Phenylalanine; Polyribosomes; Rats; Ultracentrifugation

1975
The effect of ageing on in vitro fidelity of translation in mouse liver.
    Biochimica et biophysica acta, 1975, Nov-04, Volume: 407, Issue:4

    Topics: Aging; Animals; Leucine; Liver; Magnesium; Mice; Microsomes, Liver; Phenylalanine; Poly U; Protein Biosynthesis

1975
The mechanism of polyribosome disaggregation in brain tissue by phenylalanine.
    The Biochemical journal, 1975, Volume: 151, Issue:1

    Topics: Aging; Animals; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Mice; Phenylalanine; Polyribosomes; Potassium Chloride; Ribosomal Proteins; Ribosomes

1975
Role of ribonuclease action in phenylalanine-induced disaggregation of rat cerebral polyribosomes.
    Journal of neurochemistry, 1976, Volume: 26, Issue:2

    Topics: Aging; Amino Acids; Animals; Binding Sites; Brain; Cell Fractionation; Kinetics; Liver; Male; Nerve Tissue Proteins; Organ Specificity; Phenylalanine; Polyribosomes; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes

1976
Dependency on the source of supernatant factors for optimal 14C-polyphenylalanine synthesis by high-salt wash treated liver ribosomal subunits in rats of different ages.
    Experimental gerontology, 1976, Volume: 11, Issue:1-2

    Topics: Aging; Animals; In Vitro Techniques; Liver; Male; Peptide Biosynthesis; Peptides; Phenylalanine; Potassium Chloride; Protein Biosynthesis; Rats; Ribosomes

1976
Age-dependent decrease in the amount of eukaryotic initiation factor 2 in various rat tissues.
    The Biochemical journal, 1992, Aug-15, Volume: 286 ( Pt 1)

    Topics: Aging; Animals; Brain; Eukaryotic Initiation Factor-2; Kidney; Liver; Lung; Male; Organ Size; Organ Specificity; Phenylalanine; Protein Biosynthesis; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Spleen; Tritium

1992
Effects of aging and dietary restriction on tissue protein synthesis: relationship to plasma insulin-like growth factor-1.
    Journal of gerontology, 1992, Volume: 47, Issue:5

    Topics: Aging; Animals; Diaphragm; Diet; Insulin-Like Growth Factor I; Liver; Male; Mice; Mice, Inbred C57BL; Myocardium; Phenylalanine; Protein Biosynthesis; Specific Pathogen-Free Organisms; Time Factors; Tissue Distribution; Tyrosine

1992
Myelin turnover in hyperphenylalaninaemia. A re-evaluation with the HPH-5 mouse.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:2

    Topics: Aging; Amino Acids; Animals; Body Weight; Brain; Half-Life; Mice; Mice, Mutant Strains; Myelin Proteins; Myelin Sheath; Organ Size; Phenylalanine; Phenylalanine Hydroxylase

1992
Accelerated ribosome formation and growth in neonatal pig hearts.
    The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Cell Fractionation; Centrifugation, Density Gradient; Heart; Heart Ventricles; Myocardium; Phenylalanine; Protein Biosynthesis; Ribosomes; RNA; Swine

1990
Protein synthesis in adult skeletal muscle after tenotomy: responses to fasting and insulin infusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: Aging; Animals; Blood Glucose; Fasting; Female; Hindlimb; Insulin; Muscle Proteins; Muscles; Phenylalanine; Rats; Ribosomes; RNA; Tendons

1991
Delayed plasma clearance of phenylalanine and tyrosine in elderly men.
    Journal of the American Geriatrics Society, 1991, Volume: 39, Issue:1

    Topics: Adult; Aged; Aging; Amino Acids; Dementia; Enteral Nutrition; Humans; Middle Aged; Phenylalanine; Tyrosine

1991
Stage of development and fasting affect protein synthetic activity in the gastrointestinal tissues of suckling rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:7

    Topics: Aging; Animals; Animals, Suckling; Chromatography, High Pressure Liquid; Fasting; Gastric Mucosa; Intestine, Small; Pancreas; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains

1991
Six-year follow up of phenylalanine intakes and plasma phenylalanine concentrations.
    European journal of pediatrics, 1990, Volume: 149 Suppl 1

    Topics: Aging; Female; Follow-Up Studies; Humans; Infant, Newborn; Male; Patient Compliance; Phenylalanine; Phenylketonurias

1990
Significance of the in vivo deuterated phenylalanine load for long-term phenylalanine tolerance and psycho-intellectual outcome in patients with PKU.
    European journal of pediatrics, 1990, Volume: 149 Suppl 1

    Topics: Aging; Humans; Infant, Newborn; Intelligence Tests; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Prospective Studies

1990
EEG development in early treated PKU patients from birth to 6 years of age.
    European journal of pediatrics, 1990, Volume: 149 Suppl 1

    Topics: Aging; Electroencephalography; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias

1990
Development of L-glutamine-stimulated electroneutral sodium absorption in piglet jejunum.
    The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Chlorides; Electric Conductivity; Electrophysiology; Glutamine; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mannitol; Muscle Development; Muscle, Smooth; Phenylalanine; Sodium; Swine

1990
Changes in metabolite transport by small intestine and kidney of young and old rats.
    Mechanisms of ageing and development, 1990, Mar-15, Volume: 52, Issue:2-3

    Topics: Aging; Animals; Aspartic Acid; Citrates; Citric Acid; Glucose; In Vitro Techniques; Intestine, Small; Kidney Cortex; Male; Microvilli; Phenylalanine; Rats; Rats, Inbred Strains

1990
Effects of aging and xerosis on the amino acid composition of human skin.
    The Journal of investigative dermatology, 1990, Volume: 95, Issue:3

    Topics: Aging; Amino Acids; Female; Filaggrin Proteins; Glycine; Humans; Ichthyosis; Leucine; Phenylalanine; Skin; Tyrosine

1990
Protein turnover and growth of the rat brain from the foetus to old age.
    Journal of neurochemistry, 1988, Volume: 50, Issue:5

    Topics: Aging; Animals; Brain; DNA; Female; Fetus; Kinetics; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Rats; RNA

1988
Characterization of elevated plasma alkaline phosphatase activity in genetically obese mice.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:3

    Topics: Aging; Alkaline Phosphatase; Animals; Drug Interactions; Homoarginine; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Obesity; Phenylalanine

1985
Development of adenosine 5'-triphosphate sulfurylase and adenosine phosphosulfate kinase in rat cerebrum and liver.
    Developmental neuroscience, 1987, Volume: 9, Issue:2

    Topics: Aging; Animals; Brain; Liver; Nucleotidyltransferases; Phenylalanine; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Inbred Strains; Sulfate Adenylyltransferase

1987
The poly(U) translational capacity of Fischer 344 rat liver does not deteriorate with age and is not affected by dietary regime.
    Mechanisms of ageing and development, 1988, Nov-14, Volume: 45, Issue:2

    Topics: Aging; Animals; Diet; In Vitro Techniques; Liver; Male; Phenylalanine; Poly U; Protein Biosynthesis; Rats; Rats, Inbred F344; Ribosomes

1988
Fidelity of aminoacylation by rat-liver tyrosyl-tRNA synthetase. Effect of age.
    European journal of biochemistry, 1988, Dec-15, Volume: 178, Issue:2

    Topics: Acylation; Age Factors; Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Binding, Competitive; Biological Transport; Electrophoresis, Polyacrylamide Gel; Liver; Male; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred F344; RNA, Transfer; Tyrosine; Tyrosine-tRNA Ligase

1988
The development of the muscarinic acetylcholine receptor in normal and hyperphenylalaninemic rat cerebrum.
    Neurochemical research, 1988, Volume: 13, Issue:9

    Topics: Aging; Animals; Brain; Phenylalanine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic

1988
Raman spectroscopic evaluation of aging and long-wave UV exposure in the guinea pig lens: a possible model for human aging.
    Experimental eye research, 1988, Volume: 46, Issue:2

    Topics: Aging; Animals; Disulfides; Guinea Pigs; Lens, Crystalline; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Sulfhydryl Compounds; Tryptophan; Tyrosine; Ultraviolet Rays

1988
Effect of aging on intestinal absorption of aromatic amino acids in vitro in the rat.
    The American journal of physiology, 1988, Volume: 254, Issue:4 Pt 1

    Topics: Aging; Animals; In Vitro Techniques; Intestinal Absorption; Jejunum; Kinetics; Male; Phenylalanine; Rats; Rats, Inbred F344; Tryptophan; Tyrosine

1988
Growth hormone restores protein synthesis in skeletal muscle of old male rats.
    Journal of gerontology, 1985, Volume: 40, Issue:6

    Topics: Age Factors; Aging; Animals; Diaphragm; Growth Hormone; Levodopa; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains

1985
Protein turnover and cathepsin B activity in several individual tissues of foetal and senescent rats.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1985, Volume: 82, Issue:4

    Topics: Aging; Animals; Cathepsin B; Cathepsins; Female; Fetus; Gestational Age; Male; Phenylalanine; Pregnancy; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium

1985
Effect of para-chlorophenylalanine on the growth and development of the fetal, neonatal, and adult rat.
    Biochemical medicine, 1970, Volume: 4, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Feeding Behavior; Female; Fenclonine; Fetus; Gestational Age; Male; Organ Size; Phenylalanine; Pregnancy; Rats; Time Factors

1970
Effect of p-chlorophenylalanine and L-phenylalanine on deoxyribonucleic acid and protein content of developing rat cerebellum.
    Biochemical pharmacology, 1974, Oct-15, Volume: 23, Issue:20

    Topics: Aging; Animals; Body Weight; Brain Chemistry; Cerebellum; DNA; Female; Fenclonine; Nerve Tissue Proteins; Phenylalanine; Rats; Time Factors

1974
Activity of the phenylalanine hydroxylating system in liver of newborn, suckling and adult rats.
    Acta biochimica Polonica, 1969, Volume: 16, Issue:4

    Topics: Aging; Aldehydes; Animals; Animals, Newborn; Body Weight; Carbon Isotopes; Female; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; Organ Size; Phenylalanine; Proteins; Rats; Tyrosine

1969
Effect of hyperphenylalaninemia on fatty acid composition of lipids of rat brain myelin.
    Journal of neurochemistry, 1973, Volume: 21, Issue:5

    Topics: Aging; Aldehydes; Animals; Brain Chemistry; Cerebrosides; Chromatography, Gas; Chromatography, Thin Layer; Esters; Fatty Acids; Glycolipids; Lipids; Myelin Sheath; Nerve Tissue Proteins; Phenylalanine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingolipids; Sphingomyelins; Time Factors

1973
Aromatic amino acid metabolism in the wabbler-lethal mouse.
    Biochemical genetics, 1969, Volume: 2, Issue:4

    Topics: Aging; Animals; Liver; Mice; Mixed Function Oxygenases; Nervous System Diseases; Phenylalanine; Rodent Diseases; Transaminases; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase

1969
Measurements of rates of protein synthesis in rat brain slices.
    Journal of neurochemistry, 1974, Volume: 22, Issue:5

    Topics: Aging; Amino Acids; Animals; Brain; Carbon Radioisotopes; Histidine; In Vitro Techniques; Kinetics; Leucine; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Time Factors; Tritium; Valine

1974
Error accumulation and aging in human diploid cells.
    Journal of gerontology, 1974, Volume: 29, Issue:6

    Topics: Aging; Carbon Radioisotopes; Cell Division; Cell Line; Cells, Cultured; Culture Media; Depression, Chemical; Diploidy; DNA; Dose-Response Relationship, Drug; Ethionine; Humans; Hydrocarbons, Fluorinated; Lung; Macromolecular Substances; Phenylalanine; Protein Biosynthesis

1974
Fetal development: the effects of maturation on in vitro protein synthesis by mouse brain tissue.
    Journal of neurochemistry, 1974, Volume: 23, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Arginine; Brain; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Deoxycholic Acid; Female; Fetus; Gestational Age; In Vitro Techniques; Magnesium; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phenylalanine; Polyribosomes; Pregnancy; Time Factors

1974
Muscle protein synthesis during development of the normal and dystrophic chicken. Activity of supernatant elongation factors.
    Biochimica et biophysica acta, 1974, Dec-06, Volume: 374, Issue:2

    Topics: Acyltransferases; Aging; Animals; Carbon Radioisotopes; Chick Embryo; Chickens; Chromatography, Ion Exchange; Cytosol; Ethylmaleimide; Hydroxyapatites; Leucine; Muscle Development; Muscle Proteins; Muscles; Muscular Dystrophy, Animal; Peptide Elongation Factors; Phenylalanine; Ribosomes; RNA, Transfer; Spectrophotometry, Ultraviolet; Time Factors; Transfer RNA Aminoacylation

1974
Intestinal absorption of some heterocyclic and aromatic amino acids from the ageing gut.
    Experimental gerontology, 1974, Volume: 9, Issue:5-6

    Topics: Aging; Animals; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver; Organ Size; Phenylalanine; Proline; Rats; Tryptophan

1974
The use of aminoacyl-tRNA to measure polypeptide synthesis by ribosomes isolated from neonatal and adult mouse brain tissue.
    Biochemical and biophysical research communications, 1972, Mar-24, Volume: 46, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Anti-Bacterial Agents; Brain; Diphtheria Toxin; Escherichia coli; Ethylmaleimide; Fusidic Acid; Mice; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptides; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Tritium; Uracil Nucleotides

1972
Intestinal absorption of aromatic amino acids in senescence.
    Revue roumaine de medecine interne (1964), 1972, Volume: 9, Issue:2

    Topics: Aging; Amino Acids; Animals; Indicator Dilution Techniques; Intestinal Absorption; Phenylalanine; Protein-Losing Enteropathies; Rats; Tryptophan

1972
[Some aspects of protein synthesis in the thoracic muscles in the development of Schistocerca gregaria (Forsk.)].
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:11

    Topics: Aging; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cycloheximide; Grasshoppers; Guanosine Triphosphate; Larva; Microsomes; Muscle Proteins; Muscles; Pancreas; Phenylalanine; Poly U; Polyribosomes; Puromycin; Ribonucleases; RNA; Stimulation, Chemical; Thorax; Trypsin

1972
[Amino acid absorption in the aged].
    Zeitschrift fur Alternsforschung, 1973, Volume: 26, Issue:4

    Topics: Age Factors; Aging; Amino Acids; Animals; Carbohydrate Metabolism; Female; Intestinal Absorption; Phenylalanine; Rats; Tryptophan; Vitamins

1973
Relationship of protein metabolism to senescence of corn (Zea mays L.) stalk parenchyma, cob parenchyma and first developed leaf tissues.
    Mechanisms of ageing and development, 1973, Volume: 1, Issue:5

    Topics: Aging; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cell Count; Chromatography; Dactinomycin; Glutamine; Leucine; Models, Biological; Ornithine; Phenylalanine; Plant Proteins; Plants; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Threonine; Time Factors; Tyrosine

1973
A study of golden hamster (Cricetus cricetus) alkaline phosphatase isoenzymes.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1973, Sep-15, Volume: 46, Issue:1

    Topics: Aging; Alkaline Phosphatase; Aminocaproates; Animals; Bone and Bones; Cricetinae; Drug Stability; Fluorescence; Guanidines; Hot Temperature; Humans; Intestines; Isoenzymes; Liver; Phenylalanine; Species Specificity

1973
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
    Journal of neurochemistry, 1973, Volume: 21, Issue:5

    Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine

1973
Protein synthesis and loss of viability in rye embryos. The lability of transferase enzymes during senscence.
    The Biochemical journal, 1973, Volume: 135, Issue:3

    Topics: Acyltransferases; Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Carbon Radioisotopes; Cell-Free System; Edible Grain; Ethylmaleimide; Guanosine Triphosphate; Kinetics; Peptide Chain Elongation, Translational; Phenylalanine; Plant Proteins; Potassium; Ribosomes; RNA, Transfer; Seeds

1973
Lipid metabolism in liver and brain in acute hyperphenylalaninemia in rats of different ages. Correlation with tissue phenylalanine and tyrosine levels.
    Biology of the neonate, 1974, Volume: 24, Issue:3

    Topics: Acetates; Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Cholesterol; Chromatography, Thin Layer; Female; Glycolipids; Lipid Metabolism; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phospholipids; Rats; Time Factors; Tyrosine

1974
Arterial mesenchyme and arteriosclerosis. Enzymic vs non-enzymic factors in the deterioration of connective tissue.
    Advances in experimental medicine and biology, 1974, Volume: 43, Issue:0

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Blood Platelets; Cattle; Child; Collagen; Connective Tissue; Culture Techniques; Elastic Tissue; Elastin; Female; Fluorescence; Humans; Leukocytes; Male; Middle Aged; Pancreatic Elastase; Phenylalanine; Pregnancy; Proteins; Solubility; Tyrosine; Ultraviolet Rays; X-Ray Diffraction

1974
Effect of prolonged phenylalanine loading on the free amino-acid and lipid content of the infant monkey brain.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:6

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Blood-Brain Barrier; Brain Chemistry; Cerebrosides; Haplorhini; Lipids; Male; Organ Size; Phenylalanine

1966
[Biochemical studies on the age-related variations of the human intervertebral disc].
    Nihon Seikeigeka Gakkai zasshi, 1972, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography; Collagen; Galactosamine; Glucosamine; Hexosamines; Humans; Infant; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Phenylalanine; Potassium; Sodium; Thoracic Vertebrae; Tryptophan; Tyrosine

1972
A possible age-related modification of phenylalanine transfer RNA from wheat tissue.
    Experimental gerontology, 1972, Volume: 7, Issue:4

    Topics: Aging; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Phenylalanine; RNA, Transfer; Spectrometry, Fluorescence; Triticum

1972
Adequate phenylalanine intake for optimum growth and development in the treatment of phenylketonuria.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:4

    Topics: Age Factors; Aging; Body Height; Body Weight; Cephalometry; Child; Child Development; Child, Preschool; Diet Therapy; Dietary Proteins; Humans; Infant; Intelligence Tests; Nutritional Requirements; Phenylalanine; Phenylketonurias

1971
Serum alkaline phosphatase activity in cattle.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 33, Issue:2

    Topics: Abomasum; Aging; Alkaline Phosphatase; Animals; Bone and Bones; Brain; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Deficiency Diseases; Diarrhea; Duodenum; Female; Hydrogen-Ion Concentration; Isoenzymes; Kidney; Kinetics; Liver; Lung; Mammary Glands, Animal; Nitrophenols; Phenolphthaleins; Phenols; Phenylalanine; Phosphoric Acids; Placenta; Rumen; Spleen; Urea

1971
Preparation of two antigens of human liver isoenzymes of alkaline phosphatase.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 34, Issue:3

    Topics: Aging; Alkaline Phosphatase; Antibody Formation; Antigens; Arginine; Chromatography, Gel; Depression, Chemical; Humans; Immune Sera; Immunoelectrophoresis; Isoenzymes; Liver; Magnesium; Phenylalanine; Stimulation, Chemical

1971
Solubilization of a reticulocyte ribosomal fraction responsible for the decline in ribosomal activity with cell maturation.
    Archives of biochemistry and biophysics, 1971, Volume: 145, Issue:1

    Topics: Aging; Animals; Blood Proteins; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Chlorides; Deuterium; Electrophoresis; Hemoglobins; Leucine; Magnesium; Phenylalanine; Polynucleotides; Potassium Chloride; Reticulocytes; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Viral; Serum Albumin, Bovine; Solubility; Spectrophotometry; Time Factors; Tritium; Ultraviolet Rays; Uracil Nucleotides

1971
Alteration in microsomal protein synthesis during early development of mouse brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 62, Issue:3

    Topics: Aging; Animals; Brain; Centrifugation, Density Gradient; Ligases; Mice; Microsomes; Phenylalanine; Protein Biosynthesis; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Transfer; Tritium

1969
Inhibition of human brain pyruvate kinase and hexokinase by phenylalanine and phenylpyruvate: possible relevance to phenylketonuric brain damage.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 63, Issue:4

    Topics: Aging; Animals; Brain; Fetus; Gestational Age; Hexokinase; Humans; In Vitro Techniques; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pyruvate Kinase; Rats

1969
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine

1966
Absence of a life-shortening effect of amino-acid analogues on adult Drosophila.
    Experimental gerontology, 1969, Sep-03, Volume: 4, Issue:3

    Topics: Aging; Amino Acids; Animals; Antimetabolites; Dietary Proteins; Drosophila; Hydrocarbons, Halogenated; Leucine; Longevity; Male; Phenylalanine; Protein Biosynthesis; Tritium

1969
In vitro protein synthesis and aging in Rhizoctania solani.
    Journal of bacteriology, 1970, Volume: 101, Issue:3

    Topics: Aging; Amino Acids; Carbon Isotopes; Cell-Free System; Fungi; Ligases; Peptide Biosynthesis; Phenylalanine; Ribosomes

1970
Hyperphenylalaninemia: disaggregation of brain polyribosomes in young rats.
    Science (New York, N.Y.), 1970, Apr-03, Volume: 168, Issue:3927

    Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Cell-Free System; Centrifugation, Density Gradient; Disease Models, Animal; Humans; Injections, Intraperitoneal; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Rats; Ribosomes

1970
Dietary amino acid and nucleic acid imbalance leading to altered tumour frequency in the adult housefly, Musca domestica.
    Journal of insect physiology, 1968, Volume: 14, Issue:2

    Topics: Aging; Amino Acids; Animals; Dietary Proteins; Houseflies; Neoplasms; Nucleic Acids; Phenylalanine

1968
Effect of the administration of xanthine on the appearance of xanthine oxidase activity in the liver of growing rats.
    Experientia, 1968, Sep-15, Volume: 24, Issue:9

    Topics: Aging; Animals; Carbon Isotopes; Cortisone; Cycloheximide; Dactinomycin; Leucine; Liver; Orotic Acid; Phenylalanine; Rats; RNA; Xanthine Oxidase; Xanthines

1968
[Study of phenylalanine incorporation into proteins in a cell free system from chicken liver as a function of age].
    Biochimica et biophysica acta, 1968, Nov-20, Volume: 169, Issue:1

    Topics: Adenosine Triphosphate; Aging; Animals; Bile Acids and Salts; Carbon Isotopes; Cell-Free System; Chick Embryo; Chickens; In Vitro Techniques; Liver; Microsomes; Phenylalanine; Polynucleotides; Protein Biosynthesis; Ribosomes; RNA, Messenger; Uracil Nucleotides

1968
Errors in protein synthesis and clonal senescence in fungi.
    Nature, 1969, Mar-29, Volume: 221, Issue:5187

    Topics: Adenine; Aging; Ascomycota; Culture Media; Fluorouracil; Genetic Code; Genetics, Microbial; Mutation; Neurospora; Phenotype; Phenylalanine; Protein Biosynthesis; RNA; Suppression, Genetic

1969
Characterization of placental isoenzyme of alkaline phosphatase in human pregnancy serum.
    Canadian journal of biochemistry, 1969, Volume: 47, Issue:2

    Topics: Aging; Alkaline Phosphatase; Blood Protein Electrophoresis; Delivery, Obstetric; Female; Hot Temperature; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Isoenzymes; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Umbilical Cord; Vibrio

1969
Polyribosome concentration of mouse skeletal muscle as a function of age.
    Archives of biochemistry and biophysics, 1969, Volume: 130, Issue:1

    Topics: Aging; Animals; Brain; Centrifugation, Density Gradient; Enzymes; Hydrogen-Ion Concentration; Liver; Mice; Microsomes; Muscles; Phenylalanine; Polynucleotides; Potassium Chloride; Protein Biosynthesis; Ribonucleases; Ribosomes; RNA; Uracil Nucleotides

1969
Hyperphenylalaninemia: effect on the developing rat brain.
    Canadian journal of biochemistry, 1969, Volume: 47, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Humans; Injections, Subcutaneous; Lipid Metabolism; Liver; Mixed Function Oxygenases; Myelin Sheath; Organ Size; Phenylalanine; Phenylketonurias; Rats; Tyrosine

1969
The effect of age on protein synthesis in mouse liver.
    The Biochemical journal, 1969, Volume: 113, Issue:5

    Topics: Aging; Animals; Carbon Isotopes; Cell Nucleus; Chromatography, Gel; In Vitro Techniques; Liver; Mice; Microsomes; Phenylalanine; Polynucleotides; Protein Biosynthesis; RNA, Messenger; Surface-Active Agents; Ultracentrifugation

1969
Protein synthesis in growing-rat tissues. II. Polyribosome concentration of brain and liver as a function of age.
    Biochimica et biophysica acta, 1966, Jun-22, Volume: 119, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; In Vitro Techniques; Liver; Phenylalanine; Polynucleotides; Protein Biosynthesis; Rats; Ribosomes; Uracil Nucleotides

1966
Biochemistry of the developing rat brain. 8. Changes in the ribosomal system and nuclear RNA's.
    Biochimica et biophysica acta, 1966, Dec-21, Volume: 129, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell Nucleus; Hydrogen-Ion Concentration; Lysine; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA; RNA, Messenger; Ultracentrifugation; Ultraviolet Rays

1966
Brain amines and brain weights in growing chicks: some normal values and effects of feeding excess dietary l-phenylalanine.
    Biochemical pharmacology, 1966, Volume: 15, Issue:10

    Topics: Aging; Animals; Body Weight; Brain; Brain Chemistry; Diet; Female; Male; Norepinephrine; Organ Size; Phenylalanine; Poultry; Serotonin

1966