phenylalanine has been researched along with Aging in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 97 (55.43) | 18.7374 |
| 1990's | 24 (13.71) | 18.2507 |
| 2000's | 31 (17.71) | 29.6817 |
| 2010's | 17 (9.71) | 24.3611 |
| 2020's | 6 (3.43) | 2.80 |
| Authors | Studies |
|---|---|
| Buck, LB; Petrascheck, M; Ye, X | 1 |
| Ford, S; Hofman, DL; MacDonald, A; Vardy, ERLC | 1 |
| Burd, NA; Churchward-Venne, TA; de Groot, LCPGM; Dirks, ML; Fuchs, CJ; Gorissen, SHM; Groen, BBL; Holwerda, AM; Horstman, AMH; Koopman, R; Kouw, IWK; Pennings, B; Res, PT; Senden, JMG; Steijns, JMJM; Trommelen, J; van Loon, LJC; Verdijk, LB; Wall, BT | 1 |
| Bai, P; Chen, F; Chen, J; Li, M; Mao, D; Wang, R; Yang, L; Yang, X; Zhang, Y; Zhao, W | 1 |
| Church, DD; Ferrando, AA; Gwin, JA; Hirsch, KR; Kim, IY; Park, S; Pasiakos, SM; Wolfe, RR | 1 |
| Ball, RO; Chang, J; Courtney-Martin, G; Elango, R; Kong, D; Lebarron, M; Pencharz, PB; Rafii, M; Szwiega, S; Xu, L | 1 |
| Abatan, A; Adnot, S; Breau, M; Bréhat, J; Czibik, G; d'Humières, T; Delmont, T; Derumeaux, G; Halfaoui, M; Hatem, S; Liang, H; Marion, O; Martel, C; Mezdari, Z; Morin, D; Murat Altintas, D; Naushad, S; Pini, M; Radu, C; Sarwar, R; Sawaki, D; Suffee, N; Yavari, A; Zhang, Y | 1 |
| Barta, AG; Reismann, P; Sumánszki, C | 1 |
| Bůžková, P; Carbone, LD; Coughlin, SS; Fink, HA; Isales, CM; Le, B; Raiford, M; Robbins, JA; Shikany, JM | 1 |
| Ball, RO; Courtney-Martin, G; Elango, R; Martin, KE; Pencharz, PB; Rafii, M; Szwiega, S | 1 |
| Boirie, Y; Moreau, K; Walrand, S | 1 |
| Ball, RO; Campbell, WW; Elango, R; McCabe, GP; Pencharz, PB; Tang, M | 1 |
| Burd, NA; Gijsen, AP; Gorissen, SH; Groen, BB; Hamer, HM; van Loon, LJ | 1 |
| Berillo, L; Caputi, C; Carducci, C; Chiarotti, F; Di Biasi, C; Leuzzi, V; Manti, F; Mastrangelo, M; Nardecchia, F | 1 |
| Agergaard, J; Bülow, J; Holm, L; Kjaer, M; Reitelseder, S | 1 |
| Biolo, G; Di Girolamo, FG; Gasparini, M; Grassi, B; Lazzer, S; Mazzucco, S; Narici, M; Passaro, A; Pišot, R; Reggiani, C; Rittweger, J; Šimunič, B; Situlin, R | 1 |
| Eriksson, JG; Guzzardi, MA; Iozzo, P; Kajantie, E; Kautiainen, H; Salonen, MK | 1 |
| Aarsland, A; Chinkes, DL; Katsanos, CS; Paddon-Jones, D; Wolfe, RR; Zhang, XJ | 1 |
| Paddon-Jones, D; Sheffield-Moore, M; Symons, TB; Wolfe, RR | 1 |
| Chan, L; Guan, X; Guo, Y; Li, X; Wang, Y | 1 |
| Almeida, MF; Azevedo, I; Borges, N; Cardoso, ML; Carmona, C; Lima, MR; Rocha, JC; Salcedo, G; Soares, I; van Spronsen, FJ | 1 |
| Dickinson, JM; Drummond, MJ; Fry, CS; Glynn, EL; Gundermann, DM; Rasmussen, BB; Timmerman, KL; Volpi, E; Walker, DK | 1 |
| Mamerow, MM; Paddon-Jones, D; Sheffield-Moore, M; Symons, TB; Wolfe, RR | 1 |
| Ahmad, M; Casperson, SL; Dillon, EL; Durham, WJ; Kinsky, MP; Randolph, KM; Sheffield-Moore, M; Urban, RJ; Volpi, E | 1 |
| Bian, YH; Chu, W; Du, SJ; Li, H; Rotllant, P; Schneider, M; Shen, T; Xu, J; Zhang, J | 1 |
| de Lange, A; Gijsen, AP; Groen, B; Pennings, B; Senden, JM; van Loon, LJ; Zorenc, AH | 1 |
| Debrabander, A; Dobbelaere, D; Farriaux, JP; Gottrand, F; Michaud, L; Turck, D; Vanderbecken, S | 1 |
| Kobayashi, H; Mittendorfer, B; Sheffield-Moore, M; Volpi, E; Wolfe, RR | 1 |
| WALIGORA, Z; WENDER, M | 1 |
| ALLEN, RJ; HEFFELFINGER, JC; MASOTTI, RE; TSAU, MU | 1 |
| O'BRIEN, D | 1 |
| Bigelow, ML; Nair, KS; Proctor, DN; Short, KR; Vittone, JL | 1 |
| Aarsland, A; Ferrando, AA; Paddon-Jones, D; Sheffield-Moore, M; Volpi, E; Wolf, SE; Wolfe, RR; Zhang, XJ | 1 |
| Boulat, O; Boulos, M; Guignard, JP; Matthieu, JM; Van Melle, G | 1 |
| Bongiovanni, A; Bostrom, J; Campos, Y; Conaway, JW; D'Azzo, A; Hahn, C; Harris, AJ; Mann, L; Nastasi, T; Rottier, R; Toy, JN | 1 |
| Boirie, Y; Dardevet, D; Guillet, C; Mishellany, A; Rousset, P; Sornet, C; Zangarelli, A | 1 |
| Chinkes, DL; Morio, B; Paddon-Jones, D; Sheffield-Moore, M; Volpi, E; Wolf, SE; Wolfe, RR; Yeckel, CW | 1 |
| Hanley, WB | 1 |
| Johnson, DE; Sellinger, OZ | 1 |
| Aarsland, A; Katsanos, CS; Kobayashi, H; Sheffield-Moore, M; Wolfe, RR | 1 |
| Katsanos, CS; Paddon-Jones, D; Sheffield-Moore, M; Wolfe, RR; Zhang, XJ | 1 |
| Buchsbaum, MS; Sansaricq, C; Snyderman, SE; Wasserstein, MP | 1 |
| Akfur, C; Ekström, F; Lundberg, S; Tunemalm, AK | 1 |
| Fujita, S; Mittendorfer, B; Rasmussen, BB; Rowe, VL; Roy, M; Volpi, E; Wolfe, RR | 1 |
| Gijsen, AP; Gorselink, M; Koopman, R; Manders, RJ; Pijpers, E; van Loon, LJ; Verdijk, L; Wagenmakers, AJ | 1 |
| Butkevich, IP; Makukhina, GV; Mikhaĭlenko, VA | 1 |
| Chinkes, DL; Cocke, TL; Paddon-Jones, D; Schutzler, SE; Symons, TB; Wolfe, RR | 1 |
| Austic, RE; Lartey, FM | 1 |
| Lala, R; Mussa, A; Porta, F; Spada, M | 1 |
| Dhanani, S; Dillon, EL; Dreyer, HC; Drummond, MJ; Fry, CS; Pennings, B; Rasmussen, BB; Sheffield-Moore, M; Volpi, E | 1 |
| Carver, MJ; Copenhaver, JH; Schain, RJ; Underdahl, NR | 1 |
| Greengard, O; Isaacs, CE | 1 |
| Goldspink, DF; Kelly, FJ; Lewis, SE | 3 |
| Gregg, VA; Milligan, LP | 1 |
| Arakawa, T; Chikaoka, H; Katsushima, N; Kobayashi, M; Minagawa, A; Saito, TG; Shioji, R | 1 |
| Schneider, AJ | 1 |
| Anika, SM | 1 |
| Grüttner, R; Held, KR; Koepp, P; Plettner, C | 1 |
| Cramer, F; Deerberg, F; Engelhardt, R; Gabius, HJ | 1 |
| Bates, PC; Crie, JS; Griffin, EE; Millward, DJ; Wildenthal, K | 1 |
| Hardwick, J; Hsieh, WH; Liu, DS; Richardson, A | 1 |
| Butzow, JJ; Eichhorn, GL; McCool, MG | 1 |
| Ardouin, P; Dhondt, JL; Farriaux, JP; Hayte, JM | 1 |
| Druse, MJ; Figlewicz, DA | 1 |
| Ekstrom, R; Liu, DS; Richardson, A | 1 |
| Goto, S; Mizuno, D; Mori, N | 1 |
| Cooke, AR; Cooke, HJ; Pfankuche, L | 1 |
| Brummel, MC; Lindgren, SD; Stegink, LD; Stumbo, PJ; Wolraich, ML | 1 |
| Bloomfield, PM; Fukuda, H; Hatazawa, J; Iida, H; Ito, H; Kanno, I; Miura, S; Murakami, M; Uemura, K | 1 |
| Greve, J; Otto, K; Puppels, GJ; Smeets, MH; Vrensen, GF | 1 |
| Kee, AJ; Smith, RC | 1 |
| Abrams, SM; Heybroek, WM; Jackson, SH; Johnston, A; Maskrey, V; Puthrasingam, S; Swift, CG; Turner, P | 1 |
| Chagneau, AM; Maaa, N; Peresson, R; Tesseraud, S | 1 |
| Ahlrichs, JA; Denne, SC; Karn, CA; Leitch, CA; Liechty, EA; Poindexter, BB; Wang, J | 1 |
| Arnold, LA; Bebin, EM; Fryburg, JS; Gunasekera, RS; Hyland, K; Jacobson, RD; Rost-Ruffner, E; Trugman, JM; Wilson, WG | 1 |
| Fu, A; Nair, KS | 1 |
| Denecke, J; Feldmann, R; Grenzebach, M; Pietsch, M; Sprinz, A; Ullrich, K; Weglage, J | 1 |
| Mittendorfer, B; Volpi, E; Wolf, SE; Wolfe, RR | 1 |
| Angelogianni, P; Schulpis, KH; Stavridis, JC; Tsakiris, S | 1 |
| Arner, EC; Pratta, MA; Tortorella, MD | 1 |
| Burgard, P; Schweitzer-Krantz, S | 1 |
| Cipcic-Schmidt, S; Koch, R; Trefz, FK | 1 |
| Brown, G; Castro, E; Deeb, SS; Edland, SD; Erkkola, R; Lee, L; Louhija, J; Martin, GM; Ogburn, CE; Oshima, J; Panduro, A; Penttinen, R; Riestra, R; Tilvis, R; Wang, L | 1 |
| Tsakiris, S | 1 |
| Rasmussen, BB; Sheffield-Moore, M; Volpi, E; Wolfe, RR | 1 |
| Corvol, P; Kempf, H; Nishimura, H; Wideman, RF; Xi, Z; Zhang, L | 1 |
| Daniels, VG; Murphy, S | 1 |
| Del Valle, JA; Greengard, O | 1 |
| Days, R; Harris, W; Hubert, C; Johnson, C; Stallworth, J | 1 |
| Greengard, O; Sanchez-Urretia, L | 1 |
| Wheatley, DN | 1 |
| Dell'orco, RT; Duncan, MR | 1 |
| Berry, HK; Butcher, RE; Kazmaier-Novak, KJ; Kindt, CW; Vorhees, CV | 1 |
| Gilbert, BE | 1 |
| Holliday, R; Stevens, A | 1 |
| Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
| Bozcuk, AN | 1 |
| Mariotti, D; Ruscitto, R | 1 |
| DeLong, R; Poplin, L | 1 |
| Bielka, H; Henske, A; Schneiders, I; Venker, L | 1 |
| Davison, AN; Johnson, D; Lim, L; White, J | 1 |
| Kurtz, DI | 1 |
| Johnson, TC; Taub, F | 1 |
| Morelos, BS; Roberts, S | 1 |
| Comolli, R; Delpiano, C; Schubert, AC | 1 |
| Jefferson, LS; Kimball, SR; Vary, TC | 1 |
| Ingram, RL; Lenham, JE; Sonntag, WE | 1 |
| Hommes, FA; Moss, L | 1 |
| Camacho, JA; Morgan, HE; Peterson, CJ; White, GJ | 1 |
| Baillie, AG; Garlick, PJ | 1 |
| Abbasi, AA; Chaudry, F; Mattson, DE; Rudman, D | 1 |
| Burrin, DG; Davis, TA; Fiorotto, ML; Reeds, PJ | 1 |
| Batzler, U; Schmidt, H; Ullrich, K; Wendel, U | 1 |
| Batzler, U; Bickel, H; König, T; Michel, U; Schmidt, E; Schmidt, H; Trefz, FK | 1 |
| Batzler, U; Benninger, C; Heusser, A; Lütcke, A; Pietz, B; Pietz, J; Sontheimer, D | 1 |
| Bennett, LE; Keku, EO; Lecce, JG; Quinn, J; Rhoads, JM | 1 |
| Favilli, F; Iantomasi, T; Stio, M; Treves, C; Vincenzini, MT | 1 |
| Geesin, JC; Gordon, JS; Gracy, RW; Jacobson, TM; Lane, AT; Yüksel, KU | 1 |
| Goldspink, DF | 1 |
| Austin, BP; Menahan, LA; Sobocinski, KA | 1 |
| Hommes, F; Matsuo, K; Moss, L | 1 |
| Wilson, RP | 1 |
| Latulippe, J; Laughrea, M | 1 |
| Goto, S; Takahashi, R | 1 |
| Hommes, FA; Matsuo, K | 1 |
| Barron, BC; Kuck, JF; Yu, NT | 1 |
| Navab, F; Winter, CG | 1 |
| Hylka, VW; Meites, J; Sonntag, WE | 1 |
| Carver, MJ; Copenhaver, JH; Johnson, EA; Saxton, MJ | 1 |
| Nordyke, EL; Roach, MK | 1 |
| Jakubiec-Puka, A; Mochnacka, I | 1 |
| Johnson, RC; Shah, SN | 1 |
| Rauch, H; Siegel, SJ | 1 |
| Dunlop, DS; Lajtha, A; Van Elden, W | 1 |
| Cristofalo, VJ; Duda, G; Ryan, JM | 1 |
| Gilbert, BE; Johnson, TC | 2 |
| Markiewicz, L; Weinstock, IM | 1 |
| Boross, M; Pénzes, L | 1 |
| Schlesinger, K; Uphouse, LL | 1 |
| Pénzes, L | 2 |
| Chaudhary, KD; Richard, C | 1 |
| Bemiller, JN; Hoffmann, WE; Pappelis, AJ | 1 |
| Cox, RA; Gökcen, M | 1 |
| Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
| Osborne, DJ; Roberts, BE | 1 |
| Geison, RL; Josephson, L | 1 |
| LaBella, FS | 1 |
| Ibbot, FA; O'Brien, D | 1 |
| Murayama, K | 1 |
| Shugart, L | 1 |
| Smith, BA; Waisman, HA | 1 |
| Healy, PJ | 1 |
| Fishman, L; Fishman, WH; Inglis, NR | 1 |
| Adams, MH; Midthun, RA; Rowley, PT | 1 |
| Belytschko, G; Johnson, TC | 1 |
| Weber, G | 1 |
| Graeber, W | 1 |
| Dingley, F; Smith, JM | 1 |
| Gottlieb, D; Obrig, TG | 1 |
| Aoki, K; Siegel, FL | 1 |
| Bodnaryk, RP | 1 |
| Spadoni, MA; Ticca, M | 1 |
| Beck, G; Clavert, J; Ebel, JP; Kallmeyer, MA; Prevost, C | 1 |
| Holliday, R | 1 |
| Fishman, WH; Ghosh, NK | 1 |
| Srivastava, U | 1 |
| Clarke, JT; Lowden, JA | 1 |
| Mainwaring, WI | 1 |
| Murthy, MR | 1 |
| Fritz, RR; Rappoport, DA; Yamagami, S | 1 |
| Pscheidt, GR; Tamimie, HS | 1 |
7 review(s) available for phenylalanine and Aging
| Article | Year |
|---|---|
Phenylketonuria, co-morbidity, and ageing: A review.
Topics: Adult; Aged; Aging; Comorbidity; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias | 2020 |
Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans.
Topics: Adult; Aged; Aging; Biological Transport; Dietary Proteins; Digestion; Female; Humans; Hyperglycemia; Male; Middle Aged; Phenylalanine | 2020 |
[Adult phenylketonuria].
Topics: Adult; Age Factors; Aging; Female; Health Services Accessibility; Humans; Long-Term Care; Male; Middle Aged; Phenylalanine; Phenylketonurias | 2017 |
Adult phenylketonuria.
Topics: Adult; Aging; Female; Humans; Infant, Newborn; Intelligence; Phenylalanine; Phenylketonurias | 2004 |
Biological and biochemical effects of phenylalanine analogs.
Topics: Aging; Animals; Cell Division; Enzyme Induction; Enzyme Repression; Flagella; Mutation; Neoplasms; Phenylalanine; Protein Biosynthesis; RNA; Transfer RNA Aminoacylation; Viruses | 1978 |
Protein and amino acid requirements of fishes.
Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine | 1986 |
Pyridoxine dependency and central nervous system excitability.
Topics: Acoustic Stimulation; Aging; Aminobutyrates; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Genotype; Mice; Mice, Inbred Strains; Norepinephrine; Pentylenetetrazole; Phenylalanine; Phenylalanine Hydroxylase; Physostigmine; Pyridoxine; Reserpine; Seizures; Serotonin; Tetrabenazine; Thiosemicarbazones | 1972 |
14 trial(s) available for phenylalanine and Aging
| Article | Year |
|---|---|
Assessment of protein requirement in octogenarian women with use of the indicator amino acid oxidation technique.
Topics: Aged, 80 and over; Aging; Body Mass Index; Breath Tests; Carbon Isotopes; Dietary Proteins; Feasibility Studies; Female; Humans; Indiana; Kinetics; National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division; Nutrition Assessment; Nutritional Requirements; Overweight; Oxidation-Reduction; Phenylalanine; Recommended Dietary Allowances; United States; White People | 2014 |
Carbohydrate coingestion delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion.
Topics: Aged; Aging; Blood Glucose; Dietary Carbohydrates; Dietary Proteins; Digestion; Eating; Humans; Intestinal Absorption; Male; Muscle Proteins; Phenylalanine; Postprandial Period; Young Adult | 2014 |
No additional effect of different types of physical activity on 10-hour muscle protein synthesis in elderly men on a controlled energy- and protein-sufficient diet.
Topics: Activities of Daily Living; Aged; Aging; Bed Rest; Diet; Dietary Proteins; Exercise; Humans; Insulin; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Resistance Training | 2016 |
Whey protein ingestion in elderly persons results in greater muscle protein accrual than ingestion of its constituent essential amino acid content.
Topics: Aged; Aged, 80 and over; Aging; Amino Acids, Essential; Dietary Supplements; Digestion; Female; Humans; Male; Middle Aged; Milk Proteins; Muscle Proteins; Nutritional Requirements; Phenylalanine; Whey Proteins | 2008 |
A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects.
Topics: Adult; Aged; Aging; Analysis of Variance; Biopsy; Carbon Isotopes; Dietary Proteins; Dose-Response Relationship, Drug; Female; Humans; Male; Meat; Muscle Proteins; Muscle, Skeletal; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine | 2009 |
The anabolic response to resistance exercise and a protein-rich meal is not diminished by age.
Topics: Adult; Aged; Aging; Biopsy; Dietary Proteins; Exercise; Female; Humans; Male; Meat; Muscle Proteins; Phenylalanine; Quadriceps Muscle; Resistance Training | 2011 |
Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men.
Topics: Aged; Aging; Algorithms; Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Digestion; Humans; Insulin; Intestinal Absorption; Kinetics; Male; Milk Proteins; Muscle Proteins; Oxidation-Reduction; Phenylalanine; Postprandial Period; Quadriceps Muscle; Tyrosine; Whey Proteins | 2012 |
Evaluation of nutritional status and pathophysiology of growth retardation in patients with phenylketonuria.
Topics: Aging; Anthropometry; Body Composition; Body Height; Body Weight; Child; Child, Preschool; Chromatography, Gas; Cross-Sectional Studies; Diet; Erythrocytes; Female; Growth Disorders; Hormones; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Nutritional Status; Phenylalanine; Phenylketonurias; Thyroid Hormones; Trace Elements; Tyrosine | 2003 |
Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults.
Topics: Aged; Aging; Amino Acids, Essential; Dietary Supplements; Humans; Insulin; Muscle Proteins; Muscles; Phenylalanine | 2003 |
Age and aerobic exercise training effects on whole body and muscle protein metabolism.
Topics: Adult; Aged; Aging; Body Composition; Energy Metabolism; Exercise; Female; Follow-Up Studies; Humans; Leucine; Male; Middle Aged; Muscle Proteins; Phenylalanine; Proteins; Radioactive Tracers; Reference Values | 2004 |
Amino acid ingestion improves muscle protein synthesis in the young and elderly.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aging; Amino Acids, Essential; Female; Humans; Inulin; Male; Muscle Proteins; Phenylalanine | 2004 |
Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men.
Topics: Activities of Daily Living; Adult; Aged; Aging; Carbon Isotopes; Cross-Over Studies; Dietary Carbohydrates; Dietary Proteins; Double-Blind Method; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Tyrosine | 2006 |
Phenylalanine requirement, imbalance, and dietary excess in one-week-old chicks: growth and phenylalanine hydroxylase activity.
Topics: Aging; Animals; Chickens; Dose-Response Relationship, Drug; Male; Nutritional Requirements; Phenylalanine; Phenylalanine Hydroxylase; Weight Gain | 2008 |
Erythrocyte L-aspartyl-L-phenylalanine hydrolase activity and plasma phenylalanine and aspartate concentrations in children consuming diets high in aspartame.
Topics: Aging; Analysis of Variance; Aspartame; Aspartic Acid; Child; Child Behavior; Child, Preschool; Cognition; Diet; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Humans; Hydrolases; Phenylalanine; Sweetening Agents | 1995 |
154 other study(ies) available for phenylalanine and Aging
| Article | Year |
|---|---|
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation | 2007 |
Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
Topics: Aged; Aging; Amino Acids; Body Weight; China; Dietary Proteins; Energy Intake; Energy Metabolism; Female; Humans; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Recommended Dietary Allowances; Tyrosine | 2020 |
Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding.
Topics: Aging; Amino Acids; Amino Acids, Essential; Dietary Supplements; Eating; Food; Humans; Kinetics; Male; Metabolism; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Postprandial Period; Protein Biosynthesis; Whey Proteins | 2020 |
Dietary leucine requirement of older men and women is higher than current recommendations.
Topics: Aged; Aging; Dose-Response Relationship, Drug; Female; Humans; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine | 2021 |
Dysregulated Phenylalanine Catabolism Plays a Key Role in the Trajectory of Cardiac Aging.
Topics: Aging; Amino Acids; Animals; Biomarkers; Biopterins; Catalysis; Cellular Senescence; Disease Models, Animal; Disease Susceptibility; Heart Diseases; Humans; Liver; Male; Mice; Mice, Knockout; Models, Biological; Myocardium; Myocytes, Cardiac; Phenylalanine; Rats | 2021 |
The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Amino Acids, Aromatic; Body Composition; Body Mass Index; Bone Density; Diet; Diet Surveys; Ethnicity; Female; Hip Fractures; Humans; Male; Multivariate Analysis; Osteoporosis; Phenylalanine; Risk; Tryptophan; Tyrosine | 2019 |
The Phenylalanine Requirement of Elderly Men and Women Measured by Direct 13C Carbon Oxidation Method Is Similar to That of Young Adults.
Topics: Aged; Aged, 80 and over; Aging; Carbon Isotopes; Female; Humans; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine | 2019 |
Protein redistribution from skeletal muscle to splanchnic tissue on fasting and refeeding in young and older healthy individuals.
Topics: Aged; Aging; Albumins; Body Composition; Carbon Isotopes; Eating; Fasting; Female; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Splanchnic Circulation; Young Adult | 2013 |
The outcome of white matter abnormalities in early treated phenylketonuric patients: A retrospective longitudinal long-term study.
Topics: Adolescent; Adult; Aging; Child; Female; Follow-Up Studies; Humans; Intelligence Tests; Longitudinal Studies; Magnetic Resonance Imaging; Male; Phenylalanine; Phenylketonurias; Retrospective Studies; White Matter; Young Adult | 2015 |
Anabolic resistance assessed by oral stable isotope ingestion following bed rest in young and older adult volunteers: Relationships with changes in muscle mass.
Topics: Aging; Bed Rest; Body Mass Index; Case-Control Studies; Humans; Isotopes; Magnetic Resonance Imaging; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Phenylalanine; Postprandial Period; Protein Biosynthesis; Young Adult | 2017 |
Higher serum phenylalanine concentration is associated with more rapid telomere shortening in men.
Topics: Aged; Aging; Amino Acids; Cohort Studies; Cross-Sectional Studies; Female; Finland; Humans; Leukocytes; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Real-Time Polymerase Chain Reaction; Risk Factors; Sex Factors; Telomere; Telomere Shortening | 2017 |
alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice.
Topics: Aging; Animals; Antioxidants; Blotting, Western; Body Composition; Calorimetry, Indirect; Cell Line; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Energy Metabolism; Fatty Acids; Glucose Tolerance Test; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Thioctic Acid; Trans-Activators; Transcription Factors | 2010 |
The use of prealbumin concentration as a biomarker of nutritional status in treated phenylketonuric patients.
Topics: Adolescent; Adult; Aging; Biomarkers; Child; Child, Preschool; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Intake; Female; Humans; Infant; Male; Nutritional Status; Phenylalanine; Phenylketonurias; Prealbumin; Young Adult | 2010 |
Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.
Topics: Activating Transcription Factor 4; Active Transport, Cell Nucleus; Adult; Age Factors; Aged; Aging; Amino Acid Transport Systems; Amino Acids; Analysis of Variance; Biopsy; Blotting, Western; Eukaryotic Initiation Factor-2; Female; Gene Expression Regulation; Humans; Leucine; Male; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Muscle Contraction; Phenylalanine; Phosphorylation; Polymerase Chain Reaction; Quadriceps Muscle; Resistance Training; Ribosomal Protein S6; RNA, Messenger; STAT3 Transcription Factor; Time Factors; TOR Serine-Threonine Kinases | 2011 |
Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia.
Topics: Adult; Age Factors; Aged; Aging; Amino Acids; Biopsy; Blood Flow Velocity; Blood Glucose; Female; Humans; Hyperemia; Infusions, Intra-Arterial; Infusions, Intravenous; Insulin; Lower Extremity; Male; Microcirculation; Microdialysis; Muscle Proteins; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Phenylalanine; Regional Blood Flow; Time Factors | 2011 |
Smyd1b_tv1, a key regulator of sarcomere assembly, is localized on the M-line of skeletal muscle fibers.
Topics: Aging; Alternative Splicing; Amino Acid Sequence; Animals; Cell Differentiation; Embryo, Nonmammalian; Gene Knockdown Techniques; Green Fluorescent Proteins; Histone-Lysine N-Methyltransferase; HSP90 Heat-Shock Proteins; Molecular Sequence Data; Muscle Development; Muscle Fibers, Skeletal; Mutagenesis, Insertional; Myofibrils; Phenylalanine; Protein Isoforms; Protein Transport; Recombinant Fusion Proteins; Sarcomeres; Serine; Subcellular Fractions; Time Factors; Zebrafish; Zebrafish Proteins | 2011 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
PHENYLALANINE HYDROXYLASE ACTIVITY IN NEWBORN INFANTS.
Topics: Aging; Black People; Blood Chemical Analysis; Carrier State; Clinical Laboratory Techniques; Diet; Genetics, Medical; Humans; Infant; Infant, Newborn; Laboratories; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Urine; White People | 1964 |
THE RELATION OF THE FREE PHENYLALANINE CONTENT OF MOUSE BRAIN TO AGE: ITS POSSIBLE SIGNIFICANCE IN PHENYLKETONURIA.
Topics: Aging; Amino Acids; Animals; Biochemical Phenomena; Brain; Brain Chemistry; Mice; Nitrogen; Phenylalanine; Phenylketonurias; Research | 1964 |
Correlation between plasma and urine phenylalanine concentrations.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Humans; Infant; Intellectual Disability; Phenylalanine; Phenylketonurias; Pilot Projects | 2004 |
Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.
Topics: Aging; Animals; beta Catenin; Blotting, Northern; Blotting, Western; Cells, Cultured; Cytoskeletal Proteins; Embryo, Mammalian; Epoxy Compounds; Gene Expression Regulation, Developmental; Heart; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Mice, Knockout; Microscopy, Electron; Muscle Development; Muscle, Skeletal; Mutation; Myoblasts; Myogenin; Phenylalanine; Precipitin Tests; Repressor Proteins; Sarcomeres; Staining and Labeling; Subcellular Fractions; Tenascin; Trans-Activators; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Ubiquitins | 2004 |
Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle.
Topics: Aging; Alanine; Animals; Diet; Leucine; Male; Mitochondrial Proteins; Muscle Proteins; Muscle, Skeletal; Myosin Heavy Chains; Phenylalanine; Rats; Rats, Wistar; Sarcoplasmic Reticulum | 2004 |
Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise.
Topics: Adult; Aged; Aging; Exercise; Fibrinogen; Humans; Male; Muscle Proteins; Osmolar Concentration; Phenylalanine; Regional Blood Flow; Serum Albumin | 2004 |
Age-dependent utilization of phenylalanine for the synthesis of neuronal and glial proteins.
Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Injections; Male; Nerve Tissue Proteins; Neuroglia; Neurons; Phenylalanine; Rats; Rats, Sprague-Dawley | 1973 |
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids.
Topics: Adult; Age Factors; Aged; Aging; Amino Acids, Essential; Area Under Curve; Deuterium; Female; Humans; Infusions, Intravenous; Leg; Male; Muscle Proteins; Phenylalanine; Postprandial Period; Regional Blood Flow | 2005 |
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein.
Topics: Administration, Oral; Aged; Aging; Amino Acids; Analysis of Variance; Female; Humans; Leg; Male; Milk Proteins; Muscle Proteins; Phenylalanine; Regional Blood Flow; Whey Proteins | 2006 |
Cerebral glucose metabolism in adults with early treated classic phenylketonuria.
Topics: Adult; Aging; Case-Control Studies; Cerebral Cortex; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Phenylalanine; Phenylketonurias; Pilot Projects; Positron-Emission Tomography; Time Factors | 2006 |
Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase.
Topics: Acetylcholinesterase; Aging; Animals; Binding Sites; Catalysis; Cholinesterase Inhibitors; Histidine; Humans; Mice; Molecular Conformation; Organophosphates; Organophosphorus Compounds; Phenylalanine; Water | 2006 |
Insulin resistance of muscle protein metabolism in aging.
Topics: Adult; Aged; Aging; Blood Flow Velocity; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Leg; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine | 2006 |
[Antinociceptive properties of the 5-HT3 receptor antagonist in the model of inflammatory pain in rats of different age with prenatal deficit of serotonine and under stress].
Topics: Aging; Analgesics; Animals; Female; Inflammation; Male; Ondansetron; Pain; Phenylalanine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Stress, Physiological | 2007 |
Aging does not impair the anabolic response to a protein-rich meal.
Topics: Adipose Tissue; Adult; Aged; Aging; Amino Acids; Amino Acids, Essential; Body Mass Index; Carbon Isotopes; Dietary Proteins; Female; Humans; Infusions, Intravenous; Male; Meat; Middle Aged; Phenylalanine | 2007 |
Phalangeal quantitative ultrasound in children with phenylketonuria: a pilot study.
Topics: Adult; Aging; Body Mass Index; Cross-Sectional Studies; Female; Finger Phalanges; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Pilot Projects; Ultrasonography | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blotting, Western; Extracellular Signal-Regulated MAP Kinases; Glucose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hormones; Humans; Hydrocortisone; Lactic Acid; Leucine; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Phosphorylation; Physical Fitness; Protein Kinases; RNA; Signal Transduction; TOR Serine-Threonine Kinases | 2008 |
Protein metabolism in the developing brain: influence of birth and gestational age.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Diseases; Carbon Isotopes; Nerve Tissue Proteins; Phenylalanine; Swine | 1967 |
The effect of hyperphenylalaninaemia on glycine metabolism in developing rat brain.
Topics: Aging; Amino Acids; Animals; Brain; Glycine; Neurotransmitter Agents; Phenylalanine; Rats; Serotonin | 1980 |
Pre- and post-natal growth and protein turnover in smooth muscle, heart and slow- and fast-twitch skeletal muscles of the rat.
Topics: Aging; Animals; DNA; Heart; Male; Muscle Development; Muscle Proteins; Muscle, Smooth; Muscles; Myocardium; Phenylalanine; Rats; Rats, Inbred Strains; RNA | 1984 |
Protein synthesis during the developmental growth of the small and large intestine of the rat.
Topics: Aging; Animals; DNA; Intestinal Mucosa; Intestine, Large; Intestine, Small; Male; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA | 1984 |
In vitro energy costs of Na+, K+ATPase activity and protein synthesis in muscle from calves differing in age and breed.
Topics: Aging; Animals; Cattle; Culture Techniques; Male; Muscle Proteins; Muscles; Oxygen Consumption; Phenylalanine; Sodium-Potassium-Exchanging ATPase; Species Specificity; Tyrosine | 1982 |
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine | 1982 |
Newborn phenylalanine/tyrosine metabolism. Implications for screening for phenylketonuria.
Topics: Aging; Fetal Blood; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1983 |
Ontogeny of cholecystokinin satiety in rats.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Cholecystokinin; Feeding Behavior; Female; Male; Phenylalanine; Rats; Stereoisomerism | 1983 |
Plasma amino acid pattern at noon in early treated hyperphenylalaninemic, phenylketonuric, and normal children.
Topics: Adolescent; Aging; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Female; Glutamine; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Time Factors | 1983 |
Age-related changes in different steps of protein synthesis of liver and kidney of rats.
Topics: Aging; Animals; Kidney; Kinetics; Liver; Male; Methionine; Organ Specificity; Phenylalanine; Protein Biosynthesis; Proteins; Puromycin; Rats; Rats, Inbred Strains | 1983 |
Age-related alterations in cardiac protein turnover.
Topics: Aging; Animals; Heart; In Vitro Techniques; Insulin; Kinetics; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Tyrosine | 1981 |
Cell-free protein synthesis by kidney from the aging female Fischer F344 rat.
Topics: Aging; Animals; Cell-Free System; Female; Kidney; Magnesium; Microsomes; Phenylalanine; Poly U; Potassium; Protein Biosynthesis; Rats; Rats, Inbred F344; Ribonucleases; Ribosomes; Valine | 1981 |
Does the capacity of ribosomes to control translation fidelity change with age?
Topics: Aging; Animals; Dose-Response Relationship, Drug; Leucine; Magnesium; Male; Paromomycin; Peptide Chain Elongation, Translational; Phenylalanine; Poly U; Rats; Ribosomes | 1981 |
Developmental aspects of pteridine metabolism and relationships with phenylalanine metabolism.
Topics: Adolescent; Adult; Aging; Amniotic Fluid; Animals; Biopterins; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neopterin; Phenylalanine; Phenylketonurias; Pregnancy; Pteridines; Rats; Rats, Inbred Strains | 1981 |
Experimental hyperphenylalaninemia: effect on central nervous system myelin subfractions.
Topics: Aging; Brain; Glucose; Glycine; Myelin Proteins; Myelin Sheath; Nerve Tissue Proteins; Phenylalanine | 1980 |
Changes in brain protein synthesis during the life span of male Fischer rats.
Topics: Aging; Animals; Brain; Cell-Free System; DNA; Leucine; Male; Nerve Tissue Proteins; Phenylalanine; Rats; Ribosomes; RNA | 1980 |
Translational activity and fidelity of purified ribosomes from aging mouse livers.
Topics: Aging; Animals; In Vitro Techniques; Leucine; Liver; Mice; Phenylalanine; Protein Biosynthesis; RNA, Ribosomal | 1980 |
Tryptophan transport by isolated newborn rabbit jejunum.
Topics: Aging; Alanine; Animals; Animals, Newborn; Intestinal Absorption; Jejunum; Phenylalanine; Rabbits; Sodium; Tryptophan | 1980 |
Aging effect on neutral amino acid transport at the blood-brain barrier measured with L-[2-18F]-fluorophenylalanine and PET.
Topics: Adult; Aged; Aging; Amino Acids; Biological Transport; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Phenylalanine; Tomography, Emission-Computed | 1995 |
Local variations in protein structure in the human eye lens: a Raman microspectroscopic study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Microchemistry; Middle Aged; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1993 |
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine | 1993 |
Aspartame pharmacokinetics - the effect of ageing.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartame; Female; Humans; Male; Metabolic Clearance Rate; Phenylalanine; Pilot Projects; Reference Values | 1996 |
Relative responses of protein turnover in three different skeletal muscles to dietary lysine deficiency in chicks.
Topics: Aging; Analysis of Variance; Animal Feed; Animals; Chickens; Diet; Lysine; Male; Muscle Development; Muscle, Skeletal; Organ Size; Organ Specificity; Phenylalanine; Protein Biosynthesis; Tritium | 1996 |
Amino acids suppress proteolysis independent of insulin throughout the neonatal period.
Topics: Aging; Amino Acids; Blood Glucose; Humans; Hydroxylation; Infant, Newborn; Infusions, Intravenous; Insulin; Leucine; Osmolar Concentration; Oxidation-Reduction; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Tyrosine | 1997 |
Oral phenylalanine loading in dopa-responsive dystonia: a possible diagnostic test.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biopterins; Child, Preschool; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female; Humans; Male; Middle Aged; Neopterin; Osmolar Concentration; Phenylalanine; Time Factors; Tyrosine | 1997 |
Age effect on fibrinogen and albumin synthesis in humans.
Topics: Adult; Aged; Aging; Female; Fibrinogen; Humans; Keto Acids; Leucine; Male; Middle Aged; Osmolar Concentration; Phenylalanine; Protein Precursors; Serum Albumin | 1998 |
Regression of neuropsychological deficits in early-treated phenylketonurics during adolescence.
Topics: Adolescent; Aging; Central Nervous System Diseases; Child; Female; Humans; Intelligence; Longitudinal Studies; Male; Mental Disorders; Motor Skills; Phenylalanine; Phenylketonurias | 1999 |
Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction.
Topics: Administration, Oral; Adult; Aged; Aging; Amino Acids; Female; Humans; Kinetics; Male; Models, Biological; Muscle Proteins; Phenylalanine; Splanchnic Circulation | 1999 |
Protective effect of L-phenylalanine on rat brain acetylcholinesterase inhibition induced by free radicals.
Topics: Acetylcholinesterase; Aging; Animals; Ascorbic Acid; Brain; Cholinesterase Inhibitors; Female; Ferric Compounds; Ferrous Compounds; Free Radicals; Frontal Lobe; Hippocampus; Hydrogen Peroxide; Hypothalamus; Kinetics; Male; Phenylalanine; Pituitary Gland; Rats; Rats, Wistar | 2000 |
Age-related changes in aggrecan glycosylation affect cleavage by aggrecanase.
Topics: Age Factors; Aggrecans; Aging; Alanine; Animals; beta-Galactosidase; Blotting, Western; Cattle; Chondroitin Sulfates; Chondroitinases and Chondroitin Lyases; Endopeptidases; Extracellular Matrix Proteins; Freezing; Glutamine; Glycosaminoglycans; Glycoside Hydrolases; Glycosylation; Keratan Sulfate; Lectins, C-Type; Matrix Metalloproteinase 3; Phenylalanine; Proteoglycans; Serine; Time Factors | 2000 |
Survey of national guidelines for the treatment of phenylketonuria.
Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Data Collection; Europe; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Practice Guidelines as Topic; Time Factors; United States | 2000 |
Final intelligence in late treated patients with phenylketonuria.
Topics: Adult; Aging; Humans; Intelligence; Phenylalanine; Phenylketonurias; Regression Analysis; Retrospective Studies; Stanford-Binet Test; Time Factors; Wechsler Scales | 2000 |
Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Substitution; Arginine; Arteriosclerosis; Coronary Artery Disease; Cysteine; Finland; Gene Frequency; Genotype; Haplotypes; Humans; Infant, Newborn; Leucine; Longevity; Mexico; Middle Aged; Phenylalanine; Polymorphism, Genetic; Werner Syndrome | 2000 |
Effects of L-phenylalanine on acetylcholinesterase and Na(+), K(+)-ATPase activities in adult and aged rat brain.
Topics: Acetylcholinesterase; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Eels; Female; Male; Phenoxybenzamine; Phenylalanine; Propranolol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2001 |
Basal muscle amino acid kinetics and protein synthesis in healthy young and older men.
Topics: Adult; Aged; Aging; Amino Acids; Basal Metabolism; Biopsy, Needle; Catheterization, Peripheral; Cross-Sectional Studies; Humans; Indocyanine Green; Kinetics; Magnetic Resonance Imaging; Male; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Proteins; Testosterone | 2001 |
Maturation-dependent neointima formation in fowl aorta.
Topics: Actins; Aging; Animals; Aorta, Abdominal; Arginine; Asparagine; Blood Pressure; Chickens; Cholesterol; Female; Hyperplasia; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nitric Oxide; Ornithine; Phenylalanine; Tunica Intima | 2001 |
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine | 1979 |
Isoenzyme composition of hepatic phenylalanine hydroxylase in developing rats after treatment with cortisol, alpha-methylphenylalanine and p-chlorophenylalanine in vivo.
Topics: Aging; Animals; Animals, Newborn; Fenclonine; Fetus; Hydrocortisone; Isoenzymes; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats | 1978 |
Studies on avian heart pyruvate kinase during development.
Topics: Adenosine Triphosphate; Aging; Alanine; Animals; Chickens; Diphosphates; Heart; Kinetics; Myocardium; Phenylalanine; Pyruvate Kinase | 1977 |
Phenylalanine-pyruvate aminotransferase in immature and adult mammalian tissues. Induction in fetal rat liver.
Topics: Adult; Aging; Animals; Brain; Carcinoma, Hepatocellular; Enzyme Induction; Female; Fetus; Gestational Age; Humans; Liver; Liver Neoplasms; Lung; Neoplasms, Experimental; Organ Specificity; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Pyruvates; Rats; Species Specificity; Structure-Activity Relationship; Transaminases | 1977 |
Effects of the incorporation of p-fluorophenylalanine on the in vitro lifespan of human diploid cells.
Topics: Aging; Cell Division; Cell Survival; Cells, Cultured; Diploidy; Fibroblasts; Glucosephosphate Dehydrogenase; Hot Temperature; Humans; p-Fluorophenylalanine; Phenylalanine; Time Factors | 1979 |
Induced PKU in rats: effects of age and melatonin treatment.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Humans; Learning; Melatonin; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Time Factors; Tyrosine | 1977 |
Ribosomal activity in prenatal mouse brain.
Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Animals, Newborn; Brain; Female; Mice; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Ribosomes | 1978 |
The effect of an amino acid analogue, p-fluorophenylalanine, on longevity of mice.
Topics: Aging; Animals; Body Weight; Diet; Female; Longevity; Male; Mice; Mice, Inbred CBA; p-Fluorophenylalanine; Phenylalanine; Proteins | 1978 |
Post-natal changes in the transport of aromatic amino acids into the brain [proceedings].
Topics: Aging; Amino Acids; Animals; Biological Transport; Brain; Phenylalanine; Rats; Tryptophan; Tyrosine | 1978 |
Testing the protein error hypothesis of ageing in Drosophila.
Topics: Aging; Animals; Drosophila melanogaster; Ethionine; Half-Life; Male; Phenylalanine; Proteins; Tryptophan; Tyrosine | 1976 |
Age-related changes of accuracy and efficiency of protein synthesis machinery in rat.
Topics: Aging; Animals; Carbon Radioisotopes; Isotope Labeling; Kinetics; Leucine; Liver; Phenylalanine; Poly U; Protein Biosynthesis; Rats; Ribosomes; Tritium | 1977 |
On the etiology of aging.
Topics: Aging; Amino Acids; Aspartic Acid; Half-Life; Humans; Isomerism; Phenylalanine; Proteins; Thermodynamics | 1977 |
[Age dependent changes of biosynthesis of proteins (author's transl)].
Topics: Aging; Animals; Cytosol; Kidney; Liver; Phenylalanine; Poly U; Protein Biosynthesis; Rats; Ribosomal Proteins; RNA, Ribosomal | 1976 |
The effect of experimental hyperphenylalaninaemia on polyribosomes of the developing rat brain.
Topics: Aging; Animals; Brain; Phenylalanine; Polyribosomes; Rats; Ultracentrifugation | 1975 |
The effect of ageing on in vitro fidelity of translation in mouse liver.
Topics: Aging; Animals; Leucine; Liver; Magnesium; Mice; Microsomes, Liver; Phenylalanine; Poly U; Protein Biosynthesis | 1975 |
The mechanism of polyribosome disaggregation in brain tissue by phenylalanine.
Topics: Aging; Animals; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Mice; Phenylalanine; Polyribosomes; Potassium Chloride; Ribosomal Proteins; Ribosomes | 1975 |
Role of ribonuclease action in phenylalanine-induced disaggregation of rat cerebral polyribosomes.
Topics: Aging; Amino Acids; Animals; Binding Sites; Brain; Cell Fractionation; Kinetics; Liver; Male; Nerve Tissue Proteins; Organ Specificity; Phenylalanine; Polyribosomes; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes | 1976 |
Dependency on the source of supernatant factors for optimal 14C-polyphenylalanine synthesis by high-salt wash treated liver ribosomal subunits in rats of different ages.
Topics: Aging; Animals; In Vitro Techniques; Liver; Male; Peptide Biosynthesis; Peptides; Phenylalanine; Potassium Chloride; Protein Biosynthesis; Rats; Ribosomes | 1976 |
Age-dependent decrease in the amount of eukaryotic initiation factor 2 in various rat tissues.
Topics: Aging; Animals; Brain; Eukaryotic Initiation Factor-2; Kidney; Liver; Lung; Male; Organ Size; Organ Specificity; Phenylalanine; Protein Biosynthesis; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Spleen; Tritium | 1992 |
Effects of aging and dietary restriction on tissue protein synthesis: relationship to plasma insulin-like growth factor-1.
Topics: Aging; Animals; Diaphragm; Diet; Insulin-Like Growth Factor I; Liver; Male; Mice; Mice, Inbred C57BL; Myocardium; Phenylalanine; Protein Biosynthesis; Specific Pathogen-Free Organisms; Time Factors; Tissue Distribution; Tyrosine | 1992 |
Myelin turnover in hyperphenylalaninaemia. A re-evaluation with the HPH-5 mouse.
Topics: Aging; Amino Acids; Animals; Body Weight; Brain; Half-Life; Mice; Mice, Mutant Strains; Myelin Proteins; Myelin Sheath; Organ Size; Phenylalanine; Phenylalanine Hydroxylase | 1992 |
Accelerated ribosome formation and growth in neonatal pig hearts.
Topics: Aging; Animals; Animals, Newborn; Cell Fractionation; Centrifugation, Density Gradient; Heart; Heart Ventricles; Myocardium; Phenylalanine; Protein Biosynthesis; Ribosomes; RNA; Swine | 1990 |
Protein synthesis in adult skeletal muscle after tenotomy: responses to fasting and insulin infusion.
Topics: Aging; Animals; Blood Glucose; Fasting; Female; Hindlimb; Insulin; Muscle Proteins; Muscles; Phenylalanine; Rats; Ribosomes; RNA; Tendons | 1991 |
Delayed plasma clearance of phenylalanine and tyrosine in elderly men.
Topics: Adult; Aged; Aging; Amino Acids; Dementia; Enteral Nutrition; Humans; Middle Aged; Phenylalanine; Tyrosine | 1991 |
Stage of development and fasting affect protein synthetic activity in the gastrointestinal tissues of suckling rats.
Topics: Aging; Animals; Animals, Suckling; Chromatography, High Pressure Liquid; Fasting; Gastric Mucosa; Intestine, Small; Pancreas; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1991 |
Six-year follow up of phenylalanine intakes and plasma phenylalanine concentrations.
Topics: Aging; Female; Follow-Up Studies; Humans; Infant, Newborn; Male; Patient Compliance; Phenylalanine; Phenylketonurias | 1990 |
Significance of the in vivo deuterated phenylalanine load for long-term phenylalanine tolerance and psycho-intellectual outcome in patients with PKU.
Topics: Aging; Humans; Infant, Newborn; Intelligence Tests; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Prospective Studies | 1990 |
EEG development in early treated PKU patients from birth to 6 years of age.
Topics: Aging; Electroencephalography; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias | 1990 |
Development of L-glutamine-stimulated electroneutral sodium absorption in piglet jejunum.
Topics: Aging; Animals; Animals, Newborn; Chlorides; Electric Conductivity; Electrophysiology; Glutamine; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mannitol; Muscle Development; Muscle, Smooth; Phenylalanine; Sodium; Swine | 1990 |
Changes in metabolite transport by small intestine and kidney of young and old rats.
Topics: Aging; Animals; Aspartic Acid; Citrates; Citric Acid; Glucose; In Vitro Techniques; Intestine, Small; Kidney Cortex; Male; Microvilli; Phenylalanine; Rats; Rats, Inbred Strains | 1990 |
Effects of aging and xerosis on the amino acid composition of human skin.
Topics: Aging; Amino Acids; Female; Filaggrin Proteins; Glycine; Humans; Ichthyosis; Leucine; Phenylalanine; Skin; Tyrosine | 1990 |
Protein turnover and growth of the rat brain from the foetus to old age.
Topics: Aging; Animals; Brain; DNA; Female; Fetus; Kinetics; Nerve Tissue Proteins; Phenylalanine; Pregnancy; Rats; RNA | 1988 |
Characterization of elevated plasma alkaline phosphatase activity in genetically obese mice.
Topics: Aging; Alkaline Phosphatase; Animals; Drug Interactions; Homoarginine; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Obesity; Phenylalanine | 1985 |
Development of adenosine 5'-triphosphate sulfurylase and adenosine phosphosulfate kinase in rat cerebrum and liver.
Topics: Aging; Animals; Brain; Liver; Nucleotidyltransferases; Phenylalanine; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Inbred Strains; Sulfate Adenylyltransferase | 1987 |
The poly(U) translational capacity of Fischer 344 rat liver does not deteriorate with age and is not affected by dietary regime.
Topics: Aging; Animals; Diet; In Vitro Techniques; Liver; Male; Phenylalanine; Poly U; Protein Biosynthesis; Rats; Rats, Inbred F344; Ribosomes | 1988 |
Fidelity of aminoacylation by rat-liver tyrosyl-tRNA synthetase. Effect of age.
Topics: Acylation; Age Factors; Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Binding, Competitive; Biological Transport; Electrophoresis, Polyacrylamide Gel; Liver; Male; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred F344; RNA, Transfer; Tyrosine; Tyrosine-tRNA Ligase | 1988 |
The development of the muscarinic acetylcholine receptor in normal and hyperphenylalaninemic rat cerebrum.
Topics: Aging; Animals; Brain; Phenylalanine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Raman spectroscopic evaluation of aging and long-wave UV exposure in the guinea pig lens: a possible model for human aging.
Topics: Aging; Animals; Disulfides; Guinea Pigs; Lens, Crystalline; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Sulfhydryl Compounds; Tryptophan; Tyrosine; Ultraviolet Rays | 1988 |
Effect of aging on intestinal absorption of aromatic amino acids in vitro in the rat.
Topics: Aging; Animals; In Vitro Techniques; Intestinal Absorption; Jejunum; Kinetics; Male; Phenylalanine; Rats; Rats, Inbred F344; Tryptophan; Tyrosine | 1988 |
Growth hormone restores protein synthesis in skeletal muscle of old male rats.
Topics: Age Factors; Aging; Animals; Diaphragm; Growth Hormone; Levodopa; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains | 1985 |
Protein turnover and cathepsin B activity in several individual tissues of foetal and senescent rats.
Topics: Aging; Animals; Cathepsin B; Cathepsins; Female; Fetus; Gestational Age; Male; Phenylalanine; Pregnancy; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1985 |
Effect of para-chlorophenylalanine on the growth and development of the fetal, neonatal, and adult rat.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Feeding Behavior; Female; Fenclonine; Fetus; Gestational Age; Male; Organ Size; Phenylalanine; Pregnancy; Rats; Time Factors | 1970 |
Effect of p-chlorophenylalanine and L-phenylalanine on deoxyribonucleic acid and protein content of developing rat cerebellum.
Topics: Aging; Animals; Body Weight; Brain Chemistry; Cerebellum; DNA; Female; Fenclonine; Nerve Tissue Proteins; Phenylalanine; Rats; Time Factors | 1974 |
Activity of the phenylalanine hydroxylating system in liver of newborn, suckling and adult rats.
Topics: Aging; Aldehydes; Animals; Animals, Newborn; Body Weight; Carbon Isotopes; Female; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; Organ Size; Phenylalanine; Proteins; Rats; Tyrosine | 1969 |
Effect of hyperphenylalaninemia on fatty acid composition of lipids of rat brain myelin.
Topics: Aging; Aldehydes; Animals; Brain Chemistry; Cerebrosides; Chromatography, Gas; Chromatography, Thin Layer; Esters; Fatty Acids; Glycolipids; Lipids; Myelin Sheath; Nerve Tissue Proteins; Phenylalanine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingolipids; Sphingomyelins; Time Factors | 1973 |
Aromatic amino acid metabolism in the wabbler-lethal mouse.
Topics: Aging; Animals; Liver; Mice; Mixed Function Oxygenases; Nervous System Diseases; Phenylalanine; Rodent Diseases; Transaminases; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase | 1969 |
Measurements of rates of protein synthesis in rat brain slices.
Topics: Aging; Amino Acids; Animals; Brain; Carbon Radioisotopes; Histidine; In Vitro Techniques; Kinetics; Leucine; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Time Factors; Tritium; Valine | 1974 |
Error accumulation and aging in human diploid cells.
Topics: Aging; Carbon Radioisotopes; Cell Division; Cell Line; Cells, Cultured; Culture Media; Depression, Chemical; Diploidy; DNA; Dose-Response Relationship, Drug; Ethionine; Humans; Hydrocarbons, Fluorinated; Lung; Macromolecular Substances; Phenylalanine; Protein Biosynthesis | 1974 |
Fetal development: the effects of maturation on in vitro protein synthesis by mouse brain tissue.
Topics: Aging; Animals; Animals, Newborn; Arginine; Brain; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Deoxycholic Acid; Female; Fetus; Gestational Age; In Vitro Techniques; Magnesium; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phenylalanine; Polyribosomes; Pregnancy; Time Factors | 1974 |
Muscle protein synthesis during development of the normal and dystrophic chicken. Activity of supernatant elongation factors.
Topics: Acyltransferases; Aging; Animals; Carbon Radioisotopes; Chick Embryo; Chickens; Chromatography, Ion Exchange; Cytosol; Ethylmaleimide; Hydroxyapatites; Leucine; Muscle Development; Muscle Proteins; Muscles; Muscular Dystrophy, Animal; Peptide Elongation Factors; Phenylalanine; Ribosomes; RNA, Transfer; Spectrophotometry, Ultraviolet; Time Factors; Transfer RNA Aminoacylation | 1974 |
Intestinal absorption of some heterocyclic and aromatic amino acids from the ageing gut.
Topics: Aging; Animals; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver; Organ Size; Phenylalanine; Proline; Rats; Tryptophan | 1974 |
The use of aminoacyl-tRNA to measure polypeptide synthesis by ribosomes isolated from neonatal and adult mouse brain tissue.
Topics: Aging; Animals; Animals, Newborn; Anti-Bacterial Agents; Brain; Diphtheria Toxin; Escherichia coli; Ethylmaleimide; Fusidic Acid; Mice; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptides; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Tritium; Uracil Nucleotides | 1972 |
Intestinal absorption of aromatic amino acids in senescence.
Topics: Aging; Amino Acids; Animals; Indicator Dilution Techniques; Intestinal Absorption; Phenylalanine; Protein-Losing Enteropathies; Rats; Tryptophan | 1972 |
[Some aspects of protein synthesis in the thoracic muscles in the development of Schistocerca gregaria (Forsk.)].
Topics: Aging; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cycloheximide; Grasshoppers; Guanosine Triphosphate; Larva; Microsomes; Muscle Proteins; Muscles; Pancreas; Phenylalanine; Poly U; Polyribosomes; Puromycin; Ribonucleases; RNA; Stimulation, Chemical; Thorax; Trypsin | 1972 |
[Amino acid absorption in the aged].
Topics: Age Factors; Aging; Amino Acids; Animals; Carbohydrate Metabolism; Female; Intestinal Absorption; Phenylalanine; Rats; Tryptophan; Vitamins | 1973 |
Relationship of protein metabolism to senescence of corn (Zea mays L.) stalk parenchyma, cob parenchyma and first developed leaf tissues.
Topics: Aging; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cell Count; Chromatography; Dactinomycin; Glutamine; Leucine; Models, Biological; Ornithine; Phenylalanine; Plant Proteins; Plants; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Threonine; Time Factors; Tyrosine | 1973 |
A study of golden hamster (Cricetus cricetus) alkaline phosphatase isoenzymes.
Topics: Aging; Alkaline Phosphatase; Aminocaproates; Animals; Bone and Bones; Cricetinae; Drug Stability; Fluorescence; Guanidines; Hot Temperature; Humans; Intestines; Isoenzymes; Liver; Phenylalanine; Species Specificity | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Protein synthesis and loss of viability in rye embryos. The lability of transferase enzymes during senscence.
Topics: Acyltransferases; Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Carbon Radioisotopes; Cell-Free System; Edible Grain; Ethylmaleimide; Guanosine Triphosphate; Kinetics; Peptide Chain Elongation, Translational; Phenylalanine; Plant Proteins; Potassium; Ribosomes; RNA, Transfer; Seeds | 1973 |
Lipid metabolism in liver and brain in acute hyperphenylalaninemia in rats of different ages. Correlation with tissue phenylalanine and tyrosine levels.
Topics: Acetates; Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Cholesterol; Chromatography, Thin Layer; Female; Glycolipids; Lipid Metabolism; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phospholipids; Rats; Time Factors; Tyrosine | 1974 |
Arterial mesenchyme and arteriosclerosis. Enzymic vs non-enzymic factors in the deterioration of connective tissue.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Blood Platelets; Cattle; Child; Collagen; Connective Tissue; Culture Techniques; Elastic Tissue; Elastin; Female; Fluorescence; Humans; Leukocytes; Male; Middle Aged; Pancreatic Elastase; Phenylalanine; Pregnancy; Proteins; Solubility; Tyrosine; Ultraviolet Rays; X-Ray Diffraction | 1974 |
Effect of prolonged phenylalanine loading on the free amino-acid and lipid content of the infant monkey brain.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Blood-Brain Barrier; Brain Chemistry; Cerebrosides; Haplorhini; Lipids; Male; Organ Size; Phenylalanine | 1966 |
[Biochemical studies on the age-related variations of the human intervertebral disc].
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography; Collagen; Galactosamine; Glucosamine; Hexosamines; Humans; Infant; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Phenylalanine; Potassium; Sodium; Thoracic Vertebrae; Tryptophan; Tyrosine | 1972 |
A possible age-related modification of phenylalanine transfer RNA from wheat tissue.
Topics: Aging; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Phenylalanine; RNA, Transfer; Spectrometry, Fluorescence; Triticum | 1972 |
Adequate phenylalanine intake for optimum growth and development in the treatment of phenylketonuria.
Topics: Age Factors; Aging; Body Height; Body Weight; Cephalometry; Child; Child Development; Child, Preschool; Diet Therapy; Dietary Proteins; Humans; Infant; Intelligence Tests; Nutritional Requirements; Phenylalanine; Phenylketonurias | 1971 |
Serum alkaline phosphatase activity in cattle.
Topics: Abomasum; Aging; Alkaline Phosphatase; Animals; Bone and Bones; Brain; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Deficiency Diseases; Diarrhea; Duodenum; Female; Hydrogen-Ion Concentration; Isoenzymes; Kidney; Kinetics; Liver; Lung; Mammary Glands, Animal; Nitrophenols; Phenolphthaleins; Phenols; Phenylalanine; Phosphoric Acids; Placenta; Rumen; Spleen; Urea | 1971 |
Preparation of two antigens of human liver isoenzymes of alkaline phosphatase.
Topics: Aging; Alkaline Phosphatase; Antibody Formation; Antigens; Arginine; Chromatography, Gel; Depression, Chemical; Humans; Immune Sera; Immunoelectrophoresis; Isoenzymes; Liver; Magnesium; Phenylalanine; Stimulation, Chemical | 1971 |
Solubilization of a reticulocyte ribosomal fraction responsible for the decline in ribosomal activity with cell maturation.
Topics: Aging; Animals; Blood Proteins; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Chlorides; Deuterium; Electrophoresis; Hemoglobins; Leucine; Magnesium; Phenylalanine; Polynucleotides; Potassium Chloride; Reticulocytes; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Viral; Serum Albumin, Bovine; Solubility; Spectrophotometry; Time Factors; Tritium; Ultraviolet Rays; Uracil Nucleotides | 1971 |
Alteration in microsomal protein synthesis during early development of mouse brain.
Topics: Aging; Animals; Brain; Centrifugation, Density Gradient; Ligases; Mice; Microsomes; Phenylalanine; Protein Biosynthesis; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Transfer; Tritium | 1969 |
Inhibition of human brain pyruvate kinase and hexokinase by phenylalanine and phenylpyruvate: possible relevance to phenylketonuric brain damage.
Topics: Aging; Animals; Brain; Fetus; Gestational Age; Hexokinase; Humans; In Vitro Techniques; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pyruvate Kinase; Rats | 1969 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Absence of a life-shortening effect of amino-acid analogues on adult Drosophila.
Topics: Aging; Amino Acids; Animals; Antimetabolites; Dietary Proteins; Drosophila; Hydrocarbons, Halogenated; Leucine; Longevity; Male; Phenylalanine; Protein Biosynthesis; Tritium | 1969 |
In vitro protein synthesis and aging in Rhizoctania solani.
Topics: Aging; Amino Acids; Carbon Isotopes; Cell-Free System; Fungi; Ligases; Peptide Biosynthesis; Phenylalanine; Ribosomes | 1970 |
Hyperphenylalaninemia: disaggregation of brain polyribosomes in young rats.
Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Cell-Free System; Centrifugation, Density Gradient; Disease Models, Animal; Humans; Injections, Intraperitoneal; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Rats; Ribosomes | 1970 |
Dietary amino acid and nucleic acid imbalance leading to altered tumour frequency in the adult housefly, Musca domestica.
Topics: Aging; Amino Acids; Animals; Dietary Proteins; Houseflies; Neoplasms; Nucleic Acids; Phenylalanine | 1968 |
Effect of the administration of xanthine on the appearance of xanthine oxidase activity in the liver of growing rats.
Topics: Aging; Animals; Carbon Isotopes; Cortisone; Cycloheximide; Dactinomycin; Leucine; Liver; Orotic Acid; Phenylalanine; Rats; RNA; Xanthine Oxidase; Xanthines | 1968 |
[Study of phenylalanine incorporation into proteins in a cell free system from chicken liver as a function of age].
Topics: Adenosine Triphosphate; Aging; Animals; Bile Acids and Salts; Carbon Isotopes; Cell-Free System; Chick Embryo; Chickens; In Vitro Techniques; Liver; Microsomes; Phenylalanine; Polynucleotides; Protein Biosynthesis; Ribosomes; RNA, Messenger; Uracil Nucleotides | 1968 |
Errors in protein synthesis and clonal senescence in fungi.
Topics: Adenine; Aging; Ascomycota; Culture Media; Fluorouracil; Genetic Code; Genetics, Microbial; Mutation; Neurospora; Phenotype; Phenylalanine; Protein Biosynthesis; RNA; Suppression, Genetic | 1969 |
Characterization of placental isoenzyme of alkaline phosphatase in human pregnancy serum.
Topics: Aging; Alkaline Phosphatase; Blood Protein Electrophoresis; Delivery, Obstetric; Female; Hot Temperature; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Isoenzymes; Neuraminidase; Phenylalanine; Placenta; Pregnancy; Umbilical Cord; Vibrio | 1969 |
Polyribosome concentration of mouse skeletal muscle as a function of age.
Topics: Aging; Animals; Brain; Centrifugation, Density Gradient; Enzymes; Hydrogen-Ion Concentration; Liver; Mice; Microsomes; Muscles; Phenylalanine; Polynucleotides; Potassium Chloride; Protein Biosynthesis; Ribonucleases; Ribosomes; RNA; Uracil Nucleotides | 1969 |
Hyperphenylalaninemia: effect on the developing rat brain.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Humans; Injections, Subcutaneous; Lipid Metabolism; Liver; Mixed Function Oxygenases; Myelin Sheath; Organ Size; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1969 |
The effect of age on protein synthesis in mouse liver.
Topics: Aging; Animals; Carbon Isotopes; Cell Nucleus; Chromatography, Gel; In Vitro Techniques; Liver; Mice; Microsomes; Phenylalanine; Polynucleotides; Protein Biosynthesis; RNA, Messenger; Surface-Active Agents; Ultracentrifugation | 1969 |
Protein synthesis in growing-rat tissues. II. Polyribosome concentration of brain and liver as a function of age.
Topics: Aging; Animals; Animals, Newborn; Brain; In Vitro Techniques; Liver; Phenylalanine; Polynucleotides; Protein Biosynthesis; Rats; Ribosomes; Uracil Nucleotides | 1966 |
Biochemistry of the developing rat brain. 8. Changes in the ribosomal system and nuclear RNA's.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell Nucleus; Hydrogen-Ion Concentration; Lysine; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA; RNA, Messenger; Ultracentrifugation; Ultraviolet Rays | 1966 |
Brain amines and brain weights in growing chicks: some normal values and effects of feeding excess dietary l-phenylalanine.
Topics: Aging; Animals; Body Weight; Brain; Brain Chemistry; Diet; Female; Male; Norepinephrine; Organ Size; Phenylalanine; Poultry; Serotonin | 1966 |