phenylacetic acid has been researched along with Propionic Acidemia in 1 studies
phenylacetic acid : A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.
Propionic Acidemia: Autosomal recessive metabolic disorder caused by mutations in PROPIONYL-COA CARBOXYLASE genes that result in dysfunction of branch chain amino acids and of the metabolism of certain fatty acids. Neonatal clinical onset is characterized by severe metabolic acidemia accompanied by hyperammonemia, HYPERGLYCEMIA, lethargy, vomiting, HYPOTONIA; and HEPATOMEGALY. Survivors of the neonatal onset propionic acidemia often show developmental retardation, and intolerance to dietary proteins. Late-onset form of the disease shows mild mental and/or developmental retardation, sometimes without metabolic acidemia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armstrong, AJ | 1 |
| Henke, BR | 1 |
| Collado, MS | 1 |
| Taylor, JM | 1 |
| Pourtaheri, TD | 1 |
| Dillberger, JE | 1 |
| Roper, TD | 1 |
| Wamhoff, BR | 1 |
| Olson, MW | 1 |
| Figler, RA | 1 |
| Hoang, SA | 1 |
| Reardon, JE | 1 |
| Johns, BA | 1 |
1 other study available for phenylacetic acid and Propionic Acidemia
| Article | Year |
|---|---|
Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.
Topics: Acyl Coenzyme A; Amino Acid Metabolism, Inborn Errors; Animals; Area Under Curve; Butyrates; Cells, | 2021 |