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phenylacetic acid and Coma

phenylacetic acid has been researched along with Coma in 4 studies

phenylacetic acid : A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
" Therefore, we used magnetic resonance spectroscopy (MRS) to monitor cerebral glutamine levels, the major reservoir of ammonia, in a gastric bypass patient with hyperammonemic coma undergoing therapy with N-carbamoyl glutamate and the ammonia-scavenging agents, sodium phenylacetate and sodium benzoate."7.85Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma. ( Bellinger, A; Berry, GT; Cohen, DE; Frank, NY; Gershanik, EF; Goldberg, AD; Levy, BD; Lin, AP; Lynch, R; McFaline-Figueroa, JR; Merugumala, SK; O'Donnell-Luria, AH; Rohr, F; Samuels, MA; Simon, T; Tchekmedyian, V; Waisbren, SE, 2017)
" Therefore, we used magnetic resonance spectroscopy (MRS) to monitor cerebral glutamine levels, the major reservoir of ammonia, in a gastric bypass patient with hyperammonemic coma undergoing therapy with N-carbamoyl glutamate and the ammonia-scavenging agents, sodium phenylacetate and sodium benzoate."3.85Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma. ( Bellinger, A; Berry, GT; Cohen, DE; Frank, NY; Gershanik, EF; Goldberg, AD; Levy, BD; Lin, AP; Lynch, R; McFaline-Figueroa, JR; Merugumala, SK; O'Donnell-Luria, AH; Rohr, F; Samuels, MA; Simon, T; Tchekmedyian, V; Waisbren, SE, 2017)
"When patients present in hyperammonemic coma, the urea cycle disorders should be considered, especially if no obvious cause is identified."2.38Late clinical presentation of partial carbamyl phosphate synthetase I deficiency. ( Klinger, RJ; Lo, WD; Sloan, HR; Sotos, JF, 1993)
"Lethal hyperammonemic coma has been reported in 2 adults after lung transplantation."1.30Successful use of alternate waste nitrogen agents and hemodialysis in a patient with hyperammonemic coma after heart-lung transplantation. ( Berry, GT; Bridges, ND; Clancy, RR; Kaplan, P; Lichtenstein, GR; Nathanson, KL; Spray, TL, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Donnell-Luria, AH1
Lin, AP1
Merugumala, SK1
Rohr, F1
Waisbren, SE1
Lynch, R1
Tchekmedyian, V1
Goldberg, AD1
Bellinger, A1
McFaline-Figueroa, JR1
Simon, T1
Gershanik, EF1
Levy, BD1
Cohen, DE1
Samuels, MA1
Berry, GT2
Frank, NY1
Lo, WD1
Sloan, HR1
Sotos, JF1
Klinger, RJ1
Bridges, ND1
Nathanson, KL1
Kaplan, P1
Clancy, RR1
Lichtenstein, GR1
Spray, TL1
Oliver, RM1
Talbot, S1
Raman, GV1

Reviews

1 review available for phenylacetic acid and Coma

ArticleYear
Late clinical presentation of partial carbamyl phosphate synthetase I deficiency.
    American journal of diseases of children (1960), 1993, Volume: 147, Issue:3

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Ammonia; Benzoates; Benzoic Acid; Biopsy; Body Hei

1993

Other Studies

3 other studies available for phenylacetic acid and Coma

ArticleYear
Brain MRS glutamine as a biomarker to guide therapy of hyperammonemic coma.
    Molecular genetics and metabolism, 2017, Volume: 121, Issue:1

    Topics: Brain; Coma; Female; Gastric Bypass; Glutamates; Glutamine; Humans; Hyperammonemia; Magnetic Resonan

2017
Successful use of alternate waste nitrogen agents and hemodialysis in a patient with hyperammonemic coma after heart-lung transplantation.
    Archives of neurology, 1999, Volume: 56, Issue:4

    Topics: Adult; Amino Acids; Ammonia; Antimetabolites, Antineoplastic; Brain Diseases; Coma; Edema; Female; H

1999
Hyperammonaemic coma in ureterosigmoid urinary diversion.
    Postgraduate medical journal, 1989, Volume: 65, Issue:765

    Topics: Amino Acids; Ammonia; Benzoates; Benzoic Acid; Colon, Sigmoid; Coma; Female; Humans; Middle Aged; Ph

1989