phenylacetic acid has been researched along with Breast Cancer in 15 studies
phenylacetic acid : A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To relate paraoxonase (PON1) activity to survival time and short term death in breast cancer recurrence." | 7.78 | Paraoxonase 1 (PON1) as a marker of short term death in breast cancer recurrence. ( Bard, JM; Bobin-Dubigeon, C; Campone, M; Classe, JM; Hervé, M; Jaffré, I; Joalland, MP, 2012) |
| "To relate paraoxonase (PON1) activity to survival time and short term death in breast cancer recurrence." | 3.78 | Paraoxonase 1 (PON1) as a marker of short term death in breast cancer recurrence. ( Bard, JM; Bobin-Dubigeon, C; Campone, M; Classe, JM; Hervé, M; Jaffré, I; Joalland, MP, 2012) |
| "When breast cancer cells were treated with NaPa in the presence of an MMP inhibitor (GM6001), apoptotic cell death decreased and the induction of autophagic vacuoles in MDA-MB-231 cells was inhibited." | 1.35 | Matrix metalloproteinases are involved in both type I (apoptosis) and type II (autophagy) cell death induced by sodium phenylacetate in MDA-MB-231 breast tumour cells. ( Augustin, S; Berard, M; Crépin, M; Fauvel-Lafève, F; He, L; Kellaf, S; Legrand, C; Peyri, N, 2009) |
| "MCF-7 breast cancer cells were used in this study." | 1.34 | Modulation by phenylacetate of early estrogen-mediated events in MCF-7 breast cancer cells. ( Li, J; Liu, J; Sidell, N, 2007) |
| "Using the highly invasive breast cancer cell line MDA-MB-231, we demonstrated that an 18-hour incubation with NaPa strongly inhibits the cell invasiveness through Matrigel (86% inhibition at 20 mM of NaPa)." | 1.31 | Decrease of breast cancer cell invasiveness by sodium phenylacetate (NaPa) is associated with an increased expression of adhesive molecules. ( Crépin, M; Legrand, E; Paysant, J; Soria, C; Thibout, D; Vasse, M, 2001) |
| "Using a highly tumorigenic human breast cancer model (Ha-ras-transfected MCF7 cell line) we analyzed the efficacy of the differentiation-inducing agent sodium phenylacetate (NaPA), both in vitro and in vivo." | 1.29 | Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7ras cells in vitro and in nude mice. ( Adam, L; Crépin, M; Israël, L; Savin, C, 1995) |
| "Using human breast carcinoma MCF-7 cells as a model, we show here that PA-induced growth arrest is associated with enhanced expression of the cyclin-dependent kinase inhibitor p21Waf1/Cip1 and dephosphorylation of the retinoblastoma protein (pRB)." | 1.29 | Up-regulation and functional role of p21Waf1/Cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate. ( Gorospe, M; Guyton, KZ; Holbrook, NJ; Samid, D; Shack, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 11 (73.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, M | 1 |
| Miyajima, N | 1 |
| Igarashi, M | 1 |
| Endo, Y | 1 |
| Watanabe, N | 1 |
| Sugano, S | 1 |
| Augustin, S | 1 |
| Berard, M | 1 |
| Kellaf, S | 1 |
| Peyri, N | 1 |
| Fauvel-Lafève, F | 1 |
| Legrand, C | 1 |
| He, L | 1 |
| Crépin, M | 7 |
| Ho, KK | 1 |
| Rosivatz, E | 2 |
| Gunn, RM | 1 |
| Smith, ME | 1 |
| Stavropoulou, AV | 1 |
| Numbere, MG | 1 |
| Wong, JB | 1 |
| Lafitte, VG | 1 |
| Behrendt, JM | 1 |
| Myatt, SS | 1 |
| Hailes, HC | 1 |
| Woscholski, R | 1 |
| Lam, EW | 1 |
| Bobin-Dubigeon, C | 1 |
| Jaffré, I | 1 |
| Joalland, MP | 1 |
| Classe, JM | 1 |
| Campone, M | 1 |
| Hervé, M | 1 |
| Bard, JM | 1 |
| Burgermeister, E | 1 |
| Tencer, L | 1 |
| Liscovitch, M | 1 |
| Liu, J | 1 |
| Li, J | 1 |
| Sidell, N | 2 |
| Adam, L | 2 |
| Savin, C | 1 |
| Israël, L | 2 |
| Gorospe, M | 1 |
| Shack, S | 1 |
| Guyton, KZ | 1 |
| Samid, D | 2 |
| Holbrook, NJ | 1 |
| Vasse, M | 1 |
| Thibout, D | 1 |
| Paysant, J | 1 |
| Legrand, E | 1 |
| Soria, C | 1 |
| Artemov, D | 1 |
| Solaiyappan, M | 1 |
| Bhujwalla, ZM | 1 |
| Vergote, J | 1 |
| Di Benedetto, M | 3 |
| Moretti, JL | 1 |
| Azaloux, H | 1 |
| Kouyoumdjian, JC | 1 |
| Kraemer, M | 3 |
| Sawatsri, S | 1 |
| Malkapuram, S | 1 |
| Kourbali, Y | 1 |
| Starzec, A | 2 |
| Vassy, R | 1 |
| Jozefonvicz, J | 1 |
| Perret, G | 1 |
| Colombo, BM | 1 |
| Briane, D | 1 |
| Perret, GY | 1 |
15 other studies available for phenylacetic acid and Breast Cancer
| Article | Year |
|---|---|
Sodium phenylacetate inhibits the Ras/MAPK signaling pathway to induce reduction of the c-Raf-1 protein in human and canine breast cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Differentiation; | 2009 |
Matrix metalloproteinases are involved in both type I (apoptosis) and type II (autophagy) cell death induced by sodium phenylacetate in MDA-MB-231 breast tumour cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Blotting, Western; Breast Neoplasms; Cell Cul | 2009 |
The novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells.
Topics: Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Enzyme Inhibitors; Female; Fibroblasts; Hum | 2009 |
Paraoxonase 1 (PON1) as a marker of short term death in breast cancer recurrence.
Topics: Adult; Aryldialkylphosphatase; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Enzym | 2012 |
Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
Topics: Adenocarcinoma; Antigens, Differentiation; Antigens, Neoplasm; Breast Neoplasms; Caveolin 1; Caveoli | 2003 |
Modulation by phenylacetate of early estrogen-mediated events in MCF-7 breast cancer cells.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent | 2007 |
Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7ras cells in vitro and in nude mice.
Topics: Animals; Apoptosis; Breast Neoplasms; Down-Regulation; Female; Genes, ras; Growth Inhibitors; Humans | 1995 |
Up-regulation and functional role of p21Waf1/Cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate.
Topics: Animals; Antimetabolites, Antineoplastic; Antisense Elements (Genetics); Breast Neoplasms; Calcium-C | 1996 |
Tumor growth inhibition, apoptosis, and Bcl-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineopl | 1997 |
Decrease of breast cancer cell invasiveness by sodium phenylacetate (NaPa) is associated with an increased expression of adhesive molecules.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Adhesion Molecules; Humans; Neoplasm Invasiveness; Phe | 2001 |
Magnetic resonance pharmacoangiography to detect and predict chemotherapy delivery to solid tumors.
Topics: Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carbon Isotopes; Contrast Media; Drug Mo | 2001 |
Could 99mTc-MIBI be used to visualize the apoptotic MCF7 human breast cancer cells?
Topics: Apoptosis; Breast Neoplasms; Cell Division; DNA; Female; Humans; Phenylacetates; Radionuclide Imagin | 2001 |
Inhibition of estrogen-dependent breast cell responses with phenylacetate.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Division; Cyclin D1; Dose-Response Relations | 2001 |
Sodium phenylacetate enhances the inhibitory effect of dextran derivative on breast cancer cell growth in vitro and in nude mice.
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Cycle; Cell Division; Ce | 2001 |
Aponecrotic, antiangiogenic and antiproliferative effects of a novel dextran derivative on breast cancer growth in vitro and in vivo.
Topics: 3T3 Cells; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Culture Media, | 2002 |