phenylacetic acid has been researched along with B-Cell Chronic Lymphocytic Leukemia in 3 studies
phenylacetic acid : A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The goals of this study were to determine whether PA and PB (a) are cytotoxic to malignant B cells from patients with non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukemia and (b) exhibit additive or synergistic induction of apoptosis when administered to myeloma cell lines in combination with conventional drugs." | 1.31 | Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents. ( Kaufmann, SH; Stenson, M; Svingen, PA; Timm, M; Witzig, TE, 2000) |
| " The mean distribution half-life of chlorambucil was 0." | 1.31 | Pharmacokinetics of chlorambucil in patients with chronic lymphocytic leukaemia: comparison of different days, cycles and doses. ( Malminiemi, K; Malminiemi, O; Seppälä, E; Silvennoinen, R; Vilpo, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Call, TG | 1 |
| Stenson, MJ | 1 |
| Witzig, TE | 2 |
| Timm, M | 1 |
| Stenson, M | 1 |
| Svingen, PA | 1 |
| Kaufmann, SH | 1 |
| Silvennoinen, R | 1 |
| Malminiemi, K | 1 |
| Malminiemi, O | 1 |
| Seppälä, E | 1 |
| Vilpo, J | 1 |
3 other studies available for phenylacetic acid and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Effects of phenylacetate on cells from patients with B-chronic lymphocytic leukemia.
Topics: Acid Phosphatase; B-Lymphocytes; Cell Differentiation; Cell Survival; Drug Screening Assays, Antitum | 1994 |
Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cell Survival; Drug Interactions; Drug Synergism; H | 2000 |
Pharmacokinetics of chlorambucil in patients with chronic lymphocytic leukaemia: comparison of different days, cycles and doses.
Topics: Administration, Oral; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylat | 2000 |