Compounds > phenyl-n-tert-butylnitrone

phenyl-n-tert-butylnitrone and Retinal Degeneration

phenyl-n-tert-butylnitrone has been researched along with Retinal Degeneration in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cercy, C; Choteau, F; Durand, G; Pucci, B; Ranchon-Cole, I1
Anderson, RE; Chen, H; Elliott, MH; Floyd, RA; Kasus-Jacobi, A; Li, X; Ma, JX; Mandal, MN; Moiseyev, GP; Nikolaeva, O; Zheng, L1
Anderson, RE; Kotake, Y; LaVail, MM; Ranchon, I1
Anderson, RE; Kotake, Y; Tomita, H1
Anderson, RE; Elliott, MH; Kotake, Y; Tanito, M1
Jeong, SM; Kim, JH; Kim, KW; Yu, YS1
Anderson, RE; Kaidzu, S; Tanito, M1
Bedker, DA; Castagné, V; Clarke, PG; Lefèvre, K; Natero, R1
Alvarez, K; Anderson, RE; Chen, S; Ranchon, I1

Other Studies

9 other study(ies) available for phenyl-n-tert-butylnitrone and Retinal Degeneration

ArticleYear
Cholesterol-based α-phenyl-N-tert-butyl nitrone derivatives as antioxidants against light-induced retinal degeneration.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Animals; Antioxidants; Cholesterol; Cyclic N-Oxides; Disaccharides; Imines; Light; Rats; Reactive Oxygen Species; Retinal Degeneration; Retinal Diseases

2010
Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity.
    The Journal of biological chemistry, 2011, Sep-16, Volume: 286, Issue:37

    Topics: Acyltransferases; Alcohol Oxidoreductases; Animals; Carrier Proteins; cis-trans-Isomerases; Cyclic N-Oxides; Eye Proteins; Light; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Rhodopsin

2011
Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jul-09, Volume: 23, Issue:14

    Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Cyclic N-Oxides; Disease Models, Animal; Electroretinography; Free Radical Scavengers; Genetic Predisposition to Disease; Light; Mutation; Nitrogen Oxides; Photic Stimulation; Photoperiod; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Rhodopsin; Sensory Thresholds; Treatment Outcome

2003
Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:2

    Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspases; Cyclic N-Oxides; DNA Fragmentation; Fas Ligand Protein; Female; Free Radical Scavengers; In Situ Nick-End Labeling; Light; Male; Membrane Glycoproteins; Neuroprotective Agents; Nitrogen Oxides; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fos; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; RNA, Messenger; Transcription Factor AP-1; Up-Regulation

2005
Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:10

    Topics: Aldehydes; Animals; Apoptosis; Blotting, Western; Cyclic N-Oxides; Eye Proteins; Female; Free Radical Scavengers; Immunoenzyme Techniques; In Situ Nick-End Labeling; Light; Nitrogen Oxides; Protein Processing, Post-Translational; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration

2005
Delay of photoreceptor cell degeneration in rd mice by systemically administered phenyl-N-tert-butylnitrone.
    Korean journal of ophthalmology : KJO, 2005, Volume: 19, Issue:4

    Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Enzyme Precursors; Female; Follow-Up Studies; Free Radical Scavengers; Injections, Intraperitoneal; Male; Mice; Neuroprotective Agents; Nitrogen Oxides; Photoreceptor Cells, Vertebrate; Pigment Epithelium of Eye; Retinal Degeneration

2005
Delayed loss of cone and remaining rod photoreceptor cells due to impairment of choroidal circulation after acute light exposure in rats.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:4

    Topics: Aldehydes; Animals; Apoptosis; Blood Circulation; Blotting, Western; Carrier Proteins; Choroid; cis-trans-Isomerases; Cyclic N-Oxides; Electroretinography; Eye Proteins; Free Radical Scavengers; In Situ Nick-End Labeling; Light; Lipid Peroxidation; Neuroprotective Agents; Oxidative Stress; Photoreceptor Cells, Vertebrate; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Rhodopsin

2007
An optimal redox status for the survival of axotomized ganglion cells in the developing retina.
    Neuroscience, 1999, Volume: 93, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Axotomy; Azulenes; Cell Count; Cell Survival; Chick Embryo; Cyclic N-Oxides; Eye; Neuroprotective Agents; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Retina; Retinal Degeneration; Retinal Ganglion Cells; Sesquiterpenes; Thiourea

1999
Systemic administration of phenyl-N-tert-butylnitrone protects the retina from light damage.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:6

    Topics: Animals; Cyclic N-Oxides; Electroretinography; Free Radical Scavengers; Injections, Intraperitoneal; Light; Male; Nitrogen Oxides; Radiation Injuries, Experimental; Rats; Rats, Wistar; Retina; Retinal Degeneration; Spin Labels

2001