phenyl-n-tert-butylnitrone and Reperfusion Injury

phenyl-n-tert-butylnitrone has been researched along with Reperfusion Injury in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (51.72)18.2507
2000's11 (37.93)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouajila, J; Bouskela, E; Costa, PR; Cyrino, FZ; de A Vilela, GV; Dias, AG; Kim, S; Nepveu, F1
LaManna, JC; Puchowicz, MA; Sun, X; Xu, K1
Goda, W; Hara, A; Nakashima, M; Niwa, M; Satoh, K1
Ahn, HN; Chan, PH; Chang, M; Narasimhan, P; Song, YS; Yang, J1
Ashton, T; Griffiths, RD; Jackson, MJ; McArdle, A; Pattwell, D1
Chang, YS; Choi, CW; Hwang, JH; Lee, M; Park, WS; Shin, SM1
Caudron, I; Deby, C; Deby-Dupont, G; Lamy, M; Mottart, E; Philippart, C; Pincemail, J; Serteyn, D1
Phillis, JW; Sen, S1
Pahlmark, K; Siesjö, BK1
Beal, MF; Chen, YI; Jenkins, BG; Moskowitz, MA; Panahian, N; Rosen, BR; Schulz, JB1
Bates, TE; Hillered, L; Katsura, K; Kuroda, S; Siesjö, BK1
Aronowski, J; Grotta, JC; Strong, R1
Iwai, T; Nakashima, M; Niwa, M; Uematsu, T1
Maines, MD; Panahian, N; Raju, VS1
Fujibayashi, Y; Murata, T; Omata, N; Sadato, N; Wada, Y; Waki, A; Yonekura, Y; Yoshimoto, M2
Asahi, K; Asahi, M; Lo, EH; Wang, X1
Araki, T; Asakura, H; Koshino, T; Nakai, A; Siesjö, BK; Taniuchi, Y1
Baethmann, A; Hungerhuber, E; Reulen, H; Schmid-Elsaesser, R; Zausinger, S1
Kotake, Y1
Brisson, BA; Chen, G; Janzen, EG; McCutcheon, LJ; Miller, CW2
Burton, GJ; Hung, TH; Skepper, JN1
Bobadilla, N; Pedraza-Chaverri, J; Tapia, E1
Ogawa, R; Ohnishi, ST; Ohnishi, T; Sakamoto, A1
Carney, JM; Floyd, RA1
Clough-Helfman, C; Phillis, JW2
Canivet, JL; Defechereux, T; Defraigne, JO; Franssen, C; Meurisse, M; Philippart, C; Pincemail, J1

Reviews

1 review(s) available for phenyl-n-tert-butylnitrone and Reperfusion Injury

ArticleYear
Pharmacologic properties of phenyl N-tert-butylnitrone.
    Antioxidants & redox signaling, 1999,Winter, Volume: 1, Issue:4

    Topics: Aging; Animals; Cyclic N-Oxides; Cytokines; Disease Models, Animal; Humans; In Vitro Techniques; Molecular Structure; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitrogen Oxides; Reperfusion Injury; Spin Trapping

1999

Other Studies

28 other study(ies) available for phenyl-n-tert-butylnitrone and Reperfusion Injury

ArticleYear
Alpha-phenyl-N-tert-butyl nitrone (PBN) derivatives: synthesis and protective action against microvascular damages induced by ischemia/reperfusion.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Animals; Capillaries; Chromatography, High Pressure Liquid; Cricetinae; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Indicators and Reagents; Male; Mesocricetus; Mouth Mucosa; Regional Blood Flow; Reperfusion Injury; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

2007
Decreased brainstem function following cardiac arrest and resuscitation in aged rat.
    Brain research, 2010, Apr-30, Volume: 1328

    Topics: Aging; Animals; Antioxidants; Brain Stem; Brain Stem Infarctions; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Heart Arrest; Hippocampus; Male; Mitochondria; Nerve Degeneration; Oxidative Stress; Rats; Rats, Inbred F344; Recovery of Function; Reperfusion Injury; Respiratory Insufficiency; Resuscitation; Treatment Outcome

2010
PBN fails to suppress in delayed neuronal death of hippocampal CA1 injury following transient forebrain ischemia in gerbils.
    Neuroscience letters, 2012, May-23, Volume: 517, Issue:1

    Topics: Animals; CA1 Region, Hippocampal; Cell Death; Cyclic N-Oxides; Free Radicals; Gerbillinae; Ischemic Attack, Transient; Male; Reperfusion Injury

2012
Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice.
    Journal of neurochemistry, 2013, Volume: 124, Issue:4

    Topics: Animals; Brain; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebral Cortex; Complement C3; Cyclic N-Oxides; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Glucose; Hypoxia; L-Lactate Dehydrogenase; Male; Mice; Mice, Transgenic; Nervous System Diseases; Neuroglia; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Up-Regulation

2013
Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:6

    Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Hindlimb; Hydroxybenzoates; Hydroxyl Radical; Lipids; Microdialysis; Muscle Contraction; Muscle, Skeletal; Nitrogen Oxides; Oxidants; Prostaglandins; Rats; Rats, Wistar; Reperfusion Injury; Superoxides

2003
Effects of alpha-phenyl-N-tert-butyl nitrone (PBN)on brain cell membrane function and energy metabolism during transient global cerebral hypoxia-ischemia and reoxygenation-reperfusion in newborn piglets.
    Journal of Korean medical science, 2004, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Cell Membrane; Cerebral Cortex; Cyclic N-Oxides; Hypoxia; Ischemia; Lipid Peroxidation; Neuroprotective Agents; Nitrogen Oxides; Phosphocreatine; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Swine; Time Factors

2004
[Direct approach for demonstrating free radical phenomena during equine postanesthetic myopathy: preliminary study].
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1994, Volume: 58, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Cyclic N-Oxides; Female; Free Radicals; Halothane; Horse Diseases; Horses; Muscular Diseases; Nitrogen Oxides; Reperfusion Injury; Spin Labels

1994
alpha-Phenyl-tert-butyl-nitrone (PBN) attenuates hydroxyl radical production during ischemia-reperfusion injury of rat brain: an EPR study.
    Free radical research communications, 1993, Volume: 19, Issue:4

    Topics: Animals; Chelating Agents; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Ischemic Attack, Transient; Male; Nitrogen Oxides; Pentetic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spin Labels

1993
Effects of the spin trap-alpha-phenyl-N-tert-butyl nitrone (PBN) in transient forebrain ischaemia in the rat.
    Acta physiologica Scandinavica, 1996, Volume: 157, Issue:1

    Topics: Animals; Blood Glucose; Blood Pressure; Cyclic N-Oxides; Gerbillinae; Male; Nitrogen Oxides; Prosencephalon; Rats; Rats, Wistar; Reperfusion Injury; Solubility; Spin Labels

1996
Facilitation of postischemic reperfusion with alpha-PBN: assessment using NMR and Doppler flow techniques.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2

    Topics: Animals; Blood Pressure; Brain; Brain Mapping; Carbon Dioxide; Cerebrovascular Circulation; Cyclic N-Oxides; Heart Rate; Hemodynamics; Ischemic Attack, Transient; Magnetic Resonance Spectroscopy; Male; Nitrogen Oxides; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Spin Labels; Time Factors; Ultrasonography, Doppler

1997
Delayed treatment with alpha-phenyl-N-tert-butyl nitrone (PBN) attenuates secondary mitochondrial dysfunction after transient focal cerebral ischemia in the rat.
    Neurobiology of disease, 1996, Volume: 3, Issue:2

    Topics: Adenosine Diphosphate; Animals; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cyclic N-Oxides; Energy Metabolism; Free Radical Scavengers; Male; Mitochondria; Neuroprotective Agents; Nitrogen Oxides; Oxygen Consumption; Rats; Rats, Wistar; Reperfusion Injury; Spin Labels

1996
Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:10

    Topics: Animals; Brain Diseases; Carotid Artery, Common; Cerebral Arteries; Constriction; Cyclic N-Oxides; Cycloheximide; Hypertension; Ischemic Attack, Transient; Male; Nitrogen Oxides; Protein Synthesis Inhibitors; Rats; Rats, Inbred SHR; Reperfusion Injury

1997
Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat.
    Free radical biology & medicine, 1999, Volume: 26, Issue:5-6

    Topics: Animals; Antipyrine; Brain; Caudate Nucleus; Cerebral Infarction; Cyclic N-Oxides; Disease Models, Animal; Edaravone; Free Radical Scavengers; Free Radicals; Hippocampus; Ischemic Attack, Transient; Male; Nitroarginine; Nitrogen Oxides; Putamen; Rats; Rats, Inbred F344; Rats, Wistar; Reperfusion Injury; Spin Labels; Superior Colliculi

1999
Spin trap (N-t-butyl-alpha-phenylnitrone)-mediated suprainduction of heme oxygenase-1 in kidney ischemia/reperfusion model: role of the oxygenase in protection against oxidative injury.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Animals; Antibodies; Blotting, Northern; Blotting, Western; Cyclic N-Oxides; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Iron; Isoenzymes; Kidney; Lipid Peroxidation; Nitrogen Oxides; Oxidative Stress; Oxygenases; Rats; Reperfusion Injury; RNA, Messenger; Spin Trapping; Time Factors

1999
Hypoxic but not ischemic neurotoxicity of free radicals revealed by dynamic changes in glucose metabolism of fresh rat brain slices on positron autoradiography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:2

    Topics: Animals; Autoradiography; Brain; Cerebrovascular Circulation; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fluorodeoxyglucose F18; Free Radicals; Glucose; Glutamic Acid; Hypoxia, Brain; In Vitro Techniques; Ischemic Attack, Transient; Male; Neurotoxins; Nitrogen Oxides; Oxygen; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spin Labels

2000
Reduction of tissue plasminogen activator-induced hemorrhage and brain injury by free radical spin trapping after embolic focal cerebral ischemia in rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cyclic N-Oxides; Drug Therapy, Combination; Free Radicals; Hypertension; Intracranial Embolism; Male; Nitrogen Oxides; Plasminogen Activators; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Spin Trapping; Tissue Plasminogen Activator

2000
Effect of alpha-phenyl-N-tert-butyl nitrone (PBN) on fetal cerebral energy metabolism during intrauterine ischemia and reperfusion in rats.
    Pediatric research, 2000, Volume: 47, Issue:4 Pt 1

    Topics: Animals; Brain; Cyclic N-Oxides; Energy Metabolism; Female; Nitrogen Oxides; Oxygen; Pregnancy; Rats; Rats, Wistar; Reperfusion Injury; Uterus

2000
Neurological impairment in rats after transient middle cerebral artery occlusion: a comparative study under various treatment paradigms.
    Brain research, 2000, Apr-28, Volume: 863, Issue:1-2

    Topics: Animals; Arterial Occlusive Diseases; Blood Glucose; Blood Pressure; Cerebral Cortex; Cyclic N-Oxides; Hematocrit; Hemoglobins; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Motor Activity; Neurologic Examination; Neuroprotective Agents; Nitrogen Oxides; Postural Balance; Psychomotor Performance; Rats; Recovery of Function; Reperfusion Injury; Time Factors

2000
Posthypoxic reoxygenation-induced neurotoxicity prevented by free radical scavenger and NMDA/non-NMDA antagonist in tandem as revealed by dynamic changes in glucose metabolism with positron autoradiography.
    Experimental neurology, 2000, Volume: 164, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Autoradiography; Cell Hypoxia; Cell Survival; Coloring Agents; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fluorodeoxyglucose F18; Free Radical Scavengers; Glucose; Glycolysis; Hypoxia, Brain; In Vitro Techniques; Lactic Acid; Male; Neurons; Neuroprotective Agents; Nitrogen Oxides; Oxazines; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Xanthenes

2000
Detection of free radicals in ischemic and reperfused canine gracilis muscle flaps by use of spin-trapping electron paramagnetic resonance spectroscopy.
    American journal of veterinary research, 2001, Volume: 62, Issue:3

    Topics: Animals; Biopsy; Cyclic N-Oxides; Dogs; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Histocytochemistry; Ischemia; Muscle, Skeletal; Nitrogen Oxides; Reperfusion Injury; Spin Trapping; Surgical Flaps

2001
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
    The American journal of pathology, 2001, Volume: 159, Issue:3

    Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Hypoxia; Immunohistochemistry; Ischemia; Nitrogen Oxides; Oxidative Stress; Oxygen; Placenta; Pregnancy; Pregnancy Complications; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tissue Distribution; Tyrosine

2001
Effects of adenosine pretreatment on detection of free radicals in ischemic and reperfused canine gracilis muscle flaps by use of spin-trapping electron paramagnetic resonance spectroscopy.
    American journal of veterinary research, 2002, Volume: 63, Issue:2

    Topics: Adenosine; Animals; Cyclic N-Oxides; Dogs; Electron Spin Resonance Spectroscopy; Free Radicals; Ischemia; Muscle, Skeletal; Nitrogen Oxides; Reperfusion Injury; Spin Trapping; Surgical Flaps

2002
Ischemia-reperfusion induced acute renal failure in the rat is ameliorated by the spin-trapping agent alpha-phenyl-N-tert-butyl nitrone (PBN).
    Renal failure, 1992, Volume: 14, Issue:4

    Topics: Acute Kidney Injury; Analysis of Variance; Animals; Body Weight; Cyclic N-Oxides; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Nitrogen Oxides; Rats; Rats, Wistar; Reperfusion Injury

1992
Relationship between free radical production and lipid peroxidation during ischemia-reperfusion injury in the rat brain.
    Brain research, 1991, Jul-19, Volume: 554, Issue:1-2

    Topics: Animals; Blood Pressure; Blood Volume; Carbon Dioxide; Cerebral Cortex; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Heart Rate; Ischemic Attack, Transient; Lipid Peroxidation; Male; Nitrogen Oxides; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Reference Values; Reperfusion Injury; Spin Labels

1991
Protection against oxidative damage to CNS by alpha-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: a novel series of nonlipid free radical scavengers.
    Journal of molecular neuroscience : MN, 1991, Volume: 3, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Cyclic N-Oxides; Free Radicals; Gerbillinae; Glutamate-Ammonia Ligase; Ischemic Attack, Transient; Nitrogen Oxides; Oxidation-Reduction; Oxygen; Reperfusion Injury; Salicylates; Salicylic Acid; Spin Labels

1991
The free radical trapping agent N-tert.-butyl-alpha-phenylnitrone (PBN) attenuates cerebral ischaemic injury in gerbils.
    Free radical research communications, 1991, Volume: 15, Issue:3

    Topics: Animals; Brain Ischemia; Cyclic N-Oxides; Free Radicals; Gerbillinae; Motor Activity; Nitrogen Oxides; Reperfusion Injury; Spin Labels; Temperature

1991
Evidence of in vivo free radical generation by spin trapping with alpha-phenyl N-tert-butyl nitrone during ischemia/reperfusion in rabbit kidneys.
    Free radical research communications, 1990, Volume: 9, Issue:3-6

    Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Kidney; Nitrogen Oxides; Rabbits; Reperfusion Injury; Spin Labels

1990
Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-alpha-phenylnitrone (PBN).
    Neuroscience letters, 1990, Aug-24, Volume: 116, Issue:3

    Topics: Animals; Brain Ischemia; Cyclic N-Oxides; Gerbillinae; Hippocampus; Male; Motor Activity; Nitrogen Oxides; Reperfusion Injury; Spin Labels

1990