phenyl-n-tert-butylnitrone and Pregnancy

phenyl-n-tert-butylnitrone has been researched along with Pregnancy in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's6 (25.00)18.2507
2000's11 (45.83)29.6817
2010's5 (20.83)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Bulić-Jakuš, F; Himelreich-Perić, M; Ježek, D; Jurić-Lekić, G; Katušić-Bojanac, A; Krasić, J; Majić, Ž; Marić, A; Šerman, L; Sinčić, N; Sobočan, N1
Jablonski, SA; Vorhees, CV; Williams, MT1
Cheng, J; Miller, L; Shapiro, AM; Wells, PG1
Shapiro, AM; Siu, MT; Wells, PG; Wiley, MJ1
Miller-Pinsler, L; Pinto, DJ; Wells, PG1
Cai, Z; Chen, RF; Fan, LW; Lin, RC; Mitchell, HJ; Rhodes, PG; Simpson, KL1
Chen, YH; Ji, YL; Meng, XH; Wang, H; Wang, Z; Xu, DX; Xu, ZM; Zhang, C; Zhang, ZH; Zhao, M1
Araki, T; Asakura, H; Koshino, T; Nakai, A; Oya, A; Taniuchi, Y1
Araki, T; Koshino, T; Nakai, A; Taniuchi, Y1
Chen, YH; Sun, MF; Wang, H; Wang, JP; Wei, LZ; Wei, W; Xu, DX1
Chen, YH; Wang, H; Wei, W; Xu, DX; Zhao, L1
Ji, YL; Li, XY; Wang, H; Wang, SF; Xu, DX; Zhang, C; Zhao, L1
Cai, Z; Fan, LW; Mitchell, HJ; Rhodes, PG; Tien, LT1
Cheng, Y; Sun, AY1
Fisher, JE; Potturi, RB; Resnick, E; Zimmerman, EF1
Jain, S; Kopergaonkar, S; Laloraya, M; Pradeep Kumar, G; Thomas, M1
Arikawa, J; Kasai, N; Kon, Y; Kuwabara, M; Miyoshi, I; Watanabe, T; Yamashita, T; Yamazaki, H1
Delivoria-Papadopoulos, M; Maulik, D; Mishra, OP; Numagami, Y; Ohnishi, ST1
Parman, T; Wells, PG; Wiley, MJ1
Araki, T; Asakura, H; Koshino, T; Nakai, A; Siesjö, BK; Taniuchi, Y1
Araki, T; Asakura, H; Koshino, T; Nakai, A; Oya, A; Taniuchi, Y; Yokota, A1
Burton, GJ; Hung, TH; Skepper, JN1
Aguirre, F; Capani, F; De Paoli, T; Facorro, G; Farach, H; Hager, A; Loidl, CF; Pecci-Saavedra, J; Piehl, L1
Ali, S; Molinari, LM; Wells, PG; Wong, ST; Zubovits, JT1

Other Studies

24 other study(ies) available for phenyl-n-tert-butylnitrone and Pregnancy

ArticleYear
Extended Prophylactic Effect of N-tert-Butyl-α-phenylnitron against Oxidative/Nitrosative Damage Caused by the DNA-Hypomethylating Drug 5-Azacytidine in the Rat Placenta.
    International journal of molecular sciences, 2022, Jan-06, Volume: 23, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azacitidine; Biomarkers; Cell Proliferation; Cyclic N-Oxides; DNA Methylation; Female; Nitrosation; Organ Size; Oxidative Stress; Placenta; Pregnancy; Proliferating Cell Nuclear Antigen; Rats, Inbred F344; Tyrosine

2022
Learning and memory effects of neonatal methamphetamine exposure in rats: Role of reactive oxygen species and age at assessment.
    Synapse (New York, N.Y.), 2017, Volume: 71, Issue:11

    Topics: Animals; Animals, Newborn; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Female; Freezing Reaction, Cataleptic; Learning; Learning Disabilities; Male; Memory; Methamphetamine; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species

2017
The free radical spin trapping agent phenylbutylnitrone reduces fetal brain DNA oxidation and postnatal cognitive deficits caused by in utero exposure to a non-structurally teratogenic dose of ethanol: a role for oxidative stress.
    Free radical biology & medicine, 2013, Volume: 60

    Topics: Animals; Brain; Cyclic N-Oxides; DNA; DNA Damage; Ethanol; Female; Fetus; Free Radicals; Learning; Male; Mice; Oxidation-Reduction; Pregnancy; Reactive Oxygen Species; Spin Trapping

2013
A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol.
    Toxicology and applied pharmacology, 2013, Dec-15, Volume: 273, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehyde Oxidoreductases; Animals; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Free Radicals; Glutathione; Male; Methanol; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Oxidative Stress; Pregnancy; Reactive Oxygen Species; Tandem Mass Spectrometry; Teratogens

2013
Oxidative DNA damage in the in utero initiation of postnatal neurodevelopmental deficits by normal fetal and ethanol-enhanced oxidative stress in oxoguanine glycosylase 1 knockout mice.
    Free radical biology & medicine, 2015, Volume: 78

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Avoidance Learning; Brain; Central Nervous System Depressants; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; DNA Glycosylases; DNA Repair; Embryo, Mammalian; Ethanol; Female; Fetus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Reactive Oxygen Species

2015
alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced brain injury and improves neurological reflexes and early sensorimotor behavioral performance in juvenile rats.
    Journal of neuroscience research, 2008, Volume: 86, Issue:16

    Topics: Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Central Nervous System Bacterial Infections; Cyclic N-Oxides; Disease Models, Animal; Female; Gait Disorders, Neurologic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Leukomalacia, Periventricular; Lipopolysaccharides; Male; Movement Disorders; Myelin Basic Protein; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Pregnancy; Rats; Rats, Sprague-Dawley; Recovery of Function; Reflex

2008
Cadmium-induced teratogenicity: association with ROS-mediated endoplasmic reticulum stress in placenta.
    Toxicology and applied pharmacology, 2012, Mar-01, Volume: 259, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Cadmium; Cyclic N-Oxides; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Fetal Development; Free Radical Scavengers; Histocytochemistry; Male; Maternal Exposure; Mice; Mice, Inbred ICR; Placenta; Pregnancy; Random Allocation; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA; Transcription Factor CHOP; Unfolded Protein Response

2012
Windows of therapeutic opportunity on fetal growth retardation induced by transient intrauterine ischemia in rats.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2002, Volume: 69, Issue:6

    Topics: Animals; Cyclic N-Oxides; Dizocilpine Maleate; Female; Fetal Growth Retardation; Fetal Hypoxia; Ischemia; Neuroprotective Agents; Nifedipine; Nitrogen Oxides; Pregnancy; Random Allocation; Rats; Rats, Wistar; Tacrolimus

2002
Maternal treatment with alpha-phenyl-N-tert-butylnitrone attenuates secondary mitochondrial dysfunction after transient intrauterine asphyxia in the fetal rat brain.
    Gynecologic and obstetric investigation, 2003, Volume: 55, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arteries; Asphyxia; Brain Ischemia; Constriction; Cyclic N-Oxides; Female; Fetal Diseases; Maternal-Fetal Exchange; Mitochondrial Diseases; Nitrogen Oxides; Oxygen Consumption; Pregnancy; Rats; Rats, Wistar; Uterus

2003
Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta.
    Toxicology, 2005, Aug-01, Volume: 211, Issue:3

    Topics: Acetylcysteine; Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Cyclic N-Oxides; Cytochrome P-450 CYP3A; Down-Regulation; Female; Free Radical Scavengers; Glutathione; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Nitrogen Oxides; Oxidoreductases, N-Demethylating; Placenta; Pregnancy; Pregnane X Receptor; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiobarbituric Acid Reactive Substances

2005
Reactive oxygen species are involved in lipopolysaccharide-induced intrauterine growth restriction and skeletal development retardation in mice.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:6

    Topics: Animals; Bone Development; Crown-Rump Length; Cyclic N-Oxides; Dose-Response Relationship, Drug; Female; Fetal Death; Fetal Growth Retardation; Fetal Weight; Free Radical Scavengers; Gestational Age; Glutathione; Lipid Peroxidation; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; Osteogenesis; Pregnancy; Reactive Oxygen Species; Tail

2006
Maternally administered lipopolysaccharide (LPS) upregulates the expression of heme oxygenase-1 in fetal liver: the role of reactive oxygen species.
    Toxicology letters, 2008, Feb-15, Volume: 176, Issue:3

    Topics: Amniotic Fluid; Animals; Cyclic N-Oxides; Female; Gestational Age; Glutathione; Heme Oxygenase-1; Injections, Intraperitoneal; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Maternal Exposure; Mice; Mice, Inbred ICR; Nitrates; Nitrites; Pregnancy; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Up-Regulation

2008
Alpha-phenyl-n-tert-butyl-nitrone ameliorates hippocampal injury and improves learning and memory in juvenile rats following neonatal exposure to lipopolysaccharide.
    The European journal of neuroscience, 2008, Volume: 27, Issue:6

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Cyclic N-Oxides; Female; Hippocampus; Learning; Lipopolysaccharides; Male; Memory; Motor Activity; Neuroprotective Agents; Pregnancy; Rats; Rats, Sprague-Dawley

2008
Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons.
    Neurochemical research, 1994, Volume: 19, Issue:12

    Topics: Allopurinol; Animals; Calpain; Catalase; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic N-Oxides; Enzyme Activation; Female; Free Radical Scavengers; Free Radicals; Glycoproteins; Kainic Acid; Nitrogen Oxides; Oxidation-Reduction; Pregnancy; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Xanthine Oxidase

1994
Role of oxygen free radicals in cocaine-induced vascular disruption in mice.
    Teratology, 1994, Volume: 49, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Aorta; Blood Vessels; Cocaine; Cyclic N-Oxides; Female; Fetal Diseases; Fetal Heart; Gestational Age; Hemorrhage; Lipid Peroxidation; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Nervous System; Nervous System Malformations; Neural Tube Defects; Nitrogen Oxides; Pregnancy; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines; Vasodilation; Yolk Sac

1994
Estrogen surge: a regulatory switch for superoxide radical generation at implantation.
    Biochemistry and molecular biology international, 1996, Volume: 39, Issue:5

    Topics: Animals; Cyclic N-Oxides; Embryo Implantation; Estradiol; Estrogens; Female; Mice; Nitrogen Oxides; Ovariectomy; Pregnancy; Progesterone; Spectrophotometry; Superoxide Dismutase; Superoxides; Uterus

1996
Progressive effect of alpha-phenyl-N-tert-butyl nitrone (PBN) on rat embryo development in vitro.
    Free radical biology & medicine, 1997, Volume: 23, Issue:7

    Topics: Animals; Blastocyst; Culture Techniques; Cyclic N-Oxides; Embryonic and Fetal Development; Female; Free Radicals; Nitrogen Oxides; Pregnancy; Rats; Reactive Oxygen Species; Spin Labels; Superoxide Dismutase

1997
Direct measurement of oxygen free radicals during in utero hypoxia in the fetal guinea pig brain.
    Brain research, 1998, Jul-06, Volume: 798, Issue:1-2

    Topics: Animals; Brain; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Female; Fetus; Guinea Pigs; Hypoxia; Lipid Peroxides; Nitrogen Oxides; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase

1998
Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity.
    Nature medicine, 1999, Volume: 5, Issue:5

    Topics: Animals; Cyclic N-Oxides; DNA Damage; Drug Resistance; Embryo Loss; Embryo, Mammalian; Female; Free Radical Scavengers; Free Radicals; Hernia, Umbilical; Hypnotics and Sedatives; Limb Deformities, Congenital; Mice; Nitrogen Oxides; Oxidation-Reduction; Pregnancy; Rabbits; Species Specificity; Teratogens; Thalidomide

1999
Effect of alpha-phenyl-N-tert-butyl nitrone (PBN) on fetal cerebral energy metabolism during intrauterine ischemia and reperfusion in rats.
    Pediatric research, 2000, Volume: 47, Issue:4 Pt 1

    Topics: Animals; Brain; Cyclic N-Oxides; Energy Metabolism; Female; Nitrogen Oxides; Oxygen; Pregnancy; Rats; Rats, Wistar; Reperfusion Injury; Uterus

2000
Developmental changes in tolerance to transient intrauterine ischemia in rat cerebral mitochondria.
    American journal of obstetrics and gynecology, 2001, Volume: 184, Issue:4

    Topics: Adenosine Diphosphate; Animals; Arteries; Brain; Brain Ischemia; Cyclic N-Oxides; Female; Fetal Diseases; Gestational Age; Ischemia; Mitochondria; Nitrogen Oxides; Oxygen Consumption; Pregnancy; Rats; Rats, Wistar; Spin Labels; Uterus

2001
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
    The American journal of pathology, 2001, Volume: 159, Issue:3

    Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Hypoxia; Immunohistochemistry; Ischemia; Nitrogen Oxides; Oxidative Stress; Oxygen; Placenta; Pregnancy; Pregnancy Complications; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tissue Distribution; Tyrosine

2001
Changes in reactive oxygen species (ROS) production in rat brain during global perinatal asphyxia: an ESR study.
    Brain research, 2001, Sep-28, Volume: 914, Issue:1-2

    Topics: Animals; Asphyxia Neonatorum; Brain Chemistry; Chelating Agents; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Fetus; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Neostriatum; Neuroprotective Agents; Nitrogen Oxides; Pentetic Acid; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Survival Rate; Time Factors

2001
Modulation of phenytoin teratogenicity and embryonic covalent binding by acetylsalicylic acid, caffeic acid, and alpha-phenyl-N-t-butylnitrone: implications for bioactivation by prostaglandin synthetase.
    Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Biotransformation; Caffeic Acids; Cinnamates; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Female; Fetal Resorption; Free Radicals; Mice; Nitrogen Oxides; Phenytoin; Pregnancy; Prostaglandin-Endoperoxide Synthases

1989