phenyl-n-tert-butylnitrone and Nerve Degeneration

phenyl-n-tert-butylnitrone has been researched along with Nerve Degeneration in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (35.29)18.2507
2000's10 (58.82)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, Z; Fan, LW; Mitchell, HJ; Rhodes, PG; Tien, LT1
LaManna, JC; Puchowicz, MA; Sun, X; Xu, K1
Christen, S; Gergely, S; Leib, SL; Lykkesfeldt, J; Schaper, M; Täuber, MG; Zbären, J1
Bickford, PC; Kaufmann, JA; Taglialatela, G1
Bifrare, YD; Gianinazzi, C; Imboden, H; Leib, SL; Täuber, MG1
Horner, PJ; Milatovic, D; Montine, KS; Montine, TJ; Zaja-Milatovic, S1
Kruck, TP; Lukiw, WJ; Percy, ME1
Chen, M; Cheng, Y; Sun, AY; Wixom, P1
Colado, MI; Green, AR1
Brundin, P; Grasbon-Frodl, EM; Nakao, N; Widner, H1
Colado, MI; Green, AR; Misra, A; Murray, TK; Williams, JL1
Beal, MF; Fallon, J; Hyman, BT; Matthews, RT1
Brundin, P; Nakao, N1
Barbay, S; Barth, TM; Hoane, MR1
Hossmann, KA; Krep, H; Oschlies, U; Schwindt, W1
Dettbarn, WD; Gupta, RC; Milatovic, D; Zivin, M1
Camarero, J; Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; Sanchez, V1

Other Studies

17 other study(ies) available for phenyl-n-tert-butylnitrone and Nerve Degeneration

ArticleYear
Interleukin-1beta-induced brain injury in the neonatal rat can be ameliorated by alpha-phenyl-n-tert-butyl-nitrone.
    Experimental neurology, 2009, Volume: 220, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Cell Death; Cyclic N-Oxides; Cytoprotection; Disease Models, Animal; Encephalitis; Female; Gliosis; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Male; Microglia; Nerve Degeneration; Neuroprotective Agents; Oligodendroglia; Oxidative Stress; Rats

2009
Decreased brainstem function following cardiac arrest and resuscitation in aged rat.
    Brain research, 2010, Apr-30, Volume: 1328

    Topics: Aging; Animals; Antioxidants; Brain Stem; Brain Stem Infarctions; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Heart Arrest; Hippocampus; Male; Mitochondria; Nerve Degeneration; Oxidative Stress; Rats; Rats, Inbred F344; Recovery of Function; Reperfusion Injury; Respiratory Insufficiency; Resuscitation; Treatment Outcome

2010
Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis.
    Journal of neuropathology and experimental neurology, 2002, Volume: 61, Issue:7

    Topics: Alcohol Oxidoreductases; Aldehydes; Animals; Antioxidants; Cerebral Arteries; Cyclic N-Oxides; Cystine; Encephalitis; Female; Free Radical Scavengers; Glutamate-Ammonia Ligase; Lipid Peroxidation; Meningitis, Bacterial; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species; Streptococcus pneumoniae; Superoxide Dismutase

2002
Free radical-dependent changes in constitutive Nuclear factor kappa B in the aged hippocampus.
    Neuroreport, 2002, Oct-28, Volume: 13, Issue:15

    Topics: Active Transport, Cell Nucleus; Aging; Animals; Cell Nucleus; Cyclic N-Oxides; Free Radical Scavengers; Free Radicals; Hippocampus; Nerve Degeneration; Neuroprotective Agents; NF-kappa B; Nitrogen Oxides; Oxidative Stress; Rats; Rats, Inbred F344

2002
Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats.
    Hippocampus, 2003, Volume: 13, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Caspase 3; Caspases; Cell Death; Cyclic N-Oxides; Dentate Gyrus; Female; In Situ Nick-End Labeling; Meningitis, Pneumococcal; Necrosis; Nerve Degeneration; Neurons; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Streptococcus agalactiae; Streptococcus pneumoniae; Treatment Outcome

2003
Pharmacologic suppression of neuronal oxidative damage and dendritic degeneration following direct activation of glial innate immunity in mouse cerebrum.
    Journal of neurochemistry, 2003, Volume: 87, Issue:6

    Topics: Analysis of Variance; Animals; Biomarkers; Body Temperature; Cell Count; Cyclic N-Oxides; Dendrites; Dinoprostone; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Female; Free Radical Scavengers; Immunity, Innate; Immunohistochemistry; Injections, Intraventricular; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Degeneration; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Oxidation-Reduction; Peptides; Silver Staining; Telencephalon; Time Factors; Tocopherols

2003
Metal sulfate-mediated induction of pathogenic genes and repression by phenyl butyl nitrone and Feralex-G.
    Neuroreport, 2008, Jan-22, Volume: 19, Issue:2

    Topics: Antioxidants; Cell Line; Cyclic N-Oxides; Cyclooxygenase 2; Drug Synergism; Encephalitis; Gene Expression Regulation; Humans; Iron Chelating Agents; Metals; Monosaccharides; Nerve Degeneration; Neurons; Oxidative Stress; Phospholipases A2; Pyridones; Reactive Oxygen Species; RNA, Messenger; Sulfates; Transcriptional Activation

2008
Extracellular ATP may induce neuronal degeneration by a free-radical mechanism.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calpain; Cell Death; Cell Survival; Cyclic N-Oxides; Free Radical Scavengers; Free Radicals; Iron; L-Lactate Dehydrogenase; Lipid Peroxidation; Nerve Degeneration; Nitrogen Oxides; PC12 Cells; Pyrophosphatases; Rats; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase

1994
The spin trap reagent alpha-phenyl-N-tert-butyl nitrone prevents 'ecstasy'-induced neurodegeneration of 5-hydroxytryptamine neurones.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: Analysis of Variance; Animals; Binding, Competitive; Cerebral Cortex; Cyclic N-Oxides; Free Radicals; Hippocampus; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurons, Afferent; Nitrogen Oxides; Paroxetine; Rats; Serotonin; Serotonin Antagonists; Spin Labels

1995
Antioxidant treatment protects striatal neurons against excitotoxic insults.
    Neuroscience, 1996, Volume: 73, Issue:1

    Topics: Animals; Antioxidants; Cell Death; Cell Survival; Cells, Cultured; Cyclic N-Oxides; Dopamine and cAMP-Regulated Phosphoprotein 32; Female; Hypoglycemia; Immunohistochemistry; NADPH Dehydrogenase; Neostriatum; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitrogen Oxides; Phosphoproteins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Spin Labels; Stereotyped Behavior; Substantia Nigra

1996
The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine.
    Neuropharmacology, 1996, Volume: 35, Issue:11

    Topics: Animals; Body Temperature; Brain; Brain Chemistry; Cyclic N-Oxides; Fenfluramine; Hydroxyindoleacetic Acid; Male; Nerve Degeneration; Neurons; Nitrogen Oxides; p-Chloroamphetamine; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Spin Labels; Spin Trapping

1996
MPP+ produces progressive neuronal degeneration which is mediated by oxidative stress.
    Experimental neurology, 1997, Volume: 144, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Coenzymes; Cyclic N-Oxides; Dopamine Agents; Drug Combinations; Ions; Male; Nerve Degeneration; Niacinamide; Nitrogen Oxides; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spin Labels; Substantia Nigra; Time Factors; Ubiquinone

1997
Effects of alpha-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid.
    Neuroscience, 1997, Volume: 76, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Cell Survival; Cyclic N-Oxides; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Female; Functional Laterality; Immunohistochemistry; Motor Neurons; Movement; Neostriatum; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitro Compounds; Nitrogen Oxides; Phosphoproteins; Propionates; Quinolinic Acids; Rats; Rats, Sprague-Dawley; Stereotyped Behavior

1997
Large cortical lesions produce enduring forelimb placing deficits in un-treated rats and treatment with NMDA antagonists or anti-oxidant drugs induces behavioral recovery.
    Brain research bulletin, 2000, Sep-15, Volume: 53, Issue:2

    Topics: Animals; Antioxidants; Brain Injuries; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Forelimb; Lameness, Animal; Magnesium Chloride; Male; Motor Activity; Motor Cortex; Nerve Degeneration; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Touch; Vibrissae

2000
Electron microscopic investigation of rat brain after brief cardiac arrest.
    Acta neuropathologica, 2001, Volume: 101, Issue:2

    Topics: Animals; Brain; Brain Ischemia; Capillaries; Cardiovascular Physiological Phenomena; Cell Nucleus; Cell Size; Chromatin; Cyclic N-Oxides; Heart Arrest; Microscopy, Electron; Nerve Degeneration; Neuroglia; Neurons; Neuroprotective Agents; Nitrogen Oxides; Nuclear Envelope; Organelles; Rats

2001
Alterations in cytochrome c oxidase activity and energy metabolites in response to kainic acid-induced status epilepticus.
    Brain research, 2001, Aug-31, Volume: 912, Issue:1

    Topics: Adenosine Triphosphate; Amygdala; Animals; Antioxidants; Brain; Cerebral Cortex; Cyclic N-Oxides; Electron Transport Complex IV; Energy Metabolism; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurotoxins; Nitrogen Oxides; Oxidative Stress; Phosphocreatine; Rats; Reactive Oxygen Species; RNA, Messenger; Status Epilepticus; Vitamin E

2001
A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Animals; Chlormethiazole; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fever; Free Radicals; Hydroxybenzoates; Injections, Intraperitoneal; Male; Mice; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitrogen Oxides; Pyridines; Salicylic Acid

2001