phenyl-n-tert-butylnitrone and Disease Models, Animal

phenyl-n-tert-butylnitrone has been researched along with Disease Models, Animal in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.79)	18.7374
1990's	8 (14.29)	18.2507
2000's	33 (58.93)	29.6817
2010's	13 (23.21)	24.3611
2020's	1 (1.79)	2.80

Authors

Authors	Studies
Chamorro, B; Chioua, M; Diez-Iriepa, D; Fernández, I; García-Vieira, D; Gonzàlez-Nieto, D; Hadjipavlou-Litina, D; Iriepa, I; López-Muñoz, F; Marco-Contelles, J; Martínez-Murillo, R; Merás-Sáiz, B; Oset-Gasque, MJ	1
Jablonski, SA; Vorhees, CV; Williams, MT	1
Chen, F; Chen, SP; Liu, DQ; Mei, W; Rittner, H; Sun, J; Tian, YK; Ye, DW; Zhang, HX; Zhou, XR; Zhou, YQ	1
Candiotti, KA; Hao, S; Huang, W; Iida, T; Kanda, H; Levitt, RC; Liu, S; Lubarsky, DA; Yi, H	1
Cui, WG; Hu, P; Hu, ZY; Lu, Q; Ma, L; Mei, QY; Xu, DY; Zhao, Q; Zhao, X; Zhou, DS; Zhou, WH	1
Hu, ZY; Li, XL; Liu, X; Ma, Q; Wang, C; Zhao, X; Zhou, DS; Zhou, WH	1
Chen, LH; Cheng, RX; Gao, YJ; Huang, Y; Liu, T; Liu, TT; Wang, S; Wang, XL; Zhou, FM; Zhou, Y	1
Cai, Z; Chen, RF; Fan, LW; Lin, RC; Mitchell, HJ; Rhodes, PG; Simpson, KL	1
Ancha, HR; Harty, RF; Kurella, RR; Lightfoot, S; McKimmey, CC	1
Chung, JM; Chung, K; Kim, HY	1
Bacskai, BJ; Borrelli, LA; Garcia-Alloza, M; Hyman, BT	1
Ikeda, M; Kobayashi, C; Saito, K	1
Farooqui, AA; Ong, WY; Tang, N; Yeo, JF	1
Aschner, M; Gupta, RC; Milatovic, D; Zaja-Milatovic, S	1
Cai, Z; Fan, LW; Mitchell, HJ; Rhodes, PG; Tien, LT	1
LaManna, JC; Puchowicz, MA; Sun, X; Xu, K	1
Condon, D; Dhiman, M; Garg, NJ; Guan, Z; Gupta, S; Lui, C; Wen, JJ	1
Chung, JM; Chung, K; Kim, HK; Kim, HY; Lee, KY; Wang, J; Yowtak, J	1
Curtis, KM; Jayakumar, AR; Moriyama, M; Norenberg, MD; Panickar, KS; Tong, XY	1
Altomare, C; de Candia, M; Fiorella, F; Labandeira-García, JL; Méndez-Álvarez, E; Rodríguez-Pallares, J; Sánchez-Iglesias, S; Soto-Otero, R; Varlamov, AV; Voskressensky, LG; Zaytsev, VP; Zubkov, FI	1
Ahn, HN; Chan, PH; Chang, M; Narasimhan, P; Song, YS; Yang, J	1
Alvarado, M; Biegon, A; Budinger, TF; Floyd, RA; Grossman, R; Hensley, K; Kotake, Y; Ono, M; West, MS	1
Dettbarn, WD; Gupta, RC; Milatovic, D	1
Kotake, Y; Moore, DR; Sang, H; Tabatabaie, T; Vasquez-Walden, A	1
Bacskai, BJ; Hyman, BT; Kajdasz, ST; McLellan, ME	1
Anderson, RE; Kotake, Y; LaVail, MM; Ranchon, I	1
Keilhoff, G; Krug, M; Rauca, C; Wiswedel, I; Zerbe, R	1
Chung, JM; Chung, K; Coggeshall, RE; Kim, HK; Park, SK; Taglialatela, G; Zhou, JL	1
Fairfax, DF; Gupta, SK; Henry, P; Khan, RF; Mishra, RK; N-Marandi, S; Rogoza, RM	1
Medvedev, OS; Povarova, OV; Timoshin, AA	1
Brezová, V; Dobrota, D; Horecký, J; Kasparová, S; Liptaj, T; Mlynárik, V; Ulicná, O; Valko, M; Vancová, O	1
Griffith, JW; Peterson, SL; Purvis, RS	1
Clausen, F; Hillered, L; Lewén, A; Marklund, N; McArthur, DL; Olsson, Y	1
Jeong, SM; Kim, JH; Kim, KW; Yu, YS	1
Datta, PK; Lianos, EA; Reddy, S; Sharma, M	1
de Novellis, V; Ferraraccio, F; Fuccio, C; Giordano, C; Luongo, L; Maione, S; Palazzo, E; Rossi, F; Roth, KA; Siniscalco, D	1
Chung, JM; Chung, K; Kim, HK; Kim, JH; Lee, I	1
Doblas, S; Floyd, RA; Gordon, B; Kosanke, S; Kshirsagar, P; Oblander, J; Pye, Q; Saunders, D; Towner, RA	1
Burhop, K; Deby, C; Defraigne, JO; Detry, O; Franssen, C; Lamy, M; Meurisse, M; Philippart, C; Pincemail, J	1
Berliner, LJ; Borzone, G; Clanton, TL; Hartell, MG	1
Farooque, M; Hillered, L; Olsson, Y	1
Allix, M; Boulu, RG; Margaill, I; Mésenge, C; Plotkine, M; Verrecchia, C	1
Iwai, T; Nakashima, M; Niwa, M; Uematsu, T	1
Maines, MD; Panahian, N; Raju, VS	1
Li, Q; Shuaib, A; Yang, Y	1
Hablützel, M; Leib, SL; Loeffler, JM; Ringer, R; Täuber, MG	1
Chapman, DF; Lapchak, PA; Zivin, JA	1
Kotake, Y	1
Fatzer, R; Jungi, TW; Leib, SL; Remer, KA; Täuber, MG	1
Banic, S; Bifrare, YD; Christen, S; Leib, SL; Lykkesfeldt, J; Schaper, M; Siegenthaler, C; Täuber, MG	1
Aguirre, F; Capani, F; De Paoli, T; Facorro, G; Farach, H; Hager, A; Loidl, CF; Pecci-Saavedra, J; Piehl, L	1
Csiszar, K; He, QP; Li, PA; Nakamura, L	1
Collins, LV; Sakiniene, E	1
Clerici, WJ; Jones, RO; Tuncel, U	1
Bobadilla, N; Pedraza-Chaverri, J; Tapia, E	1
Fujita, Y; Imaizumi, S; Suzuki, J; Tominaga, T; Uenohara, H; Yoshimoto, T	1

Reviews

1 review(s) available for phenyl-n-tert-butylnitrone and Disease Models, Animal

Article	Year
Pharmacologic properties of phenyl N-tert-butylnitrone. Antioxidants & redox signaling, 1999,Winter, Volume: 1, Issue:4 Topics: Aging; Animals; Cyclic N-Oxides; Cytokines; Disease Models, Animal; Humans; In Vitro Techniques; Molecular Structure; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitrogen Oxides; Reperfusion Injury; Spin Trapping	1999

Other Studies

55 other study(ies) available for phenyl-n-tert-butylnitrone and Disease Models, Animal

Article	Year
Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models. Scientific reports, 2020, 08-25, Volume: 10, Issue:1 Topics: Animals; Apoptosis; Brain Ischemia; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Glucose; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Neuroblastoma; Neurons; Neuroprotection; Neuroprotective Agents; Nitrogen Oxides; Oligomycins; Oxygen; Rotenone	2020
Learning and memory effects of neonatal methamphetamine exposure in rats: Role of reactive oxygen species and age at assessment. Synapse (New York, N.Y.), 2017, Volume: 71, Issue:11 Topics: Animals; Animals, Newborn; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Female; Freezing Reaction, Cataleptic; Learning; Learning Disabilities; Male; Memory; Methamphetamine; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species	2017
Reactive oxygen species scavengers ameliorate mechanical allodynia in a rat model of cancer-induced bone pain. Redox biology, 2018, Volume: 14 Topics: Analgesics; Animals; Bone and Bones; Cancer Pain; Cyclic N-Oxides; Disease Models, Animal; Female; Free Radical Scavengers; Hyperalgesia; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels	2018
Inhibition of Mitochondrial Fission Protein Reduced Mechanical Allodynia and Suppressed Spinal Mitochondrial Superoxide Induced by Perineural Human Immunodeficiency Virus gp120 in Rats. Anesthesia and analgesia, 2016, Volume: 122, Issue:1 Topics: Analgesics; Animals; Cyclic N-Oxides; Disease Models, Animal; Dynamins; Free Radical Scavengers; HIV Envelope Protein gp120; HIV Infections; Hyperalgesia; Injections, Spinal; Male; Mitochondria; Mitochondrial Dynamics; Oligonucleotides, Antisense; Pain Threshold; Posterior Horn Cells; Quinazolinones; Rats, Sprague-Dawley; Recombinant Proteins; Sciatica; Superoxides; Time Factors	2016
Secoisolariciresinol diglycoside, a flaxseed lignan, exerts analgesic effects in a mouse model of type 1 diabetes: Engagement of antioxidant mechanism. European journal of pharmacology, 2015, Nov-15, Volume: 767 Topics: Analgesics; Animals; Antioxidants; Butylene Glycols; Cyclic N-Oxides; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Flax; Glycosides; Hyperalgesia; Lignans; Male; Mice; Neuralgia; Sciatic Nerve; Spinal Cord; tert-Butylhydroperoxide	2015
Antinociceptive effects of fisetin against diabetic neuropathic pain in mice: Engagement of antioxidant mechanisms and spinal GABAA receptors. Pharmacological research, 2015, Volume: 102 Topics: Analgesics; Animals; Antioxidants; Bicuculline; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Flavonoids; Flavonols; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Oxidative Stress; Reactive Oxygen Species; Receptors, GABA-A; Spinal Cord; Streptozocin	2015
Antioxidants Attenuate Acute and Chronic Itch: Peripheral and Central Mechanisms of Oxidative Stress in Pruritus. Neuroscience bulletin, 2017, Volume: 33, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Transformed; Central Nervous System; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Male; Malondialdehyde; Mice; Oxidative Stress; p-Methoxy-N-methylphenethylamine; Peripheral Nerves; Pruritus; Reactive Oxygen Species; Skin; Superoxide Dismutase; Time Factors	2017
alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced brain injury and improves neurological reflexes and early sensorimotor behavioral performance in juvenile rats. Journal of neuroscience research, 2008, Volume: 86, Issue:16 Topics: Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Central Nervous System Bacterial Infections; Cyclic N-Oxides; Disease Models, Animal; Female; Gait Disorders, Neurologic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Leukomalacia, Periventricular; Lipopolysaccharides; Male; Movement Disorders; Myelin Basic Protein; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Pregnancy; Rats; Rats, Sprague-Dawley; Recovery of Function; Reflex	2008
Luminal antioxidants enhance the effects of mesalamine in the treatment of chemically induced colitis in rats. Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:10 Topics: Animals; Antioxidants; Ascorbic Acid; Colitis; Cyclic N-Oxides; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Intestinal Mucosa; Male; Mesalamine; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Vitamin E	2008
Increased production of mitochondrial superoxide in the spinal cord induces pain behaviors in mice: the effect of mitochondrial electron transport complex inhibitors. Neuroscience letters, 2008, Dec-05, Volume: 447, Issue:1 Topics: Animals; Antimycin A; Behavior, Animal; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Pain; Pain Measurement; Pain Threshold; Spin Labels; Spinal Cord; Superoxides	2008
Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice. Neurobiology of aging, 2010, Volume: 31, Issue:12 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Chromans; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Ginkgo biloba; Mice; Mice, Transgenic; Oxidative Stress; Plant Extracts; Plaque, Amyloid; Presenilin-1; Time Factors	2010
Effect of radical scavenger N-tert-butyl-alpha-phenylnitrone on stroke in a rat model using a telemetric system. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2008, Volume: 11, Issue:4 Topics: Animals; Blood Pressure; Body Weight; Brain; Brain Ischemia; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Heart Rate; Motor Activity; Rats; Rats, Inbred SHR; Stroke	2008
Anti-allodynic effect of intracerebroventricularly administered antioxidant and free radical scavenger in a mouse model of orofacial pain. Journal of orofacial pain, 2009,Spring, Volume: 23, Issue:2 Topics: Animals; Antioxidants; Brain; Brain Stem; Bridged-Ring Compounds; Carrageenan; Cerebral Ventricles; Cyclic N-Oxides; Disease Models, Animal; Facial Pain; Free Radical Scavengers; Injections, Intraventricular; Male; Maxillary Nerve; Mice; Mice, Inbred BALB C; Norbornanes; Somatosensory Cortex; Sphingolipids; Sphingomyelin Phosphodiesterase; Stimulation, Chemical; Thalamus; Thiocarbamates; Thiones; Trigeminal Ganglion; Type C Phospholipases	2009
Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist. Toxicology and applied pharmacology, 2009, Oct-15, Volume: 240, Issue:2 Topics: Animals; Antioxidants; Biomarkers; Brain; Cholinesterase Inhibitors; Cyclic N-Oxides; Disease Models, Animal; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Isoflurophate; Lipid Peroxidation; Male; Memantine; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors; Vitamin A	2009
Interleukin-1beta-induced brain injury in the neonatal rat can be ameliorated by alpha-phenyl-n-tert-butyl-nitrone. Experimental neurology, 2009, Volume: 220, Issue:1 Topics: Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Cell Death; Cyclic N-Oxides; Cytoprotection; Disease Models, Animal; Encephalitis; Female; Gliosis; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Male; Microglia; Nerve Degeneration; Neuroprotective Agents; Oligodendroglia; Oxidative Stress; Rats	2009
Decreased brainstem function following cardiac arrest and resuscitation in aged rat. Brain research, 2010, Apr-30, Volume: 1328 Topics: Aging; Animals; Antioxidants; Brain Stem; Brain Stem Infarctions; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Heart Arrest; Hippocampus; Male; Mitochondria; Nerve Degeneration; Oxidative Stress; Rats; Rats, Inbred F344; Recovery of Function; Reperfusion Injury; Respiratory Insufficiency; Resuscitation; Treatment Outcome	2010
Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats. Journal of the American College of Cardiology, 2010, Jun-01, Volume: 55, Issue:22 Topics: Analysis of Variance; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Disease Progression; Heart Function Tests; Hemodynamics; Lipid Peroxidation; Mitochondria, Heart; Nitroimidazoles; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Trypanosoma cruzi	2010
Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release. Pain, 2011, Volume: 152, Issue:4 Topics: Analysis of Variance; Animals; Bicuculline; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Free Radical Scavengers; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Male; Mice; Neuralgia; Neurons; Reactive Oxygen Species; Spinal Cord; Spinal Nerves; tert-Butylhydroperoxide; Time Factors	2011
Na-K-Cl cotransporter-1 in the mechanism of cell swelling in cultured astrocytes after fluid percussion injury. Journal of neurochemistry, 2011, Volume: 117, Issue:3 Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Brain Edema; Brain Injuries; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; K Cl- Cotransporters; NG-Nitroarginine Methyl Ester; Percussion; Rats; RNA, Messenger; RNA, Small Interfering; Symporters; Time Factors; Transfection	2011
2-Benzazepine nitrones protect dopaminergic neurons against 6-hydroxydopamine-induced oxidative toxicity. Archiv der Pharmazie, 2012, Volume: 345, Issue:8 Topics: Animals; Benzazepines; Brain; Cell Count; Cells, Cultured; Cholinesterase Inhibitors; Cyclic N-Oxides; Disease Models, Animal; Dopaminergic Neurons; Inhibitory Concentration 50; Lipid Peroxidation; Mitochondria; Molecular Structure; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Oxidopamine; Parkinson Disease, Secondary; Primary Cell Culture; Protein Carbonylation; Structure-Activity Relationship	2012
Complement component 3 inhibition by an antioxidant is neuroprotective after cerebral ischemia and reperfusion in mice. Journal of neurochemistry, 2013, Volume: 124, Issue:4 Topics: Animals; Brain; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebral Cortex; Complement C3; Cyclic N-Oxides; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Glucose; Hypoxia; L-Lactate Dehydrogenase; Male; Mice; Mice, Transgenic; Nervous System Diseases; Neuroglia; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Up-Regulation	2013
Region-selective effects of neuroinflammation and antioxidant treatment on peripheral benzodiazepine receptors and NMDA receptors in the rat brain. Journal of neurochemistry, 2002, Volume: 82, Issue:4 Topics: Animals; Antioxidants; Autoradiography; Binding, Competitive; Brain; Cyclic N-Oxides; Disease Models, Animal; Dizocilpine Maleate; Drug Administration Routes; Encephalitis; Excitatory Amino Acid Antagonists; Isoquinolines; Lipopolysaccharides; Male; Microglia; Nitrogen Oxides; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tissue Distribution	2002
Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain. Brain research, 2002, Dec-13, Volume: 957, Issue:2 Topics: Adenosine Triphosphate; Animals; Brain; Cell Death; Citrulline; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Kainic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitrogen Oxides; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Status Epilepticus; Up-Regulation; Vitamin E	2002
Antioxidant amplifies antibiotic protection in the cecal ligation and puncture model of microbial sepsis through interleukin-10 production. Shock (Augusta, Ga.), 2003, Volume: 19, Issue:3 Topics: Animals; Anti-Bacterial Agents; Antioxidants; Bacterial Infections; Cecum; Cyclic N-Oxides; Disease Models, Animal; Drug Synergism; Interleukin-10; Interleukin-6; Kinetics; Lipopolysaccharides; Male; Nitrogen Oxides; Proline; Punctures; Rats; Rats, Wistar; Sepsis; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha	2003
In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Mar-15, Volume: 23, Issue:6 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Benzothiazoles; Cerebral Cortex; Cyclic N-Oxides; Disease Models, Animal; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Infrared Rays; Lasers; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Plaque, Amyloid; Reactive Oxygen Species; Thiazoles	2003
Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jul-09, Volume: 23, Issue:14 Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Cyclic N-Oxides; Disease Models, Animal; Electroretinography; Free Radical Scavengers; Genetic Predisposition to Disease; Light; Mutation; Nitrogen Oxides; Photic Stimulation; Photoperiod; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Rhodopsin; Sensory Thresholds; Treatment Outcome	2003
The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone. Brain research, 2004, May-29, Volume: 1009, Issue:1-2 Topics: alpha-Tocopherol; Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Gentisates; Hydroxybenzoates; Kindling, Neurologic; Male; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Superoxide Dismutase; Time Factors	2004
Reactive oxygen species (ROS) play an important role in a rat model of neuropathic pain. Pain, 2004, Volume: 111, Issue:1-2 Topics: Analgesics; Animals; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Ligation; Male; Neuralgia; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spinal Nerves	2004
Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia. Synapse (New York, N.Y.), 2004, Dec-01, Volume: 54, Issue:3 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Binding Sites; Corpus Striatum; Cyclic N-Oxides; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Dyskinesia, Drug-Induced; Electron Spin Resonance Spectroscopy; Haloperidol; Humans; Male; Mastication; Motor Activity; Movement Disorders; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Dopamine D2	2004
Protective effect of phenyl-t-butylnitrone in rats with focal cerebral ischemia. Bulletin of experimental biology and medicine, 2003, Volume: 136, Issue:6 Topics: Animals; Brain Chemistry; Brain Ischemia; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Free Radicals; Infarction, Middle Cerebral Artery; Kidney; Liver; Male; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Wistar; Spin Labels	2003
Study of the oxidative stress in a rat model of chronic brain hypoperfusion. Neurochemistry international, 2005, Volume: 46, Issue:8 Topics: Animals; Ascorbic Acid; Brain; Brain Ischemia; Chronic Disease; Creatine Kinase; Cyclic N-Oxides; Dementia; Disease Models, Animal; Energy Metabolism; Free Radicals; Hydroxyl Radical; Male; Mitochondria; Molecular Conformation; Nitrogen Oxides; Oxidative Phosphorylation; Oxidative Stress; Rats; Rats, Wistar; Spin Trapping	2005
Comparison of neuroprotective effects induced by alpha-phenyl-N-tert-butyl nitrone (PBN) and N-tert-butyl-alpha-(2 sulfophenyl) nitrone (S-PBN) in lithium-pilocarpine status epilepticus. Neurotoxicology, 2005, Volume: 26, Issue:6 Topics: Animals; Benzenesulfonates; Brain; Cyclic N-Oxides; Disease Models, Animal; Electroencephalography; Free Radical Scavengers; Lithium; Male; Neuroprotective Agents; Nitrogen Oxides; Pilocarpine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Status Epilepticus	2005
Correlation of hippocampal morphological changes and morris water maze performance after cortical contusion injury in rats. Neurosurgery, 2005, Volume: 57, Issue:1 Topics: Animals; Brain Concussion; Cell Count; Cerebral Cortex; Cyclic N-Oxides; Disease Models, Animal; Functional Laterality; Hippocampus; Immunohistochemistry; Male; Maze Learning; Microtubule-Associated Proteins; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Statistics as Topic; Time Factors; Trauma Severity Indices	2005
Delay of photoreceptor cell degeneration in rd mice by systemically administered phenyl-N-tert-butylnitrone. Korean journal of ophthalmology : KJO, 2005, Volume: 19, Issue:4 Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Enzyme Precursors; Female; Follow-Up Studies; Free Radical Scavengers; Injections, Intraperitoneal; Male; Mice; Neuroprotective Agents; Nitrogen Oxides; Photoreceptor Cells, Vertebrate; Pigment Epithelium of Eye; Retinal Degeneration	2005
Differential nephron HO-1 expression following glomerular epithelial cell injury. Nephron. Experimental nephrology, 2006, Volume: 103, Issue:4 Topics: Animals; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Heme Oxygenase-1; Kidney Glomerulus; Male; Nephrons; Nitrogen Oxides; Permeability; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Up-Regulation	2006
Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain. Pharmacological research, 2007, Volume: 55, Issue:2 Topics: Animals; Apoptosis; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Gene Expression; Hyperalgesia; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Pain; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sciatic Neuropathy; Spinal Cord	2007
The role of reactive oxygen species in capsaicin-induced mechanical hyperalgesia and in the activities of dorsal horn neurons. Pain, 2007, Dec-15, Volume: 133, Issue:1-3 Topics: Action Potentials; Analysis of Variance; Animals; Antioxidants; Behavior, Animal; Capsaicin; Cyclic N-Oxides; Disease Models, Animal; Drug Interactions; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Time Factors	2007
Phenyl-tert-butylnitrone induces tumor regression and decreases angiogenesis in a C6 rat glioma model. Free radical biology & medicine, 2008, Jan-01, Volume: 44, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Glioma; Immunohistochemistry; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Neoplasm Transplantation; Neovascularization, Pathologic; Neuroprotective Agents; Rats; Rats, Inbred F344; Software; Vascular Endothelial Growth Factor A; von Willebrand Factor	2008
Diaspirin crosslinked hemoglobin (DCLHb): absence of increased free radical generation following administration in a rabbit model of renal ischemia and reperfusion. Free radical biology & medicine, 1995, Volume: 19, Issue:1 Topics: Animals; Aspirin; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hemoglobins; Ischemia; Kidney; Kidney Cortex; Nitrogen Oxides; Rabbits; Reperfusion; Spin Labels; Vitamin E	1995
Detection of free radicals in blood by electron spin resonance in a model of respiratory failure in the rat. Free radical biology & medicine, 1994, Volume: 17, Issue:5 Topics: Animals; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Free Radicals; Male; Nitrogen Oxides; Oxygen; Rats; Rats, Sprague-Dawley; Respiratory Insufficiency; Spin Labels	1994
Pretreatment with alpha-phenyl-N-tert-butyl-nitrone (PBN) improves energy metabolism after spinal cord injury in rats. Journal of neurotrauma, 1997, Volume: 14, Issue:7 Topics: Animals; Cyclic N-Oxides; Disease Models, Animal; Energy Metabolism; Male; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors	1997
Protective effect of melatonin in a model of traumatic brain injury in mice. Journal of pineal research, 1998, Volume: 25, Issue:1 Topics: Animals; Antioxidants; Body Temperature; Brain Injuries; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Injections, Intraperitoneal; Male; Melatonin; Mice; Motor Activity; Nitrogen Oxides	1998
Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat. Free radical biology & medicine, 1999, Volume: 26, Issue:5-6 Topics: Animals; Antipyrine; Brain; Caudate Nucleus; Cerebral Infarction; Cyclic N-Oxides; Disease Models, Animal; Edaravone; Free Radical Scavengers; Free Radicals; Hippocampus; Ischemic Attack, Transient; Male; Nitroarginine; Nitrogen Oxides; Putamen; Rats; Rats, Inbred F344; Rats, Wistar; Reperfusion Injury; Spin Labels; Superior Colliculi	1999
Spin trap (N-t-butyl-alpha-phenylnitrone)-mediated suprainduction of heme oxygenase-1 in kidney ischemia/reperfusion model: role of the oxygenase in protection against oxidative injury. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Animals; Antibodies; Blotting, Northern; Blotting, Western; Cyclic N-Oxides; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Iron; Isoenzymes; Kidney; Lipid Peroxidation; Nitrogen Oxides; Oxidative Stress; Oxygenases; Rats; Reperfusion Injury; RNA, Messenger; Spin Trapping; Time Factors	1999
Neuroprotection by 2-h postischemia administration of two free radical scavengers, alpha-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia. Experimental neurology, 2000, Volume: 163, Issue:1 Topics: Animals; Benzenesulfonates; Brain; Brain Ischemia; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Neurologic Examination; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Wistar; Recovery of Function; Thrombin	2000
The free radical scavenger alpha-phenyl-tert-butyl nitrone aggravates hippocampal apoptosis and learning deficits in experimental pneumococcal meningitis. The Journal of infectious diseases, 2001, Jan-15, Volume: 183, Issue:2 Topics: Animals; Apoptosis; Cerebral Cortex; Cyclic N-Oxides; Dentate Gyrus; Disease Models, Animal; Free Radical Scavengers; Learning; Maze Learning; Meningitis, Pneumococcal; Neurons; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae	2001
Pharmacological effects of the spin trap agents N-t-butyl-phenylnitrone (PBN) and 2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPO) in a rabbit thromboembolic stroke model: combination studies with the thrombolytic tissue plasminogen activator. Stroke, 2001, Volume: 32, Issue:1 Topics: Animals; Cerebral Hemorrhage; Cyclic N-Oxides; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Infusions, Intravenous; Male; Neuroprotective Agents; Nitrogen Oxides; Rabbits; Reactive Oxygen Species; Reperfusion; Spin Labels; Stroke; Thromboembolism; Tissue Plasminogen Activator	2001
Nitric oxide is protective in listeric meningoencephalitis of rats. Infection and immunity, 2001, Volume: 69, Issue:6 Topics: Animals; Brain; Cyclic N-Oxides; Disease Models, Animal; Humans; Immunohistochemistry; Kinetics; Listeria monocytogenes; Listeriosis; Meningoencephalitis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Rats	2001
Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment. Free radical biology & medicine, 2001, Sep-15, Volume: 31, Issue:6 Topics: Acetylcysteine; Animals; Brain; Cerebrospinal Fluid; Cyclic N-Oxides; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione; Meningitis, Pneumococcal; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae	2001
Changes in reactive oxygen species (ROS) production in rat brain during global perinatal asphyxia: an ESR study. Brain research, 2001, Sep-28, Volume: 914, Issue:1-2 Topics: Animals; Asphyxia Neonatorum; Brain Chemistry; Chelating Agents; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Female; Fetus; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Neostriatum; Neuroprotective Agents; Nitrogen Oxides; Pentetic Acid; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Survival Rate; Time Factors	2001
Free radical spin trap alpha-phenyl-N-tert-butyl-nitron inhibits caspase-3 activation and reduces brain damage following a severe forebrain ischemic injury. Free radical biology & medicine, 2001, Nov-15, Volume: 31, Issue:10 Topics: Animals; Brain Ischemia; Caspase 3; Caspase Inhibitors; Cyclic N-Oxides; Disease Models, Animal; Male; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Wistar; Spin Trapping; Survival Rate	2001
Combined antibiotic and free radical trap treatment is effective at combating Staphylococcus-aureus-induced septic arthritis. Arthritis research, 2002, Volume: 4, Issue:3 Topics: Animals; Arthritis, Experimental; Arthritis, Infectious; Cloxacillin; Cyclic N-Oxides; Disease Models, Animal; Drug Therapy, Combination; Female; Free Radical Scavengers; Kidney; Mice; Mice, Inbred Strains; Nitrogen Oxides; Penicillins; Severity of Illness Index; Staphylococcus aureus; Synovitis; Treatment Outcome	2002
Differential ototoxicities induced by lead acetate and tetraethyl lead. Hearing research, 2002, Volume: 166, Issue:1-2 Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Threshold; Cochlea; Cochlear Microphonic Potentials; Cyclic N-Oxides; Disease Models, Animal; Evoked Potentials, Auditory; Free Radical Scavengers; Guinea Pigs; Lead; Lead Poisoning; Nitrogen Oxides; Organometallic Compounds; Tetraethyl Lead	2002
Ischemia-reperfusion induced acute renal failure in the rat is ameliorated by the spin-trapping agent alpha-phenyl-N-tert-butyl nitrone (PBN). Renal failure, 1992, Volume: 14, Issue:4 Topics: Acute Kidney Injury; Analysis of Variance; Animals; Body Weight; Cyclic N-Oxides; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Nitrogen Oxides; Rats; Rats, Wistar; Reperfusion Injury	1992
Initiation and propagation of lipid peroxidation in cerebral infarction models. Experimental studies. Neurological research, 1986, Volume: 8, Issue:4 Topics: Animals; Brain; Brain Ischemia; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Energy Metabolism; Free Radicals; Hypoxia, Brain; Lipid Peroxides; Luminescent Measurements; Male; Nitrogen Oxides; Rats; Rats, Inbred Strains	1986