phenyl biguanide has been researched along with Apnea in 7 studies
phenyl biguanide: RN given refers to parent cpd
phenyl biguanide : A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a phenyl group.
Apnea: A transient absence of spontaneous respiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prenatal nicotinic exposure (PNE) reportedly sensitizes bronchopulmonary C-fibers (PCFs) and prolongs PCF-mediated apnea in rat pups, contributing to the pathogenesis of sudden infant death syndrome." | 7.91 | Prolongation of bronchopulmonary C-fiber-mediated apnea by prenatal nicotinic exposure in rat pups: role of 5-HT ( Gao, X; Leng, S; Wallen, M; Xu, F; Zhao, L; Zhuang, J, 2019) |
| "Prenatal nicotinic exposure (PNE) reportedly sensitizes bronchopulmonary C-fibers (PCFs) and prolongs PCF-mediated apnea in rat pups, contributing to the pathogenesis of sudden infant death syndrome." | 3.91 | Prolongation of bronchopulmonary C-fiber-mediated apnea by prenatal nicotinic exposure in rat pups: role of 5-HT ( Gao, X; Leng, S; Wallen, M; Xu, F; Zhao, L; Zhuang, J, 2019) |
| " Since selective stimulation of PCFs by action on local 5-HT3 receptors could evoke an apnea, this current study addresses whether inhalation of ISO would facilitate the PCF 5-HT3 receptor-mediated apneic response and, if so, how." | 3.79 | Isoflurane inhibits bronchopulmonary C-fiber-mediated apneic response to phenylbiguanide by depressing 5-HT3 receptor function in anesthetized rats. ( Xu, F; Zhang, C; Zhang, Z; Zhuang, J, 2013) |
| " Intravenous (iv) injection of PDG (10 microg/kg), produced hypotension, bradycardia and apnea over a period of time." | 3.70 | Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats. ( Bagchi, S; Deshpande, SB, 2000) |
| " The response to bolus injection of PDG into the right atrium was qualitatively similar to the one seen in cats under anesthesia, consisting of bradycardia and apnea followed by rapid shallow breathing (RSB)." | 3.67 | The respiratory response to stimulation of juxta-pulmonary capillary receptors in the non-anesthetized cat. ( Ginzel, KH; Lucas, EA, 1985) |
| " Apnea followed by rapid shallow breathing was observed in most animals." | 3.66 | Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets. ( Gootman, N; Gootman, PM; Schleman, M, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, L | 1 |
| Gao, X | 1 |
| Zhuang, J | 2 |
| Wallen, M | 1 |
| Leng, S | 1 |
| Xu, F | 2 |
| Zhang, Z | 1 |
| Zhang, C | 1 |
| Bagchi, S | 2 |
| Deshpande, SB | 2 |
| Skofitsch, G | 1 |
| Saria, A | 1 |
| Lembeck, F | 1 |
| Rai, OP | 1 |
| Aryya, NC | 1 |
| Schleman, M | 1 |
| Gootman, N | 1 |
| Gootman, PM | 1 |
| Ginzel, KH | 1 |
| Lucas, EA | 1 |
7 other studies available for phenyl biguanide and Apnea
| Article | Year |
|---|---|
Prolongation of bronchopulmonary C-fiber-mediated apnea by prenatal nicotinic exposure in rat pups: role of 5-HT
Topics: Animals; Animals, Newborn; Apnea; Biguanides; Bronchoalveolar Lavage Fluid; Disease Models, Animal; | 2019 |
Isoflurane inhibits bronchopulmonary C-fiber-mediated apneic response to phenylbiguanide by depressing 5-HT3 receptor function in anesthetized rats.
Topics: Administration, Inhalation; Animals; Apnea; Biguanides; Isoflurane; Lung; Male; Membrane Potentials; | 2013 |
Phenyldiguanide activates cardiac receptors to produce responses by involving three different efferent pathways in anaesthetized rats.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Apnea; Biguanides; Blood Pressure; Bradyc | 2000 |
Phenyldiguanide and capsaicin stimulate functionally different populations of afferent C-fibers.
Topics: Animals; Apnea; Biguanides; Bradycardia; Capillary Permeability; Capsaicin; Hypotension; Male; Nerve | 1983 |
Pulmonary oedema produced by scorpion venom augments a phenyldiguanide-induced reflex response in anaesthetized rats.
Topics: Anesthetics, Intravenous; Animals; Apnea; Aprotinin; Biguanides; Bradycardia; Drug Synergism; Female | 1999 |
Cardiovascular and respiratory responses to right atrial injections of phenyl diguanide in pentobarbital-anesthetized newborn piglets.
Topics: Anesthesia, Inhalation; Animals; Animals, Newborn; Aorta; Apnea; Biguanides; Blood Pressure; Bradyca | 1979 |
The respiratory response to stimulation of juxta-pulmonary capillary receptors in the non-anesthetized cat.
Topics: Anesthesia; Animals; Aorta; Apnea; Arousal; Biguanides; Capillaries; Cats; Dose-Response Relationshi | 1985 |